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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:lignan
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Accession:CHEBI:25036 term browser browse the term
Definition:Any phenylpropanoid derived from phenylalanine via dimerization of substituted cinnamic alcohols, known as monolignols, to a dibenzylbutane skeleton. Note that while individual members of the class have names ending ...lignane, ...lignene, ...lignadiene, etc., the class names lignan, neolignan, etc., do not end with an 'e'.
Synonyms:related_synonym: lignans
 alt_id: CHEBI:25035;   MESH:D017705
 xref_mesh: MESH:D017705


show annotations for term's descendants           Sort by:
lignan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Lignans analog results in increased expression of BAX protein; Lignans results in increased expression of BAX protein CTD PMID:26620693 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Lignans analog results in decreased expression of BCL2 protein; Lignans results in decreased expression of BCL2 protein CTD PMID:26620693 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression ISO Lignans results in decreased expression of ERBB2 protein CTD PMID:15897583 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO Lignans results in increased expression of GSTM1 mRNA CTD PMID:26678224 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions
decreases expression		 ISO Lignans inhibits the reaction [Asbestos, Crocidolite results in increased expression of HMGB1 protein]
Lignans results in decreased expression of HMGB1 mRNA		 CTD PMID:26678224 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Lignans results in increased expression of HMOX1 mRNA CTD PMID:26678224 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression		 ISO Lignans inhibits the reaction [Asbestos, Crocidolite results in increased expression of IL1B protein]
Lignans results in decreased expression of IL1B mRNA		 CTD PMID:26678224 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression		 ISO Lignans inhibits the reaction [Asbestos, Crocidolite results in increased expression of IL6 protein]
Lignans results in decreased expression of IL6 mRNA		 CTD PMID:26678224 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO Lignans results in decreased expression of MKI67 protein CTD PMID:15897583 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO Lignans results in decreased expression of NOS2 mRNA CTD PMID:26678224 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Lignans results in increased expression of NQO1 mRNA CTD PMID:26678224 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Lignans metabolite results in increased activity of NR1I2 protein CTD PMID:15885729 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Lignans analog results in increased cleavage of PARP1 protein CTD PMID:26620693 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases expression		 ISO Lignans inhibits the reaction [Asbestos, Crocidolite results in increased expression of TGFB1 protein]
Lignans results in decreased expression of TGFB1 mRNA		 CTD PMID:26678224 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 decreases expression ISO Lignans results in decreased expression of TGFBR1 mRNA CTD PMID:26678224 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression		 ISO Lignans inhibits the reaction [Asbestos, Crocidolite results in increased expression of TNF protein]
Lignans results in decreased expression of TNF mRNA		 CTD PMID:26678224 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression ISO Lignans analog results in increased expression of TNFRSF1A protein; Lignans results in increased expression of TNFRSF1A protein CTD PMID:26620693 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
(+)-Eudesmin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO eudesmin results in decreased phosphorylation of AKT1 protein CTD PMID:31026422 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO eudesmin results in decreased expression of EZH2 mRNA; eudesmin results in decreased expression of EZH2 protein CTD PMID:31026422 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
(+)-isolariciresinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnf1a HNF1 homeobox A decreases expression ISO isolariciresinol results in decreased expression of HNF1A mRNA CTD PMID:35755389 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Ldlr low density lipoprotein receptor decreases expression ISO isolariciresinol results in decreased expression of LDLR protein CTD PMID:35755389 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 decreases expression ISO isolariciresinol results in decreased expression of PCSK9 mRNA; isolariciresinol results in decreased expression of PCSK9 protein CTD PMID:35755389 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO isolariciresinol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:21191767 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO isolariciresinol results in decreased expression of SREBF1 mRNA CTD PMID:35755389 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 decreases expression ISO isolariciresinol results in decreased expression of SREBF2 mRNA CTD PMID:35755389 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
(+)-lariciresinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 increases expression ISO lariciresinol results in increased expression of ANXA1 protein CTD PMID:27417256 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 decreases expression ISO lariciresinol results in decreased expression of BASP1 protein CTD PMID:27417256 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043 		JBrowse link
G Gale UDP-galactose-4-epimerase increases expression ISO lariciresinol results in increased expression of GALE protein CTD PMID:27417256 NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388 		JBrowse link
G Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic increases expression ISO lariciresinol results in increased expression of GAPDHS protein CTD PMID:27417256 NCBI chr 1:85,979,096...85,994,153
Ensembl chr 1:85,979,098...85,993,640 		JBrowse link
G Hp haptoglobin decreases expression ISO lariciresinol results in decreased expression of HP protein CTD PMID:27417256 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression ISO lariciresinol results in decreased expression of HSPB1 protein CTD PMID:27417256 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Tmod2 tropomodulin 2 decreases expression ISO lariciresinol results in decreased expression of TMOD2 protein CTD PMID:27417256 NCBI chr 8:76,316,736...76,366,003
Ensembl chr 8:76,325,667...76,365,720 		JBrowse link
G Tuba1a tubulin, alpha 1A decreases expression ISO lariciresinol results in decreased expression of TUBA1A protein CTD PMID:27417256 NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186 		JBrowse link
G Ubc ubiquitin C increases expression ISO lariciresinol results in increased expression of UBC protein CTD PMID:27417256 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925 		JBrowse link
(+)-pinoresinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions
decreases expression		 ISO [loliolide co-treated with pinoresinol] results in decreased expression of ACACA protein
pinoresinol results in decreased expression of ACACA protein		 CTD PMID:31610126 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Fasn fatty acid synthase multiple interactions
decreases expression		 ISO [loliolide co-treated with pinoresinol] results in decreased expression of FASN protein
pinoresinol results in decreased expression of FASN protein		 CTD PMID:31610126 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 multiple interactions ISO pinoresinol results in increased ubiquitination of and results in increased degradation of and results in decreased expression of NR1H2 protein CTD PMID:31610126 NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO pinoresinol results in increased ubiquitination of and results in increased degradation of and results in decreased expression of NR1H3 protein CTD PMID:31610126 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO pinoresinol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:21191767 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression
multiple interactions		 ISO pinoresinol results in decreased expression of SREBF1 protein
[loliolide co-treated with pinoresinol] results in decreased expression of SREBF1 protein		 CTD PMID:31610126 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Tnf tumor necrosis factor decreases secretion ISO pinoresinol results in decreased secretion of TNF protein CTD PMID:29740324 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
(+)-sesamin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO [sesamin affects the activity of ABCB1 protein] which results in increased abundance of Daunorubicin CTD PMID:18204840 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions EXP sesamin affects the reaction [Glucose affects the localization of AIFM1 protein] CTD PMID:22524206 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP		 sesamin inhibits the reaction [nickel sulfate results in increased expression of BAX protein]
sesamin affects the reaction [Glucose affects the expression of BAX protein]		 CTD PMID:22524206 PMID:23317420 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO
EXP		 sesamin inhibits the reaction [nickel sulfate results in decreased expression of BCL2 protein]
sesamin affects the reaction [Glucose affects the expression of BCL2 protein]		 CTD PMID:22524206 PMID:23317420 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP		 sesamin inhibits the reaction [nickel sulfate results in increased cleavage of CASP3 protein]
sesamin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]		 CTD PMID:22524206 PMID:23317420 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase decreases activity
multiple interactions		 EXP
ISO		 sesamin results in decreased activity of CAT protein
sesamin inhibits the reaction [nickel sulfate results in decreased activity of CAT protein]
sesamin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CAT protein]; sesamin inhibits the reaction [Doxorubicin results in decreased activity of CAT protein]		 CTD PMID:19794909 PMID:23317420 PMID:26825964 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cdh1 cadherin 1 increases expression ISO sesamin results in increased expression of CDH1 mRNA; sesamin results in increased expression of CDH1 protein CTD PMID:33561518 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Ctnnb1 catenin beta 1 increases expression ISO sesamin results in increased expression of CTNNB1 mRNA; sesamin results in increased expression of CTNNB1 protein CTD PMID:33561518 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Fads1 fatty acid desaturase 1 decreases activity EXP sesamin results in decreased activity of FADS1 protein CTD PMID:14974737 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734 		JBrowse link
G Gsr glutathione-disulfide reductase increases activity EXP sesamin results in increased activity of GSR protein CTD PMID:19835851 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO sesamin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of IL1B mRNA]; sesamin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of IL1B protein] CTD PMID:22919443 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP		 sesamin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of IL6 mRNA]; sesamin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of IL6 protein] CTD PMID:19794909 PMID:22919443 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression
multiple interactions		 EXP sesamin results in decreased expression of NOS2 protein
sesamin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NOS2 protein]		 CTD PMID:19794909 PMID:22919443 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP sesamin inhibits the reaction [Glucose results in increased cleavage of PARP1 protein] CTD PMID:22524206 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [sesamin inhibits the reaction [Doxorubicin results in decreased expression of and results in decreased activity of SOD2 protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [sesamin results in increased expression of and results in increased activity of SOD2 protein]; sesamin inhibits the reaction [Doxorubicin results in decreased expression of and results in decreased activity of SOD2 protein]; sesamin results in increased expression of and results in increased activity of SOD2 protein CTD PMID:24211423 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP sesamin inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein] CTD PMID:19794909 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO sesamin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of TNF mRNA]; sesamin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of TNF protein] CTD PMID:22919443 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
(+)-syringaresinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO syringaresinol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:21191767 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
(+)-syringaresinol beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of ACHE protein] CTD PMID:31077737 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO [acanthoside B co-treated with Scopolamine] results in increased expression of BDNF protein CTD PMID:31077737 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Cat catalase multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in decreased activity of CAT protein] CTD PMID:31077737 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in decreased phosphorylation of CREB1 protein] CTD PMID:31077737 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in decreased expression of IL10 protein] CTD PMID:31077737 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of IL1B protein] CTD PMID:31077737 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of IL6 protein] CTD PMID:31077737 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of NOS2 protein] CTD PMID:31077737 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO [acanthoside B co-treated with Scopolamine] results in increased phosphorylation of NTRK2 protein CTD PMID:31077737 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of PTGS2 protein] CTD PMID:31077737 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO acanthoside B inhibits the reaction [Scopolamine results in increased expression of TNF protein] CTD PMID:31077737 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
(-)-Arctigenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipor1 adiponectin receptor 1 multiple interactions ISO arctigenin binds to and results in increased activity of ADIPOR1 protein CTD PMID:23691032 NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [Quercetin co-treated with arctigenin] results in decreased expression of AKT1 protein; arctigenin promotes the reaction [Quercetin results in decreased phosphorylation of AKT1 protein]; arctigenin results in decreased expression of and results in decreased phosphorylation of AKT1 protein; Quercetin promotes the reaction [arctigenin results in decreased phosphorylation of AKT1 protein] CTD PMID:25380086 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt1s1 AKT1 substrate 1 decreases phosphorylation
multiple interactions		 ISO arctigenin results in decreased phosphorylation of AKT1S1 protein
Quercetin promotes the reaction [arctigenin results in decreased phosphorylation of AKT1S1 protein]		 CTD PMID:25380086 NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677 		JBrowse link
G Ar androgen receptor decreases expression
multiple interactions		 ISO arctigenin results in decreased expression of AR protein
[Quercetin co-treated with arctigenin] results in decreased expression of AR protein		 CTD PMID:25380086 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions
increases expression
decreases phosphorylation		 ISO Quercetin promotes the reaction [arctigenin results in decreased phosphorylation of BAD protein]
arctigenin results in increased expression of BAD mRNA		 CTD PMID:25380086 PMID:25922263 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO arctigenin results in decreased expression of BIRC5 mRNA CTD PMID:20510325 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Casp9 caspase 9 increases expression ISO arctigenin results in increased expression of CASP9 mRNA CTD PMID:25922263 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO arctigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CCL2 protein] CTD PMID:21426947 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO arctigenin results in decreased expression of CCND1 mRNA; arctigenin results in decreased expression of CCND1 protein CTD PMID:20510325 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO arctigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of CHUK protein] CTD PMID:21048310 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
decreases expression		 ISO arctigenin results in increased phosphorylation of and results in decreased expression of CTNNB1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arctigenin results in decreased expression of CTNNB1 protein]
arctigenin results in decreased expression of CTNNB1 mRNA		 CTD PMID:20510325 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
decreases phosphorylation		 ISO Quercetin promotes the reaction [arctigenin results in decreased phosphorylation of GSK3B protein] CTD PMID:25380086 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases secretion ISO arctigenin results in decreased secretion of ICAM1 protein CTD PMID:29740324 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ifng interferon gamma multiple interactions ISO arctigenin inhibits the reaction [IFNG results in increased expression of STAT1 protein] CTD PMID:25100250 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases secretion		 ISO arctigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL1B protein]
arctigenin results in decreased secretion of IL1B protein		 CTD PMID:21426947 PMID:29740324 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO arctigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein]
arctigenin inhibits the reaction [IL6 results in increased expression of STAT3 protein]		 CTD PMID:21426947 PMID:25100250 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Itgal integrin subunit alpha L decreases secretion ISO arctigenin results in decreased secretion of ITGAL protein CTD PMID:29740324 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732 		JBrowse link
G Itgb2 integrin subunit beta 2 decreases secretion ISO arctigenin results in decreased secretion of ITGB2 protein CTD PMID:29740324 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO arctigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of JAK2 protein] CTD PMID:21426947 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 multiple interactions
decreases expression		 ISO Quercetin inhibits the reaction [arctigenin results in decreased expression of KLK3 mRNA]; Quercetin inhibits the reaction [arctigenin results in decreased expression of KLK3 protein]
arctigenin results in decreased expression of KLK3 mRNA; arctigenin results in decreased expression of KLK3 protein		 CTD PMID:25380086 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO arctigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:21048310 PMID:29740324 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO arctigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:21048310 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO arctigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:21048310 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mir148a microRNA 148a multiple interactions
decreases expression		 ISO arctigenin promotes the reaction [Quercetin results in decreased expression of MIR148A mRNA]; Quercetin promotes the reaction [arctigenin results in decreased expression of MIR148A mRNA] CTD PMID:25380086 NCBI chr 4:80,333,762...80,333,858
Ensembl chr 4:80,333,762...80,333,858 		JBrowse link
G Mir21 microRNA 21 multiple interactions
decreases expression		 ISO arctigenin inhibits the reaction [Quercetin results in increased expression of MIR21 mRNA]
arctigenin results in decreased expression of MIR21 mRNA		 CTD PMID:25380086 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
decreases phosphorylation		 ISO Quercetin promotes the reaction [arctigenin results in decreased phosphorylation of MTOR protein] CTD PMID:25380086 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO arctigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein] CTD PMID:21048310 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nkx3-1 NK3 homeobox 1 multiple interactions
increases expression		 ISO [Quercetin co-treated with arctigenin] results in increased expression of NKX3-1 protein
arctigenin results in increased expression of NKX3-1 protein		 CTD PMID:25380086 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO arctigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; arctigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein]; arctigenin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:21048310 PMID:21426947 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases phosphorylation ISO arctigenin results in decreased phosphorylation of PPARA protein CTD PMID:23691032 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation ISO arctigenin results in increased phosphorylation of PRKAA1 protein CTD PMID:23691032 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 increases phosphorylation ISO arctigenin results in increased phosphorylation of PRKAA2 protein CTD PMID:23691032 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO arctigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein]; arctigenin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:21048310 PMID:21426947 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Sele selectin E decreases secretion ISO arctigenin results in decreased secretion of SELE protein CTD PMID:29740324 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO arctigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of and affects the localization of STAT1 protein]
arctigenin inhibits the reaction [IFNG results in increased expression of STAT1 protein]		 CTD PMID:21426947 PMID:25100250 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
decreases phosphorylation		 ISO arctigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of and affects the localization of STAT3 protein]
arctigenin inhibits the reaction [IL6 results in increased expression of STAT3 protein]; Quercetin promotes the reaction [arctigenin results in decreased phosphorylation of STAT3 protein]		 CTD PMID:21426947 PMID:25100250 PMID:25380086 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tnf tumor necrosis factor decreases secretion ISO arctigenin results in decreased secretion of TNF protein CTD PMID:29740324 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
(-)-bursehernin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 affects binding ISO bursehernin binds to ESR1 protein CTD PMID:35631411 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
(-)-lariciresinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 increases expression ISO lariciresinol results in increased expression of ANXA1 protein CTD PMID:27417256 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 decreases expression ISO lariciresinol results in decreased expression of BASP1 protein CTD PMID:27417256 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043 		JBrowse link
G Gale UDP-galactose-4-epimerase increases expression ISO lariciresinol results in increased expression of GALE protein CTD PMID:27417256 NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388 		JBrowse link
G Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic increases expression ISO lariciresinol results in increased expression of GAPDHS protein CTD PMID:27417256 NCBI chr 1:85,979,096...85,994,153
Ensembl chr 1:85,979,098...85,993,640 		JBrowse link
G Hp haptoglobin decreases expression ISO lariciresinol results in decreased expression of HP protein CTD PMID:27417256 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression ISO lariciresinol results in decreased expression of HSPB1 protein CTD PMID:27417256 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Tmod2 tropomodulin 2 decreases expression ISO lariciresinol results in decreased expression of TMOD2 protein CTD PMID:27417256 NCBI chr 8:76,316,736...76,366,003
Ensembl chr 8:76,325,667...76,365,720 		JBrowse link
G Tuba1a tubulin, alpha 1A decreases expression ISO lariciresinol results in decreased expression of TUBA1A protein CTD PMID:27417256 NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186 		JBrowse link
G Ubc ubiquitin C increases expression ISO lariciresinol results in increased expression of UBC protein CTD PMID:27417256 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925 		JBrowse link
(-)-matairesinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO [matairesinol affects the activity of ABCB1 protein] which results in increased abundance of Daunorubicin CTD PMID:18204840 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [matairesinol affects the activity of ABCC1 protein] which results in increased abundance of fluorexon CTD PMID:18204840 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant decreases activity ISO matairesinol results in decreased activity of ACP5 protein CTD PMID:24444335 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Adipor1 adiponectin receptor 1 multiple interactions ISO matairesinol binds to and results in increased activity of ADIPOR1 protein CTD PMID:23691032 NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO matairesinol results in increased expression of BAX mRNA CTD PMID:25922263 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [matairesinol co-treated with TNFSF10 protein modified form] results in increased cleavage of BID CTD PMID:19935713 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO [matairesinol co-treated with TNFSF10 protein modified form] results in increased activity of CASP3 protein CTD PMID:19935713 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases expression ISO matairesinol results in increased expression of CASP9 mRNA CTD PMID:25922263 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO matairesinol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of CHUK protein] CTD PMID:21048310 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Ctnnb1 catenin beta 1 decreases expression ISO matairesinol results in decreased expression of CTNNB1 protein CTD PMID:20510325 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions ISO CYP17A1 gene SNP affects the susceptibility to [Phytoestrogens results in increased abundance of matairesinol] CTD PMID:16702327 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Esr1 estrogen receptor 1 affects binding ISO matairesinol binds to ESR1 protein CTD PMID:35631411 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Ifng interferon gamma multiple interactions ISO matairesinol inhibits the reaction [Antigens, Dermatophagoides results in decreased expression of IFNG mRNA] CTD PMID:27085937 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO matairesinol inhibits the reaction [Antigens, Dermatophagoides results in increased expression of IL4 mRNA] CTD PMID:27085937 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO matairesinol inhibits the reaction [IL6 results in increased expression of STAT3 protein] CTD PMID:25100250 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO matairesinol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:21048310 PMID:28512713 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO matairesinol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:21048310 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO matairesinol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:21048310 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO matairesinol inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA] CTD PMID:24444335 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO matairesinol inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased abundance of Nitric Oxide]; matairesinol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:21048310 PMID:28512713 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases phosphorylation ISO matairesinol results in decreased phosphorylation of PPARA protein CTD PMID:23691032 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation ISO matairesinol results in increased phosphorylation of PRKAA1 protein CTD PMID:23691032 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 increases phosphorylation ISO matairesinol results in increased phosphorylation of PRKAA2 protein CTD PMID:23691032 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO matairesinol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:21048310 PMID:28512713 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO matairesinol inhibits the reaction [Lipopolysaccharides results in increased activity of and results in increased localization of RELA protein] CTD PMID:28512713 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO matairesinol inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of SRC protein] CTD PMID:28512713 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO matairesinol inhibits the reaction [IL6 results in increased expression of STAT3 protein] CTD PMID:25100250 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tnf tumor necrosis factor decreases secretion ISO matairesinol results in decreased secretion of TNF protein CTD PMID:29740324 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [matairesinol co-treated with TNFSF10 protein modified form] results in increased activity of CASP3 protein; [matairesinol co-treated with TNFSF10 protein modified form] results in increased cleavage of BID CTD PMID:19935713 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO matairesinol inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA] CTD PMID:24444335 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
(-)-secoisolariciresinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO secoisolariciresinol results in increased activity of NR1I2 protein CTD PMID:15885729 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
2,3-Bis(3-hydroxybenzyl)butane-1,4-diol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol results in decreased activity of CYP19A1 protein CTD PMID:15876411 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Kdr kinase insert domain receptor multiple interactions ISO 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol inhibits the reaction [Estradiol results in increased expression of KDR protein] CTD PMID:17289903 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol inhibits the reaction [Estradiol results in increased secretion of VEGFA protein] CTD PMID:17289903 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
Arctiin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipor1 adiponectin receptor 1 multiple interactions ISO arctiin binds to and results in increased activity of ADIPOR1 protein CTD PMID:23691032 NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO arctiin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of CHUK protein] CTD PMID:21048310 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Il6 interleukin 6 decreases expression EXP arctiin results in decreased expression of IL6 protein CTD PMID:19524415 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO arctiin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:21048310 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO arctiin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:21048310 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO arctiin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] CTD PMID:21048310 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO arctiin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein] CTD PMID:21048310 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO arctiin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:21048310 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases phosphorylation ISO arctiin results in decreased phosphorylation of PPARA protein CTD PMID:23691032 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation ISO arctiin results in increased phosphorylation of PRKAA1 protein CTD PMID:23691032 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 increases phosphorylation ISO arctiin results in increased phosphorylation of PRKAA2 protein CTD PMID:23691032 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO arctiin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:21048310 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Tnf tumor necrosis factor decreases expression EXP arctiin results in decreased expression of TNF protein CTD PMID:19524415 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
deoxypodophyllotoxin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha increases phosphorylation
multiple interactions		 ISO deoxypodophyllotoxin results in increased phosphorylation of ACACA protein
deoxypodophyllotoxin inhibits the reaction [Dietary Fats results in decreased phosphorylation of ACACA protein]
deoxypodophyllotoxin inhibits the reaction [T0901317 results in increased expression of ACACA mRNA]		 CTD PMID:30148990 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Fasn fatty acid synthase multiple interactions ISO deoxypodophyllotoxin inhibits the reaction [T0901317 results in increased expression of FASN mRNA] CTD PMID:30148990 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO deoxypodophyllotoxin inhibits the reaction [Dietary Fats results in increased activity of GPT protein] CTD PMID:30148990 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO deoxypodophyllotoxin inhibits the reaction [T0901317 results in increased expression of SCD mRNA] CTD PMID:30148990 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO deoxypodophyllotoxin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 protein]
deoxypodophyllotoxin inhibits the reaction [T0901317 results in increased expression of SREBF1 mRNA]; deoxypodophyllotoxin inhibits the reaction [T0901317 results in increased expression of SREBF1 protein]; dorsomorphin inhibits the reaction [deoxypodophyllotoxin inhibits the reaction [T0901317 results in increased expression of SREBF1 protein]]		 CTD PMID:30148990 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Stk11 serine/threonine kinase 11 increases phosphorylation ISO deoxypodophyllotoxin results in increased phosphorylation of STK11 protein CTD PMID:30148990 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315 		JBrowse link
Enterolactone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 6430548M08Rikl RIKEN cDNA 6430548M08 gene like multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of KIAA0513 mRNA CTD PMID:19167446 NCBI chr19:48,168,651...48,216,571
Ensembl chr19:48,198,209...48,216,575 		JBrowse link
G Aaas aladin WD repeat nucleoporin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of AAAS mRNA CTD PMID:19167446 NCBI chr 7:133,464,315...133,483,961
Ensembl chr 7:133,464,315...133,483,961 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ABCC5 mRNA CTD PMID:19167446 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253 		JBrowse link
G Abcf1 ATP binding cassette subfamily F member 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ABCF1 mRNA CTD PMID:19167446 NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ABCG1 mRNA CTD PMID:19167446 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948 		JBrowse link
G Abhd11 abhydrolase domain containing 11 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ABHD11 mRNA CTD PMID:19167446 NCBI chr12:21,682,206...21,685,331
Ensembl chr12:21,682,202...21,685,398 		JBrowse link
G Abhd12 abhydrolase domain containing 12, lysophospholipase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ABHD12 mRNA CTD PMID:19167446 NCBI chr 3:139,659,315...139,719,529
Ensembl chr 3:139,659,317...139,719,564 		JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase decreases expression ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of ABHD2 mRNA CTD PMID:19167446 NCBI chr 1:133,217,403...133,298,564
Ensembl chr 1:133,217,375...133,299,061 		JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ACAA2 mRNA CTD PMID:19167446 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ACAT2 mRNA CTD PMID:19167446 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Acbd3 acyl-CoA binding domain containing 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ACBD3 mRNA CTD PMID:19167446 NCBI chr13:92,455,813...92,484,556
Ensembl chr13:92,455,655...92,483,380 		JBrowse link
G Ackr3 atypical chemokine receptor 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ACKR3 mRNA CTD PMID:19167446 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237 		JBrowse link
G Acly ATP citrate lyase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ACLY mRNA CTD PMID:19167446 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320 		JBrowse link
G Acot4 acyl-CoA thioesterase 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ACOT4 mRNA CTD PMID:19167446 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917 		JBrowse link
G Acot7 acyl-CoA thioesterase 7 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ACOT7 mRNA CTD PMID:19167446 NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309 		JBrowse link
G Acyp1 acylphosphatase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ACYP1 mRNA CTD PMID:19167446 NCBI chr 6:104,919,162...104,932,348
Ensembl chr 6:104,919,162...104,932,387 		JBrowse link
G Adat1 adenosine deaminase, tRNA-specific 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ADAT1 mRNA CTD PMID:19167446 NCBI chr19:39,918,083...39,956,886
Ensembl chr19:39,918,227...39,956,883 		JBrowse link
G Add3 adducin 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ADD3 mRNA CTD PMID:19167446 NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124 		JBrowse link
G Afap1 actin filament associated protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of AFAP1 mRNA CTD PMID:19167446 NCBI chr14:74,743,322...74,856,300
Ensembl chr14:74,743,320...74,856,263 		JBrowse link
G Aff4 ALF transcription elongation factor 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of AFF4 mRNA CTD PMID:19167446 NCBI chr10:37,498,825...37,579,751
Ensembl chr10:37,498,825...37,579,751 		JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of AGR2 mRNA CTD PMID:19167446 NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371 		JBrowse link
G Agr3 anterior gradient 3, protein disulphide isomerase family member multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of AGR3 mRNA CTD PMID:19167446 NCBI chr 6:52,643,391...52,666,638
Ensembl chr 6:52,643,391...52,666,638 		JBrowse link
G Ajuba ajuba LIM protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of AJUBA mRNA CTD PMID:19167446 NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021 		JBrowse link
G Akap13 A-kinase anchoring protein 13 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of AKAP13 mRNA CTD PMID:19167446 NCBI chr 1:129,313,183...129,619,647
Ensembl chr 1:129,314,402...129,619,646 		JBrowse link
G Alg6 ALG6, alpha-1,3-glucosyltransferase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ALG6 mRNA CTD PMID:19167446 NCBI chr 5:114,404,972...114,454,440
Ensembl chr 5:114,405,010...114,454,439 		JBrowse link
G Alg8 ALG8, alpha-1,3-glucosyltransferase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ALG8 mRNA CTD PMID:19167446 NCBI chr 1:151,684,344...151,704,310
Ensembl chr 1:151,684,396...151,704,302 		JBrowse link
G Amd1 adenosylmethionine decarboxylase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of AMD1 mRNA CTD PMID:19167446 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476 		JBrowse link
G Ammecr1 AMMECR nuclear protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of AMMECR1 mRNA CTD PMID:19167446 NCBI chr  X:106,465,982...106,571,382
Ensembl chr  X:106,466,699...106,571,487 		JBrowse link
G Amotl2 angiomotin like 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of AMOTL2 mRNA CTD PMID:19167446 NCBI chr 8:103,303,368...103,319,161
Ensembl chr 8:103,302,992...103,318,910 		JBrowse link
G Anln anillin, actin binding protein multiple interactions
increases expression		 ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ANLN mRNA
2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased expression of ANLN mRNA		 CTD PMID:19167446 NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538 		JBrowse link
G Ano6 anoctamin 6 decreases expression
multiple interactions		 ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of ANO6 mRNA
[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ANO6 mRNA		 CTD PMID:19167446 NCBI chr 7:126,933,919...127,113,588
Ensembl chr 7:126,933,936...127,113,589 		JBrowse link
G Anp32e acidic nuclear phosphoprotein 32 family member E multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ANP32E mRNA CTD PMID:19167446 NCBI chr 2:183,472,600...183,489,057
Ensembl chr 2:183,472,609...183,489,054 		JBrowse link
G Anxa2 annexin A2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ANXA2 mRNA CTD PMID:19167446 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Anxa3 annexin A3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ANXA3 mRNA CTD PMID:19167446 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617 		JBrowse link
G Anxa9 annexin A9 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ANXA9 mRNA CTD PMID:19167446 NCBI chr 2:182,873,185...182,884,501
Ensembl chr 2:182,872,929...182,883,374 		JBrowse link
G Ap1b1 adaptor related protein complex 1 subunit beta 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of AP1B1 mRNA CTD PMID:19167446 NCBI chr14:79,879,482...79,930,778
Ensembl chr14:79,879,533...79,930,778 		JBrowse link
G Ap1m1 adaptor related protein complex 1 subunit mu 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of AP1M1 mRNA CTD PMID:19167446 NCBI chr16:17,586,886...17,602,410
Ensembl chr16:17,584,730...17,602,403 		JBrowse link
G Apbb2 amyloid beta precursor protein binding family B member 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of APBB2 mRNA CTD PMID:19167446 NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,557,972...41,877,495 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of AQP3 mRNA CTD PMID:19167446 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720 		JBrowse link
G Arfgef3 ARFGEF family member 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ARFGEF3 mRNA CTD PMID:19167446 NCBI chr 1:13,245,578...13,404,319
Ensembl chr 1:13,244,830...13,404,084 		JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ARHGDIA mRNA CTD PMID:19167446 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023 		JBrowse link
G Arhgef26 Rho guanine nucleotide exchange factor 26 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ARHGEF26 mRNA CTD PMID:19167446 NCBI chr 2:146,740,336...146,850,918
Ensembl chr 2:146,739,631...146,850,819 		JBrowse link
G Arhgef37 Rho guanine nucleotide exchange factor 37 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ARHGEF37 mRNA CTD PMID:19167446 NCBI chr18:54,935,256...55,001,017
Ensembl chr18:54,949,110...55,000,669 		JBrowse link
G Arl3 ADP ribosylation factor like GTPase 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ARL3 mRNA CTD PMID:19167446 NCBI chr 1:245,400,659...245,446,673
Ensembl chr 1:245,400,550...245,446,820 		JBrowse link
G Arx aristaless related homeobox multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ARX mRNA CTD PMID:19167446 NCBI chr  X:58,016,233...58,028,149
Ensembl chr  X:58,016,233...58,028,142 		JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ASAP1 mRNA CTD PMID:19167446 NCBI chr 7:95,786,130...96,093,111
Ensembl chr 7:95,787,818...96,092,754 		JBrowse link
G Asf1b anti-silencing function 1B histone chaperone multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ASF1B mRNA CTD PMID:19167446 NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549 		JBrowse link
G Aspm assembly factor for spindle microtubules multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ASPM mRNA CTD PMID:19167446 NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755 		JBrowse link
G Atad2 ATPase family, AAA domain containing 2 multiple interactions
increases expression		 ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ATAD2 mRNA
2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased expression of ATAD2 mRNA		 CTD PMID:19167446 NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738 		JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ATF3 mRNA CTD PMID:19167446 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf5 activating transcription factor 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ATF5 mRNA CTD PMID:19167446 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707 		JBrowse link
G Atosa atos homolog A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ATOSA mRNA CTD PMID:19167446 NCBI chr 8:75,694,828...75,772,565
Ensembl chr 8:75,695,022...75,772,549 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ATP1B1 mRNA CTD PMID:19167446 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459 		JBrowse link
G Atp23 ATP23 metallopeptidase and ATP synthase assembly factor homolog multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ATP23 mRNA CTD PMID:19167446 NCBI chr 7:62,714,752...62,729,893
Ensembl chr 7:62,714,785...62,729,862 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ATP2B1 mRNA CTD PMID:19167446 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295 		JBrowse link
G Atp2c1 ATPase secretory pathway Ca2+ transporting 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ATP2C1 mRNA CTD PMID:19167446 NCBI chr 8:106,034,777...106,155,854
Ensembl chr 8:106,034,636...106,156,006 		JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ATP5MC1 mRNA CTD PMID:19167446 NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124 		JBrowse link
G Atp6v0e1 ATPase H+ transporting V0 subunit e1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ATP6V0E1 mRNA CTD PMID:19167446 NCBI chr10:16,479,656...16,502,732
Ensembl chr10:16,479,567...16,524,434 		JBrowse link
G Atp9a ATPase phospholipid transporting 9A (putative) multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ATP9A mRNA CTD PMID:19167446 NCBI chr 3:157,360,354...157,467,628
Ensembl chr 3:157,360,359...157,467,818 		JBrowse link
G Atrx ATRX, chromatin remodeler decreases expression ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of ATRX mRNA CTD PMID:19167446 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Atxn1 ataxin 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ATXN1 mRNA CTD PMID:19167446 NCBI chr17:18,737,491...19,142,360
Ensembl chr17:18,737,533...19,142,360 		JBrowse link
G Aurka aurora kinase A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of AURKA mRNA CTD PMID:19167446 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390 		JBrowse link
G Aurkb aurora kinase B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of AURKB mRNA CTD PMID:19167446 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G B3galnt1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of B3GALNT1 mRNA CTD PMID:19167446 NCBI chr 2:153,847,297...153,877,371
Ensembl chr 2:153,846,474...153,877,332 		JBrowse link
G B3gnt5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of B3GNT5 mRNA CTD PMID:19167446 NCBI chr11:81,141,102...81,153,206
Ensembl chr11:81,140,599...81,156,166 		JBrowse link
G Bace1 beta-secretase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of BACE1 mRNA CTD PMID:19167446 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Bace2 beta-secretase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of BACE2 mRNA CTD PMID:19167446 NCBI chr11:36,707,447...36,789,550
Ensembl chr11:36,707,458...36,789,546 		JBrowse link
G Bag3 BAG cochaperone 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of BAG3 mRNA CTD PMID:19167446 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858 		JBrowse link
G Bard1 BRCA1 associated RING domain 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of BARD1 mRNA CTD PMID:19167446 NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265 		JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of BCAR3 mRNA CTD PMID:19167446 NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of BCL2 mRNA CTD PMID:19167446 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l12 Bcl2 like 12 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of BCL2L12 mRNA CTD PMID:19167446 NCBI chr 1:95,472,272...95,480,991
Ensembl chr 1:95,472,272...95,480,991 		JBrowse link
G Bcl3 BCL3, transcription coactivator multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of BCL3 mRNA CTD PMID:19167446 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G Bcl9 BCL9, transcription coactivator multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of BCL9 mRNA CTD PMID:19167446 NCBI chr 2:184,760,616...184,846,261
Ensembl chr 2:184,760,618...184,786,435 		JBrowse link
G Bex1 brain expressed X-linked 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of BEX2 mRNA CTD PMID:19167446 NCBI chr  X:99,219,014...99,220,518
Ensembl chr  X:99,219,014...99,220,958 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of BHLHE40 mRNA CTD PMID:19167446 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of BIRC5 mRNA CTD PMID:19167446 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Blm BLM RecQ like helicase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of BLM mRNA CTD PMID:19167446 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Blnk B-cell linker multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of BLNK mRNA CTD PMID:19167446 NCBI chr 1:239,753,640...239,821,113
Ensembl chr 1:239,753,648...239,821,113 		JBrowse link
G Bltp2 bridge-like lipid transfer protein family member 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of BLTP2 mRNA CTD PMID:19167446 NCBI chr10:63,155,999...63,185,213
Ensembl chr10:63,156,044...63,191,141 		JBrowse link
G Bmerb1 bMERB domain containing 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of BMERB1 mRNA CTD PMID:19167446 NCBI chr10:1,779,834...1,946,586
Ensembl chr10:1,779,835...1,946,575 		JBrowse link
G Bmf Bcl2 modifying factor multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of BMF mRNA CTD PMID:19167446 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145 		JBrowse link
G Bmp7 bone morphogenetic protein 7 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of BMP7 mRNA CTD PMID:19167446 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of BMPR2 mRNA CTD PMID:19167446 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Brat1 BRCA1-associated ATM activator 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of BRAT1 mRNA CTD PMID:19167446 NCBI chr12:13,928,889...13,951,760
Ensembl chr12:13,928,898...13,941,248 		JBrowse link
G Brca1 BRCA1, DNA repair associated multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of BRCA1 mRNA CTD PMID:19167446 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Brca2 BRCA2, DNA repair associated multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of BRCA2 mRNA CTD PMID:19167446 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567 		JBrowse link
G Bri3bp Bri3 binding protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of BRI3BP mRNA CTD PMID:19167446 NCBI chr12:31,176,742...31,188,563
Ensembl chr12:31,173,971...31,188,572 		JBrowse link
G Brwd1 bromodomain and WD repeat domain containing 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of BRWD1 mRNA CTD PMID:19167446 NCBI chr11:35,286,364...35,378,768
Ensembl chr11:35,288,313...35,378,768 		JBrowse link
G Bsdc1 BSD domain containing 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of BSDC1 mRNA CTD PMID:19167446 NCBI chr 5:141,798,918...141,827,091
Ensembl chr 5:141,798,981...141,827,092 		JBrowse link
G Bsg basigin (Ok blood group) multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of BSG mRNA CTD PMID:19167446 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387 		JBrowse link
G Btg1 BTG anti-proliferation factor 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of BTG1 mRNA CTD PMID:19167446 NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649 		JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of BUB1B mRNA CTD PMID:19167446 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547 		JBrowse link
G C1h9orf40 similar to human chromosome 9 open reading frame 40 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of C9ORF40 mRNA CTD PMID:19167446 NCBI chr 1:216,128,687...216,132,896
Ensembl chr 1:216,128,651...216,133,045 		JBrowse link
G C2h5orf34 similar to human chromosome 5 open reading frame 34 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of C5ORF34 mRNA CTD PMID:19167446 NCBI chr 2:51,553,223...51,577,090
Ensembl chr 2:51,555,432...51,577,085 		JBrowse link
G C5 complement C5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of C5 mRNA CTD PMID:19167446 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994 		JBrowse link
G C5h9orf152 similar to human chromosome 9 open reading frame 152 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of C9ORF152 mRNA CTD PMID:19167446 NCBI chr 5:72,660,573...72,667,941
Ensembl chr 5:72,660,573...72,668,379 		JBrowse link
G Cadm1 cell adhesion molecule 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CADM1 mRNA CTD PMID:19167446 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833 		JBrowse link
G Calm3 calmodulin 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CALM3 mRNA CTD PMID:19167446 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207 		JBrowse link
G Calu calumenin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CALU mRNA CTD PMID:19167446 NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CAMK2D mRNA CTD PMID:19167446 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178 		JBrowse link
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CAMK2N1 mRNA CTD PMID:19167446 NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600 		JBrowse link
G Car12 carbonic anhydrase 12 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CA12 mRNA CTD PMID:19167446 NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440 		JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CARHSP1 mRNA CTD PMID:19167446 NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019 		JBrowse link
G Cast calpastatin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CAST mRNA CTD PMID:19167446 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659 		JBrowse link
G Cbfb core-binding factor subunit beta multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CBFB mRNA CTD PMID:19167446 NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751 		JBrowse link
G Cblb Cbl proto-oncogene B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CBLB mRNA CTD PMID:19167446 NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839 		JBrowse link
G Ccdc14 coiled-coil domain containing 14 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CCDC14 mRNA CTD PMID:19167446 NCBI chr11:66,052,063...66,087,915
Ensembl chr11:66,052,620...66,087,956 		JBrowse link
G Ccdc34 coiled-coil domain containing 34 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CCDC34 mRNA CTD PMID:19167446 NCBI chr 3:96,553,074...96,588,310
Ensembl chr 3:96,552,992...96,588,146 		JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CCN1 mRNA CTD PMID:19167446 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ccn5 cellular communication network factor 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CCN5 mRNA CTD PMID:19167446 NCBI chr 3:152,491,247...152,502,639
Ensembl chr 3:152,491,220...152,502,636 		JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CCNB1 mRNA CTD PMID:19167446 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnb2 cyclin B2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CCNB2 mRNA CTD PMID:19167446 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874 		JBrowse link
G Ccne2 cyclin E2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CCNE2 mRNA CTD PMID:19167446 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Ccnf cyclin F multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CCNF mRNA CTD PMID:19167446 NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101 		JBrowse link
G Ccpg1 cell cycle progression 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CCPG1 mRNA CTD PMID:19167446 NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) decreases expression
multiple interactions		 ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of CD55 mRNA
[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CD55 mRNA		 CTD PMID:19167446 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831 		JBrowse link
G Cd59b CD59b molecule multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CD59 mRNA CTD PMID:19167446 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847 		JBrowse link
G Cdc25a cell division cycle 25A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDC25A mRNA CTD PMID:19167446 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701 		JBrowse link
G Cdc25c cell division cycle 25C multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDC25C mRNA CTD PMID:19167446 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185 		JBrowse link
G Cdc27 cell division cycle 27 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDC27 mRNA CTD PMID:19167446 NCBI chr10:89,400,720...89,449,816
Ensembl chr10:89,400,940...89,449,736 		JBrowse link
G Cdc45 cell division cycle 45 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDC45 mRNA CTD PMID:19167446 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619 		JBrowse link
G Cdc6 cell division cycle 6 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDC6 mRNA CTD PMID:19167446 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011 		JBrowse link
G Cdc7 cell division cycle 7 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDC7 mRNA CTD PMID:19167446 NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778 		JBrowse link
G Cdca2 cell division cycle associated 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDCA2 mRNA CTD PMID:19167446 NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611 		JBrowse link
G Cdca3 cell division cycle associated 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDCA3 mRNA CTD PMID:19167446 NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799 		JBrowse link
G Cdca4 cell division cycle associated 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDCA4 mRNA CTD PMID:19167446 NCBI chr 6:131,892,305...131,901,571
Ensembl chr 6:131,892,087...131,901,564 		JBrowse link
G Cdca5 cell division cycle associated 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDCA5 mRNA CTD PMID:19167446 NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023 		JBrowse link
G Cdca7l cell division cycle associated 7 like multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDCA7L mRNA CTD PMID:19167446 NCBI chr 6:138,793,953...138,839,889
Ensembl chr 6:138,794,228...138,839,888 		JBrowse link
G Cdca8 cell division cycle associated 8 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDCA8 mRNA CTD PMID:19167446 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629 		JBrowse link
G Cdh12 cadherin 12 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDH12 mRNA CTD PMID:19167446 NCBI chr 2:70,474,679...71,705,369
Ensembl chr 2:70,475,043...71,700,572 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression
multiple interactions		 ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased expression of CDK1 mRNA
[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDK1 mRNA		 CTD PMID:19167446 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk17 cyclin-dependent kinase 17 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PCTK2 mRNA CTD PMID:19167446 NCBI chr 7:27,683,890...27,765,814
Ensembl chr 7:27,683,890...27,764,910 		JBrowse link
G Cdk2ap2 cyclin-dependent kinase 2 associated protein 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDK2AP2 mRNA CTD PMID:19167446 NCBI chr 1:201,391,056...201,393,137
Ensembl chr 1:201,391,466...201,393,137 		JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDK5RAP2 mRNA CTD PMID:19167446 NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
decreases expression		 ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CDKN1A mRNA
2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of CDKN1A mRNA		 CTD PMID:19167446 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CDKN2B mRNA CTD PMID:19167446 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDKN2C mRNA CTD PMID:19167446 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278 		JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDKN3 mRNA CTD PMID:19167446 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945 		JBrowse link
G Cds1 CDP-diacylglycerol synthase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CDS1 mRNA CTD PMID:19167446 NCBI chr14:7,820,328...7,882,943
Ensembl chr14:7,820,351...7,882,681 		JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CDT1 mRNA CTD PMID:19167446 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CEBPD mRNA CTD PMID:19167446 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829 		JBrowse link
G Celsr2 cadherin, EGF LAG seven-pass G-type receptor 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CELSR2 mRNA CTD PMID:19167446 NCBI chr 2:196,029,206...196,053,848
Ensembl chr 2:196,029,434...196,053,845 		JBrowse link
G Cenpa centromere protein A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CENPA mRNA CTD PMID:19167446 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675 		JBrowse link
G Cenpf centromere protein F multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CENPF mRNA CTD PMID:19167446 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669 		JBrowse link
G Cenph centromere protein H multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CENPH mRNA CTD PMID:19167446 NCBI chr 2:31,896,675...31,910,179
Ensembl chr 2:31,894,667...31,910,154 		JBrowse link
G Cenpi centromere protein I multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CENPI mRNA CTD PMID:19167446 NCBI chr  X:97,515,919...97,567,671
Ensembl chr  X:97,515,972...97,567,657 		JBrowse link
G Cenpl centromere protein L multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CENPL mRNA CTD PMID:19167446 NCBI chr13:73,337,235...73,352,115
Ensembl chr13:73,337,257...73,352,114 		JBrowse link
G Cenpn centromere protein N multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CENPN mRNA CTD PMID:19167446 NCBI chr19:44,971,265...44,994,019
Ensembl chr19:44,968,308...44,994,012 		JBrowse link
G Cenpo centromere protein O multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CENPO mRNA CTD PMID:19167446 NCBI chr 6:27,203,642...27,218,394
Ensembl chr 6:27,188,537...27,218,314 		JBrowse link
G Cenpq centromere protein Q multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CENPQ mRNA CTD PMID:19167446 NCBI chr 9:19,957,122...19,972,807
Ensembl chr 9:19,957,048...19,972,789 		JBrowse link
G Cenps centromere protein S multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CENPS mRNA CTD PMID:19167446 NCBI chr 5:159,563,917...159,573,534 JBrowse link
G Cenpu centromere protein U multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CENPU mRNA CTD PMID:19167446 NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823 		JBrowse link
G Cenpw centromere protein W multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CENPW mRNA CTD PMID:19167446 NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464 		JBrowse link
G Cep55 centrosomal protein 55 multiple interactions
increases expression		 ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CEP55 mRNA
2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased expression of CEP55 mRNA		 CTD PMID:19167446 NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394 		JBrowse link
G Cep57 centrosomal protein 57 increases expression ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased expression of CEP57 mRNA CTD PMID:19167446 NCBI chr 8:10,669,588...10,689,257
Ensembl chr 8:10,669,590...10,689,249 		JBrowse link
G Cep78 centrosomal protein 78 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CEP78 mRNA CTD PMID:19167446 NCBI chr 1:213,246,183...213,275,275
Ensembl chr 1:213,246,187...213,275,181 		JBrowse link
G Cep85 centrosomal protein 85 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CEP85 mRNA CTD PMID:19167446 NCBI chr 5:146,356,571...146,404,155
Ensembl chr 5:146,356,576...146,404,060 		JBrowse link
G Chac2 ChaC glutathione specific gamma-glutamylcyclotransferase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CHAC2 mRNA CTD PMID:19167446 NCBI chr14:104,720,754...104,728,305
Ensembl chr14:104,720,758...104,728,301 		JBrowse link
G Chaf1a chromatin assembly factor 1 subunit A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CHAF1A mRNA CTD PMID:19167446 NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654 		JBrowse link
G Chaf1b chromatin assembly factor 1 subunit B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CHAF1B mRNA CTD PMID:19167446 NCBI chr11:33,200,894...33,221,076
Ensembl chr11:33,200,981...33,221,070 		JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CHD2 mRNA CTD PMID:19167446 NCBI chr 1:127,188,146...127,317,041
Ensembl chr 1:127,190,059...127,300,502 		JBrowse link
G Chek1 checkpoint kinase 1 increases expression
multiple interactions		 ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased expression of CHEK1 mRNA
[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CHEK1 mRNA		 CTD PMID:19167446 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009 		JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CHEK2 mRNA CTD PMID:19167446 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Chpt1 choline phosphotransferase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CHPT1 mRNA CTD PMID:19167446 NCBI chr 7:22,866,455...22,915,111
Ensembl chr 7:22,863,027...22,915,103 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CITED2 mRNA CTD PMID:19167446 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Ckap5 cytoskeleton associated protein 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CKAP5 mRNA CTD PMID:19167446 NCBI chr 3:77,491,195...77,593,300
Ensembl chr 3:77,491,276...77,593,264 		JBrowse link
G Cklf chemokine-like factor multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CKLF mRNA CTD PMID:19167446 NCBI chr19:698,097...706,570
Ensembl chr19:698,033...706,570 		JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CKS1B mRNA CTD PMID:19167446 NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636 		JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CKS2 mRNA CTD PMID:19167446 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Cldn1 claudin 1 decreases expression
multiple interactions		 ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of CLDN1 mRNA
[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CLDN1 mRNA		 CTD PMID:19167446 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724 		JBrowse link
G Cldn4 claudin 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CLDN4 mRNA CTD PMID:19167446 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436 		JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CLIP1 mRNA CTD PMID:19167446 NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884 		JBrowse link
G Cln6 CLN6, transmembrane ER protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CLN6 mRNA CTD PMID:19167446 NCBI chr 8:63,303,356...63,318,360
Ensembl chr 8:63,303,029...63,318,360 		JBrowse link
G Clu clusterin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CLU mRNA CTD PMID:19167446 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cmc2 C-x(9)-C motif containing 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CMC2 mRNA CTD PMID:19167446 NCBI chr19:44,943,283...44,971,930
Ensembl chr19:44,943,285...44,971,983 		JBrowse link
G Col5a1 collagen type V alpha 1 chain decreases expression ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of COL5A1 mRNA CTD PMID:19167446 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588 		JBrowse link
G Cracd capping protein inhibiting regulator of actin dynamics multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CRACD mRNA CTD PMID:19167446 NCBI chr14:31,284,066...31,520,103
Ensembl chr14:31,284,184...31,522,431 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CRY1 mRNA CTD PMID:19167446 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091 		JBrowse link
G Cse1l chromosome segregation 1 like multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CSE1L mRNA CTD PMID:19167446 NCBI chr 3:155,641,104...155,678,866
Ensembl chr 3:155,641,166...155,678,865 		JBrowse link
G Cspg5 chondroitin sulfate proteoglycan 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CSPG5 mRNA CTD PMID:19167446 NCBI chr 8:110,220,506...110,234,766
Ensembl chr 8:110,220,653...110,234,758 		JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of AXUD1 mRNA CTD PMID:19167446 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183 		JBrowse link
G Csrnp2 cysteine and serine rich nuclear protein 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CSRNP2 mRNA CTD PMID:19167446 NCBI chr 7:131,594,232...131,610,075
Ensembl chr 7:131,594,232...131,610,075 		JBrowse link
G Ctdspl2 CTD small phosphatase like 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CTDSPL2 mRNA CTD PMID:19167446 NCBI chr 3:108,915,263...108,970,620
Ensembl chr 3:108,915,280...108,967,227 		JBrowse link
G Ctnnal1 catenin alpha-like 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CTNNAL1 mRNA CTD PMID:19167446 NCBI chr 5:71,514,340...71,569,431
Ensembl chr 5:71,514,340...71,569,431 		JBrowse link
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CTR9 mRNA CTD PMID:19167446 NCBI chr 1:165,137,277...165,167,303
Ensembl chr 1:165,137,215...165,167,303 		JBrowse link
G Cttn cortactin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CTTN mRNA CTD PMID:19167446 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164 		JBrowse link
G Cttnbp2nl CTTNBP2 N-terminal like multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CTTNBP2NL mRNA CTD PMID:19167446 NCBI chr 2:192,507,963...192,554,548
Ensembl chr 2:192,507,963...192,541,101 		JBrowse link
G Cxxc5 CXXC finger protein 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CXXC5 mRNA CTD PMID:19167446 NCBI chr18:27,427,591...27,458,579
Ensembl chr18:27,427,230...27,458,673 		JBrowse link
G Cyb5r1 cytochrome b5 reductase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CYB5R1 mRNA CTD PMID:19167446 NCBI chr13:45,849,017...45,855,458
Ensembl chr13:45,849,091...45,855,458 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions ISO CYP17A1 gene SNP affects the susceptibility to [Phytoestrogens results in increased abundance of 2,3-bis(3'-hydroxybenzyl)butyrolactone] CTD PMID:16702327 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased activity of CYP19A1 protein CTD PMID:15876411 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CYP2R1 mRNA CTD PMID:19167446 NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759 		JBrowse link
G Cyrib CYFIP related Rac1 interactor B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CYRIB mRNA CTD PMID:19167446 NCBI chr 7:95,633,876...95,760,588
Ensembl chr 7:95,633,876...95,697,686 		JBrowse link
G Dancr differentiation antagonizing non-protein coding RNA multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of DANCR mRNA CTD PMID:19167446 NCBI chr14:34,126,956...34,127,936 JBrowse link
G Dars2 aspartyl-tRNA synthetase 2 (mitochondrial) multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DARS2 mRNA CTD PMID:19167446 NCBI chr13:73,308,726...73,336,558
Ensembl chr13:73,308,726...73,336,934 		JBrowse link
G Dbf4 DBF4-CDC7 kinase regulatory subunit multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DBF4 mRNA CTD PMID:19167446 NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066 		JBrowse link
G Dbn1 drebrin 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of DBN1 mRNA CTD PMID:19167446 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984 		JBrowse link
G Dcaf15 DDB1 and CUL4 associated factor 15 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DCAF15 mRNA CTD PMID:19167446 NCBI chr19:24,053,925...24,061,277
Ensembl chr19:24,053,925...24,061,277 		JBrowse link
G Dcaf4 DDB1 and CUL4 associated factor 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of DCAF4 mRNA CTD PMID:19167446 NCBI chr 6:103,154,847...103,180,992
Ensembl chr 6:103,154,867...103,180,982 		JBrowse link
G Dcaf5 DDB1 and CUL4 associated factor 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of DCAF5 mRNA CTD PMID:19167446 NCBI chr 6:99,171,506...99,260,183
Ensembl chr 6:99,171,506...99,260,110 		JBrowse link
G Dclk1 doublecortin-like kinase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of DCLK1 mRNA CTD PMID:19167446 NCBI chr 2:139,417,234...139,710,956
Ensembl chr 2:139,417,163...139,710,956 		JBrowse link
G Dclre1a DNA cross-link repair 1A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DCLRE1A mRNA CTD PMID:19167446 NCBI chr 1:255,569,911...255,589,815
Ensembl chr 1:255,569,919...255,589,678 		JBrowse link
G Dclre1b DNA cross-link repair 1B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DCLRE1B mRNA CTD PMID:19167446 NCBI chr 2:191,309,909...191,318,399
Ensembl chr 2:191,309,913...191,318,423 		JBrowse link
G Ddah2 DDAH family member 2, ADMA-independent multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of DDAH2 mRNA CTD PMID:19167446 NCBI chr20:3,761,460...3,764,718
Ensembl chr20:3,761,465...3,764,511 		JBrowse link
G Ddb2 damage specific DNA binding protein 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DDB2 mRNA CTD PMID:19167446 NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631 		JBrowse link
G Ddias DNA damage-induced apoptosis suppressor multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DDIAS mRNA CTD PMID:19167446 NCBI chr 1:146,906,150...146,930,462
Ensembl chr 1:146,906,154...146,930,462 		JBrowse link
G Ddx39b DExD-box helicase 39B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DDX39B mRNA CTD PMID:19167446 NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996 		JBrowse link
G Dennd11 DENN domain containing 11 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of DENND11 mRNA CTD PMID:19167446 NCBI chr 4:69,197,161...69,266,013
Ensembl chr 4:69,198,068...69,228,821 		JBrowse link
G Depdc1 DEP domain containing 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DEPDC1 mRNA CTD PMID:19167446 NCBI chr 2:248,684,508...248,717,951
Ensembl chr 2:248,684,523...248,717,951 		JBrowse link
G Deptor DEP domain containing MTOR-interacting protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DEPTOR mRNA CTD PMID:19167446 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773 		JBrowse link
G Dera deoxyribose-phosphate aldolase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DERA mRNA CTD PMID:19167446 NCBI chr 4:170,663,689...170,742,469
Ensembl chr 4:170,663,665...170,758,865 		JBrowse link
G Dhfr dihydrofolate reductase increases expression
multiple interactions		 ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased expression of DHFR mRNA
[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DHFR mRNA		 CTD PMID:19167446 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Dhrs2 dehydrogenase/reductase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DHRS2 mRNA CTD PMID:19167446 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644 		JBrowse link
G Dhtkd1 dehydrogenase E1 and transketolase domain containing 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DHTKD1 mRNA CTD PMID:19167446 NCBI chr17:72,355,201...72,406,725
Ensembl chr17:72,355,201...72,406,723 		JBrowse link
G Diaph3 diaphanous-related formin 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DIAPH3 mRNA CTD PMID:19167446 NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975 		JBrowse link
G Dip2c disco-interacting protein 2 homolog C multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of DIP2C mRNA CTD PMID:19167446 NCBI chr17:60,647,346...61,032,467
Ensembl chr17:60,649,065...61,032,305 		JBrowse link
G Dkc1 dyskerin pseudouridine synthase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DKC1 mRNA CTD PMID:19167446
G Dlgap5 DLG associated protein 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DLGAP5 mRNA CTD PMID:19167446 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518 		JBrowse link
G Dlx2 distal-less homeobox 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of DLX2 mRNA CTD PMID:19167446 NCBI chr 3:56,370,238...56,373,581
Ensembl chr 3:56,370,483...56,373,597 		JBrowse link
G Dmxl1 Dmx-like 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of DMXL1 mRNA CTD PMID:19167446 NCBI chr18:42,993,292...43,163,457
Ensembl chr18:42,993,340...43,163,456 		JBrowse link
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of DNAJA2 mRNA CTD PMID:19167446 NCBI chr19:21,497,792...21,516,904
Ensembl chr19:21,497,729...21,516,901 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of DNAJB9 mRNA CTD PMID:19167446 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063 		JBrowse link
G Dnajc9 DnaJ heat shock protein family (Hsp40) member C9 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DNAJC9 mRNA CTD PMID:19167446 NCBI chr15:3,923,842...3,928,118
Ensembl chr15:3,923,268...3,928,118 		JBrowse link
G Dnase2 deoxyribonuclease 2, lysosomal multiple interactions
increases expression		 ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DNASE2 mRNA
2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased expression of DNASE2 mRNA		 CTD PMID:19167446 NCBI chr19:23,244,656...23,247,376
Ensembl chr19:23,244,664...23,247,376 		JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of DNM1L mRNA CTD PMID:19167446 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482 		JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DNMT1 mRNA CTD PMID:19167446 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Donson DNA replication fork stabilization factor DONSON multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DONSON mRNA CTD PMID:19167446 NCBI chr11:30,919,834...30,933,150
Ensembl chr11:30,923,239...30,932,889 		JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DSCC1 mRNA CTD PMID:19167446 NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212 		JBrowse link
G Dsn1 DSN1 component of MIS12 kinetochore complex multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DSN1 mRNA CTD PMID:19167446 NCBI chr 3:145,652,741...145,668,025
Ensembl chr 3:145,652,737...145,665,856 		JBrowse link
G Dtna dystrobrevin, alpha multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of DTNA mRNA CTD PMID:19167446 NCBI chr18:14,687,193...14,944,232
Ensembl chr18:14,587,852...14,944,261 		JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of DUSP1 mRNA CTD PMID:19167446 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dut deoxyuridine triphosphatase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DUT mRNA CTD PMID:19167446 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771 		JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of DYNC1LI1 mRNA CTD PMID:19167446 NCBI chr 8:114,376,649...114,410,297
Ensembl chr 8:114,376,662...114,410,934 		JBrowse link
G Dync2i2 dynein 2 intermediate chain 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DYNC2I2 mRNA CTD PMID:19167446 NCBI chr 3:13,306,039...13,322,121
Ensembl chr 3:13,306,039...13,322,121 		JBrowse link
G E2f2 E2F transcription factor 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of E2F2 mRNA CTD PMID:19167446 NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217 		JBrowse link
G E2f5 E2F transcription factor 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of E2F5 mRNA CTD PMID:19167446 NCBI chr 2:86,997,331...87,012,908
Ensembl chr 2:86,997,332...87,012,990 		JBrowse link
G E2f7 E2F transcription factor 7 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of E2F7 mRNA CTD PMID:19167446 NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734 		JBrowse link
G E2f8 E2F transcription factor 8 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of E2F8 mRNA CTD PMID:19167446 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of EBP mRNA CTD PMID:19167446 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826 		JBrowse link
G Ect2 epithelial cell transforming 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ECT2 mRNA CTD PMID:19167446 NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911 		JBrowse link
G Edil3 EGF like repeats and discoidin domains 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of EDIL3 mRNA CTD PMID:19167446 NCBI chr 2:19,890,396...20,405,028
Ensembl chr 2:19,890,373...20,405,008 		JBrowse link
G Eed embryonic ectoderm development multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of EED mRNA CTD PMID:19167446 NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of EEF1A1 mRNA CTD PMID:19167446 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of EFEMP1 mRNA CTD PMID:19167446 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018 		JBrowse link
G Efhd1 EF-hand domain family, member D1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of EFHD1 mRNA CTD PMID:19167446 NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917 		JBrowse link
G Efna1 ephrin A1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of EFNA1 mRNA CTD PMID:19167446 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Efnb2 ephrin B2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of EFNB2 mRNA CTD PMID:19167446 NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391 		JBrowse link
G Egr1 early growth response 1 decreases expression
multiple interactions		 ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of EGR1 mRNA
[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of EGR1 mRNA		 CTD PMID:19167446 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr3 early growth response 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of EGR3 mRNA CTD PMID:19167446 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627 		JBrowse link
G Elf5 E74 like ETS transcription factor 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ELF5 mRNA CTD PMID:19167446 NCBI chr 3:89,808,837...89,836,977
Ensembl chr 3:89,797,880...89,836,973 		JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ELK1 mRNA CTD PMID:19167446 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713 		JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ELOVL2 mRNA CTD PMID:19167446 NCBI chr17:23,544,598...23,584,855
Ensembl chr17:23,544,568...23,584,848 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ELOVL6 mRNA CTD PMID:19167446 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186 		JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ELOVL7 mRNA CTD PMID:19167446 NCBI chr 2:39,789,229...39,858,579
Ensembl chr 2:39,789,250...39,856,845 		JBrowse link
G Elp6 elongator acetyltransferase complex subunit 6 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ELP6 mRNA CTD PMID:19167446 NCBI chr 8:110,280,059...110,295,070
Ensembl chr 8:110,279,979...110,295,067 		JBrowse link
G Emc9 ER membrane protein complex subunit 9 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of EMC9 mRNA CTD PMID:19167446 NCBI chr15:29,071,881...29,076,098
Ensembl chr15:29,071,883...29,076,098 		JBrowse link
G Eme1 essential meiotic structure-specific endonuclease 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of EME1 mRNA CTD PMID:19167446 NCBI chr10:79,586,718...79,595,515
Ensembl chr10:79,586,729...79,595,435 		JBrowse link
G Enc1 ectodermal-neural cortex 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ENC1 mRNA CTD PMID:19167446 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713 		JBrowse link
G Endod1 endonuclease domain containing 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ENDOD1 mRNA CTD PMID:19167446 NCBI chr 8:11,209,113...11,238,507
Ensembl chr 8:11,211,110...11,238,892 		JBrowse link
G Enosf1 enolase superfamily member 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ENOSF1 mRNA CTD PMID:19167446 NCBI chr 9:113,275,267...113,314,842 JBrowse link
G Entrep1 endosomal transmembrane epsin interactor 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ENTREP1 mRNA CTD PMID:19167446 NCBI chr 1:221,592,500...221,646,603
Ensembl chr 1:221,592,503...221,646,758 		JBrowse link
G Epb41l5 erythrocyte membrane protein band 4.1 like 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of EPB41L5 mRNA CTD PMID:19167446 NCBI chr13:30,670,792...30,770,213
Ensembl chr13:30,669,764...30,768,360 		JBrowse link
G Epha4 Eph receptor A4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of EPHA4 mRNA CTD PMID:19167446 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139 		JBrowse link
G Eps15l1 epidermal growth factor receptor pathway substrate 15-like 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of EPS15L1 mRNA CTD PMID:19167446 NCBI chr16:17,426,345...17,501,677
Ensembl chr16:17,426,421...17,501,677 		JBrowse link
G Ercc6l ERCC excision repair 6 like, spindle assembly checkpoint helicase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ERCC6L mRNA CTD PMID:19167446 NCBI chr  X:67,245,414...67,261,222
Ensembl chr  X:67,245,414...67,280,756 		JBrowse link
G Eri2 ERI1 exoribonuclease family member 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ERI2 mRNA CTD PMID:19167446 NCBI chr 1:174,140,831...174,168,757
Ensembl chr 1:174,141,993...174,168,665 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 decreases expression
multiple interactions		 ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of ERRFI1 mRNA
[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ERRFI1 mRNA		 CTD PMID:19167446 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282 		JBrowse link
G Espl1 extra spindle pole bodies like 1, separase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ESPL1 mRNA CTD PMID:19167446 NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984 		JBrowse link
G Exo1 exonuclease 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of EXO1 mRNA CTD PMID:19167446 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654 		JBrowse link
G Exoc2 exocyst complex component 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of EXOC2 mRNA CTD PMID:19167446 NCBI chr17:33,506,289...33,698,246
Ensembl chr17:33,506,338...33,693,289 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 multiple interactions
decreases expression		 ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of EXT1 mRNA
2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of EXT1 mRNA		 CTD PMID:19167446 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of EZH2 mRNA CTD PMID:19167446 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Ezr ezrin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of EZR mRNA CTD PMID:19167446 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of F2RL1 mRNA CTD PMID:19167446 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Fam107b family with sequence similarity 107, member B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of FAM107B mRNA CTD PMID:19167446 NCBI chr17:74,478,608...74,685,027
Ensembl chr17:74,478,608...74,684,989 		JBrowse link
G Fam110b family with sequence similarity 110, member B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of FAM110B mRNA CTD PMID:19167446 NCBI chr 5:18,789,362...18,929,647
Ensembl chr 5:18,789,389...18,929,828 		JBrowse link
G Fam111a FAM111 trypsin like peptidase A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of FAM111A mRNA CTD PMID:19167446 NCBI chr 1:209,640,865...209,656,551
Ensembl chr 1:209,640,953...209,656,547 		JBrowse link
G Fam149b1 family with sequence similarity 149, member B1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of FAM149B1 mRNA CTD PMID:19167446 NCBI chr15:3,929,190...3,967,140
Ensembl chr15:3,929,190...3,966,997 		JBrowse link
G Fam43a family with sequence similarity 43, member A decreases expression
multiple interactions		 ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of FAM43A mRNA
[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of FAM43A mRNA		 CTD PMID:19167446 NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401 		JBrowse link
G Fancd2 FA complementation group D2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of FANCD2 mRNA CTD PMID:19167446 NCBI chr 4:146,679,014...146,743,422
Ensembl chr 4:146,679,179...146,743,412 		JBrowse link
G Fancg FA complementation group G multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of FANCG mRNA CTD PMID:19167446 NCBI chr 5:57,230,287...57,240,067
Ensembl chr 5:57,231,685...57,240,029 		JBrowse link
G Fanci FA complementation group I multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of FANCI mRNA CTD PMID:19167446 NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640 		JBrowse link
G Fancl FA complementation group L multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of FANCL mRNA CTD PMID:19167446 NCBI chr14:100,249,733...100,317,958
Ensembl chr14:100,248,875...100,314,255 		JBrowse link
G Fbxo38 F-box protein 38 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of FBXO38 mRNA CTD PMID:19167446 NCBI chr18:55,956,950...56,004,013
Ensembl chr18:55,956,959...56,003,961 		JBrowse link
G Fbxo5 F-box protein 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of FBXO5 mRNA CTD PMID:19167446 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437 		JBrowse link
G Fcmr Fc mu receptor multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of FCMR mRNA CTD PMID:19167446 NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of FDFT1 mRNA CTD PMID:19167446 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of FEN1 mRNA CTD PMID:19167446 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of FERMT2 mRNA CTD PMID:19167446 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811 		JBrowse link
G Fibp FGF1 intracellular binding protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of FIBP mRNA CTD PMID:19167446 NCBI chr 1:202,768,065...202,772,405
Ensembl chr 1:202,768,078...202,772,399 		JBrowse link
G Fignl1 fidgetin-like 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of FIGNL1 mRNA CTD PMID:19167446 NCBI chr14:86,368,670...86,381,728
Ensembl chr14:86,368,675...86,377,455 		JBrowse link
G Filip1l filamin A interacting protein 1-like multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of FILIP1L mRNA CTD PMID:19167446 NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415 		JBrowse link
G Firrm FIGNL1 interacting regulator of recombination and mitosis multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of FIRRM mRNA CTD PMID:19167446 NCBI chr13:76,301,914...76,345,842
Ensembl chr13:76,301,918...76,345,804 		JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of FKBP11 mRNA CTD PMID:19167446 NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303 		JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of FKBP4 mRNA CTD PMID:19167446 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833 		JBrowse link
G Flcn folliculin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of FLCN mRNA CTD PMID:19167446 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769 		JBrowse link
G Fnbp1 formin binding protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of FNBP1 mRNA CTD PMID:19167446 NCBI chr 3:14,309,067...14,424,378
Ensembl chr 3:14,309,640...14,424,881 		JBrowse link
G Fnbp1l formin binding protein 1-like multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of FNBP1L mRNA CTD PMID:19167446 NCBI chr 2:210,647,241...210,748,203
Ensembl chr 2:210,647,246...210,738,455 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of FOS mRNA CTD PMID:19167446 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Foxm1 forkhead box M1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of FOXM1 mRNA CTD PMID:19167446 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of FOXO3 mRNA CTD PMID:19167446 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Foxp2 forkhead box P2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of FOXP2 mRNA CTD PMID:19167446 NCBI chr 4:43,133,827...43,712,442
Ensembl chr 4:43,133,912...43,711,683 		JBrowse link
G Frmd6 FERM domain containing 6 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of FRMD6 mRNA CTD PMID:19167446 NCBI chr 6:89,345,983...89,419,579
Ensembl chr 6:89,346,035...89,419,579 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of FSCN1 mRNA CTD PMID:19167446 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211 		JBrowse link
G Fyco1 FYVE and coiled-coil domain autophagy adaptor 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of FYCO1 mRNA CTD PMID:19167446 NCBI chr 8:123,412,105...123,479,315
Ensembl chr 8:123,412,112...123,479,021 		JBrowse link
G G2e3 G2/M-phase specific E3 ubiquitin protein ligase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of G2E3 mRNA CTD PMID:19167446 NCBI chr 6:68,763,847...68,795,305
Ensembl chr 6:68,764,185...68,793,924 		JBrowse link
G G3bp2 G3BP stress granule assembly factor 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of G3BP2 mRNA CTD PMID:19167446 NCBI chr14:15,932,403...16,020,555
Ensembl chr14:15,987,417...16,020,548 		JBrowse link
G Gabpb2 GA binding protein transcription factor subunit beta 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GABPB2 mRNA CTD PMID:19167446 NCBI chr 2:182,755,304...182,795,368
Ensembl chr 2:182,761,359...182,795,109 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression
multiple interactions		 ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of GADD45A mRNA
[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GADD45A mRNA		 CTD PMID:19167446 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Galns galactosamine (N-acetyl)-6-sulfatase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GALNS mRNA CTD PMID:19167446 NCBI chr19:50,628,639...50,662,477
Ensembl chr19:50,628,552...50,662,246 		JBrowse link
G Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GALNT1 mRNA CTD PMID:19167446 NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245 		JBrowse link
G Galnt10 polypeptide N-acetylgalactosaminyltransferase 10 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GALNT10 mRNA CTD PMID:19167446 NCBI chr10:41,821,216...41,967,618
Ensembl chr10:41,820,158...41,967,013 		JBrowse link
G Galnt7 polypeptide N-acetylgalactosaminyltransferase 7 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GALNT7 mRNA CTD PMID:19167446 NCBI chr16:32,578,643...32,703,189
Ensembl chr16:32,578,690...32,702,690 		JBrowse link
G Ganab glucosidase II alpha subunit multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GANAB mRNA CTD PMID:19167446 NCBI chr 1:205,793,910...205,813,704
Ensembl chr 1:205,793,895...205,813,695 		JBrowse link
G Gas2l3 growth arrest-specific 2 like 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GAS2L3 mRNA CTD PMID:19167446 NCBI chr 7:23,803,578...23,836,816
Ensembl chr 7:23,806,310...23,836,411 		JBrowse link
G Gata2 GATA binding protein 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GATA2 mRNA CTD PMID:19167446 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Gbp2 guanylate binding protein 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GBP2 mRNA CTD PMID:19167446 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G Gchfr GTP cyclohydrolase I feedback regulator multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GCHFR mRNA CTD PMID:19167446 NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080 		JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GDF15 mRNA CTD PMID:19167446 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GDPD3 mRNA CTD PMID:19167446 NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063 		JBrowse link
G Gemin2 gem (nuclear organelle) associated protein 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GEMIN2 mRNA CTD PMID:19167446 NCBI chr 6:76,706,424...76,721,154
Ensembl chr 6:76,707,523...76,721,153 		JBrowse link
G Gfra1 GDNF family receptor alpha 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GFRA1 mRNA CTD PMID:19167446 NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473 		JBrowse link
G Ggct gamma-glutamyl cyclotransferase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GGCT mRNA CTD PMID:19167446 NCBI chr 4:84,122,921...84,129,327
Ensembl chr 4:84,123,118...84,129,277 		JBrowse link
G Ggh gamma-glutamyl hydrolase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GGH mRNA CTD PMID:19167446 NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787 		JBrowse link
G Gins1 GINS complex subunit 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GINS1 mRNA CTD PMID:19167446 NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936 		JBrowse link
G Gins2 GINS complex subunit 2 multiple interactions
increases expression		 ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GINS2 mRNA
2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased expression of GINS2 mRNA		 CTD PMID:19167446 NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339 		JBrowse link
G Gins3 GINS complex subunit 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GINS3 mRNA CTD PMID:19167446 NCBI chr19:9,420,085...9,428,621
Ensembl chr19:9,420,086...9,428,687 		JBrowse link
G Gins4 GINS complex subunit 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GINS4 mRNA CTD PMID:19167446 NCBI chr16:68,787,572...68,799,938
Ensembl chr16:68,767,339...68,802,273 		JBrowse link
G Gle1 GLE1 RNA export mediator multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GLE1 mRNA CTD PMID:19167446 NCBI chr 3:13,209,312...13,237,018
Ensembl chr 3:13,209,322...13,237,379 		JBrowse link
G Gmnn geminin, DNA replication inhibitor multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GMNN mRNA CTD PMID:19167446 NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054 		JBrowse link
G Gmps guanine monophosphate synthase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GMPS mRNA CTD PMID:19167446 NCBI chr 2:148,441,369...148,491,908
Ensembl chr 2:148,435,643...148,485,875 		JBrowse link
G Gnas GNAS complex locus decreases expression ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of GNAS mRNA CTD PMID:19167446 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Golga2 golgin A2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GOLGA2 mRNA CTD PMID:19167446 NCBI chr 3:15,583,862...15,604,279
Ensembl chr 3:15,584,039...15,604,279 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GOT1 mRNA CTD PMID:19167446 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gpaa1 glycosylphosphatidylinositol anchor attachment 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GPAA1 mRNA CTD PMID:19167446 NCBI chr 7:108,051,896...108,055,479
Ensembl chr 7:108,051,861...108,055,484 		JBrowse link
G Gpat4 glycerol-3-phosphate acyltransferase 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GPAT4 mRNA CTD PMID:19167446 NCBI chr16:68,819,031...68,852,903
Ensembl chr16:68,819,079...68,852,901 		JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GPRC5A mRNA CTD PMID:19167446 NCBI chr 4:167,903,542...167,922,276
Ensembl chr 4:167,903,542...167,922,260 		JBrowse link
G Gprc5c G protein-coupled receptor, class C, group 5, member C multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GPRC5C mRNA CTD PMID:19167446 NCBI chr10:99,886,900...99,908,928
Ensembl chr10:99,887,077...99,908,926 		JBrowse link
G Gpsm2 G-protein signaling modulator 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GPSM2 mRNA CTD PMID:19167446 NCBI chr 2:196,327,149...196,375,322
Ensembl chr 2:196,327,149...196,375,154 		JBrowse link
G Gramd1a GRAM domain containing 1A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GRAMD1A mRNA CTD PMID:19167446 NCBI chr 1:86,367,001...86,393,348
Ensembl chr 1:86,367,001...86,393,336 		JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GREB1 mRNA CTD PMID:19167446 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633 		JBrowse link
G Grhl3 grainyhead-like transcription factor 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GRHL3 mRNA CTD PMID:19167446 NCBI chr 5:147,774,161...147,806,291
Ensembl chr 5:147,774,160...147,806,160 		JBrowse link
G Gtf2ird1 GTF2I repeat domain containing 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GTF2IRD1 mRNA CTD PMID:19167446 NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040 		JBrowse link
G Gtse1 G-2 and S-phase expressed 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of GTSE1 mRNA CTD PMID:19167446 NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806 		JBrowse link
G Gulp1 GULP PTB domain containing engulfment adaptor 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GULP1 mRNA CTD PMID:19167446 NCBI chr 9:46,622,699...46,899,005
Ensembl chr 9:46,622,669...46,899,005 		JBrowse link
G H1f2 H1.2 linker histone, cluster member multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of H1-2 mRNA CTD PMID:19167446 NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635 		JBrowse link
G H2ac25 H2A clustered histone 25 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of H2AC25 mRNA CTD PMID:19167446 NCBI chr10:43,733,702...43,735,254
Ensembl chr10:43,733,668...43,744,874 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of H2AX mRNA CTD PMID:19167446 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G H2az1 H2A.Z variant histone 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of H2AZ1 mRNA CTD PMID:19167446 NCBI chr 2:226,355,668...226,357,984
Ensembl chr 2:226,355,708...226,358,485 		JBrowse link
G H2az2 H2A.Z variant histone 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of H2AZ2 mRNA CTD PMID:19167446 NCBI chr14:81,293,304...81,312,209
Ensembl chr14:81,293,299...81,312,144 		JBrowse link
G H2bc8 H2B clustered histone 8 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of H2BC8 mRNA CTD PMID:19167446 NCBI chr17:42,708,658...42,709,408 JBrowse link
G H2bc9 H2B clustered histone 9 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of H2BC9 mRNA CTD PMID:19167446 NCBI chr17:42,470,593...42,478,590 JBrowse link
G H3f3b H3.3 histone B decreases expression
multiple interactions		 ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of H3-3B mRNA
[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of H3-3B mRNA		 CTD PMID:19167446 NCBI chr10:101,256,484...101,258,716
Ensembl chr10:101,256,480...101,258,709 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HADH mRNA CTD PMID:19167446 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353 		JBrowse link
G Haus1 HAUS augmin-like complex, subunit 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HAUS1 mRNA CTD PMID:19167446 NCBI chr18:71,275,417...71,286,626
Ensembl chr18:71,273,537...71,286,660 		JBrowse link
G Haus4 HAUS augmin-like complex, subunit 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HAUS4 mRNA CTD PMID:19167446 NCBI chr15:27,994,530...28,006,147
Ensembl chr15:27,994,532...28,005,938 		JBrowse link
G Hebp1 heme binding protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of HEBP1 mRNA CTD PMID:19167446 NCBI chr 4:167,974,316...168,003,854
Ensembl chr 4:167,974,319...168,003,854 		JBrowse link
G Hells helicase, lymphoid specific multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HELLS mRNA CTD PMID:19167446 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844 		JBrowse link
G Helz2 helicase with zinc finger 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of HELZ2 mRNA CTD PMID:19167446 NCBI chr 3:168,338,813...168,353,219
Ensembl chr 3:168,338,813...168,353,159 		JBrowse link
G Herc1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of HERC1 mRNA CTD PMID:19167446 NCBI chr 8:66,857,169...67,070,318
Ensembl chr 8:66,856,935...67,070,312 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of HES1 mRNA CTD PMID:19167446 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hirip3 HIRA interacting protein 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HIRIP3 mRNA CTD PMID:19167446 NCBI chr 1:181,472,537...181,475,082
Ensembl chr 1:181,472,056...181,475,079 		JBrowse link
G Hist1h2af histone cluster 1 H2A family member F multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of H2AC8 mRNA CTD PMID:19167446 NCBI chr17:41,379,404...41,379,796
Ensembl chr17:41,379,404...41,379,796 		JBrowse link
G Hist1h2al1 histone cluster 1 H2A family like 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of H2AC6 mRNA CTD PMID:19167446 NCBI chr17:42,707,954...42,708,420 JBrowse link
G Hist1h2bc histone cluster 1, H2bc multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of H2BC21 mRNA CTD PMID:19167446 NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642 		JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of H2BC5 mRNA CTD PMID:19167446 NCBI chr17:42,792,887...42,793,268 JBrowse link
G Hjurp Holliday junction recognition protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HJURP mRNA CTD PMID:19167446 NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728 		JBrowse link
G Hmga1 high mobility group AT-hook 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HMGA1 mRNA CTD PMID:19167446 NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HMGB1 mRNA CTD PMID:19167446 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmgb2 high mobility group box 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HMGB2 mRNA CTD PMID:19167446 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140 		JBrowse link
G Hmgn3 high mobility group nucleosomal binding domain 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HMGN3 mRNA CTD PMID:19167446 NCBI chr 8:84,022,493...84,059,329
Ensembl chr 8:84,022,495...84,062,976 		JBrowse link
G Hmmr hyaluronan-mediated motility receptor multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HMMR mRNA CTD PMID:19167446 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060 		JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HNRNPH1 mRNA CTD PMID:19167446 NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846 		JBrowse link
G Hoxc6 homeo box C6 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HOXC6 mRNA CTD PMID:19167446 NCBI chr 7:134,138,017...134,148,899
Ensembl chr 7:134,135,502...134,148,392 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HPRT1 mRNA CTD PMID:19167446 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Hs6st2 heparan sulfate 6-O-sulfotransferase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of HS6ST2 mRNA CTD PMID:19167446 NCBI chr  X:130,966,547...131,261,629
Ensembl chr  X:130,968,385...131,261,492 		JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 decreases activity ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased activity of HSD17B1 protein CTD PMID:15876411 NCBI chr10:86,009,728...86,011,928
Ensembl chr10:86,009,728...86,011,927 		JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HSD17B6 mRNA CTD PMID:19167446 NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425 		JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HSPA4L mRNA CTD PMID:19167446 NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084 		JBrowse link
G Hyls1 HYLS1, centriolar and ciliogenesis associated multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of HYLS1 mRNA CTD PMID:19167446 NCBI chr 8:33,912,692...33,921,760
Ensembl chr 8:33,912,692...33,921,760 		JBrowse link
G Ica1 islet cell autoantigen 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ICA1 mRNA CTD PMID:19167446 NCBI chr 4:36,656,475...36,804,705
Ensembl chr 4:36,656,475...36,804,298 		JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases secretion ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased secretion of ICAM1 protein CTD PMID:29740324 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ice1 interactor of little elongation complex ELL subunit 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ICE1 mRNA CTD PMID:19167446 NCBI chr 1:32,640,372...32,682,669
Ensembl chr 1:32,640,407...32,679,898 		JBrowse link
G Icmt isoprenylcysteine carboxyl methyltransferase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ICMT mRNA CTD PMID:19167446 NCBI chr 5:162,804,368...162,811,129
Ensembl chr 5:162,804,368...162,811,128 		JBrowse link
G Id3 inhibitor of DNA binding 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ID3 mRNA CTD PMID:19167446 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349 		JBrowse link
G Ids iduronate 2-sulfatase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IDS mRNA CTD PMID:19167446 NCBI chr  X:149,025,976...149,046,641
Ensembl chr  X:149,025,976...149,046,663 		JBrowse link
G Ier2 immediate early response 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IER2 mRNA CTD PMID:19167446 NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211 		JBrowse link
G Ier5 immediate early response 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IER5 mRNA CTD PMID:19167446 NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227 		JBrowse link
G Ifi44l interferon-induced protein 44-like multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IFI44L mRNA CTD PMID:19167446 NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359 		JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IFIT2 mRNA CTD PMID:19167446 NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635 		JBrowse link
G Ifrd2 interferon-related developmental regulator 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of IFRD2 mRNA CTD PMID:19167446 NCBI chr 8:108,260,969...108,266,191
Ensembl chr 8:108,260,969...108,266,194 		JBrowse link
G Ift122 intraflagellar transport 122 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IFT122 mRNA CTD PMID:19167446 NCBI chr 4:148,905,031...148,975,458
Ensembl chr 4:148,905,046...148,975,458 		JBrowse link
G Ift20 intraflagellar transport 20 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IFT20 mRNA CTD PMID:19167446 NCBI chr10:63,432,597...63,438,125
Ensembl chr10:63,432,633...63,438,124 		JBrowse link
G Ift43 intraflagellar transport 43 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IFT43 mRNA CTD PMID:19167446 NCBI chr 6:105,729,734...105,806,257
Ensembl chr 6:105,729,792...105,806,257 		JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of IGFBP2 mRNA CTD PMID:19167446 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of IGFBP4 mRNA CTD PMID:19167446 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IGFBP5 mRNA CTD PMID:19167446 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156 		JBrowse link
G Igflr1 IGF-like family receptor 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of IGFLR1 mRNA CTD PMID:19167446 NCBI chr 1:85,818,428...85,821,032
Ensembl chr 1:85,816,326...85,821,030 		JBrowse link
G Il1b interleukin 1 beta decreases secretion ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased secretion of IL1B protein CTD PMID:29740324 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IL1R1 mRNA CTD PMID:19167446 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
G Il20 interleukin 20 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of IL20 mRNA CTD PMID:19167446 NCBI chr13:42,380,981...42,384,625
Ensembl chr13:42,380,981...42,384,625 		JBrowse link
G Ilf2 interleukin enhancer binding factor 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ILF2 mRNA CTD PMID:19167446 NCBI chr 2:175,952,174...175,971,191
Ensembl chr 2:175,952,186...175,971,337 		JBrowse link
G Ilvbl ilvB acetolactate synthase like multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ILVBL mRNA CTD PMID:19167446 NCBI chr 7:11,039,870...11,049,924
Ensembl chr 7:11,039,871...11,049,924 		JBrowse link
G Incenp inner centromere protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of INCENP mRNA CTD PMID:19167446 NCBI chr 1:206,520,655...206,550,575
Ensembl chr 1:206,523,380...206,553,265 		JBrowse link
G Inhbb inhibin subunit beta B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of INHBB mRNA CTD PMID:19167446 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832 		JBrowse link
G Ino80e INO80 complex subunit E multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of INO80E mRNA CTD PMID:19167446 NCBI chr 1:181,461,406...181,472,059
Ensembl chr 1:181,461,408...181,472,469 		JBrowse link
G Insig1 insulin induced gene 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of INSIG1 mRNA CTD PMID:19167446 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IP6K2 mRNA CTD PMID:19167446 NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166 		JBrowse link
G Iqck IQ motif containing K multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IQCK mRNA CTD PMID:19167446 NCBI chr 1:173,199,308...173,316,982
Ensembl chr 1:173,199,316...173,316,984 		JBrowse link
G Iqgap3 IQ motif containing GTPase activating protein 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of IQGAP3 mRNA CTD PMID:19167446 NCBI chr 2:173,542,151...173,583,956
Ensembl chr 2:173,542,110...173,583,956 		JBrowse link
G Irf6 interferon regulatory factor 6 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IRF6 mRNA CTD PMID:19167446 NCBI chr13:104,672,179...104,691,386
Ensembl chr13:104,672,179...104,691,386 		JBrowse link
G Irf9 interferon regulatory factor 9 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IRF9 mRNA CTD PMID:19167446 NCBI chr15:29,095,474...29,101,924
Ensembl chr15:29,095,789...29,101,236 		JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IRS2 mRNA CTD PMID:19167446 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482 		JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ISYNA1 mRNA CTD PMID:19167446 NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979 		JBrowse link
G Itga2 integrin subunit alpha 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ITGA2 mRNA CTD PMID:19167446 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481 		JBrowse link
G Itgae integrin subunit alpha E multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ITGAE mRNA CTD PMID:19167446 NCBI chr10:57,704,813...57,764,093
Ensembl chr10:57,591,753...57,764,093
Ensembl chr10:57,591,753...57,764,093 		JBrowse link
G Itgal integrin subunit alpha L decreases secretion ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased secretion of ITGAL protein CTD PMID:29740324 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732 		JBrowse link
G Itgb2 integrin subunit beta 2 decreases secretion ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased secretion of ITGB2 protein CTD PMID:29740324 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Itgb3bp integrin subunit beta 3 binding protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ITGB3BP mRNA CTD PMID:19167446 NCBI chr 5:114,460,217...114,525,538
Ensembl chr 5:114,460,221...114,525,704 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ITPR1 mRNA CTD PMID:19167446 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of JAG1 mRNA CTD PMID:19167446 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Jmy junction mediating and regulatory protein, p53 cofactor multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of JMY mRNA CTD PMID:19167446 NCBI chr 2:24,662,104...24,730,955
Ensembl chr 2:24,668,854...24,731,006 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of JUN mRNA CTD PMID:19167446 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of JUNB mRNA CTD PMID:19167446 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Kdm4b lysine demethylase 4B decreases expression ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of KDM4B mRNA CTD PMID:19167446 NCBI chr 9:1,158,737...1,237,233
Ensembl chr 9:1,158,752...1,236,543 		JBrowse link
G Kdm5a lysine demethylase 5A decreases expression ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of KDM5A mRNA CTD PMID:19167446 NCBI chr 4:153,565,909...153,643,912
Ensembl chr 4:153,565,846...153,642,422 		JBrowse link
G Kdm5b lysine demethylase 5B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of KDM5B mRNA CTD PMID:19167446 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872 		JBrowse link
G Kdr kinase insert domain receptor multiple interactions ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone inhibits the reaction [Estradiol results in increased expression of KDR protein] CTD PMID:17289903 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Kidins220 kinase D-interacting substrate 220 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of KIDINS220 mRNA CTD PMID:19167446 NCBI chr 6:41,618,207...41,706,990
Ensembl chr 6:41,618,294...41,703,256 		JBrowse link
G Kif11 kinesin family member 11 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of KIF11 mRNA CTD PMID:19167446 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766 		JBrowse link
G Kif14 kinesin family member 14 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of KIF14 mRNA CTD PMID:19167446 NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164 		JBrowse link
G Kif18a kinesin family member 18A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of KIF18A mRNA CTD PMID:19167446 NCBI chr 3:95,764,388...95,824,756
Ensembl chr 3:95,764,388...95,824,582 		JBrowse link
G Kif20a kinesin family member 20A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of KIF20A mRNA CTD PMID:19167446 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780 		JBrowse link
G Kif2c kinesin family member 2C multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of KIF2C mRNA CTD PMID:19167446 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637 		JBrowse link
G Kif5c kinesin family member 5C multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of KIF5C mRNA CTD PMID:19167446 NCBI chr 3:34,032,082...34,185,597
Ensembl chr 3:34,032,105...34,182,413 		JBrowse link
G Kifc1 kinesin family member C1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of KIFC1 mRNA CTD PMID:19167446 NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105 		JBrowse link
G Klf12 KLF transcription factor 12 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of KLF12 mRNA CTD PMID:19167446 NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056 		JBrowse link
G Klf6 KLF transcription factor 6 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of KLF6 mRNA CTD PMID:19167446 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570 		JBrowse link
G Klf9 KLF transcription factor 9 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of KLF9 mRNA CTD PMID:19167446 NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037 		JBrowse link
G Klhdc3 kelch domain containing 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of KLHDC3 mRNA CTD PMID:19167446 NCBI chr 9:14,302,345...14,308,736
Ensembl chr 9:14,302,354...14,308,736 		JBrowse link
G Klhl24 kelch-like family member 24 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of KLHL24 mRNA CTD PMID:19167446 NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636 		JBrowse link
G Klhl5 kelch-like family member 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of KLHL5 mRNA CTD PMID:19167446 NCBI chr14:43,144,254...43,206,192
Ensembl chr14:43,144,257...43,184,238 		JBrowse link
G Kmt2e lysine methyltransferase 2E multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of KMT2E mRNA CTD PMID:19167446 NCBI chr 4:11,658,218...11,727,373
Ensembl chr 4:11,658,979...11,727,373 		JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of KNSTRN mRNA CTD PMID:19167446 NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715 		JBrowse link
G Kpna4 karyopherin subunit alpha 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of KPNA4 mRNA CTD PMID:19167446 NCBI chr 2:153,319,380...153,381,085
Ensembl chr 2:153,324,273...153,381,081 		JBrowse link
G Krt80 keratin 80 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of KRT80 mRNA CTD PMID:19167446 NCBI chr 7:132,463,216...132,485,134
Ensembl chr 7:132,463,218...132,485,508 		JBrowse link
G L1cam L1 cell adhesion molecule multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of L1CAM mRNA CTD PMID:19167446 NCBI chr  X:151,597,270...151,623,776
Ensembl chr  X:151,597,277...151,623,857 		JBrowse link
G L2hgdh L-2-hydroxyglutarate dehydrogenase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of L2HGDH mRNA CTD PMID:19167446 NCBI chr 6:88,164,429...88,205,585
Ensembl chr 6:88,164,440...88,205,578 		JBrowse link
G Lage3 L antigen family, member 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of LAGE3 mRNA CTD PMID:19167446 NCBI chr  X:152,138,209...152,139,632
Ensembl chr  X:152,138,218...152,139,632 		JBrowse link
G Larp6 La ribonucleoprotein 6, translational regulator multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of LARP6 mRNA CTD PMID:19167446 NCBI chr 8:61,183,744...61,205,548
Ensembl chr 8:61,184,116...61,205,535 		JBrowse link
G Lcmt2 leucine carboxyl methyltransferase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of LCMT2 mRNA CTD PMID:19167446 NCBI chr 3:108,099,960...108,102,084
Ensembl chr 3:108,099,961...108,102,084 		JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of LDLR mRNA CTD PMID:19167446 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lepr leptin receptor multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of LEPR mRNA CTD PMID:19167446 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Lgals1 galectin 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of LGALS1 mRNA CTD PMID:19167446 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345 		JBrowse link
G Lig1 DNA ligase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of LIG1 mRNA CTD PMID:19167446 NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413 		JBrowse link
G Lmnb1 lamin B1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of LMNB1 mRNA CTD PMID:19167446 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502 		JBrowse link
G Lmnb2 lamin B2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of LMNB2 mRNA CTD PMID:19167446 NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665 		JBrowse link
G Lrig1 leucine-rich repeats and immunoglobulin-like domains 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of LRIG1 mRNA CTD PMID:19167446 NCBI chr 4:127,130,899...127,230,956
Ensembl chr 4:127,130,898...127,231,513 		JBrowse link
G Lrr1 leucine rich repeat protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of LRR1 mRNA CTD PMID:19167446 NCBI chr 6:87,643,195...87,651,894
Ensembl chr 6:87,643,217...87,651,894 		JBrowse link
G Lsm2 LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of LSM2 mRNA CTD PMID:19167446 NCBI chr20:3,843,467...3,847,217
Ensembl chr20:3,843,466...3,847,266 		JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MAD2L1 mRNA CTD PMID:19167446 NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470 		JBrowse link
G Maff MAF bZIP transcription factor F multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MAFF mRNA CTD PMID:19167446 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851 		JBrowse link
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MAGI1 mRNA CTD PMID:19167446 NCBI chr 4:126,205,663...126,811,354
Ensembl chr 4:126,206,816...126,811,691 		JBrowse link
G Map1b microtubule-associated protein 1B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MAP1B mRNA CTD PMID:19167446 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MAP4K4 mRNA CTD PMID:19167446 NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:29740324 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mast4 microtubule associated serine/threonine kinase family member 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MAST4 mRNA CTD PMID:19167446 NCBI chr 2:33,893,241...34,483,682
Ensembl chr 2:33,894,436...34,483,723 		JBrowse link
G Mastl microtubule associated serine/threonine kinase-like multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MASTL mRNA CTD PMID:19167446 NCBI chr17:85,250,512...85,287,479
Ensembl chr17:85,251,997...85,287,353 		JBrowse link
G Matn3 matrilin 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MATN3 mRNA CTD PMID:19167446 NCBI chr 6:31,748,517...31,768,564
Ensembl chr 6:31,748,474...31,768,101 		JBrowse link
G Maz MYC associated zinc finger protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MAZ mRNA CTD PMID:19167446 NCBI chr 1:181,629,742...181,635,193
Ensembl chr 1:181,629,729...181,650,408 		JBrowse link
G Mb21d2 Mab-21 domain containing 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MB21D2 mRNA CTD PMID:19167446 NCBI chr11:71,825,748...71,924,770
Ensembl chr11:71,825,748...71,924,769 		JBrowse link
G Mcam melanoma cell adhesion molecule multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MCAM mRNA CTD PMID:19167446 NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571 		JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor multiple interactions
increases expression		 ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MCM10 mRNA
2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased expression of MCM10 mRNA		 CTD PMID:19167446 NCBI chr17:73,263,788...73,288,346
Ensembl chr17:73,266,095...73,287,364 		JBrowse link
G Mcm2 minichromosome maintenance complex component 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MCM2 mRNA CTD PMID:19167446 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847 		JBrowse link
G Mcm3 minichromosome maintenance complex component 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MCM3 mRNA CTD PMID:19167446 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314 		JBrowse link
G Mcm4 minichromosome maintenance complex component 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MCM4 mRNA CTD PMID:19167446 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144 		JBrowse link
G Mcm5 minichromosome maintenance complex component 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MCM5 mRNA CTD PMID:19167446 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389 		JBrowse link
G Mcm6 minichromosome maintenance complex component 6 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MCM6 mRNA CTD PMID:19167446 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960 		JBrowse link
G Mcm7 minichromosome maintenance complex component 7 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MCM7 mRNA CTD PMID:19167446 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063 		JBrowse link
G Mcm8 minichromosome maintenance 8 homologous recombination repair factor multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MCM8 mRNA CTD PMID:19167446 NCBI chr 3:120,086,741...120,117,008
Ensembl chr 3:120,086,763...120,117,008 		JBrowse link
G Mcub mitochondrial calcium uniporter dominant negative subunit beta multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MCUB mRNA CTD PMID:19167446 NCBI chr 2:218,479,301...218,549,594
Ensembl chr 2:218,479,301...218,549,593 		JBrowse link
G Mdc1 mediator of DNA damage checkpoint 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MDC1 mRNA CTD PMID:19167446 NCBI chr20:2,893,693...2,912,394
Ensembl chr20:2,895,505...2,910,240 		JBrowse link
G Mea1 male-enhanced antigen 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MEA1 mRNA CTD PMID:19167446 NCBI chr 9:14,300,283...14,304,130
Ensembl chr 9:14,293,446...14,302,060 		JBrowse link
G Meaf6 MYST/Esa1-associated factor 6 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MEAF6 mRNA CTD PMID:19167446 NCBI chr 5:137,344,681...137,369,703
Ensembl chr 5:137,344,380...137,370,014 		JBrowse link
G Mef2a myocyte enhancer factor 2a multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MEF2A mRNA CTD PMID:19167446 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948 		JBrowse link
G Melk maternal embryonic leucine zipper kinase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MELK mRNA CTD PMID:19167446 NCBI chr 5:58,540,393...58,600,562
Ensembl chr 5:58,540,449...58,600,937 		JBrowse link
G Mepce methylphosphate capping enzyme multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MEPCE mRNA CTD PMID:19167446 NCBI chr12:18,911,796...18,916,515
Ensembl chr12:18,911,796...18,916,514 		JBrowse link
G Metap2 methionyl aminopeptidase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of METAP2 mRNA CTD PMID:19167446 NCBI chr 7:28,412,429...28,440,458
Ensembl chr 7:28,411,608...28,440,434 		JBrowse link
G Mgat4b alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MGAT4B mRNA CTD PMID:19167446 NCBI chr10:34,548,918...34,559,229
Ensembl chr10:34,549,433...34,559,229 		JBrowse link
G Mgll monoglyceride lipase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MGLL mRNA CTD PMID:19167446 NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179 		JBrowse link
G Mgp matrix Gla protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MGP mRNA CTD PMID:19167446 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667 		JBrowse link
G Mir21 microRNA 21 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MIR21 mRNA CTD PMID:19167446 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mis18bp1 MIS18 binding protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MIS18BP1 mRNA CTD PMID:19167446 NCBI chr 6:83,182,497...83,231,978
Ensembl chr 6:83,182,499...83,231,383 		JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MKI67 mRNA CTD PMID:19167446 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MKNK2 mRNA CTD PMID:19167446 NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827 		JBrowse link
G Mlh1 mutL homolog 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MLH1 mRNA CTD PMID:19167446 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Moap1 modulator of apoptosis 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MOAP1 mRNA CTD PMID:19167446 NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:121,882,366...121,898,643 		JBrowse link
G Mphosph9 M-phase phosphoprotein 9 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MPHOSPH9 mRNA CTD PMID:19167446 NCBI chr12:32,275,449...32,346,097
Ensembl chr12:32,275,558...32,342,392 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MRE11 mRNA CTD PMID:19167446 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Mrm2 mitochondrial rRNA methyltransferase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MRM2 mRNA CTD PMID:19167446 NCBI chr12:14,309,556...14,314,759
Ensembl chr12:14,251,941...14,314,118 		JBrowse link
G Mrpl37 mitochondrial ribosomal protein L37 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MRPL37 mRNA CTD PMID:19167446 NCBI chr 5:121,827,892...121,846,187
Ensembl chr 5:121,829,111...121,846,176 		JBrowse link
G Mrps26 mitochondrial ribosomal protein S26 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MRPS26 mRNA CTD PMID:19167446 NCBI chr 3:117,769,220...117,770,883
Ensembl chr 3:117,769,100...117,770,885 		JBrowse link
G Mrps27 mitochondrial ribosomal protein S27 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MRPS27 mRNA CTD PMID:19167446 NCBI chr 2:30,740,007...30,808,577
Ensembl chr 2:30,740,033...30,808,577 		JBrowse link
G Msh6 mutS homolog 6 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MSH6 mRNA CTD PMID:19167446 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956 		JBrowse link
G Mtcp1 mature T-cell proliferation 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MTCP1 mRNA CTD PMID:19167446 NCBI chr18:126,189...130,123 JBrowse link
G Mtfp1 mitochondrial fission process 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MTFP1 mRNA CTD PMID:19167446 NCBI chr14:78,968,434...78,972,274
Ensembl chr14:78,968,442...78,972,274 		JBrowse link
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MTHFD1 mRNA CTD PMID:19167446 NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372 		JBrowse link
G Mtmr4 myotubularin related protein 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MTMR4 mRNA CTD PMID:19167446 NCBI chr10:72,393,411...72,416,342
Ensembl chr10:72,392,551...72,416,342 		JBrowse link
G Mtus1 microtubule associated scaffold protein 1 multiple interactions
decreases expression		 ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MTUS1 mRNA
2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of MTUS1 mRNA		 CTD PMID:19167446 NCBI chr16:51,202,497...51,347,794
Ensembl chr16:51,253,562...51,347,793 		JBrowse link
G Mvp major vault protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MVP mRNA CTD PMID:19167446 NCBI chr 1:181,594,734...181,622,336
Ensembl chr 1:181,594,734...181,622,380 		JBrowse link
G Mxd4 Max dimerization protein 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MXD4 mRNA CTD PMID:19167446 NCBI chr14:76,562,105...76,576,224
Ensembl chr14:76,561,774...76,576,221 		JBrowse link
G Myb MYB proto-oncogene, transcription factor multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MYB mRNA CTD PMID:19167446 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057 		JBrowse link
G Mybl2 MYB proto-oncogene like 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MYBL2 mRNA CTD PMID:19167446 NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708 		JBrowse link
G Mycbp Myc binding protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MYCBP mRNA CTD PMID:19167446 NCBI chr 5:136,135,955...136,143,163
Ensembl chr 5:136,135,931...136,145,616 		JBrowse link
G Mylip myosin regulatory light chain interacting protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MYLIP mRNA CTD PMID:19167446 NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295 		JBrowse link
G Myo1b myosin Ib multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MYO1B mRNA CTD PMID:19167446 NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798 		JBrowse link
G Myo5a myosin VA multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MYO5A mRNA CTD PMID:19167446 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918 		JBrowse link
G Myo5b myosin Vb multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MYO5B mRNA CTD PMID:19167446 NCBI chr18:68,038,759...68,341,568
Ensembl chr18:68,038,759...68,338,745 		JBrowse link
G Myo6 myosin VI multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of MYO6 mRNA CTD PMID:19167446 NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292 		JBrowse link
G Mzt1 mitotic spindle organizing protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MZT1 mRNA CTD PMID:19167446 NCBI chr15:75,787,281...75,797,589
Ensembl chr15:75,786,994...75,797,589 		JBrowse link
G N4bp1 Nedd4 binding protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of N4BP1 mRNA CTD PMID:19167446 NCBI chr19:20,222,811...20,273,570
Ensembl chr19:20,222,776...20,273,570 		JBrowse link
G Naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NAA50 mRNA CTD PMID:19167446 NCBI chr11:56,538,366...56,560,842
Ensembl chr11:56,538,366...56,560,842 		JBrowse link
G Nanos1 nanos C2HC-type zinc finger 1 decreases expression
multiple interactions		 ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of NANOS1 mRNA
[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NANOS1 mRNA		 CTD PMID:19167446 NCBI chr 1:259,897,663...259,901,561
Ensembl chr 1:259,897,939...259,898,730 		JBrowse link
G Nasp nuclear autoantigenic sperm protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NASP mRNA CTD PMID:19167446 NCBI chr 5:130,057,363...130,083,003
Ensembl chr 5:130,057,363...130,082,928 		JBrowse link
G Nbea neurobeachin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NBEA mRNA CTD PMID:19167446 NCBI chr 2:139,780,021...140,338,639
Ensembl chr 2:139,780,021...140,340,584 		JBrowse link
G Nbeal1 neurobeachin-like 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NBEAL1 mRNA CTD PMID:19167446 NCBI chr 9:61,575,154...61,743,896
Ensembl chr 9:61,575,356...61,736,750 		JBrowse link
G Ncapg non-SMC condensin I complex, subunit G multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NCAPG mRNA CTD PMID:19167446 NCBI chr14:65,403,930...65,432,902
Ensembl chr14:65,404,163...65,432,902 		JBrowse link
G Ncapg2 non-SMC condensin II complex, subunit G2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NCAPG2 mRNA CTD PMID:19167446 NCBI chr 6:137,342,449...137,418,083
Ensembl chr 6:137,342,943...137,415,159 		JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NCOA1 mRNA CTD PMID:19167446 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664 		JBrowse link
G Ncoa7 nuclear receptor coactivator 7 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NCOA7 mRNA CTD PMID:19167446 NCBI chr 1:26,856,228...27,016,950
Ensembl chr 1:26,856,530...27,015,871 		JBrowse link
G Ndc1 NDC1 transmembrane nucleoporin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NDC1 mRNA CTD PMID:19167446 NCBI chr 5:122,155,992...122,202,295
Ensembl chr 5:122,155,967...122,202,291 		JBrowse link
G Ndc80 NDC80 kinetochore complex component multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NDC80 mRNA CTD PMID:19167446 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924 		JBrowse link
G Nde1 nudE neurodevelopment protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NDE1 mRNA CTD PMID:19167446 NCBI chr10:839,788...883,946
Ensembl chr10:839,788...883,869 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NDFIP1 mRNA CTD PMID:19167446 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311 		JBrowse link
G Nebl nebulette multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NEBL mRNA CTD PMID:19167446 NCBI chr17:80,113,891...80,466,331
Ensembl chr17:80,118,543...80,466,210 		JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NEDD4L mRNA CTD PMID:19167446 NCBI chr18:58,393,759...58,726,709
Ensembl chr18:58,393,509...58,723,137 		JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NEDD9 mRNA CTD PMID:19167446 NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019 		JBrowse link
G Neil3 nei-like DNA glycosylase 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NEIL3 mRNA CTD PMID:19167446 NCBI chr16:38,359,305...38,418,528
Ensembl chr16:38,359,371...38,418,527 		JBrowse link
G Neurl1b neuralized E3 ubiquitin protein ligase 1B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NEURL1B mRNA CTD PMID:19167446 NCBI chr10:16,754,002...16,785,049
Ensembl chr10:16,757,208...16,785,119 		JBrowse link
G Nfatc2ip nuclear factor of activated T-cells 2 interacting protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NFATC2IP mRNA CTD PMID:19167446 NCBI chr 1:180,954,834...180,971,847
Ensembl chr 1:180,955,043...180,971,747 		JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NFIL3 mRNA CTD PMID:19167446 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858 		JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NHERF1 mRNA CTD PMID:19167446 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598 		JBrowse link
G Ninl ninein-like multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NINL mRNA CTD PMID:19167446 NCBI chr 3:139,748,353...139,814,683
Ensembl chr 3:139,748,355...139,814,622 		JBrowse link
G Nmt2 N-myristoyltransferase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NMT2 mRNA CTD PMID:19167446 NCBI chr17:74,917,833...74,964,788
Ensembl chr17:74,917,833...74,961,080 		JBrowse link
G Nmu neuromedin U multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NMU mRNA CTD PMID:19167446 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192 		JBrowse link
G Nom1 nucleolar protein with MIF4G domain 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NOM1 mRNA CTD PMID:19167446 NCBI chr 4:5,891,220...5,910,741
Ensembl chr 4:5,892,909...5,909,709 		JBrowse link
G Npas3 neuronal PAS domain protein 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NPAS3 mRNA CTD PMID:19167446 NCBI chr 6:70,702,773...71,527,928
Ensembl chr 6:70,703,170...71,524,884 		JBrowse link
G Npepps aminopeptidase puromycin sensitive multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NPEPPS mRNA CTD PMID:19167446 NCBI chr10:82,191,454...82,273,967
Ensembl chr10:82,191,456...82,273,967 		JBrowse link
G Nphp3 nephrocystin 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NPHP3 mRNA CTD PMID:19167446 NCBI chr 8:104,621,908...104,662,383
Ensembl chr 8:104,621,864...104,662,383 		JBrowse link
G Npnt nephronectin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NPNT mRNA CTD PMID:19167446 NCBI chr 2:221,391,151...221,459,527
Ensembl chr 2:221,391,153...221,459,401 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NPY1R mRNA CTD PMID:19167446 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NQO1 mRNA CTD PMID:19167446 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NQO2 mRNA CTD PMID:19167446 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased activity of NR1I2 protein CTD PMID:15885729 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr2f6 nuclear receptor subfamily 2, group F, member 6 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NR2F6 mRNA CTD PMID:19167446 NCBI chr16:18,046,012...18,053,914
Ensembl chr16:18,046,013...18,053,459 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NR4A2 mRNA CTD PMID:19167446 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Nrcam neuronal cell adhesion molecule multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NRCAM mRNA CTD PMID:19167446 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992 		JBrowse link
G Nrm nurim multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NRM mRNA CTD PMID:19167446 NCBI chr20:2,888,321...2,892,804
Ensembl chr20:2,877,567...2,891,802 		JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NSD2 mRNA CTD PMID:19167446 NCBI chr14:76,833,179...76,911,304
Ensembl chr14:76,835,637...76,913,641 		JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NT5E mRNA CTD PMID:19167446 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881 		JBrowse link
G Ntn4 netrin 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NTN4 mRNA CTD PMID:19167446 NCBI chr 7:28,186,611...28,300,390
Ensembl chr 7:28,186,611...28,300,390 		JBrowse link
G Nuak1 NUAK family kinase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of NUAK1 mRNA CTD PMID:19167446 NCBI chr 7:19,330,034...19,401,918
Ensembl chr 7:19,329,933...19,401,913 		JBrowse link
G Nudt1 nudix hydrolase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NUDT1 mRNA CTD PMID:19167446 NCBI chr12:14,302,514...14,309,559
Ensembl chr12:14,302,694...14,305,826 		JBrowse link
G Nup107 nucleoporin 107 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NUP107 mRNA CTD PMID:19167446 NCBI chr 7:53,353,740...53,398,345
Ensembl chr 7:53,353,743...53,398,370 		JBrowse link
G Nup155 nucleoporin 155 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NUP155 mRNA CTD PMID:19167446 NCBI chr 2:57,201,310...57,252,918
Ensembl chr 2:57,201,272...57,254,148 		JBrowse link
G Nup210 nucleoporin 210 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NUP210 mRNA CTD PMID:19167446 NCBI chr 4:123,511,558...123,609,874
Ensembl chr 4:123,511,559...123,609,874 		JBrowse link
G Nup62cl nucleoporin 62 C-terminal like multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NUP62CL mRNA CTD PMID:19167446 NCBI chr  X:103,668,458...103,724,957
Ensembl chr  X:103,668,455...103,724,081 		JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of NUSAP1 mRNA CTD PMID:19167446 NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624 		JBrowse link
G Oaz2 ornithine decarboxylase antizyme 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of OAZ2 mRNA CTD PMID:19167446 NCBI chr 8:66,199,694...66,213,513
Ensembl chr 8:66,199,706...66,231,453 		JBrowse link
G Odf2 outer dense fiber of sperm tails 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ODF2 mRNA CTD PMID:19167446 NCBI chr 3:13,160,981...13,207,223
Ensembl chr 3:13,161,494...13,206,985 		JBrowse link
G Oip5 Opa interacting protein 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of OIP5 mRNA CTD PMID:19167446 NCBI chr 3:106,593,746...106,603,281
Ensembl chr 3:106,593,760...106,603,250 		JBrowse link
G Olfm1 olfactomedin 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of OLFM1 mRNA CTD PMID:19167446 NCBI chr 3:11,520,522...11,558,240
Ensembl chr 3:11,520,729...11,558,239 		JBrowse link
G Optn optineurin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of OPTN mRNA CTD PMID:19167446 NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251 		JBrowse link
G Orc1 origin recognition complex, subunit 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ORC1 mRNA CTD PMID:19167446 NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375 		JBrowse link
G Orc6 origin recognition complex, subunit 6 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ORC6 mRNA CTD PMID:19167446 NCBI chr19:21,757,867...21,765,638
Ensembl chr19:21,757,866...21,765,662 		JBrowse link
G Osbpl2 oxysterol binding protein-like 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of OSBPL2 mRNA CTD PMID:19167446 NCBI chr 3:167,210,945...167,256,219
Ensembl chr 3:167,210,832...167,256,219 		JBrowse link
G Oser1 oxidative stress responsive serine-rich 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of OSER1 mRNA CTD PMID:19167446 NCBI chr 3:152,066,975...152,085,180
Ensembl chr 3:152,066,975...152,085,149 		JBrowse link
G Otud1 OTU deubiquitinase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of OTUD1 mRNA CTD PMID:19167446 NCBI chr17:82,259,920...82,262,770
Ensembl chr17:82,259,840...82,262,995 		JBrowse link
G Oxct1 3-oxoacid CoA transferase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of OXCT1 mRNA CTD PMID:19167446 NCBI chr 2:53,236,370...53,384,715
Ensembl chr 2:53,236,368...53,384,714 		JBrowse link
G Oxtr oxytocin receptor multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of OXTR mRNA CTD PMID:19167446 NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674 		JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of P4HB mRNA CTD PMID:19167446 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500 		JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PAICS mRNA CTD PMID:19167446 NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635 		JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PAPSS2 mRNA CTD PMID:19167446 NCBI chr 1:230,454,314...230,539,332
Ensembl chr 1:230,454,426...230,539,331 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PARP1 mRNA CTD PMID:19167446 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PARP2 mRNA CTD PMID:19167446 NCBI chr15:24,034,069...24,044,340
Ensembl chr15:24,034,106...24,044,338 		JBrowse link
G Parpbp PARP1 binding protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PARPBP mRNA CTD PMID:19167446 NCBI chr 7:22,511,427...22,580,834
Ensembl chr 7:22,511,427...22,573,695 		JBrowse link
G Parva parvin, alpha multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PARVA mRNA CTD PMID:19167446 NCBI chr 1:166,547,142...166,704,958
Ensembl chr 1:166,547,132...166,704,950 		JBrowse link
G Pawr pro-apoptotic WT1 regulator multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PAWR mRNA CTD PMID:19167446 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
G Pbk PDZ binding kinase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PBK mRNA CTD PMID:19167446 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PCK2 mRNA CTD PMID:19167446 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283 		JBrowse link
G Pclaf PCNA clamp associated factor multiple interactions
increases expression		 ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PCLAF mRNA
2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased expression of PCLAF mRNA		 CTD PMID:19167446 NCBI chr 8:66,420,606...66,432,994
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994 		JBrowse link
G Pcmtd1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PCMTD1 mRNA CTD PMID:19167446 NCBI chr 5:12,284,711...12,355,680
Ensembl chr 5:12,284,711...12,354,899 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PCNA mRNA CTD PMID:19167446 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pcnt pericentrin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PCNT mRNA CTD PMID:19167446 NCBI chr20:12,190,597...12,278,723
Ensembl chr20:12,191,648...12,278,710 		JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PCSK6 mRNA CTD PMID:19167446 NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596 		JBrowse link
G Pdcd4 programmed cell death 4 increases expression ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased expression of PDCD4 mRNA CTD PMID:19167446 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275 		JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PDCD6IP mRNA CTD PMID:19167446 NCBI chr 8:113,590,998...113,646,795
Ensembl chr 8:113,590,998...113,646,773 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PDIA3 mRNA CTD PMID:19167446 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236 		JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PDIA6 mRNA CTD PMID:19167446 NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613 		JBrowse link
G Pdlim1 PDZ and LIM domain 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PDLIM1 mRNA CTD PMID:19167446 NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076 		JBrowse link
G Pdzk1 PDZ domain containing 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PDZK1 mRNA CTD PMID:19167446 NCBI chr 2:184,376,161...184,407,514
Ensembl chr 2:184,376,161...184,407,514 		JBrowse link
G Pfkl phosphofructokinase, liver type multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PFKL mRNA CTD PMID:19167446 NCBI chr20:10,664,285...10,686,324
Ensembl chr20:10,664,272...10,686,315 		JBrowse link
G Pggt1b protein geranylgeranyltransferase type I subunit beta multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PGGT1B mRNA CTD PMID:19167446 NCBI chr18:38,952,147...38,995,656
Ensembl chr18:38,952,914...38,995,503 		JBrowse link
G Pgm2l1 phosphoglucomutase 2-like 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PGM2L1 mRNA CTD PMID:19167446 NCBI chr 1:154,571,410...154,620,901
Ensembl chr 1:154,571,766...154,620,902 		JBrowse link
G Pgm3 phosphoglucomutase 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PGM3 mRNA CTD PMID:19167446 NCBI chr 8:87,518,317...87,536,021
Ensembl chr 8:87,517,701...87,536,022 		JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PGRMC1 mRNA CTD PMID:19167446 NCBI chr  X:115,832,865...115,841,060
Ensembl chr  X:115,832,884...115,888,682 		JBrowse link
G Pgrmc2 progesterone receptor membrane component 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PGRMC2 mRNA CTD PMID:19167446 NCBI chr 2:124,068,257...124,084,155
Ensembl chr 2:124,068,260...124,084,155 		JBrowse link
G Phactr2 phosphatase and actin regulator 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PHACTR2 mRNA CTD PMID:19167446 NCBI chr 1:7,591,254...7,860,431
Ensembl chr 1:7,597,927...7,860,289 		JBrowse link
G Phf19 PHD finger protein 19 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PHF19 mRNA CTD PMID:19167446 NCBI chr 3:18,175,281...18,197,289
Ensembl chr 3:18,175,282...18,196,405 		JBrowse link
G Phf20l1 PHD finger protein 20-like 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PHF20L1 mRNA CTD PMID:19167446 NCBI chr 7:98,330,580...98,396,526
Ensembl chr 7:98,330,580...98,396,526 		JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PHLDA2 mRNA CTD PMID:19167446 NCBI chr 1:198,696,897...198,699,292
Ensembl chr 1:198,696,897...198,697,836 		JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PHLDB2 mRNA CTD PMID:19167446 NCBI chr11:54,859,173...55,078,212
Ensembl chr11:54,859,135...55,078,467 		JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PIK3C3 mRNA CTD PMID:19167446 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048 		JBrowse link
G Pimreg PICALM interacting mitotic regulator multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PIMREG mRNA CTD PMID:19167446 NCBI chr10:56,669,603...56,674,540
Ensembl chr10:56,669,675...56,674,791 		JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PKIB mRNA CTD PMID:19167446 NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187 		JBrowse link
G Pkm pyruvate kinase M1/2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PKM mRNA CTD PMID:19167446 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599 		JBrowse link
G Pkmyt1 protein kinase, membrane associated tyrosine/threonine 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PKMYT1 mRNA CTD PMID:19167446 NCBI chr10:12,748,221...12,758,995
Ensembl chr10:12,748,237...12,758,995 		JBrowse link
G Plcxd1 phosphatidylinositol-specific phospholipase C, X domain containing 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PLCXD1 mRNA CTD PMID:19167446 NCBI chr12:46,578,917...46,582,181
Ensembl chr12:46,579,225...46,582,392 		JBrowse link
G Plekha5 pleckstrin homology domain containing A5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PLEKHA5 mRNA CTD PMID:19167446 NCBI chr 4:173,333,891...173,503,546
Ensembl chr 4:173,334,055...173,503,546 		JBrowse link
G Plekhb2 pleckstrin homology domain containing B2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PLEKHB2 mRNA CTD PMID:19167446 NCBI chr 9:37,049,580...37,082,231
Ensembl chr 9:37,038,751...37,082,231 		JBrowse link
G Plk1 polo-like kinase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PLK1 mRNA CTD PMID:19167446 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400 		JBrowse link
G Plk4 polo-like kinase 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PLK4 mRNA CTD PMID:19167446 NCBI chr 2:123,802,527...123,820,942
Ensembl chr 2:123,802,512...123,820,942 		JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PLOD2 mRNA CTD PMID:19167446 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255 		JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PMEPA1 mRNA CTD PMID:19167446 NCBI chr 3:162,011,884...162,060,343
Ensembl chr 3:162,012,751...162,060,454 		JBrowse link
G Pmpcb peptidase, mitochondrial processing subunit beta multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PMPCB mRNA CTD PMID:19167446 NCBI chr 4:13,297,583...13,310,363
Ensembl chr 4:13,297,559...13,310,367 		JBrowse link
G Pnp purine nucleoside phosphorylase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PNP mRNA CTD PMID:19167446 NCBI chr15:24,170,607...24,178,269
Ensembl chr15:24,170,602...24,203,986 		JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of POLA1 mRNA CTD PMID:19167446 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536 		JBrowse link
G Pola2 DNA polymerase alpha 2, accessory subunit multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of POLA2 mRNA CTD PMID:19167446 NCBI chr 1:203,227,183...203,251,350
Ensembl chr 1:203,203,388...203,251,348 		JBrowse link
G Pold1 DNA polymerase delta 1, catalytic subunit multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of POLD1 mRNA CTD PMID:19167446 NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465 		JBrowse link
G Pold2 DNA polymerase delta 2, accessory subunit multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of POLD2 mRNA CTD PMID:19167446 NCBI chr14:80,748,971...80,755,188
Ensembl chr14:80,748,974...80,755,160 		JBrowse link
G Pold3 DNA polymerase delta 3, accessory subunit multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of POLD3 mRNA CTD PMID:19167446 NCBI chr 1:154,417,893...154,456,687
Ensembl chr 1:154,418,084...154,456,665 		JBrowse link
G Pole DNA polymerase epsilon, catalytic subunit multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of POLE mRNA CTD PMID:19167446 NCBI chr12:46,345,420...46,393,984
Ensembl chr12:46,345,420...46,393,939 		JBrowse link
G Pole2 DNA polymerase epsilon 2, accessory subunit multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of POLE2 mRNA CTD PMID:19167446 NCBI chr 6:87,674,702...87,712,723
Ensembl chr 6:87,674,702...87,699,305 		JBrowse link
G Pole3 DNA polymerase epsilon 3, accessory subunit multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of POLE3 mRNA CTD PMID:19167446 NCBI chr 5:75,973,941...75,977,175
Ensembl chr 5:75,974,717...75,977,231
Ensembl chr 7:75,974,717...75,977,231 		JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PPAT mRNA CTD PMID:19167446 NCBI chr14:31,215,741...31,250,144
Ensembl chr14:31,216,165...31,250,144 		JBrowse link
G Ppif peptidylprolyl isomerase F multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PPIF mRNA CTD PMID:19167446 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913 		JBrowse link
G Ppl periplakin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PPL mRNA CTD PMID:19167446 NCBI chr10:10,450,919...10,496,575
Ensembl chr10:10,450,919...10,496,575 		JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PPP1R10 mRNA CTD PMID:19167446 NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611 		JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PPP2R2A mRNA CTD PMID:19167446 NCBI chr15:41,204,659...41,263,924
Ensembl chr15:41,204,200...41,263,924 		JBrowse link
G Ppp2r3a protein phosphatase 2, regulatory subunit B'', alpha multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PPP2R3A mRNA CTD PMID:19167446 NCBI chr 8:101,703,512...101,841,530
Ensembl chr 8:101,704,778...101,841,502 		JBrowse link
G Ppp3cc protein phosphatase 3 catalytic subunit gamma multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PPP3CC mRNA CTD PMID:19167446 NCBI chr15:45,289,917...45,362,012
Ensembl chr15:45,290,373...45,361,832 		JBrowse link
G Prdx4 peroxiredoxin 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PRDX4 mRNA CTD PMID:19167446 NCBI chr  X:40,026,762...40,044,066
Ensembl chr  X:40,026,651...40,044,066 		JBrowse link
G Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PREX1 mRNA CTD PMID:19167446 NCBI chr 3:155,306,950...155,456,688
Ensembl chr 3:155,306,950...155,456,688 		JBrowse link
G Prim1 DNA primase subunit 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PRIM1 mRNA CTD PMID:19167446 NCBI chr 7:446,342...462,526
Ensembl chr 7:431,805...462,526 		JBrowse link
G Prim2 DNA primase subunit 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PRIM2 mRNA CTD PMID:19167446 NCBI chr 9:35,692,376...35,904,521
Ensembl chr 9:35,692,376...35,903,030 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PRKDC mRNA CTD PMID:19167446 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Prpf4 pre-mRNA splicing tri-snRNP complex factor 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PRPF4 mRNA CTD PMID:19167446 NCBI chr 5:75,859,934...75,873,924
Ensembl chr 5:75,859,924...75,873,919 		JBrowse link
G Prr14 proline rich 14 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PRR14 mRNA CTD PMID:19167446 NCBI chr 1:182,083,838...182,089,330
Ensembl chr 1:182,084,126...182,089,317 		JBrowse link
G Prrc2a proline-rich coiled-coil 2A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PRRC2A mRNA CTD PMID:19167446 NCBI chr20:3,658,391...3,674,143
Ensembl chr20:3,658,695...3,674,130 		JBrowse link
G Prrc2c proline-rich coiled-coil 2C multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PRRC2C mRNA CTD PMID:19167446 NCBI chr13:75,003,995...75,073,701
Ensembl chr13:75,004,010...75,073,643 		JBrowse link
G Prrt3 proline-rich transmembrane protein 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PRRT3 mRNA CTD PMID:19167446 NCBI chr 4:146,641,173...146,650,487
Ensembl chr 4:146,641,173...146,650,317 		JBrowse link
G Prss23 serine protease 23 multiple interactions
decreases expression		 ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PRSS23 mRNA
2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of PRSS23 mRNA		 CTD PMID:19167446 NCBI chr 1:143,402,725...143,422,182
Ensembl chr 1:143,401,396...143,422,091 		JBrowse link
G Psip1 PC4 and SRSF1 interacting protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PSIP1 mRNA CTD PMID:19167446 NCBI chr 5:97,847,010...97,879,280
Ensembl chr 5:97,847,015...97,879,257 		JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PSMC3 mRNA CTD PMID:19167446 NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358 		JBrowse link
G Psrc1 proline and serine rich coiled-coil 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PSRC1 mRNA CTD PMID:19167446 NCBI chr 2:196,022,361...196,026,874
Ensembl chr 2:196,022,361...196,026,874 		JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PTBP1 mRNA CTD PMID:19167446 NCBI chr 7:9,842,574...9,852,332
Ensembl chr 7:9,842,574...9,852,397 		JBrowse link
G Ptges prostaglandin E synthase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PTGES mRNA CTD PMID:19167446 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PTP4A1 mRNA CTD PMID:19167446 NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964 		JBrowse link
G Ptpn12 protein tyrosine phosphatase, non-receptor type 12 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PTPN12 mRNA CTD PMID:19167446 NCBI chr 4:14,020,997...14,092,931
Ensembl chr 4:14,021,052...14,092,927 		JBrowse link
G Ptpn21 protein tyrosine phosphatase, non-receptor type 21 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PTPN21 mRNA CTD PMID:19167446 NCBI chr 6:117,933,066...117,998,095
Ensembl chr 6:117,933,066...117,998,095 		JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PTTG1 mRNA CTD PMID:19167446 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837 		JBrowse link
G Pus3 pseudouridine synthase 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PUS3 mRNA CTD PMID:19167446 NCBI chr 8:33,910,461...33,918,716
Ensembl chr 8:33,911,357...33,918,714 		JBrowse link
G Pyroxd1 pyridine nucleotide-disulphide oxidoreductase domain 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of PYROXD1 mRNA CTD PMID:19167446 NCBI chr 4:175,292,124...175,311,143
Ensembl chr 4:175,292,177...175,308,689 		JBrowse link
G Qser1 glutamine and serine rich 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of QSER1 mRNA CTD PMID:19167446 NCBI chr 3:91,137,516...91,202,426
Ensembl chr 3:91,140,967...91,202,052 		JBrowse link
G Rab2a RAB2A, member RAS oncogene family multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RAB2 mRNA CTD PMID:19167446 NCBI chr 5:21,676,017...21,740,035
Ensembl chr 5:21,676,129...21,739,899 		JBrowse link
G Rab31 RAB31, member RAS oncogene family multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RAB31 mRNA CTD PMID:19167446 NCBI chr 9:105,246,712...105,382,973
Ensembl chr 9:105,246,709...105,381,253 		JBrowse link
G Rab32 RAB32, member RAS oncogene family multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RAB32 mRNA CTD PMID:19167446 NCBI chr 1:4,946,193...4,961,003
Ensembl chr 1:4,945,036...4,960,934 		JBrowse link
G Rab40b Rab40b, member RAS oncogene family multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RAB40B mRNA CTD PMID:19167446 NCBI chr10:106,631,514...106,659,090
Ensembl chr10:106,631,514...106,659,090 		JBrowse link
G Rab8a RAB8A, member RAS oncogene family multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RAB8A mRNA CTD PMID:19167446 NCBI chr16:17,654,027...17,675,385
Ensembl chr16:17,654,034...17,675,678 		JBrowse link
G Racgap1 Rac GTPase-activating protein 1 increases expression
multiple interactions		 ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased expression of RACGAP1 mRNA
[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RACGAP1 mRNA		 CTD PMID:19167446 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831 		JBrowse link
G Rad21 RAD21 cohesin complex component multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RAD21 mRNA CTD PMID:19167446 NCBI chr 7:83,287,867...83,314,810
Ensembl chr 7:83,287,870...83,314,817 		JBrowse link
G Rad51 RAD51 recombinase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RAD51 mRNA CTD PMID:19167446 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
G Rad51ap1 RAD51 associated protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RAD51AP1 mRNA CTD PMID:19167446 NCBI chr 4:159,759,454...159,772,473
Ensembl chr 4:159,759,459...159,772,524 		JBrowse link
G Rad51c RAD51 paralog C multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RAD51C mRNA CTD PMID:19167446 NCBI chr10:72,205,032...72,231,643
Ensembl chr10:72,205,032...72,231,248 		JBrowse link
G Rad54b RAD54 homolog B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RAD54B mRNA CTD PMID:19167446 NCBI chr 5:25,032,112...25,104,630
Ensembl chr 5:25,032,066...25,104,616 		JBrowse link
G Rad54l RAD54 like multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RAD54L mRNA CTD PMID:19167446 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070 		JBrowse link
G Ranbp1 RAN binding protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RANBP1 mRNA CTD PMID:19167446 NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838 		JBrowse link
G Rangap1 RAN GTPase activating protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RANGAP1 mRNA CTD PMID:19167446 NCBI chr 7:113,224,695...113,250,441
Ensembl chr 7:113,224,703...113,250,438 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RAPGEF2 mRNA CTD PMID:19167446 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247 		JBrowse link
G Rapgefl1 Rap guanine nucleotide exchange factor like 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RAPGEFL1 mRNA CTD PMID:19167446 NCBI chr10:83,793,711...83,810,373
Ensembl chr10:83,793,694...83,810,371 		JBrowse link
G Rasd1 ras related dexamethasone induced 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RASD1 mRNA CTD PMID:19167446 NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186 		JBrowse link
G Rasef RAS and EF hand domain containing multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RASEF mRNA CTD PMID:19167446 NCBI chr 5:87,548,908...87,619,286
Ensembl chr 5:87,548,908...87,619,031 		JBrowse link
G Rasl11b RAS-like family 11 member B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RASL11B mRNA CTD PMID:19167446 NCBI chr14:34,014,924...34,019,146
Ensembl chr14:34,014,509...34,019,152 		JBrowse link
G Rassf3 Ras association domain family member 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RASSF3 mRNA CTD PMID:19167446 NCBI chr 7:56,935,888...57,000,554
Ensembl chr 7:56,935,973...57,000,553 		JBrowse link
G Raver1 ribonucleoprotein, PTB-binding 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RAVER1 mRNA CTD PMID:19167446 NCBI chr 8:19,610,464...19,629,188
Ensembl chr 8:19,610,466...19,629,152 		JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RB1CC1 mRNA CTD PMID:19167446 NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560 		JBrowse link
G Rbbp4 RB binding protein 4, chromatin remodeling factor multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RBBP4 mRNA CTD PMID:19167446 NCBI chr 5:141,655,863...141,675,157
Ensembl chr 5:141,638,421...141,675,284 		JBrowse link
G Rbbp8 RB binding protein 8, endonuclease multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RBBP8 mRNA CTD PMID:19167446 NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846 		JBrowse link
G Rbbp9 RB binding protein 9, serine hydrolase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RBBP9 mRNA CTD PMID:19167446 NCBI chr 3:131,925,095...131,939,042
Ensembl chr 3:131,925,341...131,932,156 		JBrowse link
G Rbfox2 RNA binding fox-1 homolog 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RBFOX2 mRNA CTD PMID:19167446 NCBI chr 7:108,810,627...109,054,420
Ensembl chr 7:108,810,628...109,054,691 		JBrowse link
G Rbm10 RNA binding motif protein 10 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RBM10 mRNA CTD PMID:19167446 NCBI chr  X:1,540,399...1,572,571
Ensembl chr  X:1,540,398...1,572,575 		JBrowse link
G Rbm15 RNA binding motif protein 15 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RBM15 mRNA CTD PMID:19167446 NCBI chr 2:194,945,974...194,954,498
Ensembl chr 2:194,945,974...194,954,703 		JBrowse link
G Rbms1 RNA binding motif, single stranded interacting protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RBMS1 mRNA CTD PMID:19167446 NCBI chr 3:45,195,828...45,420,406
Ensembl chr 3:45,197,972...45,420,376 		JBrowse link
G Rcan1 regulator of calcineurin 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RCAN1 mRNA CTD PMID:19167446 NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045 		JBrowse link
G Rccd1 RCC1 domain containing 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RCCD1 mRNA CTD PMID:19167446 NCBI chr 1:134,271,870...134,281,556
Ensembl chr 1:134,271,857...134,280,781 		JBrowse link
G Rcor3 REST corepressor 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RCOR3 mRNA CTD PMID:19167446 NCBI chr13:103,624,966...103,665,565
Ensembl chr13:103,624,971...103,665,565 		JBrowse link
G Rdm1 RAD52 motif containing 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RDM1 mRNA CTD PMID:19167446 NCBI chr10:86,562,871...86,573,034
Ensembl chr10:86,539,553...86,573,034 		JBrowse link
G Recql4 RecQ like helicase 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RECQL4 mRNA CTD PMID:19167446 NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619 		JBrowse link
G Reep3 receptor accessory protein 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of REEP3 mRNA CTD PMID:19167446 NCBI chr20:21,493,868...21,578,698
Ensembl chr20:21,493,954...21,578,697 		JBrowse link
G Reep5 receptor accessory protein 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of REEP5 mRNA CTD PMID:19167446 NCBI chr18:25,945,375...25,983,271
Ensembl chr18:25,945,381...25,976,509 		JBrowse link
G Rerg RAS-like, estrogen-regulated, growth-inhibitor multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RERG mRNA CTD PMID:19167446 NCBI chr 4:169,981,634...170,089,777
Ensembl chr 4:169,982,279...170,089,715 		JBrowse link
G Ret ret proto-oncogene multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RET mRNA CTD PMID:19167446 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
G Rfc2 replication factor C subunit 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RFC2 mRNA CTD PMID:19167446 NCBI chr12:22,120,449...22,133,576
Ensembl chr12:22,120,010...22,133,557 		JBrowse link
G Rfc3 replication factor C subunit 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RFC3 mRNA CTD PMID:19167446 NCBI chr12:1,000,987...1,011,778
Ensembl chr12:1,000,994...1,011,778 		JBrowse link
G Rfc4 replication factor C subunit 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RFC4 mRNA CTD PMID:19167446 NCBI chr11:77,749,642...77,764,123
Ensembl chr11:77,749,638...77,764,122 		JBrowse link
G Rfc5 replication factor C subunit 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RFC5 mRNA CTD PMID:19167446 NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312 		JBrowse link
G Rftn1 raftlin lipid raft linker 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RFTN1 mRNA CTD PMID:19167446 NCBI chr 9:10,804,611...11,002,084
Ensembl chr 9:10,804,611...11,002,084 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RGS2 mRNA CTD PMID:19167446 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rhbdf1 rhomboid 5 homolog 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RHBDF1 mRNA CTD PMID:19167446 NCBI chr10:15,406,832...15,419,765
Ensembl chr10:15,406,859...15,419,763 		JBrowse link
G Rhno1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RHNO1 mRNA CTD PMID:19167446 NCBI chr 4:161,634,047...161,639,437
Ensembl chr 4:161,634,048...161,639,371 		JBrowse link
G Rhoq ras homolog family member Q multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RHOQ mRNA CTD PMID:19167446 NCBI chr 6:7,613,632...7,652,047 JBrowse link
G Rhot1 ras homolog family member T1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RHOT1 mRNA CTD PMID:19167446 NCBI chr10:65,198,700...65,262,807
Ensembl chr10:65,170,560...65,262,804 		JBrowse link
G Rmdn2 regulator of microtubule dynamics 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RMDN2 mRNA CTD PMID:19167446 NCBI chr 6:15,372,569...15,443,000
Ensembl chr 6:15,375,496...15,441,480 		JBrowse link
G Rmi1 RecQ mediated genome instability 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RMI1 mRNA CTD PMID:19167446 NCBI chr17:6,256,533...6,264,523
Ensembl chr17:6,256,450...6,264,695 		JBrowse link
G Rmi2 RecQ mediated genome instability 2 increases expression
multiple interactions		 ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased expression of RMI2 mRNA
[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RMI2 mRNA		 CTD PMID:19167446 NCBI chr10:4,829,333...4,837,264
Ensembl chr10:4,830,553...4,837,235 		JBrowse link
G Rnaseh2a ribonuclease H2, subunit A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RNASEH2A mRNA CTD PMID:19167446 NCBI chr19:23,186,325...23,196,045
Ensembl chr19:23,186,383...23,196,041 		JBrowse link
G Rnf187 ring finger protein 187 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RNF187 mRNA CTD PMID:19167446 NCBI chr10:43,709,493...43,715,392
Ensembl chr10:43,702,357...43,716,157 		JBrowse link
G Rnf19a ring finger protein 19A, RBR E3 ubiquitin protein ligase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RNF19A mRNA CTD PMID:19167446 NCBI chr 7:67,425,833...67,465,214
Ensembl chr 7:67,425,837...67,465,222 		JBrowse link
G Rnf26 ring finger protein 26 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RNF26 mRNA CTD PMID:19167446 NCBI chr 8:44,454,551...44,456,745
Ensembl chr 8:44,454,292...44,457,331 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ROCK2 mRNA CTD PMID:19167446 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
G Rpa1 replication protein A1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RPA1 mRNA CTD PMID:19167446 NCBI chr10:60,148,869...60,199,970
Ensembl chr10:60,148,793...60,199,949 		JBrowse link
G Rpa3 replication protein A3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RPA3 mRNA CTD PMID:19167446 NCBI chr 4:36,304,649...36,307,755
Ensembl chr 4:36,304,651...36,307,709 		JBrowse link
G Rpl39l1 ribosomal protein L39 like 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RPL39L mRNA CTD PMID:19167446 NCBI chr10:5,455,712...5,459,828
Ensembl chr10:5,454,559...5,462,029 		JBrowse link
G Rragc Ras-related GTP binding C multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RRAGC mRNA CTD PMID:19167446 NCBI chr 5:136,148,239...136,167,773
Ensembl chr 5:136,148,276...136,167,767 		JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RRM1 mRNA CTD PMID:19167446 NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RRM2 mRNA CTD PMID:19167446 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773 		JBrowse link
G Rsrc1 arginine and serine rich coiled-coil 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RSRC1 mRNA CTD PMID:19167446 NCBI chr 2:151,226,821...151,632,771
Ensembl chr 2:151,231,156...151,632,765 		JBrowse link
G Rsu1 Ras suppressor protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RSU1 mRNA CTD PMID:19167446 NCBI chr17:76,128,774...76,377,515
Ensembl chr17:76,188,812...76,377,454 		JBrowse link
G Rundc3b RUN domain containing 3B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RUNDC3B mRNA CTD PMID:19167446 NCBI chr 4:25,462,543...25,599,477
Ensembl chr 4:25,462,752...25,599,471 		JBrowse link
G S100a10 S100 calcium binding protein A10 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of S100A10 mRNA CTD PMID:19167446 NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661 		JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of S1PR3 mRNA CTD PMID:19167446 NCBI chr17:13,781,050...13,794,408
Ensembl chr17:13,781,050...13,794,505 		JBrowse link
G Sae1 SUMO1 activating enzyme subunit 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SAE1 mRNA CTD PMID:19167446 NCBI chr 1:77,030,961...77,086,937
Ensembl chr 1:77,030,965...77,086,986 		JBrowse link
G Sall4 spalt-like transcription factor 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SALL4 mRNA CTD PMID:19167446 NCBI chr 3:157,474,067...157,491,055
Ensembl chr 3:157,474,642...157,490,822 		JBrowse link
G Sash1 SAM and SH3 domain containing 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SASH1 mRNA CTD PMID:19167446 NCBI chr 1:3,119,915...3,418,536
Ensembl chr 1:3,121,332...3,439,870 		JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SAT1 mRNA CTD PMID:19167446 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SCARB1 mRNA CTD PMID:19167446 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Scarb2 scavenger receptor class B, member 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SCARB2 mRNA CTD PMID:19167446 NCBI chr14:15,558,271...15,609,813
Ensembl chr14:15,558,236...15,609,813 		JBrowse link
G Sccpdh saccharopine dehydrogenase (putative) multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SCCPDH mRNA CTD PMID:19167446 NCBI chr13:91,400,120...91,421,875
Ensembl chr13:91,400,190...91,422,222 		JBrowse link
G Sele selectin E decreases secretion ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased secretion of SELE protein CTD PMID:29740324 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741 		JBrowse link
G Selenop selenoprotein P multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SELENOP mRNA CTD PMID:19167446 NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852 		JBrowse link
G Sephs1 selenophosphate synthetase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SEPHS1 mRNA CTD PMID:19167446 NCBI chr17:73,354,435...73,382,803
Ensembl chr17:73,356,530...73,382,593 		JBrowse link
G Serinc5 serine incorporator 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SERINC5 mRNA CTD PMID:19167446 NCBI chr 2:23,846,899...23,950,346
Ensembl chr 2:23,846,900...23,950,346 		JBrowse link
G Sf1 splicing factor 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SF1 mRNA CTD PMID:19167446 NCBI chr 1:203,670,016...203,683,432
Ensembl chr 1:203,670,018...203,684,330 		JBrowse link
G Sf3b3 splicing factor 3b, subunit 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SF3B3 mRNA CTD PMID:19167446 NCBI chr19:38,782,749...38,820,271
Ensembl chr19:38,783,040...38,820,245 		JBrowse link
G Sfn stratifin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SFN mRNA CTD PMID:19167446 NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314 		JBrowse link
G Sfxn2 sideroflexin 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SFXN2 mRNA CTD PMID:19167446 NCBI chr 1:245,447,014...245,459,312
Ensembl chr 1:245,447,015...245,468,411
Ensembl chr 1:245,447,015...245,468,411 		JBrowse link
G Sgcg sarcoglycan, gamma multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SGCG mRNA CTD PMID:19167446 NCBI chr15:35,388,836...35,435,072
Ensembl chr15:35,386,534...35,435,148 		JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SGK3 mRNA CTD PMID:19167446 NCBI chr 5:9,345,761...9,472,243
Ensembl chr 5:9,346,040...9,415,476 		JBrowse link
G Sgo1 shugoshin 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SGO1 mRNA CTD PMID:19167446 NCBI chr 9:6,672,109...6,687,908
Ensembl chr 9:6,672,123...6,687,805 		JBrowse link
G Sgo2 shugoshin 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SGO2 mRNA CTD PMID:19167446 NCBI chr 9:59,548,605...59,573,229
Ensembl chr 9:59,548,683...59,573,229 		JBrowse link
G Sh3bgrl1 SH3 domain binding glutamate rich protein like 1 multiple interactions
decreases expression		 ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SH3BGRL mRNA
2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of SH3BGRL mRNA		 CTD PMID:19167446 NCBI chr  X:74,167,029...74,263,783
Ensembl chr  X:74,166,871...74,263,783 		JBrowse link
G Sh3bp4 SH3-domain binding protein 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SH3BP4 mRNA CTD PMID:19167446 NCBI chr 9:89,660,156...89,739,163
Ensembl chr 9:89,660,156...89,739,163 		JBrowse link
G Sh3kbp1 SH3 domain-containing kinase-binding protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SH3KBP1 mRNA CTD PMID:19167446 NCBI chr  X:34,877,862...35,223,013
Ensembl chr  X:34,877,866...35,222,747 		JBrowse link
G Shcbp1 SHC binding and spindle associated 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SHCBP1 mRNA CTD PMID:19167446 NCBI chr16:84,672,277...84,703,843
Ensembl chr16:84,672,321...84,703,844 		JBrowse link
G Shisa2 shisa family member 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SHISA2 mRNA CTD PMID:19167446 NCBI chr15:33,806,715...33,811,013
Ensembl chr15:33,805,958...33,811,013 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SHMT1 mRNA CTD PMID:19167446 NCBI chr10:45,468,698...45,490,833
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SHMT2 mRNA CTD PMID:19167446 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236 		JBrowse link
G Ska1 spindle and kinetochore associated complex subunit 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SKA1 mRNA CTD PMID:19167446 NCBI chr18:67,794,722...67,805,037
Ensembl chr18:67,794,725...67,805,037 		JBrowse link
G Ska2 spindle and kinetochore associated complex subunit 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SKA2 mRNA CTD PMID:19167446 NCBI chr10:71,921,474...71,939,461
Ensembl chr10:71,921,582...71,939,458 		JBrowse link
G Ska3 spindle and kinetochore associated complex subunit 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SKA3 mRNA CTD PMID:19167446 NCBI chr15:31,951,812...31,971,010
Ensembl chr15:31,951,825...31,971,010 		JBrowse link
G Skp2 S-phase kinase associated protein 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SKP2 mRNA CTD PMID:19167446 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338 		JBrowse link
G Slbp stem-loop histone mRNA binding protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLBP mRNA CTD PMID:19167446 NCBI chr14:77,071,441...77,081,911
Ensembl chr14:77,071,632...77,081,906 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SLC12A2 mRNA CTD PMID:19167446 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440 		JBrowse link
G Slc12a4 solute carrier family 12 member 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLC12A4 mRNA CTD PMID:19167446 NCBI chr19:33,838,418...33,860,369
Ensembl chr19:33,838,419...33,860,331 		JBrowse link
G Slc12a8 solute carrier family 12, member 8 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SLC12A8 mRNA CTD PMID:19167446 NCBI chr11:67,116,876...67,266,548
Ensembl chr11:67,116,877...67,266,834 		JBrowse link
G Slc1a4 solute carrier family 1 member 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLC1A4 mRNA CTD PMID:19167446 NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418 		JBrowse link
G Slc25a11 solute carrier family 25 member 11 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLC25A11 mRNA CTD PMID:19167446 NCBI chr10:55,357,590...55,360,441
Ensembl chr10:55,357,597...55,360,410 		JBrowse link
G Slc25a39 solute carrier family 25, member 39 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLC25A39 mRNA CTD PMID:19167446 NCBI chr10:87,362,494...87,367,358
Ensembl chr10:87,362,490...87,367,260 		JBrowse link
G Slc26a11 solute carrier family 26 member 11 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SLC26A11 mRNA CTD PMID:19167446 NCBI chr10:104,613,498...104,635,873
Ensembl chr10:104,613,564...104,635,970 		JBrowse link
G Slc27a2 solute carrier family 27 member 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLC27A2 mRNA CTD PMID:19167446 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208 		JBrowse link
G Slc27a3 solute carrier family 27 member 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLC27A3 mRNA CTD PMID:19167446 NCBI chr 2:175,853,241...175,857,909
Ensembl chr 2:175,853,241...175,857,909 		JBrowse link
G Slc29a1 solute carrier family 29 member 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLC29A1 mRNA CTD PMID:19167446 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203 		JBrowse link
G Slc2a4rg SLC2A4 regulator multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLC2A4RG mRNA CTD PMID:19167446 NCBI chr 3:168,493,975...168,497,616 JBrowse link
G Slc35d2 solute carrier family 35 member D2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SLC35D2 mRNA CTD PMID:19167446 NCBI chr17:987,899...1,019,747
Ensembl chr17:988,157...1,019,743 		JBrowse link
G Slc37a4 solute carrier family 37 member 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLC37A4 mRNA CTD PMID:19167446 NCBI chr 8:44,723,216...44,729,301
Ensembl chr 8:44,723,339...44,729,301 		JBrowse link
G Slc39a8 solute carrier family 39 member 8 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLC39A8 mRNA CTD PMID:19167446 NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129 		JBrowse link
G Slc6a14 solute carrier family 6 member 14 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLC6A14 mRNA CTD PMID:19167446 NCBI chr  X:112,314,643...112,375,412
Ensembl chr  X:112,314,691...112,375,096 		JBrowse link
G Slc7a1 solute carrier family 7 member 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLC7A1 mRNA CTD PMID:19167446 NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 decreases expression
multiple interactions		 ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of SLC7A11 mRNA
[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SLC7A11 mRNA		 CTD PMID:19167446 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLC7A5 mRNA CTD PMID:19167446 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G Slf1 SMC5-SMC6 complex localization factor 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLF1 mRNA CTD PMID:19167446 NCBI chr 2:6,767,015...6,874,428
Ensembl chr 2:6,767,015...6,867,149 		JBrowse link
G Smad2 SMAD family member 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SMAD2 mRNA CTD PMID:19167446 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad3 SMAD family member 3 decreases expression
multiple interactions		 ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of SMAD3 mRNA
[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SMAD3 mRNA		 CTD PMID:19167446 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smc1a structural maintenance of chromosomes 1A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SMC1A mRNA CTD PMID:19167446 NCBI chr  X:21,103,323...21,148,053
Ensembl chr  X:21,103,282...21,148,056 		JBrowse link
G Smc2 structural maintenance of chromosomes 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SMC2 mRNA CTD PMID:19167446 NCBI chr 5:66,806,882...66,853,478
Ensembl chr 5:66,807,011...66,853,242 		JBrowse link
G Smc4 structural maintenance of chromosomes 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SMC4 mRNA CTD PMID:19167446 NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571 		JBrowse link
G Smyd2 SET and MYND domain containing 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SMYD2 mRNA CTD PMID:19167446 NCBI chr13:101,425,270...101,466,576
Ensembl chr13:101,425,273...101,466,576 		JBrowse link
G Snn stannin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SNN mRNA CTD PMID:19167446 NCBI chr10:4,572,933...4,581,606
Ensembl chr10:4,572,376...4,584,021 		JBrowse link
G Snora24 small nucleolar RNA, H/ACA box 24 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SNORA24 mRNA CTD PMID:19167446 NCBI chr 2:82,490,770...82,490,892
Ensembl chr 2:82,490,770...82,490,892
Ensembl chr 2:82,490,770...82,490,892 		JBrowse link
G Snord52 small nucleolar RNA, C/D box 52 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SNORD52 mRNA CTD PMID:19167446 NCBI chr20:3,878,412...3,878,477
Ensembl chr20:3,878,412...3,878,477 		JBrowse link
G Snrnp25 small nuclear ribonucleoprotein U11/U12 subunit 25 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SNRNP25 mRNA CTD PMID:19167446 NCBI chr10:15,420,482...15,423,806
Ensembl chr10:15,420,486...15,423,804 		JBrowse link
G Snrpa1 small nuclear ribonucleoprotein polypeptide A' multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SNRPA1 mRNA CTD PMID:19167446 NCBI chr 1:119,641,402...119,654,653
Ensembl chr 1:119,638,481...119,654,653 		JBrowse link
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SNRPB mRNA CTD PMID:19167446 NCBI chr 3:117,369,816...117,379,344
Ensembl chr 3:117,370,100...117,379,339 		JBrowse link
G Snx10 sorting nexin 10 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SNX10 mRNA CTD PMID:19167446 NCBI chr 4:80,612,648...80,677,005
Ensembl chr 4:80,612,669...80,676,996 		JBrowse link
G Snx24 sorting nexin 24 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SNX24 mRNA CTD PMID:19167446 NCBI chr18:46,670,987...46,826,070
Ensembl chr18:46,671,443...46,826,068 		JBrowse link
G Snx29 sorting nexin 29 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SNX29 mRNA CTD PMID:19167446 NCBI chr10:3,884,880...4,298,699
Ensembl chr10:3,888,301...4,298,655 		JBrowse link
G Snx6 sorting nexin 6 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SNX6 mRNA CTD PMID:19167446 NCBI chr 6:72,230,950...72,274,157
Ensembl chr 6:72,229,870...72,315,911 		JBrowse link
G Snx9 sorting nexin 9 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SNX9 mRNA CTD PMID:19167446 NCBI chr 1:46,424,897...46,510,096
Ensembl chr 1:46,423,553...46,509,036 		JBrowse link
G Socs2 suppressor of cytokine signaling 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SOCS2 mRNA CTD PMID:19167446 NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548 		JBrowse link
G Sox3 SRY-box transcription factor 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SOX3 mRNA CTD PMID:19167446 NCBI chr  X:139,308,608...139,310,687
Ensembl chr  X:139,309,329...139,310,678 		JBrowse link
G Sox4 SRY-box transcription factor 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SOX4 mRNA CTD PMID:19167446 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665 		JBrowse link
G Sox9 SRY-box transcription factor 9 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SOX9 mRNA CTD PMID:19167446 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Spag5 sperm associated antigen 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SPAG5 mRNA CTD PMID:19167446 NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745 		JBrowse link
G Spata7 spermatogenesis associated 7 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SPATA7 mRNA CTD PMID:19167446 NCBI chr 6:117,879,828...117,925,284
Ensembl chr 6:117,879,823...117,925,284 		JBrowse link
G Spc24 SPC24 component of NDC80 kinetochore complex multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SPC24 mRNA CTD PMID:19167446 NCBI chr 8:20,300,315...20,305,354
Ensembl chr 8:20,300,319...20,305,310 		JBrowse link
G Spc25 SPC25 component of NDC80 kinetochore complex multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SPC25 mRNA CTD PMID:19167446 NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959 		JBrowse link
G Spdl1 spindle apparatus coiled-coil protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SPDL1 mRNA CTD PMID:19167446 NCBI chr10:19,269,125...19,294,213
Ensembl chr10:19,269,127...19,294,127 		JBrowse link
G Spin4 spindlin family, member 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SPIN4 mRNA CTD PMID:19167446 NCBI chr  X:59,888,728...59,892,817
Ensembl chr  X:59,891,581...59,892,330 		JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SPRED2 mRNA CTD PMID:19167446 NCBI chr14:94,149,210...94,250,787
Ensembl chr14:94,148,837...94,249,162 		JBrowse link
G Sqor sulfide quinone oxidoreductase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SQOR mRNA CTD PMID:19167446 NCBI chr 3:109,841,225...109,886,724
Ensembl chr 3:109,841,250...109,960,778 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SQSTM1 mRNA CTD PMID:19167446 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Srd5a3 steroid 5 alpha-reductase 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SRD5A3 mRNA CTD PMID:19167446 NCBI chr14:32,046,408...32,060,796
Ensembl chr14:32,046,408...32,060,747 		JBrowse link
G Sri sorcin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SRI mRNA CTD PMID:19167446 NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077 		JBrowse link
G Srm spermidine synthase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SRM mRNA CTD PMID:19167446 NCBI chr 5:159,025,875...159,029,076
Ensembl chr 5:159,025,873...159,029,405 		JBrowse link
G Srprb SRP receptor subunit beta multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SRPRB mRNA CTD PMID:19167446 NCBI chr 8:103,768,685...103,782,632 JBrowse link
G Srrt serrate, RNA effector molecule multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SRRT mRNA CTD PMID:19167446 NCBI chr12:19,392,578...19,406,098
Ensembl chr12:19,392,625...19,406,095 		JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SRSF1 mRNA CTD PMID:19167446 NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336 		JBrowse link
G Ssbp2 single-stranded DNA binding protein 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SSBP2 mRNA CTD PMID:19167446 NCBI chr 2:22,650,488...22,938,669
Ensembl chr 2:22,651,258...22,933,696 		JBrowse link
G Ssrp1 structure specific recognition protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SSRP1 mRNA CTD PMID:19167446 NCBI chr 3:70,124,371...70,134,481
Ensembl chr 3:70,118,655...70,134,482 		JBrowse link
G St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ST8SIA4 mRNA CTD PMID:19167446 NCBI chr 9:95,990,131...96,084,661
Ensembl chr 9:95,993,503...96,084,653 		JBrowse link
G Stil STIL, centriolar assembly protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of STIL mRNA CTD PMID:19167446 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730 		JBrowse link
G Stk38l serine/threonine kinase 38 like multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of STK38L mRNA CTD PMID:19167446 NCBI chr 4:179,616,288...179,693,177
Ensembl chr 4:179,634,275...179,690,983 		JBrowse link
G Stmn1 stathmin 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of STMN1 mRNA CTD PMID:19167446 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154 		JBrowse link
G Ston2 stonin 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of STON2 mRNA CTD PMID:19167446 NCBI chr 6:110,567,485...110,676,376
Ensembl chr 6:110,567,485...110,676,376 		JBrowse link
G Strn3 striatin 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of STRN3 mRNA CTD PMID:19167446 NCBI chr 6:69,047,776...69,134,102
Ensembl chr 6:69,047,776...69,134,102 		JBrowse link
G Stx3 syntaxin 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of STX3 mRNA CTD PMID:19167446 NCBI chr 1:208,617,018...208,686,240
Ensembl chr 1:208,639,115...208,685,805 		JBrowse link
G Stx7 syntaxin 7 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of STX7 mRNA CTD PMID:19167446 NCBI chr 1:21,197,075...21,237,320
Ensembl chr 1:21,197,075...21,237,279 		JBrowse link
G Sulf2 sulfatase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SULF2 mRNA CTD PMID:19167446 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415 		JBrowse link
G Supt16h SPT16 homolog, facilitates chromatin remodeling subunit multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SUPT16H mRNA CTD PMID:19167446 NCBI chr15:24,867,697...24,904,818
Ensembl chr15:24,866,489...24,904,846 		JBrowse link
G Suv39h2 SUV39H2 histone lysine methyltransferase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SUV39H2 mRNA CTD PMID:19167446 NCBI chr17:74,756,290...74,775,332
Ensembl chr17:74,756,306...74,775,332 		JBrowse link
G Swap70 switching B-cell complex subunit SWAP70 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SWAP70 mRNA CTD PMID:19167446 NCBI chr 1:164,267,588...164,328,796
Ensembl chr 1:164,267,609...164,328,794 		JBrowse link
G Syce2 synaptonemal complex central element protein 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SYCE2 mRNA CTD PMID:19167446 NCBI chr19:23,266,236...23,291,265
Ensembl chr19:23,268,869...23,300,980 		JBrowse link
G Syde2 synapse defective Rho GTPase homolog 2 multiple interactions
decreases expression		 ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SYDE2 mRNA
2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of SYDE2 mRNA		 CTD PMID:19167446 NCBI chr 2:234,897,975...234,930,994
Ensembl chr 2:234,897,717...234,930,994 		JBrowse link
G Syngr3 synaptogyrin 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SYNGR3 mRNA CTD PMID:19167446 NCBI chr10:13,710,553...13,715,309
Ensembl chr10:13,704,998...13,715,669 		JBrowse link
G Sytl2 synaptotagmin-like 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of SYTL2 mRNA CTD PMID:19167446 NCBI chr 1:144,272,870...144,379,310
Ensembl chr 1:144,273,360...144,379,222 		JBrowse link
G Sytl4 synaptotagmin-like 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SYTL4 mRNA CTD PMID:19167446 NCBI chr  X:97,135,496...97,185,867
Ensembl chr  X:97,135,500...97,185,854 		JBrowse link
G Sytl5 synaptotagmin-like 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SYTL5 mRNA CTD PMID:19167446 NCBI chr  X:12,775,529...13,030,134
Ensembl chr  X:12,788,698...13,030,175 		JBrowse link
G Tacc3 transforming, acidic coiled-coil containing protein 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TACC3 mRNA CTD PMID:19167446 NCBI chr14:77,051,209...77,065,343
Ensembl chr14:77,051,215...77,065,219 		JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TACSTD2 mRNA CTD PMID:19167446 NCBI chr 4:96,707,950...96,709,650
Ensembl chr 4:96,707,951...96,709,650 		JBrowse link
G Taf5 TATA-box binding protein associated factor 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TAF5 mRNA CTD PMID:19167446 NCBI chr 1:245,958,428...245,973,914
Ensembl chr 1:245,958,428...245,973,914 		JBrowse link
G Tanc2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TANC2 mRNA CTD PMID:19167446 NCBI chr10:90,553,124...90,873,477
Ensembl chr10:90,553,002...90,868,756 		JBrowse link
G Taok3 TAO kinase 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TAOK3 mRNA CTD PMID:19167446 NCBI chr12:39,312,354...39,473,656
Ensembl chr12:39,314,027...39,461,244 		JBrowse link
G Tars2 threonyl-tRNA synthetase 2, mitochondrial multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TARS2 mRNA CTD PMID:19167446 NCBI chr 2:183,293,095...183,310,210
Ensembl chr 2:183,293,097...183,310,184 		JBrowse link
G Tbcd tubulin folding cofactor D multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TBCD mRNA CTD PMID:19167446 NCBI chr10:106,717,340...106,874,126
Ensembl chr10:106,717,367...106,874,122 		JBrowse link
G Tbl1x transducin (beta)-like 1 X-linked decreases expression ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of TBL1X mRNA CTD PMID:19167446 NCBI chr  X:41,574,558...41,731,117
Ensembl chr  X:41,576,047...41,731,101 		JBrowse link
G Tcf19 transcription factor 19 multiple interactions
increases expression		 ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TCF19 mRNA
2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased expression of TCF19 mRNA		 CTD PMID:19167446 NCBI chr20:3,218,756...3,222,861
Ensembl chr20:3,218,693...3,223,271 		JBrowse link
G Tcf7l1 transcription factor 7 like 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TCF7L1 mRNA CTD PMID:19167446 NCBI chr 4:104,680,734...104,846,086
Ensembl chr 4:104,680,739...104,845,287 		JBrowse link
G Tdp1 tyrosyl-DNA phosphodiesterase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TDP1 mRNA CTD PMID:19167446 NCBI chr 6:119,163,192...119,231,029
Ensembl chr 6:119,163,166...119,231,021 		JBrowse link
G Tecr trans-2,3-enoyl-CoA reductase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TECR mRNA CTD PMID:19167446 NCBI chr19:24,526,700...24,568,168
Ensembl chr19:24,541,615...24,568,168 		JBrowse link
G Tex30 testis expressed 30 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TEX30 mRNA CTD PMID:19167446 NCBI chr 9:46,243,416...46,252,273
Ensembl chr 9:46,242,748...46,252,249 		JBrowse link
G Tfap2c transcription factor AP-2 gamma multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TFAP2C mRNA CTD PMID:19167446 NCBI chr 3:161,315,114...161,322,998
Ensembl chr 3:161,315,031...161,322,995 		JBrowse link
G Tfdp1 transcription factor Dp-1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TFDP1 mRNA CTD PMID:19167446 NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817 		JBrowse link
G Tff1 trefoil factor 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TFF1 mRNA CTD PMID:19167446 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597 		JBrowse link
G Tff3 trefoil factor 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TFF3 mRNA CTD PMID:19167446 NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054 		JBrowse link
G Tfpi tissue factor pathway inhibitor multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TFPI mRNA CTD PMID:19167446 NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TGFB2 mRNA CTD PMID:19167446 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TGFBR1 mRNA CTD PMID:19167446 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TGIF1 mRNA CTD PMID:19167446 NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802 		JBrowse link
G Tgif2 TGFB-induced factor homeobox 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TGIF2 mRNA CTD PMID:19167446 NCBI chr 3:145,333,152...145,348,599
Ensembl chr 3:145,333,418...145,348,596 		JBrowse link
G Thbs1 thrombospondin 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of THBS1 mRNA CTD PMID:19167446 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Them6 thioesterase superfamily member 6 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of THEM6 mRNA CTD PMID:19167446 NCBI chr 7:106,606,570...106,609,747
Ensembl chr 7:106,606,570...106,609,746 		JBrowse link
G Thsd4 thrombospondin type 1 domain containing 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of THSD4 mRNA CTD PMID:19167446 NCBI chr 8:60,384,636...60,984,419
Ensembl chr 8:60,386,875...61,024,995 		JBrowse link
G Ticrr TOPBP1-interacting checkpoint and replication regulator multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TICRR mRNA CTD PMID:19167446 NCBI chr 1:133,597,618...133,639,513
Ensembl chr 1:133,597,716...133,639,523 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TIGAR mRNA CTD PMID:19167446 NCBI chr 4:159,927,136...159,946,077
Ensembl chr 4:159,927,139...159,946,029 		JBrowse link
G Timeless timeless circadian regulator multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TIMELESS mRNA CTD PMID:19167446 NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TIMP2 mRNA CTD PMID:19167446 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Tipin timeless interacting protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TIPIN mRNA CTD PMID:19167446 NCBI chr 8:64,780,813...64,801,358
Ensembl chr 8:64,780,828...64,801,352 		JBrowse link
G Tk1 thymidine kinase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TK1 mRNA CTD PMID:19167446 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920 		JBrowse link
G Tkfc triokinase and FMN cyclase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TKFC mRNA CTD PMID:19167446 NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737 		JBrowse link
G Tle1 TLE family member 1, transcriptional corepressor multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TLE1 mRNA CTD PMID:19167446 NCBI chr 5:85,851,827...85,934,806
Ensembl chr 5:85,851,827...85,934,774 		JBrowse link
G Tm4sf1 transmembrane 4 L six family member 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TM4SF1 mRNA CTD PMID:19167446 NCBI chr 2:141,456,950...141,466,146
Ensembl chr 2:141,453,310...141,466,146 		JBrowse link
G Tmcc1 transmembrane and coiled-coil domain family 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TMCC1 mRNA CTD PMID:19167446 NCBI chr 4:149,069,252...149,239,585
Ensembl chr 4:149,069,260...149,239,620 		JBrowse link
G Tmed8 transmembrane p24 trafficking protein family member 8 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TMED8 mRNA CTD PMID:19167446 NCBI chr 6:106,806,973...106,841,271
Ensembl chr 6:106,810,420...106,843,216 		JBrowse link
G Tmem106c transmembrane protein 106C multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TMEM106C mRNA CTD PMID:19167446 NCBI chr 7:129,088,468...129,094,128
Ensembl chr 7:129,088,498...129,094,130 		JBrowse link
G Tmem164 transmembrane protein 164 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TMEM164 mRNA CTD PMID:19167446 NCBI chr  X:106,288,019...106,448,642
Ensembl chr  X:106,289,371...106,448,640 		JBrowse link
G Tmem237 transmembrane protein 237 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TMEM237 mRNA CTD PMID:19167446 NCBI chr 9:60,533,348...60,569,253
Ensembl chr 9:60,535,233...60,572,567 		JBrowse link
G Tmem38b transmembrane protein 38B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TMEM38B mRNA CTD PMID:19167446 NCBI chr 5:68,460,304...68,496,026
Ensembl chr 5:68,460,304...68,496,025 		JBrowse link
G Tmem45b transmembrane protein 45b multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TMEM45B mRNA CTD PMID:19167446 NCBI chr 8:29,865,276...29,910,453
Ensembl chr 8:29,865,278...29,910,453 		JBrowse link
G Tmem64 transmembrane protein 64 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TMEM64 mRNA CTD PMID:19167446 NCBI chr 5:28,698,947...28,745,384
Ensembl chr 5:28,698,918...28,745,330 		JBrowse link
G Tmem65 transmembrane protein 65 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TMEM65 mRNA CTD PMID:19167446 NCBI chr 7:90,336,997...90,378,930
Ensembl chr 7:90,274,142...90,379,474 		JBrowse link
G Tmem97 transmembrane protein 97 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TMEM97 mRNA CTD PMID:19167446 NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730 		JBrowse link
G Tmpo thymopoietin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TMPO mRNA CTD PMID:19167446 NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727 		JBrowse link
G Tmprss3 transmembrane serine protease 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TMPRSS3 mRNA CTD PMID:19167446 NCBI chr20:9,254,102...9,273,808
Ensembl chr20:9,254,109...9,274,363 		JBrowse link
G Tmsb15b2 thymosin beta 15B2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TMSB15A mRNA CTD PMID:19167446 NCBI chr  X:100,298,705...100,300,820
Ensembl chr  X:100,298,514...100,300,886 		JBrowse link
G Tmt1a thiol methyltransferase 1A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TMT1A mRNA CTD PMID:19167446 NCBI chr 7:131,452,099...131,460,154
Ensembl chr 7:131,451,641...131,460,154 		JBrowse link
G Tmtc2 transmembrane O-mannosyltransferase targeting cadherins 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TMTC2 mRNA CTD PMID:19167446 NCBI chr 7:40,392,377...40,806,685
Ensembl chr 7:40,394,220...40,807,298 		JBrowse link
G Tnf tumor necrosis factor decreases secretion ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased secretion of TNF protein CTD PMID:29740324 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip1 TNF alpha induced protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TNFAIP1 mRNA CTD PMID:19167446 NCBI chr10:63,417,774...63,432,466
Ensembl chr10:63,417,775...63,432,466 		JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TNFRSF12A mRNA CTD PMID:19167446 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045 		JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TNFRSF21 mRNA CTD PMID:19167446 NCBI chr 9:17,879,156...17,954,085
Ensembl chr 9:17,879,156...17,954,085 		JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TOP2A mRNA CTD PMID:19167446 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TOPBP1 mRNA CTD PMID:19167446 NCBI chr 8:103,887,805...103,931,662
Ensembl chr 8:103,887,865...103,931,674 		JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TP53INP1 mRNA CTD PMID:19167446 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968 		JBrowse link
G Tpd52 tumor protein D52 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TPD52 mRNA CTD PMID:19167446 NCBI chr 2:92,735,365...92,816,079
Ensembl chr 2:92,735,620...92,816,622 		JBrowse link
G Tpd52l1 TPD52 like 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TPD52L1 mRNA CTD PMID:19167446 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109 		JBrowse link
G Tpi1 triosephosphate isomerase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TPI1 mRNA CTD PMID:19167446 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541 		JBrowse link
G Tpm1 tropomyosin 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TPM1 mRNA CTD PMID:19167446 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802 		JBrowse link
G Tpx2 TPX2, microtubule nucleation factor multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TPX2 mRNA CTD PMID:19167446 NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468 		JBrowse link
G Trerf1 transcriptional regulating factor 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TRERF1 mRNA CTD PMID:19167446 NCBI chr 9:13,631,619...13,858,326
Ensembl chr 9:13,634,126...13,857,029 		JBrowse link
G Trib1 tribbles pseudokinase 1 multiple interactions
decreases expression		 ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TRIB1 mRNA
2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of TRIB1 mRNA		 CTD PMID:19167446 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731 		JBrowse link
G Trim59 tripartite motif-containing 59 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TRIM59 mRNA CTD PMID:19167446 NCBI chr 2:153,269,210...153,281,185
Ensembl chr 2:153,268,584...153,281,031 		JBrowse link
G Trip13 thyroid hormone receptor interactor 13 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TRIP13 mRNA CTD PMID:19167446 NCBI chr 1:29,357,093...29,402,078
Ensembl chr 1:29,357,130...29,402,074 		JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TSC22D3 mRNA CTD PMID:19167446 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861 		JBrowse link
G Tsn translin multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TSN mRNA CTD PMID:19167446 NCBI chr13:29,366,405...29,377,251
Ensembl chr13:29,364,110...29,377,599 		JBrowse link
G Tspan31 tetraspanin 31 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TSPAN31 mRNA CTD PMID:19167446 NCBI chr 7:62,889,552...62,892,428
Ensembl chr 7:62,889,552...62,898,388 		JBrowse link
G Tspyl1 TSPY-like 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TSPYL1 mRNA CTD PMID:19167446 NCBI chr20:38,082,003...38,084,562
Ensembl chr20:38,081,951...38,084,554
Ensembl chr20:38,081,951...38,084,554 		JBrowse link
G Ttc39b tetratricopeptide repeat domain 39B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TTC39B mRNA CTD PMID:19167446 NCBI chr 5:97,603,329...97,708,103
Ensembl chr 5:97,609,392...97,736,270 		JBrowse link
G Ttk Ttk protein kinase multiple interactions
increases expression		 ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TTK mRNA
2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased expression of TTK mRNA		 CTD PMID:19167446 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651 		JBrowse link
G Tubb2a tubulin, beta 2A class IIa multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TUBB2A mRNA CTD PMID:19167446 NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714 		JBrowse link
G Tubb4b tubulin, beta 4B class IVb multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TUBB4B mRNA CTD PMID:19167446 NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296 		JBrowse link
G Tubb5 tubulin, beta 5 class I multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TUBB mRNA CTD PMID:19167446 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940 		JBrowse link
G Tubd1 tubulin, delta 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TUBD1 mRNA CTD PMID:19167446 NCBI chr10:71,367,936...71,391,387
Ensembl chr10:71,368,133...71,391,266 		JBrowse link
G Tubg1 tubulin, gamma 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TUBG1 mRNA CTD PMID:19167446 NCBI chr10:86,052,845...86,059,436
Ensembl chr10:86,052,743...86,059,433 		JBrowse link
G Tubgcp4 tubulin gamma complex component 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TUBGCP4 mRNA CTD PMID:19167446 NCBI chr 3:108,141,081...108,172,207
Ensembl chr 3:108,141,625...108,169,437 		JBrowse link
G Tuft1 tuftelin 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TUFT1 mRNA CTD PMID:19167446 NCBI chr 2:182,259,457...182,306,296
Ensembl chr 2:182,260,398...182,306,192 		JBrowse link
G Tulp4 TUB like protein 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TULP4 mRNA CTD PMID:19167446 NCBI chr 1:46,682,416...46,813,167
Ensembl chr 1:46,682,863...46,809,688 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TWIST1 mRNA CTD PMID:19167446 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
G Tyms thymidylate synthetase multiple interactions
increases expression		 ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TYMS mRNA
2,3-bis(3'-hydroxybenzyl)butyrolactone results in increased expression of TYMS mRNA		 CTD PMID:19167446 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G Ube2b ubiquitin-conjugating enzyme E2B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of UBE2B mRNA CTD PMID:19167446 NCBI chr10:36,248,434...36,263,379
Ensembl chr10:36,248,438...36,264,665 		JBrowse link
G Ube2h ubiquitin-conjugating enzyme E2H multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of UBE2H mRNA CTD PMID:19167446 NCBI chr 4:58,834,674...58,930,156
Ensembl chr 4:58,834,674...58,930,156 		JBrowse link
G Ube2j1 ubiquitin-conjugating enzyme E2, J1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of UBE2J1 mRNA CTD PMID:19167446 NCBI chr 5:47,422,476...47,441,476
Ensembl chr 5:47,422,587...47,441,461 		JBrowse link
G Ube2ql1 ubiquitin conjugating enzyme E2 QL1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of UBE2QL1 mRNA CTD PMID:19167446 NCBI chr 1:33,548,814...33,589,174
Ensembl chr 1:33,548,814...33,589,174 		JBrowse link
G Ube2t ubiquitin-conjugating enzyme E2T multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of UBE2T mRNA CTD PMID:19167446 NCBI chr13:46,403,352...46,413,854
Ensembl chr13:46,403,375...46,414,835 		JBrowse link
G Ube2w ubiquitin-conjugating enzyme E2W multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of UBE2W mRNA CTD PMID:19167446 NCBI chr 5:2,690,742...2,754,491
Ensembl chr 5:2,690,763...2,814,965 		JBrowse link
G Ubr7 ubiquitin protein ligase E3 component n-recognin 7 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of UBR7 mRNA CTD PMID:19167446 NCBI chr 6:121,898,613...121,918,480
Ensembl chr 6:121,898,623...121,918,477 		JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of UCHL5 mRNA CTD PMID:19167446 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502 		JBrowse link
G Uck2 uridine-cytidine kinase 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of UCK2 mRNA CTD PMID:19167446 NCBI chr13:79,380,807...79,438,121
Ensembl chr13:79,383,846...79,438,352 		JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of UHRF1 mRNA CTD PMID:19167446 NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631 		JBrowse link
G Ung uracil-DNA glycosylase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of UNG mRNA CTD PMID:19167446 NCBI chr12:42,485,276...42,494,217
Ensembl chr12:42,485,276...42,494,206 		JBrowse link
G Upf3b UPF3B, regulator of nonsense mediated mRNA decay multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of UPF3B mRNA CTD PMID:19167446 NCBI chr  X:116,335,308...116,353,332
Ensembl chr  X:116,335,308...116,353,236 		JBrowse link
G Usp1 ubiquitin specific peptidase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of USP1 mRNA CTD PMID:19167446 NCBI chr 5:113,587,564...113,598,934
Ensembl chr 5:113,587,564...113,598,932 		JBrowse link
G Usp3 ubiquitin specific peptidase 3 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of USP3 mRNA CTD PMID:19167446 NCBI chr 8:67,078,249...67,154,109
Ensembl chr 8:67,079,927...67,154,111 		JBrowse link
G Ust uronyl-2-sulfotransferase multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of UST mRNA CTD PMID:19167446 NCBI chr 1:2,666,983...2,962,276
Ensembl chr 1:2,669,592...2,962,044 		JBrowse link
G Vars2 valyl-tRNA synthetase 2, mitochondrial multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of VARS2 mRNA CTD PMID:19167446 NCBI chr20:3,077,132...3,087,994
Ensembl chr20:3,077,132...3,087,994 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO 2,3-bis(3'-hydroxybenzyl)butyrolactone inhibits the reaction [Estradiol results in increased secretion of VEGFA protein]; [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of VEGFA mRNA CTD PMID:17289903 PMID:19167446 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of VKORC1 mRNA CTD PMID:19167446 NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008 		JBrowse link
G Vrk1 VRK serine/threonine kinase 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of VRK1 mRNA CTD PMID:19167446 NCBI chr 6:124,914,770...124,981,508
Ensembl chr 6:124,914,855...124,981,436 		JBrowse link
G Wdhd1 WD repeat and HMG-box DNA binding protein 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of WDHD1 mRNA CTD PMID:19167446 NCBI chr15:20,478,310...20,523,106
Ensembl chr15:20,489,291...20,523,096 		JBrowse link
G Wdr54 WD repeat domain 54 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of WDR54 mRNA CTD PMID:19167446 NCBI chr 4:115,654,968...115,677,979
Ensembl chr 4:115,654,968...115,661,562 		JBrowse link
G Wdr76 WD repeat domain 76 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of WDR76 mRNA CTD PMID:19167446 NCBI chr 3:108,456,784...108,491,528
Ensembl chr 3:108,456,815...108,490,840 		JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of WIPI1 mRNA CTD PMID:19167446 NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846 		JBrowse link
G Wiz WIZ zinc finger multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of WIZ mRNA CTD PMID:19167446 NCBI chr 7:11,366,837...11,395,279
Ensembl chr 7:11,367,035...11,395,490 		JBrowse link
G Ypel2 yippee-like 2 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of YPEL2 mRNA CTD PMID:19167446 NCBI chr10:71,746,308...71,803,843
Ensembl chr10:71,746,311...71,803,911 		JBrowse link
G Ypel5 yippee-like 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of YPEL5 mRNA CTD PMID:19167446 NCBI chr 6:22,656,284...22,671,741
Ensembl chr 6:22,656,285...22,671,691 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of YWHAE mRNA CTD PMID:19167446 NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589 		JBrowse link
G Zbtb26 zinc finger and BTB domain containing 26 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZBTB26 mRNA CTD PMID:19167446 NCBI chr 3:21,195,319...21,207,925
Ensembl chr 3:21,195,319...21,207,942 		JBrowse link
G Zbtb4 zinc finger and BTB domain containing 4 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZBTB4 mRNA CTD PMID:19167446 NCBI chr10:54,480,698...54,501,492
Ensembl chr10:54,485,071...54,501,492 		JBrowse link
G Zc2hc1a zinc finger, C2HC-type containing 1A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZC2HC1A mRNA CTD PMID:19167446 NCBI chr 2:94,287,352...94,324,655
Ensembl chr 2:94,287,354...94,324,882 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZC3H12A mRNA CTD PMID:19167446 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
G Zdhhc7 zinc finger DHHC-type palmitoyltransferase 7 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZDHHC7 mRNA CTD PMID:19167446 NCBI chr19:48,139,309...48,156,673
Ensembl chr19:48,139,527...48,156,673 		JBrowse link
G Zfand2a zinc finger AN1-type containing 2A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZFAND2A mRNA CTD PMID:19167446 NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677 		JBrowse link
G Zfp277 zinc finger protein 277 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZNF277 mRNA CTD PMID:19167446 NCBI chr 6:57,383,454...57,512,785
Ensembl chr 6:57,383,951...57,512,765 		JBrowse link
G Zfp292 zinc finger protein 292 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZNF292 mRNA CTD PMID:19167446 NCBI chr 5:49,384,177...49,468,177
Ensembl chr 5:49,387,893...49,468,265 		JBrowse link
G Zfp354a zinc finger protein 354A multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZNF354A mRNA CTD PMID:19167446 NCBI chr10:35,396,242...35,408,069
Ensembl chr10:35,396,231...35,408,068 		JBrowse link
G Zfp367 zinc finger protein 367 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ZNF367 mRNA CTD PMID:19167446 NCBI chr17:965,161...984,290
Ensembl chr17:965,161...984,287 		JBrowse link
G Zfp467 zinc finger protein 467 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZNF467 mRNA CTD PMID:19167446 NCBI chr 4:77,385,752...77,394,709
Ensembl chr 4:77,385,758...77,392,229 		JBrowse link
G Zfp641 zinc finger protein 641 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZNF641 mRNA CTD PMID:19167446 NCBI chr 7:129,434,576...129,444,847
Ensembl chr 7:129,434,576...129,444,644 		JBrowse link
G Zfp703 zinc finger protein 703 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ZNF703 mRNA CTD PMID:19167446 NCBI chr16:65,076,507...65,080,677
Ensembl chr16:65,076,507...65,080,677 		JBrowse link
G Zfyve1 zinc finger FYVE-type containing 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZFYVE1 mRNA CTD PMID:19167446 NCBI chr 6:103,184,938...103,234,111
Ensembl chr 6:103,184,938...103,234,039 		JBrowse link
G Zkscan1 zinc finger with KRAB and SCAN domains 1 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZKSCAN1 mRNA CTD PMID:19167446 NCBI chr12:16,966,287...16,987,680
Ensembl chr12:16,966,654...16,983,865 		JBrowse link
G Zmym5 zinc finger MYM-type containing 5 multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZMYM5 mRNA CTD PMID:19167446 NCBI chr15:30,920,479...30,941,249
Ensembl chr15:30,923,241...30,941,240 		JBrowse link
G Zwilch zwilch kinetochore protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ZWILCH mRNA CTD PMID:19167446 NCBI chr 8:64,638,401...64,670,911
Ensembl chr 8:64,637,672...64,675,916 		JBrowse link
G Zwint ZW10 interacting kinetochore protein multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ZWINT mRNA CTD PMID:19167446 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957 		JBrowse link
G Zxdb zinc finger, X-linked, duplicated B multiple interactions ISO [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZXDB mRNA CTD PMID:19167446 NCBI chr  X:59,700,765...59,706,737
Ensembl chr  X:59,701,178...59,703,871
Ensembl chr  X:59,701,178...59,703,871 		JBrowse link
etoposide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A affects response to substance
multiple interactions
increases expression		 ISO ABCB1 exon polymorphism affects the susceptibility to Etoposide
[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [Celecoxib results in decreased expression of ABCB1] which results in increased susceptibility to Etoposide
Etoposide results in increased expression of ABCB1 mRNA; Etoposide results in increased expression of ABCB1 protein		 CTD PMID:12969965 PMID:15239124 PMID:19047049 PMID:19562670 PMID:27570640 More... NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects response to substance
multiple interactions
increases expression
decreases uptake
decreases response to substance		 ISO ABCC1 protein affects the susceptibility to Etoposide
Glucose inhibits the reaction [Sodium Azide inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]]; Sodium Azide inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]; Verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Verapamil inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]
Etoposide results in increased expression of ABCC1 mRNA
ABCC1 protein results in decreased susceptibility to Etoposide; ABCC1 results in decreased susceptibility to Etoposide
[GCLC protein co-treated with GCLM protein] promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; [MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Etoposide; GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; hesperetin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; naringenin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Resveratrol inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Silymarin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Tocopherols inhibits the reaction [ABCC1 protein affects the export of Etoposide]; verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]		 CTD PMID:7954421 PMID:8968083 PMID:9334814 PMID:10348353 PMID:10856430 More... NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects transport
multiple interactions		 ISO ABCC2 protein affects the transport of Etoposide
Probenecid promotes the reaction [ABCC2 protein affects the transport of Etoposide]		 CTD PMID:15751272 PMID:15849751 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases response to substance ISO ABCC3 protein results in decreased susceptibility to Etoposide CTD PMID:15884115 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO [ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Etoposide; ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide] CTD PMID:21712253 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression ISO Etoposide results in increased expression of ABHD4 mRNA CTD PMID:25270620 NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966 		JBrowse link
G Abra actin-binding Rho activating protein increases expression ISO Etoposide results in increased expression of ABRA mRNA CTD PMID:29397400 NCBI chr 7:72,970,187...72,974,255
Ensembl chr 7:72,970,186...72,974,255 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain affects response to substance ISO ACADM protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147 		JBrowse link
G Ace2 angiotensin converting enzyme 2 increases expression
decreases expression		 ISO
EXP		 Etoposide results in increased expression of ACE2 mRNA
Etoposide results in decreased expression of ACE2 mRNA		 CTD PMID:29397400 PMID:32808185 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Aco1 aconitase 1 increases expression ISO Etoposide results in increased expression of ACO1 mRNA CTD PMID:25270620 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 affects response to substance ISO ACSL3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627 		JBrowse link
G Acta1 actin, alpha 1, skeletal muscle decreases expression ISO Etoposide results in decreased expression of ACTA1 mRNA CTD PMID:29397400 NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742 		JBrowse link
G Agrn agrin increases expression ISO Etoposide results in increased expression of AGRN mRNA CTD PMID:17374387 NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003 		JBrowse link
G Ahcyl1 adenosylhomocysteinase-like 1 affects response to substance ISO AHCYL1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:195,294,149...195,328,586
Ensembl chr 2:195,294,153...195,345,815 		JBrowse link
G Ahi1 Abelson helper integration site 1 increases expression ISO Etoposide results in increased expression of AHI1 protein alternative form CTD PMID:19379585 NCBI chr 1:15,762,485...15,891,213
Ensembl chr 1:15,762,462...15,891,041 		JBrowse link
G Akap12 A-kinase anchoring protein 12 affects response to substance ISO AKAP12 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases response to substance
increases phosphorylation
multiple interactions		 ISO AKT1 protein modified form results in increased susceptibility to Etoposide
Etoposide results in increased phosphorylation of AKT1 protein
Etoposide results in increased phosphorylation of and results in increased activity of AKT1 protein; NFKB1 protein affects the reaction [Etoposide results in increased phosphorylation of AKT1 protein]; pepstatin inhibits the reaction [AKT1 protein modified form results in increased susceptibility to Etoposide]; PTEN protein inhibits the reaction [Etoposide results in increased phosphorylation of and results in increased activity of AKT1 protein]		 CTD PMID:17699715 PMID:17935137 PMID:23396362 PMID:27769712 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alad aminolevulinate dehydratase multiple interactions ISO [Cyclophosphamide co-treated with Carmustine co-treated with Etoposide] results in decreased activity of ALAD protein CTD PMID:19162187 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression ISO Etoposide results in increased expression of ALAS1 mRNA CTD PMID:25270620 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression
multiple interactions		 ISO Etoposide results in increased expression of ALDH1A1 mRNA; Etoposide results in increased expression of ALDH1A1 protein
FTL protein affects the reaction [Etoposide results in increased expression of ALDH1A1 protein]		 CTD PMID:33969609 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 affects response to substance ISO ALDH3A1 protein affects the susceptibility to Etoposide CTD PMID:15905174 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C affects response to substance
multiple interactions		 ISO ALDOC protein affects the susceptibility to Etoposide
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ALDOC protein		 CTD PMID:16217747 PMID:29733421 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Alpg alkaline phosphatase, germ cell affects response to substance ISO ALPG protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:87,748,721...87,761,500
Ensembl chr 9:87,753,648...87,757,836 		JBrowse link
G Alpp alkaline phosphatase, placental affects response to substance ISO ALPP protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606 		JBrowse link
G Ank1 ankyrin 1 increases expression ISO Etoposide results in increased expression of ANK1 mRNA CTD PMID:29397400 NCBI chr16:68,876,294...69,054,963
Ensembl chr16:68,877,504...69,054,759 		JBrowse link
G Ankrd10 ankyrin repeat domain 10 decreases expression ISO Etoposide results in decreased expression of ANKRD10 mRNA CTD PMID:21527772 NCBI chr16:77,866,489...77,889,745
Ensembl chr16:77,864,261...77,889,745 		JBrowse link
G Ankrd27 ankyrin repeat domain 27 decreases expression ISO Etoposide results in decreased expression of ANKRD27 mRNA CTD PMID:25270620 NCBI chr 1:88,251,216...88,303,615
Ensembl chr 1:88,251,226...88,303,615 		JBrowse link
G Ankrd28 ankyrin repeat domain 28 affects response to substance ISO ANKRD28 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:6,918,487...7,050,244
Ensembl chr16:6,914,336...7,050,249 		JBrowse link
G Anxa4 annexin A4 increases expression ISO Etoposide results in increased expression of ANXA4 mRNA CTD PMID:17374387 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161 		JBrowse link
G Anxa7 annexin A7 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ANXA7 protein CTD PMID:29733421 NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO Etoposide results in increased expression of APAF1 mRNA CTD PMID:25270620 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 decreases response to substance ISO APEX1 protein results in decreased susceptibility to Etoposide CTD PMID:20856196 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Aplp1 amyloid beta precursor like protein 1 decreases expression ISO Etoposide results in decreased expression of APLP1 mRNA CTD PMID:25270620 NCBI chr 1:85,696,880...85,707,215
Ensembl chr 1:85,696,882...85,707,155 		JBrowse link
G Apol2 apolipoprotein L2 increases expression ISO Etoposide results in increased expression of APOL8 mRNA CTD PMID:25270620 NCBI chr 7:109,331,367...109,338,632
Ensembl chr 7:109,331,392...109,338,558 		JBrowse link
G Aqp1 aquaporin 1 decreases expression ISO Etoposide results in decreased expression of AQP1 mRNA CTD PMID:25270620 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Ar androgen receptor multiple interactions
increases degradation		 ISO calpain inhibitor 2 inhibits the reaction [Etoposide results in increased degradation of AR protein]; CAST inhibits the reaction [Etoposide results in increased degradation of AR protein]; Etoposide inhibits the reaction [Androgens results in increased activity of AR protein]; Etoposide inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18726991 PMID:28377212 PMID:30818834 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Areg amphiregulin increases expression
decreases expression		 ISO Etoposide results in increased expression of AREG mRNA; Etoposide results in increased expression of AREG protein
Etoposide results in decreased expression of AREG mRNA		 CTD PMID:15228094 PMID:25270620 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Arg2 arginase 2 decreases expression ISO Etoposide results in decreased expression of ARG2 mRNA CTD PMID:29397400 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases expression ISO Etoposide results in increased expression of ARHGDIB mRNA CTD PMID:21527772 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658 		JBrowse link
G Arih1 ariadne RBR E3 ubiquitin protein ligase 1 increases response to substance ISO ARIH1 mutant form results in increased susceptibility to Etoposide CTD PMID:25624349 NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245 		JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 increases response to substance
decreases expression		 ISO ARL6IP5 protein results in increased susceptibility to Etoposide
Etoposide results in decreased expression of ARL6IP5		 CTD PMID:19492242 NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO ARNT protein affects the reaction [Etoposide results in increased expression of FTL protein] CTD PMID:33969609 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580 		JBrowse link
G Arsa arylsulfatase A decreases expression ISO Etoposide results in decreased expression of ARSA mRNA CTD PMID:25270620 NCBI chr 7:120,542,788...120,547,577
Ensembl chr 7:120,543,362...120,548,783 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 affects response to substance ISO ASAH1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO Etoposide results in increased phosphorylation of and results in increased activity of ATF2 protein CTD PMID:12663670 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Atf4 activating transcription factor 4 decreases expression ISO Etoposide results in decreased expression of ATF4 mRNA CTD PMID:25270620 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases phosphorylation		 ISO Etoposide results in increased phosphorylation of and results in increased activity of ATM protein
Etoposide results in increased phosphorylation of ATM protein
Etoposide results in increased phosphorylation of and affects the localization of ATM protein; pifithrin inhibits the reaction [Etoposide results in increased phosphorylation of and affects the localization of ATM protein]		 CTD PMID:22242153 PMID:26259609 PMID:37451322 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atp13a4 ATPase 13A4 decreases expression ISO Etoposide results in decreased expression of ATP13A4 mRNA CTD PMID:25270620 NCBI chr11:71,222,196...71,359,933
Ensembl chr11:71,226,161...71,359,933 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 affects response to substance ISO ATP1A1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 decreases expression ISO Etoposide results in decreased expression of ATP1A2 mRNA CTD PMID:29397400 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544 		JBrowse link
G Atp1b4 ATPase Na+/K+ transporting family member beta 4 increases expression ISO Etoposide results in increased expression of ATP1B4 mRNA CTD PMID:29397400 NCBI chr  X:117,087,284...117,108,023
Ensembl chr  X:117,057,423...117,108,020 		JBrowse link
G Atp5me ATP synthase membrane subunit e multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of ATP5ME protein CTD PMID:29733421 NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013 		JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP decreases expression ISO Etoposide results in decreased expression of ATP5PO protein CTD PMID:29733421 NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592 		JBrowse link
G Atp6v0a4 ATPase H+ transporting V0 subunit a4 affects response to substance ISO ATP6V0A4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:66,760,163...66,842,126
Ensembl chr 4:66,760,159...66,842,110 		JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A multiple interactions
decreases expression		 ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ATP6V1A protein
Etoposide results in decreased expression of ATP6V1A protein		 CTD PMID:29733421 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694 		JBrowse link
G Atp7a ATPase copper transporting alpha decreases response to substance ISO ATP7A protein results in decreased susceptibility to Etoposide CTD PMID:17510416 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Atr ATR serine/threonine kinase increases phosphorylation ISO Etoposide results in increased phosphorylation of ATR protein CTD PMID:22242153 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Atxn1 ataxin 1 decreases expression ISO Etoposide results in decreased expression of ATXN1 mRNA CTD PMID:24211769 NCBI chr17:18,737,491...19,142,360
Ensembl chr17:18,737,533...19,142,360 		JBrowse link
G Aurka aurora kinase A decreases expression ISO Etoposide results in decreased expression of AURKA mRNA CTD PMID:25270620 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390 		JBrowse link
G Avpi1 arginine vasopressin-induced 1 affects response to substance ISO AVPI1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:240,930,236...240,936,154
Ensembl chr 1:240,930,236...240,936,154 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A increases expression ISO Etoposide results in increased expression of AVPR1A mRNA CTD PMID:29397400 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215 		JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO Etoposide results in increased expression of AXL mRNA CTD PMID:21527772 NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265 		JBrowse link
G Bace2 beta-secretase 2 affects response to substance ISO BACE2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr11:36,707,447...36,789,550
Ensembl chr11:36,707,458...36,789,546 		JBrowse link
G Bag2 BAG cochaperone 2 affects response to substance ISO BAG2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:35,970,033...35,980,677
Ensembl chr 9:35,970,033...35,980,721 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases activity
increases response to substance
affects response to substance
multiple interactions
affects expression		 ISO Etoposide results in increased activity of BAK1 protein
BAK1 protein results in increased susceptibility to Etoposide
BAK1 protein affects the susceptibility to Etoposide
nimesulide inhibits the reaction [Etoposide results in increased activity of BAK1 protein]
Etoposide affects the expression of BAK1 protein		 CTD PMID:15215046 PMID:16077961 PMID:17688235 PMID:21745461 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor affects response to substance ISO BAMBI protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
decreases folding
affects response to substance		 ISO [ABT-737 co-treated with Etoposide] affects the folding of and results in increased activity of BAX protein; [Cisplatin co-treated with Etoposide] affects the localization of BAX protein; [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of BAX protein; [IL4 protein co-treated with VCAM1 protein] inhibits the reaction [Etoposide results in decreased folding of BAX protein]; [RASSF1 co-treated with Etoposide] affects the folding of and results in increased activity of BAX protein; [trigonelline co-treated with Etoposide] results in increased expression of BAX protein; [VCAM1 protein co-treated with IL4 protein] inhibits the reaction [Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]]; Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]; Etoposide results in increased activity of and affects the localization of BAX protein; Etoposide results in increased cleavage of and results in increased expression of BAX protein; Nicotine inhibits the reaction [[Cisplatin co-treated with Etoposide] affects the localization of BAX protein]; nimesulide inhibits the reaction [Etoposide results in increased activity of and affects the localization of BAX protein]
Etoposide results in increased expression of BAX mRNA; Etoposide results in increased expression of BAX protein
BAX protein affects the susceptibility to Etoposide		 CTD PMID:9815696 PMID:10620629 PMID:15131059 PMID:16077961 PMID:16120219 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression
multiple interactions
affects response to substance		 ISO Etoposide results in increased expression of BBC3 mRNA; Etoposide results in increased expression of BBC3 protein
entinostat promotes the reaction [Etoposide results in increased expression of BBC3 protein]; Etoposide promotes the reaction [entinostat results in increased expression of BBC3 protein]; Etoposide promotes the reaction [trichostatin A results in increased expression of BBC3 protein]; Etoposide promotes the reaction [UF010 compound results in increased expression of BBC3 protein]; TP53 protein modified form inhibits the reaction [Etoposide results in increased expression of BBC3 protein]; trichostatin A promotes the reaction [Etoposide results in increased expression of BBC3 protein]; UF010 compound promotes the reaction [Etoposide results in increased expression of BBC3 protein]
BBC3 protein affects the susceptibility to Etoposide		 CTD PMID:20477944 PMID:21801448 PMID:25699604 PMID:37956312 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression		 ISO [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of BCL2 protein; [Etoposide co-treated with Ciprofloxacin] results in decreased expression of BCL2 protein; [trigonelline co-treated with Etoposide] results in decreased expression of BCL2 protein; BCL2 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]; BCL2 protein results in decreased susceptibility to [Cisplatin co-treated with Etoposide]
Etoposide results in decreased expression of BCL2 mRNA; Etoposide results in decreased expression of BCL2 protein
[G(M3) Ganglioside results in increased expression of BCL2 protein] which results in decreased susceptibility to Etoposide; BCL2 protein affects the reaction [[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 mRNA]; Lithium Chloride inhibits the reaction [Etoposide results in decreased expression of BCL2 protein]		 CTD PMID:8840993 PMID:9815696 PMID:12063570 PMID:15917659 PMID:16571667 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
affects expression
decreases response to substance		 ISO [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [VCAM1 protein co-treated with IL4 protein] inhibits the reaction [Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]]; BCL2L1 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2L1 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]; BCL2L1 protein results in decreased susceptibility to [Cisplatin co-treated with Etoposide]; Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]
Etoposide affects the expression of BCL2L1 protein
BCL2L1 protein results in decreased susceptibility to Etoposide		 CTD PMID:8840993 PMID:10620629 PMID:11468182 PMID:15215046 PMID:15917659 More... NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bcl2l2 Bcl2-like 2 decreases response to substance ISO BCL2L2 results in decreased susceptibility to Etoposide CTD PMID:14973057 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624 		JBrowse link
G Bcl6b BCL6B, transcription repressor multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of BCL6B mRNA CTD PMID:29733421 NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974 		JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression
multiple interactions		 ISO Etoposide results in increased expression of BDNF mRNA
HIPK2 mutant form inhibits the reaction [Etoposide results in increased expression of BDNF mRNA]		 CTD PMID:20573984 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
increases expression
increases cleavage		 ISO CASP9 mutant form inhibits the reaction [Etoposide results in increased cleavage of BID protein]; Estradiol inhibits the reaction [Etoposide results in increased expression of BID mRNA] CTD PMID:19426747 PMID:21801448 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Bik BCL2-interacting killer increases response to substance ISO BIK protein results in increased susceptibility to Etoposide CTD PMID:16007125 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296 		JBrowse link
G Bin1 bridging integrator 1 increases response to substance ISO BIN1 protein results in increased susceptibility to Etoposide CTD PMID:21447800 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263 		JBrowse link
G Bin3 bridging integrator 3 affects response to substance ISO BIN3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:45,173,725...45,212,607
Ensembl chr15:45,173,732...45,212,604 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 affects response to substance
decreases response to substance
increases expression		 ISO BIRC2 protein affects the susceptibility to Etoposide
BIRC2 protein results in decreased susceptibility to Etoposide
Etoposide results in increased expression of BIRC2 mRNA		 CTD PMID:10815900 PMID:14970392 PMID:15050749 PMID:16217747 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases response to substance
decreases expression
multiple interactions		 ISO BIRC3 protein results in decreased susceptibility to Etoposide
Etoposide results in decreased expression of BIRC3 mRNA
[Etoposide co-treated with KN 62] results in decreased expression of BIRC3 protein		 CTD PMID:14666661 PMID:15050749 PMID:16120219 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases response to substance
increases expression		 ISO [FOXO3 protein results in decreased expression of BIRC5 protein] which results in increased susceptibility to Etoposide; BIRC5 protein inhibits the reaction [FOXO3 protein results in increased susceptibility to Etoposide]; BIRC5 protein results in decreased susceptibility to [Cisplatin co-treated with Etoposide]; Estradiol inhibits the reaction [Etoposide results in increased expression of BIRC5 mRNA]
BIRC5 protein results in decreased susceptibility to Etoposide		 CTD PMID:15917659 PMID:16322251 PMID:16364925 PMID:16382892 PMID:19211844 More... NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 decreases response to substance ISO BIRC7 protein results in decreased susceptibility to Etoposide CTD PMID:17437058 NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606 		JBrowse link
G Blm BLM RecQ like helicase decreases expression ISO Etoposide results in decreased expression of BLM mRNA CTD PMID:24211769 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO Etoposide inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Brca1 BRCA1, DNA repair associated multiple interactions
increases expression
decreases expression		 ISO BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of CDK2 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of RAD52 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of RAD54L protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC2 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC3 protein]; BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC4 protein]; pifithrin inhibits the reaction [Etoposide results in increased expression of and affects the localization of BRCA1 protein]
Etoposide results in increased expression of BRCA1 protein
Etoposide results in decreased expression of BRCA1 mRNA		 CTD PMID:15607317 PMID:16417649 PMID:26259609 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin increases expression ISO Etoposide results in increased expression of BSCL2 mRNA CTD PMID:22003191 PMID:25270620 NCBI chr 1:205,731,828...205,743,430
Ensembl chr 1:205,733,872...205,743,421 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 multiple interactions
increases expression		 ISO TRP53 protein affects the reaction [Etoposide results in increased expression of BTG2 mRNA]
TP53 promotes the reaction [Etoposide results in increased expression of BTG2 protein]
Etoposide results in increased expression of BTG2 mRNA; Etoposide results in increased expression of BTG2 protein		 CTD PMID:21382384 PMID:22003191 PMID:24211769 PMID:27358234 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Btg3 BTG anti-proliferation factor 3 decreases expression ISO Etoposide results in decreased expression of BTG3 mRNA CTD PMID:24211769 NCBI chr11:17,030,156...17,046,069
Ensembl chr11:17,030,160...17,046,170 		JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO Etoposide results in decreased expression of BUB1 mRNA CTD PMID:16120219 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650 		JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression ISO Etoposide results in decreased expression of BUB1B mRNA CTD PMID:16120219 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547 		JBrowse link
G C14h4orf19 similar to human chromosome 4 open reading frame 19 affects response to substance ISO C4ORF19 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:44,387,386...44,478,344
Ensembl chr14:44,387,393...44,478,041 		JBrowse link
G C1qbp complement C1q binding protein decreases response to substance ISO C1QBP protein results in decreased susceptibility to Etoposide CTD PMID:25354864 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649 		JBrowse link
G C2h5orf22 similar to human chromosome 5 open reading frame 22 affects response to substance ISO C5ORF22 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:61,848,790...61,864,762
Ensembl chr 2:61,849,363...61,864,738 		JBrowse link
G Cab39 calcium binding protein 39 decreases expression ISO Etoposide results in decreased expression of CAB39 mRNA CTD PMID:17374387 NCBI chr 9:86,463,095...86,524,545
Ensembl chr 9:86,463,095...86,524,544 		JBrowse link
G Cadps2 calcium dependent secretion activator 2 affects response to substance ISO CADPS2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:51,780,415...52,309,641
Ensembl chr 4:51,781,053...52,309,829 		JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions
decreases response to substance		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [CALCA protein results in decreased susceptibility to Etoposide] CTD PMID:16222118 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Calm1 calmodulin 1 increases expression ISO Etoposide results in increased expression of CALM1 mRNA CTD PMID:29397400 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227 		JBrowse link
G Card10 caspase recruitment domain family, member 10 multiple interactions
increases expression		 ISO Estradiol inhibits the reaction [Etoposide results in increased expression of CARD10 mRNA] CTD PMID:19426747 NCBI chr 7:110,330,460...110,371,551
Ensembl chr 7:110,330,408...110,359,224 		JBrowse link
G Casp2 caspase 2 increases expression
increases splicing		 ISO Etoposide results in increased expression of CASP2 mRNA alternative form
Etoposide results in increased splicing of CASP2 mRNA		 CTD PMID:14757846 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Casp3 caspase 3 affects expression
increases cleavage
multiple interactions
increases activity
increases expression		 ISO
EXP		 Etoposide affects the expression of CASP3 protein
Etoposide results in increased cleavage of CASP3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; 3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of CASP3 protein]; [Etoposide co-treated with Mifepristone] results in increased activity of CASP3 protein; [RASSF1 co-treated with Etoposide] results in increased cleavage of CASP3 protein; [STAT1 protein results in increased activity of CASP3 protein] which results in increased susceptibility to Etoposide; [trigonelline co-treated with Etoposide] results in increased cleavage of CASP3 protein; Acetylcysteine inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; Aspirin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; BCL2L1 protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; CD40LG protein inhibits the reaction [Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; CDKN1A mutant form inhibits the reaction [Aspirin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]]; Dehydroascorbic Acid promotes the reaction [Etoposide results in increased activity of CASP3 protein]; Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]; Etoposide promotes the reaction [Gold results in increased activity of CASP3 protein]; Etoposide promotes the reaction [Nanotubes, Carbon results in increased activity of CASP3 protein]; Etoposide promotes the reaction [Silver results in increased activity of CASP3 protein]; Etoposide results in increased cleavage of and results in increased activity of CASP3 protein; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; Oxygen deficiency inhibits the reaction [Etoposide results in increased expression of CASP3 protein]; palbociclib inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; pifithrin promotes the reaction [Etoposide results in increased activity of CASP3 protein]; pifithrin promotes the reaction [Etoposide results in increased cleavage of CASP3 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TMSB4X protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; Wortmannin promotes the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP3 protein]
Etoposide results in increased expression of CASP3 protein; Etoposide results in increased expression of CASP3 protein modified form
[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein; Etoposide results in increased activity of CASP3 protein
2-tert-butylhydroquinone inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP3 protein]; BCL2 protein affects the reaction [[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein]; Etoposide results in increased cleavage of and results in increased activity of CASP3 protein; HIPK2 gene mutant form promotes the reaction [Etoposide results in increased activity of CASP3 protein]; Metoclopramide inhibits the reaction [Etoposide results in increased activity of CASP3 protein]		 CTD PMID:8840993 PMID:10759716 PMID:12871656 PMID:15215046 PMID:15924153 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity		 ISO [STAT1 protein results in increased activity of CASP7 protein] which results in increased susceptibility to Etoposide; benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; palbociclib inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; pifithrin promotes the reaction [Etoposide results in increased activity of CASP7 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased activity of CASP7 protein]
2-tert-butylhydroquinone inhibits the reaction [Etoposide results in increased activity of CASP7 protein]		 CTD PMID:18056177 PMID:18649362 PMID:20299546 PMID:21801448 PMID:22275372 More... NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases response to substance
increases cleavage
increases activity
decreases response to substance		 ISO 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Etoposide results in increased activity of CASP8 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of CASP3 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of PARP1 protein]; [CASP8 co-treated with TP53] inhibits the reaction [CASP8 protein mutant form results in decreased susceptibility to Etoposide]; acetyl-leucyl-glutamyl-histidyl-aspartal inhibits the reaction [Etoposide results in increased activity of CASP8 protein]; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP9 protein]; Etoposide results in increased cleavage of and results in increased activity of CASP8 protein; Etoposide results in increased expression of and results in increased cleavage of CASP8 protein; Lithium inhibits the reaction [Etoposide results in increased activity of CASP8 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP8 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP8 protein]
CASP8 protein results in increased susceptibility to Etoposide		 CTD PMID:15475000 PMID:21745461 PMID:21801448 PMID:22010212 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases activity
affects expression		 ISO [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; [Cisplatin co-treated with Etoposide] results in increased activity of CASP9 protein; CASP8 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP9 protein]; CASP9 mutant form inhibits the reaction [Etoposide results in increased cleavage of BID protein]; Etoposide results in increased cleavage of and results in increased activity of CASP9 protein; HTATIP2 protein promotes the reaction [Etoposide results in increased activity of CASP9 protein]; MYC protein promotes the reaction [Etoposide results in increased cleavage of CASP9 protein]; Nicotine inhibits the reaction [[Cisplatin co-treated with Etoposide] results in increased activity of CASP9 protein]; nimesulide inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; TMSB4X protein inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; Wortmannin promotes the reaction [Etoposide results in increased cleavage of CASP9 protein]
Etoposide affects the expression of CASP9 protein		 CTD PMID:12925536 PMID:15215046 PMID:16364925 PMID:16799960 PMID:17935137 More... NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Casq2 calsequestrin 2 decreases expression ISO Etoposide results in decreased expression of CASQ2 mRNA CTD PMID:29397400 NCBI chr 2:189,526,003...189,582,276
Ensembl chr 2:189,525,960...189,582,267 		JBrowse link
G Cast calpastatin multiple interactions ISO CAST inhibits the reaction [Etoposide results in increased degradation of AR protein] CTD PMID:18726991 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659 		JBrowse link
G Cat catalase increases response to substance
multiple interactions
increases activity		 ISO
EXP		 CAT results in increased susceptibility to Etoposide
EPO protein inhibits the reaction [Etoposide results in increased activity of CAT protein]		 CTD PMID:21689642 PMID:25451571 PMID:29069929 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccdc51 coiled-coil domain containing 51 decreases expression ISO Etoposide results in decreased expression of CCDC51 mRNA CTD PMID:24211769 NCBI chr 8:109,722,595...109,741,478
Ensembl chr 8:109,722,557...109,741,472 		JBrowse link
G Ccdc6 coiled-coil domain containing 6 increases response to substance
decreases response to substance		 ISO CCDC6 results in increased susceptibility to Etoposide
CCDC6 results in decreased susceptibility to Etoposide		 CTD PMID:22363533 PMID:22655027 NCBI chr20:18,432,177...18,528,186
Ensembl chr20:18,433,695...18,528,658 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO Etoposide results in increased expression of CCL3 protein CTD PMID:10540334 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccn2 cellular communication network factor 2 increases expression ISO Etoposide results in increased expression of CCN2 mRNA CTD PMID:29397400 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression		 ISO Etoposide affects the expression of and affects the localization of CCNA2 protein
Etoposide results in decreased expression of CCNA2 mRNA; Etoposide results in decreased expression of CCNA2 protein		 CTD PMID:16120219 PMID:17390037 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Etoposide results in decreased expression of CCNB1 mRNA; Etoposide results in decreased expression of CCNB1 protein CTD PMID:16120219 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnd1 cyclin D1 increases expression ISO Etoposide results in increased expression of CCND1 mRNA CTD PMID:16120219 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccng1 cyclin G1 increases expression ISO Etoposide results in increased expression of CCNG1 mRNA CTD PMID:25270620 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Ccng2 cyclin G2 increases expression ISO Etoposide results in increased expression of CCNG2 mRNA CTD PMID:18754885 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830 		JBrowse link
G Ccs copper chaperone for superoxide dismutase increases expression ISO Etoposide results in increased expression of CCS mRNA CTD PMID:21527772 NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:202,113,804...202,134,915 		JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of CCT8 protein CTD PMID:29733421 NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079 		JBrowse link
G Cd274 CD274 molecule increases expression ISO Etoposide results in increased expression of CD274 protein CTD PMID:17920123 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd40lg CD40 ligand multiple interactions
decreases response to substance		 ISO CD40LG protein inhibits the reaction [Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]
CD40LG protein results in decreased susceptibility to Etoposide		 CTD PMID:16545138 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cd44 CD44 molecule affects response to substance
multiple interactions		 ISO CD44 protein affects the susceptibility to Etoposide
[[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide]; Resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide]		 CTD PMID:15215046 PMID:19047049 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) affects response to substance ISO CD55 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831 		JBrowse link
G Cd59b CD59b molecule multiple interactions ISO [Cisplatin co-treated with Etoposide] results in decreased expression of CD59 protein CTD PMID:21826740 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847 		JBrowse link
G Cdc25a cell division cycle 25A decreases expression ISO Etoposide results in decreased expression of CDC25A mRNA CTD PMID:24211769 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701 		JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO Etoposide results in decreased expression of CDC25C mRNA CTD PMID:16120219 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185 		JBrowse link
G Cdc42bpg CDC42 binding protein kinase gamma increases expression ISO Etoposide results in increased expression of CDC42BPG mRNA CTD PMID:25270620 NCBI chr 1:203,608,339...203,628,502
Ensembl chr 1:203,608,574...203,628,502 		JBrowse link
G Cdc45 cell division cycle 45 decreases expression ISO Etoposide results in decreased expression of CDC45 mRNA CTD PMID:16120219 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619 		JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO Etoposide results in decreased expression of CDC6 mRNA CTD PMID:16120219 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011 		JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
increases expression
affects response to substance		 ISO BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of CDK2 protein]; CDK2 affects the reaction [Etoposide results in increased phosphorylation of TPI1 protein]
CDK2 protein affects the susceptibility to Etoposide		 CTD PMID:16217747 PMID:16417649 PMID:20149834 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression		 ISO
EXP		 [Etoposide results in increased susceptibility to Benzo(a)pyrene] which results in increased expression of CDKN1A protein; [RASSF1 co-treated with Etoposide] results in increased expression of CDKN1A protein; CDKN1A mutant form inhibits the reaction [Aspirin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]]; CDKN1A protein affects the reaction [Etoposide results in decreased expression of UBE2C protein]; entinostat promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; Etoposide promotes the reaction [entinostat results in increased expression of CDKN1A protein]; Etoposide promotes the reaction [trichostatin A results in increased expression of CDKN1A protein]; Etoposide promotes the reaction [UF010 compound results in increased expression of CDKN1A protein]; KEAP1 protein affects the reaction [Etoposide results in increased expression of CDKN1A protein]; resveratrol inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA]; TP53 affects the reaction [Etoposide results in increased expression of CDKN1A mRNA]; TP53 promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; TP53 protein promotes the reaction [[Etoposide results in increased susceptibility to Benzo(a)pyrene] which results in increased expression of CDKN1A protein]; TP53 protein promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; trichostatin A promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; UF010 compound promotes the reaction [Etoposide results in increased expression of CDKN1A protein]
Etoposide results in increased expression of CDKN1A mRNA; Etoposide results in increased expression of CDKN1A protein
[CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the reaction [Etoposide results in increased expression of CDKN1A protein]; TRP53 affects the reaction [Etoposide results in increased expression of CDKN1A mRNA]
cordycepin inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA]; Etoposide promotes the reaction [Niacin deficiency results in increased expression of CDKN1A protein]; mithramycin A inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA]; salubrinal inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA]		 CTD PMID:14601052 PMID:16120219 PMID:16882877 PMID:17516866 PMID:21212465 More... NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
multiple interactions		 ISO Etoposide results in increased expression of CDKN1B protein
wortmannin promotes the reaction [Etoposide results in increased expression of CDKN1B protein]		 CTD PMID:17935137 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression
multiple interactions		 EXP
ISO		 Etoposide results in increased expression of CDKN2A mRNA
[CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the reaction [Etoposide results in increased expression of CDKN1A protein]; [CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the reaction [Etoposide results in increased expression of TRP53 protein]
cordycepin inhibits the reaction [Etoposide results in increased expression of CDKN2A mRNA]; mithramycin A inhibits the reaction [Etoposide results in increased expression of CDKN2A mRNA]; salubrinal inhibits the reaction [Etoposide results in increased expression of CDKN2A mRNA]		 CTD PMID:21526190 PMID:23690541 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO Etoposide results in decreased expression of CDKN3 mRNA CTD PMID:16120219 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 increases expression ISO Etoposide results in increased expression of CEACAM1 mRNA CTD PMID:17374387 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression
increases degradation		 ISO Etoposide results in decreased expression of CEBPA mRNA; Etoposide results in decreased expression of CEBPA protein
Etoposide results in increased degradation of CEBPA protein		 CTD PMID:19662097 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cebpz CCAAT/enhancer binding protein zeta decreases expression ISO Etoposide results in decreased expression of CEBPZ mRNA CTD PMID:17374387 NCBI chr 6:16,119,871...16,137,600
Ensembl chr 6:16,119,872...16,137,600 		JBrowse link
G Cel carboxyl ester lipase increases expression ISO Etoposide results in increased expression of CEL mRNA CTD PMID:21527772 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035 		JBrowse link
G Cenpf centromere protein F decreases expression ISO Etoposide results in decreased expression of CENPF mRNA CTD PMID:16120219 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669 		JBrowse link
G Cercam cerebral endothelial cell adhesion molecule increases expression ISO Etoposide results in increased expression of CERCAM mRNA CTD PMID:25270620 NCBI chr 3:13,118,150...13,155,960
Ensembl chr 3:13,142,107...13,155,956 		JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Etoposide results in increased expression of CES1D mRNA CTD PMID:25270620 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Ces2e carboxylesterase 2E increases expression ISO Etoposide results in increased expression of CES2E mRNA CTD PMID:25270620 NCBI chr19:157,447...172,822
Ensembl chr19:157,407...172,856 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO Etoposide results in increased expression of CFLAR protein CTD PMID:14601052 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 increases expression ISO Etoposide results in increased expression of CGREF1 mRNA CTD PMID:25270620 NCBI chr 6:25,431,846...25,443,853
Ensembl chr 6:25,431,799...25,443,852 		JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 decreases expression ISO Etoposide results in decreased expression of CHAC1 mRNA CTD PMID:25270620 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526 		JBrowse link
G Chaf1a chromatin assembly factor 1 subunit A decreases expression ISO Etoposide results in decreased expression of CHAF1A mRNA CTD PMID:24211769 NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654 		JBrowse link
G Chek1 checkpoint kinase 1 affects response to substance
multiple interactions		 ISO CHEK1 protein affects the susceptibility to Etoposide
TP53 protein affects the reaction [CHEK1 protein affects the susceptibility to Etoposide]		 CTD PMID:18698031 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009 		JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation
multiple interactions		 ISO Etoposide results in increased phosphorylation of CHEK2 protein
4-fluoro-2-(4-(4-(2-hydroxypropan-2-yl)pyrrolidin-3-ylamino)-6,7-dimethoxyquinazolin-2-yl)phenol inhibits the reaction [Etoposide results in increased phosphorylation of CHEK2 protein]; pifithrin inhibits the reaction [Etoposide results in increased phosphorylation of CHEK2 protein]		 CTD PMID:21186793 PMID:22242153 PMID:26259609 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Chi3l1 chitinase 3 like 1 decreases response to substance ISO CHI3L1 results in decreased susceptibility to Etoposide CTD PMID:20506295 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex decreases expression ISO Etoposide results in decreased expression of CHUK protein CTD PMID:30177839 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 decreases response to substance ISO CIAPIN1 protein results in decreased susceptibility to Etoposide CTD PMID:18389626 NCBI chr19:10,179,963...10,195,511
Ensembl chr19:10,180,100...10,195,503 		JBrowse link
G Ckm creatine kinase, M-type decreases expression ISO Etoposide results in decreased expression of CKM mRNA CTD PMID:29397400 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720 		JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1 affects response to substance ISO CKMT1B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:108,329,859...108,335,760
Ensembl chr 3:108,330,705...108,335,758 		JBrowse link
G Coa7 cytochrome c oxidase assembly factor 7 decreases expression ISO Etoposide results in decreased expression of COA7 mRNA CTD PMID:24211769 NCBI chr 5:123,069,356...123,080,942
Ensembl chr 5:123,069,371...123,080,199 		JBrowse link
G Cobl cordon-bleu WH2 repeat protein decreases expression ISO Etoposide results in decreased expression of COBL mRNA CTD PMID:25270620 NCBI chr14:86,828,137...87,060,682
Ensembl chr14:86,828,139...87,060,800 		JBrowse link
G Col15a1 collagen type XV alpha 1 chain affects response to substance ISO COL15A1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression ISO Etoposide results in decreased expression of COL4A1 mRNA CTD PMID:25270620 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Col9a3 collagen type IX alpha 3 chain affects response to substance ISO COL9A3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:167,711,776...167,734,468
Ensembl chr 3:167,711,840...167,734,465 		JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 decreases expression ISO Etoposide results in decreased expression of COX6A2 mRNA CTD PMID:29397400 NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274 		JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 affects response to substance ISO CPS1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 decreases expression ISO Etoposide results in decreased expression of CPT2 mRNA CTD PMID:24211769 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression ISO Etoposide results in increased expression of CRABP2 mRNA CTD PMID:21527772 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Etoposide results in increased expression of and results in increased phosphorylation of CREB1 protein; HIPK2 gene mutant form inhibits the reaction [Etoposide results in increased expression of and results in increased phosphorylation of CREB1 protein] CTD PMID:20573984 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crem cAMP responsive element modulator affects response to substance ISO CREM protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Crip2 cysteine-rich protein 2 increases expression ISO Etoposide results in increased expression of CRIP2 mRNA CTD PMID:25270620 NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065 		JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 affects response to substance ISO CSGALNACT1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319 		JBrowse link
G Cth cystathionine gamma-lyase affects response to substance ISO CTH protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide] CTD PMID:19047049 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO Etoposide results in decreased expression of CXCL12 mRNA; Etoposide results in decreased expression of CXCL12 protein CTD PMID:22363485 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cycs cytochrome c, somatic affects localization ISO Etoposide affects the localization of CYCS protein CTD PMID:10759716 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions		 ISO Etoposide results in increased expression of CYP1A1 mRNA; Etoposide results in increased expression of CYP1A1 protein
Etoposide promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; TP53 protein promotes the reaction [Etoposide promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]]; TP53 protein promotes the reaction [Etoposide results in increased expression of CYP1A1 protein]		 CTD PMID:29471073 PMID:31542801 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO Etoposide results in increased expression of CYP1A2 mRNA CTD PMID:31542801 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 decreases response to substance ISO CYP26A1 protein results in decreased susceptibility to Etoposide CTD PMID:15703382 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 increases expression ISO Etoposide results in increased expression of CYP27B1 mRNA CTD PMID:17716971 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241 		JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 increases expression ISO Etoposide results in increased expression of CYP2C55 mRNA CTD PMID:25270620 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases expression ISO Etoposide results in increased expression of CYP2C29 mRNA CTD PMID:25270620 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 decreases expression ISO Etoposide results in decreased expression of CYP2S1 mRNA CTD PMID:25270620 NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases methylation
increases expression
multiple interactions
affects response to substance		 ISO CYP3A4 protein results in decreased methylation of Etoposide
Etoposide results in increased expression of CYP3A4 mRNA
[Etoposide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; Cyclosporine inhibits the reaction [CYP3A4 protein results in decreased methylation of Etoposide]; Dexamethasone inhibits the reaction [CYP3A4 protein results in decreased methylation of Etoposide]; Erythromycin inhibits the reaction [CYP3A4 protein results in decreased methylation of Etoposide]; Midazolam inhibits the reaction [CYP3A4 protein results in decreased methylation of Etoposide]
CYP3A4 gene polymorphism affects the susceptibility to Etoposide; CYP3A4 protein affects the susceptibility to Etoposide		 CTD PMID:8114683 PMID:12969965 PMID:17279585 PMID:25455453 PMID:31542801 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects response to substance
decreases methylation		 ISO CYP3A5 gene polymorphism affects the susceptibility to Etoposide
CYP3A5 protein results in decreased methylation of Etoposide		 CTD PMID:8114683 PMID:12969965 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyren cell cycle regulator of NHEJ affects localization ISO Etoposide affects the localization of CYREN protein alternative form CTD PMID:24610814 NCBI chr 4:63,547,311...63,553,394
Ensembl chr 4:63,547,335...63,551,602 		JBrowse link
G Dab2 DAB adaptor protein 2 affects response to substance ISO DAB2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Dapk1 death associated protein kinase 1 increases expression
multiple interactions		 ISO Etoposide results in increased expression of DAPK1 protein; Etoposide results in increased expression of DAPK1 protein modified form
DAPK1 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein]; DAPK1 protein promotes the reaction [Etoposide results in increased expression of ETS1 protein]; DAPK1 protein promotes the reaction [Etoposide results in increased expression of TP53 protein modified form]; DAPK1 protein promotes the reaction [Etoposide results in increased expression of TP53 protein]		 CTD PMID:30177839 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Dbf4 DBF4-CDC7 kinase regulatory subunit decreases expression ISO Etoposide results in decreased expression of DBF4 mRNA CTD PMID:25270620 NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066 		JBrowse link
G Dbn1 drebrin 1 affects response to substance ISO DBN1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984 		JBrowse link
G Dcaf4 DDB1 and CUL4 associated factor 4 increases expression ISO Etoposide results in increased expression of DCAF4 mRNA CTD PMID:25270620 NCBI chr 6:103,154,847...103,180,992
Ensembl chr 6:103,154,867...103,180,982 		JBrowse link
G Dct dopachrome tautomerase affects response to substance ISO DCT protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 affects response to substance ISO DDIT4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 increases expression ISO Etoposide results in increased expression of DDR1 mRNA CTD PMID:25270620 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468 		JBrowse link
G Des desmin decreases expression ISO Etoposide results in decreased expression of DES mRNA CTD PMID:29397400 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 affects response to substance ISO DKK3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590 		JBrowse link
G Dmd dystrophin affects response to substance
decreases expression		 ISO DMD protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of DMD mRNA		 CTD PMID:16217747 PMID:29397400 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207 		JBrowse link
G Dmrt1 doublesex and mab-3 related transcription factor 1 decreases expression ISO Etoposide results in decreased expression of DMRT1 mRNA CTD PMID:25270620 NCBI chr 1:223,142,859...223,241,333
Ensembl chr 1:223,142,859...223,241,333 		JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases response to substance EXP
ISO		 DNMT1 protein results in decreased susceptibility to Etoposide CTD PMID:18314485 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases response to substance ISO DNMT3B protein results in decreased susceptibility to Etoposide CTD PMID:18314485 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dpp7 dipeptidylpeptidase 7 multiple interactions ISO Etoposide promotes the reaction [[DPP7 protein results in increased cleavage of Dipeptides] which results in increased abundance of 4-nitroaniline] CTD PMID:16725115 NCBI chr 3:8,165,091...8,169,343
Ensembl chr 3:8,165,091...8,169,355 		JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 decreases expression ISO Etoposide results in decreased expression of DPYSL2 protein CTD PMID:29733421 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829 		JBrowse link
G Dpysl4 dihydropyrimidinase-like 4 increases expression ISO Etoposide results in increased expression of DPYSL4 mRNA CTD PMID:21527772 NCBI chr 1:193,883,039...193,898,916
Ensembl chr 1:193,883,106...193,898,914 		JBrowse link
G Dusp2 dual specificity phosphatase 2 affects response to substance ISO DUSP2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499 		JBrowse link
G Dusp4 dual specificity phosphatase 4 affects response to substance
increases expression		 ISO DUSP4 protein affects the susceptibility to Etoposide
Etoposide results in increased expression of DUSP4 mRNA		 CTD PMID:16217747 PMID:29397400 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138 		JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO E2F1 protein affects the reaction [Etoposide results in increased expression of HIC1 mRNA]; Etoposide promotes the reaction [E2F1 protein binds to HIC1 promoter] CTD PMID:19491197 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G Edn1 endothelin 1 multiple interactions ISO EDN1 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Etoposide] CTD PMID:24184161 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednrb endothelin receptor type B decreases expression ISO Etoposide results in decreased expression of EDNRB mRNA CTD PMID:25270620 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Efs embryonal Fyn-associated substrate increases expression ISO Etoposide results in increased expression of EFS mRNA CTD PMID:25270620 NCBI chr15:28,392,417...28,403,016
Ensembl chr15:28,392,187...28,401,902 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO [EGF protein results in decreased expression of TOP2A protein] which results in decreased susceptibility to Etoposide CTD PMID:16969495 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfl8 EGF-like-domain, multiple 8 affects response to substance ISO EGFL8 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr20:4,132,930...4,136,024
Ensembl chr20:4,133,629...4,136,018 		JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Etoposide results in decreased expression of EGFR mRNA; Etoposide results in decreased expression of EGFR protein CTD PMID:15228094 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein increases expression ISO Etoposide results in increased expression of EI24 mRNA CTD PMID:17374387 NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571 		JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta decreases expression ISO Etoposide results in decreased expression of EIF2S2 mRNA CTD PMID:25270620 NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432 		JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A increases response to substance ISO EIF3A results in increased susceptibility to Etoposide CTD PMID:21610145 NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976 		JBrowse link
G Emp1 epithelial membrane protein 1 increases expression ISO Etoposide results in increased expression of EMP1 mRNA CTD PMID:21527772 NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904 		JBrowse link
G Emp2 epithelial membrane protein 2 affects response to substance ISO EMP2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:5,360,073...5,394,734
Ensembl chr10:5,360,073...5,394,733 		JBrowse link
G Emp3 epithelial membrane protein 3 increases expression ISO Etoposide results in increased expression of EMP3 mRNA CTD PMID:21527772 NCBI chr 1:96,388,651...96,391,946
Ensembl chr 1:96,388,652...96,391,988 		JBrowse link
G En2 engrailed homeobox 2 affects response to substance ISO EN2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:7,221,096...7,226,943
Ensembl chr 4:7,221,096...7,226,943 		JBrowse link
G Eno1 enolase 1 decreases expression ISO Etoposide results in decreased expression of ENO1 protein CTD PMID:29733421 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 decreases expression ISO Etoposide results in decreased expression of ENTPD2 mRNA CTD PMID:25270620 NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866 		JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of CTNNB1 protein] which results in decreased susceptibility to Etoposide]; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide] CTD PMID:19047049 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 affects response to substance ISO EPB41L3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression ISO Etoposide results in increased expression of EPHX1 mRNA CTD PMID:21382384 PMID:25270620 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Epm2aip1 EPM2A interacting protein 1 increases expression ISO Etoposide results in increased expression of EPM2AIP1 mRNA CTD PMID:17374387 NCBI chr 8:111,233,871...111,241,219
Ensembl chr 8:111,233,826...111,241,871 		JBrowse link
G Epo erythropoietin multiple interactions ISO EPO protein inhibits the reaction [Etoposide results in increased activity of CAT protein]; EPO protein results in increased susceptibility to [Organoplatinum Compounds co-treated with Etoposide] CTD PMID:18403296 PMID:29069929 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions
decreases expression
decreases response to substance
affects response to substance		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide]; [ERBB2 results in increased expression of ABCG2] which results in decreased susceptibility to Etoposide; ABCG2 mutant form inhibits the reaction [ERBB2 results in decreased susceptibility to Etoposide]; Curcumin analog inhibits the reaction [ERBB2 protein results in decreased susceptibility to Etoposide]
Etoposide results in decreased expression of ERBB2 mRNA
ERBB2 protein results in decreased susceptibility to Etoposide; ERBB2 results in decreased susceptibility to Etoposide
ERBB2 protein affects the susceptibility to Etoposide		 CTD PMID:10327070 PMID:15228094 PMID:21712253 PMID:25866362 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 affects response to substance
decreases expression		 ISO ERBB3 protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of ERBB3 mRNA		 CTD PMID:15228094 PMID:16217747 PMID:29397400 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 decreases expression ISO Etoposide results in decreased expression of ERBB4 mRNA CTD PMID:15228094 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Ereg epiregulin increases expression ISO Etoposide results in increased expression of EREG mRNA CTD PMID:15228094 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Ervfrd-1 endogenous retrovirus group FRD member 1, envelope affects response to substance ISO ERVFRD-1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr12:22,151,211...22,158,264
Ensembl chr12:22,151,211...22,158,264 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Etoposide inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:30818834 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 increases response to substance
multiple interactions		 ISO ESR2 protein results in increased susceptibility to Etoposide
TP53 protein inhibits the reaction [ESR2 protein results in increased susceptibility to Etoposide]		 CTD PMID:20623183 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Esrp1 epithelial splicing regulatory protein 1 affects response to substance ISO ESRP1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:24,427,611...24,482,157
Ensembl chr 5:24,428,717...24,482,062 		JBrowse link
G Esrra estrogen related receptor, alpha multiple interactions ISO Etoposide inhibits the reaction [XCT790 results in decreased activity of ESRRA protein]; Etoposide promotes the reaction [PPARGC1A protein results in increased activity of ESRRA protein] CTD PMID:30818834 NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions
increases expression		 ISO DAPK1 protein promotes the reaction [Etoposide results in increased expression of ETS1 protein]; ETS1 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein]; TP53 protein promotes the reaction [Etoposide results in increased expression of ETS1 protein] CTD PMID:30177839 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010 		JBrowse link
G Etv6 ETS variant transcription factor 6 increases response to substance
increases mutagenesis		 ISO ETV6 gene mutant form results in increased susceptibility to Etoposide
Etoposide results in increased mutagenesis of ETV6 gene		 CTD PMID:15217836 PMID:28624474 NCBI chr 4:166,849,031...167,085,211
Ensembl chr 4:166,847,686...167,084,992 		JBrowse link
G Exoc4 exocyst complex component 4 increases expression ISO Etoposide results in increased expression of EXOC4 mRNA CTD PMID:25270620 NCBI chr 4:61,807,706...62,584,316
Ensembl chr 4:61,807,761...62,585,723 		JBrowse link
G F11r F11 receptor increases expression ISO Etoposide results in increased expression of F11R mRNA CTD PMID:29397400 NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402 		JBrowse link
G F2r coagulation factor II (thrombin) receptor affects response to substance ISO F2R protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870 		JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO Etoposide results in increased expression of F3 mRNA CTD PMID:12542493 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fads3 fatty acid desaturase 3 increases expression ISO Etoposide results in increased expression of FADS3 mRNA CTD PMID:21527772 NCBI chr 1:206,685,667...206,702,538
Ensembl chr 1:206,685,894...206,704,769 		JBrowse link
G Fam171a1 family with sequence similarity 171, member A1 affects response to substance ISO FAM171A1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:75,024,582...75,148,348
Ensembl chr17:75,024,575...75,150,255 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression		 ISO 3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Etoposide results in increased expression of and affects the localization of FAS protein]; Etoposide results in increased expression of and affects the localization of FAS protein; Lithium inhibits the reaction [Etoposide results in increased expression of and affects the localization of FAS protein]
Etoposide results in increased expression of FAS mRNA
Etoposide results in increased expression of FAS mRNA; Etoposide results in increased expression of FAS protein		 CTD PMID:12513834 PMID:15475000 PMID:16192531 PMID:29397400 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand multiple interactions
increases expression
increases activity		 ISO [linsidomine results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]; [S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]; [S-Nitrosoglutathione results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]; [spermine nitric oxide complex results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]; Nitric Oxide inhibits the reaction [Etoposide results in increased activity of FASLG promoter]
Etoposide results in increased expression of FASL mRNA		 CTD PMID:10811113 PMID:12513834 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fasn fatty acid synthase increases expression ISO Etoposide results in increased expression of FASN mRNA CTD PMID:17089011 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fbl fibrillarin affects localization ISO Etoposide analog affects the localization of FBL protein CTD PMID:10942594 NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 affects response to substance ISO FDFT1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fdxr ferredoxin reductase increases expression ISO Etoposide results in increased expression of FDXR mRNA CTD PMID:17374387 NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658 		JBrowse link
G Fgf2 fibroblast growth factor 2 affects response to substance ISO FGF2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fhl1 four and a half LIM domains 1 affects response to substance ISO FHL1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:134,555,399...134,614,930
Ensembl chr  X:134,555,479...134,614,928 		JBrowse link
G Fhl2 four and a half LIM domains 2 decreases expression ISO Etoposide results in decreased expression of FHL2 mRNA CTD PMID:29397400 NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192 		JBrowse link
G Flnc filamin C increases expression ISO Etoposide results in increased expression of FLNC mRNA CTD PMID:21527772 NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases response to substance
increases expression
multiple interactions		 EXP
ISO		 FOS protein results in decreased susceptibility to Etoposide
Etoposide results in increased expression of FOS
[Etoposide co-treated with Cyclic AMP] results in increased expression of FOS mRNA; Acetylcysteine inhibits the reaction [Etoposide results in increased expression of FOS]		 CTD PMID:10711420 PMID:18314485 PMID:23824011 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Etoposide results in increased expression of FOSL1 mRNA CTD PMID:25270620 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Foxf2 forkhead box F2 affects response to substance ISO FOXF2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:32,835,730...32,842,547
Ensembl chr17:32,836,777...32,842,176 		JBrowse link
G Foxj2 forkhead box J2 decreases expression ISO Etoposide results in decreased expression of FOXJ2 mRNA CTD PMID:24211769 NCBI chr 4:156,047,043...156,073,540
Ensembl chr 4:156,046,969...156,073,518 		JBrowse link
G Foxo1 forkhead box O1 increases phosphorylation
multiple interactions		 ISO Etoposide results in increased phosphorylation of FOXO1 protein
wortmannin inhibits the reaction [Etoposide results in increased phosphorylation of FOXO1 protein]		 CTD PMID:17935137 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Foxo3 forkhead box O3 increases phosphorylation
increases response to substance
multiple interactions		 ISO Etoposide results in increased phosphorylation of FOXO3 protein
FOXO3 protein results in increased susceptibility to Etoposide
[FOXO3 protein results in decreased expression of BIRC5 protein] which results in increased susceptibility to Etoposide; BIRC5 protein inhibits the reaction [FOXO3 protein results in increased susceptibility to Etoposide]; Wortmannin inhibits the reaction [Etoposide results in increased phosphorylation of FOXO3 protein]		 CTD PMID:17935137 PMID:19211844 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions
increases expression		 ISO HIPK2 protein promotes the reaction [Etoposide results in increased expression of FTH1 mRNA] CTD PMID:20980392 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G Ftl1 ferritin light chain 1 increases expression
multiple interactions		 ISO Etoposide results in increased expression of FTL mRNA; Etoposide results in increased expression of FTL protein
1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)pyridin-2-yl)piperazine inhibits the reaction [Etoposide results in increased expression of FTL protein]; ARNT protein affects the reaction [Etoposide results in increased expression of FTL protein]; Etoposide promotes the reaction [HIF1A protein binds to FTL promoter]; FTL protein affects the reaction [Etoposide results in increased expression of ALDH1A1 protein]; FTL protein affects the reaction [Etoposide results in increased expression of KLF4 protein]; FTL protein affects the reaction [Etoposide results in increased expression of SOX2 protein]; HIF1A protein affects the reaction [Etoposide results in increased expression of FTL protein]		 CTD PMID:33969609 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725 		JBrowse link
G Fut8 fucosyltransferase 8 affects response to substance ISO FUT8 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:95,949,246...96,176,677
Ensembl chr 6:95,949,991...96,176,677 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase affects response to substance
decreases expression		 ISO FYN protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of FYN mRNA		 CTD PMID:16217747 PMID:25270620 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Fzd1 frizzled class receptor 1 decreases expression ISO Etoposide results in decreased expression of FZD1 mRNA CTD PMID:24211769 NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643 		JBrowse link
G Fzd5 frizzled class receptor 5 decreases expression ISO Etoposide results in decreased expression of FZD5 mRNA CTD PMID:25270620 NCBI chr 9:66,113,096...66,120,276
Ensembl chr 9:66,113,112...66,121,457 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases response to substance
multiple interactions
increases expression		 ISO GADD45A protein results in increased susceptibility to Etoposide
IKBKB protein inhibits the reaction [Etoposide results in increased expression of GADD45A protein]
Etoposide results in increased expression of GADD45A mRNA; Etoposide results in increased expression of GADD45A protein		 CTD PMID:19003803 PMID:21527772 PMID:29397400 PMID:30177839 PMID:31542801 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Ganab glucosidase II alpha subunit multiple interactions
decreases expression		 ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of GANAB protein
Etoposide results in decreased expression of GANAB protein		 CTD PMID:29733421 NCBI chr 1:205,793,910...205,813,704
Ensembl chr 1:205,793,895...205,813,695 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO Etoposide results in increased expression of GAPDH protein CTD PMID:29733421 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [GCLC protein co-treated with GCLM protein] promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Etoposide CTD PMID:10900222 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO [GCLC protein co-treated with GCLM protein] promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Etoposide CTD PMID:10900222 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions
increases expression		 ISO Etoposide promotes the reaction [[TP53 protein binds to GDF15 promoter] which results in increased expression of GDF15 mRNA]
[Etoposide results in increased expression of TP53 protein] which results in increased expression of GDF15 protein; Etoposide results in increased expression of GDF15 mRNA; Etoposide results in increased expression of GDF15 protein		 CTD PMID:11895857 PMID:16120219 PMID:24211769 PMID:29397400 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
increases response to substance		 ISO GJA1 protein affects the reaction [Simvastatin results in increased susceptibility to Etoposide]; Tetradecanoylphorbol Acetate affects the reaction [GJA1 protein results in increased susceptibility to Etoposide] CTD PMID:23978459 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gja5 gap junction protein, alpha 5 decreases expression ISO Etoposide results in decreased expression of GJA5 mRNA CTD PMID:29397400 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Gls2 glutaminase 2 increases expression ISO Etoposide results in increased expression of GLS2 mRNA CTD PMID:21527772 PMID:29397400 NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426 		JBrowse link
G Gpihbp1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 decreases expression ISO Etoposide results in decreased expression of GPIHBP1 mRNA CTD PMID:25270620 NCBI chr 7:107,285,584...107,288,702
Ensembl chr 7:107,285,654...107,288,702 		JBrowse link
G Gpm6b glycoprotein m6b affects response to substance ISO GPM6B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:28,057,788...28,204,409
Ensembl chr  X:28,059,450...28,204,211 		JBrowse link
G Gpnmb glycoprotein nmb increases expression ISO Etoposide results in increased expression of GPNMB mRNA CTD PMID:29397400 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367 		JBrowse link
G Gpr37 G protein-coupled receptor 37 affects response to substance ISO GPR37 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:54,138,860...54,160,927
Ensembl chr 4:54,138,870...54,161,001 		JBrowse link
G Gpsm2 G-protein signaling modulator 2 affects response to substance ISO GPSM2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:196,327,149...196,375,322
Ensembl chr 2:196,327,149...196,375,154 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Etoposide results in increased expression of GPX1 mRNA CTD PMID:29397400 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO Etoposide results in increased expression of GPX3 mRNA CTD PMID:25270620 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression ISO Etoposide results in increased expression of GRIA3 mRNA CTD PMID:25270620 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Grpel1 GrpE-like 1, mitochondrial decreases expression ISO Etoposide results in decreased expression of GRPEL1 mRNA CTD PMID:24211769 NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases activity		 ISO BCL2 protein affects the reaction [[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein]
[Etoposide results in increased activity of GSK3B protein] which results in increased activity of CASP3 protein; Etoposide results in increased activity of GSK3B protein		 CTD PMID:19408126 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance ISO GSTM1 gene polymorphism affects the susceptibility to Etoposide CTD PMID:15713801 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm4 glutathione S-transferase mu 4 affects response to substance ISO GSTM4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
decreases response to substance
affects response to substance		 ISO Curcumin inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]; Ethacrynic Acid inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]; GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide]; Sulfinpyrazone inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]; verlukast inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide]
GSTP1 gene polymorphism affects the susceptibility to Etoposide		 CTD PMID:10900222 PMID:12969965 PMID:15999103 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstt2 glutathione S-transferase theta 2 affects response to substance ISO GSTT2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288 		JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases expression
decreases response to substance
increases phosphorylation		 ISO
EXP		 Celecoxib inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein]; nimesulide inhibits the reaction [Etoposide results in increased phosphorylation of H2AX protein]; palbociclib inhibits the reaction [Etoposide results in increased expression of H2AX protein]; pifithrin promotes the reaction [Etoposide results in increased expression of H2AX protein]
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Etoposide results in increased expression of H2AX protein]; RAD54B protein affects the reaction [Etoposide results in increased expression of H2AX protein]; TOP2B protein affects the reaction [Etoposide results in increased expression of H2AX protein]
4,4'-(1,2-dimethyl-1,2-ethanediyl)bis-2,6-piperazinedione inhibits the reaction [Etoposide results in increased expression of H2AX protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Etoposide results in increased expression of H2AX protein]; Bortezomib inhibits the reaction [Etoposide results in increased expression of H2AX protein]; Razoxane inhibits the reaction [Etoposide results in increased expression of H2AX protein]
H2AX protein results in decreased susceptibility to Etoposide
Etoposide results in increased expression of H2AX protein; Etoposide results in increased expression of H2AX protein modified form		 CTD PMID:17875725 PMID:20643100 PMID:20978201 PMID:21555580 PMID:21745461 More... NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Hal histidine ammonia lyase decreases expression ISO Etoposide results in decreased expression of HAL mRNA CTD PMID:25270620 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701 		JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression
multiple interactions		 ISO Etoposide results in decreased expression of HAMP mRNA
Etoposide inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]		 CTD PMID:25270620 PMID:25633564 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Etoposide results in increased expression of HBEGF mRNA CTD PMID:15228094 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Hbp1 HMG-box transcription factor 1 decreases expression ISO Etoposide results in decreased expression of HBP1 mRNA CTD PMID:24211769 NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787 		JBrowse link
G Hdac4 histone deacetylase 4 affects response to substance ISO HDAC4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Heph hephaestin affects response to substance ISO HEPH protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:61,151,131...61,402,980
Ensembl chr  X:61,296,345...61,402,980 		JBrowse link
G Hic1 HIC ZBTB transcriptional repressor 1 multiple interactions
increases expression		 ISO E2F1 protein affects the reaction [Etoposide results in increased expression of HIC1 mRNA]; Etoposide promotes the reaction [E2F1 protein binds to HIC1 promoter] CTD PMID:19491197 NCBI chr10:60,014,520...60,019,475
Ensembl chr10:60,011,528...60,019,475 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO Etoposide promotes the reaction [HIF1A protein binds to FTL promoter]; HIF1A mutant form inhibits the reaction [Oxygen deficiency results in decreased susceptibility to Etoposide]; HIF1A protein affects the reaction [Etoposide results in increased expression of FTL protein] CTD PMID:23144690 PMID:33969609 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 increases activity
multiple interactions
decreases response to substance		 ISO Etoposide results in increased activity of HIPK2 protein
HIPK2 gene mutant form inhibits the reaction [Etoposide results in increased expression of and results in increased phosphorylation of CREB1 protein]; HIPK2 gene mutant form promotes the reaction [Etoposide results in increased activity of CASP3 protein]; HIPK2 protein promotes the reaction [Etoposide results in increased expression of FTH1 mRNA]; HIPK2 protein promotes the reaction [Etoposide results in increased expression of NQO1 mRNA]
HIPK2 results in decreased susceptibility to Etoposide
HIPK2 mutant form inhibits the reaction [Etoposide results in increased expression of BDNF mRNA]		 CTD PMID:20573984 PMID:20980392 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific decreases expression ISO Etoposide results in decreased expression of HMCES mRNA CTD PMID:25270620 NCBI chr 4:120,392,812...120,415,616
Ensembl chr 4:120,366,542...120,415,616 		JBrowse link
G Hmg20b high mobility group 20 B affects response to substance ISO HMG20B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:8,368,934...8,373,650
Ensembl chr 7:8,368,990...8,373,640 		JBrowse link
G Hmga2 high mobility group AT-hook 2 affects response to substance ISO HMGA2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Hmgb1 high mobility group box 1 increases secretion
decreases response to substance		 ISO Etoposide results in increased secretion of HMGB1 protein
HMGB1 protein results in decreased susceptibility to Etoposide		 CTD PMID:27807322 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 decreases expression ISO Etoposide results in decreased expression of HNRNPH2 protein CTD PMID:29733421 NCBI chr  X:97,780,890...97,786,846
Ensembl chr  X:97,780,785...97,787,041 		JBrowse link
G Hoxa5 homeo box A5 affects response to substance ISO HOXA5 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:81,302,341...81,306,234
Ensembl chr 4:81,302,353...81,306,234 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90AA1 protein CTD PMID:24478030 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90B1 protein CTD PMID:24478030 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 affects response to substance ISO HSPA2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287 		JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression ISO Etoposide results in increased expression of HSPE1 protein CTD PMID:29733421 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089 		JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 affects response to substance
increases response to substance
multiple interactions		 ISO HTATIP2 protein affects the susceptibility to Etoposide
HTATIP2 protein results in increased susceptibility to Etoposide
HTATIP2 protein promotes the reaction [Etoposide results in increased activity of CASP9 protein]; HTATIP2 protein promotes the reaction [Etoposide results in increased activity of PARP1 protein]		 CTD PMID:16217747 PMID:16799960 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629 		JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 affects response to substance ISO HTR4 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr18:55,765,981...55,949,921
Ensembl chr18:55,766,725...55,949,321 		JBrowse link
G Ier5 immediate early response 5 increases expression ISO Etoposide results in increased expression of IER5 mRNA CTD PMID:21527772 NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227 		JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 affects response to substance ISO IFITM1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169 		JBrowse link
G Igdcc4 immunoglobulin superfamily, DCC subclass, member 4 increases expression ISO Etoposide results in increased expression of IGDCC4 mRNA CTD PMID:25270620 NCBI chr 8:65,621,893...65,657,651
Ensembl chr 8:65,621,897...65,657,648 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor affects response to substance ISO IGF1R protein affects the susceptibility to Etoposide CTD PMID:15499378 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 affects response to substance ISO IGFBP7 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314 		JBrowse link
G Igsf11 immunoglobulin superfamily, member 11 decreases expression ISO Etoposide results in decreased expression of IGSF11 mRNA CTD PMID:25270620 NCBI chr11:61,733,139...61,884,059
Ensembl chr11:61,733,144...61,868,348 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta affects response to substance
multiple interactions
decreases expression		 ISO IKBKB protein affects the susceptibility to Etoposide
DAPK1 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein]; ETS1 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein]; IKBKB protein inhibits the reaction [Etoposide results in increased expression of GADD45A protein]; IKBKB protein promotes the reaction [Etoposide results in increased expression of MDM2 protein modified form]; IKBKB protein promotes the reaction [Etoposide results in increased expression of MDM2 protein]; TP53 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein]		 CTD PMID:20159942 PMID:30177839 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO Etoposide results in increased expression of IL1B mRNA CTD PMID:18523641 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il4 interleukin 4 decreases response to substance
multiple interactions		 ISO IL4 protein results in decreased susceptibility to Etoposide
[IL4 protein co-treated with VCAM1 protein] inhibits the reaction [Etoposide results in decreased folding of BAX protein]; [VCAM1 protein co-treated with IL4 protein] inhibits the reaction [Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]]; [VCAM1 protein co-treated with IL4 protein] results in decreased susceptibility to Etoposide		 CTD PMID:10620629 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
increases secretion		 ISO
EXP		 (4-(5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl)pyridin-2-yl)-(1-phenylethyl)amine inhibits the reaction [Etoposide results in increased expression of IL6 mRNA]; (4-(5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl)pyridin-2-yl)-(1-phenylethyl)amine inhibits the reaction [Etoposide results in increased secretion of IL6 protein]
Etoposide results in increased expression of IL6 mRNA; Etoposide results in increased expression of IL6 protein		 CTD PMID:15135310 PMID:17003255 PMID:18523641 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inka2 inka box actin regulator 2 increases expression ISO Etoposide results in increased expression of INKA2 mRNA CTD PMID:25270620 NCBI chr 2:193,185,275...193,200,643
Ensembl chr 2:193,185,275...193,200,642 		JBrowse link
G Insig1 insulin induced gene 1 affects response to substance ISO INSIG1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Ints15 integrator complex subunit 15 decreases expression ISO Etoposide results in decreased expression of INTS15 mRNA CTD PMID:24211769 NCBI chr12:11,245,045...11,260,170
Ensembl chr12:11,245,842...11,260,166 		JBrowse link
G Ireb2 iron responsive element binding protein 2 multiple interactions
decreases expression		 ISO 1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)pyridin-2-yl)piperazine inhibits the reaction [Etoposide results in decreased expression of IREB2 protein]
Etoposide results in decreased expression of IREB2 mRNA; Etoposide results in decreased expression of IREB2 protein		 CTD PMID:33969609 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611 		JBrowse link
G Irs2 insulin receptor substrate 2 affects response to substance ISO IRS2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482 		JBrowse link
G Irx4 iroquois homeobox 4 decreases expression ISO Etoposide results in decreased expression of IRX4 mRNA CTD PMID:29397400 NCBI chr 1:30,030,561...30,039,549
Ensembl chr 1:30,030,561...30,039,549 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier increases expression ISO Etoposide results in increased expression of ISG15 mRNA CTD PMID:21527772 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 affects response to substance ISO ISG20 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027 		JBrowse link
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 decreases expression ISO Etoposide results in decreased expression of ISG20L2 mRNA CTD PMID:24211769 NCBI chr 2:173,396,780...173,407,102
Ensembl chr 2:173,396,780...173,406,614 		JBrowse link
G Itga2b integrin subunit alpha 2b increases expression ISO Etoposide results in increased expression of ITGA2B mRNA CTD PMID:21527772 NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168 		JBrowse link
G Itgb3 integrin subunit beta 3 increases response to substance ISO ITGB3 protein results in increased susceptibility to Etoposide CTD PMID:21332719 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 affects response to substance ISO ITPR1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Etoposide co-treated with Cyclic AMP] results in increased expression of JUN mRNA CTD PMID:10711420 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcnab2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 affects response to substance ISO KCNAB2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:162,899,511...162,988,057
Ensembl chr 5:162,901,896...162,988,243 		JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 decreases expression ISO Etoposide results in decreased expression of KCNE3 mRNA CTD PMID:25270620 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020 		JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 decreases expression ISO Etoposide results in decreased expression of KCNN2 mRNA CTD PMID:29397400 NCBI chr18:37,817,966...38,258,347
Ensembl chr18:37,817,957...38,258,347 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases response to substance
multiple interactions
increases response to substance		 ISO KEAP1 protein results in decreased susceptibility to Etoposide
KEAP1 protein affects the reaction [Etoposide results in increased expression of CDKN1A protein]
KEAP1 mRNA results in increased susceptibility to Etoposide		 CTD PMID:22684020 PMID:26708503 PMID:27982581 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Kif1a kinesin family member 1A increases expression ISO Etoposide results in increased expression of KIF1A mRNA CTD PMID:21527772 NCBI chr 9:93,563,033...93,647,412
Ensembl chr 9:93,563,045...93,647,480 		JBrowse link
G Kif20a kinesin family member 20A decreases expression ISO Etoposide results in decreased expression of KIF20A mRNA CTD PMID:24211769 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780 		JBrowse link
G Kif23 kinesin family member 23 decreases expression ISO Etoposide results in decreased expression of KIF23 mRNA CTD PMID:25270620 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase multiple interactions
increases expression		 ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of KIT protein
Etoposide results in increased expression of KIT protein		 CTD PMID:29733421 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Klf4 KLF transcription factor 4 increases expression
multiple interactions		 ISO Etoposide results in increased expression of KLF4 mRNA; Etoposide results in increased expression of KLF4 protein
FTL protein affects the reaction [Etoposide results in increased expression of KLF4 protein]		 CTD PMID:33969609 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Klf5 KLF transcription factor 5 increases expression ISO Etoposide results in increased expression of KLF5 mRNA CTD PMID:29397400 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445 		JBrowse link
G Klf6 KLF transcription factor 6 decreases expression ISO Etoposide results in decreased expression of KLF6 mRNA CTD PMID:24211769 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570 		JBrowse link
G Klhl26 kelch-like family member 26 increases expression ISO Etoposide results in increased expression of KLHL26 mRNA CTD PMID:25270620 NCBI chr16:18,952,123...18,977,328
Ensembl chr16:18,952,234...18,977,328 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 multiple interactions ISO Etoposide inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 mRNA] CTD PMID:20601956 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
G Kmt2a lysine methyltransferase 2A increases response to substance
increases mutagenesis
increases cleavage		 ISO KMT2A gene mutant form results in increased susceptibility to Etoposide
Etoposide results in increased mutagenesis of KMT2A gene
Etoposide results in increased cleavage of KMT2A gene		 CTD PMID:14712291 PMID:24086652 PMID:28624474 NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181 		JBrowse link
G Krt19 keratin 19 increases expression ISO Etoposide results in increased expression of KRT19 mRNA CTD PMID:29397400 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt80 keratin 80 increases expression ISO Etoposide results in increased expression of KRT80 mRNA CTD PMID:21527772 NCBI chr 7:132,463,216...132,485,134
Ensembl chr 7:132,463,218...132,485,508 		JBrowse link
G Kynu kynureninase affects response to substance ISO KYNU protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G Lancl1 LanC like glutathione S-transferase 1 affects response to substance ISO LANCL1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:68,515,052...68,548,646
Ensembl chr 9:68,518,574...68,548,628 		JBrowse link
G Lap3 leucine aminopeptidase 3 decreases expression ISO Etoposide results in decreased expression of LAP3 mRNA CTD PMID:25270620 NCBI chr14:65,608,375...65,627,359
Ensembl chr14:65,608,376...65,627,359 		JBrowse link
G Lcn2 lipocalin 2 increases response to substance EXP LCN2 protein results in increased susceptibility to Etoposide CTD PMID:19860839 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Ldb3 LIM domain binding 3 decreases expression ISO Etoposide results in decreased expression of LDB3 mRNA CTD PMID:29397400 NCBI chr16:9,855,768...9,920,108
Ensembl chr16:9,855,927...9,918,532 		JBrowse link
G Lgals3 galectin 3 affects response to substance ISO LGALS3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Lgals7 galectin 7 increases expression ISO Etoposide results in increased expression of LGALS7 mRNA CTD PMID:21527772 NCBI chr 1:84,148,612...84,152,016
Ensembl chr 1:84,150,252...84,152,015 		JBrowse link
G Lhx1 LIM homeobox 1 multiple interactions
decreases expression		 ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of LHX1 mRNA
Etoposide results in decreased expression of LHX1 mRNA		 CTD PMID:29733421 NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617 		JBrowse link
G Lhx2 LIM homeobox 2 decreases expression ISO Etoposide results in decreased expression of LHX2 mRNA CTD PMID:24211769 NCBI chr 3:22,113,619...22,143,909
Ensembl chr 3:22,126,007...22,143,908 		JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO Etoposide results in increased expression of LIF mRNA CTD PMID:29397400 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Limch1 LIM and calponin homology domains 1 affects response to substance ISO LIMCH1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr14:41,112,579...41,425,001
Ensembl chr14:41,114,803...41,425,191 		JBrowse link
G Lipa lipase A, lysosomal acid type affects response to substance ISO LIPA protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G Lrrc47 leucine rich repeat containing 47 decreases expression ISO Etoposide results in decreased expression of LRRC47 mRNA CTD PMID:24211769 NCBI chr 5:164,570,539...164,580,174
Ensembl chr 5:164,570,435...164,580,174 		JBrowse link
G Ltbr lymphotoxin beta receptor multiple interactions
increases expression		 ISO Estradiol inhibits the reaction [Etoposide results in increased expression of LTBR mRNA] CTD PMID:19426747 NCBI chr 4:158,108,884...158,115,339
Ensembl chr 4:158,108,886...158,121,539 		JBrowse link
G Lxn latexin increases response to substance ISO LXN protein results in increased susceptibility to Etoposide CTD PMID:25341047 NCBI chr 2:151,727,556...151,733,426
Ensembl chr 2:151,727,102...151,733,460 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E affects response to substance ISO LY6E protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689 		JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 affects response to substance ISO MACF1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:135,623,734...135,949,097
Ensembl chr 5:135,623,742...135,945,905 		JBrowse link
G Man2b1 mannosidase, alpha, class 2B, member 1 increases expression ISO Etoposide results in increased expression of MAN2B1 mRNA CTD PMID:25270620 NCBI chr19:23,055,092...23,074,398
Ensembl chr19:23,055,097...23,074,389 		JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 increases expression ISO Etoposide results in increased expression of MAP2K3 mRNA CTD PMID:17374387 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 decreases expression ISO Etoposide results in decreased expression of MAP3K5 mRNA CTD PMID:17374387 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Map7 microtubule-associated protein 7 affects response to substance ISO MAP7 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:14,910,433...15,037,574
Ensembl chr 1:14,910,551...15,037,574 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation		 ISO 3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Etoposide results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Etoposide results in increased phosphorylation of MAPK1 protein] CTD PMID:16014620 PMID:19720055 PMID:26046675 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk12 mitogen-activated protein kinase 12 increases activity
affects response to substance
multiple interactions		 ISO Etoposide results in increased activity of MAPK12 protein
MAPK12 protein affects the susceptibility to Etoposide
[MAPK12 protein results in increased phosphorylation of TOP2A protein] which results in increased susceptibility to Etoposide; [MAPK12 protein results in increased stability of TOP2A protein] which results in increased susceptibility to Etoposide		 CTD PMID:21878638 NCBI chr 7:120,206,005...120,216,711
Ensembl chr 7:120,206,271...120,216,664 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation		 ISO 3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Etoposide results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Etoposide results in increased phosphorylation of MAPK3 protein] CTD PMID:16014620 PMID:19720055 PMID:26046675 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 multiple interactions
increases phosphorylation		 ISO (4-(5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl)pyridin-2-yl)-(1-phenylethyl)amine inhibits the reaction [Etoposide results in increased phosphorylation of MAPKAPK2 protein] CTD PMID:17003255 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457 		JBrowse link
G Matn2 matrilin 2 affects response to substance ISO MATN2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:65,494,996...65,644,613
Ensembl chr 7:65,494,834...65,645,113 		JBrowse link
G Mbp myelin basic protein affects response to substance ISO MBP protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mcam melanoma cell adhesion molecule increases expression ISO Etoposide results in increased expression of MCAM mRNA CTD PMID:25270620 NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions
decreases expression		 ISO wortmannin promotes the reaction [Etoposide results in decreased expression of MCL1 protein] CTD PMID:17935137 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor decreases expression ISO Etoposide results in decreased expression of MCM10 mRNA CTD PMID:24211769 NCBI chr17:73,263,788...73,288,346
Ensembl chr17:73,266,095...73,287,364 		JBrowse link
G Mcm2 minichromosome maintenance complex component 2 decreases expression ISO Etoposide results in decreased expression of MCM2 mRNA CTD PMID:16120219 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847 		JBrowse link
G Mcm6 minichromosome maintenance complex component 6 decreases expression ISO Etoposide results in decreased expression of MCM6 mRNA CTD PMID:16120219 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960 		JBrowse link
G Mcm7 minichromosome maintenance complex component 7 decreases expression ISO Etoposide results in decreased expression of MCM7 mRNA CTD PMID:16120219 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063 		JBrowse link
G Mcm8 minichromosome maintenance 8 homologous recombination repair factor decreases expression ISO Etoposide results in decreased expression of MCM8 mRNA CTD PMID:16120219 NCBI chr 3:120,086,741...120,117,008
Ensembl chr 3:120,086,763...120,117,008 		JBrowse link
G Mdfic MyoD family inhibitor domain containing affects response to substance ISO MDFIC protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:43,972,310...44,052,162
Ensembl chr 4:43,972,507...44,052,161 		JBrowse link
G Mdh2 malate dehydrogenase 2 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of MDH2 protein CTD PMID:29733421 NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271 		JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions
decreases expression
increases phosphorylation
increases expression
decreases response to substance		 ISO
EXP		 benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]]; Cadmium Chloride affects the reaction [Etoposide results in increased phosphorylation of MDM2 protein]; Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]; IKBKB protein promotes the reaction [Etoposide results in increased expression of MDM2 protein modified form]; IKBKB protein promotes the reaction [Etoposide results in increased expression of MDM2 protein]; Wortmannin promotes the reaction [Etoposide results in increased phosphorylation of MDM2 protein]
Etoposide results in decreased expression of MDM2 protein
Etoposide results in increased expression of MDM2 mRNA; Etoposide results in increased expression of MDM2 protein; Etoposide results in increased expression of MDM2 protein modified form
Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased expression of MDM2 protein]
MDM2 promoter SNP results in decreased susceptibility to Etoposide		 CTD PMID:15459018 PMID:16120219 PMID:17575151 PMID:17935137 PMID:18096571 More... NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Me2 malic enzyme 2 decreases expression ISO Etoposide results in decreased expression of ME2 protein CTD PMID:29733421 NCBI chr18:67,350,833...67,400,987
Ensembl chr18:67,355,795...67,400,987 		JBrowse link
G Mir135b microRNA 135b increases expression ISO Etoposide results in increased expression of MIR135B mRNA CTD PMID:27570640 NCBI chr13:43,638,857...43,638,953
Ensembl chr13:43,638,857...43,638,953 		JBrowse link
G Mir139 microRNA 139 increases expression ISO Etoposide results in increased expression of MIR139 mRNA CTD PMID:29397400 NCBI chr 1:155,878,828...155,878,895
Ensembl chr 1:155,878,825...155,878,902 		JBrowse link
G Mir196b microRNA 196b increases expression ISO Etoposide results in increased expression of MIR196B mRNA CTD PMID:27570640 NCBI chr 4:81,330,487...81,330,571
Ensembl chr 4:81,330,487...81,330,571 		JBrowse link
G Mir34c microRNA 34c increases expression ISO Etoposide results in increased expression of MIR34C mRNA CTD PMID:29397400 NCBI chr 8:51,409,726...51,409,802
Ensembl chr 8:51,409,726...51,409,802 		JBrowse link
G Mlana melan-A affects response to substance ISO MLANA protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:227,469,537...227,483,343
Ensembl chr 1:227,469,537...227,483,343 		JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor affects response to substance ISO MLLT11 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199 		JBrowse link
G Mmp1 matrix metallopeptidase 1 decreases expression
multiple interactions		 ISO Etoposide results in decreased expression of MMP1 protein
pifithrin inhibits the reaction [Etoposide results in decreased expression of MMP1 protein]		 CTD PMID:18557930 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mocos molybdenum cofactor sulfurase affects response to substance ISO MOCOS protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr18:15,931,659...15,977,415
Ensembl chr18:15,931,654...15,977,187 		JBrowse link
G Mpo myeloperoxidase increases metabolic processing ISO MPO protein results in increased metabolism of Etoposide CTD PMID:16841962 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mpzl1 myelin protein zero-like 1 decreases expression ISO Etoposide results in decreased expression of MPZL1 mRNA CTD PMID:24211769 NCBI chr13:77,852,467...77,889,305
Ensembl chr13:77,852,467...77,896,616 		JBrowse link
G Mr1 major histocompatibility complex, class I-related increases expression
affects expression		 ISO Etoposide results in increased expression of MR1 mRNA
Etoposide affects the expression of MR1 mRNA		 CTD PMID:21527772 PMID:25811541 NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970 		JBrowse link
G Mras muscle RAS oncogene homolog decreases expression ISO Etoposide results in decreased expression of MRAS mRNA CTD PMID:25270620 NCBI chr 8:99,944,036...100,006,771
Ensembl chr 8:99,944,036...99,996,408 		JBrowse link
G Mrc1 mannose receptor, C type 1 decreases expression ISO Etoposide results in decreased expression of MRC1 mRNA CTD PMID:25270620 NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857 		JBrowse link
G Mrm2 mitochondrial rRNA methyltransferase 2 decreases expression ISO Etoposide results in decreased expression of MRM2 mRNA CTD PMID:24211769 NCBI chr12:14,309,556...14,314,759
Ensembl chr12:14,251,941...14,314,118 		JBrowse link
G Msc musculin decreases expression ISO Etoposide results in decreased expression of MSC mRNA CTD PMID:25270620 NCBI chr 5:4,547,335...4,553,206
Ensembl chr 5:4,547,405...4,553,203 		JBrowse link
G Msh6 mutS homolog 6 decreases expression ISO Etoposide results in decreased expression of MSH6 mRNA CTD PMID:24211769 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956 		JBrowse link
G Mt-nd4 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 increases expression ISO Etoposide results in increased expression of ND4 mRNA CTD PMID:26259609 NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
NCBI chr MT:10,160...11,537
Ensembl chr MT:10,160...11,537 		JBrowse link
G Mt2A metallothionein 2A decreases expression
multiple interactions		 ISO Etoposide results in decreased expression of MT2A protein
XAF1 protein affects the reaction [Etoposide results in decreased expression of MT2A protein]		 CTD PMID:28507149 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression ISO Etoposide results in decreased expression of MTHFD2 mRNA CTD PMID:25270620 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608 		JBrowse link
G Mtor mechanistic target of rapamycin kinase increases phosphorylation ISO Etoposide results in increased phosphorylation of MTOR protein CTD PMID:27769712 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Mtus1 microtubule associated scaffold protein 1 affects response to substance ISO MTUS1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:51,202,497...51,347,794
Ensembl chr16:51,253,562...51,347,793 		JBrowse link
G Mxi1 MAX interactor 1, dimerization protein affects response to substance ISO MXI1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
increases response to substance
multiple interactions		 ISO Etoposide results in decreased expression of MYC; Etoposide results in decreased expression of MYC mRNA
MYC protein results in increased susceptibility to Etoposide
MYC protein promotes the reaction [Etoposide results in increased cleavage of CASP9 protein]		 CTD PMID:9454737 PMID:21324178 PMID:21527772 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor multiple interactions
decreases response to substance		 ISO [MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Etoposide
MYCN protein results in decreased susceptibility to Etoposide		 CTD PMID:10348353 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590 		JBrowse link
G Myh7 myosin heavy chain 7 decreases expression ISO Etoposide results in decreased expression of MYH7 mRNA CTD PMID:29397400 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217 		JBrowse link
G Myl2 myosin light chain 2 decreases expression ISO Etoposide results in decreased expression of MYL2 mRNA CTD PMID:29397400 NCBI chr12:34,454,223...34,468,554
Ensembl chr12:34,454,218...34,468,983 		JBrowse link
G Myl3 myosin light chain 3 decreases expression ISO Etoposide results in decreased expression of MYL3 mRNA CTD PMID:29397400 NCBI chr 8:110,738,669...110,744,814
Ensembl chr 8:110,738,661...110,744,816 		JBrowse link
G Myom2 myomesin 2 decreases expression ISO Etoposide results in decreased expression of MYOM2 mRNA CTD PMID:29397400 NCBI chr16:74,520,148...74,592,658
Ensembl chr16:74,520,157...74,592,772 		JBrowse link
G Myot myotilin increases expression ISO Etoposide results in increased expression of MYOT mRNA CTD PMID:29397400 NCBI chr18:36,705,244...36,724,849
Ensembl chr18:36,705,314...36,724,841 		JBrowse link
G Myt1 myelin transcription factor 1 decreases expression ISO Etoposide results in decreased expression of MYT1 mRNA CTD PMID:16120219 NCBI chr 3:168,890,466...168,950,341
Ensembl chr 3:168,886,089...168,950,341 		JBrowse link
G Nabp2 nucleic acid binding protein 2 multiple interactions
increases acetylation		 ISO 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Etoposide results in increased acetylation of NABP2 protein] CTD PMID:26170237 NCBI chr 7:830,949...836,551
Ensembl chr 7:830,949...838,027 		JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 affects response to substance ISO NAP1L1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593 		JBrowse link
G Nck2 NCK adaptor protein 2 decreases expression ISO Etoposide results in decreased expression of NCK2 mRNA CTD PMID:17374387 NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 decreases expression ISO Etoposide results in decreased expression of NECTIN2 mRNA CTD PMID:25270620 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360 		JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 affects response to substance ISO NEDD9 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019 		JBrowse link
G Nek2 NIMA-related kinase 2 decreases expression ISO Etoposide results in decreased expression of NEK2 mRNA CTD PMID:16120219 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases response to substance
multiple interactions		 ISO NFE2L2 mRNA results in decreased susceptibility to Etoposide; NFE2L2 protein results in decreased susceptibility to Etoposide
NFE2L2 protein affects the reaction [Etoposide results in increased expression of SRXN1 protein]; NFE2L2 protein affects the reaction [Etoposide results in increased expression of TP53 protein]; trigonelline inhibits the reaction [NFE2L2 protein results in decreased susceptibility to Etoposide]		 CTD PMID:26708503 PMID:27982581 PMID:33148531 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO NFKB1 protein affects the reaction [Etoposide results in increased expression of TP53 protein]; NFKB1 protein affects the reaction [Etoposide results in increased phosphorylation of AKT1 protein] CTD PMID:23396362 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases degradation		 ISO wortmannin inhibits the reaction [Etoposide results in increased degradation of NFKBIA protein] CTD PMID:12637521 PMID:17935137 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 increases expression ISO Etoposide results in increased expression of NHERF1 mRNA CTD PMID:25270620 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598 		JBrowse link
G Niban1 niban apoptosis regulator 1 affects response to substance ISO NIBAN1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729 		JBrowse link
G Nit2 nitrilase family, member 2 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of NIT2 protein CTD PMID:29733421 NCBI chr11:43,363,839...43,378,713
Ensembl chr11:43,363,985...43,375,024 		JBrowse link
G Nmt2 N-myristoyltransferase 2 affects response to substance ISO NMT2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr17:74,917,833...74,964,788
Ensembl chr17:74,917,833...74,961,080 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression EXP
ISO		 Etoposide results in increased expression of NOS2 mRNA
Etoposide results in increased expression of NOS2 protein		 CTD PMID:15135310 PMID:26259609 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Npas1 neuronal PAS domain protein 1 increases expression ISO Etoposide results in increased expression of NPAS1 mRNA CTD PMID:21527772 NCBI chr 1:77,167,375...77,187,887
Ensembl chr 1:77,167,381...77,186,762 		JBrowse link
G Npnt nephronectin increases expression ISO Etoposide results in increased expression of NPNT mRNA CTD PMID:25270620 NCBI chr 2:221,391,151...221,459,527
Ensembl chr 2:221,391,153...221,459,401 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 affects response to substance
increases expression
multiple interactions		 ISO NQO1 protein affects the susceptibility to Etoposide
Etoposide results in increased expression of NQO1 mRNA
HIPK2 protein promotes the reaction [Etoposide results in increased expression of NQO1 mRNA]		 CTD PMID:16217747 PMID:20980392 PMID:29397400 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 decreases expression ISO Etoposide results in decreased expression of NR0B1 mRNA CTD PMID:25270620 NCBI chr  X:50,756,886...50,761,014
Ensembl chr  X:50,756,886...50,761,011 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 affects localization
affects response to substance
multiple interactions		 ISO Etoposide affects the localization of NR1H2 protein
NR1H2 protein affects the susceptibility to Etoposide
Etoposide promotes the reaction [NR1H2 protein results in increased expression of CETP mRNA]; NR1H2 mutant form inhibits the reaction [Etoposide results in increased expression of CETP mRNA]		 CTD PMID:25914138 NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions
affects response to substance
increases expression		 ISO Etoposide promotes the reaction [NR1H3 protein results in increased expression of CETP mRNA]; Etoposide results in increased expression of and affects the localization of NR1H3 protein; NR1H3 mutant form inhibits the reaction [Etoposide results in increased expression of CETP mRNA]
NR1H3 protein affects the susceptibility to Etoposide
Etoposide results in increased expression of NR1H3 mRNA		 CTD PMID:25914138 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 affects response to substance
multiple interactions
increases activity		 ISO NR1I2 protein affects the susceptibility to Etoposide
[Etoposide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA		 CTD PMID:17279585 PMID:25455453 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO Etoposide inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein] CTD PMID:30818834 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nrap nebulin-related anchoring protein decreases expression ISO Etoposide results in decreased expression of NRAP mRNA CTD PMID:29397400 NCBI chr 1:255,350,113...255,427,704
Ensembl chr 1:255,350,113...255,427,693 		JBrowse link
G Nrg1 neuregulin 1 increases expression ISO Etoposide results in increased expression of NRG1 mRNA CTD PMID:29397400 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Nrip1 nuclear receptor interacting protein 1 affects response to substance
decreases expression		 ISO NRIP1 protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of NRIP1 mRNA; Etoposide results in decreased expression of NRIP1 protein		 CTD PMID:16217747 PMID:25914138 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator affects response to substance
decreases expression		 ISO NUPR1 protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of NUPR1 mRNA		 CTD PMID:16217747 PMID:25270620 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G Oat ornithine aminotransferase multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of OAT protein CTD PMID:29733421 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682 		JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein affects response to substance ISO OCA2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:107,116,278...107,446,093
Ensembl chr 1:107,116,278...107,446,074 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases expression
multiple interactions		 ISO Etoposide results in decreased expression of OGG1 mRNA
wogonin inhibits the reaction [Etoposide results in decreased expression of OGG1 mRNA]		 CTD PMID:23872129 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G P2rx7 purinergic receptor P2X 7 increases expression ISO Etoposide results in increased expression of P2RX7 mRNA CTD PMID:25270620 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 decreases expression ISO Etoposide results in decreased expression of PABPC1 protein CTD PMID:29733421 NCBI chr 7:67,777,438...67,789,731
Ensembl chr 7:67,777,381...67,789,744 		JBrowse link
G Palb2 partner and localizer of BRCA2 decreases expression ISO Etoposide results in decreased expression of PALB2 mRNA CTD PMID:24211769 NCBI chr 1:176,665,076...176,689,053
Ensembl chr 1:176,665,076...176,688,990 		JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 increases expression ISO Etoposide results in increased expression of PAPSS2 mRNA CTD PMID:25270620 NCBI chr 1:230,454,314...230,539,332
Ensembl chr 1:230,454,426...230,539,331 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
increases degradation		 EXP
ISO		 Etoposide results in increased cleavage of PARP1 protein
3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of PARP1 protein]; [Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]; [trigonelline co-treated with Etoposide] results in increased cleavage of PARP1 protein; BCL2 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]; BCL2L1 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]; CD40LG protein inhibits the reaction [Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]; HTATIP2 protein promotes the reaction [Etoposide results in increased activity of PARP1 protein]; Nicotine inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]; PTEN protein modified form promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]; PTEN protein promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]; Wortmannin promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]; XAF1 protein affects the reaction [Etoposide results in increased cleavage of PARP1 protein]
Niacin deficiency affects the reaction [Etoposide results in increased cleavage of PARP1 protein]		 CTD PMID:8840993 PMID:9454737 PMID:12690110 PMID:16014620 PMID:16545138 More... NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pbk PDZ binding kinase affects response to substance ISO PBK protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014 		JBrowse link
G Pcbp2 poly(rC) binding protein 2 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PCBP2 protein CTD PMID:29733421 NCBI chr 7:133,605,375...133,631,312
Ensembl chr 7:133,605,573...133,629,863 		JBrowse link
G Pcbp4 poly(rC) binding protein 4 decreases expression ISO Etoposide results in decreased expression of PCBP4 mRNA CTD PMID:25270620 NCBI chr 8:107,092,688...107,103,276
Ensembl chr 8:107,093,013...107,103,276 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) decreases expression ISO Etoposide results in decreased expression of PCK2 mRNA CTD PMID:25270620 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283 		JBrowse link
G Pde2a phosphodiesterase 2A decreases expression ISO Etoposide results in decreased expression of PDE2A mRNA CTD PMID:25270620 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434 		JBrowse link
G Pde4b phosphodiesterase 4B affects response to substance ISO PDE4B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
G Pdgfc platelet derived growth factor C affects response to substance ISO PDGFC protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:166,316,870...166,493,449
Ensembl chr 2:166,316,803...166,493,433 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of PDIA3 protein CTD PMID:24478030 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 decreases expression ISO Etoposide results in decreased expression of PDK1 mRNA CTD PMID:29397400 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO Etoposide results in increased expression of PDK4 mRNA CTD PMID:29397400 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
G Pdlim3 PDZ and LIM domain 3 increases expression ISO Etoposide results in increased expression of PDLIM3 mRNA CTD PMID:29397400 NCBI chr16:46,352,460...46,383,680
Ensembl chr16:46,352,467...46,383,657 		JBrowse link
G Pelo pelota mRNA surveillance and ribosome rescue factor decreases expression ISO Etoposide results in decreased expression of PELO mRNA CTD PMID:24211769 NCBI chr 2:46,797,853...46,799,621
Ensembl chr 2:46,797,853...46,799,746 		JBrowse link
G Perp p53 apoptosis effector related to PMP22 increases expression ISO Etoposide results in increased expression of PERP mRNA CTD PMID:21382384 PMID:25270620 NCBI chr 1:13,542,067...13,554,514
Ensembl chr 1:13,542,067...13,554,511 		JBrowse link
G Phgdh phosphoglycerate dehydrogenase affects response to substance ISO PHGDH protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944 		JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 increases expression ISO Etoposide results in increased expression of PHLDA3 mRNA CTD PMID:25270620 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335 		JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A multiple interactions ISO [Cisplatin co-treated with Etoposide] results in increased mutagenesis of PIGA CTD PMID:21826740 NCBI chr  X:30,043,033...30,055,861
Ensembl chr  X:30,042,343...30,055,804 		JBrowse link
G Pip5k1b phosphatidylinositol-4-phosphate 5-kinase type 1 beta affects response to substance ISO PIP5K1B protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:221,907,220...222,183,672
Ensembl chr 1:221,914,159...222,183,672 		JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO Etoposide results in increased expression of PLAU mRNA CTD PMID:21527772 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plk1 polo-like kinase 1 decreases expression ISO Etoposide results in decreased expression of PLK1 mRNA CTD PMID:25270620 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400 		JBrowse link
G Plk2 polo-like kinase 2 increases expression ISO Etoposide results in increased expression of PLK2 mRNA CTD PMID:21527772 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947 		JBrowse link
G Plk3 polo-like kinase 3 increases expression ISO Etoposide results in increased expression of PLK3 mRNA CTD PMID:17374387 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317 		JBrowse link
G Plp1 proteolipid protein 1 affects response to substance ISO PLP1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032 		JBrowse link
G Plpp2 phospholipid phosphatase 2 decreases expression ISO Etoposide results in decreased expression of PLPP2 mRNA CTD PMID:25270620 NCBI chr 7:10,175,918...10,184,032
Ensembl chr 7:10,175,948...10,184,071 		JBrowse link
G Pm20d1 peptidase M20 domain containing 1 increases expression ISO Etoposide results in increased expression of PM20D1 mRNA CTD PMID:25270620 NCBI chr13:43,237,954...43,259,999
Ensembl chr13:43,237,971...43,259,999 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Etoposide results in increased expression of PMAIP1 mRNA CTD PMID:21801448 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Pmel premelanosome protein affects response to substance ISO PMEL protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:1,138,202...1,148,735
Ensembl chr 7:1,138,586...1,148,746 		JBrowse link
G Pmp2 peripheral myelin protein 2 affects response to substance ISO PMP2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:91,611,334...91,615,252
Ensembl chr 2:91,611,334...91,615,252 		JBrowse link
G Pmp22 peripheral myelin protein 22 affects response to substance ISO PMP22 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714 		JBrowse link
G Polq DNA polymerase theta decreases response to substance ISO POLQ results in decreased susceptibility to Etoposide CTD PMID:21883722 NCBI chr11:63,673,796...63,775,905
Ensembl chr11:63,673,816...63,775,878 		JBrowse link
G Polr1h RNA polymerase I subunit H decreases response to substance
multiple interactions		 ISO POLR1H protein results in decreased susceptibility to Etoposide
Verapamil inhibits the reaction [POLR1H protein results in decreased susceptibility to Etoposide]		 CTD PMID:14726695 NCBI chr20:1,594,936...1,598,854
Ensembl chr20:1,594,936...1,598,854 		JBrowse link
G Postn periostin increases expression ISO Etoposide results in increased expression of POSTN mRNA CTD PMID:29397400 NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 increases expression ISO Etoposide results in increased expression of POU5F1 mRNA; Etoposide results in increased expression of POU5F1 protein CTD PMID:33969609 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression
multiple interactions		 ISO Etoposide results in increased expression of PPARGC1A mRNA
Etoposide promotes the reaction [PPARGC1A protein results in increased activity of ESRRA protein]		 CTD PMID:26259609 PMID:30818834 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ppargc1b PPARG coactivator 1 beta increases expression ISO Etoposide results in increased expression of PPARGC1B mRNA CTD PMID:26259609 NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194 		JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D increases expression ISO Etoposide results in increased expression of PPM1D protein CTD PMID:25078064 NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607 		JBrowse link
G Ppp1r13l protein phosphatase 1, regulatory subunit 13 like increases expression
multiple interactions
decreases response to substance		 ISO Etoposide results in increased expression of PPP1R13L mRNA
Etoposide results in increased expression of and results in increased localization of PPP1R13L protein
PPP1R13L results in decreased susceptibility to Etoposide		 CTD PMID:17570360 PMID:19299014 NCBI chr 1:79,010,997...79,030,714
Ensembl chr 1:79,011,745...79,030,712 		JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression ISO Etoposide results in decreased expression of PRC1 mRNA CTD PMID:17374387 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765 		JBrowse link
G Prdx1 peroxiredoxin 1 decreases expression ISO Etoposide results in decreased expression of PRDX1 protein CTD PMID:29733421 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1 increases expression ISO Etoposide results in increased expression of PRKAB1 mRNA CTD PMID:24211769 NCBI chr12:40,588,140...40,598,673
Ensembl chr12:40,588,211...40,598,661 		JBrowse link
G Prkcd protein kinase C, delta multiple interactions ISO Etoposide results in increased cleavage of and results in increased activity of PRKCD protein CTD PMID:19662097 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prkcz protein kinase C, zeta increases response to substance ISO PRKCZ protein results in increased susceptibility to Etoposide CTD PMID:21863889 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit increases phosphorylation
multiple interactions		 ISO Etoposide results in increased phosphorylation of PRKDC protein
PRKDC protein promotes the reaction [Etoposide results in increased phosphorylation of SP1 protein]		 CTD PMID:17441964 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Prkx protein kinase cAMP-dependent X-linked catalytic subunit increases expression ISO Etoposide results in increased expression of PRKX mRNA CTD PMID:29397400 NCBI chr  X:41,823,349...41,866,844
Ensembl chr  X:41,823,355...41,866,669 		JBrowse link
G Prnp prion protein decreases response to substance ISO PRNP protein results in decreased susceptibility to Etoposide CTD PMID:15386405 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
G Procr protein C receptor increases expression ISO Etoposide results in increased expression of PROCR mRNA CTD PMID:21527772 NCBI chr 3:144,254,596...144,258,863
Ensembl chr 3:144,254,380...144,258,903 		JBrowse link
G Psmd13 proteasome 26S subunit, non-ATPase 13 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PSMD13 protein CTD PMID:29733421 NCBI chr 1:195,964,617...195,976,895
Ensembl chr 1:195,964,138...195,976,905 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions
increases response to substance		 ISO PTEN protein inhibits the reaction [Etoposide results in increased phosphorylation of and results in increased activity of AKT1 protein]; PTEN protein modified form promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]; PTEN protein promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]; Wortmannin inhibits the reaction [PTEN protein results in increased susceptibility to Etoposide] CTD PMID:16807353 PMID:17935137 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions		 ISO Etoposide results in increased expression of PTGS2 protein
PTGS2 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Etoposide]		 CTD PMID:24184161 PMID:26259609 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pus3 pseudouridine synthase 3 decreases expression ISO Etoposide results in decreased expression of PUS3 mRNA CTD PMID:24211769 NCBI chr 8:33,910,461...33,918,716
Ensembl chr 8:33,911,357...33,918,714 		JBrowse link
G Pygm glycogen phosphorylase, muscle associated decreases expression ISO Etoposide results in decreased expression of PYGM mRNA CTD PMID:29397400 NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368 		JBrowse link
G Rab17 RAB17, member RAS oncogene family affects response to substance ISO RAB17 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 9:91,552,924...91,566,759
Ensembl chr 9:91,553,464...91,566,451 		JBrowse link
G Rab20 RAB20, member RAS oncogene family affects response to substance ISO RAB20 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:78,019,337...78,043,529
Ensembl chr16:78,019,337...78,043,529 		JBrowse link
G Rad51 RAD51 recombinase affects localization EXP Etoposide affects the localization of RAD51 protein CTD PMID:9885240 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
G Rad52 RAD52 homolog, DNA repair protein multiple interactions
increases expression		 ISO BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of RAD52 protein]
Etoposide results in increased expression of RAD52 mRNA; Etoposide results in increased expression of RAD52 protein		 CTD PMID:16417649 PMID:19799994 NCBI chr 4:153,106,062...153,128,598
Ensembl chr 4:153,106,062...153,128,207 		JBrowse link
G Rad54b RAD54 homolog B multiple interactions ISO RAD54B protein affects the reaction [Etoposide results in increased expression of H2AX protein] CTD PMID:33823233 NCBI chr 5:25,032,112...25,104,630
Ensembl chr 5:25,032,066...25,104,616 		JBrowse link
G Rad54l RAD54 like multiple interactions
increases expression		 ISO BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of RAD54L protein] CTD PMID:16417649 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070 		JBrowse link
G Rasip1 Ras interacting protein 1 affects response to substance ISO RASIP1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:96,097,135...96,109,564
Ensembl chr 1:96,091,074...96,109,562 		JBrowse link
G Rassf1 Ras association domain family member 1 multiple interactions
increases response to substance		 ISO [RASSF1 co-treated with Etoposide] affects the folding of and results in increased activity of BAX protein; [RASSF1 co-treated with Etoposide] results in increased cleavage of CASP3 protein; [RASSF1 co-treated with Etoposide] results in increased expression of CDKN1A protein; ABT-737 promotes the reaction [RASSF1 results in increased susceptibility to Etoposide] CTD PMID:21880625 NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164 		JBrowse link
G Rb1 RB transcriptional corepressor 1 affects response to substance
decreases phosphorylation
multiple interactions		 ISO RB1 protein affects the susceptibility to Etoposide
Etoposide results in decreased phosphorylation of RB1 protein
[Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in decreased phosphorylation of RB1 protein]		 CTD PMID:9454737 PMID:17640669 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rbm17 RNA binding motif protein 17 decreases response to substance ISO RBM17 protein results in decreased susceptibility to Etoposide CTD PMID:16061639 NCBI chr17:66,937,140...66,954,034
Ensembl chr17:66,937,140...66,954,014 		JBrowse link
G Rbm34 RNA binding motif protein 34 decreases expression ISO Etoposide results in decreased expression of RBM34 mRNA CTD PMID:24211769 NCBI chr19:54,936,516...54,956,810
Ensembl chr19:54,936,531...54,956,715 		JBrowse link
G Rcan1 regulator of calcineurin 1 affects response to substance ISO RCAN1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of ABCB1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in increased expression of BCL2L1 protein] inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; [[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide; resveratrol inhibits the reaction [[[[Hyaluronic Acid binds to CD44 protein] which results in increased expression of and results in increased activity of EP300 protein] which results in increased acetylation of and results in increased activity of RELA protein] which results in decreased susceptibility to Etoposide] CTD PMID:19047049 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Retsat retinol saturase increases expression ISO Etoposide results in increased expression of RETSAT mRNA CTD PMID:21527772 NCBI chr 4:104,653,306...104,662,069
Ensembl chr 4:104,653,155...104,668,310 		JBrowse link
G Rfc1 replication factor C subunit 1 decreases expression ISO Etoposide results in decreased expression of RFC1 mRNA CTD PMID:24211769 NCBI chr14:42,966,279...43,041,372
Ensembl chr14:42,966,324...43,041,370 		JBrowse link
G Rgcc regulator of cell cycle increases expression ISO Etoposide results in increased expression of RGCC mRNA CTD PMID:29397400 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 multiple interactions
increases expression		 ISO Estradiol inhibits the reaction [Etoposide results in increased expression of RIPK2 mRNA] CTD PMID:19426747 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Ripply3 ripply transcriptional repressor 3 increases expression ISO Etoposide results in increased expression of RIPPLY3 mRNA CTD PMID:21527772 NCBI chr11:33,648,471...33,656,587
Ensembl chr11:33,648,486...33,656,584 		JBrowse link
G Rnf113a1 ring finger protein 113A1 decreases expression ISO Etoposide results in decreased expression of RNF113A mRNA CTD PMID:24211769 NCBI chr  X:116,427,941...116,429,164
Ensembl chr  X:116,427,684...116,433,762 		JBrowse link
G Robo1 roundabout guidance receptor 1 affects response to substance ISO ROBO1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Robo3 roundabout guidance receptor 3 increases expression ISO Etoposide results in increased expression of ROBO3 mRNA CTD PMID:21527772 NCBI chr 8:37,133,542...37,151,674
Ensembl chr 8:37,133,916...37,151,315 		JBrowse link
G Ropn1 rhophilin associated tail protein 1 affects response to substance ISO ROPN1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr11:66,097,854...66,127,148
Ensembl chr11:66,097,856...66,127,148 		JBrowse link
G Rpl6 ribosomal protein L6 decreases response to substance ISO RPL6 protein results in decreased susceptibility to Etoposide CTD PMID:15846068 NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921 		JBrowse link
G Rps27l ribosomal protein S27-like increases expression ISO Etoposide results in increased expression of RPS27L protein CTD PMID:18056458 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418 		JBrowse link
G Rps6 ribosomal protein S6 increases phosphorylation ISO Etoposide results in increased phosphorylation of RPS6 protein CTD PMID:23396362 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602 		JBrowse link
G Rras RAS related increases expression ISO Etoposide results in increased expression of RRAS mRNA CTD PMID:21527772 NCBI chr 1:95,500,582...95,504,362
Ensembl chr 1:95,500,566...95,504,357 		JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO Etoposide results in increased expression of RRM2B mRNA CTD PMID:21704725 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 affects expression ISO Etoposide affects the expression of HLA-E mRNA CTD PMID:25811541 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-CE16 RT1 class I, locus CE16 affects expression ISO Etoposide affects the expression of HLA-A mRNA CTD PMID:25811541 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
G Rtkn rhotekin increases expression ISO Etoposide results in increased expression of RTKN mRNA CTD PMID:25270620 NCBI chr 4:115,640,813...115,657,952
Ensembl chr 4:115,640,774...115,657,952 		JBrowse link
G Runx1 RUNX family transcription factor 1 increases mutagenesis
increases response to substance		 ISO Etoposide results in increased mutagenesis of RUNX1 gene
RUNX1 gene mutant form results in increased susceptibility to Etoposide		 CTD PMID:15217836 PMID:28624474 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G Runx3 RUNX family transcription factor 3 increases response to substance ISO RUNX3 protein results in increased susceptibility to Etoposide CTD PMID:15756676 NCBI chr 5:147,360,587...147,419,161
Ensembl chr 5:147,360,994...147,419,156 		JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO Etoposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]; Tretinoin promotes the reaction [Etoposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]] CTD PMID:25914138 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Ryr2 ryanodine receptor 2 decreases expression ISO Etoposide results in decreased expression of RYR2 mRNA CTD PMID:29397400 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142 		JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 increases expression ISO Etoposide results in increased expression of SCN3B mRNA CTD PMID:25270620 NCBI chr 8:40,630,372...40,652,869
Ensembl chr 8:40,630,455...40,652,868 		JBrowse link
G Scn4b sodium voltage-gated channel beta subunit 4 increases expression ISO Etoposide results in increased expression of SCN4B mRNA CTD PMID:29397400 NCBI chr 8:45,446,580...45,462,294
Ensembl chr 8:45,446,215...45,462,292 		JBrowse link
G Sdc1 syndecan 1 increases expression ISO Etoposide results in increased expression of SDC1 mRNA CTD PMID:17374387 NCBI chr 6:31,562,799...31,585,267
Ensembl chr 6:31,562,739...31,585,264 		JBrowse link
G Sdhaf1 succinate dehydrogenase complex assembly factor 1 decreases expression ISO Etoposide results in decreased expression of SDHAF1 mRNA CTD PMID:24211769 NCBI chr 1:85,576,207...85,577,156
Ensembl chr 1:85,576,041...85,577,366
Ensembl chr 1:85,576,041...85,577,366 		JBrowse link
G Serpine2 serpin family E member 2 increases expression ISO Etoposide results in increased expression of SERPINE2 mRNA CTD PMID:25270620 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Sesn1 sestrin 1 increases expression ISO Etoposide results in increased expression of SESN1 mRNA CTD PMID:24211769 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697 		JBrowse link
G Sfn stratifin increases expression ISO Etoposide results in increased expression of SFN mRNA CTD PMID:21527772 NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314 		JBrowse link
G Slbp stem-loop histone mRNA binding protein decreases expression ISO Etoposide results in decreased expression of SLBP mRNA CTD PMID:24211769 NCBI chr14:77,071,441...77,081,911
Ensembl chr14:77,071,632...77,081,906 		JBrowse link
G Slc16a6 solute carrier family 16, member 6 affects response to substance ISO SLC16A6 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:94,424,377...94,447,482
Ensembl chr10:94,426,244...94,448,779 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 decreases expression ISO Etoposide results in decreased expression of SLC1A5 mRNA CTD PMID:24211769 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952 		JBrowse link
G Slc22a18 solute carrier family 22, member 18 affects response to substance ISO SLC22A18 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:198,670,626...198,694,977
Ensembl chr 1:198,671,731...198,694,975 		JBrowse link
G Slc27a3 solute carrier family 27 member 3 affects response to substance ISO SLC27A3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:175,853,241...175,857,909
Ensembl chr 2:175,853,241...175,857,909 		JBrowse link
G Slc2a6 solute carrier family 2 member 6 increases expression ISO Etoposide results in increased expression of SLC2A6 mRNA CTD PMID:21527772 NCBI chr 3:10,348,395...10,355,208
Ensembl chr 3:10,348,395...10,355,208 		JBrowse link
G Slc35f2 solute carrier family 35, member F2 decreases expression ISO Etoposide results in decreased expression of SLC35F2 mRNA CTD PMID:25270620 NCBI chr 8:54,159,970...54,203,614
Ensembl chr 8:54,159,970...54,203,612 		JBrowse link
G Slc45a3 solute carrier family 45, member 3 multiple interactions ISO Etoposide inhibits the reaction [Dihydrotestosterone results in increased expression of SLC45A3 mRNA] CTD PMID:20601956 NCBI chr13:43,407,293...43,427,588
Ensembl chr13:43,407,293...43,427,588 		JBrowse link
G Slc4a11 solute carrier family 4 member 11 increases expression ISO Etoposide results in increased expression of SLC4A11 mRNA CTD PMID:25270620 NCBI chr 3:117,900,223...117,912,787
Ensembl chr 3:117,900,223...117,912,674 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 affects response to substance ISO SLC7A11 protein affects the susceptibility to Etoposide CTD PMID:31226288 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Slc7a3 solute carrier family 7 member 3 decreases expression ISO Etoposide results in decreased expression of SLC7A3 mRNA CTD PMID:25270620 NCBI chr  X:66,210,071...66,216,482
Ensembl chr  X:66,210,081...66,215,708 		JBrowse link
G Slc7a5 solute carrier family 7 member 5 affects response to substance ISO SLC7A5 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 decreases expression ISO Etoposide results in decreased expression of SLC8A1 mRNA CTD PMID:29397400 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions ISO Etoposide inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue] CTD PMID:30863990 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
G Smad2 SMAD family member 2 multiple interactions
increases phosphorylation		 ISO 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Etoposide results in increased phosphorylation of SMAD2 protein] CTD PMID:22363485 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smpdl3a sphingomyelin phosphodiesterase, acid-like 3A affects response to substance ISO SMPDL3A protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr20:37,132,592...37,155,567
Ensembl chr20:37,132,592...37,155,567 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression
decreases response to substance		 ISO Etoposide results in increased expression of SOD2 protein
SOD2 protein results in decreased susceptibility to Etoposide		 CTD PMID:10759716 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sohlh1 spermatogenesis and oogenesis specific basic helix-loop-helix 1 decreases expression ISO Etoposide results in decreased expression of SOHLH1 mRNA CTD PMID:29733421 NCBI chr 3:8,662,995...8,667,521
Ensembl chr 3:8,663,318...8,667,388 		JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 affects response to substance ISO SORBS1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:239,107,882...239,330,276
Ensembl chr 1:239,108,777...239,330,169 		JBrowse link
G Sorbs2 sorbin and SH3 domain containing 2 affects response to substance ISO SORBS2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:46,435,220...46,748,743
Ensembl chr16:46,435,237...46,626,514 		JBrowse link
G Sort1 sortilin 1 affects response to substance ISO SORT1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354 		JBrowse link
G Sox10 SRY-box transcription factor 10 affects response to substance ISO SOX10 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 7:110,725,274...110,734,651
Ensembl chr 7:110,725,274...110,735,544 		JBrowse link
G Sox2 SRY-box transcription factor 2 multiple interactions ISO FTL protein affects the reaction [Etoposide results in increased expression of SOX2 protein] CTD PMID:33969609 NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Sp1 Sp1 transcription factor increases phosphorylation
increases expression
increases activity
multiple interactions		 ISO
EXP		 Etoposide results in increased phosphorylation of SP1 protein
Etoposide results in increased expression of SP1 mRNA
Etoposide results in increased activity of SP1 protein
cordycepin inhibits the reaction [Etoposide results in increased activity of SP1 protein]; cordycepin inhibits the reaction [Etoposide results in increased expression of SP1 mRNA]
PRKDC protein promotes the reaction [Etoposide results in increased phosphorylation of SP1 protein]; wortmannin inhibits the reaction [Etoposide results in increased phosphorylation of SP1 protein]		 CTD PMID:17441964 PMID:23690541 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961 		JBrowse link
G Spata18 spermatogenesis associated 18 increases expression ISO Etoposide results in increased expression of SPATA18 mRNA CTD PMID:21527772 PMID:29397400 NCBI chr14:34,531,931...34,558,671
Ensembl chr14:34,531,061...34,558,687 		JBrowse link
G Spp1 secreted phosphoprotein 1 affects response to substance
decreases expression		 ISO SPP1 protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of SPP1 mRNA		 CTD PMID:16217747 PMID:25270620 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Sptssa serine palmitoyltransferase, small subunit A affects response to substance ISO SPTSSA protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:72,144,714...72,156,130
Ensembl chr 6:72,144,714...72,156,214 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression
multiple interactions		 ISO Etoposide results in increased expression of SRXN1 mRNA; Etoposide results in increased expression of SRXN1 protein
NFE2L2 protein affects the reaction [Etoposide results in increased expression of SRXN1 protein]; TP53 protein affects the reaction [Etoposide results in increased expression of SRXN1 protein]		 CTD PMID:22003191 PMID:27358234 PMID:27982581 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448 		JBrowse link
G St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 decreases response to substance ISO ST3GAL5 protein results in decreased susceptibility to Etoposide CTD PMID:16571667 NCBI chr 4:104,134,613...104,192,558
Ensembl chr 4:104,134,613...104,192,558 		JBrowse link
G St6galnac2 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 affects response to substance ISO ST6GALNAC2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:101,910,220...101,928,412
Ensembl chr10:101,909,971...101,915,008
Ensembl chr10:101,909,971...101,915,008 		JBrowse link
G ST7 suppression of tumorigenicity 7 affects response to substance ISO ST7 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:46,041,655...46,289,745
Ensembl chr 4:46,042,236...46,289,740 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO [STAT1 protein results in increased activity of CASP3 protein] which results in increased susceptibility to Etoposide; [STAT1 protein results in increased activity of CASP7 protein] which results in increased susceptibility to Etoposide CTD PMID:18649362 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stc1 stanniocalcin 1 increases expression ISO Etoposide results in increased expression of STC1 mRNA CTD PMID:29397400 NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264 		JBrowse link
G Stip1 stress-induced phosphoprotein 1 increases expression ISO Etoposide results in increased expression of STIP1 protein CTD PMID:29733421 NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476 		JBrowse link
G Stmn1 stathmin 1 affects response to substance ISO STMN1 affects the susceptibility to Etoposide CTD PMID:17172428 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154 		JBrowse link
G Stmn2 stathmin 2 decreases expression ISO Etoposide results in decreased expression of STMN2 mRNA CTD PMID:25270620 NCBI chr 2:93,204,690...93,252,011
Ensembl chr 2:93,204,692...93,252,011 		JBrowse link
G Stom stomatin increases expression ISO Etoposide results in increased expression of STOM mRNA CTD PMID:21527772 NCBI chr 3:18,645,058...18,667,343
Ensembl chr 3:18,644,378...18,667,354 		JBrowse link
G Sytl1 synaptotagmin-like 1 increases expression ISO Etoposide results in increased expression of SYTL1 mRNA CTD PMID:25270620 NCBI chr 5:145,452,524...145,462,940
Ensembl chr 5:145,422,669...145,462,940 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member increases expression ISO Etoposide results in increased expression of TAP1 mRNA CTD PMID:17374387 PMID:21527772 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901 		JBrowse link
G Tax1bp3 Tax1 binding protein 3 increases expression ISO Etoposide results in increased expression of TAX1BP3 mRNA CTD PMID:17374387 NCBI chr10:57,795,845...57,800,363
Ensembl chr10:57,795,382...57,800,363 		JBrowse link
G Tbc1d8 TBC1 domain family, member 8 increases expression ISO Etoposide results in increased expression of TBC1D8 mRNA CTD PMID:25270620 NCBI chr 9:41,651,394...41,761,432
Ensembl chr 9:41,651,395...41,761,409 		JBrowse link
G Tbl1x transducin (beta)-like 1 X-linked decreases expression ISO Etoposide results in decreased expression of TBL1X mRNA CTD PMID:25270620 NCBI chr  X:41,574,558...41,731,117
Ensembl chr  X:41,576,047...41,731,101 		JBrowse link
G Tbpl1 TATA-box binding protein like 1 affects localization ISO Etoposide affects the localization of TBPL1 protein CTD PMID:17085973 NCBI chr 1:22,777,892...22,803,305
Ensembl chr 1:22,778,459...22,803,122
Ensembl chr 1:22,778,459...22,803,122 		JBrowse link
G Tcap titin-cap decreases expression ISO Etoposide results in decreased expression of TCAP mRNA CTD PMID:29397400 NCBI chr10:83,381,719...83,382,887
Ensembl chr10:83,381,719...83,382,887 		JBrowse link
G Tcfl5 transcription factor like 5 affects response to substance ISO TCFL5 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:167,734,471...167,754,174
Ensembl chr 3:167,734,473...167,754,282 		JBrowse link
G Tcp1 t-complex 1 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of TCP1 protein CTD PMID:29733421 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839 		JBrowse link
G Tdrd3 tudor domain containing 3 affects response to substance ISO TDRD3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:63,340,531...63,497,208
Ensembl chr15:63,341,235...63,476,110 		JBrowse link
G Tent5a terminal nucleotidyltransferase 5A affects response to substance ISO TENT5A protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 8:86,222,294...86,229,045
Ensembl chr 8:86,225,357...86,229,045 		JBrowse link
G Tex264 testis expressed 264 decreases expression ISO Etoposide results in decreased expression of TEX264 mRNA CTD PMID:25270620 NCBI chr 8:107,295,806...107,322,858
Ensembl chr 8:107,295,806...107,323,232 		JBrowse link
G Tfam transcription factor A, mitochondrial increases expression ISO Etoposide results in increased expression of TFAM mRNA CTD PMID:26259609 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292 		JBrowse link
G Tfap2a transcription factor AP-2 alpha affects response to substance
increases response to substance		 ISO TFAP2A protein affects the susceptibility to Etoposide
TFAP2A protein results in increased susceptibility to Etoposide		 CTD PMID:16204029 PMID:16217747 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
G Tfec transcription factor EC decreases expression ISO Etoposide results in decreased expression of TFEC mRNA CTD PMID:24211769 NCBI chr 4:45,106,129...45,180,236
Ensembl chr 4:45,107,641...45,180,236 		JBrowse link
G Tff3 trefoil factor 3 affects response to substance ISO TFF3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054 		JBrowse link
G Tfpi tissue factor pathway inhibitor affects response to substance ISO TFPI protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880 		JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 affects response to substance ISO TFPI2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600 		JBrowse link
G Tfrc transferrin receptor multiple interactions
decreases expression		 ISO 1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)pyridin-2-yl)piperazine inhibits the reaction [Etoposide results in decreased expression of TFRC protein]
Etoposide results in decreased expression of TFRC mRNA; Etoposide results in decreased expression of TFRC protein		 CTD PMID:33969609 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tgds TDP-glucose 4,6-dehydratase affects response to substance ISO TGDS protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr15:95,175,064...95,195,555
Ensembl chr15:95,174,608...95,195,554 		JBrowse link
G Tgfa transforming growth factor alpha increases expression ISO Etoposide results in increased expression of TGFA mRNA CTD PMID:15228094 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894 		JBrowse link
G Tgif2 TGFB-induced factor homeobox 2 decreases expression ISO Etoposide results in decreased expression of TGIF2 mRNA CTD PMID:25270620 NCBI chr 3:145,333,152...145,348,599
Ensembl chr 3:145,333,418...145,348,596 		JBrowse link
G Thbs4 thrombospondin 4 increases expression ISO Etoposide results in increased expression of THBS4 mRNA CTD PMID:29397400 NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313 		JBrowse link
G Tipin timeless interacting protein decreases expression ISO Etoposide results in decreased expression of TIPIN mRNA CTD PMID:24211769 NCBI chr 8:64,780,813...64,801,358
Ensembl chr 8:64,780,828...64,801,352 		JBrowse link
G Tm7sf3 transmembrane 7 superfamily member 3 increases expression ISO Etoposide results in increased expression of TM7SF3 mRNA CTD PMID:25270620 NCBI chr 4:179,518,127...179,550,154
Ensembl chr 4:179,518,130...179,550,154 		JBrowse link
G Tmbim4 transmembrane BAX inhibitor motif containing 4 increases expression ISO Etoposide results in increased expression of TMBIM4 mRNA CTD PMID:25270620 NCBI chr 7:55,718,690...55,733,277
Ensembl chr 7:55,718,699...55,742,773 		JBrowse link
G Tmc6 transmembrane channel like 6 affects response to substance ISO TMC6 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:102,982,059...102,999,509
Ensembl chr10:102,971,229...102,998,960 		JBrowse link
G Tmem185b transmembrane protein 185B decreases expression ISO Etoposide results in decreased expression of TMEM185B mRNA CTD PMID:24211769 NCBI chr13:30,647,533...30,650,864
Ensembl chr13:30,647,482...30,650,858 		JBrowse link
G Tmem204 transmembrane protein 204 decreases expression ISO Etoposide results in decreased expression of TMEM204 mRNA CTD PMID:25270620 NCBI chr10:14,076,518...14,104,849
Ensembl chr10:14,076,519...14,101,920 		JBrowse link
G Tmem47 transmembrane protein 47 affects response to substance ISO TMEM47 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr  X:45,421,405...45,447,900
Ensembl chr  X:45,421,405...45,447,900 		JBrowse link
G Tmem97 transmembrane protein 97 affects response to substance ISO TMEM97 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730 		JBrowse link
G Tmsb4x thymosin beta 4, X-linked decreases response to substance
multiple interactions		 ISO TMSB4X protein results in decreased susceptibility to Etoposide
TMSB4X protein inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TMSB4X protein inhibits the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]		 CTD PMID:16364925 NCBI chr  X:27,144,666...27,146,667
Ensembl chr  X:27,128,610...27,146,667 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO
EXP		 Etoposide results in increased expression of TNF mRNA CTD PMID:15135310 PMID:18523641 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B increases expression ISO Etoposide results in increased expression of TNFRSF11B mRNA CTD PMID:11459812 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A multiple interactions
increases expression		 ISO Estradiol inhibits the reaction [Etoposide results in increased expression of TNFRSF12A mRNA] CTD PMID:19426747 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 increases expression ISO Etoposide results in increased expression of TNFRSF14 mRNA CTD PMID:21527772 NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A affects response to substance ISO TNFRSF1A protein affects the susceptibility to Etoposide CTD PMID:20159942 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression ISO Etoposide results in decreased expression of TNFSF11 mRNA CTD PMID:11459812 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tnfsf9 TNF superfamily member 9 increases expression ISO Etoposide results in increased expression of TNFSF9 mRNA CTD PMID:17374387 NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345 		JBrowse link
G Tnks tankyrase affects response to substance ISO TNKS protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr16:57,223,174...57,370,740
Ensembl chr16:57,225,094...57,366,260 		JBrowse link
G Top2a DNA topoisomerase II alpha affects binding
decreases activity
multiple interactions
affects activity
decreases expression
increases response to substance
affects response to substance
decreases response to substance		 ISO Etoposide binds to TOP2A protein
Etoposide analog results in decreased activity of TOP2A protein; Etoposide metabolite results in decreased activity of TOP2A protein; Etoposide results in decreased activity of TOP2A protein
[Ciprofloxacin binds to TOP2A protein] inhibits the reaction [Etoposide binds to TOP2A protein]; [EGF protein results in decreased expression of TOP2A protein] which results in decreased susceptibility to Etoposide; [MAPK12 protein results in increased phosphorylation of TOP2A protein] which results in increased susceptibility to Etoposide; [MAPK12 protein results in increased stability of TOP2A protein] which results in increased susceptibility to Etoposide; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]]; delphinidin results in decreased susceptibility to [Etoposide affects the activity of TOP2A protein]; Etoposide metabolite inhibits the reaction [TOP2A protein binds to Nucleic Acids, Nucleotides, and Nucleosides]; Etoposide metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]; Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]; TOP2A results in decreased susceptibility to [Carboplatin co-treated with Etoposide co-treated with Ifosfamide]; TOP2A results in decreased susceptibility to [Cisplatin co-treated with Etoposide]
Etoposide results in decreased expression of TOP2A protein
TOP2A protein results in increased susceptibility to Etoposide
TOP2A protein modified form affects the susceptibility to Etoposide
TOP2A gene mutant form results in decreased susceptibility to Etoposide; TOP2A protein mutant form results in decreased susceptibility to Etoposide		 CTD PMID:10856430 PMID:11325482 PMID:11470519 PMID:11531262 PMID:11676865 More... NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Top2b DNA topoisomerase II beta decreases response to substance
decreases activity
affects response to substance
decreases expression
multiple interactions
increases response to substance		 ISO TOP2B protein mutant form results in decreased susceptibility to Etoposide
Etoposide results in decreased activity of TOP2B protein
TOP2B protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of TOP2B protein
TOP2B protein affects the reaction [Etoposide results in increased expression of H2AX protein]
TOP2B protein mutant form results in increased susceptibility to Etoposide		 CTD PMID:10856430 PMID:15322234 PMID:16239602 PMID:17875725 PMID:26198043 More... NCBI chr15:9,051,340...9,111,721
Ensembl chr15:9,051,341...9,112,085 		JBrowse link
G Top3a DNA topoisomerase III alpha decreases expression ISO Etoposide results in decreased expression of TOP3A mRNA CTD PMID:24211769 NCBI chr10:45,419,219...45,457,356
Ensembl chr10:45,419,217...45,457,559 		JBrowse link
G Tor1a torsin family 1, member A decreases expression ISO Etoposide results in decreased expression of TOR1A mRNA CTD PMID:24211769 NCBI chr 3:14,250,667...14,257,704
Ensembl chr 3:14,250,676...14,257,691 		JBrowse link
G Tp53 tumor protein p53 increases acetylation
affects activity
increases expression
multiple interactions
increases activity
increases phosphorylation
affects response to substance
increases response to substance		 ISO
EXP		 Etoposide results in increased acetylation of TP53 protein; Etoposide results in increased acetylation of TP53 protein mutant form
Etoposide affects the activity of TP53 protein; Etoposide metabolite affects the activity of TP53 protein
Etoposide results in increased expression of TRP53 protein
[CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the reaction [Etoposide results in increased expression of TRP53 protein]; Etoposide results in increased phosphorylation of and results in increased activity of TRP53 protein; TRP53 affects the reaction [Etoposide results in increased expression of CDKN1A mRNA]; TRP53 affects the reaction [Etoposide results in increased expression of TPT1 mRNA]; TRP53 affects the reaction [Etoposide results in increased expression of TPT1 protein]; TRP53 protein affects the reaction [Etoposide results in increased expression of BTG2 mRNA]
Etoposide results in increased activity of TP53 protein
Etoposide results in increased phosphorylation of TP53 protein
TRP53 protein affects the susceptibility to Etoposide
Etoposide results in increased expression of TP53 protein
[Etoposide results in increased expression of TP53 protein] which results in increased expression of GDF15 protein; Etoposide results in increased expression of TP53 protein
2,4,4'-trichlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]; 2,4,5,2',5'-pentachlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]; 3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Etoposide results in increased expression of TP53 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP9 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of CASP3 protein]; [CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of PARP1 protein]; [CASP8 co-treated with TP53] inhibits the reaction [CASP8 protein mutant form results in decreased susceptibility to Etoposide]; [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of TP53 protein; [Etoposide results in increased acetylation of TP53 protein mutant form] which results in increased expression of UBE2C protein; [TP53 protein results in increased susceptibility to Etoposide] which results in decreased chemical synthesis of benzo(a)pyrene 7,8-dihydrodiol; Cadmium Chloride affects the reaction [Etoposide results in increased phosphorylation of TP53 protein]; DAPK1 protein promotes the reaction [Etoposide results in increased expression of TP53 protein modified form]; DAPK1 protein promotes the reaction [Etoposide results in increased expression of TP53 protein]; entinostat promotes the reaction [Etoposide results in increased expression of and results in increased acetylation of TP53 protein]; Etoposide promotes the reaction [[TP53 protein binds to GDF15 promoter] which results in increased expression of GDF15 mRNA]; Etoposide promotes the reaction [entinostat results in increased expression of TP53 protein]; Etoposide promotes the reaction [TP53 protein binds to TNFRSF10B promoter]; Etoposide promotes the reaction [TP53 protein results in increased chemical synthesis of benzo(a)pyrene 7,8-dihydrodiol]; Etoposide promotes the reaction [trichostatin A results in increased expression of TP53 protein]; Etoposide promotes the reaction [UF010 compound results in increased expression of TP53 protein]; Etoposide results in increased expression of and results in increased acetylation of TP53 protein; Etoposide results in increased phosphorylation of and affects the localization of TP53 protein; Etoposide results in increased phosphorylation of and results in increased activity of TP53 protein; NFE2L2 protein affects the reaction [Etoposide results in increased expression of TP53 protein]; NFKB1 protein affects the reaction [Etoposide results in increased expression of TP53 protein]; Oxygen deficiency inhibits the reaction [Etoposide results in increased phosphorylation of TP53 protein]; pifithrin inhibits the reaction [Etoposide results in increased activity of TP53 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased acetylation of TP53 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased phosphorylation of and results in increased activity of TP53 protein]; TP53 affects the reaction [Etoposide results in increased expression of CDKN1A mRNA]; TP53 affects the reaction [Etoposide results in increased expression of TPT1 mRNA]; TP53 promotes the reaction [Etoposide results in increased expression of BTG2 protein]; TP53 promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; TP53 protein affects the reaction [CHEK1 protein affects the susceptibility to Etoposide]; TP53 protein affects the reaction [Etoposide results in decreased expression of UBE2C mRNA]; TP53 protein affects the reaction [Etoposide results in increased expression of SRXN1 protein]; TP53 protein inhibits the reaction [ESR2 protein results in increased susceptibility to Etoposide]; TP53 protein inhibits the reaction [Etoposide results in decreased expression of UBE2C protein]; TP53 protein modified form inhibits the reaction [Etoposide results in increased expression of BBC3 protein]; TP53 protein promotes the reaction [[Etoposide results in increased susceptibility to Benzo(a)pyrene] which results in increased expression of CDKN1A protein]; TP53 protein promotes the reaction [Etoposide promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]]; TP53 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein]; TP53 protein promotes the reaction [Etoposide results in increased expression of CDKN1A protein]; TP53 protein promotes the reaction [Etoposide results in increased expression of CYP1A1 protein]; TP53 protein promotes the reaction [Etoposide results in increased expression of ETS1 protein]; trichostatin A promotes the reaction [Etoposide results in increased expression of and results in increased acetylation of TP53 protein]; UF010 compound promotes the reaction [Etoposide results in increased expression of and results in increased acetylation of TP53 protein]
cordycepin promotes the reaction [Etoposide results in increased expression of TP53 protein]; Etoposide promotes the reaction [Acetaminophen results in increased phosphorylation of TP53 protein]; Etoposide results in increased expression of and results in increased phosphorylation of TP53 protein; Niacin deficiency inhibits the reaction [Etoposide results in increased expression of TP53 protein]; Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased expression of and results in increased phosphorylation of TP53 protein]
TP53 protein results in increased susceptibility to Etoposide; TP53 results in increased susceptibility to Etoposide		 CTD PMID:9815696 PMID:11895857 PMID:12082016 PMID:15131059 PMID:15459018 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 increases expression
multiple interactions		 ISO Etoposide results in increased expression of TP53BP1 protein
pifithrin inhibits the reaction [Etoposide results in increased expression of and affects the localization of TP53BP1 protein]		 CTD PMID:26259609 PMID:27358234 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822 		JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 increases expression ISO Etoposide results in increased expression of TP53I3 mRNA CTD PMID:17374387 NCBI chr 6:27,818,327...27,825,753 JBrowse link
G Tp73 tumor protein p73 multiple interactions
increases expression		 ISO [[Etoposide results in increased expression of TP73 protein] which results in increased expression of VDR protein] which results in increased susceptibility to Calcitriol; TP73 mutant form inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased activity of CASP7 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; TP73 mutant form inhibits the reaction [Etoposide results in increased cleavage of CASP8 protein]; TP73 protein affects the reaction [Etoposide results in increased expression of VDR mRNA]
Etoposide results in increased expression of TP73 mRNA; Etoposide results in increased expression of TP73 protein		 CTD PMID:17716971 PMID:21801448 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
G Tpi1 triosephosphate isomerase 1 multiple interactions
increases phosphorylation		 ISO CDK2 affects the reaction [Etoposide results in increased phosphorylation of TPI1 protein] CTD PMID:20149834 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541 		JBrowse link
G Tpp2 tripeptidyl peptidase 2 multiple interactions
affects localization		 ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Etoposide affects the localization of TPP2 protein]; SB 203580 inhibits the reaction [Etoposide affects the localization of TPP2 protein]; U 0126 inhibits the reaction [Etoposide affects the localization of TPP2 protein]
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Etoposide affects the localization of TPP2 protein]; Sirolimus promotes the reaction [Etoposide affects the localization of TPP2 protein]; U 0126 inhibits the reaction [Etoposide affects the localization of TPP2 protein]; wortmannin promotes the reaction [Etoposide affects the localization of TPP2 protein]		 CTD PMID:20643100 NCBI chr 9:46,046,712...46,128,157
Ensembl chr 9:46,046,632...46,128,157 		JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 increases expression
multiple interactions		 ISO Etoposide results in increased expression of TPT1 mRNA
TRP53 affects the reaction [Etoposide results in increased expression of TPT1 mRNA]; TRP53 affects the reaction [Etoposide results in increased expression of TPT1 protein]
Etoposide results in increased expression of TPT1 mRNA; Etoposide results in increased expression of TPT1 protein
TP53 affects the reaction [Etoposide results in increased expression of TPT1 mRNA]		 CTD PMID:24067374 NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 affects response to substance ISO TRAF2 protein affects the susceptibility to Etoposide CTD PMID:20159942 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Trib2 tribbles pseudokinase 2 affects response to substance ISO TRIB2 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 6:38,545,971...38,570,349
Ensembl chr 6:38,545,975...38,569,370 		JBrowse link
G Trib3 tribbles pseudokinase 3 decreases expression ISO Etoposide results in decreased expression of TRIB3 mRNA CTD PMID:25270620 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Trim2 tripartite motif-containing 2 affects response to substance
decreases expression		 ISO TRIM2 protein affects the susceptibility to Etoposide
Etoposide results in decreased expression of TRIM2 mRNA		 CTD PMID:16217747 PMID:25270620 NCBI chr 2:169,500,628...169,652,855
Ensembl chr 2:169,500,634...169,652,927 		JBrowse link
G Trim38 tripartite motif containing 38 decreases expression ISO Etoposide results in decreased expression of TRIM38 mRNA CTD PMID:24211769 NCBI chr17:41,351,857...41,365,021 JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 increases expression ISO Etoposide results in increased expression of TRPV1 mRNA CTD PMID:29397400 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Ttk Ttk protein kinase decreases expression ISO Etoposide results in decreased expression of TTK mRNA CTD PMID:16120219 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651 		JBrowse link
G Tuba4a tubulin, alpha 4A increases expression ISO Etoposide results in increased expression of TUBA4A mRNA CTD PMID:21527772 NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918 		JBrowse link
G Tufm Tu translation elongation factor, mitochondrial decreases expression ISO Etoposide results in decreased expression of TUFM protein CTD PMID:29733421 NCBI chr 1:181,073,788...181,077,395
Ensembl chr 1:181,073,788...181,077,395 		JBrowse link
G Txn2 thioredoxin 2 decreases response to substance ISO TXN2 protein results in decreased susceptibility to Etoposide CTD PMID:12080052 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359 		JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO Etoposide results in increased expression of TXNIP protein CTD PMID:18270325 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886 		JBrowse link
G Txnl1 thioredoxin-like 1 decreases expression ISO Etoposide results in decreased expression of TXNL1 protein CTD PMID:29733421 NCBI chr18:57,125,362...57,155,167
Ensembl chr18:57,125,369...57,165,266 		JBrowse link
G Tyms thymidylate synthetase affects response to substance ISO TYMS gene polymorphism affects the susceptibility to Etoposide CTD PMID:15713801 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G Tyrp1 tyrosinase-related protein 1 affects response to substance ISO TYRP1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516 		JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C decreases expression
multiple interactions		 ISO Etoposide results in decreased expression of UBE2C mRNA; Etoposide results in decreased expression of UBE2C protein
[Etoposide results in increased acetylation of TP53 protein mutant form] which results in increased expression of UBE2C protein; CDKN1A protein affects the reaction [Etoposide results in decreased expression of UBE2C protein]; TP53 protein affects the reaction [Etoposide results in decreased expression of UBE2C mRNA]; TP53 protein inhibits the reaction [Etoposide results in decreased expression of UBE2C protein]		 CTD PMID:17374387 PMID:27129209 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339 		JBrowse link
G Ubl3 ubiquitin-like 3 affects response to substance ISO UBL3 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr12:6,473,684...6,518,331
Ensembl chr12:6,473,460...6,518,862 		JBrowse link
G Ucp2 uncoupling protein 2 decreases expression ISO Etoposide results in decreased expression of UCP2 mRNA CTD PMID:29397400 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 affects response to substance
increases glucuronidation		 ISO UGT1A1 gene polymorphism affects the susceptibility to Etoposide
UGT1A1 protein results in increased glucuronidation of Etoposide		 CTD PMID:12969965 PMID:17151191 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of Etoposide CTD PMID:17151191 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Unc5c unc-5 netrin receptor C increases response to substance ISO UNC5C results in increased susceptibility to Etoposide CTD PMID:21600761 NCBI chr 2:230,180,353...230,535,219
Ensembl chr 2:230,180,951...230,535,217 		JBrowse link
G Upp2 uridine phosphorylase 2 increases expression ISO Etoposide results in increased expression of UPP2 mRNA CTD PMID:25270620 NCBI chr 3:43,273,048...43,317,417
Ensembl chr 3:43,273,048...43,317,417 		JBrowse link
G Utp3 UTP3, small subunit processome component decreases expression ISO Etoposide results in decreased expression of UTP3 mRNA CTD PMID:24211769 NCBI chr14:19,515,716...19,517,370
Ensembl chr14:19,515,669...19,517,396 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions
decreases response to substance		 ISO [IL4 protein co-treated with VCAM1 protein] inhibits the reaction [Etoposide results in decreased folding of BAX protein]; [VCAM1 protein co-treated with IL4 protein] inhibits the reaction [Etoposide inhibits the reaction [BAX protein binds to BCL2L1 protein]]; [VCAM1 protein co-treated with IL4 protein] results in decreased susceptibility to Etoposide
VCAM1 protein results in decreased susceptibility to Etoposide		 CTD PMID:10620629 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vcan versican affects response to substance ISO VCAN protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions EXP Etoposide promotes the reaction [VDAC1 protein binds to VDAC1 protein] CTD PMID:20937774 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640 		JBrowse link
G Vdr vitamin D receptor multiple interactions
affects response to substance
increases expression		 ISO [[Etoposide results in increased expression of TP73 protein] which results in increased expression of VDR protein] which results in increased susceptibility to Calcitriol; TP73 protein affects the reaction [Etoposide results in increased expression of VDR mRNA]
VDR gene polymorphism affects the susceptibility to Etoposide; VDR intron polymorphism affects the susceptibility to Etoposide		 CTD PMID:12969965 PMID:15713801 PMID:17716971 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases response to substance ISO VEGFA mRNA results in decreased susceptibility to Etoposide CTD PMID:18494554 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vegfc vascular endothelial growth factor C multiple interactions
decreases response to substance		 ISO EDN1 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Etoposide]; PTGS2 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Etoposide] CTD PMID:24184161 NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 increases expression ISO Etoposide results in increased expression of VKORC1 mRNA CTD PMID:25270620 NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008 		JBrowse link
G Wif1 Wnt inhibitory factor 1 increases response to substance ISO WIF1 protein results in increased susceptibility to Etoposide CTD PMID:15389810 NCBI chr 7:56,548,060...56,618,364
Ensembl chr 7:56,548,053...56,618,360 		JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 affects response to substance ISO WIPI1 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846 		JBrowse link
G Wnt3a Wnt family member 3A increases response to substance ISO WNT3A protein results in increased susceptibility to Etoposide CTD PMID:19864107 NCBI chr10:44,034,174...44,078,366
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
G Wrn WRN RecQ like helicase increases response to substance ISO WRN gene mutant form results in increased susceptibility to Etoposide CTD PMID:10725663 NCBI chr16:58,763,517...58,898,604
Ensembl chr16:58,763,504...58,895,450 		JBrowse link
G Xaf1 XIAP associated factor 1 increases response to substance
increases expression
multiple interactions		 ISO XAF1 protein results in increased susceptibility to Etoposide
Etoposide results in increased expression of XAF1 mRNA; Etoposide results in increased expression of XAF1 protein
XAF1 protein affects the reaction [Etoposide results in decreased expression of MT2A protein]; XAF1 protein affects the reaction [Etoposide results in increased cleavage of PARP1 protein]		 CTD PMID:15843754 PMID:17570219 PMID:28507149 NCBI chr10:56,917,378...56,929,791
Ensembl chr10:56,917,121...56,929,770 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 multiple interactions
affects response to substance
increases expression		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Etoposide results in increased expression of XRCC1 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Etoposide results in increased expression of XRCC1 protein]; resveratrol inhibits the reaction [Etoposide results in increased expression of XRCC1 mRNA]; resveratrol inhibits the reaction [Etoposide results in increased expression of XRCC1 protein]; U 0126 inhibits the reaction [Etoposide results in increased expression of XRCC1 mRNA]; U 0126 inhibits the reaction [Etoposide results in increased expression of XRCC1 protein]
XRCC1 protein affects the susceptibility to Etoposide
Etoposide results in increased expression of XRCC1 mRNA; Etoposide results in increased expression of XRCC1 protein		 CTD PMID:26046675 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Xrcc2 X-ray repair cross complementing 2 multiple interactions
increases expression		 ISO BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC2 protein] CTD PMID:16417649 NCBI chr 4:9,423,873...9,502,980
Ensembl chr 4:9,423,898...9,442,482 		JBrowse link
G Xrcc3 X-ray repair cross complementing 3 multiple interactions
increases expression		 ISO BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC3 protein] CTD PMID:16417649 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 multiple interactions
decreases response to substance
increases expression		 ISO BRCA1 protein mutant form inhibits the reaction [Etoposide results in increased expression of XRCC4 protein]
XRCC4 results in decreased susceptibility to Etoposide		 CTD PMID:16417649 PMID:21785230 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 affects response to substance ISO XRCC5 protein affects the susceptibility to Etoposide CTD PMID:12384553 NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
G Zbtb24 zinc finger and BTB domain containing 24 decreases expression ISO Etoposide results in decreased expression of ZBTB24 mRNA CTD PMID:24211769 NCBI chr20:44,943,302...44,965,329
Ensembl chr20:44,947,297...44,963,963 		JBrowse link
G Zdhhc11 zinc finger, DHHC-type containing 11 affects response to substance ISO ZDHHC11 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 1:29,296,334...29,327,227
Ensembl chr 1:29,296,334...29,326,898 		JBrowse link
G Zfp202 zinc finger protein 202 decreases expression ISO Etoposide results in decreased expression of ZNF202 mRNA CTD PMID:24211769 NCBI chr 8:40,542,665...40,567,397
Ensembl chr 8:40,542,701...40,563,118 		JBrowse link
G Zfp365 zinc finger protein 365 increases expression ISO Etoposide results in increased expression of ZFP365 mRNA CTD PMID:25270620 NCBI chr20:20,666,240...20,689,734
Ensembl chr20:20,666,240...20,691,238 		JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 decreases expression ISO Etoposide results in decreased expression of ZFP36L1 mRNA CTD PMID:24211769 NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748 		JBrowse link
G Zfp637 zinc finger protein 637 affects response to substance ISO ZNF32 protein affects the susceptibility to Etoposide CTD PMID:16217747 NCBI chr 4:150,984,940...151,010,079
Ensembl chr 4:150,984,541...151,011,874 		JBrowse link
G Zfp94 zinc finger protein 94 decreases expression ISO Etoposide results in decreased expression of ZNF45 mRNA CTD PMID:24211769 NCBI chr 1:79,858,188...79,879,702
Ensembl chr 1:79,859,180...79,879,612 		JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression ISO Etoposide results in increased expression of ZMAT3 mRNA CTD PMID:29397400 NCBI chr 2:115,106,046...115,136,888
Ensembl chr 2:115,106,966...115,136,863 		JBrowse link
G Znf750 zinc finger protein 750 increases expression ISO Etoposide results in increased expression of ZFP750 mRNA CTD PMID:25270620 NCBI chr10:106,772,162...106,781,186
Ensembl chr10:106,772,669...106,781,200 		JBrowse link
Fargesin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO fargesin inhibits the reaction [Cadmium Chloride results in decreased expression of AHR protein] CTD PMID:35983679 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO fargesin inhibits the reaction [Cadmium Chloride results in increased expression of IL1B protein] CTD PMID:35983679 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO fargesin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; fargesin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein] CTD PMID:30919561 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO fargesin inhibits the reaction [Cadmium Chloride results in increased activity of MPO protein] CTD PMID:35983679 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO fargesin inhibits the reaction [Cadmium Chloride results in increased phosphorylation of NFKBIA protein] CTD PMID:35983679 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO fargesin inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RELA protein] CTD PMID:35983679 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO fargesin inhibits the reaction [Cadmium Chloride results in increased expression of TLR4 protein] CTD PMID:35983679 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO fargesin inhibits the reaction [Cadmium Chloride results in increased expression of TNF protein] CTD PMID:35983679 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
helioxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egfr epidermal growth factor receptor multiple interactions ISO [helioxanthin co-treated with Arecoline co-treated with 4-nitroquinolone-1-oxide] affects the localization of EGFR protein modified form; helioxanthin inhibits the reaction [[Arecoline co-treated with 4-nitroquinolone-1-oxide] results in increased phosphorylation of EGFR protein] CTD PMID:26464283 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [helioxanthin co-treated with Arecoline co-treated with 4-nitroquinolone-1-oxide] affects the expression of FOS protein; [helioxanthin co-treated with Arecoline co-treated with 4-nitroquinolone-1-oxide] affects the localization of FOS protein CTD PMID:26464283 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [helioxanthin co-treated with Arecoline co-treated with 4-nitroquinolone-1-oxide] affects the phosphorylation of MAPK1 protein; Dinoprostone affects the reaction [[helioxanthin co-treated with Arecoline co-treated with 4-nitroquinolone-1-oxide] affects the phosphorylation of MAPK1 protein] CTD PMID:26464283 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [helioxanthin co-treated with Arecoline co-treated with 4-nitroquinolone-1-oxide] affects the phosphorylation of MAPK3 protein; Dinoprostone affects the reaction [[helioxanthin co-treated with Arecoline co-treated with 4-nitroquinolone-1-oxide] affects the phosphorylation of MAPK3 protein] CTD PMID:26464283 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Dinoprostone inhibits the reaction [helioxanthin inhibits the reaction [[Arecoline co-treated with 4-nitroquinolone-1-oxide] results in increased expression of PTGS2 protein]]; helioxanthin inhibits the reaction [[Arecoline co-treated with 4-nitroquinolone-1-oxide] results in increased expression of PTGS2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [helioxanthin inhibits the reaction [[Arecoline co-treated with 4-nitroquinolone-1-oxide] results in increased expression of PTGS2 protein]] CTD PMID:26464283 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
isosilybin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha multiple interactions
decreases expression		 ISO isosilybin inhibits the reaction [T0901317 results in increased expression of ACACA mRNA]
isosilybin results in decreased expression of ACACA mRNA		 CTD PMID:36347319 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression ISO isosilybin results in increased expression of ACOX1 mRNA CTD PMID:36347319 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Cd36 CD36 molecule multiple interactions ISO isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CD36 mRNA] CTD PMID:36347319 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO isosilybin promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA] CTD PMID:36347319 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Fas Fas cell surface death receptor decreases expression
multiple interactions		 ISO isosilybin results in decreased expression of FAS mRNA
isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS protein]		 CTD PMID:36347319 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Mttp microsomal triglyceride transfer protein multiple interactions ISO isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MTTP mRNA]; isosilybin inhibits the reaction [T0901317 results in decreased expression of MTTP mRNA] CTD PMID:36347319 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239 		JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 decreases expression
multiple interactions		 ISO isosilybin results in decreased expression of PNPLA3 mRNA
isosilybin inhibits the reaction [T0901317 results in increased expression of PNPLA3 mRNA]		 CTD PMID:36347319 NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein] CTD PMID:36347319 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression
multiple interactions		 ISO isosilybin results in decreased expression of SREBF1 mRNA
isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 protein]; isosilybin inhibits the reaction [T0901317 results in increased expression of SREBF1 mRNA]; isosilybin inhibits the reaction [T0901317 results in increased expression of SREBF1 protein]		 CTD PMID:36347319 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
isosilybin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO isosilybin A results in increased expression of ABCA1 protein CTD PMID:26729088 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO isosilybin A promotes the reaction [APOA1 protein results in increased secretion of Cholesterol] CTD PMID:26729088 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Ccna1 cyclin A1 decreases expression ISO isosilybin A results in decreased expression of CCNA1 protein CTD PMID:18435416 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO isosilybin A results in decreased expression of CCNB1 protein CTD PMID:18435416 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO isosilybin A results in decreased expression of CCND1 protein CTD PMID:18435416 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO isosilybin A results in decreased expression of CCND3 protein CTD PMID:18435416 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO isosilybin A results in decreased expression of CCNE1 protein CTD PMID:18435416 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Cdc25a cell division cycle 25A decreases expression ISO isosilybin A results in decreased expression of CDC25A protein CTD PMID:18435416 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701 		JBrowse link
G Cdc25b cell division cycle 25B decreases expression ISO isosilybin A results in decreased expression of CDC25B protein CTD PMID:18435416 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272 		JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO isosilybin A results in decreased expression of CDC25C protein CTD PMID:18435416 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO isosilybin A results in decreased expression of CDK1 protein CTD PMID:18435416 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO isosilybin A results in decreased expression of CDK2 protein CTD PMID:18435416 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO isosilybin A results in decreased expression of CDK4 protein CTD PMID:18435416 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO isosilybin A results in increased expression of CDKN1B protein CTD PMID:18435416 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation ISO isosilybin A results in increased phosphorylation of CHEK2 protein CTD PMID:18435416 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Il4 interleukin 4 decreases secretion
decreases expression		 ISO isosilybin A results in decreased secretion of IL4 protein
isosilybin A results in decreased expression of IL4 mRNA		 CTD PMID:32284261 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il5 interleukin 5 decreases expression
decreases secretion		 ISO isosilybin A results in decreased expression of IL5 mRNA
isosilybin A results in decreased secretion of IL5 protein		 CTD PMID:32284261 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 multiple interactions ISO isosilybin A binds to and results in decreased activity of PTPN1 protein CTD PMID:30160205 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Skp2 S-phase kinase associated protein 2 decreases expression ISO isosilybin A results in decreased expression of SKP2 protein CTD PMID:18435416 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338 		JBrowse link
masoprocol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein affects binding EXP Masoprocol binds to AFP protein CTD PMID:23013281 PMID:25349334 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO Masoprocol results in decreased phosphorylation of AKT1 protein CTD PMID:19503098 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alk ALK receptor tyrosine kinase multiple interactions
decreases activity		 ISO Masoprocol affects the phosphorylation of and affects the activity of ALK protein mutant form
Masoprocol results in decreased activity of ALK protein		 CTD PMID:19503098 NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type multiple interactions
decreases activity		 ISO
EXP		 Masoprocol inhibits the reaction [ALOX12 protein results in increased chemical synthesis of 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid]
Masoprocol results in decreased activity of ALOX12 protein		 CTD PMID:3928952 PMID:6240459 PMID:9258337 PMID:17027136 PMID:23238474 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase multiple interactions
decreases activity		 EXP
ISO		 Masoprocol inhibits the reaction [[[Oxygen deficiency results in increased activity of ALOX15 protein] which results in increased chemical synthesis of 15-hydroxy-5,8,11,13-eicosatetraenoic acid] which results in decreased expression of KCNA5 mRNA]
Masoprocol results in decreased activity of ALOX15 protein
[Masoprocol results in decreased activity of ALOX15 protein] which results in increased abundance of 13-hydroxy-9,11-octadecadienoic acid		 CTD PMID:15574791 PMID:18984061 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase affects response to substance
decreases activity
multiple interactions		 ISO
EXP		 ALOX5 protein affects the susceptibility to Masoprocol
Masoprocol results in decreased activity of ALOX5 protein
Masoprocol inhibits the reaction [[CCL5 protein co-treated with Calcimycin] results in increased expression of ALOX5 mRNA]; Masoprocol inhibits the reaction [[CCL5 protein co-treated with Calcimycin] results in increased expression of ALOX5 protein]
[Masoprocol results in decreased activity of ALOX5 protein] which results in decreased chemical synthesis of Leukotriene B4; [Masoprocol results in decreased activity of ALOX5 protein] which results in increased abundance of 15-hydroxy-5,8,11,13-eicosatetraenoic acid; Masoprocol inhibits the reaction [ALOX5 protein promotes the reaction [lysophosphatidic acid results in increased abundance of Hydrogen Peroxide]]		 CTD PMID:2724698 PMID:2849922 PMID:3928952 PMID:6240459 PMID:10698703 More... NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Ar androgen receptor affects binding EXP Masoprocol binds to AR protein CTD PMID:14565775 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 ISO Masoprocol results in increased expression of BAX protein
MYC affects the reaction [Masoprocol results in increased expression of BAX protein]		 CTD PMID:15034932 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [Masoprocol co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of BID protein CTD PMID:17645780 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases activity		 ISO
EXP		 Masoprocol results in increased cleavage of CASP3 protein
Masoprocol inhibits the reaction [pentaacetyl geniposide results in increased cleavage of and results in increased activity of CASP3 protein]; Masoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of CASP3 protein]
acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Masoprocol results in increased activity of CASP3 protein]; Masoprocol inhibits the reaction [FASL protein results in increased activity of CASP3 protein]
[Masoprocol co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein		 CTD PMID:10203695 PMID:10653524 PMID:11470254 PMID:15034932 PMID:17645780 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression		 ISO [Masoprocol co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein
Masoprocol inhibits the reaction [FASL protein results in increased activity of CASP8 protein]
Masoprocol results in increased expression of CASP8 protein		 CTD PMID:10203695 PMID:17645780 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases activity ISO Masoprocol results in increased activity of CASP9 protein CTD PMID:15034932 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions EXP Masoprocol inhibits the reaction [[Calcimycin co-treated with CCL5 protein] results in increased secretion of Leukotriene B4]; Masoprocol inhibits the reaction [[CCL5 protein co-treated with Calcimycin] results in increased expression of ALOX5 mRNA]; Masoprocol inhibits the reaction [[CCL5 protein co-treated with Calcimycin] results in increased expression of ALOX5 protein] CTD PMID:18083043 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Masoprocol results in decreased expression of CCND1 protein CTD PMID:11953870 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cdh1 cadherin 1 decreases methylation
increases expression		 ISO Masoprocol results in decreased methylation of CDH1 promoter
Masoprocol results in increased expression of CDH1 mRNA; Masoprocol results in increased expression of CDH1 protein		 CTD PMID:18418215 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases methylation
increases expression		 ISO Masoprocol results in decreased methylation of CDKN2A promoter
Masoprocol results in increased expression of CDKN2A mRNA; Masoprocol results in increased expression of CDKN2A protein		 CTD PMID:18164318 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO Masoprocol inhibits the reaction [FN1 protein modified form results in increased expression of CHUK protein modified form] CTD PMID:17395008 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Cryab crystallin, alpha B multiple interactions EXP Masoprocol promotes the reaction [sodium arsenite results in increased expression of CRYAB mRNA]; Masoprocol promotes the reaction [sodium arsenite results in increased expression of CRYAB protein] CTD PMID:8591993 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO Masoprocol results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity ISO Masoprocol results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO Masoprocol results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions ISO Masoprocol inhibits the reaction [IGF1 protein results in increased phosphorylation of ERBB2 protein] CTD PMID:18645000 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Masoprocol binds to and results in increased activity of ESR1 protein CTD PMID:19063592 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Masoprocol results in increased expression of FAS protein CTD PMID:17645780 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand multiple interactions ISO
EXP		 Masoprocol inhibits the reaction [FASL protein results in increased activity of CASP3 protein]; Masoprocol inhibits the reaction [FASL protein results in increased activity of CASP8 protein]
Masoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of FASLG protein]		 CTD PMID:10203695 PMID:17651887 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO Masoprocol inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of MMP13 protein]; Masoprocol inhibits the reaction [FN1 protein modified form results in increased expression of CHUK protein modified form]; Masoprocol inhibits the reaction [FN1 protein modified form results in increased expression of MAPK8 protein modified form]; Masoprocol inhibits the reaction [FN1 protein modified form results in increased expression of MAPK9 protein modified form]; Masoprocol inhibits the reaction [FN1 protein modified form results in increased expression of NFKBIA protein modified form]; Masoprocol inhibits the reaction [FN1 protein modified form results in increased expression of RELA protein modified form]; Masoprocol inhibits the reaction [FN1 protein modified form results in increased phosphorylation of MAPK1 protein]; Masoprocol inhibits the reaction [FN1 protein modified form results in increased phosphorylation of MAPK3 protein] CTD PMID:17395008 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Masoprocol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [FOS protein co-treated with JUN protein]] CTD PMID:10692565 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fpr1 formyl peptide receptor 1 decreases activity ISO Masoprocol results in decreased activity of FPR1 protein CTD PMID:17520823 NCBI chr 1:58,745,019...58,756,776
Ensembl chr 1:58,747,246...58,756,559 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP
ISO		 Masoprocol results in increased expression of HMOX1 mRNA; Masoprocol results in increased expression of HMOX1 protein CTD PMID:18852027 PMID:23942037 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions
increases expression
increases activity		 ISO 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid inhibits the reaction [Masoprocol results in increased activity of HSD11B2 protein]; 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid inhibits the reaction [Masoprocol results in increased expression of HSD11B2 mRNA]; [Masoprocol co-treated with 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid] results in decreased expression of HSD11B2 protein; [Masoprocol co-treated with Leukotriene B4] results in decreased expression of HSD11B2 protein; Leukotriene B4 inhibits the reaction [Masoprocol results in increased activity of HSD11B2 protein]; Masoprocol inhibits the reaction [Progesterone results in decreased activity of HSD11B2 protein]; Masoprocol promotes the reaction [Mifepristone results in increased activity of HSD11B2 protein] CTD PMID:10377029 PMID:18032417 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO Masoprocol inhibits the reaction [IGF1 protein promotes the reaction [IGF1R protein results in increased phosphorylation of and results in increased activity of IGF1R protein]]; Masoprocol inhibits the reaction [IGF1 protein results in increased phosphorylation of ERBB2 protein]; Masoprocol inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein] CTD PMID:18491370 PMID:18645000 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions
decreases activity		 ISO Masoprocol inhibits the reaction [Dihydrotestosterone results in increased expression of IGF1R mRNA]; Masoprocol inhibits the reaction [Dihydrotestosterone results in increased expression of IGF1R protein]; Masoprocol inhibits the reaction [IGF1 protein promotes the reaction [IGF1R protein results in increased phosphorylation of and results in increased activity of IGF1R protein]]; Masoprocol inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein]
Masoprocol results in decreased activity of IGF1R protein		 CTD PMID:18491370 PMID:18645000 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases response to substance		 ISO Masoprocol inhibits the reaction [Eicosapentaenoic Acid inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]]; Masoprocol inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Masoprocol inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]
Masoprocol results in decreased susceptibility to IL1B protein
Masoprocol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]		 CTD PMID:8186192 PMID:12573452 PMID:21211511 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Masoprocol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:8186192 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO Masoprocol inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions		 ISO Masoprocol results in decreased expression of JUN mRNA
Masoprocol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [FOS protein co-treated with JUN protein]]		 CTD PMID:10692565 PMID:15034932 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 multiple interactions EXP Masoprocol inhibits the reaction [[[Oxygen deficiency results in increased activity of ALOX15 protein] which results in increased chemical synthesis of 15-hydroxy-5,8,11,13-eicosatetraenoic acid] which results in decreased expression of KCNA5 mRNA] CTD PMID:18984061 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697 		JBrowse link
G Krt1 keratin 1 multiple interactions ISO Masoprocol inhibits the reaction [Calcium results in increased expression of KRT1 mRNA] CTD PMID:12069687 NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP Masoprocol inhibits the reaction [LHB protein results in increased abundance of Cyclic AMP]; Masoprocol inhibits the reaction [LHB protein results in increased abundance of Pregnenolone]; Masoprocol inhibits the reaction [LHB protein results in increased abundance of Testosterone] CTD PMID:6430271 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation		 ISO Masoprocol inhibits the reaction [FN1 protein modified form results in increased phosphorylation of MAPK1 protein]
Masoprocol results in decreased phosphorylation of MAPK1 protein		 CTD PMID:17395008 PMID:19503098 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions		 ISO Masoprocol results in decreased phosphorylation of MAPK3 protein
Masoprocol inhibits the reaction [FN1 protein modified form results in increased phosphorylation of MAPK3 protein]		 CTD PMID:17395008 PMID:19503098 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Masoprocol inhibits the reaction [FN1 protein modified form results in increased expression of MAPK8 protein modified form] CTD PMID:17395008 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO Masoprocol inhibits the reaction [FN1 protein modified form results in increased expression of MAPK9 protein modified form] CTD PMID:17395008 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions ISO Masoprocol inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of MMP13 protein]; Masoprocol inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Masoprocol inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]; Masoprocol inhibits the reaction [TNF protein results in increased expression of MMP13 mRNA]; Masoprocol inhibits the reaction [TNF protein results in increased expression of MMP13 protein] CTD PMID:17395008 PMID:21211511 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression
multiple interactions		 ISO Masoprocol results in increased expression of MYC protein
MYC affects the reaction [Masoprocol results in increased expression of BAX protein]; MYC affects the reaction [Masoprocol results in increased expression of MYC protein]; MYC affects the reaction [Masoprocol results in increased expression of TP53 protein]		 CTD PMID:15034932 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP Masoprocol affects the localization of and results in increased activity of NFE2L2 protein CTD PMID:18852027 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Masoprocol inhibits the reaction [FN1 protein modified form results in increased expression of NFKBIA protein modified form] CTD PMID:17395008 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Ngf nerve growth factor multiple interactions EXP Masoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]; Masoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein] CTD PMID:17651887 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Ngfr nerve growth factor receptor multiple interactions EXP Masoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR mRNA]; Masoprocol inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR protein] CTD PMID:17651887 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO Masoprocol inhibits the reaction [Ritonavir results in decreased expression of NOS3 mRNA] CTD PMID:22037733 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions ISO Masoprocol inhibits the reaction [Benzoyl Peroxide results in increased activity of ODC1 protein] CTD PMID:2105358 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Otc ornithine transcarbamylase multiple interactions EXP Masoprocol promotes the reaction [PRL protein results in increased activity of OTC protein] CTD PMID:3097147 NCBI chr  X:12,453,834...12,529,954
Ensembl chr  X:12,453,834...12,566,918 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO Masoprocol affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein] CTD PMID:25770929 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions ISO Masoprocol inhibits the reaction [POR protein affects the reaction [Benzo(a)pyrene results in increased chemical synthesis of benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide-DNA]] CTD PMID:28111842 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Prl prolactin multiple interactions EXP Masoprocol promotes the reaction [PRL protein results in increased activity of OTC protein] CTD PMID:3097147 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Masoprocol inhibits the reaction [Eicosapentaenoic Acid inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]]; Masoprocol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:7575673 PMID:12573452 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases phosphorylation ISO Masoprocol results in decreased phosphorylation of RB1 protein CTD PMID:18164318 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Masoprocol inhibits the reaction [FN1 protein modified form results in increased expression of RELA protein modified form] CTD PMID:17395008 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Shbg sex hormone binding globulin affects binding ISO Masoprocol binds to SHBG protein CTD PMID:25349334 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions EXP Masoprocol inhibits the reaction [TSHB protein results in increased expression of SLC5A5 mRNA] CTD PMID:17962351 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO Masoprocol inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; Masoprocol inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]; Masoprocol inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA] CTD PMID:8760145 PMID:12031898 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases phosphorylation ISO Masoprocol results in decreased phosphorylation of STAT3 protein CTD PMID:19503098 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP Masoprocol inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TGFB1 mRNA] CTD PMID:19194550 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases response to substance		 ISO Masoprocol inhibits the reaction [TNF protein results in increased expression of MMP13 mRNA]; Masoprocol inhibits the reaction [TNF protein results in increased expression of MMP13 protein]; Masoprocol inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]
Masoprocol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]
Masoprocol results in decreased susceptibility to TNF protein		 CTD PMID:8186192 PMID:8760145 PMID:21211511 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [Masoprocol co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of BID protein; [Masoprocol co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP10 protein; [Masoprocol co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein; [Masoprocol co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:17645780 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression		 ISO MYC affects the reaction [Masoprocol results in increased expression of TP53 protein] CTD PMID:15034932 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions EXP Masoprocol inhibits the reaction [[Melitten results in increased activity of TRPV1 protein] which results in increased transport of Calcium] CTD PMID:21453681 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions EXP Masoprocol inhibits the reaction [TSHB protein results in increased expression of SLC5A5 mRNA] CTD PMID:17962351 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of Masoprocol CTD PMID:14557274 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of Masoprocol CTD PMID:14557274 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO Masoprocol inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of VEGFA mRNA]; Masoprocol inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased secretion of VEGFA protein] CTD PMID:17520823 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
nordihydroguaiaretic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha increases phosphorylation
decreases expression 		EXP NDGA increases phosphorylation in liver of high fructose fed rats
NDGA decreases expression of mRNA in liver of high fructose fed rats		 RGD PMID:26394137 PMID:26394137 RGD:329955565, RGD:329955565 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acacb acetyl-CoA carboxylase beta decreases expression EXP NDGA decreases expression of Acacb protein in liver of high fructose fed rats RGD PMID:26394137 RGD:329955565 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655 		JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression EXP NDGA increases expression of mRNA in liver of high fructose fed rats RGD PMID:26394137 RGD:329955565 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation EXP NDGA increases phosphorylation in liver of high fructose fed rats RGD PMID:26394137 RGD:329955565 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Cd36 CD36 molecule increases expression EXP NDGA increases expression of mRNA in liver of high fructose fed rats RGD PMID:26394137 RGD:329955565 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression EXP NDGA increases expression of mRNA in liver of high fructose fed rats RGD PMID:26394137 RGD:329955565 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 decreases expression EXP NDGA decreases expression of mRNA in liver of high fructose fed rats RGD PMID:26394137 RGD:329955565 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428 		JBrowse link
G Fabp2 fatty acid binding protein 2 increases expression EXP NDGA increases expression of mRNA in liver of high fructose fed rats RGD PMID:26394137 RGD:329955565 NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089 		JBrowse link
G Fasn fatty acid synthase decreases expression EXP NDGA decreases expression of mRNA in liver of high fructose fed rats RGD PMID:26394137 RGD:329955565 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression EXP NDGA decreases expression of mRNA in liver of high fructose fed rats RGD PMID:26394137 RGD:329955565 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha increases phosphorylation EXP NDGA increases phosphorylation in liver of high fructose fed rats RGD PMID:26394137 RGD:329955565 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation EXP NDGA increases phosphorylation in liver of high fructose fed rats RGD PMID:26394137 RGD:329955565 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Mlxipl MLX interacting protein-like decreases expression EXP NDGA decreases expression of mRNA in liver of high fructose fed rats RGD PMID:26394137 RGD:329955565 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112 		JBrowse link
G Mlycd malonyl-CoA decarboxylase increases expression EXP NDGA increases expression of Mlycd protein in liver of high fructose fed rats RGD PMID:26394137 RGD:329955565 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793 		JBrowse link
G Pklr pyruvate kinase L/R decreases expression EXP NDGA decreases expression of mRNA in liver of high fructose fed rats RGD PMID:26394137 RGD:329955565 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression EXP NDGA increases expression of Ppara protein in liver of high fructose fed rats RGD PMID:26394137 RGD:329955565 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 increases phosphorylation EXP NDGA increases phosphorylation in liver of high fructose fed rats RGD PMID:26394137 RGD:329955565 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543 		JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP NDGA decreases expression of mRNA, protein in liver of high fructose fed rats RGD PMID:26394137 RGD:329955565 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression EXP NDGA decreases expression of mRNA in liver of high fructose fed rats RGD PMID:26394137 RGD:329955565 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
Phyllanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad2 SMAD family member 2 multiple interactions ISO phyllanthin inhibits the reaction [Carbon Tetrachloride results in increased expression of SMAD2 protein] CTD PMID:26337812 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO phyllanthin inhibits the reaction [Carbon Tetrachloride results in increased expression of SMAD3 protein] CTD PMID:26337812 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO phyllanthin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein] CTD PMID:26337812 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 multiple interactions ISO phyllanthin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFBR1 protein] CTD PMID:26337812 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
picropodophyllotoxin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO picropodophyllin inhibits the reaction [Cadmium Chloride results in increased cleavage of AKT1 protein] CTD PMID:25118938 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO picropodophyllin results in decreased expression of BIRC5 protein CTD PMID:16166596 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases activity ISO picropodophyllin results in decreased activity of CDK1 protein CTD PMID:16166596 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO [picropodophyllin results in decreased activity of IGF1R protein] inhibits the reaction [Cadmium Chloride results in decreased activity of FOXO3 protein]; [picropodophyllin results in decreased activity of IGF1R protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of FOXO3 protein] CTD PMID:23673518 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO [picropodophyllin co-treated with IGF1 protein] results in increased expression of TNF mRNA; [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of IL1B mRNA]; [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of IL6 mRNA]; [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of TLR4 mRNA]; [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of TNF mRNA]; picropodophyllin inhibits the reaction [IGF1 protein results in decreased expression of TLR4 mRNA]; picropodophyllin inhibits the reaction [IGF1 protein results in increased expression of IL1B mRNA]; picropodophyllin promotes the reaction [IGF1 protein results in increased expression of IL6 mRNA] CTD PMID:21371294 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases activity
multiple interactions		 ISO picropodophyllin results in decreased activity of IGF1R protein
picropodophyllin binds to and results in decreased activity of IGF1R protein
[picropodophyllin results in decreased activity of IGF1R protein] inhibits the reaction [Cadmium Chloride results in decreased activity of FOXO3 protein]; [picropodophyllin results in decreased activity of IGF1R protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of FOXO3 protein]		 CTD PMID:16166596 PMID:21371294 PMID:23673518 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of IL1B mRNA]; [picropodophyllin co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA; picropodophyllin inhibits the reaction [IGF1 protein results in increased expression of IL1B mRNA] CTD PMID:21371294 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression		 ISO [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of IL6 mRNA]; [picropodophyllin co-treated with Lipopolysaccharides] results in increased expression of IL6 mRNA; picropodophyllin promotes the reaction [IGF1 protein results in increased expression of IL6 mRNA]
picropodophyllin results in increased expression of IL6 mRNA		 CTD PMID:21371294 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO picropodophyllin results in decreased phosphorylation of MAPK1 protein CTD PMID:16166596 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO picropodophyllin results in decreased phosphorylation of MAPK3 protein CTD PMID:16166596 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO picropodophyllin results in decreased expression of MCL1 protein CTD PMID:16166596 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO picropodophyllin inhibits the reaction [[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with Dichlorodiphenyl Dichloroethylene co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Hexachlorobenzene] results in increased activity of MMP2 protein] CTD PMID:33571556 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Notch1 notch receptor 1 multiple interactions ISO picropodophyllin inhibits the reaction [Cadmium Chloride results in increased cleavage of NOTCH1 protein] CTD PMID:25118938 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO picropodophyllin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of TLR4 mRNA]; picropodophyllin inhibits the reaction [IGF1 protein results in decreased expression of TLR4 mRNA] CTD PMID:21371294 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [picropodophyllin co-treated with IGF1 protein] results in increased expression of TNF mRNA; [picropodophyllin co-treated with Lipopolysaccharides] inhibits the reaction [IGF1 protein results in decreased expression of TNF mRNA] CTD PMID:21371294 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
podophyllotoxin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp2 caspase 2 increases activity ISO Podophyllotoxin results in increased activity of CASP2 protein CTD PMID:21916509 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Casp3 caspase 3 increases activity ISO Podophyllotoxin results in increased activity of CASP3 protein CTD PMID:21916509 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases activity ISO Podophyllotoxin results in increased activity of CASP9 protein CTD PMID:21916509 PMID:33722735 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Podophyllotoxin results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Podophyllotoxin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions ISO Podophyllotoxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein] CTD PMID:9270009 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Podophyllotoxin results in increased cleavage of PARP1 protein CTD PMID:21916509 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
silibinin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO Silybin results in increased expression of ABCA1 protein CTD PMID:26729088 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions EXP Silybin affects the localization of and affects the activity of ABCB11 protein CTD PMID:15763547 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO Silybin inhibits the reaction [ABCB1 protein results in decreased uptake of Daunorubicin]; Silybin promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Daunorubicin]] CTD PMID:34217736 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions
increases phosphorylation		 ISO Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased phosphorylation of ACACA protein]
Silybin results in increased phosphorylation of ACACA protein		 CTD PMID:25294820 PMID:25559859 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acly ATP citrate lyase decreases phosphorylation ISO Silybin results in decreased phosphorylation of ACLY protein CTD PMID:25294820 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320 		JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions EXP Silybin inhibits the reaction [ferric ammonium citrate results in increased expression of ACP5 protein] CTD PMID:36087815 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Adipor2 adiponectin receptor 2 increases expression EXP silymarin (silibinin) increases expression of adipor2 mRNA and protein in epididymal white adipose tissue of alcohol fed rats RGD PMID:26115886 RGD:25330099 NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355 		JBrowse link
G Agpat3 1-acylglycerol-3-phosphate O-acyltransferase 3 multiple interactions EXP Silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in increased expression of AGPAT3 mRNA] CTD PMID:28619387 NCBI chr20:10,330,960...10,415,358
Ensembl chr20:10,384,507...10,415,358 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO Silybin results in decreased activity of AKR1C3 protein CTD PMID:19007764 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of AKT1 protein] CTD PMID:25559859 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO Silybin inhibits the reaction [ferric ammonium citrate results in decreased expression of and results in decreased activity of ALPL protein] CTD PMID:36087815 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Amacr alpha-methylacyl-CoA racemase decreases expression ISO Silybin results in decreased expression of AMACR protein CTD PMID:25294820 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255 		JBrowse link
G Apoa5 apolipoprotein A5 multiple interactions EXP Silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of APOA5 mRNA] CTD PMID:28619387 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816 		JBrowse link
G Asl argininosuccinate lyase multiple interactions EXP Silybin inhibits the reaction [[Isoniazid co-treated with Zidovudine] results in increased activity of ASL protein] CTD PMID:28619387 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662 		JBrowse link
G Atm ATM serine/threonine kinase multiple interactions ISO Silybin results in increased phosphorylation of and results in increased activity of ATM protein CTD PMID:16777994 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Silybin inhibits the reaction [Acetaldehyde results in increased expression of BAX protein]; Silybin inhibits the reaction [Ethanol results in increased expression of BAX protein]; Silybin inhibits the reaction [Mitomycin affects the localization of BAX protein]; Silybin inhibits the reaction [Staurosporine promotes the reaction [Acetaldehyde results in increased expression of BAX protein]] CTD PMID:19834285 PMID:35158046 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions		 ISO Silybin results in decreased expression of BCL2 mRNA
[Silybin co-treated with Arsenic Trioxide] results in decreased expression of BCL2 mRNA; Silybin inhibits the reaction [Acetaldehyde results in decreased expression of BCL2 protein]; Silybin inhibits the reaction [Ethanol results in decreased expression of BCL2 protein]; Silybin inhibits the reaction [Mitomycin affects the expression of BCL2]; Silybin inhibits the reaction [Staurosporine promotes the reaction [Acetaldehyde results in decreased expression of BCL2 protein]]		 CTD PMID:19834285 PMID:21969006 PMID:35158046 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
increases cleavage
affects localization		 ISO benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [Silybin results in increased cleavage of BID protein]; Caffeine inhibits the reaction [Silybin results in increased cleavage of BID protein]; pifithrin inhibits the reaction [Silybin results in increased cleavage of BID protein]
Silybin affects the localization of BID protein modified form		 CTD PMID:16777994 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO [Silybin co-treated with Arsenic Trioxide] results in decreased expression of BIRC5 mRNA CTD PMID:21969006 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Car9 carbonic anhydrase 9 decreases expression
multiple interactions		 ISO Silybin results in decreased expression of CA9 mRNA
Arsenic Trioxide promotes the reaction [Silybin results in decreased expression of CA9 mRNA]		 CTD PMID:21969006 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838 		JBrowse link
G Casp2 caspase 2 multiple interactions ISO benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [Silybin results in increased cleavage of and results in increased activity of CASP2 protein]; Caffeine inhibits the reaction [Silybin results in increased cleavage of and results in increased activity of CASP2 protein]; pifithrin inhibits the reaction [Silybin results in increased cleavage of and results in increased activity of CASP2 protein]; Silybin results in increased cleavage of and results in increased activity of CASP2 protein CTD PMID:16777994 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Casp3 caspase 3 increases expression
increases activity
multiple interactions		 ISO Silybin results in increased expression of CASP3 mRNA
Silybin results in increased activity of CASP3 protein
Arsenic Trioxide promotes the reaction [Silybin results in increased activity of CASP3 protein]; benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [Silybin results in increased cleavage of and results in increased activity of CASP3 protein]; Caffeine inhibits the reaction [Silybin results in increased cleavage of and results in increased activity of CASP3 protein]; pifithrin inhibits the reaction [Silybin results in increased cleavage of and results in increased activity of CASP3 protein]; Silybin inhibits the reaction [Acetaldehyde results in increased cleavage of CASP3 protein]; Silybin inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]; Silybin promotes the reaction [Arsenic Trioxide results in increased expression of CASP3 mRNA]; Silybin results in increased cleavage of and results in increased activity of CASP3 protein		 CTD PMID:16777994 PMID:21969006 PMID:35158046 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [Silybin results in increased cleavage of and results in increased activity of CASP8 protein]; pifithrin inhibits the reaction [Silybin results in increased cleavage of and results in increased activity of CASP8 protein]; Silybin results in increased cleavage of and results in increased activity of CASP8 protein CTD PMID:16777994 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [Silybin results in increased cleavage of and results in increased activity of CASP9 protein]; Caffeine inhibits the reaction [Silybin results in increased cleavage of and results in increased activity of CASP9 protein]; pifithrin inhibits the reaction [Silybin results in increased cleavage of and results in increased activity of CASP9 protein]; Silybin results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:16777994 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions EXP Silybin inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased activity of CAT protein]; Silybin inhibits the reaction [Arsenic results in decreased activity of CAT protein] CTD PMID:22229868 PMID:35752206 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccna1 cyclin A1 decreases expression ISO Silybin results in decreased expression of CCNA1 protein CTD PMID:18435416 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157 		JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCNA2 protein] CTD PMID:25559859 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnb1 cyclin B1 multiple interactions
decreases expression		 ISO Silybin inhibits the reaction [Arsenic results in increased expression of CCNB1]
Silybin results in decreased expression of CCNB1 protein		 CTD PMID:18435416 PMID:25868784 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression		 ISO Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCND1 protein]
Silybin results in decreased expression of CCND1 protein
[Silybin co-treated with Arsenic] results in decreased expression of CCND1 protein		 CTD PMID:16788158 PMID:18435416 PMID:25559859 PMID:25868784 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd3 cyclin D3 multiple interactions
decreases expression		 ISO [Silybin co-treated with Arsenic] results in decreased expression of CCND3 protein
Silybin results in decreased expression of CCND3 protein		 CTD PMID:18435416 PMID:25868784 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Silybin results in decreased expression of CCNE1 protein CTD PMID:18435416 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Cdc25a cell division cycle 25A decreases expression ISO Silybin results in decreased expression of CDC25A protein CTD PMID:18435416 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701 		JBrowse link
G Cdc25b cell division cycle 25B decreases expression ISO Silybin results in decreased expression of CDC25B protein CTD PMID:18435416 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272 		JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO Silybin results in decreased expression of CDC25C protein CTD PMID:18435416 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
decreases expression		 ISO Silybin inhibits the reaction [Arsenic results in increased expression of CDK1 protein]
Silybin results in decreased expression of CDK1 protein		 CTD PMID:18435416 PMID:25868784 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
decreases expression		 ISO [Silybin co-treated with Arsenic] results in decreased expression of CDK2 protein
Silybin results in decreased expression of CDK2 protein		 CTD PMID:18435416 PMID:25868784 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions
decreases expression		 ISO [Silybin co-treated with Arsenic] results in decreased expression of CDK4 protein
Silybin results in decreased expression of CDK4 protein		 CTD PMID:18435416 PMID:25868784 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdk6 cyclin-dependent kinase 6 multiple interactions ISO [Silybin co-treated with Arsenic] results in decreased expression of CDK6 protein CTD PMID:25868784 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases cleavage		 ISO [Silybin co-treated with Arsenic] results in increased expression of CDKN1A protein; benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [Silybin results in increased cleavage of CDKN1A protein] CTD PMID:16777994 PMID:25868784 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases expression		 ISO Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CDKN1B protein]
Silybin results in increased expression of CDKN1B protein
[Silybin co-treated with Arsenic] results in increased expression of CDKN1B protein		 CTD PMID:18435416 PMID:25559859 PMID:25868784 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CEBPA protein] CTD PMID:25559859 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation
multiple interactions		 ISO Silybin results in increased phosphorylation of CHEK2 protein
Caffeine inhibits the reaction [Silybin results in increased phosphorylation of CHEK2 protein]		 CTD PMID:16777994 PMID:18435416 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP [Silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A1 mRNA] CTD PMID:16169303 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Ctsb cathepsin B multiple interactions ISO [Arsenic Trioxide co-treated with Silybin] results in decreased expression of CTSB mRNA CTD PMID:21969006 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions EXP Silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of CYB5A mRNA] CTD PMID:28619387 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535 		JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions EXP Silybin inhibits the reaction [sodium arsenite results in increased expression of CYBB] CTD PMID:24062023 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity ISO Silybin results in decreased activity of CYP2C8 protein CTD PMID:28457856
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
decreases activity		 ISO Silybin inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]
Silybin results in decreased activity of CYP3A4 protein		 CTD PMID:15155549 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO DDIT3 affects the reaction [Silybin results in increased expression of TNFRSF10B] CTD PMID:19939880 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 multiple interactions ISO Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of DLK1 mRNA] CTD PMID:25559859 NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522 		JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO Silybin inhibits the reaction [Acetaldehyde results in increased expression of DNM1L protein]; Silybin inhibits the reaction [Ethanol results in increased expression of DNM1L protein] CTD PMID:35158046 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482 		JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions		 ISO Silybin results in increased expression of EGR1 protein
EGR1 mutant form inhibits the reaction [Silybin results in increased expression of GDF15 protein]		 CTD PMID:24440808 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP
ISO		 Silybin results in increased activity of [ESR1 protein binds to ESR2 protein] CTD PMID:16076518 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO
EXP		 Silybin results in increased activity of [ESR1 protein binds to ESR2 protein] CTD PMID:16076518 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Faah fatty acid amide hydrolase multiple interactions
decreases activity		 EXP Silybin inhibits the reaction [FAAH protein results in increased metabolism of and results in decreased activity of anandamide]
Silybin results in decreased activity of FAAH protein		 CTD PMID:37245739 NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677 		JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FABP4 protein] CTD PMID:25559859 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fasn fatty acid synthase multiple interactions
decreases expression		 ISO Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN protein]
Silybin results in decreased expression of FASN protein		 CTD PMID:25294820 PMID:25559859 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions ISO Silybin inhibits the reaction [Urethane results in increased secretion of FGF2 protein] CTD PMID:16788158 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO Silybin inhibits the reaction [Acetaldehyde results in decreased expression of FTH1 mRNA]; Silybin inhibits the reaction [Acetaldehyde results in decreased expression of FTH1 protein]; Silybin inhibits the reaction [Ethanol results in decreased expression of FTH1 mRNA]; Silybin inhibits the reaction [Ethanol results in decreased expression of FTH1 protein] CTD PMID:35595033 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions EXP Silybin inhibits the reaction [Arsenic results in decreased activity of G6PD protein] CTD PMID:22229868 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression
multiple interactions		 ISO Silybin results in increased expression of GDF15 mRNA; Silybin results in increased expression of GDF15 protein
EGR1 mutant form inhibits the reaction [Silybin results in increased expression of GDF15 protein]; GDF15 mutant form inhibits the reaction [Silybin results in increased cleavage of PARP1 protein]; pyrazolanthrone promotes the reaction [Silybin results in increased expression of GDF15 protein]; SB 203580 inhibits the reaction [Silybin results in increased expression of GDF15 protein]		 CTD PMID:24440808 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP
ISO		 Silybin inhibits the reaction [Isoniazid promotes the reaction [Zidovudine results in increased activity of GPT protein]]
Silybin inhibits the reaction [Acetaldehyde results in increased activity of GPT protein]; Silybin inhibits the reaction [Ethanol results in increased activity of and results in increased secretion of GPT protein]		 CTD PMID:28619387 PMID:35158046 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP Silybin inhibits the reaction [Arsenic results in decreased activity of GSR protein] CTD PMID:22229868 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases phosphorylation		 ISO Caffeine inhibits the reaction [Silybin results in increased phosphorylation of H2AX protein] CTD PMID:16777994 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO Silybin results in decreased expression of HMGCR protein CTD PMID:25294820 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP Silybin inhibits the reaction [sodium arsenite results in decreased expression of HMOX1] CTD PMID:24062023 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Ifng interferon gamma multiple interactions ISO Silybin inhibits the reaction [IL1B protein results in increased expression of IFNG mRNA]; Silybin inhibits the reaction [IL1B protein results in increased secretion of IFNG protein] CTD PMID:28914761 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Silybin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein] CTD PMID:33839235 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Silybin inhibits the reaction [IL1B protein results in increased expression of IFNG mRNA]; Silybin inhibits the reaction [IL1B protein results in increased expression of TNF mRNA]; Silybin inhibits the reaction [IL1B protein results in increased secretion of IFNG protein]; Silybin inhibits the reaction [IL1B protein results in increased secretion of IL2 protein]; Silybin inhibits the reaction [IL1B protein results in increased secretion of TNF protein] CTD PMID:28914761 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO Silybin inhibits the reaction [IL1B protein results in increased secretion of IL2 protein] CTD PMID:28914761 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Silybin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:33839235 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ins1 insulin 1 multiple interactions ISO Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CDKN1B protein]; Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of DLK1 mRNA]; Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of KLF2 mRNA]; Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased phosphorylation of ACACA protein]; Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCNA2 protein]; Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CCND1 protein]; Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CEBPA protein]; Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FABP4 protein]; Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of FASN protein]; Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of KLF4 mRNA]; Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of KLF5 mRNA]; Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of LPIN1 protein]; Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein]; Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of AKT1 protein]; Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of MAPK1 protein]; Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of MAPK3 protein]; Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RB1 protein]; Silybin inhibits the reaction [INS1 protein affects the localization of SLC2A4 protein]; Silybin inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose] CTD PMID:18591783 PMID:25559859 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO silibinin decreases expression and phosphorylation of JAK2 protein in breast epithelium RGD PMID:28440514 RGD:149735360 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions EXP Silybin inhibits the reaction [sodium arsenite results in increased expression of KEAP1] CTD PMID:24062023 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Klf2 KLF transcription factor 2 multiple interactions ISO Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of KLF2 mRNA] CTD PMID:25559859 NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944 		JBrowse link
G Klf4 KLF transcription factor 4 multiple interactions ISO Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of KLF4 mRNA]
silibinin inhibits the reaction [angiotensin II increases expression of KLF4 protein in vascular smooth muscle cells] 		CTD
RGD		 PMID:25559859 PMID:29127880 RGD:155230825 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Klf5 KLF transcription factor 5 multiple interactions ISO Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of KLF5 mRNA] CTD PMID:25559859 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445 		JBrowse link
G Lpin1 lipin 1 multiple interactions ISO Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of LPIN1 protein] CTD PMID:25559859 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of MAPK1 protein] CTD PMID:25559859 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of MAPK3 protein] CTD PMID:25559859 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions		 ISO Silybin results in increased phosphorylation of MAPK8 protein
pifithrin inhibits the reaction [Silybin results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Silybin results in increased phosphorylation of MAPK8 protein]		 CTD PMID:16777994 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation		 ISO pifithrin inhibits the reaction [Silybin results in increased phosphorylation of MAPK9 protein]; pyrazolanthrone inhibits the reaction [Silybin results in increased phosphorylation of MAPK9 protein] CTD PMID:16777994 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mfn1 mitofusin 1 multiple interactions ISO Silybin inhibits the reaction [Acetaldehyde results in decreased expression of MFN1 protein]; Silybin inhibits the reaction [Ethanol results in decreased expression of MFN1 protein] CTD PMID:35158046 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase multiple interactions ISO Silybin results in increased expression of and results in increased activity of MGMT protein CTD PMID:16950796 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
G Mmp14 matrix metallopeptidase 14 multiple interactions ISO [Arsenic Trioxide co-treated with Silybin] results in decreased expression of MMP14 mRNA; Arsenic Trioxide inhibits the reaction [Silybin results in increased expression of MMP14 mRNA] CTD PMID:21969006 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression
multiple interactions		 ISO
EXP		 Silybin results in increased expression of MMP2 mRNA
[Silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of MMP2 mRNA]
[Arsenic Trioxide co-treated with Silybin] results in decreased activity of MMP2 protein; [Arsenic Trioxide co-treated with Silybin] results in decreased expression of MMP2 mRNA; [Silybin co-treated with Arsenic] results in decreased expression of MMP2; Silybin promotes the reaction [Arsenic Trioxide results in decreased expression of MMP2 mRNA]		 CTD PMID:16169303 PMID:21969006 PMID:25868784 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions
decreases activity		 ISO Silybin results in decreased expression of MMP9 mRNA
[Arsenic Trioxide co-treated with Silybin] results in decreased expression of MMP9 mRNA; [Silybin co-treated with Arsenic Trioxide] results in decreased activity of MMP9 protein
Silybin results in decreased activity of MMP9 protein		 CTD PMID:21969006 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Silybin results in decreased expression of MYC protein CTD PMID:27746612 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nat2 N-acetyltransferase 2 multiple interactions EXP Silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of NAT2 mRNA] CTD PMID:28619387 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Ncoa4 nuclear receptor coactivator 4 multiple interactions ISO Silybin inhibits the reaction [Acetaldehyde results in increased expression of NCOA4 mRNA]; Silybin inhibits the reaction [Ethanol results in increased expression of NCOA4 mRNA] CTD PMID:35595033 NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641
Ensembl chr16:7,366,542...7,409,641 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP Silybin inhibits the reaction [sodium arsenite results in decreased expression of NFE2L2] CTD PMID:24062023 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO Silybin results in decreased expression of NOS2 protein CTD PMID:16788158 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions EXP Silybin inhibits the reaction [sodium arsenite results in increased expression of NOX4] CTD PMID:24062023 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions		 IEP
ISO		 Silymarin decreases Nqo1 mRNA in liver
Silybin inhibits the reaction [cyfluthrin results in decreased activity of NQO1 protein]		 CTD
RGD		 PMID:31330490 PMID:31432116 RGD:25823187 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 increases expression EXP silymarin increases Nr1h4 mRNA expression in rat kidney and liver RGD PMID:30308196 RGD:15042865 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression ISO Silybin results in increased expression of NR1I2 mRNA CTD PMID:29933105 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions ISO Silybin inhibits the reaction [Acetaldehyde results in decreased expression of OPA1 protein]; Silybin inhibits the reaction [Ethanol results in decreased expression of OPA1 protein] CTD PMID:35158046 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
increases expression		 ISO Silybin results in increased cleavage of PARP1 protein
benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Silybin results in increased cleavage of PARP1 protein]; GDF15 mutant form inhibits the reaction [Silybin results in increased cleavage of PARP1 protein]; pifithrin inhibits the reaction [Silybin results in increased cleavage of PARP1 protein]; Silybin inhibits the reaction [Acetaldehyde results in increased cleavage of PARP1 protein]; Silybin inhibits the reaction [Ethanol results in increased cleavage of PARP1 protein]; Silybin inhibits the reaction [Staurosporine promotes the reaction [Acetaldehyde results in increased cleavage of PARP1 protein]]; Silybin results in increased cleavage of and results in increased activity of PARP1 protein
Silybin results in increased expression of PARP1 protein		 CTD PMID:16777994 PMID:24440808 PMID:27402681 PMID:35158046 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO Silybin results in decreased expression of PCNA protein CTD PMID:16788158 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pf4 platelet factor 4 multiple interactions ISO Silybin inhibits the reaction [Adenosine Diphosphate results in increased secretion of PF4 protein] CTD PMID:29439388 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions ISO Silybin inhibits the reaction [Acetaldehyde results in decreased expression of PINK1 mRNA]; Silybin inhibits the reaction [Acetaldehyde results in decreased expression of PINK1 protein]; Silybin inhibits the reaction [Ethanol results in decreased expression of PINK1 mRNA]; Silybin inhibits the reaction [Ethanol results in decreased expression of PINK1 protein] CTD PMID:35595033 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Plau plasminogen activator, urokinase multiple interactions
decreases expression		 ISO [Silybin co-treated with Arsenic Trioxide] results in decreased expression of PLAU mRNA; Arsenic Trioxide promotes the reaction [Silybin results in decreased expression of PLAU mRNA]; Silybin promotes the reaction [Arsenic Trioxide results in decreased expression of PLAU mRNA] CTD PMID:21969006 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions EXP Silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of POR mRNA] CTD PMID:28619387 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases expression		 ISO Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein]
Silybin results in increased expression of PPARG protein		 CTD PMID:25559859 PMID:27746612 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions ISO Silybin inhibits the reaction [Acetaldehyde results in decreased expression of PRKN mRNA]; Silybin inhibits the reaction [Acetaldehyde results in decreased expression of PRKN protein]; Silybin inhibits the reaction [Ethanol results in decreased expression of PRKN mRNA]; Silybin inhibits the reaction [Ethanol results in decreased expression of PRKN protein] CTD PMID:35595033 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Silybin results in decreased expression of PTGS2 protein CTD PMID:16788158 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 multiple interactions ISO Silybin binds to and results in decreased activity of PTPN1 protein CTD PMID:30160205 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO Silybin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased phosphorylation of RB1 protein] CTD PMID:25559859 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO Silybin inhibits the reaction [ferric ammonium citrate results in decreased expression of RUNX2 protein] CTD PMID:36087815 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO Silybin inhibits the reaction [ferric ammonium citrate results in decreased expression of SIRT1 protein] CTD PMID:36087815 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Skp2 S-phase kinase associated protein 2 decreases expression ISO Silybin results in decreased expression of SKP2 protein CTD PMID:18435416 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338 		JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO Silybin inhibits the reaction [SLC16A1 protein results in increased uptake of Benzoic Acid] CTD PMID:17976262 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions ISO Silybin inhibits the reaction [INS1 protein affects the localization of SLC2A4 protein] CTD PMID:18591783 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO
EXP		 Silybin inhibits the reaction [ferric ammonium citrate results in decreased expression of SOD2 protein] CTD PMID:36087815 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions
decreases response to substance		 ISO fatostatin promotes the reaction [Silybin results in decreased cleavage of SREBF1 protein]; Silybin results in decreased cleavage of and results in increased phosphorylation of SREBF1 protein
SREBF1 protein results in decreased susceptibility to Silybin		 CTD PMID:25294820 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Tfrc transferrin receptor multiple interactions ISO Silybin inhibits the reaction [Acetaldehyde results in increased expression of TFRC protein]; Silybin inhibits the reaction [Ethanol results in increased expression of TFRC protein] CTD PMID:35595033 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP [Silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of TGFB1 mRNA] CTD PMID:16169303 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP [Silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA] CTD PMID:16169303 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO		 Silybin inhibits the reaction [[Isoniazid co-treated with Zidovudine] results in increased expression of TNF protein]
Silybin inhibits the reaction [IL1B protein results in increased expression of TNF mRNA]; Silybin inhibits the reaction [IL1B protein results in increased secretion of TNF protein]		 CTD PMID:28619387 PMID:28914761 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
affects localization
increases phosphorylation
increases expression		 ISO Caffeine inhibits the reaction [Silybin results in increased phosphorylation of TP53 protein]; pifithrin inhibits the reaction [Silybin results in increased phosphorylation of TP53 protein]; Silybin inhibits the reaction [Mitomycin results in increased expression of TP53]
Silybin affects the localization of TP53 protein
Silybin results in increased expression of TP53 protein		 CTD PMID:16777994 PMID:19834285 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 decreases activity
multiple interactions		 EXP
ISO		 Silybin metabolite results in decreased activity of UGT1A1 protein
Silybin inhibits the reaction [UGT1A1 protein results in increased glucuronidation of 7-hydroxy-4-trifluoromethylcoumarin]		 CTD PMID:15155549 PMID:15921999 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 decreases activity
multiple interactions		 EXP
ISO		 Silybin metabolite results in decreased activity of UGT1A6 protein
Silybin inhibits the reaction [UGT1A6 protein results in increased glucuronidation of 7-hydroxy-4-trifluoromethylcoumarin]		 CTD PMID:15155549 PMID:15921999 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 multiple interactions ISO Silybin inhibits the reaction [UGT1A9 protein results in increased glucuronidation of 7-hydroxy-4-trifluoromethylcoumarin] CTD PMID:15155549 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 multiple interactions ISO Silybin inhibits the reaction [UGT2B7 protein results in increased glucuronidation of 7-hydroxy-4-trifluoromethylcoumarin] CTD PMID:15155549 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604 		JBrowse link
G Vasp vasodilator-stimulated phosphoprotein increases phosphorylation ISO Silybin results in increased phosphorylation of VASP protein CTD PMID:29439388 NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
decreases expression		 ISO Silybin promotes the reaction [Lipids deficiency inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]]; Silybin promotes the reaction [Lipids deficiency results in decreased expression of VEGFA protein]
Silybin results in decreased expression of VEGFA protein
Silybin inhibits the reaction [Urethane results in increased secretion of VEGFA protein]		 CTD PMID:16788158 PMID:26087400 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vim vimentin multiple interactions ISO [Silybin co-treated with Arsenic] results in decreased expression of VIM CTD PMID:25868784 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
silychristin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO silychristin results in increased expression of ABCA1 protein CTD PMID:26729088 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Car1 carbonic anhydrase 1 decreases activity ISO silychristin results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208 		JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO silychristin results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Ifng interferon gamma multiple interactions ISO silychristin inhibits the reaction [IL1B protein results in increased expression of IFNG mRNA]; silychristin inhibits the reaction [IL1B protein results in increased secretion of IFNG protein] CTD PMID:28914761 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO silychristin inhibits the reaction [IL1B protein results in increased expression of IFNG mRNA]; silychristin inhibits the reaction [IL1B protein results in increased expression of TNF mRNA]; silychristin inhibits the reaction [IL1B protein results in increased secretion of IFNG protein]; silychristin inhibits the reaction [IL1B protein results in increased secretion of IL2 protein]; silychristin inhibits the reaction [IL1B protein results in increased secretion of TNF protein] CTD PMID:28914761 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO silychristin inhibits the reaction [IL1B protein results in increased secretion of IL2 protein] CTD PMID:28914761 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Pf4 platelet factor 4 multiple interactions ISO silychristin inhibits the reaction [Adenosine Diphosphate results in increased secretion of PF4 protein] CTD PMID:29439388 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO silychristin inhibits the reaction [IL1B protein results in increased expression of TNF mRNA]; silychristin inhibits the reaction [IL1B protein results in increased secretion of TNF protein] CTD PMID:28914761 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Vasp vasodilator-stimulated phosphoprotein increases phosphorylation ISO silychristin results in increased phosphorylation of VASP protein CTD PMID:29439388 NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061 		JBrowse link
taiwanin C term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation		 ISO taiwanin C inhibits the reaction [Dinoprostone results in increased phosphorylation of AKT1 protein]
taiwanin C results in decreased phosphorylation of AKT1 protein		 CTD PMID:30884126 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Bad BCL2-associated agonist of cell death decreases phosphorylation ISO taiwanin C results in decreased phosphorylation of BAD protein CTD PMID:30884126 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO taiwanin C results in increased expression of BAK1 protein CTD PMID:30884126 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO taiwanin C results in decreased expression of BCL2 protein CTD PMID:30884126 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases cleavage ISO taiwanin C results in increased cleavage of CASP3 protein CTD PMID:30884126 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO taiwanin C results in decreased expression of CCNA2 protein CTD PMID:30884126 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions		 ISO taiwanin C results in decreased expression of CCND1 protein
taiwanin C inhibits the reaction [Dinoprostone results in increased expression of CCND1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in decreased expression of CCND1 protein]		 CTD PMID:26537528 PMID:30884126 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO taiwanin C results in decreased expression of CCNE1 protein CTD PMID:30884126 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO taiwanin C results in increased expression of CDKN1A protein CTD PMID:30884126 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases expression		 ISO Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in increased expression of CDKN1B protein] CTD PMID:26537528 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Ctnnb1 catenin beta 1 decreases expression ISO taiwanin C decreases expression of CTNNB1 protein in Chondrocyte Cells RGD PMID:27648737 RGD:153305910 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Egfr epidermal growth factor receptor decreases phosphorylation ISO taiwanin C results in decreased phosphorylation of EGFR protein CTD PMID:26537528 PMID:30884126 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Hdac1 histone deacetylase 1 decreases expression ISO taiwanin C decreases expression of HDAC1 protein in Chondrocyte Cells RGD PMID:27648737 RGD:153305910 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation		 ISO Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in decreased phosphorylation of MAPK1 protein] CTD PMID:26537528 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation		 ISO Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in decreased phosphorylation of MAPK3 protein] CTD PMID:26537528 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO taiwanin C decreases expression of MYC protein in Chondrocyte Cells RGD PMID:27648737 RGD:153305910 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions		 ISO taiwanin C results in decreased expression of PTGS2 protein
Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in decreased expression of PTGS2 protein]		 CTD PMID:26537528 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Tbx3 T-box transcription factor 3 decreases expression ISO taiwanin C decreases expression of TBX3 protein in Chondrocyte Cells RGD PMID:27648737 RGD:153305910 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708 		JBrowse link
teniposide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 decreases response to substance ISO ABCC1 results in decreased susceptibility to Teniposide CTD PMID:8968083 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Ar androgen receptor multiple interactions ISO Teniposide binds to and results in decreased activity of AR protein CTD PMID:25752796 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Teniposide results in increased expression of CDKN1A mRNA; Teniposide results in increased expression of CDKN1A protein CTD PMID:25914138 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases methylation
multiple interactions		 ISO CYP3A4 protein results in decreased methylation of Teniposide
Cyclosporine inhibits the reaction [CYP3A4 protein results in decreased methylation of Teniposide]; Dexamethasone inhibits the reaction [CYP3A4 protein results in decreased methylation of Teniposide]; Erythromycin inhibits the reaction [CYP3A4 protein results in decreased methylation of Teniposide]; Midazolam inhibits the reaction [CYP3A4 protein results in decreased methylation of Teniposide]		 CTD PMID:8114683 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases methylation ISO CYP3A5 protein results in decreased methylation of Teniposide CTD PMID:8114683 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Teniposide binds to and results in decreased activity of ESR1 protein CTD PMID:25752796 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO Teniposide binds to and results in decreased activity of ESR2 protein CTD PMID:25752796 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fgf2 fibroblast growth factor 2 decreases response to substance ISO FGF2 protein results in decreased susceptibility to Teniposide CTD PMID:20221717 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Teniposide inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Mir135b microRNA 135b decreases response to substance ISO MIR135B mRNA results in decreased susceptibility to Teniposide CTD PMID:27570640 NCBI chr13:43,638,857...43,638,953
Ensembl chr13:43,638,857...43,638,953 		JBrowse link
G Mir196b microRNA 196b decreases response to substance ISO MIR196B mRNA results in decreased susceptibility to Teniposide CTD PMID:27570640 NCBI chr 4:81,330,487...81,330,571
Ensembl chr 4:81,330,487...81,330,571 		JBrowse link
G Mttp microsomal triglyceride transfer protein decreases expression
multiple interactions		 ISO Teniposide results in decreased expression of MTTP mRNA
Teniposide promotes the reaction [CETP protein results in decreased expression of MTTP mRNA]		 CTD PMID:25914138 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Teniposide results in decreased expression of MYC mRNA; Teniposide results in decreased expression of MYC protein CTD PMID:11585056 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 multiple interactions
affects localization
affects response to substance		 ISO NR1H2 mutant form inhibits the reaction [Teniposide results in increased expression of CETP mRNA]; Teniposide promotes the reaction [NR1H2 protein results in increased expression of CETP mRNA]
Teniposide affects the localization of NR1H2 protein
NR1H2 protein affects the susceptibility to Teniposide		 CTD PMID:25914138 NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions
increases expression
affects response to substance		 ISO NR1H3 mutant form inhibits the reaction [Teniposide results in increased expression of CETP mRNA]; Teniposide promotes the reaction [NR1H3 protein results in increased expression of CETP mRNA]; Teniposide results in increased expression of and affects the localization of NR1H3 protein
Teniposide results in increased expression of NR1H3 mRNA
NR1H3 protein affects the susceptibility to Teniposide		 CTD PMID:25914138 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Nrip1 nuclear receptor interacting protein 1 decreases expression ISO Teniposide results in decreased expression of NRIP1 mRNA; Teniposide results in decreased expression of NRIP1 protein CTD PMID:25914138 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761 		JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression ISO Teniposide results in decreased expression of ODC1 protein CTD PMID:11585056 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO Teniposide binds to and results in decreased activity of PGR protein CTD PMID:25752796 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO Teniposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]; Tretinoin promotes the reaction [Teniposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]] CTD PMID:25914138 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions ISO Teniposide inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue] CTD PMID:30863990 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO Teniposide binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO Teniposide binds to and results in decreased activity of THRB protein CTD PMID:25752796 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions ISO TOP2A results in decreased susceptibility to [Cisplatin co-treated with Teniposide] CTD PMID:11325482 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
terameprocol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases expression		 ISO terameprocol inhibits the reaction [Doxorubicin results in increased expression of ABCB1 mRNA]; terameprocol inhibits the reaction [SP1 protein results in increased expression of ABCB1 mRNA]
terameprocol results in decreased expression of ABCB1 mRNA		 CTD PMID:16544145 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO terameprocol results in decreased expression of BIRC5 mRNA; terameprocol results in decreased expression of BIRC5 protein CTD PMID:15958646 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO terameprocol inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to CCL2 promoter]]; terameprocol inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; terameprocol inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein] CTD PMID:19133137 PMID:21138578 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO terameprocol affects the reaction [Lipopolysaccharides results in increased expression of CCL3 protein] CTD PMID:19133137 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO terameprocol inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to CCL5 promoter]] CTD PMID:21138578 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO terameprocol results in decreased expression of CDK1 mRNA; terameprocol results in decreased expression of CDK1 protein CTD PMID:15958646 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions ISO terameprocol promotes the reaction [Lipopolysaccharides results in increased expression of CSF1 protein] CTD PMID:19133137 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO terameprocol inhibits the reaction [Lipopolysaccharides results in increased expression of CSF2 protein] CTD PMID:19133137 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Csf3 colony stimulating factor 3 multiple interactions ISO terameprocol inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein] CTD PMID:19133137 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO terameprocol affects the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:19133137 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO terameprocol affects the reaction [Lipopolysaccharides results in increased expression of IL1A protein] CTD PMID:19133137 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO terameprocol affects the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:19133137 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO terameprocol affects the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; terameprocol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:19133137 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO terameprocol inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to CCL2 promoter]]; terameprocol inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to CCL5 promoter]]; terameprocol inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to TNF promoter]] CTD PMID:21138578 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Sp1 Sp1 transcription factor decreases activity
multiple interactions		 ISO terameprocol results in decreased activity of SP1 protein
terameprocol inhibits the reaction [SP1 protein results in increased expression of ABCB1 mRNA]		 CTD PMID:16544145 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO terameprocol inhibits the reaction [Lipopolysaccharides results in increased expression of TIMP1 protein] CTD PMID:19133137 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO terameprocol inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to TNF promoter]]; terameprocol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; terameprocol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:19133137 PMID:21138578 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B multiple interactions ISO terameprocol inhibits the reaction [Lipopolysaccharides results in increased expression of TNFRSF1B protein] CTD PMID:19133137 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
Trachelogenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma multiple interactions ISO trachelogenin inhibits the reaction [IFNG results in increased expression of STAT1 protein] CTD PMID:25100250 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO trachelogenin inhibits the reaction [IL6 results in increased expression of STAT3 protein] CTD PMID:25100250 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO trachelogenin inhibits the reaction [IFNG results in increased expression of STAT1 protein] CTD PMID:25100250 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO trachelogenin inhibits the reaction [IL6 results in increased expression of STAT3 protein] CTD PMID:25100250 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19834
    chemical entity 19832
      group 19791
        polyatomic entity 19790
          molecule 19695
            cyclic compound 19511
              organic cyclic compound 19493
                organic aromatic compound 19360
                  phenylpropanoid 11289
                    lignan 1703
                      (+)-(7'S,8S,8'S)-3',4,4'-trihydroxy-5,5'-dimethoxy-2,7'-cyclolignan 0
                      (+)-(7'S,8S,8'S)-3',4,4'-trihydroxy-5-methoxy-2,7'-cyclolignan 0
                      (+)-(7'S,8S,8'S)-3',4-dihydroxy-2',3,4',5-tetramethoxy-6',9-epoxy-2,7'-cyclolignan-9'-ol 0
                      (+)-(7R,7'R,8S,8'S)-4'-hydroxy-3,3',4,5,5'-pentamethoxy-7,7'-epoxylignan-9,9'-diol 0
                      (+)-(7S,8R,8'R)-5,5'-dimethoxylariciresinol 0
                      (+)-(7S,8S)-1',4-dihydroxy-3,3',5'-trimethoxy-7',8',9'-trinor-8,4'-oxyneolignan-7,9-diol 0
                      (+)-(8R,8'R)-3',4,4'-trihydroxy-3-methoxylignan 0
                      (+)-(8R,8'R)-4-hydroxy-5-methoxy-1',2',3',4',5',6'-hexanor-2,7'-cyclolignan-7'-one 0
                      (+)-(8S,8'R)-3',4,4'-trihydroxy-5,5'-dimethoxylignan 0
                      (+)-(8S,8'R)-4,4'-dihydroxy-3,3',5'-trimethoxylignan 0
                      (+)-(8S,8'R)-4,4'-dihydroxy-3-methoxylignan 0
                      (+)-(8S,8'R)-4-hydroxy-3,3',4',5'-tetramethoxylignan 0
                      (+)-(8S,8'R)-4-hydroxy-5-methoxy-1',2',3',4',5',6'-hexanor-2,7'-cyclolignan-7'-one 0
                      (+)-(8S,8'R)-9'-acetoxy-4,4'-dihydroxy-3,3',5'-trimethoxylignan 0
                      (+)-(8S,8'R)-9-acetoxy-4,4'-dihydroxy-3,3',5'-trimethoxylignan 0
                      (+)-3'-hydroxylarreatricin 0
                      (+)-5'-methoxylariciresinol 0
                      (+)-7-epi-Syringaresinol 4'-glucoside 0
                      (+)-DCA-CC 0
                      (+)-DCA-CL 0
                      (+)-Eudesmin 2
                      (+)-Fargesin 0
                      (+)-Galbacin 0
                      (+)-Ligballinol 0
                      (+)-Lyoniresinol 9-glucoside 0
                      (+)-Pinoresinol 4-O-glucoside 0
                      (+)-guaiacin 0
                      (+)-isolariciresinol 6
                      (+)-lariciresinol + 9
                      (+)-larreatricin 0
                      (+)-lyoniresinol + 0
                      (+)-lyoniresinol 4,4'-bis-O-beta-D-glucopyranoside 0
                      (+)-lyoniresinol-3-alpha-O-beta-D-glucopyranoside 0
                      (+)-sesamin + 17
                      (+)-sesamin dicatechol 0
                      (+)-sesamin monocatechol + 0
                      (-)-(7'R,8R,8'R)-4,4'-dihydroxy-3,3',5-trimethoxy-2,7'-cyclolignan 0
                      (-)-(7'S,8S,8'R)-4,4'-dihydroxy-3,3',5,5'-tetramethoxy-7',9-epoxylignan-9'-ol-7-one 0
                      (-)-(7R,7'R,8S,8'S)-4'-hydroxy-3,3',4,5,5'-pentamethoxy-7,9':7',9-diepoxylignane 0
                      (-)-(7R,8R,8'R)-4,4'-dihydroxy-3,3',5'-trimethoxy-7,9'-epoxylignan 0
                      (-)-(7S,7'S,8R,8'R)-4,4'-dihydroxy-3,3',5,5'-tetramethoxy-7,7'-epoxylignan-9,9'-diol 0
                      (-)-(8R,8'S)-3,3',4-trimethoxy-4'-hydroxylignan 0
                      (-)-3,4-dimethoxy-3,4-desmethylenedioxycubebin 0
                      (-)-5'-desmethylyatein 0
                      (-)-5'-methoxyisolariciresinol 0
                      (-)-8'-epi-aristoligone 0
                      (-)-Arctigenin 37
                      (-)-DCA-CC 0
                      (-)-DCA-CL 0
                      (-)-Matairesinol 4'-[apiosyl-(1->2)-glucoside] 0
                      (-)-Pinoresinol glucoside 0
                      (-)-Syringaresnol-4-O-beta-D-apiofuranosyl-(1->2)-beta-D-glucopyranoside 0
                      (-)-bursehernin + 1
                      (-)-cubebin 0
                      (-)-demethoxylpinoresinol 0
                      (-)-isoguaiacin 0
                      (-)-lariciresinol 9
                      (-)-larreatricin 0
                      (-)-matairesinol + 30
                      (-)-medioresinol 0
                      (-)-pluviatolide + 1
                      (-)-sanguinolignan A 0
                      (-)-sanguinolignan B 0
                      (-)-sanguinolignan C 0
                      (-)-sanguinolignan D 0
                      (2R,3R)-3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)-2-\{4-[(1E)-3-hydroxyprop-1-en-1-yl]-2-methoxyphenoxy\}propyl beta-D-glucopyranoside 0
                      (2R,3S,4R)-3a-[(beta-D-glucopyranosyl)oxy]lyoniresinol 0
                      (2R,3S,4S)-3a-[(beta-D-glucopyranosyl)oxy]lyoniresinol 0
                      (2S,3R,4R)-3a-[(beta-D-glucopyranosyl)oxy]lyoniresinol 0
                      (2S,3R,4S)-3a-[(beta-D-glucopyranosyl)oxy]lyoniresinol 0
                      (2S,3S)-(+)-1,4-Dimethoxy-2,3-diveratrylbutane 0
                      (3S)-5-[(3S)-10-hydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-10-ol 0
                      (3S,3'S,4S,4'S)-3,3'-Dimethyl-7,7',9,9'-tetramethoxy-3,3',4,4'-tetrahydro-5,6'-bi(1H-naphtho[2,3-c]pyran)-4,4',10,10'-tetrol 0
                      (3S,3'S,4S,4'S,5R)-10,10'-dihydroxy-7,7',9,9'-tetramethoxy-3,3'-dimethyl-3,3',4,4'-tetrahydro-1H,1'H-5,5'-bibenzo[g]isochromene-4,4'-diyl diacetate 0
                      (3S,3'S,4S,4'S,6'S)-10,10'-dihydroxy-7,7',9,9'-tetramethoxy-3,3'-dimethyl-3,3',4,4'-tetrahydro-1H,1'H-5,6'-bibenzo[g]isochromene-4,4'-diyl diacetate 0
                      (3S,4S)-5-[(3S)-10-hydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene-4,10-diol 0
                      (3S,4S)-6-[(3S)-10-hydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene-4,10-diol 0
                      (3S,4S)-6-[(3S,4S)-4,10-dihydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-9-methoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene-4,7,10-triol 0
                      (3S,4S)-7-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxy-5-[(3S,4S)-7-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxy-4,10-dihydroxy-9-methoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-9-methoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene-4,10-diol 0
                      (7'R)-(+)-Lyoniresinol 9'-glucoside 0
                      (7'S)-parabenzlactone 0
                      (7R)-7-hydroxylariciresinol 0
                      (7R)-7-hydroxytaxiresinol 0
                      (7R*,8R*)-3-Methoxy-3',4,7,9,9'-pentahydroxy-8,4'-oxyneolignan 4-xyloside 0
                      (8R,8'R,9S)-9-Hydroxy-3,4-dimethoxy-3',4'-methylenoxy-9,9'-epoxylignan 0
                      (8S,8'S)-Secoisolariciresinol 9-xyloside 0
                      1,2,3,4-tetra phenylbutane-2,3-diol 0
                      1-Acetoxypinoresinol 0
                      2'-Hydroxyenterolactone 0
                      2,3-Bis(3-hydroxybenzyl)butane-1,4-diol 3
                      2,5-bis(4-hydroxy-3-methoxyphenyl)-3,4-dimethyloxolan-3-ol 0
                      2-(3-Methoxy-4-hydroxyphenyl)-5-(3,4-dimethoxyphenyl)-3,4-dimethyltetrahydrofuran 0
                      2-(4-hydroxy-3,5-dimethoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-7H-pyrano[2,3-g][1,4]benzodioxin-7-one 0
                      2-Hydroxyenterodiol 0
                      2-Hydroxyenterolactone 0
                      2-[4-[(3r,3ar,6s,6ar)-3-(3,4-dimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-2-methoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol 0
                      2-[[(3S)-5-[(3S)-7-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxy-10-hydroxy-9-methoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-10-hydroxy-9-methoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-7-yl]oxy]-6-(hydroxymethyl)-5-methoxyoxane-3,4-diol 0
                      3,6-Bis(3,4,5-trimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan 0
                      3-Methyl-2-butenyl-(-)-piperitol 0
                      3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one 0
                      4'-Hydroxyenterolactone 0
                      4'-demethyldeoxypodophyllotoxin 0
                      4-(7-Hydroxy-6-methoxy-2,3-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)benzene-1,2-diol 0
                      4-Hydroxy-9-(4-hydroxy-3,5-dimethoxy-phenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[6,5-f][1,3]benzodioxol-8-one 0
                      4-Hydroxyenterodiol 0
                      4-Hydroxyenterolactone 0
                      4-[(1S,3aR,4S,6aR)-4-(1,3-benzodioxol-5-yl)tetrahydrofuro[3,4-c]furan-1-yl]-2-methoxyphenol 0
                      4-[(1s,3as,4r,6ar)-3a-hydroxy-4-(4-hydroxy-3-methoxyphenyl)tetrahydro-1h,3h-furo[3,4-c]furan-1-yl]-2-methoxyphenyl beta-d-glucopyranoside 0
                      4-[(2R,3R)-4-(4-hydroxy-3-methoxyphenyl)-2,3-bis(hydroxymethyl)butyl]-2-methoxyphenyl beta-D-glucopyranoside 0
                      4-[(2S,3R)-4-(1,3-benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxyphenol 0
                      4-[3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one 0
                      4-[4-(4-hydroxy-3-methoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl hexopyranoside 0
                      4-\{(1S,3aR,4S,6aR)-4-[4-(hexopyranosyloxy)-3-methoxyphenyl]tetrahydro-1H,3H-furo[3,4-c]furan-1-yl\}-2-methoxyphenyl hexopyranoside 0
                      4-\{[(3s,4r,5s)-3-hydroxy-5-(4-hydroxy-3-methoxyphenyl)-4-(hydroxymethyl)tetrahydro-3-furanyl]methyl\}-2-methoxyphenyl beta-d-glucopyranoside 0
                      4-epi-julichrome Q10.10B 0
                      4-epi-julichrome Q10.10C 0
                      4-hydroxy-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]butyl hexopyranoside 0
                      4-hydroxysesamin 0
                      4-methoxymagnaldehyde B 0
                      4alpha-hydroxypinoresinol 0
                      4beta-[(beta-D-glucopyranosyl)hydroxy]-pinoresinol 0
                      5'-Demethoxydeoxypodophyllotoxin 0
                      5,5'-Bis(\{3-[(2H-1,3-benzodioxol-5-yl)methyl]-2-methylbutyl\})-3,3'-dimethoxy-[1,1'-biphenyl]-2,2'-diol 0
                      5-(3,4-Dihydroxyphenyl)-6,7-dimethyl-5,6,7,8-tetrahydronaphthalene-2,3-diol 0
                      5-Hydroxyenterolactone 0
                      5-Methoxygalbelgin 0
                      5-Methoxyhinokinin 0
                      5-[(6-\{2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]-4-\{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy\}butoxy\}-3,4,5-trihydroxyoxan-2-yl)methoxy]-3-hydroxy-3-methyl-5-oxopentanoic acid 0
                      5-\{4-[4-(hexopyranosyloxy)-3,5-dimethoxyphenyl]tetrahydro-1H,3H-furo[3,4-c]furan-1-yl\}-2-methoxyphenyl hexopyranoside 0
                      6'-Hydroxyenterolactone 0
                      6'-O-desmethyl ES-242-4 0
                      6-(\{8,11-dihydroxy-17-methoxy-10-oxo-2-oxatricyclo[13.2.2.1?,?]icosa-1(17),3,5,7(20),15,18-hexaen-4-yl\}oxy)-3,4,5-trihydroxyoxane-2-carboxylic acid 0
                      6-Hydroxyenterodiol 0
                      6-Hydroxyenterolactone 0
                      6′-O-desmethyl ES-242-2 0
                      7-Hydroxyaustrobailignan 5 0
                      7-Hydroxyenterolactone 0
                      7-hydroxysecoisolariciresinol 0
                      8'-Episesaminone 0
                      8-Acetoxy-4'-methoxypinoresinol 0
                      8-Acetoxy-4'-methoxypinoresinol 4-glucoside 0
                      8-Acetoxypinoresinol 0
                      8-Acetoxypinoresinol 4-glucoside 0
                      8-Hydroxy-4'-methoxypinoresinol 0
                      8-Hydroxypinoresinol 0
                      8-Hydroxypinoresinol 4-glucoside 0
                      8-Hydroxypinoresinol 8-glucoside 0
                      A 39183A 0
                      Anhydropseudophlegmacin-9,10-quinone-3'-amino-8'-O-methyl ether 0
                      Antibiotic ES 242-5 0
                      Arctiin 13
                      Aschantin 0
                      Austrobailignan 1 0
                      Austrobailignan 7 0
                      Austrocolorin A1 0
                      Austrocolorone B 0
                      Biondinin B 0
                      Bioxanthracene 7 0
                      Carinol 0
                      Carissanol 0
                      Caruilignan D 0
                      Citrusin A 0
                      Citrusin B 0
                      Cleistanone(rac) 0
                      Clemaphenol A 0
                      Clusin 0
                      Conoideocrellone A 0
                      Conoideocrellone B 0
                      Crisamicin A 0
                      Crisamicin C 0
                      Cubebinin 0
                      Cubebininolide 0
                      Cubebinone 0
                      Cycloolivil 0
                      Dalpanin 0
                      Dehydrodiferulic dilactone 0
                      Dihydroclusin 0
                      Dihydrocubebin, rel- 0
                      Diphyllin 0
                      Divanillyltetrahydrofuran ferulate 0
                      Dongtinganthracene A 0
                      Dongtinganthracene B 0
                      Dongtinganthracene C 0
                      Dongtinganthracene D 0
                      ES 242-1 0
                      ES-242-1 0
                      ES-242-2 0
                      ES-242-3 0
                      ES-242-4 0
                      ES-242-6 0
                      ES-242-7 0
                      ES-242-8 0
                      Eleutheroside E 0
                      Enterodiol 0
                      Enterolactone 965
                      Eucommin A 0
                      Fargesin 8
                      Forsythin 0
                      Fragransin B2 0
                      Fragransin C1 0
                      Fragransin D1 0
                      Fragransin D3 0
                      G b S r S acetate 0
                      G b S r S b G acetate 0
                      G(8-O-4)G' 0
                      G(8-O-4)G(8-O-4)S(8-5)G' 0
                      G(8-O-4)G(8-O-4)S(8-8)S 0
                      G(8-O-4)S(8-8)S(8-O-4)G 0
                      G(8-O-4)S(8-O-4)S(8-5)G 0
                      G(8–O–4)S(8–O–4)S(8–8)S 0
                      G(8–O–4)SP(8–8)S 0
                      G-8-O-4 -S 0
                      GTRI-BB 0
                      Ganschisandrin 0
                      Gmelinol 0
                      Grandisin 0
                      Hemiariensin 0
                      Heterotropan 0
                      Hirtusneanoside 0
                      Isolariciresinol 4'-O-beta-D-glucoside 0
                      Isolariciresinol 9'-O-alpha-L-arabinofuranoside 0
                      Isolariciresinol 9'-O-beta-D-glucoside 0
                      Isolariciresinol 9-O-beta-D-glucoside 0
                      Isoyatein 0
                      Justicidin A 0
                      Justicidin B 0
                      Justicidin D 0
                      Karwinskione 0
                      LSM-20517 0
                      LSM-34734 0
                      LSM-4504 0
                      Labadoside 0
                      Lappaol C 0
                      Lappaol D 0
                      Lariciresinol 4-o-glucoside 0
                      Ligraminol A 0
                      Ligraminol B 0
                      Lugdunomycin 0
                      Lyoniresinol 9'-sulfate 0
                      Maculalactone L 0
                      Magnosalicin 0
                      Magnosalin 0
                      Malabaricano 0
                      Myricatomentoside I 0
                      Neoarctin A 0
                      Neoarctin B 0
                      Neocuscutoside C 0
                      Neoisostegane 0
                      Nordihydroguaiaretate 0
                      Nortrachelogenin 0
                      O-Ethylcubebin 0
                      Otobain 0
                      Otobanone 0
                      Phyllanthin 4
                      Phyllanthostatin A 0
                      Pinoresinol biphenyl 0
                      Pinoresinol biphenyl acetate 0
                      Pinoresinol diacetate 0
                      Pinoresinol diglucoside 0
                      Plicatic acid 0
                      Podophyllotoxone 0
                      Prostalidin A 0
                      Prupaside 0
                      Ramontoside 0
                      Rufoolivacin B 0
                      Rufoolivacin D 0
                      Rufoschweinitzin 0
                      S b S r S 0
                      S b S r S acetate 0
                      SP(8-8)S 0
                      Sanshodiol 0
                      Saucernetin 0
                      Secoisolariciresinol 9,9'-diglucoside 0
                      Sesaminol glucoside 0
                      Sesaminol glucosyl-(1->2)-glucoside 0
                      Sesaminone 0
                      Sesartemin 0
                      Setomimycin 0
                      Simplexoside 0
                      Sinapicolone 0
                      Sinapiquinone 0
                      Spirodalesol 0
                      Ssioriside 0
                      Steganacin 0
                      Trachelogenin 4
                      Tracheloside 0
                      Veraguensin 0
                      Xanthoxylol 0
                      Yangambin 0
                      [(3S,4S)-5-[(3S)-7-[(2S,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxy-10-hydroxy-9-methoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-10-hydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-4-yl] acetate 0
                      [(3S,4S)-5-[(3S,4S)-4,10-dihydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-10-hydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-4-yl] acetate 0
                      [(3S,4S)-6-[(3S)-7-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxy-10-hydroxy-9-methoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-10-hydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-4-yl] acetate 0
                      [(3S,4S)-6-[(3S,4S)-4-acetyloxy-10-hydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-7,10-dihydroxy-9-methoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-4-yl] acetate 0
                      [4-(4-hydroxy-3-methoxybenzyl)-2-(4-hydroxy-3-methoxyphenyl)tetrahydro-3-furanyl]methyl hexopyranoside 0
                      aiphanol 0
                      alpha-Conidendrin 0
                      alpha-peltatin + 0
                      ananolignan B 0
                      ananolignan C 0
                      ananolignan D 0
                      ananolignan E 0
                      ananolignan F 0
                      ananolignan G 0
                      ananolignan H 0
                      ananolignan I 0
                      ananolignan J 0
                      ananolignan K 0
                      ananolignan L 0
                      ananolignan M 0
                      ananolignan N 0
                      anolignan A 0
                      anolignan B 0
                      beilschminol A, rel- 0
                      beta-D-Glucopyranoside, 2-methoxy-4-[(1S,2S,3S)-1,2,3,4-tetrahydro-3,7-dihydroxy-2,3-bis(hydroxymethyl)-6-methoxy-1-naphthalenyl]phenyl 0
                      beta-Peltatin A methyl ether 0
                      beta-peltatin 0
                      brugunin A 0
                      buddlenol A 0
                      buddlenol E 0
                      burseran 0
                      cleistanthins + 0
                      cyclolignane 0
                      dehydrodiconiferyl dibenzoate 0
                      demethoxyaschantin 0
                      deoxypodophyllotoxin 6
                      dihydroanhydropodorhizol 0
                      dihydrocubebin 0
                      enterolactone 3'-sulfate 0
                      flavonolignan + 140
                      futokadsurin A 0
                      futokadsurin B 0
                      futokadsurin C 0
                      galgravin 0
                      graminone B 0
                      helioxanthin 5
                      hinokinin 0
                      interiotherin A 0
                      interiotherin B 0
                      interiotherin C 0
                      isotaxiresinol 0
                      lignin cw compound-2008 0
                      lignin cw compound-2024 0
                      lignin cw compound-2025 0
                      lignin cw compound-2027 0
                      lignin cw compound-2030 0
                      lignin cw compound-2035 0
                      lignin cw compound-2036 0
                      lignin cw compound-2059 0
                      lignin cw compound-2062 0
                      lignin cw compound-263 0
                      lignin cw compound-3002 0
                      lignin cw compound-3014 0
                      lignin cw compound-3016 0
                      lignin cw compound-3017 0
                      lignin cw compound-3018 0
                      lignin cw compound-3042 0
                      longipedumin A 0
                      manassantin A 0
                      manassantin B 0
                      matairesinoside 0
                      meso-3,3'-didemethoxynectandrin B 0
                      meso-dihydroguaiaretic acid 0
                      mitopodozide 0
                      negundin B 0
                      nordihydroguaiaretic acid + 89
                      picropodophyllotoxin 16
                      pinoresinol + 7
                      podophyllotoxin + 676
                      rel-(+)-(7'S,8S,8'S)-4,4'-dihydroxy-3',5,5'-trimethoxy-2,7'-cyclolignan 0
                      rel-(-)-(7S,7'R,8S,8'R)-4,4'-dihydroxy-3,3',5'-trimethoxy-7,7'-epoxylignan 0
                      rel-(7R,8R,7'R,8'R)-3',4'-methylenedioxy-3,4,5,5'-tetramethoxy-7,7'-epoxylignan 0
                      rel-(7R,8R,7'R,8'R)-3,4,3',4'-dimethylene-dioxy-5,5'-dimethoxy-7,7'-epoxylignan 0
                      rel-(7S,8S,7'R,8'R)-3,3',4,4',5,5'-hexamethoxy-7.O.7',8.8'-lignan 0
                      salicifoliol 0
                      savinin 0
                      secoisolariciresinol + 1
                      styraxin 0
                      syringaresinol + 11
                      syringylresinol diacetate 0
                      taiwanin C 18
                      tanegool 0
                      taxiresinol 0
                      terameprocol 18
                      vladinol D 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19834
    subatomic particle 19832
      composite particle 19832
        hadron 19832
          baryon 19832
            nucleon 19832
              atomic nucleus 19832
                atom 19832
                  main group element atom 19782
                    p-block element atom 19782
                      p-block molecular entity 19782
                        carbon group molecular entity 19731
                          organic molecular entity 19727
                            organic molecule 19680
                              organic cyclic compound 19493
                                organic aromatic compound 19360
                                  phenylpropanoid 11289
                                    lignan 1703
                                      (+)-(7'S,8S,8'S)-3',4,4'-trihydroxy-5,5'-dimethoxy-2,7'-cyclolignan 0
                                      (+)-(7'S,8S,8'S)-3',4,4'-trihydroxy-5-methoxy-2,7'-cyclolignan 0
                                      (+)-(7'S,8S,8'S)-3',4-dihydroxy-2',3,4',5-tetramethoxy-6',9-epoxy-2,7'-cyclolignan-9'-ol 0
                                      (+)-(7R,7'R,8S,8'S)-4'-hydroxy-3,3',4,5,5'-pentamethoxy-7,7'-epoxylignan-9,9'-diol 0
                                      (+)-(7S,8R,8'R)-5,5'-dimethoxylariciresinol 0
                                      (+)-(7S,8S)-1',4-dihydroxy-3,3',5'-trimethoxy-7',8',9'-trinor-8,4'-oxyneolignan-7,9-diol 0
                                      (+)-(8R,8'R)-3',4,4'-trihydroxy-3-methoxylignan 0
                                      (+)-(8R,8'R)-4-hydroxy-5-methoxy-1',2',3',4',5',6'-hexanor-2,7'-cyclolignan-7'-one 0
                                      (+)-(8S,8'R)-3',4,4'-trihydroxy-5,5'-dimethoxylignan 0
                                      (+)-(8S,8'R)-4,4'-dihydroxy-3,3',5'-trimethoxylignan 0
                                      (+)-(8S,8'R)-4,4'-dihydroxy-3-methoxylignan 0
                                      (+)-(8S,8'R)-4-hydroxy-3,3',4',5'-tetramethoxylignan 0
                                      (+)-(8S,8'R)-4-hydroxy-5-methoxy-1',2',3',4',5',6'-hexanor-2,7'-cyclolignan-7'-one 0
                                      (+)-(8S,8'R)-9'-acetoxy-4,4'-dihydroxy-3,3',5'-trimethoxylignan 0
                                      (+)-(8S,8'R)-9-acetoxy-4,4'-dihydroxy-3,3',5'-trimethoxylignan 0
                                      (+)-3'-hydroxylarreatricin 0
                                      (+)-5'-methoxylariciresinol 0
                                      (+)-7-epi-Syringaresinol 4'-glucoside 0
                                      (+)-DCA-CC 0
                                      (+)-DCA-CL 0
                                      (+)-Eudesmin 2
                                      (+)-Fargesin 0
                                      (+)-Galbacin 0
                                      (+)-Ligballinol 0
                                      (+)-Lyoniresinol 9-glucoside 0
                                      (+)-Pinoresinol 4-O-glucoside 0
                                      (+)-guaiacin 0
                                      (+)-isolariciresinol 6
                                      (+)-lariciresinol + 9
                                      (+)-larreatricin 0
                                      (+)-lyoniresinol + 0
                                      (+)-lyoniresinol 4,4'-bis-O-beta-D-glucopyranoside 0
                                      (+)-lyoniresinol-3-alpha-O-beta-D-glucopyranoside 0
                                      (+)-sesamin + 17
                                      (+)-sesamin dicatechol 0
                                      (+)-sesamin monocatechol + 0
                                      (-)-(7'R,8R,8'R)-4,4'-dihydroxy-3,3',5-trimethoxy-2,7'-cyclolignan 0
                                      (-)-(7'S,8S,8'R)-4,4'-dihydroxy-3,3',5,5'-tetramethoxy-7',9-epoxylignan-9'-ol-7-one 0
                                      (-)-(7R,7'R,8S,8'S)-4'-hydroxy-3,3',4,5,5'-pentamethoxy-7,9':7',9-diepoxylignane 0
                                      (-)-(7R,8R,8'R)-4,4'-dihydroxy-3,3',5'-trimethoxy-7,9'-epoxylignan 0
                                      (-)-(7S,7'S,8R,8'R)-4,4'-dihydroxy-3,3',5,5'-tetramethoxy-7,7'-epoxylignan-9,9'-diol 0
                                      (-)-(8R,8'S)-3,3',4-trimethoxy-4'-hydroxylignan 0
                                      (-)-3,4-dimethoxy-3,4-desmethylenedioxycubebin 0
                                      (-)-5'-desmethylyatein 0
                                      (-)-5'-methoxyisolariciresinol 0
                                      (-)-8'-epi-aristoligone 0
                                      (-)-Arctigenin 37
                                      (-)-DCA-CC 0
                                      (-)-DCA-CL 0
                                      (-)-Matairesinol 4'-[apiosyl-(1->2)-glucoside] 0
                                      (-)-Pinoresinol glucoside 0
                                      (-)-Syringaresnol-4-O-beta-D-apiofuranosyl-(1->2)-beta-D-glucopyranoside 0
                                      (-)-bursehernin + 1
                                      (-)-cubebin 0
                                      (-)-demethoxylpinoresinol 0
                                      (-)-isoguaiacin 0
                                      (-)-lariciresinol 9
                                      (-)-larreatricin 0
                                      (-)-matairesinol + 30
                                      (-)-medioresinol 0
                                      (-)-pluviatolide + 1
                                      (-)-sanguinolignan A 0
                                      (-)-sanguinolignan B 0
                                      (-)-sanguinolignan C 0
                                      (-)-sanguinolignan D 0
                                      (2R,3R)-3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)-2-\{4-[(1E)-3-hydroxyprop-1-en-1-yl]-2-methoxyphenoxy\}propyl beta-D-glucopyranoside 0
                                      (2R,3S,4R)-3a-[(beta-D-glucopyranosyl)oxy]lyoniresinol 0
                                      (2R,3S,4S)-3a-[(beta-D-glucopyranosyl)oxy]lyoniresinol 0
                                      (2S,3R,4R)-3a-[(beta-D-glucopyranosyl)oxy]lyoniresinol 0
                                      (2S,3R,4S)-3a-[(beta-D-glucopyranosyl)oxy]lyoniresinol 0
                                      (2S,3S)-(+)-1,4-Dimethoxy-2,3-diveratrylbutane 0
                                      (3S)-5-[(3S)-10-hydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-10-ol 0
                                      (3S,3'S,4S,4'S)-3,3'-Dimethyl-7,7',9,9'-tetramethoxy-3,3',4,4'-tetrahydro-5,6'-bi(1H-naphtho[2,3-c]pyran)-4,4',10,10'-tetrol 0
                                      (3S,3'S,4S,4'S,5R)-10,10'-dihydroxy-7,7',9,9'-tetramethoxy-3,3'-dimethyl-3,3',4,4'-tetrahydro-1H,1'H-5,5'-bibenzo[g]isochromene-4,4'-diyl diacetate 0
                                      (3S,3'S,4S,4'S,6'S)-10,10'-dihydroxy-7,7',9,9'-tetramethoxy-3,3'-dimethyl-3,3',4,4'-tetrahydro-1H,1'H-5,6'-bibenzo[g]isochromene-4,4'-diyl diacetate 0
                                      (3S,4S)-5-[(3S)-10-hydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene-4,10-diol 0
                                      (3S,4S)-6-[(3S)-10-hydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene-4,10-diol 0
                                      (3S,4S)-6-[(3S,4S)-4,10-dihydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-9-methoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene-4,7,10-triol 0
                                      (3S,4S)-7-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxy-5-[(3S,4S)-7-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxy-4,10-dihydroxy-9-methoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-9-methoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene-4,10-diol 0
                                      (7'R)-(+)-Lyoniresinol 9'-glucoside 0
                                      (7'S)-parabenzlactone 0
                                      (7R)-7-hydroxylariciresinol 0
                                      (7R)-7-hydroxytaxiresinol 0
                                      (7R*,8R*)-3-Methoxy-3',4,7,9,9'-pentahydroxy-8,4'-oxyneolignan 4-xyloside 0
                                      (8R,8'R,9S)-9-Hydroxy-3,4-dimethoxy-3',4'-methylenoxy-9,9'-epoxylignan 0
                                      (8S,8'S)-Secoisolariciresinol 9-xyloside 0
                                      1,2,3,4-tetra phenylbutane-2,3-diol 0
                                      1-Acetoxypinoresinol 0
                                      2'-Hydroxyenterolactone 0
                                      2,3-Bis(3-hydroxybenzyl)butane-1,4-diol 3
                                      2,5-bis(4-hydroxy-3-methoxyphenyl)-3,4-dimethyloxolan-3-ol 0
                                      2-(3-Methoxy-4-hydroxyphenyl)-5-(3,4-dimethoxyphenyl)-3,4-dimethyltetrahydrofuran 0
                                      2-(4-hydroxy-3,5-dimethoxyphenyl)-3-(hydroxymethyl)-2,3-dihydro-7H-pyrano[2,3-g][1,4]benzodioxin-7-one 0
                                      2-Hydroxyenterodiol 0
                                      2-Hydroxyenterolactone 0
                                      2-[4-[(3r,3ar,6s,6ar)-3-(3,4-dimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-2-methoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol 0
                                      2-[[(3S)-5-[(3S)-7-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxy-10-hydroxy-9-methoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-10-hydroxy-9-methoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-7-yl]oxy]-6-(hydroxymethyl)-5-methoxyoxane-3,4-diol 0
                                      3,6-Bis(3,4,5-trimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan 0
                                      3-Methyl-2-butenyl-(-)-piperitol 0
                                      3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one 0
                                      4'-Hydroxyenterolactone 0
                                      4'-demethyldeoxypodophyllotoxin 0
                                      4-(7-Hydroxy-6-methoxy-2,3-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)benzene-1,2-diol 0
                                      4-Hydroxy-9-(4-hydroxy-3,5-dimethoxy-phenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[6,5-f][1,3]benzodioxol-8-one 0
                                      4-Hydroxyenterodiol 0
                                      4-Hydroxyenterolactone 0
                                      4-[(1S,3aR,4S,6aR)-4-(1,3-benzodioxol-5-yl)tetrahydrofuro[3,4-c]furan-1-yl]-2-methoxyphenol 0
                                      4-[(1s,3as,4r,6ar)-3a-hydroxy-4-(4-hydroxy-3-methoxyphenyl)tetrahydro-1h,3h-furo[3,4-c]furan-1-yl]-2-methoxyphenyl beta-d-glucopyranoside 0
                                      4-[(2R,3R)-4-(4-hydroxy-3-methoxyphenyl)-2,3-bis(hydroxymethyl)butyl]-2-methoxyphenyl beta-D-glucopyranoside 0
                                      4-[(2S,3R)-4-(1,3-benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxyphenol 0
                                      4-[3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one 0
                                      4-[4-(4-hydroxy-3-methoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenyl hexopyranoside 0
                                      4-\{(1S,3aR,4S,6aR)-4-[4-(hexopyranosyloxy)-3-methoxyphenyl]tetrahydro-1H,3H-furo[3,4-c]furan-1-yl\}-2-methoxyphenyl hexopyranoside 0
                                      4-\{[(3s,4r,5s)-3-hydroxy-5-(4-hydroxy-3-methoxyphenyl)-4-(hydroxymethyl)tetrahydro-3-furanyl]methyl\}-2-methoxyphenyl beta-d-glucopyranoside 0
                                      4-epi-julichrome Q10.10B 0
                                      4-epi-julichrome Q10.10C 0
                                      4-hydroxy-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]butyl hexopyranoside 0
                                      4-hydroxysesamin 0
                                      4-methoxymagnaldehyde B 0
                                      4alpha-hydroxypinoresinol 0
                                      4beta-[(beta-D-glucopyranosyl)hydroxy]-pinoresinol 0
                                      5'-Demethoxydeoxypodophyllotoxin 0
                                      5,5'-Bis(\{3-[(2H-1,3-benzodioxol-5-yl)methyl]-2-methylbutyl\})-3,3'-dimethoxy-[1,1'-biphenyl]-2,2'-diol 0
                                      5-(3,4-Dihydroxyphenyl)-6,7-dimethyl-5,6,7,8-tetrahydronaphthalene-2,3-diol 0
                                      5-Hydroxyenterolactone 0
                                      5-Methoxygalbelgin 0
                                      5-Methoxyhinokinin 0
                                      5-[(6-\{2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]-4-\{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy\}butoxy\}-3,4,5-trihydroxyoxan-2-yl)methoxy]-3-hydroxy-3-methyl-5-oxopentanoic acid 0
                                      5-\{4-[4-(hexopyranosyloxy)-3,5-dimethoxyphenyl]tetrahydro-1H,3H-furo[3,4-c]furan-1-yl\}-2-methoxyphenyl hexopyranoside 0
                                      6'-Hydroxyenterolactone 0
                                      6'-O-desmethyl ES-242-4 0
                                      6-(\{8,11-dihydroxy-17-methoxy-10-oxo-2-oxatricyclo[13.2.2.1?,?]icosa-1(17),3,5,7(20),15,18-hexaen-4-yl\}oxy)-3,4,5-trihydroxyoxane-2-carboxylic acid 0
                                      6-Hydroxyenterodiol 0
                                      6-Hydroxyenterolactone 0
                                      6′-O-desmethyl ES-242-2 0
                                      7-Hydroxyaustrobailignan 5 0
                                      7-Hydroxyenterolactone 0
                                      7-hydroxysecoisolariciresinol 0
                                      8'-Episesaminone 0
                                      8-Acetoxy-4'-methoxypinoresinol 0
                                      8-Acetoxy-4'-methoxypinoresinol 4-glucoside 0
                                      8-Acetoxypinoresinol 0
                                      8-Acetoxypinoresinol 4-glucoside 0
                                      8-Hydroxy-4'-methoxypinoresinol 0
                                      8-Hydroxypinoresinol 0
                                      8-Hydroxypinoresinol 4-glucoside 0
                                      8-Hydroxypinoresinol 8-glucoside 0
                                      A 39183A 0
                                      Anhydropseudophlegmacin-9,10-quinone-3'-amino-8'-O-methyl ether 0
                                      Antibiotic ES 242-5 0
                                      Arctiin 13
                                      Aschantin 0
                                      Austrobailignan 1 0
                                      Austrobailignan 7 0
                                      Austrocolorin A1 0
                                      Austrocolorone B 0
                                      Biondinin B 0
                                      Bioxanthracene 7 0
                                      Carinol 0
                                      Carissanol 0
                                      Caruilignan D 0
                                      Citrusin A 0
                                      Citrusin B 0
                                      Cleistanone(rac) 0
                                      Clemaphenol A 0
                                      Clusin 0
                                      Conoideocrellone A 0
                                      Conoideocrellone B 0
                                      Crisamicin A 0
                                      Crisamicin C 0
                                      Cubebinin 0
                                      Cubebininolide 0
                                      Cubebinone 0
                                      Cycloolivil 0
                                      Dalpanin 0
                                      Dehydrodiferulic dilactone 0
                                      Dihydroclusin 0
                                      Dihydrocubebin, rel- 0
                                      Diphyllin 0
                                      Divanillyltetrahydrofuran ferulate 0
                                      Dongtinganthracene A 0
                                      Dongtinganthracene B 0
                                      Dongtinganthracene C 0
                                      Dongtinganthracene D 0
                                      ES 242-1 0
                                      ES-242-1 0
                                      ES-242-2 0
                                      ES-242-3 0
                                      ES-242-4 0
                                      ES-242-6 0
                                      ES-242-7 0
                                      ES-242-8 0
                                      Eleutheroside E 0
                                      Enterodiol 0
                                      Enterolactone 965
                                      Eucommin A 0
                                      Fargesin 8
                                      Forsythin 0
                                      Fragransin B2 0
                                      Fragransin C1 0
                                      Fragransin D1 0
                                      Fragransin D3 0
                                      G b S r S acetate 0
                                      G b S r S b G acetate 0
                                      G(8-O-4)G' 0
                                      G(8-O-4)G(8-O-4)S(8-5)G' 0
                                      G(8-O-4)G(8-O-4)S(8-8)S 0
                                      G(8-O-4)S(8-8)S(8-O-4)G 0
                                      G(8-O-4)S(8-O-4)S(8-5)G 0
                                      G(8–O–4)S(8–O–4)S(8–8)S 0
                                      G(8–O–4)SP(8–8)S 0
                                      G-8-O-4 -S 0
                                      GTRI-BB 0
                                      Ganschisandrin 0
                                      Gmelinol 0
                                      Grandisin 0
                                      Hemiariensin 0
                                      Heterotropan 0
                                      Hirtusneanoside 0
                                      Isolariciresinol 4'-O-beta-D-glucoside 0
                                      Isolariciresinol 9'-O-alpha-L-arabinofuranoside 0
                                      Isolariciresinol 9'-O-beta-D-glucoside 0
                                      Isolariciresinol 9-O-beta-D-glucoside 0
                                      Isoyatein 0
                                      Justicidin A 0
                                      Justicidin B 0
                                      Justicidin D 0
                                      Karwinskione 0
                                      LSM-20517 0
                                      LSM-34734 0
                                      LSM-4504 0
                                      Labadoside 0
                                      Lappaol C 0
                                      Lappaol D 0
                                      Lariciresinol 4-o-glucoside 0
                                      Ligraminol A 0
                                      Ligraminol B 0
                                      Lugdunomycin 0
                                      Lyoniresinol 9'-sulfate 0
                                      Maculalactone L 0
                                      Magnosalicin 0
                                      Magnosalin 0
                                      Malabaricano 0
                                      Myricatomentoside I 0
                                      Neoarctin A 0
                                      Neoarctin B 0
                                      Neocuscutoside C 0
                                      Neoisostegane 0
                                      Nordihydroguaiaretate 0
                                      Nortrachelogenin 0
                                      O-Ethylcubebin 0
                                      Otobain 0
                                      Otobanone 0
                                      Phyllanthin 4
                                      Phyllanthostatin A 0
                                      Pinoresinol biphenyl 0
                                      Pinoresinol biphenyl acetate 0
                                      Pinoresinol diacetate 0
                                      Pinoresinol diglucoside 0
                                      Plicatic acid 0
                                      Podophyllotoxone 0
                                      Prostalidin A 0
                                      Prupaside 0
                                      Ramontoside 0
                                      Rufoolivacin B 0
                                      Rufoolivacin D 0
                                      Rufoschweinitzin 0
                                      S b S r S 0
                                      S b S r S acetate 0
                                      SP(8-8)S 0
                                      Sanshodiol 0
                                      Saucernetin 0
                                      Secoisolariciresinol 9,9'-diglucoside 0
                                      Sesaminol glucoside 0
                                      Sesaminol glucosyl-(1->2)-glucoside 0
                                      Sesaminone 0
                                      Sesartemin 0
                                      Setomimycin 0
                                      Simplexoside 0
                                      Sinapicolone 0
                                      Sinapiquinone 0
                                      Spirodalesol 0
                                      Ssioriside 0
                                      Steganacin 0
                                      Trachelogenin 4
                                      Tracheloside 0
                                      Veraguensin 0
                                      Xanthoxylol 0
                                      Yangambin 0
                                      [(3S,4S)-5-[(3S)-7-[(2S,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxy-10-hydroxy-9-methoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-10-hydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-4-yl] acetate 0
                                      [(3S,4S)-5-[(3S,4S)-4,10-dihydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-10-hydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-4-yl] acetate 0
                                      [(3S,4S)-6-[(3S)-7-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxy-10-hydroxy-9-methoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-10-hydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-4-yl] acetate 0
                                      [(3S,4S)-6-[(3S,4S)-4-acetyloxy-10-hydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-7,10-dihydroxy-9-methoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-4-yl] acetate 0
                                      [4-(4-hydroxy-3-methoxybenzyl)-2-(4-hydroxy-3-methoxyphenyl)tetrahydro-3-furanyl]methyl hexopyranoside 0
                                      aiphanol 0
                                      alpha-Conidendrin 0
                                      alpha-peltatin + 0
                                      ananolignan B 0
                                      ananolignan C 0
                                      ananolignan D 0
                                      ananolignan E 0
                                      ananolignan F 0
                                      ananolignan G 0
                                      ananolignan H 0
                                      ananolignan I 0
                                      ananolignan J 0
                                      ananolignan K 0
                                      ananolignan L 0
                                      ananolignan M 0
                                      ananolignan N 0
                                      anolignan A 0
                                      anolignan B 0
                                      beilschminol A, rel- 0
                                      beta-D-Glucopyranoside, 2-methoxy-4-[(1S,2S,3S)-1,2,3,4-tetrahydro-3,7-dihydroxy-2,3-bis(hydroxymethyl)-6-methoxy-1-naphthalenyl]phenyl 0
                                      beta-Peltatin A methyl ether 0
                                      beta-peltatin 0
                                      brugunin A 0
                                      buddlenol A 0
                                      buddlenol E 0
                                      burseran 0
                                      cleistanthins + 0
                                      cyclolignane 0
                                      dehydrodiconiferyl dibenzoate 0
                                      demethoxyaschantin 0
                                      deoxypodophyllotoxin 6
                                      dihydroanhydropodorhizol 0
                                      dihydrocubebin 0
                                      enterolactone 3'-sulfate 0
                                      flavonolignan + 140
                                      futokadsurin A 0
                                      futokadsurin B 0
                                      futokadsurin C 0
                                      galgravin 0
                                      graminone B 0
                                      helioxanthin 5
                                      hinokinin 0
                                      interiotherin A 0
                                      interiotherin B 0
                                      interiotherin C 0
                                      isotaxiresinol 0
                                      lignin cw compound-2008 0
                                      lignin cw compound-2024 0
                                      lignin cw compound-2025 0
                                      lignin cw compound-2027 0
                                      lignin cw compound-2030 0
                                      lignin cw compound-2035 0
                                      lignin cw compound-2036 0
                                      lignin cw compound-2059 0
                                      lignin cw compound-2062 0
                                      lignin cw compound-263 0
                                      lignin cw compound-3002 0
                                      lignin cw compound-3014 0
                                      lignin cw compound-3016 0
                                      lignin cw compound-3017 0
                                      lignin cw compound-3018 0
                                      lignin cw compound-3042 0
                                      longipedumin A 0
                                      manassantin A 0
                                      manassantin B 0
                                      matairesinoside 0
                                      meso-3,3'-didemethoxynectandrin B 0
                                      meso-dihydroguaiaretic acid 0
                                      mitopodozide 0
                                      negundin B 0
                                      nordihydroguaiaretic acid + 89
                                      picropodophyllotoxin 16
                                      pinoresinol + 7
                                      podophyllotoxin + 676
                                      rel-(+)-(7'S,8S,8'S)-4,4'-dihydroxy-3',5,5'-trimethoxy-2,7'-cyclolignan 0
                                      rel-(-)-(7S,7'R,8S,8'R)-4,4'-dihydroxy-3,3',5'-trimethoxy-7,7'-epoxylignan 0
                                      rel-(7R,8R,7'R,8'R)-3',4'-methylenedioxy-3,4,5,5'-tetramethoxy-7,7'-epoxylignan 0
                                      rel-(7R,8R,7'R,8'R)-3,4,3',4'-dimethylene-dioxy-5,5'-dimethoxy-7,7'-epoxylignan 0
                                      rel-(7S,8S,7'R,8'R)-3,3',4,4',5,5'-hexamethoxy-7.O.7',8.8'-lignan 0
                                      salicifoliol 0
                                      savinin 0
                                      secoisolariciresinol + 1
                                      styraxin 0
                                      syringaresinol + 11
                                      syringylresinol diacetate 0
                                      taiwanin C 18
                                      tanegool 0
                                      taxiresinol 0
                                      terameprocol 18
                                      vladinol D 0
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