Dnmt1 Rat (+)-catechin decreases activity ISO DNMT1 (Homo sapiens) 6480464 Catechin results in decreased activity of DNMT1 protein CTD PMID:16037419 Dnmt1 Rat (-)-epigallocatechin 3-gallate multiple interactions ISO DNMT1 (Homo sapiens) 6480464 epigallocatechin gallate binds to and results in decreased activity of DNMT1 protein and Magnesium promotes the reaction [epigallocatechin gallate results in decreased activity of DNMT1 protein] CTD PMID:14633667 and PMID:16037419 Dnmt1 Rat (-)-epigallocatechin 3-gallate increases expression ISO DNMT1 (Homo sapiens) 6480464 epigallocatechin gallate results in increased expression of DNMT1 mRNA CTD PMID:25839702 Dnmt1 Rat (-)-epigallocatechin 3-gallate decreases activity ISO DNMT1 (Homo sapiens) 6480464 epigallocatechin gallate results in decreased activity of DNMT1 protein CTD PMID:16037419 Dnmt1 Rat (S)-naringenin multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [naringenin co-treated with bisphenol A] results in increased expression of DNMT1 mRNA and [naringenin metabolite co-treated with bisphenol A] results in increased expression of DNMT1 mRNA CTD PMID:36235125 Dnmt1 Rat (S)-nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of DNMT1 mRNA CTD PMID:28555334 Dnmt1 Rat (S)-nicotine multiple interactions EXP 6480464 Dihydro-beta-Erythroidine analog inhibits the reaction [Nicotine results in decreased expression of DNMT1 mRNA] CTD PMID:28555334 Dnmt1 Rat 1,2-dimethylhydrazine multiple interactions EXP 6480464 [APC protein affects the susceptibility to 1 and 2-Dimethylhydrazine] which results in decreased expression of DNMT1 mRNA CTD PMID:27840820 Dnmt1 Rat 1,2-dimethylhydrazine multiple interactions ISO Dnmt1 (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of DNMT1 mRNA] CTD PMID:22206623 Dnmt1 Rat 1,2-dimethylhydrazine increases expression ISO Dnmt1 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of DNMT1 mRNA CTD PMID:22206623 Dnmt1 Rat 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile affects expression EXP 6480464 Citalopram affects the expression of DNMT1 mRNA CTD PMID:21682946 Dnmt1 Rat 1-chloro-2,4-dinitrobenzene affects binding ISO DNMT1 (Homo sapiens) 6480464 Dinitrochlorobenzene binds to DNMT1 protein CTD PMID:32991956 Dnmt1 Rat 17alpha-ethynylestradiol multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DNMT1 mRNA CTD PMID:17942748 Dnmt1 Rat 17alpha-ethynylestradiol increases expression ISO Dnmt1 (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of DNMT1 mRNA CTD PMID:17942748 Dnmt1 Rat 17beta-estradiol multiple interactions ISO DNMT1 (Homo sapiens) 6480464 6-prenylnaringenin inhibits the reaction [Estradiol promotes the reaction [DNMT1 protein binds to CYP1A1 promoter]] more ... CTD PMID:20631324 more ... Dnmt1 Rat 17beta-estradiol increases expression ISO DNMT1 (Homo sapiens) 6480464 Estradiol results in increased expression of DNMT1 mRNA CTD PMID:30684530 and PMID:32030086 Dnmt1 Rat 17beta-estradiol decreases phosphorylation ISO DNMT1 (Homo sapiens) 6480464 Estradiol results in decreased phosphorylation of DNMT1 protein CTD PMID:27026707 Dnmt1 Rat 17beta-estradiol decreases expression ISO DNMT1 (Homo sapiens) 6480464 Estradiol results in decreased expression of DNMT1 mRNA CTD PMID:22952798 Dnmt1 Rat 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO DNMT1 (Homo sapiens) 6480464 2 more ... CTD PMID:31675489 Dnmt1 Rat 2,3',4,4',5-Pentachlorobiphenyl decreases expression ISO Dnmt1 (Mus musculus) 6480464 2 more ... CTD PMID:31388691 Dnmt1 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DNMT1 mRNA CTD PMID:17942748 Dnmt1 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of DNMT1 mRNA CTD PMID:34747641 Dnmt1 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of DNMT1 mRNA CTD PMID:26455773 Dnmt1 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] promotes the reaction [DNMT1 protein binds to BRCA1 promoter] more ... CTD PMID:20631324 more ... Dnmt1 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [DNMT1 protein binds to BRCA1 promoter]] and Tetrachlorodibenzodioxin promotes the reaction [DNMT1 protein binds to BRCA1 promoter] CTD PMID:24136580 Dnmt1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Dnmt1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of DNMT1 mRNA CTD PMID:21570461 Dnmt1 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Dnmt1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of DNMT1 mRNA CTD PMID:15667827 Dnmt1 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Dnmt1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of DNMT1 mRNA CTD PMID:16611356 Dnmt1 Rat 2,4-D multiple interactions ISO Dnmt1 (Mus musculus) 6480464 2 and 4-Dichlorophenoxyacetic Acid inhibits the reaction [[Sucrose co-treated with Dietary Fats] results in increased expression of DNMT1 mRNA] CTD PMID:37516258 Dnmt1 Rat 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of DNMT1 mRNA CTD PMID:21346803 Dnmt1 Rat 3,3',4,4',5-pentachlorobiphenyl affects expression ISO Dnmt1 (Mus musculus) 6480464 3 more ... CTD PMID:37080397 Dnmt1 Rat 3,3'-diindolylmethane decreases expression ISO DNMT1 (Homo sapiens) 6480464 3 and 3'-diindolylmethane results in decreased expression of DNMT1 mRNA CTD PMID:24466240 Dnmt1 Rat 3,5-diethoxycarbonyl-1,4-dihydrocollidine increases expression ISO Dnmt1 (Mus musculus) 6480464 Dicarbethoxydihydrocollidine results in increased expression of DNMT1 mRNA CTD PMID:18098314 Dnmt1 Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with perfluorooctanoic acid] results in increased expression of DNMT1 mRNA CTD PMID:29094436 Dnmt1 Rat 3-methylcholanthrene multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Methylcholanthrene] affects the expression of and affects the localization of DNMT1 protein CTD PMID:21163286 Dnmt1 Rat 4,4'-sulfonyldiphenol increases expression ISO Dnmt1 (Mus musculus) 6480464 bisphenol S results in increased expression of DNMT1 mRNA CTD PMID:29741722 Dnmt1 Rat 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of DNMT1 mRNA CTD PMID:36041667 Dnmt1 Rat 4,4'-sulfonyldiphenol multiple interactions ISO DNMT1 (Homo sapiens) 6480464 bisphenol S promotes the reaction [ESR1 protein binds to DNMT1 promoter] more ... CTD PMID:32105160 Dnmt1 Rat 4,4'-sulfonyldiphenol increases expression ISO DNMT1 (Homo sapiens) 6480464 bisphenol S results in increased expression of DNMT1 mRNA and bisphenol S results in increased expression of DNMT1 protein CTD PMID:31601247 and PMID:32105160 Dnmt1 Rat 4-\{[4-(dimethylamino)phenyl]diazenyl\}phenyl-beta-lactoside decreases activity ISO DNMT1 (Homo sapiens) 6480464 lac dye results in decreased activity of DNMT1 protein CTD PMID:23839987 Dnmt1 Rat 4-hydroxyphenyl retinamide increases expression ISO Dnmt1 (Mus musculus) 6480464 Fenretinide results in increased expression of DNMT1 mRNA CTD PMID:28973697 Dnmt1 Rat 5-(hydroxymethyl)cytosine multiple interactions ISO DNMT1 (Homo sapiens) 6480464 DNMT1 protein promotes the reaction [bisphenol A results in decreased abundance of 5-hydroxymethylcytosine] and DNMT1 protein promotes the reaction [bisphenol S results in decreased abundance of 5-hydroxymethylcytosine] CTD PMID:32105160 Dnmt1 Rat 5-aza-2'-deoxycytidine multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Decitabine co-treated with sodium arsenite] results in decreased expression of DNMT1 protein more ... CTD PMID:17621267 more ... Dnmt1 Rat 5-aza-2'-deoxycytidine decreases activity EXP 6480464 Decitabine results in decreased activity of DNMT1 protein CTD PMID:21449042 Dnmt1 Rat 5-aza-2'-deoxycytidine increases expression ISO DNMT1 (Homo sapiens) 6480464 Decitabine results in increased expression of DNMT1 mRNA CTD PMID:19117987 Dnmt1 Rat 5-aza-2'-deoxycytidine decreases expression EXP 6480464 Decitabine results in decreased expression of DNMT1 protein CTD PMID:23423710 Dnmt1 Rat 5-aza-2'-deoxycytidine affects response to substance ISO Dnmt1 (Mus musculus) 6480464 DNMT1 affects the susceptibility to Decitabine CTD PMID:14581508 Dnmt1 Rat 5-aza-2'-deoxycytidine decreases expression ISO Dnmt1 (Mus musculus) 6480464 Decitabine results in decreased expression of DNMT1 protein CTD PMID:19222872 and PMID:19679824 Dnmt1 Rat 5-aza-2'-deoxycytidine decreases expression ISO DNMT1 (Homo sapiens) 6480464 Decitabine results in decreased expression of DNMT1 mRNA and Decitabine results in decreased expression of DNMT1 protein CTD PMID:16613325 more ... Dnmt1 Rat 5-aza-2'-deoxycytidine multiple interactions ISO Dnmt1 (Mus musculus) 6480464 Decitabine inhibits the reaction [Particulate Matter promotes the reaction [[ovalbumin-alum co-treated with Ovalbumin] results in increased expression of DNMT1 protein]] and Decitabine inhibits the reaction [Particulate Matter results in increased expression of DNMT1 protein] CTD PMID:30481581 Dnmt1 Rat 5-aza-2'-deoxycytidine affects response to substance ISO DNMT1 (Homo sapiens) 6480464 DNMT1 protein affects the susceptibility to Decitabine CTD PMID:17991895 Dnmt1 Rat 5-aza-2'-deoxycytidine multiple interactions EXP 6480464 Decitabine inhibits the reaction [Dust results in increased expression of DNMT1 mRNA] more ... CTD PMID:24211420 and PMID:30815999 Dnmt1 Rat 5-azacytidine multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [SLC28A1 protein results in increased uptake of Azacitidine] which results in decreased expression of DNMT1 protein more ... CTD PMID:19139132 more ... Dnmt1 Rat 5-azacytidine decreases expression ISO DNMT1 (Homo sapiens) 6480464 Azacitidine results in decreased expression of DNMT1 protein CTD PMID:28901456 Dnmt1 Rat 5-azacytidine decreases expression EXP 6480464 Azacitidine results in decreased expression of DNMT1 protein CTD PMID:19723570 and PMID:21224363 Dnmt1 Rat 5-azacytidine multiple interactions EXP 6480464 [Azacitidine co-treated with entinostat] results in decreased expression of DNMT1 protein and [Cisplatin co-treated with Azacitidine] results in decreased expression of DNMT1 protein CTD PMID:19723570 and PMID:21224363 Dnmt1 Rat 6-prenylnaringenin multiple interactions ISO DNMT1 (Homo sapiens) 6480464 6-prenylnaringenin inhibits the reaction [DNMT1 protein binds to CYP1A1 promoter] and 6-prenylnaringenin inhibits the reaction [Estradiol promotes the reaction [DNMT1 protein binds to CYP1A1 promoter]] CTD PMID:32986415 Dnmt1 Rat 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:12097258 Dnmt1 Rat 7,12-dimethyltetraphene increases expression ISO Dnmt1 (Mus musculus) 6480464 9 more ... CTD PMID:24792773 Dnmt1 Rat 7,12-dimethyltetraphene multiple interactions ISO Dnmt1 (Mus musculus) 6480464 Butyric Acid affects the reaction [9 more ... CTD PMID:24792773 Dnmt1 Rat 8-hydroxy-2'-deoxyguanosine affects abundance ISO DNMT1 (Homo sapiens) 6480464 DNMT1 gene SNP affects the abundance of 8-Hydroxy-2'-Deoxyguanosine CTD PMID:19896490 Dnmt1 Rat 8-hydroxy-2'-deoxyguanosine decreases activity ISO DNMT1 (Homo sapiens) 6480464 8-Hydroxy-2'-Deoxyguanosine results in decreased activity of DNMT1 protein CTD PMID:33052562 Dnmt1 Rat 9-cis-retinoic acid multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Arsenicals co-treated with Alitretinoin] results in increased expression of DNMT1 mRNA and [Arsenicals co-treated with Poly I-C co-treated with Alitretinoin] results in increased expression of DNMT1 mRNA CTD PMID:34303791 Dnmt1 Rat acetamide increases expression EXP 6480464 acetamide results in increased expression of DNMT1 mRNA CTD PMID:31881176 Dnmt1 Rat acetic acid decreases expression ISO DNMT1 (Homo sapiens) 6480464 Acetic Acid results in decreased expression of DNMT1 protein CTD PMID:17065238 Dnmt1 Rat acetylsalicylic acid multiple interactions ISO Dnmt1 (Mus musculus) 6480464 Aspirin inhibits the reaction [Benzo(a)pyrene results in increased expression of DNMT1 mRNA] and Aspirin inhibits the reaction [Benzo(a)pyrene results in increased expression of DNMT1 protein] CTD PMID:34979192 Dnmt1 Rat acrolein increases expression EXP 6480464 Acrolein results in increased expression of DNMT1 mRNA CTD PMID:35150775 Dnmt1 Rat acrolein multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in decreased expression of and results in increased oxidation of DNMT1 mRNA CTD PMID:32845096 Dnmt1 Rat acrylamide decreases expression ISO DNMT1 (Homo sapiens) 6480464 Acrylamide results in decreased expression of DNMT1 mRNA CTD PMID:32763439 Dnmt1 Rat aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of DNMT1 mRNA CTD PMID:33354967 Dnmt1 Rat aldehydo-D-glucose increases expression ISO DNMT1 (Homo sapiens) 6480464 Glucose results in increased expression of DNMT1 mRNA CTD PMID:29854080 Dnmt1 Rat all-trans-retinoic acid decreases expression ISO DNMT1 (Homo sapiens) 6480464 Tretinoin results in decreased expression of DNMT1 mRNA CTD PMID:17273765 and PMID:33167477 Dnmt1 Rat allethrin multiple interactions EXP 6480464 [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of DNMT1 mRNA CTD PMID:33051911 Dnmt1 Rat amitriptyline decreases activity EXP 6480464 Amitriptyline results in decreased activity of DNMT1 protein CTD PMID:19924110 Dnmt1 Rat amitriptyline decreases activity EXP 9588218 Amitriptyline decreases activity of Dnmt1 protein in astrocyte nucleus RGD Dnmt1 Rat amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of DNMT1 mRNA CTD PMID:30779732 Dnmt1 Rat anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO Dnmt1 (Mus musculus) 6480464 pyrazolanthrone inhibits the reaction [Particulate Matter results in increased expression of DNMT1 protein] CTD PMID:22355787 Dnmt1 Rat arsane increases expression EXP 6480464 Arsenic results in increased expression of DNMT1 mRNA CTD PMID:9380733 Dnmt1 Rat arsane decreases expression ISO DNMT1 (Homo sapiens) 6480464 Arsenic results in decreased expression of DNMT1 mRNA CTD PMID:35490796 Dnmt1 Rat arsane multiple interactions ISO DNMT1 (Homo sapiens) 6480464 Folic Acid inhibits the reaction [Arsenic results in decreased expression of DNMT1 mRNA] CTD PMID:35490796 Dnmt1 Rat arsane multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of DNMT1 protein CTD PMID:34952004 Dnmt1 Rat arsane increases expression ISO DNMT1 (Homo sapiens) 6480464 Arsenic results in increased expression of DNMT1 mRNA CTD PMID:27838757 Dnmt1 Rat arsane affects response to substance ISO DNMT1 (Homo sapiens) 6480464 DNMT1 gene SNP affects the susceptibility to Arsenic CTD PMID:27292127 and PMID:31864032 Dnmt1 Rat arsane affects methylation ISO DNMT1 (Homo sapiens) 6480464 Arsenic affects the methylation of DNMT1 gene CTD PMID:25304211 Dnmt1 Rat arsane decreases expression EXP 6480464 Arsenic results in decreased expression of DNMT1 protein CTD PMID:9380733 Dnmt1 Rat arsenic atom decreases expression EXP 6480464 Arsenic results in decreased expression of DNMT1 protein CTD PMID:9380733 Dnmt1 Rat arsenic atom decreases expression ISO DNMT1 (Homo sapiens) 6480464 Arsenic results in decreased expression of DNMT1 mRNA CTD PMID:35490796 Dnmt1 Rat arsenic atom multiple interactions ISO DNMT1 (Homo sapiens) 6480464 Folic Acid inhibits the reaction [Arsenic results in decreased expression of DNMT1 mRNA] CTD PMID:35490796 Dnmt1 Rat arsenic atom multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of DNMT1 protein CTD PMID:34952004 Dnmt1 Rat arsenic atom increases expression ISO DNMT1 (Homo sapiens) 6480464 Arsenic results in increased expression of DNMT1 mRNA CTD PMID:27838757 Dnmt1 Rat arsenic atom affects response to substance ISO DNMT1 (Homo sapiens) 6480464 DNMT1 gene SNP affects the susceptibility to Arsenic CTD PMID:27292127 and PMID:31864032 Dnmt1 Rat arsenic atom affects methylation ISO DNMT1 (Homo sapiens) 6480464 Arsenic affects the methylation of DNMT1 gene CTD PMID:25304211 Dnmt1 Rat arsenic atom increases expression EXP 6480464 Arsenic results in increased expression of DNMT1 mRNA CTD PMID:9380733 Dnmt1 Rat arsenous acid multiple interactions ISO DNMT1 (Homo sapiens) 6480464 Arsenic Trioxide inhibits the reaction [DNMT1 protein binds to ESR1 promoter] more ... CTD PMID:22558281 and PMID:28901456 Dnmt1 Rat arsenous acid decreases expression ISO DNMT1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of DNMT1 mRNA and Arsenic Trioxide results in decreased expression of DNMT1 protein CTD PMID:16613325 more ... Dnmt1 Rat arsenous acid multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [Arsenic Trioxide co-treated with Tamoxifen] results in decreased expression of DNMT1 mRNA and [Arsenic Trioxide co-treated with Tamoxifen] results in decreased expression of DNMT1 protein CTD PMID:23159075 Dnmt1 Rat arsenous acid decreases activity ISO DNMT1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased activity of DNMT1 protein CTD PMID:20596618 Dnmt1 Rat arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of DNMT1 mRNA CTD PMID:29223816 Dnmt1 Rat arsenous acid decreases expression ISO Dnmt1 (Mus musculus) 6480464 Arsenic Trioxide results in decreased expression of DNMT1 mRNA and Arsenic Trioxide results in decreased expression of DNMT1 protein CTD PMID:19679824 and PMID:23159075 Dnmt1 Rat arsenous acid increases expression ISO DNMT1 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of DNMT1 mRNA CTD PMID:25534098 Dnmt1 Rat atrazine decreases expression ISO DNMT1 (Homo sapiens) 6480464 Atrazine results in decreased expression of DNMT1 mRNA CTD PMID:22378314 Dnmt1 Rat benzene increases expression ISO DNMT1 (Homo sapiens) 6480464 Benzene results in increased expression of DNMT1 mRNA CTD PMID:35135009 Dnmt1 Rat benzo[a]pyrene multiple interactions ISO Dnmt1 (Mus musculus) 6480464 Aspirin inhibits the reaction [Benzo(a)pyrene results in increased expression of DNMT1 mRNA] more ... CTD PMID:17682057 and PMID:34979192 Dnmt1 Rat benzo[a]pyrene increases expression ISO DNMT1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of DNMT1 mRNA CTD PMID:32234424 Dnmt1 Rat benzo[a]pyrene increases methylation ISO DNMT1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of DNMT1 promoter CTD PMID:27901495 Dnmt1 Rat benzo[a]pyrene multiple interactions ISO DNMT1 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Benzo(a)pyrene results in increased degradation of DNMT1 protein] CTD PMID:21150308 Dnmt1 Rat benzo[a]pyrene increases degradation ISO DNMT1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased degradation of DNMT1 protein CTD PMID:21150308 Dnmt1 Rat benzo[a]pyrene increases expression ISO Dnmt1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of DNMT1 mRNA and Benzo(a)pyrene results in increased expression of DNMT1 protein CTD PMID:22228805 and PMID:34979192 Dnmt1 Rat benzo[a]pyrene decreases expression ISO Dnmt1 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of DNMT1 mRNA CTD PMID:19770486 Dnmt1 Rat benzophenanthridine decreases expression ISO DNMT1 (Homo sapiens) 6480464 Benzophenanthridines analog results in decreased expression of DNMT1 mRNA CTD PMID:23117580 Dnmt1 Rat berberine decreases expression ISO DNMT1 (Homo sapiens) 6480464 Berberine results in decreased expression of DNMT1 mRNA CTD PMID:27311644 Dnmt1 Rat beta-naphthoflavone decreases expression ISO DNMT1 (Homo sapiens) 6480464 beta-Naphthoflavone results in decreased expression of DNMT1 mRNA CTD PMID:32858204 Dnmt1 Rat bis(2-chloroethyl) sulfide increases expression ISO Dnmt1 (Mus musculus) 6480464 Mustard Gas results in increased expression of DNMT1 mRNA CTD PMID:26392148 Dnmt1 Rat bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of DNMT1 mRNA and Diethylhexyl Phthalate results in increased expression of DNMT1 protein CTD PMID:25280772 and PMID:30597186 Dnmt1 Rat bis(2-ethylhexyl) phthalate affects expression ISO Dnmt1 (Mus musculus) 6480464 Diethylhexyl Phthalate affects the expression of DNMT1 mRNA CTD PMID:32628958 Dnmt1 Rat bis(2-ethylhexyl) phthalate decreases expression ISO Dnmt1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of DNMT1 mRNA CTD PMID:31211961 Dnmt1 Rat bis(2-ethylhexyl) phthalate increases expression ISO Dnmt1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of DNMT1 mRNA CTD PMID:25351189 Dnmt1 Rat bisphenol A multiple interactions ISO Dnmt1 (Mus musculus) 6480464 Drugs more ... CTD PMID:22131059 more ... Dnmt1 Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of DNMT1 mRNA CTD PMID:36041667 Dnmt1 Rat bisphenol A decreases methylation ISO DNMT1 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of DNMT1 gene CTD PMID:31601247 Dnmt1 Rat bisphenol A multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [bisphenol A co-treated with decabromobiphenyl ether] results in decreased expression of DNMT1 mRNA more ... CTD PMID:28597690 more ... Dnmt1 Rat bisphenol A decreases expression ISO DNMT1 (Homo sapiens) 6480464 bisphenol A results in decreased expression of DNMT1 mRNA and bisphenol A results in decreased expression of DNMT1 protein CTD PMID:28597690 more ... Dnmt1 Rat bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of DNMT1 gene CTD PMID:28505145 Dnmt1 Rat bisphenol A increases expression ISO DNMT1 (Homo sapiens) 6480464 bisphenol A results in increased expression of DNMT1 mRNA and bisphenol A results in increased expression of DNMT1 protein CTD PMID:28765096 more ... Dnmt1 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of DNMT1 mRNA CTD PMID:25181051 more ... Dnmt1 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of DNMT1 mRNA and bisphenol A results in increased expression of DNMT1 protein CTD PMID:23791455 and PMID:32450286 Dnmt1 Rat bisphenol A affects methylation ISO Dnmt1 (Mus musculus) 6480464 bisphenol A affects the methylation of DNMT1 exon CTD PMID:23716699 Dnmt1 Rat bisphenol A affects expression ISO Dnmt1 (Mus musculus) 6480464 bisphenol A affects the expression of DNMT1 mRNA CTD PMID:23716699 and PMID:31201698 Dnmt1 Rat bisphenol A increases expression ISO Dnmt1 (Mus musculus) 6480464 bisphenol A results in increased expression of DNMT1 mRNA and bisphenol A results in increased expression of DNMT1 protein CTD PMID:25385582 more ... Dnmt1 Rat bisphenol A decreases expression ISO Dnmt1 (Mus musculus) 6480464 bisphenol A results in decreased expression of DNMT1 mRNA and bisphenol A results in decreased expression of DNMT1 protein CTD PMID:21980460 more ... Dnmt1 Rat bisphenol F increases expression ISO DNMT1 (Homo sapiens) 6480464 bisphenol F results in increased expression of DNMT1 mRNA CTD PMID:31601247 Dnmt1 Rat bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of DNMT1 mRNA CTD PMID:36041667 Dnmt1 Rat bleomycin A2 affects response to substance ISO DNMT1 (Homo sapiens) 6480464 DNMT1 protein affects the susceptibility to Bleomycin CTD PMID:17991895 Dnmt1 Rat Brodifacoum affects binding ISO DNMT1 (Homo sapiens) 6480464 bromfenacoum binds to DNMT1 protein CTD PMID:31595789 Dnmt1 Rat buta-1,3-diene decreases expression ISO Dnmt1 (Mus musculus) 6480464 1 more ... CTD PMID:21147608 more ... Dnmt1 Rat butyric acid multiple interactions ISO Dnmt1 (Mus musculus) 6480464 Butyric Acid affects the reaction [9 more ... CTD PMID:24792773 Dnmt1 Rat cadmium atom decreases activity EXP 6480464 Cadmium results in decreased activity of DNMT1 protein CTD PMID:21449042 Dnmt1 Rat cadmium atom affects response to substance ISO DNMT1 (Homo sapiens) 6480464 DNMT1 gene SNP affects the susceptibility to Cadmium CTD PMID:22382075 Dnmt1 Rat cadmium dichloride multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased activity of [DNMT1 protein co-treated with DNMT3A protein]] which results in decreased expression of ERCC1 mRNA more ... CTD PMID:22112500 Dnmt1 Rat cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of DNMT1 mRNA CTD PMID:35525383 Dnmt1 Rat cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of DNMT1 mRNA and Cadmium Chloride results in decreased expression of DNMT1 protein CTD PMID:33865896 Dnmt1 Rat cadmium dichloride increases expression ISO DNMT1 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of DNMT1 mRNA and Cadmium Chloride results in increased expression of DNMT1 protein CTD PMID:22112500 more ... Dnmt1 Rat caffeine increases expression EXP 6480464 Caffeine results in increased expression of DNMT1 mRNA CTD PMID:24717552 Dnmt1 Rat caffeine affects phosphorylation ISO DNMT1 (Homo sapiens) 6480464 Caffeine affects the phosphorylation of DNMT1 protein CTD PMID:35688186 Dnmt1 Rat calciol decreases expression ISO DNMT1 (Homo sapiens) 6480464 Cholecalciferol results in decreased expression of DNMT1 mRNA CTD PMID:21801466 Dnmt1 Rat calciol multiple interactions ISO DNMT1 (Homo sapiens) 6480464 Cholecalciferol promotes the reaction [Cladribine results in decreased expression of DNMT1 mRNA] and Cladribine promotes the reaction [Cholecalciferol results in decreased expression of DNMT1 mRNA] CTD PMID:21801466 Dnmt1 Rat calcitriol decreases expression ISO DNMT1 (Homo sapiens) 6480464 Calcitriol results in decreased expression of DNMT1 mRNA CTD PMID:21592394 Dnmt1 Rat calcitriol multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of DNMT1 mRNA CTD PMID:21592394 Dnmt1 Rat cantharidin decreases expression ISO DNMT1 (Homo sapiens) 6480464 Cantharidin results in decreased expression of DNMT1 mRNA CTD PMID:32726682 Dnmt1 Rat carbon nanotube increases expression ISO Dnmt1 (Mus musculus) 6480464 Nanotubes and Carbon analog results in increased expression of DNMT1 mRNA CTD PMID:25554681 Dnmt1 Rat casticin multiple interactions ISO DNMT1 (Homo sapiens) 6480464 casticin affects the reaction [MIR148A mRNA affects the activity of DNMT1 protein] more ... CTD PMID:32268151 Dnmt1 Rat casticin decreases activity ISO DNMT1 (Homo sapiens) 6480464 casticin results in decreased activity of DNMT1 protein CTD PMID:32268151 Dnmt1 Rat casticin decreases expression ISO DNMT1 (Homo sapiens) 6480464 casticin results in decreased expression of DNMT1 mRNA CTD PMID:32268151 Dnmt1 Rat chlorpyrifos decreases expression ISO Dnmt1 (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of DNMT1 mRNA CTD PMID:37019170 Dnmt1 Rat choline affects activity ISO Dnmt1 (Mus musculus) 6480464 Choline affects the activity of DNMT1 protein CTD PMID:16855792 Dnmt1 Rat choline multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency co-treated with sodium arsenite] results in decreased expression of DNMT1 mRNA more ... CTD PMID:20978746 and PMID:25690533 Dnmt1 Rat chromium atom multiple interactions ISO Dnmt1 (Mus musculus) 6480464 Chromium promotes the reaction [[DNMT1 protein binds to HDAC1 protein] which binds to CYP1A1 promoter] CTD PMID:17682057 Dnmt1 Rat cisplatin decreases response to substance EXP 6480464 DNMT1 protein results in decreased susceptibility to Cisplatin CTD PMID:18314485 Dnmt1 Rat cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of DNMT1 protein CTD PMID:19723570 Dnmt1 Rat cisplatin multiple interactions EXP 6480464 [Cisplatin co-treated with Azacitidine] results in decreased expression of DNMT1 protein CTD PMID:19723570 Dnmt1 Rat cisplatin decreases response to substance ISO DNMT1 (Homo sapiens) 6480464 DNMT1 protein results in decreased susceptibility to Cisplatin CTD PMID:18314485 and PMID:21458988 Dnmt1 Rat citalopram affects expression EXP 6480464 Citalopram affects the expression of DNMT1 mRNA CTD PMID:21682946 Dnmt1 Rat cladribine decreases expression ISO DNMT1 (Homo sapiens) 6480464 Cladribine results in decreased expression of DNMT1 mRNA CTD PMID:21801466 Dnmt1 Rat cladribine multiple interactions ISO DNMT1 (Homo sapiens) 6480464 Cholecalciferol promotes the reaction [Cladribine results in decreased expression of DNMT1 mRNA] and Cladribine promotes the reaction [Cholecalciferol results in decreased expression of DNMT1 mRNA] CTD PMID:21801466 Dnmt1 Rat clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of DNMT1 mRNA and Clofibrate results in decreased expression of DNMT1 protein CTD PMID:28495587 Dnmt1 Rat cobalt dichloride decreases expression ISO DNMT1 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of DNMT1 mRNA CTD PMID:19320972 Dnmt1 Rat copper atom multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in decreased expression of DNMT1 mRNA CTD PMID:20971185 Dnmt1 Rat copper atom decreases expression ISO DNMT1 (Homo sapiens) 6480464 Copper results in decreased expression of DNMT1 mRNA CTD PMID:34871762 Dnmt1 Rat copper(0) multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in decreased expression of DNMT1 mRNA CTD PMID:20971185 Dnmt1 Rat copper(0) decreases expression ISO DNMT1 (Homo sapiens) 6480464 Copper results in decreased expression of DNMT1 mRNA CTD PMID:34871762 Dnmt1 Rat coumarin increases phosphorylation ISO DNMT1 (Homo sapiens) 6480464 coumarin results in increased phosphorylation of DNMT1 protein CTD PMID:35688186 Dnmt1 Rat coumestrol multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:19167446 Dnmt1 Rat coumestrol increases expression ISO DNMT1 (Homo sapiens) 6480464 Coumestrol results in increased expression of DNMT1 mRNA CTD PMID:19167446 Dnmt1 Rat crocidolite asbestos increases expression ISO DNMT1 (Homo sapiens) 6480464 Asbestos more ... CTD PMID:32006662 Dnmt1 Rat Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of DNMT1 mRNA CTD PMID:26577399 Dnmt1 Rat curcumin decreases expression ISO DNMT1 (Homo sapiens) 6480464 Curcumin results in decreased expression of DNMT1 mRNA and Curcumin results in decreased expression of DNMT1 protein CTD PMID:23593078 Dnmt1 Rat curcumin affects expression ISO Dnmt1 (Mus musculus) 6480464 Curcumin analog affects the expression of DNMT1 protein CTD PMID:29228771 Dnmt1 Rat curcumin multiple interactions ISO DNMT1 (Homo sapiens) 6480464 Curcumin promotes the reaction [Quercetin results in increased activity of DNMT1 protein] and Quercetin promotes the reaction [Curcumin results in increased activity of DNMT1 protein] CTD PMID:27132804 Dnmt1 Rat curcumin increases activity ISO DNMT1 (Homo sapiens) 6480464 Curcumin results in increased activity of DNMT1 protein CTD PMID:27132804 Dnmt1 Rat curcumin decreases expression ISO Dnmt1 (Mus musculus) 6480464 Curcumin analog results in decreased expression of DNMT1 protein CTD PMID:26991801 Dnmt1 Rat cyclophosphamide multiple interactions ISO DNMT1 (Homo sapiens) 6480464 Cyclophosphamide promotes the reaction [KDM1A protein results in decreased methylation of and results in decreased degradation of DNMT1 protein] and SGI-1027 promotes the reaction [Cyclophosphamide results in decreased expression of DNMT1 protein] CTD PMID:22007908 and PMID:34658283 Dnmt1 Rat cyclophosphamide decreases expression ISO DNMT1 (Homo sapiens) 6480464 Cyclophosphamide results in decreased expression of DNMT1 protein CTD PMID:34658283 Dnmt1 Rat cyclophosphamide increases expression ISO DNMT1 (Homo sapiens) 6480464 Cyclophosphamide results in increased expression of DNMT1 protein CTD PMID:22007908 Dnmt1 Rat cyclophosphamide decreases methylation ISO DNMT1 (Homo sapiens) 6480464 Cyclophosphamide results in decreased methylation of DNMT1 protein CTD PMID:22007908 Dnmt1 Rat cyclosporin A increases expression ISO Dnmt1 (Mus musculus) 6480464 Cyclosporine results in increased expression of DNMT1 mRNA CTD PMID:19770486 Dnmt1 Rat cyclosporin A decreases expression ISO DNMT1 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of DNMT1 mRNA CTD PMID:25562108 Dnmt1 Rat cyhalothrin multiple interactions EXP 6480464 [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of DNMT1 mRNA CTD PMID:33051911 Dnmt1 Rat cypermethrin multiple interactions EXP 6480464 [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of DNMT1 mRNA CTD PMID:33051911 Dnmt1 Rat cypermethrin increases expression EXP 6480464 cypermethrin results in increased expression of DNMT1 mRNA CTD PMID:35605701 Dnmt1 Rat D-glucose increases expression ISO DNMT1 (Homo sapiens) 6480464 Glucose results in increased expression of DNMT1 mRNA CTD PMID:29854080 Dnmt1 Rat daidzein multiple interactions EXP 6480464 [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 Dnmt1 Rat daidzein 7-O-beta-D-glucoside multiple interactions EXP 6480464 [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 Dnmt1 Rat DDE decreases expression EXP 6480464 Dichlorodiphenyl Dichloroethylene results in decreased expression of DNMT1 mRNA CTD PMID:30153481 Dnmt1 Rat DDT decreases expression EXP 6480464 DDT results in decreased expression of DNMT1 mRNA CTD PMID:19797855 Dnmt1 Rat DDT increases expression EXP 6480464 DDT results in increased expression of DNMT1 mRNA and DDT results in increased expression of DNMT1 protein CTD PMID:25410620 Dnmt1 Rat decabromodiphenyl ether multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [bisphenol A co-treated with decabromobiphenyl ether] results in decreased expression of DNMT1 mRNA CTD PMID:28597690 Dnmt1 Rat decabromodiphenyl ether decreases expression ISO DNMT1 (Homo sapiens) 6480464 decabromobiphenyl ether results in decreased expression of DNMT1 mRNA CTD PMID:28597690 Dnmt1 Rat deoxynivalenol increases expression EXP 6480464 deoxynivalenol results in increased expression of DNMT1 mRNA and deoxynivalenol results in increased expression of DNMT1 protein CTD PMID:32738333 Dnmt1 Rat deoxynivalenol affects phosphorylation ISO Dnmt1 (Mus musculus) 6480464 deoxynivalenol affects the phosphorylation of DNMT1 protein CTD PMID:23352502 and PMID:23811945 Dnmt1 Rat desferrioxamine B increases expression ISO DNMT1 (Homo sapiens) 6480464 Deferoxamine results in increased expression of DNMT1 mRNA CTD PMID:23483119 Dnmt1 Rat desferrioxamine B decreases expression ISO DNMT1 (Homo sapiens) 6480464 Deferoxamine results in decreased expression of DNMT1 mRNA CTD PMID:23483119 Dnmt1 Rat dexamethasone multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with perfluorooctanoic acid] results in increased expression of DNMT1 mRNA CTD PMID:29094436 Dnmt1 Rat diarsenic trioxide decreases expression ISO DNMT1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of DNMT1 mRNA and Arsenic Trioxide results in decreased expression of DNMT1 protein CTD PMID:16613325 more ... Dnmt1 Rat diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of DNMT1 mRNA CTD PMID:29223816 Dnmt1 Rat diarsenic trioxide multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [Arsenic Trioxide co-treated with Tamoxifen] results in decreased expression of DNMT1 mRNA and [Arsenic Trioxide co-treated with Tamoxifen] results in decreased expression of DNMT1 protein CTD PMID:23159075 Dnmt1 Rat diarsenic trioxide decreases expression ISO Dnmt1 (Mus musculus) 6480464 Arsenic Trioxide results in decreased expression of DNMT1 mRNA and Arsenic Trioxide results in decreased expression of DNMT1 protein CTD PMID:19679824 and PMID:23159075 Dnmt1 Rat diarsenic trioxide multiple interactions ISO DNMT1 (Homo sapiens) 6480464 Arsenic Trioxide inhibits the reaction [DNMT1 protein binds to ESR1 promoter] more ... CTD PMID:22558281 and PMID:28901456 Dnmt1 Rat diarsenic trioxide decreases activity ISO DNMT1 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased activity of DNMT1 protein CTD PMID:20596618 Dnmt1 Rat diarsenic trioxide increases expression ISO DNMT1 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of DNMT1 mRNA CTD PMID:25534098 Dnmt1 Rat dibutyl phthalate decreases expression ISO Dnmt1 (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of DNMT1 mRNA CTD PMID:21266533 and PMID:31318015 Dnmt1 Rat dibutyl phthalate increases expression ISO Dnmt1 (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of DNMT1 protein CTD PMID:36602389 Dnmt1 Rat dicrotophos increases expression ISO DNMT1 (Homo sapiens) 6480464 dicrotophos results in increased expression of DNMT1 mRNA CTD PMID:28302478 Dnmt1 Rat diethylstilbestrol increases expression ISO Dnmt1 (Mus musculus) 6480464 Diethylstilbestrol results in increased expression of DNMT1 mRNA CTD PMID:16714842 Dnmt1 Rat diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of DNMT1 mRNA CTD PMID:35605701 Dnmt1 Rat Difenacoum affects binding ISO DNMT1 (Homo sapiens) 6480464 difenacoum binds to DNMT1 protein CTD PMID:31595789 Dnmt1 Rat dihydro-beta-erythroidine multiple interactions EXP 6480464 Dihydro-beta-Erythroidine analog inhibits the reaction [Nicotine results in decreased expression of DNMT1 mRNA] CTD PMID:28555334 Dnmt1 Rat dimethyl sulfate decreases expression ISO DNMT1 (Homo sapiens) 6480464 dimethyl sulfate results in decreased expression of DNMT1 protein CTD PMID:11912126 Dnmt1 Rat dimethyl sulfoxide decreases expression ISO DNMT1 (Homo sapiens) 6480464 Dimethyl Sulfoxide results in decreased expression of DNMT1 protein CTD PMID:17065238 Dnmt1 Rat dioxygen increases expression ISO DNMT1 (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of DNMT1 protein CTD PMID:18314485 Dnmt1 Rat dioxygen decreases expression ISO DNMT1 (Homo sapiens) 6480464 Oxygen deficiency results in decreased expression of DNMT1 mRNA CTD PMID:26516004 Dnmt1 Rat disodium cromoglycate decreases expression ISO DNMT1 (Homo sapiens) 6480464 Cromolyn Sodium results in decreased expression of DNMT1 mRNA and Cromolyn Sodium results in decreased expression of DNMT1 protein CTD PMID:35961540 Dnmt1 Rat disodium selenite decreases expression ISO DNMT1 (Homo sapiens) 6480464 Sodium Selenite results in decreased expression of DNMT1 mRNA and Sodium Selenite results in decreased expression of DNMT1 protein CTD PMID:18676679 Dnmt1 Rat doxorubicin affects response to substance ISO DNMT1 (Homo sapiens) 6480464 DNMT1 protein affects the susceptibility to Doxorubicin CTD PMID:17991895 Dnmt1 Rat doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of DNMT1 mRNA CTD PMID:30557669 Dnmt1 Rat doxorubicin multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Doxorubicin inhibits the reaction [DNMT1 binds to RELN promoter]] which results in increased expression of RELN mRNA more ... CTD PMID:17065238 more ... Dnmt1 Rat elemental selenium affects activity EXP 6480464 Selenium affects the activity of DNMT1 protein CTD PMID:16632891 Dnmt1 Rat endosulfan increases expression ISO DNMT1 (Homo sapiens) 6480464 Endosulfan results in increased expression of DNMT1 mRNA and Endosulfan results in increased expression of DNMT1 protein CTD PMID:29054638 Dnmt1 Rat Enterolactone multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DNMT1 mRNA CTD PMID:19167446 Dnmt1 Rat entinostat multiple interactions EXP 6480464 [Azacitidine co-treated with entinostat] results in decreased expression of DNMT1 protein CTD PMID:21224363 Dnmt1 Rat enzyme inhibitor multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of DNMT1 protein CTD PMID:23301498 Dnmt1 Rat escitalopram decreases expression EXP 9588311 Escitalopram decreases expression of Dnmt1 mRNA in FSL strain prefrontal cortex RGD Dnmt1 Rat ethanol decreases expression ISO Dnmt1 (Mus musculus) 6480464 Ethanol results in decreased expression of DNMT1 mRNA and Ethanol results in decreased expression of DNMT1 protein CTD PMID:23395981 Dnmt1 Rat ethanol affects splicing ISO Dnmt1 (Mus musculus) 6480464 Ethanol affects the splicing of DNMT1 mRNA CTD PMID:30319688 Dnmt1 Rat ethanol increases degradation ISO Dnmt1 (Mus musculus) 6480464 Ethanol results in increased degradation of DNMT1 protein CTD PMID:23395981 Dnmt1 Rat ethanol multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of DNMT1 mRNA and benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of DNMT1 protein] CTD PMID:23395981 and PMID:30517762 Dnmt1 Rat etoposide decreases response to substance EXP 6480464 DNMT1 protein results in decreased susceptibility to Etoposide CTD PMID:18314485 Dnmt1 Rat etoposide decreases response to substance ISO DNMT1 (Homo sapiens) 6480464 DNMT1 protein results in decreased susceptibility to Etoposide CTD PMID:18314485 Dnmt1 Rat fenthion decreases expression ISO Dnmt1 (Mus musculus) 6480464 Fenthion results in decreased expression of DNMT1 mRNA CTD PMID:34813904 Dnmt1 Rat fenvalerate multiple interactions EXP 6480464 [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] affects the expression of DNMT1 mRNA CTD PMID:33051911 Dnmt1 Rat fisetin multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [fisetin co-treated with COMT protein] results in decreased activity of DNMT1 protein CTD PMID:16037419 Dnmt1 Rat Flocoumafen affects binding ISO DNMT1 (Homo sapiens) 6480464 flocoumafen binds to DNMT1 protein CTD PMID:31595789 Dnmt1 Rat folic acid affects expression ISO DNMT1 (Homo sapiens) 6480464 Folic Acid affects the expression of DNMT1 mRNA CTD PMID:17311948 and PMID:26492244 Dnmt1 Rat folic acid increases expression ISO DNMT1 (Homo sapiens) 6480464 Folic Acid results in increased expression of DNMT1 mRNA CTD PMID:23219837 Dnmt1 Rat folic acid multiple interactions ISO DNMT1 (Homo sapiens) 6480464 APP protein affects the reaction [Folic Acid affects the expression of DNMT1 mRNA] and Folic Acid inhibits the reaction [Arsenic results in decreased expression of DNMT1 mRNA] CTD PMID:26492244 and PMID:35490796 Dnmt1 Rat folic acid affects expression ISO Dnmt1 (Mus musculus) 6480464 Folic Acid affects the expression of DNMT1 mRNA CTD PMID:29986310 Dnmt1 Rat folic acid increases expression ISO Dnmt1 (Mus musculus) 6480464 Folic Acid results in increased expression of DNMT1 mRNA and Folic Acid results in increased expression of DNMT1 protein CTD PMID:30920123 Dnmt1 Rat folic acid multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency co-treated with sodium arsenite] results in decreased expression of DNMT1 mRNA more ... CTD PMID:20978746 more ... Dnmt1 Rat folic acid affects activity ISO Dnmt1 (Mus musculus) 6480464 Folic Acid affects the activity of DNMT1 protein CTD PMID:16855792 Dnmt1 Rat formaldehyde increases expression ISO DNMT1 (Homo sapiens) 6480464 Formaldehyde results in increased expression of DNMT1 mRNA and Formaldehyde results in increased expression of DNMT1 protein CTD PMID:21745553 Dnmt1 Rat FR900359 decreases phosphorylation ISO DNMT1 (Homo sapiens) 6480464 FR900359 results in decreased phosphorylation of DNMT1 protein CTD PMID:37730182 Dnmt1 Rat fulvestrant multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Fulvestrant co-treated with Sirolimus] results in decreased expression of DNMT1 mRNA more ... CTD PMID:19016759 more ... Dnmt1 Rat fulvestrant multiple interactions ISO Dnmt1 (Mus musculus) 6480464 Fulvestrant inhibits the reaction [bisphenol A results in decreased expression of DNMT1 mRNA] and Fulvestrant inhibits the reaction [bisphenol A results in increased expression of DNMT1 mRNA] CTD PMID:22131059 and PMID:30892605 Dnmt1 Rat fulvestrant decreases expression ISO DNMT1 (Homo sapiens) 6480464 Fulvestrant results in decreased expression of DNMT1 mRNA CTD PMID:19016759 and PMID:31601247 Dnmt1 Rat fumonisin B1 decreases activity ISO DNMT1 (Homo sapiens) 6480464 fumonisin B1 results in decreased activity of DNMT1 protein CTD PMID:24280379 Dnmt1 Rat gemcitabine multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [DNMT1 protein binds to SFN promoter] inhibits the reaction [Gemcitabine results in decreased susceptibility to Gemcitabine] more ... CTD PMID:25189999 Dnmt1 Rat Geniposide multiple interactions ISO DNMT1 (Homo sapiens) 6480464 geniposide inhibits the reaction [Hydrogen Peroxide results in decreased expression of DNMT1 mRNA] and geniposide inhibits the reaction [Hydrogen Peroxide results in decreased expression of DNMT1 protein] CTD PMID:37940031 Dnmt1 Rat genistein decreases expression ISO DNMT1 (Homo sapiens) 6480464 Genistein results in decreased expression of DNMT1 mRNA and Genistein results in decreased expression of DNMT1 protein CTD PMID:16705744 more ... Dnmt1 Rat genistein multiple interactions ISO DNMT1 (Homo sapiens) 6480464 sulforaphane inhibits the reaction [Genistein results in increased expression of DNMT1 mRNA] CTD PMID:30684530 Dnmt1 Rat genistein increases expression ISO DNMT1 (Homo sapiens) 6480464 Genistein results in increased expression of DNMT1 mRNA CTD PMID:30684530 Dnmt1 Rat genistein multiple interactions EXP 6480464 [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 Dnmt1 Rat genistein 7-O-beta-D-glucoside multiple interactions EXP 6480464 [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 Dnmt1 Rat glucaric acid multiple interactions ISO Dnmt1 (Mus musculus) 6480464 Glucaric Acid affects the reaction [9 more ... CTD PMID:24792773 Dnmt1 Rat glucose increases expression ISO DNMT1 (Homo sapiens) 6480464 Glucose results in increased expression of DNMT1 mRNA CTD PMID:29854080 Dnmt1 Rat glycine betaine multiple interactions ISO Dnmt1 (Mus musculus) 6480464 Betaine inhibits the reaction [CPT1A protein mutant form results in decreased expression of DNMT1 mRNA] CTD PMID:22945834 Dnmt1 Rat glycine betaine increases expression ISO Dnmt1 (Mus musculus) 6480464 Betaine results in increased expression of DNMT1 mRNA CTD PMID:22945834 Dnmt1 Rat glycitein multiple interactions EXP 6480464 [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 Dnmt1 Rat glycitin multiple interactions EXP 6480464 [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 Dnmt1 Rat glyphosate increases expression ISO DNMT1 (Homo sapiens) 6480464 Glyphosate results in increased expression of DNMT1 mRNA CTD PMID:33803994 Dnmt1 Rat guggulsterone decreases expression ISO DNMT1 (Homo sapiens) 6480464 pregna-4 more ... CTD PMID:23593078 Dnmt1 Rat hexadecanoic acid increases phosphorylation ISO DNMT1 (Homo sapiens) 6480464 Palmitic Acid results in increased phosphorylation of DNMT1 protein CTD PMID:28073184 Dnmt1 Rat hexane decreases methylation EXP 6480464 n-hexane results in decreased methylation of DNMT1 promoter CTD PMID:23740543 Dnmt1 Rat homocysteine decreases activity ISO DNMT1 (Homo sapiens) 6480464 Homocysteine results in decreased activity of DNMT1 protein CTD PMID:17698632 Dnmt1 Rat homocysteine multiple interactions ISO DNMT1 (Homo sapiens) 6480464 DNMT1 protein affects the reaction [Homocysteine results in decreased expression of CCNA1 mRNA] CTD PMID:17698632 Dnmt1 Rat hydrogen peroxide increases expression ISO DNMT1 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of DNMT1 mRNA and Hydrogen Peroxide results in increased expression of DNMT1 protein CTD PMID:18314485 and PMID:27655674 Dnmt1 Rat hydrogen peroxide decreases expression ISO DNMT1 (Homo sapiens) 6480464 Hydrogen Peroxide results in decreased expression of DNMT1 mRNA and Hydrogen Peroxide results in decreased expression of DNMT1 protein CTD PMID:37940031 Dnmt1 Rat hydrogen peroxide multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Acetylcysteine co-treated with Hydrogen Peroxide] results in increased expression of DNMT1 mRNA more ... CTD PMID:29854080 and PMID:37940031 Dnmt1 Rat hydrogen peroxide decreases response to substance EXP 6480464 DNMT1 protein results in decreased susceptibility to Hydrogen Peroxide CTD PMID:18314485 Dnmt1 Rat hydrogen peroxide decreases response to substance ISO DNMT1 (Homo sapiens) 6480464 DNMT1 protein results in decreased susceptibility to Hydrogen Peroxide CTD PMID:18314485 Dnmt1 Rat hydroquinone decreases expression ISO DNMT1 (Homo sapiens) 6480464 hydroquinone results in decreased expression of DNMT1 mRNA and hydroquinone results in decreased expression of DNMT1 protein CTD PMID:22245671 more ... Dnmt1 Rat hydroquinone increases expression ISO DNMT1 (Homo sapiens) 6480464 hydroquinone results in increased expression of DNMT1 mRNA CTD PMID:35135009 Dnmt1 Rat hydroquinone affects expression ISO DNMT1 (Homo sapiens) 6480464 hydroquinone affects the expression of DNMT1 mRNA CTD PMID:31899212 Dnmt1 Rat hydroxyurea affects response to substance ISO DNMT1 (Homo sapiens) 6480464 DNMT1 protein affects the susceptibility to Hydroxyurea CTD PMID:17991895 Dnmt1 Rat hypochlorous acid decreases expression ISO Dnmt1 (Mus musculus) 6480464 Hypochlorous Acid results in decreased expression of DNMT1 mRNA CTD PMID:19376150 Dnmt1 Rat ionomycin multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein more ... CTD PMID:23775084 Dnmt1 Rat Isorhapontigenin multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of DNMT1 protein CTD PMID:37619952 Dnmt1 Rat ivermectin decreases expression ISO DNMT1 (Homo sapiens) 6480464 Ivermectin results in decreased expression of DNMT1 protein CTD PMID:32959892 Dnmt1 Rat L-methionine multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency co-treated with sodium arsenite] results in decreased expression of DNMT1 mRNA more ... CTD PMID:20978746 and PMID:25690533 Dnmt1 Rat L-methionine decreases expression ISO Dnmt1 (Mus musculus) 6480464 Methionine deficiency results in decreased expression of DNMT1 mRNA and Methionine results in decreased expression of DNMT1 mRNA CTD PMID:35314295 Dnmt1 Rat lead diacetate decreases expression EXP 6480464 lead acetate results in decreased expression of DNMT1 mRNA and lead acetate results in decreased expression of DNMT1 protein CTD PMID:21117136 more ... Dnmt1 Rat lead diacetate multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [lead acetate results in increased abundance of Lead] which affects the expression of DNMT1 protein CTD PMID:29481626 Dnmt1 Rat lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of DNMT1 mRNA and lead acetate results in increased expression of DNMT1 protein CTD PMID:22160880 and PMID:23246732 Dnmt1 Rat lead(0) decreases expression ISO Dnmt1 (Mus musculus) 6480464 Lead results in decreased expression of DNMT1 mRNA and Lead results in decreased expression of DNMT1 protein CTD PMID:27239543 Dnmt1 Rat lead(0) multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [lead acetate results in increased abundance of Lead] which affects the expression of DNMT1 protein CTD PMID:29481626 Dnmt1 Rat lead(0) decreases expression ISO DNMT1 (Homo sapiens) 6480464 Lead results in decreased expression of DNMT1 mRNA and Lead results in decreased expression of DNMT1 protein CTD PMID:22272629 Dnmt1 Rat leptomycin B multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [leptomycin B co-treated with TP53 gene mutant form] results in decreased expression of DNMT1 mRNA CTD PMID:20803015 Dnmt1 Rat leptomycin B decreases expression ISO DNMT1 (Homo sapiens) 6480464 leptomycin B results in decreased expression of DNMT1 mRNA CTD PMID:20803015 Dnmt1 Rat linsidomine increases oxidation EXP 6480464 linsidomine results in increased oxidation of DNMT1 protein CTD PMID:28086193 Dnmt1 Rat magnesium atom decreases activity ISO DNMT1 (Homo sapiens) 6480464 Magnesium results in decreased activity of DNMT1 protein CTD PMID:16037419 Dnmt1 Rat magnesium atom multiple interactions ISO DNMT1 (Homo sapiens) 6480464 Magnesium promotes the reaction [epigallocatechin gallate results in decreased activity of DNMT1 protein] CTD PMID:16037419 Dnmt1 Rat malathion decreases expression EXP 6480464 Malathion results in decreased expression of DNMT1 mRNA CTD PMID:36370973 Dnmt1 Rat mancozeb decreases expression ISO Dnmt1 (Mus musculus) 6480464 mancozeb results in decreased expression of DNMT1 protein CTD PMID:36007320 Dnmt1 Rat metformin multiple interactions EXP 6480464 Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 mRNA]] and Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 protein]] CTD PMID:36547818 Dnmt1 Rat methamphetamine decreases expression EXP 6480464 Methamphetamine results in decreased expression of DNMT1 mRNA CTD PMID:17254711 Dnmt1 Rat methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of DNMT1 mRNA CTD PMID:17254711 Dnmt1 Rat methyl methanesulfonate decreases expression ISO DNMT1 (Homo sapiens) 6480464 Methyl Methanesulfonate results in decreased expression of DNMT1 protein CTD PMID:11912126 Dnmt1 Rat methyl methanesulfonate increases degradation ISO DNMT1 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased degradation of DNMT1 protein CTD PMID:11912126 Dnmt1 Rat methylarsonic acid decreases expression EXP 6480464 monomethylarsonic acid results in decreased expression of DNMT1 mRNA CTD PMID:17481689 Dnmt1 Rat methylmercury chloride decreases expression EXP 6480464 methylmercuric chloride results in decreased expression of DNMT1 mRNA CTD PMID:19636072 Dnmt1 Rat methylmercury chloride increases expression ISO Dnmt1 (Mus musculus) 6480464 methylmercuric chloride results in increased expression of DNMT1 protein CTD PMID:33454822 Dnmt1 Rat methylmercury chloride increases expression ISO DNMT1 (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of DNMT1 protein CTD PMID:33454822 Dnmt1 Rat mitomycin C decreases expression ISO Dnmt1 (Mus musculus) 6480464 Mitomycin results in decreased expression of DNMT1 protein CTD PMID:27032448 Dnmt1 Rat mono(2-ethylhexyl) phthalate increases expression ISO Dnmt1 (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of DNMT1 mRNA CTD PMID:22401849 Dnmt1 Rat mono(2-ethylhexyl) phthalate multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of DNMT1 mRNA and [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of DNMT1 mRNA CTD PMID:35861251 Dnmt1 Rat monobenzyl phthalate multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of DNMT1 mRNA and [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of DNMT1 mRNA CTD PMID:35861251 Dnmt1 Rat Monobutylphthalate multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of DNMT1 mRNA and [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of DNMT1 mRNA CTD PMID:35861251 Dnmt1 Rat monoethyl phthalate multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] affects the expression of DNMT1 mRNA and [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with monobutyl phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of DNMT1 mRNA CTD PMID:35861251 Dnmt1 Rat morphine increases expression ISO Dnmt1 (Mus musculus) 6480464 Morphine results in increased expression of DNMT1 mRNA CTD PMID:33891991 Dnmt1 Rat myricetin multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [myricetin co-treated with COMT protein] results in decreased activity of DNMT1 protein CTD PMID:16037419 Dnmt1 Rat myricetin decreases activity ISO DNMT1 (Homo sapiens) 6480464 myricetin results in decreased activity of DNMT1 protein CTD PMID:16037419 Dnmt1 Rat N(4)-hydroxycytidine decreases expression ISO Dnmt1 (Mus musculus) 6480464 N(4)-hydroxycytidine results in decreased expression of DNMT1 mRNA CTD PMID:37748715 Dnmt1 Rat N-acetyl-L-cysteine multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Acetylcysteine co-treated with Hydrogen Peroxide] results in increased expression of DNMT1 mRNA more ... CTD PMID:29854080 more ... Dnmt1 Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO DNMT1 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Benzo(a)pyrene results in increased degradation of DNMT1 protein] CTD PMID:21150308 Dnmt1 Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO Dnmt1 (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of DNMT1 protein] CTD PMID:23395981 Dnmt1 Rat N-ethyl-N-nitrosourea increases expression ISO Dnmt1 (Mus musculus) 6480464 Ethylnitrosourea results in increased expression of DNMT1 CTD PMID:21154115 Dnmt1 Rat N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Methylcholanthrene] affects the expression of and affects the localization of DNMT1 protein CTD PMID:21163286 Dnmt1 Rat N-nitrosodiethylamine increases expression ISO Dnmt1 (Mus musculus) 6480464 Diethylnitrosamine results in increased expression of DNMT1 mRNA CTD PMID:17854601 Dnmt1 Rat N-nitrosodiethylamine decreases expression ISO Dnmt1 (Mus musculus) 6480464 Diethylnitrosamine results in decreased expression of DNMT1 mRNA CTD PMID:19996281 Dnmt1 Rat N-nitrosodiethylamine multiple interactions ISO Dnmt1 (Mus musculus) 6480464 AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of DNMT1 mRNA] and RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DNMT1 mRNA] CTD PMID:17854601 and PMID:19996281 Dnmt1 Rat nickel atom increases expression ISO DNMT1 (Homo sapiens) 6480464 Nickel results in increased expression of DNMT1 mRNA CTD PMID:25583101 Dnmt1 Rat nicotinamide multiple interactions ISO Dnmt1 (Mus musculus) 6480464 Niacinamide affects the reaction [9 more ... CTD PMID:24792773 Dnmt1 Rat nicotine multiple interactions EXP 6480464 Dihydro-beta-Erythroidine analog inhibits the reaction [Nicotine results in decreased expression of DNMT1 mRNA] CTD PMID:28555334 Dnmt1 Rat nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of DNMT1 mRNA CTD PMID:28555334 Dnmt1 Rat okadaic acid multiple interactions ISO DNMT1 (Homo sapiens) 6480464 Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein] CTD PMID:23775084 Dnmt1 Rat oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of DNMT1 mRNA CTD PMID:25729387 Dnmt1 Rat ozone affects response to substance ISO DNMT1 (Homo sapiens) 6480464 DNMT1 gene polymorphism affects the susceptibility to Ozone CTD PMID:27219456 Dnmt1 Rat ozone multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in decreased expression of and results in increased oxidation of DNMT1 mRNA CTD PMID:32845096 Dnmt1 Rat ozone multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of DNMT1 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of DNMT1 mRNA CTD PMID:34911549 Dnmt1 Rat paracetamol affects expression ISO Dnmt1 (Mus musculus) 6480464 Acetaminophen affects the expression of DNMT1 mRNA CTD PMID:17562736 Dnmt1 Rat paracetamol increases expression ISO DNMT1 (Homo sapiens) 6480464 Acetaminophen results in increased expression of DNMT1 mRNA CTD PMID:22230336 Dnmt1 Rat paraquat decreases expression ISO DNMT1 (Homo sapiens) 6480464 Paraquat results in decreased expression of DNMT1 mRNA and Paraquat results in decreased expression of DNMT1 protein CTD PMID:31189234 Dnmt1 Rat pelargonidin decreases expression ISO Dnmt1 (Mus musculus) 6480464 pelargonidin results in decreased expression of DNMT1 protein CTD PMID:31181187 Dnmt1 Rat pentachlorophenol increases expression ISO Dnmt1 (Mus musculus) 6480464 Pentachlorophenol results in increased expression of DNMT1 mRNA CTD PMID:23892564 Dnmt1 Rat perfluorooctane-1-sulfonic acid decreases expression ISO DNMT1 (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in decreased expression of DNMT1 mRNA and perfluorooctane sulfonic acid results in decreased expression of DNMT1 protein CTD PMID:31508952 Dnmt1 Rat perfluorooctanoic acid decreases expression ISO DNMT1 (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of DNMT1 protein CTD PMID:26879310 Dnmt1 Rat perfluorooctanoic acid increases expression ISO Dnmt1 (Mus musculus) 6480464 perfluorooctanoic acid results in increased expression of DNMT1 mRNA CTD PMID:32320774 Dnmt1 Rat perfluorooctanoic acid multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with perfluorooctanoic acid] results in increased expression of DNMT1 mRNA CTD PMID:29094436 Dnmt1 Rat phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of DNMT1 mRNA and Phenobarbital results in increased expression of DNMT1 protein CTD PMID:25247799 and PMID:30141584 Dnmt1 Rat phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of DNMT1 protein CTD PMID:28495587 Dnmt1 Rat phenobarbital affects expression ISO Dnmt1 (Mus musculus) 6480464 Phenobarbital affects the expression of DNMT1 mRNA CTD PMID:19482888 and PMID:23091169 Dnmt1 Rat PhIP increases expression ISO Dnmt1 (Mus musculus) 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of DNMT1 protein CTD PMID:22581815 Dnmt1 Rat PhIP multiple interactions EXP 6480464 [2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine co-treated with Dietary Fats] results in increased expression of DNMT1 mRNA CTD PMID:12097258 Dnmt1 Rat phorbol 13-acetate 12-myristate multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein more ... CTD PMID:23775084 Dnmt1 Rat piperonyl butoxide increases expression EXP 6480464 Piperonyl Butoxide results in increased expression of DNMT1 mRNA CTD PMID:22484513 Dnmt1 Rat pirinixic acid decreases expression ISO Dnmt1 (Mus musculus) 6480464 pirinixic acid results in decreased expression of DNMT1 mRNA CTD PMID:17426115 Dnmt1 Rat pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of DNMT1 protein CTD PMID:18639561 Dnmt1 Rat piroxicam increases expression ISO DNMT1 (Homo sapiens) 6480464 Piroxicam results in increased expression of DNMT1 mRNA CTD PMID:21858171 Dnmt1 Rat poly(I:C) multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Arsenicals co-treated with Poly I-C co-treated with Alitretinoin] results in increased expression of DNMT1 mRNA and [Arsenicals co-treated with Poly I-C] results in increased expression of DNMT1 mRNA CTD PMID:34303791 Dnmt1 Rat procyanidin B2 increases expression ISO DNMT1 (Homo sapiens) 6480464 procyanidin B2 results in increased expression of DNMT1 mRNA CTD PMID:25839702 Dnmt1 Rat pterostilbene multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [resveratrol co-treated with pterostilbene] results in decreased expression of DNMT1 mRNA CTD PMID:26459286 Dnmt1 Rat Pyridostigmine bromide multiple interactions ISO DNMT1 (Homo sapiens) 6480464 SOD2 protein SNP inhibits the reaction [Pyridostigmine Bromide results in decreased expression of DNMT1 mRNA] CTD PMID:31175926 Dnmt1 Rat Pyridostigmine bromide decreases expression ISO DNMT1 (Homo sapiens) 6480464 Pyridostigmine Bromide results in decreased expression of DNMT1 mRNA CTD PMID:31175926 Dnmt1 Rat quercetin decreases expression ISO DNMT1 (Homo sapiens) 6480464 Quercetin results in decreased expression of DNMT1 mRNA CTD PMID:20596804 Dnmt1 Rat quercetin increases activity ISO DNMT1 (Homo sapiens) 6480464 Quercetin results in increased activity of DNMT1 protein CTD PMID:27132804 Dnmt1 Rat quercetin increases expression ISO DNMT1 (Homo sapiens) 6480464 Quercetin results in increased expression of DNMT1 mRNA CTD PMID:21632981 Dnmt1 Rat quercetin multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Quercetin co-treated with COMT protein] results in decreased activity of DNMT1 protein more ... CTD PMID:16037419 and PMID:27132804 Dnmt1 Rat resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [DNMT1 protein binds to BRCA1 promoter]] CTD PMID:24136580 Dnmt1 Rat resveratrol decreases expression ISO DNMT1 (Homo sapiens) 6480464 resveratrol results in decreased expression of DNMT1 mRNA and resveratrol results in decreased expression of DNMT1 protein CTD PMID:21801466 more ... Dnmt1 Rat resveratrol decreases expression ISO Dnmt1 (Mus musculus) 6480464 resveratrol results in decreased expression of DNMT1 protein CTD PMID:25505154 Dnmt1 Rat resveratrol multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Coumestrol co-treated with Resveratrol] results in increased expression of DNMT1 mRNA more ... CTD PMID:19167446 more ... Dnmt1 Rat rosmarinic acid decreases expression ISO DNMT1 (Homo sapiens) 6480464 Rosmarinic Acid results in decreased expression of DNMT1 protein CTD PMID:21078381 Dnmt1 Rat rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of DNMT1 protein CTD PMID:35544339 Dnmt1 Rat S-adenosyl-L-homocysteine decreases activity ISO DNMT1 (Homo sapiens) 6480464 S-Adenosylhomocysteine results in decreased activity of DNMT1 protein CTD PMID:16037419 Dnmt1 Rat S-adenosyl-L-homocysteine multiple interactions ISO Dnmt1 (Mus musculus) 6480464 S-Adenosylhomocysteine inhibits the reaction [DNMT1 protein binds to OGG1 promoter] CTD PMID:22064374 Dnmt1 Rat S-adenosyl-L-homocysteine decreases activity ISO Dnmt1 (Mus musculus) 6480464 S-Adenosylhomocysteine results in decreased activity of DNMT1 protein CTD PMID:22064374 Dnmt1 Rat S-adenosyl-L-methioninate multiple interactions ISO DNMT1 (Homo sapiens) 6480464 S-Adenosylmethionine inhibits the reaction [arsenic trioxide inhibits the reaction [DNMT1 protein binds to ESR1 promoter]] and S-Adenosylmethionine inhibits the reaction [arsenic trioxide results in decreased expression of DNMT1 protein] CTD PMID:22558281 Dnmt1 Rat S-adenosyl-L-methionine multiple interactions ISO DNMT1 (Homo sapiens) 6480464 S-Adenosylmethionine inhibits the reaction [arsenic trioxide inhibits the reaction [DNMT1 protein binds to ESR1 promoter]] and S-Adenosylmethionine inhibits the reaction [arsenic trioxide results in decreased expression of DNMT1 protein] CTD PMID:22558281 Dnmt1 Rat SB 431542 multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of DNMT1 protein CTD PMID:37664457 Dnmt1 Rat selenium atom affects activity EXP 6480464 Selenium affects the activity of DNMT1 protein CTD PMID:16632891 Dnmt1 Rat silicon dioxide multiple interactions ISO DNMT1 (Homo sapiens) 6480464 DNMT1 protein promotes the reaction [Silicon Dioxide results in increased methylation of PARP1 promoter] CTD PMID:22265868 Dnmt1 Rat sinefungin decreases activity ISO DNMT1 (Homo sapiens) 6480464 sinefungin results in decreased activity of DNMT1 protein CTD PMID:23671287 Dnmt1 Rat sirolimus multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [fulvestrant co-treated with Sirolimus] results in decreased expression of DNMT1 mRNA CTD PMID:19016759 Dnmt1 Rat sodium arsenite multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Decitabine co-treated with sodium arsenite] results in decreased expression of DNMT1 protein more ... CTD PMID:22952798 more ... Dnmt1 Rat sodium arsenite increases expression ISO DNMT1 (Homo sapiens) 6480464 sodium arsenite results in increased expression of DNMT1 mRNA and sodium arsenite results in increased expression of DNMT1 protein CTD PMID:31150806 more ... Dnmt1 Rat sodium arsenite multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency co-treated with sodium arsenite] results in decreased expression of DNMT1 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of DNMT1 protein CTD PMID:20978746 and PMID:34952004 Dnmt1 Rat sodium arsenite affects expression ISO Dnmt1 (Mus musculus) 6480464 sodium arsenite affects the expression of DNMT1 mRNA CTD PMID:17558810 Dnmt1 Rat sodium arsenite increases expression ISO Dnmt1 (Mus musculus) 6480464 sodium arsenite results in increased expression of DNMT1 mRNA CTD PMID:19822182 Dnmt1 Rat sodium arsenite decreases expression ISO DNMT1 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of DNMT1 mRNA and sodium arsenite results in decreased expression of DNMT1 protein CTD PMID:17107663 more ... Dnmt1 Rat sodium dichromate multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [sodium bichromate co-treated with isorhapontigenin] results in decreased expression of DNMT1 protein CTD PMID:37619952 Dnmt1 Rat sodium fluoride increases expression ISO Dnmt1 (Mus musculus) 6480464 Sodium Fluoride results in increased expression of DNMT1 mRNA CTD PMID:27862939 Dnmt1 Rat Soman decreases expression EXP 6480464 Soman results in decreased expression of DNMT1 mRNA CTD PMID:19281266 Dnmt1 Rat streptozocin multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT1 mRNA more ... CTD PMID:28422052 and PMID:29127188 Dnmt1 Rat streptozocin multiple interactions EXP 6480464 [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 mRNA] more ... CTD PMID:36547818 Dnmt1 Rat streptozocin decreases expression ISO Dnmt1 (Mus musculus) 6480464 Streptozocin results in decreased expression of DNMT1 mRNA CTD PMID:28422052 Dnmt1 Rat sucrose multiple interactions ISO Dnmt1 (Mus musculus) 6480464 2 more ... CTD PMID:37516258 Dnmt1 Rat sulforaphane decreases expression ISO DNMT1 (Homo sapiens) 6480464 sulforaphane results in decreased expression of DNMT1 mRNA CTD PMID:24466240 Dnmt1 Rat sulforaphane multiple interactions ISO DNMT1 (Homo sapiens) 6480464 sulforaphane inhibits the reaction [Estradiol results in increased expression of DNMT1 mRNA] and sulforaphane inhibits the reaction [Genistein results in increased expression of DNMT1 mRNA] CTD PMID:30684530 Dnmt1 Rat T-2 toxin increases expression EXP 6480464 T-2 Toxin results in increased expression of DNMT1 mRNA and T-2 Toxin results in increased expression of DNMT1 protein CTD PMID:31279042 Dnmt1 Rat tamoxifen multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [arsenic trioxide co-treated with Tamoxifen] results in decreased expression of DNMT1 mRNA and [arsenic trioxide co-treated with Tamoxifen] results in decreased expression of DNMT1 protein CTD PMID:23159075 Dnmt1 Rat tangeretin decreases expression ISO Dnmt1 (Mus musculus) 6480464 tangeretin metabolite results in decreased expression of DNMT1 protein and tangeretin results in decreased expression of DNMT1 protein CTD PMID:37517432 Dnmt1 Rat temozolomide increases expression ISO DNMT1 (Homo sapiens) 6480464 Temozolomide results in increased expression of DNMT1 mRNA CTD PMID:31758290 Dnmt1 Rat testosterone multiple interactions ISO DNMT1 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of DNMT1 mRNA CTD PMID:21592394 Dnmt1 Rat testosterone multiple interactions EXP 6480464 [Testosterone co-treated with vinclozolin] results in increased expression of DNMT1 mRNA and Testosterone inhibits the reaction [vinclozolin results in decreased expression of DNMT1 mRNA] CTD PMID:20056826 Dnmt1 Rat testosterone decreases expression ISO DNMT1 (Homo sapiens) 6480464 Testosterone results in decreased expression of DNMT1 mRNA CTD PMID:21592394 Dnmt1 Rat tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of DNMT1 mRNA and Carbon Tetrachloride results in increased expression of DNMT1 protein CTD PMID:22841775 more ... Dnmt1 Rat tetrachloromethane multiple interactions ISO Dnmt1 (Mus musculus) 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of DNMT1 mRNA CTD PMID:30517762 Dnmt1 Rat tetrachloromethane increases expression ISO Dnmt1 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of DNMT1 mRNA CTD PMID:27339419 and PMID:31919559 Dnmt1 Rat thapsigargin increases expression ISO Dnmt1 (Mus musculus) 6480464 Thapsigargin results in increased expression of DNMT1 protein CTD PMID:24648495 Dnmt1 Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of DNMT1 mRNA CTD PMID:34492290 Dnmt1 Rat titanium dioxide decreases methylation ISO Dnmt1 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of DNMT1 promoter CTD PMID:35295148 Dnmt1 Rat topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of DNMT1 mRNA CTD PMID:25729387 Dnmt1 Rat topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of DNMT1 mRNA CTD PMID:25729387 Dnmt1 Rat Tributyltin oxide increases phosphorylation ISO Dnmt1 (Mus musculus) 6480464 bis(tri-n-butyltin)oxide results in increased phosphorylation of DNMT1 protein CTD PMID:22174045 Dnmt1 Rat trichloroethene increases expression ISO Dnmt1 (Mus musculus) 6480464 Trichloroethylene results in increased expression of DNMT1 mRNA and Trichloroethylene results in increased expression of DNMT1 protein CTD PMID:22407948 and PMID:25549359 Dnmt1 Rat triclosan decreases expression ISO DNMT1 (Homo sapiens) 6480464 Triclosan results in decreased expression of DNMT1 mRNA and Triclosan results in decreased expression of DNMT1 protein CTD PMID:26970259 Dnmt1 Rat trimellitic anhydride increases expression ISO Dnmt1 (Mus musculus) 6480464 trimellitic anhydride results in increased expression of DNMT1 mRNA CTD PMID:19042947 Dnmt1 Rat trimethylarsine oxide decreases expression EXP 6480464 trimethylarsine oxide results in decreased expression of DNMT1 mRNA CTD PMID:17481689 Dnmt1 Rat triphenyl phosphate affects expression ISO DNMT1 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of DNMT1 mRNA CTD PMID:37042841 Dnmt1 Rat triptonide affects expression ISO Dnmt1 (Mus musculus) 6480464 triptonide affects the expression of DNMT1 mRNA CTD PMID:33045310 Dnmt1 Rat troglitazone decreases expression ISO DNMT1 (Homo sapiens) 6480464 troglitazone results in decreased expression of DNMT1 mRNA CTD PMID:19140230 Dnmt1 Rat troglitazone decreases expression ISO Dnmt1 (Mus musculus) 6480464 troglitazone results in decreased expression of DNMT1 mRNA CTD PMID:28973697 Dnmt1 Rat trovafloxacin decreases expression ISO Dnmt1 (Mus musculus) 6480464 trovafloxacin results in decreased expression of DNMT1 mRNA CTD PMID:35537566 Dnmt1 Rat tungsten decreases expression ISO Dnmt1 (Mus musculus) 6480464 Tungsten results in decreased expression of DNMT1 mRNA CTD PMID:30912803 Dnmt1 Rat uranium atom increases expression EXP 6480464 Uranium results in increased expression of DNMT1 mRNA CTD PMID:29024790 Dnmt1 Rat valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of DNMT1 mRNA CTD PMID:29427782 Dnmt1 Rat vancomycin decreases expression ISO Dnmt1 (Mus musculus) 6480464 Vancomycin results in decreased expression of DNMT1 mRNA CTD PMID:18930951 Dnmt1 Rat vinclozolin multiple interactions EXP 6480464 [Testosterone co-treated with vinclozolin] results in increased expression of DNMT1 mRNA and Testosterone inhibits the reaction [vinclozolin results in decreased expression of DNMT1 mRNA] CTD PMID:20056826 Dnmt1 Rat vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of DNMT1 mRNA CTD PMID:23034163 Dnmt1 Rat vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of DNMT1 mRNA and vinclozolin results in decreased expression of DNMT1 protein CTD PMID:18042343 and PMID:20056826 Dnmt1 Rat vitamin E increases expression ISO DNMT1 (Homo sapiens) 6480464 Vitamin E results in increased expression of DNMT1 mRNA CTD PMID:29854080 Dnmt1 Rat withaferin A decreases expression ISO DNMT1 (Homo sapiens) 6480464 withaferin A results in decreased expression of DNMT1 mRNA and withaferin A results in decreased expression of DNMT1 protein CTD PMID:23593078 Dnmt1 Rat zearalenone increases expression ISO DNMT1 (Homo sapiens) 6480464 Zearalenone results in increased expression of DNMT1 mRNA CTD PMID:32119988