Gene: Optn (optineurin) Rattus norvegicus
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Symbol: Optn
Name: optineurin
Description: ENCODES a protein that exhibits identical protein binding; TFIIIA-class transcription factor binding; ubiquitin binding; INVOLVED IN cellular response to hydrogen peroxide; cellular response to L-glutamate; cellular response to nerve growth factor stimulus; PARTICIPATES IN mitochondrial autophagy pathway; ASSOCIATED WITH bladder neck obstruction; Dental Pulp Exposure; Parkinson's disease; FOUND IN axon; cytoplasm; cytoplasmic vesicle; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 14.7K-interacting protein 2; FIP-2-like protein; Fip2
Orthologs:
Homo sapiens (human) : OPTN (optineurin)  HGNC  Alliance
Mus musculus (house mouse) : Optn (optineurin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Optn (optineurin)
Pan paniscus (bonobo/pygmy chimpanzee) : OPTN (optineurin)
Canis lupus familiaris (dog) : OPTN (optineurin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101956249 (optineurin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01777,167,700 - 77,218,374 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01778,833,443 - 78,884,464 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41784,298,122 - 84,348,330 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11784,317,800 - 84,359,163 (+)NCBI
Celera1772,649,264 - 72,699,727 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Optn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 628886
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-01-08
Status: ACTIVE