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Rat Genetic Models

Gene Symbol	Gene	No. of Models	Background Strain	Strain Symbol	Aliases	Method	Availability	Origination
Has2	hyaluronan synthase 2	1	BN/NHsdMcwi	BN-Has2^m1Mcwi		ENU	Unknown	PGA
Myo9a	myosin IXA	1	F344/NCrl	F344-Myo9a^{Tn(sb-T2/Bart3)2.186Mcwi}		Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Sbf1	SET binding factor 1	1		SHR-Sbf1^m1Ipcv			Unknown	Institute of Biology and Medical Genetics, Charles University, Prague
Tmem67	transmembrane protein 67	3	No Background Strains Assigned
				Wpk			Unknown
				Wpk ^+/-	TMEM67+/−		Unknown
				Wpk ^-/-	TMEM67−/−		Unknown
Spp1	secreted phosphoprotein 1	4	SHRSP/A3NCrl, SS/JrHsdMcwi
			SHRSP/A3NCrl	SHRSP-Spp1^em1Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2017-01-26)	MCW Gene Editing Rat Resource Center; Contact MCW rat distribution at mcwcustomrats@mcw.edu
			SS/JrHsdMcwi	SS-Spp1^em3Mcwi	Strain00438	CRISPR/Cas9	Cryopreserved Sperm (as of 2021-11-03)	MCW Gene Editing Rat Resource Center; Contact MCW rat distribution at mcwcustomrats@mcw.edu
			SS/JrHsdMcwi	SS-Spp1^em4Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2021-11-03)	MCW Gene Editing Rat Resource Center; Contact MCW rat distribution at mcwcustomrats@mcw.edu
			SHRSP/A3NCrl	SHRSP-Spp1^em2Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2018-10-01)	MCW Gene Editing Rat Resource Center; Contact MCW rat distribution at mcwcustomrats@mcw.edu
Slc30a8	solute carrier family 30 member 8	2	SS/JrHsdMcwi
			SS/JrHsdMcwi	SS-Slc30a8^em2Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Slc30a8^em1Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
Aif1	allograft inflammatory factor 1	1		SD-Aif1^tm(EGFP)Apps/Mmmc			Unknown	Department of Pharmacology, University of Maryland School of Medicine, Baltimore, Maryland 21201
Fgf5	fibroblast growth factor 5	2	SS/JrHsdMcwi
			SS/JrHsdMcwi	SS-Fgf5^em1Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Fgf5^em5Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
Trpa1	transient receptor potential cation channel, subfamily A, member 1	2	Crl:WI
				SD-Trpa1^em1Gne		CRISPR/Cas9	Unknown	Department of Neuroscience, Genentech, 1 DNA Way, South San Francisco, CA 94080 USA
			Crl:WI	W-Trpa1^em1Kcrd	NBRP Rat No: 0903 ; TRPA1 KO rat	ZFN	Cryopreserved Embryo (as of 2020-09-17)	National BioResource Project for the Rat in Japan
Flna	filamin A	1	Crl:SD	SD-Flna^em1Ang			Unknown	The Transgenic Rats and ImmunoPhenomic (TRIP) facility in Nantes (France).
Rasgrp3	RAS guanyl releasing protein 3	2	SS/JrHsdMcwi
			SS/JrHsdMcwi	SS-Rasgrp3^em3Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
			SS/JrHsdMcwi	SS-Rasgrp3^em1Mcwi		ZFN	Cryopreserved Sperm (as of 2017-01-26)	PhysGen Knockouts
Tlr4	toll-like receptor 4	3	FHH/EurMcwi, BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi
				WI-Tlr4^em1Geh			Unknown	University of Pittsburgh, Rat Resource and Research Center
			FHH/EurMcwi	FHH-Tlr4^m1Mcwi		ENU	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
			BBDR.BBDP-(D4Mit6-D4Mit7)/RhwMcwi	BBDR.BBDP-(D4Mit6-D4Mit7)-Tlr4^em5Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2019-03-25)	MCW Gene Editing Rat Resource Center; Contact MCW rat distribution at mcwcustomrats@mcw.edu
Mir29b1	microRNA 29b-1	1	SS-Chr 13^BN/Mcwi	SS-Chr 13^BN-Mir29b^em1Mcwi	Mir29b-1/a - / -	TALEN	Live Animals; Cryopreserved Sperm (as of 2021-11-03)	PhysGen Knockouts
RGD1563503	similar to ribosomal protein L6	1	F344/NCrl	F344-RGD1563503^{Tn(sb-T2/Bart3)2.313Mcwi}		Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Klf4	KLF transcription factor 4	3	SS/JrHsdMcwi
			SS/JrHsdMcwi	SS-Klf4^m3Mcwi		ENU	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
			SS/JrHsdMcwi	SS-Klf4^m1Mcwi		ENU	Unknown	PGA
			SS/JrHsdMcwi	SS-Klf4^m2Mcwi		ENU	Unknown	PGA
Patj	PATJ, crumbs cell polarity complex component	1	F344/NCrl	F344-Patj^{Tn(sb-T2/Bart3)2.343Mcwi}	F344-InadlTn(sb-T2/Bart3)2.343Mcwi	Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Nkx3-1	NK3 homeobox 1	2	No Background Strains Assigned
				SD-Nkx3-1^em1Pjhak-/-		TALEN	Unknown	Department of Laboratory Animal Medicine College of Veterinary Medicine Seoul National University
				SD-Nkx3-1^em1Pjhak+/-		TALEN	Unknown	Department of Laboratory Animal Medicine College of Veterinary Medicine Seoul National University
Gng12	G protein subunit gamma 12	1	F344/NCrl	F344-Gng12^{Tn(sb-T2/Bart3)2.320Mcwi}		Sleeping Beauty	Cryopreserved Sperm (as of 2017-01-26)	PhysGen
Gh1	growth hormone 1	1		SDR/Slc	NBRP Rat No: 0151		Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-05-04)	National BioResource Project for the Rat in Japan, Rat Resource and Research Center
Slc9a6	solute carrier family 9 member A6	1	Hsd:SD	SD-Slc9a6 ^em1Moro	NHE6-null rat	CRISPR/Cas9	Unknown	Organization: Brown University 70 Ship Street, Box G-E4 Providence RI 02912 USA
Chrna4	cholinergic receptor nicotinic alpha 4 subunit	2	LEW/Crl, LEW/NCrl
			LEW/Crl	LEW-Chrna4^em4Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2018-11-26)	MCW Gene Editing Rat Resource Center; Contact MCW rat distribution at mcwcustomrats@mcw.edu
			LEW/NCrl	LEW-Chrna4^em3Mcwi		CRISPR/Cas9	Cryopreserved Sperm (as of 2018-11-26)	MCW Gene Editing Rat Resource Center; Contact MCW rat distribution at mcwcustomrats@mcw.edu
Crh	corticotropin releasing hormone	1		SD-Crh^em1Ionsz			Unknown	Institute of Neuroscience, Chinese Academy of Sciences

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