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Strain: WKY-Slc39a12em77Tja

Symbol: WKY-Slc39a12em77Tja
Strain: WKY-Slc39a12em77
Substrain: Tja
RGD ID: 10401843
Citation ID: RRID:RGD_10401843
Ontology ID: RS:0004053
Alleles: Slc39a12em77Tja
Previously known as: WKY-Slc39a12em77Tja
Type: mutant
Source: MRC Clinical Centre, London, UK
Origin: This strain was produced by injecting ZFNs targeted sequence into WKY/Cruk rat embryos. The resulting mutation 77 has a stop codon, 15 amino acids from the ZFN-binding site, that resulted in a 490 amino acids (54 kDa) truncated protein, 198 amino acids smaller than the WT protein.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21777,353,761 - 77,440,381RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01781,455,731 - 81,541,742RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01783,202,775 - 83,288,616RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41788,525,527 - 88,605,947RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. RGD Strain RSO annotation pipeline RGD Automated Pipelines
2. The zinc transporter ZIP12 regulates the pulmonary vascular response to chronic hypoxia. Zhao L, etal., Nature. 2015 Aug 20;524(7565):356-60. doi: 10.1038/nature14620. Epub 2015 Aug 10.

Region


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-16 WKY-Slc39a12em77Tja    WKY-Slc39a12em77Tja    Symbol updated 68687 APPROVED
2016-03-16 WKY-Slc39a12em77Tja    WKY-Slc39a12em77Tja    Name updated 68913 APPROVED
2016-03-16 WKY-Slc39a12em77Tja    WKY-Slc39a12em77Tja    Symbol updated 68687 APPROVED
2016-03-16 WKY-Slc39a12em77Tja    WKY-Slc39a12em77Tja    Name updated 68913 APPROVED