Npy (neuropeptide Y) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Npy (neuropeptide Y) Rattus norvegicus
Analyze
Symbol: Npy
Name: neuropeptide Y
RGD ID: 3197
Description: Exhibits neuropeptide Y receptor binding activity. Involved in several processes, including adult feeding behavior; positive regulation of appetite; and positive regulation of nitrogen compound metabolic process. Localizes to several cellular components, including neuronal dense core vesicle; perikaryon; and perinuclear region of cytoplasm. Used to study alcohol use disorder; childhood absence epilepsy; hypertension; and mental depression. Biomarker of several diseases, including brain disease (multiple); median neuropathy; mental depression; neurodegenerative disease (multiple); and obesity. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; alcohol use disorder; artery disease (multiple); epilepsy (multiple); and type 2 diabetes mellitus. Orthologous to human NPY (neuropeptide Y); PARTICIPATES IN neuropeptide Y metabolic pathway; INTERACTS WITH (+)-pilocarpine; (S)-amphetamine; (S)-nicotine.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: LOC100912228; NPY02; pro-neuropeptide Y; pro-neuropeptide Y-like; RATNPY; RATNPY02
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Npyem6Sage  
Genetic Models: NP/Iusm-Npyem6Sage NP/Iusm-Npyem6Sage-/- NP/Iusm-Npyem6Sage+/-
Is Marker For: Strains:   SHR.BN-(Il6-Npy)   P   NP   BB.SHR-(D4Mit6-Spr)/K   NP.P-(D4Rat119-D4Rat55)/Iusm  
QTLs:   Bp21   Bp135  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2478,881,294 - 78,888,495 (+)NCBI
Rnor_6.0 Ensembl479,557,854 - 79,565,097 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl479,573,998 - 79,581,208 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0479,557,856 - 79,565,059 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04144,233,753 - 144,240,956 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4478,038,013 - 78,045,187 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1478,314,142 - 78,321,317 (+)NCBI
Celera473,795,148 - 73,802,371 (+)NCBICelera
RH 3.4 Map4507.8RGD
RH 3.4 Map4508.6RGD
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (EXP,ISO)
(R)-noradrenaline  (ISO)
(S)-amphetamine  (EXP)
(S)-nicotine  (EXP)
1,2-dichloroethane  (ISO)
1,3,5-trinitro-1,3,5-triazinane  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-deoxy-D-glucose  (EXP)
3,4-methylenedioxymethamphetamine  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acarbose  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
AM-251  (EXP)
amitriptyline  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP,ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
aspartame  (EXP)
ATP  (ISO)
Aurothioglucose  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bexarotene  (EXP)
bezafibrate  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bucladesine  (EXP)
C60 fullerene  (EXP)
cadmium atom  (ISO)
capsaicin  (EXP)
capsazepine  (ISO)
carbachol  (ISO)
carbon nanotube  (ISO)
chlorisondamine  (EXP)
chlorpyrifos  (EXP,ISO)
choline  (ISO)
clofibrate  (ISO)
clonidine  (EXP)
clonidine (amino form)  (EXP)
clonidine (imino form)  (EXP)
clozapine  (EXP)
cocaine  (EXP)
corticosterone  (EXP)
cortisol  (ISO)
cytarabine  (ISO)
D-glucose  (EXP)
deoxynivalenol  (EXP)
dexamethasone  (EXP)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dieldrin  (EXP)
diprotium oxide  (EXP)
dorsomorphin  (ISO)
entinostat  (ISO)
enzyme inhibitor  (EXP)
ethanol  (EXP,ISO)
fluoxetine  (EXP,ISO)
folic acid  (ISO)
fructose  (EXP)
furan  (EXP)
gentamycin  (EXP)
glucose  (EXP)
glycidol  (EXP)
guanethidine  (EXP,ISO)
haloperidol  (EXP)
Hexamethonium  (EXP)
kainic acid  (EXP,ISO)
ketamine  (ISO)
L-methionine  (ISO)
limonene  (EXP,ISO)
linalool  (EXP,ISO)
lithium atom  (EXP)
lithium hydride  (EXP)
mercury dibromide  (ISO)
metformin  (ISO)
methamphetamine  (EXP,ISO)
methylmercury chloride  (ISO)
monosodium L-glutamate  (EXP,ISO)
morphine  (ISO)
nickel atom  (EXP)
nicotine  (EXP)
nitroglycerin  (EXP)
olanzapine  (EXP,ISO)
orlistat  (ISO)
orphenadrine  (EXP)
oxaliplatin  (EXP)
oxidopamine  (EXP)
Oxotremorine  (EXP)
ozone  (EXP)
paclitaxel  (EXP)
panobinostat  (ISO)
paracetamol  (ISO)
paricalcitol  (ISO)
pentobarbital  (ISO)
phenacetin  (EXP)
phenformin  (EXP)
phenylephrine  (ISO)
phenylhydrazine  (EXP)
phenylmercury acetate  (ISO)
phenylpropanolamine  (EXP)
phorbol 13-acetate 12-myristate  (EXP,ISO)
pioglitazone  (ISO)
pirinixic acid  (EXP,ISO)
potassium atom  (EXP,ISO)
potassium chloride  (EXP)
prazosin  (EXP)
progesterone  (EXP,ISO)
propofol  (EXP)
quinpirole  (ISO)
reserpine  (EXP)
rotenone  (EXP)
ruthenium red  (ISO)
SB 431542  (ISO)
SCH 23390  (EXP)
silicon dioxide  (ISO)
SKF 38393  (ISO)
Soman  (EXP)
streptozocin  (EXP)
succimer  (ISO)
terbutaline  (ISO)
Tesaglitazar  (EXP)
tetrachloromethane  (ISO)
tetrodotoxin  (EXP)
thiopental  (EXP)
titanium dioxide  (ISO)
topiramate  (EXP)
topotecan  (EXP)
tribromoethanol  (ISO)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
trichostatin A  (EXP,ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (EXP)
undecane  (EXP)
valproic acid  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vanadyl sulfate  (EXP)
vancomycin  (ISO)
veratridine  (EXP)
vincaleukoblastine  (EXP)
vinclozolin  (EXP)
vorinostat  (ISO)
water  (EXP)
XL147  (ISO)
yohimbine  (EXP)
zalcitabine  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
1. Alvaro AR, etal., Neurochem Int. 2007 Apr;50(5):757-63. Epub 2007 Feb 8.
2. Bacci A, etal., Proc Natl Acad Sci U S A 2002 Dec 24;99(26):17125-30.
3. Beal MF, etal., J Neurosci. 1991 Jun;11(6):1649-59.
4. Beal MF, etal., Synapse. 1988;2(4):463-7.
5. Bedoui S, etal., J Neuroimmunol 2002 Nov;132(1-2):25-33.
6. Bharat V, etal., Cell Rep. 2017 Nov 21;21(8):2118-2133. doi: 10.1016/j.celrep.2017.10.084.
7. Bjornebekk A, etal., Hippocampus. 2010 Jul;20(7):820-8. doi: 10.1002/hipo.20683.
8. Byku M, etal., Am J Physiol Heart Circ Physiol. 2008 Nov;295(5):H2188-97. doi: 10.1152/ajpheart.00384.2008. Epub 2008 Oct 3.
9. Callanan EY, etal., Am J Physiol Renal Physiol. 2007 Dec;293(6):F1811-7. Epub 2007 Sep 5.
10. Chaffer CL and Morris MJ, Endocrinology 2002 Jan;143(1):191-7.
11. Chance WT, etal., Peptides. 2007 Feb;28(2):295-301. Epub 2007 Jan 17.
12. Croce N, etal., ACS Chem Neurosci. 2012 Apr 18;3(4):312-8. doi: 10.1021/cn200127e. Epub 2012 Jan 30.
13. Currie PJ, etal., Brain Res. 2011 Apr 18;1385:127-34. doi: 10.1016/j.brainres.2011.01.114.
14. Dimitrijevic M, etal., Peptides. 2008 Dec;29(12):2179-87. doi: 10.1016/j.peptides.2008.08.017. Epub 2008 Sep 3.
15. Donner J, etal., Am J Med Genet B Neuropsychiatr Genet. 2012 Apr;159B(3):316-27. doi: 10.1002/ajmg.b.32029. Epub 2012 Feb 10.
16. Duan H, etal., J Surg Res. 2013 Oct;184(2):1006-12. doi: 10.1016/j.jss.2013.03.096. Epub 2013 Apr 18.
17. Dube C, etal., J Mol Neurosci. 2005;25(3):275-84.
18. Elms J, etal., PLoS One. 2013 Sep 9;8(9):e73505. doi: 10.1371/journal.pone.0073505. eCollection 2013.
19. Fekete C, etal., Endocrinology 2002 Dec;143(12):4513-9.
20. Fraley GS and Ritter S, Endocrinology 2003 Jan;144(1):75-83.
21. Ganguly PK Int J Gen Med. 2010 Oct 5;3:321-5. doi: 10.2147/IJGM.S7749.
22. Garcia MC, etal., FASEB J 2003 Aug;17(11):1392-400.
23. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
24. GOA data from the GO Consortium
25. Heilig M, etal., J Psychiatr Res 2004 Mar-Apr;38(2):113-21.
26. Holler J, etal., J Immunol. 2008 Nov 15;181(10):6906-12.
27. Hult Lundh S, etal., Hum Mol Genet. 2013 Sep 1;22(17):3485-97. doi: 10.1093/hmg/ddt203. Epub 2013 May 22.
28. Husum H, etal., Neuropharmacology 2002 May;42(6):798-806.
29. Igura K, etal., Rejuvenation Res. 2011 Aug;14(4):393-403. doi: 10.1089/rej.2010.1129. Epub 2011 May 19.
30. Karvonen MK, etal., Atherosclerosis. 2001 Nov;159(1):145-51.
31. Kawahito Y, etal., J Immunol 1998 Oct 15;161(8):4411-9
32. Kharlamov EA, etal., Brain Res. 2007 Jan 5;1127(1):151-62. Epub 2006 Nov 22.
33. Kloster E, etal., J Mol Med (Berl). 2014 Feb;92(2):177-84.
34. Koide S, etal., Neurosci Lett. 1995 Sep 29;198(2):149-51.
35. Kristensen P, etal., Nature. 1998 May 7;393(6680):72-6.
36. Kuruba R, etal., PLoS One. 2011;6(9):e24493. doi: 10.1371/journal.pone.0024493. Epub 2011 Sep 6.
37. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
38. Lappalainen J, etal., Arch Gen Psychiatry. 2002 Sep;59(9):825-31.
39. Li L, etal., J Cardiovasc Transl Res. 2011 Jun;4(3):351-62. doi: 10.1007/s12265-011-9271-5. Epub 2011 Apr 6.
40. Makarenko IG, etal., Brain Res 2003 Jan 24;961(1):100-8.
41. Malessa R, etal., J Neurol Sci. 1996 Mar;136(1-2):154-8.
42. Melas PA, etal., Peptides. 2012 May;35(1):49-55. doi: 10.1016/j.peptides.2012.02.020. Epub 2012 Mar 3.
43. MGD data from the GO Consortium
44. Michalkiewicz M, etal., Hypertension 2005 Apr;45(4):780-5. Epub 2005 Feb 7.
45. Morris MJ, etal., Eur J Neurosci. 2007 Feb;25(4):1136-43.
46. Morrison CD, etal., Am J Physiol Endocrinol Metab. 2005 Dec;289(6):E1051-7. Epub 2005 Jul 26.
47. Nave H, etal., J Neuroimmunol. 2004 Oct;155(1-2):1-12.
48. NCBI rat LocusLink and RefSeq merged data July 26, 2002
49. Noe F, etal., Brain. 2008 Jun;131(Pt 6):1506-15. doi: 10.1093/brain/awn079. Epub 2008 May 13.
50. Nordman S, etal., Exp Clin Endocrinol Diabetes. 2005 May;113(5):282-7.
51. Pang XH, etal., Int J Colorectal Dis. 2010 Sep;25(9):1047-53. doi: 10.1007/s00384-010-0964-z. Epub 2010 Jun 5.
52. Polgar E, etal., J Comp Neurol. 2011 Apr 15;519(6):1007-23. doi: 10.1002/cne.22570.
53. Proulx K, etal., Endocrinology 2002 Dec;143(12):4683-92.
54. Qiu B, etal., J Genet Genomics. 2016 Jul 20;43(7):421-30. doi: 10.1016/j.jgg.2016.04.010. Epub 2016 Apr 29.
55. Rangani RJ, etal., Peptides. 2012 Feb;33(2):317-28. doi: 10.1016/j.peptides.2012.01.004. Epub 2012 Jan 16.
56. RGD automated data pipeline
57. RGD automated import pipeline for gene-chemical interactions
58. Ross AW, etal., J Neuroendocrinol. 2009 Jul;21(7):610-9. Epub 2009 Apr 13.
59. Schork NJ, etal., Genome Res 1995 Sep;5(2):164-72
60. Sohn EH, etal., Endocrinology 2002 Mar;143(3):954-63.
61. Sorensen AT, etal., Exp Neurol. 2009 Feb;215(2):328-33. doi: 10.1016/j.expneurol.2008.10.015. Epub 2008 Nov 10.
62. Sorensen G, etal., Neuroreport. 2009 Jul 15;20(11):1023-6.
63. Spence JP, etal., Neuroscience 2005;131(4):871-6.
64. Stucchi R, etal., Cell Rep. 2018 Jul 17;24(3):685-700. doi: 10.1016/j.celrep.2018.06.071.
65. Sun SH, etal., Int Immunol 1999 Apr;11(4):529-34
66. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
67. Testa A, etal., J Hypertens. 2010 Aug;28(8):1745-51.
68. Thorsell A, etal., Proc Natl Acad Sci U S A 2000 Nov 7;97(23):12852-7.
69. Tsai YJ, etal., J Neurotrauma. 2009 Sep;26(9):1609-21. doi: 10.1089/neu.2008.0642.
70. Tumer N, etal., Neurosci Lett. 2013 Jun 7;544:62-7. doi: 10.1016/j.neulet.2013.03.042. Epub 2013 Apr 6.
71. Upadhya MA, etal., Neuropeptides. 2009 Aug;43(4):303-14. doi: 10.1016/j.npep.2009.05.003. Epub 2009 Jun 24.
72. Wang C, etal., Horm Metab Res. 2007 Apr;39(4):262-7.
73. Wilder RL, etal., Transplant Proc 1999 May;31(3):1585-8
74. Wirth MJ, etal., Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):3064-9. Epub 2005 Feb 9.
75. Xu ZQ, etal., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2004 Apr;16(4):218-20.
76. Zhao FL, etal., Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11100-5. Epub 2005 Jul 22.
77. Zhiguo W, etal., Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2009 Feb;34(2):93-8.
Additional References at PubMed
PMID:2834371   PMID:3031663   PMID:3031687   PMID:3413293   PMID:8837218   PMID:9067840   PMID:9623984   PMID:9756788   PMID:10698177   PMID:11738809   PMID:11856342   PMID:11897270  
PMID:11914579   PMID:11932938   PMID:12030805   PMID:12069594   PMID:12093484   PMID:12429884   PMID:12450741   PMID:12450742   PMID:12576193   PMID:12590942   PMID:12686755   PMID:12727330  
PMID:12782392   PMID:12786976   PMID:12842868   PMID:12895522   PMID:12902638   PMID:12914981   PMID:12919938   PMID:14551170   PMID:14617575   PMID:15123022   PMID:15127943   PMID:15245875  
PMID:15567472   PMID:15576634   PMID:15582708   PMID:15618885   PMID:15619124   PMID:15652508   PMID:15680466   PMID:15716245   PMID:15716408   PMID:15789763   PMID:15926937   PMID:16051880  
PMID:16087729   PMID:16154634   PMID:16195495   PMID:16198490   PMID:16210372   PMID:16266747   PMID:16336998   PMID:16383008   PMID:16387449   PMID:16426702   PMID:16675522   PMID:16721031  
PMID:16728494   PMID:16867179   PMID:16888209   PMID:16965293   PMID:17011171   PMID:17023531   PMID:17081520   PMID:17154253   PMID:17289093   PMID:17388940   PMID:17400722   PMID:17462823  
PMID:17464216   PMID:17467917   PMID:17684035   PMID:17690163   PMID:17976913   PMID:17989139   PMID:18001323   PMID:18032527   PMID:18094253   PMID:18164503   PMID:18242853   PMID:18308474  
PMID:18323405   PMID:18331583   PMID:18384674   PMID:18389390   PMID:18467436   PMID:18502321   PMID:18504079   PMID:18535107   PMID:18539096   PMID:18544708   PMID:18573184   PMID:18573695  
PMID:18588949   PMID:18598846   PMID:18603306   PMID:18835268   PMID:18937973   PMID:18955035   PMID:19009650   PMID:19017729   PMID:19036961   PMID:19063928   PMID:19095023   PMID:19151514  
PMID:19183337   PMID:19211911   PMID:19229719   PMID:19255506   PMID:19295167   PMID:19383429   PMID:19497417   PMID:19553928   PMID:19559985   PMID:19609086   PMID:19620061   PMID:19671088  
PMID:19817504   PMID:19818818   PMID:19877509   PMID:19879928   PMID:19934016   PMID:19968967   PMID:20012021   PMID:20028355   PMID:20051529   PMID:20179883   PMID:20219870   PMID:20335227  
PMID:20531438   PMID:20610828   PMID:20633633   PMID:20814066   PMID:20817751   PMID:20836657   PMID:20846339   PMID:20945070   PMID:21061149   PMID:21079358   PMID:21162274   PMID:21179736  
PMID:21428728   PMID:21453769   PMID:21473895   PMID:21527271   PMID:21558160   PMID:21589937   PMID:21799827   PMID:21821286   PMID:21855588   PMID:22365383   PMID:22437342   PMID:22461566  
PMID:22474320   PMID:22513398   PMID:22527118   PMID:22643238   PMID:22659471   PMID:22708658   PMID:22832533   PMID:22917777   PMID:22938859   PMID:22964363   PMID:23024812   PMID:23090692  
PMID:23123350   PMID:23271280   PMID:23303411   PMID:23312492   PMID:23313404   PMID:23321476   PMID:23457218   PMID:23526718   PMID:23644054   PMID:23652932   PMID:23680526   PMID:24094067  
PMID:24183962   PMID:24291064   PMID:24308227   PMID:24444822   PMID:24549602   PMID:24582971   PMID:24779394   PMID:24829502   PMID:25011012   PMID:25109664   PMID:25146309   PMID:25197671  
PMID:25241802   PMID:25482245   PMID:25561025   PMID:25635612   PMID:25775546   PMID:25825358   PMID:25952775   PMID:25993471   PMID:26012590   PMID:26047956   PMID:26086271   PMID:26188175  
PMID:26490304   PMID:26514659   PMID:26538454   PMID:26541912   PMID:26561644   PMID:26589184   PMID:26702900   PMID:26707636   PMID:26779765   PMID:27805869   PMID:27855650   PMID:28062253  
PMID:28065829   PMID:28097455   PMID:28438668   PMID:28575455   PMID:28914170   PMID:29425286   PMID:29442423   PMID:29519725   PMID:29777700   PMID:29850786   PMID:30146352   PMID:30227410  
PMID:30950054   PMID:31915051   PMID:32200588  


Genomics

Candidate Gene Status
Npy is a candidate Gene for QTL Eau1
Npy is a candidate Gene for QTL Scwia1
Npy is a candidate Gene for QTL Aia3
Npy is a candidate Gene for QTL Alc18
Npy is a candidate Gene for QTL Bp79
Npy is a candidate Gene for QTL Sach4
Npy is a candidate Gene for QTL Alc16
Npy is a candidate Gene for QTL Alc14
Npy is a candidate Gene for QTL Bw40
Npy is a candidate Gene for QTL Alc21
Npy is a candidate Gene for QTL Alc22
Npy is a candidate Gene for QTL Bp330
Npy is a candidate Gene for QTL Bw126
Comparative Map Data
Npy
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2478,881,294 - 78,888,495 (+)NCBI
Rnor_6.0 Ensembl479,557,854 - 79,565,097 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl479,573,998 - 79,581,208 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0479,557,856 - 79,565,059 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04144,233,753 - 144,240,956 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4478,038,013 - 78,045,187 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1478,314,142 - 78,321,317 (+)NCBI
Celera473,795,148 - 73,802,371 (+)NCBICelera
RH 3.4 Map4507.8RGD
RH 3.4 Map4508.6RGD
Cytogenetic Map4q24NCBI
NPY
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl724,284,188 - 24,291,862 (+)EnsemblGRCh38hg38GRCh38
GRCh38724,284,190 - 24,291,862 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37724,323,809 - 24,331,481 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36724,290,334 - 24,298,002 (+)NCBINCBI36hg18NCBI36
Build 34724,097,048 - 24,104,717NCBI
Celera724,312,617 - 24,320,302 (+)NCBI
Cytogenetic Map7p15.3NCBI
HuRef724,208,802 - 24,216,490 (+)NCBIHuRef
CHM1_1724,325,406 - 24,333,092 (+)NCBICHM1_1
CRA_TCAGchr7v2724,375,683 - 24,383,371 (+)NCBI
Npy
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39649,799,690 - 49,806,487 (+)NCBIGRCm39mm39
GRCm39 Ensembl649,799,690 - 49,806,487 (+)Ensembl
GRCm38649,822,710 - 49,829,507 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl649,822,710 - 49,829,507 (+)EnsemblGRCm38mm10GRCm38
MGSCv37649,772,728 - 49,779,506 (+)NCBIGRCm37mm9NCBIm37
MGSCv36649,752,315 - 49,759,093 (+)NCBImm8
Celera650,334,213 - 50,340,981 (+)NCBICelera
Cytogenetic Map6B2.3NCBI
cM Map624.04NCBI
Npy
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541026,348,504 - 26,355,297 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541026,348,388 - 26,355,232 (+)NCBIChiLan1.0ChiLan1.0
NPY
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1724,566,963 - 24,574,657 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl724,568,041 - 24,574,657 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0724,963,056 - 24,970,803 (+)NCBIMhudiblu_PPA_v0panPan3
NPY
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11437,824,579 - 37,831,289 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1437,823,861 - 37,831,443 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1437,373,133 - 37,380,851 (+)NCBI
ROS_Cfam_1.01437,758,052 - 37,765,788 (+)NCBI
UMICH_Zoey_3.11437,872,113 - 37,879,841 (+)NCBI
UNSW_CanFamBas_1.01437,564,477 - 37,572,202 (+)NCBI
UU_Cfam_GSD_1.01437,908,665 - 37,916,390 (+)NCBI
Npy
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511882,077,623 - 82,085,085 (+)NCBI
SpeTri2.0NW_0049364781,289,437 - 1,296,819 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NPY
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1847,985,725 - 47,993,289 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11847,985,796 - 47,993,726 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21852,929,745 - 52,937,666 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NPY
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12134,068,533 - 34,076,205 (-)NCBI
ChlSab1.1 Ensembl2134,068,530 - 34,075,127 (-)Ensembl
Npy
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247396,277,704 - 6,285,454 (-)NCBI

Position Markers
D4Wox21  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,882,817 - 78,882,954 (+)MAPPER
Rnor_6.0479,575,534 - 79,575,667NCBIRnor6.0
Rnor_6.0479,559,380 - 79,559,514NCBIRnor6.0
Rnor_5.04144,249,326 - 144,249,459UniSTSRnor5.0
Rnor_5.04144,235,277 - 144,235,411UniSTSRnor5.0
RGSC_v3.4478,039,509 - 78,039,646RGDRGSC3.4
RGSC_v3.4478,039,510 - 78,039,646UniSTSRGSC3.4
RGSC_v3.1478,315,639 - 78,315,776RGD
Celera473,796,672 - 73,796,816UniSTS
RH 3.4 Map4504.2UniSTS
RH 3.4 Map4504.2RGD
RH 2.0 Map4547.5RGD
Cytogenetic Map4q24UniSTS
D4Hri1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,882,817 - 78,882,945 (+)MAPPER
Rnor_6.0479,575,534 - 79,575,658NCBIRnor6.0
Rnor_6.0479,559,380 - 79,559,505NCBIRnor6.0
Rnor_5.04144,249,326 - 144,249,450UniSTSRnor5.0
Rnor_5.04144,235,277 - 144,235,402UniSTSRnor5.0
RGSC_v3.4478,039,510 - 78,039,637UniSTSRGSC3.4
RGSC_v3.4478,039,509 - 78,039,637RGDRGSC3.4
Celera473,796,672 - 73,796,807UniSTS
Cytogenetic Map4q24UniSTS
D4Mgh4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,878,504 - 78,878,711 (+)MAPPER
Rnor_6.0479,570,971 - 79,571,177NCBIRnor6.0
Rnor_6.0479,555,067 - 79,555,273NCBIRnor6.0
Rnor_5.04144,230,964 - 144,231,170UniSTSRnor5.0
Rnor_5.04144,244,763 - 144,244,969UniSTSRnor5.0
RGSC_v3.4478,035,196 - 78,035,403RGDRGSC3.4
RGSC_v3.4478,035,197 - 78,035,403UniSTSRGSC3.4
RGSC_v3.1478,311,326 - 78,311,533RGD
Celera473,792,358 - 73,792,564UniSTS
RH 3.4 Map4504.3UniSTS
RH 3.4 Map4504.3RGD
RH 2.0 Map4551.7RGD
SHRSP x BN Map437.38RGD
FHH x ACI Map446.9099RGD
Cytogenetic Map4q24UniSTS
D4Wox22  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,885,989 - 78,886,137 (+)MAPPER
Rnor_6.0479,578,703 - 79,578,854NCBIRnor6.0
Rnor_6.0479,562,550 - 79,562,701NCBIRnor6.0
Rnor_5.04144,252,495 - 144,252,646UniSTSRnor5.0
Rnor_5.04144,238,447 - 144,238,598UniSTSRnor5.0
RGSC_v3.4478,042,681 - 78,042,833RGDRGSC3.4
RGSC_v3.4478,042,682 - 78,042,833UniSTSRGSC3.4
RGSC_v3.1478,318,811 - 78,318,963RGD
Celera473,799,852 - 73,800,013UniSTS
RH 3.4 Map4508.4UniSTS
RH 3.4 Map4508.4RGD
RH 2.0 Map4543.9RGD
Cytogenetic Map4q24UniSTS
D4Arb7  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,885,867 - 78,886,157 (+)MAPPER
Rnor_6.0479,578,581 - 79,578,874NCBIRnor6.0
Rnor_6.0479,562,428 - 79,562,721NCBIRnor6.0
Rnor_5.04144,238,325 - 144,238,618UniSTSRnor5.0
Rnor_5.04144,252,373 - 144,252,666UniSTSRnor5.0
RGSC_v3.4478,042,559 - 78,042,853RGDRGSC3.4
RGSC_v3.4478,042,560 - 78,042,853UniSTSRGSC3.4
RGSC_v3.1478,318,689 - 78,318,983RGD
Celera473,799,730 - 73,800,033UniSTS
FHH x ACI Map446.9099RGD
FHH x ACI Map446.9099UniSTS
Cytogenetic Map4q24UniSTS
D4Mit7  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,885,890 - 78,886,189 (+)MAPPER
Rnor_6.0479,562,451 - 79,562,753RGDRnor6.0
D4Mit24  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,882,815 - 78,882,945 (+)MAPPER
Rnor_6.0479,575,532 - 79,575,658NCBIRnor6.0
Rnor_6.0479,559,378 - 79,559,505NCBIRnor6.0
Rnor_5.04144,235,275 - 144,235,402UniSTSRnor5.0
Rnor_5.04144,249,324 - 144,249,450UniSTSRnor5.0
RGSC_v3.4478,039,507 - 78,039,637RGDRGSC3.4
RGSC_v3.4478,039,508 - 78,039,637UniSTSRGSC3.4
RGSC_v3.1478,315,637 - 78,315,767RGD
Celera473,796,670 - 73,796,807UniSTS
RH 3.4 Map4500.0RGD
RH 3.4 Map4500.0UniSTS
RH 2.0 Map4554.5RGD
Cytogenetic Map4q24UniSTS
D4Arb35  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,882,815 - 78,882,964 (+)MAPPER
Rnor_6.0479,575,532 - 79,575,677NCBIRnor6.0
Rnor_6.0479,559,378 - 79,559,524NCBIRnor6.0
Rnor_5.04144,235,275 - 144,235,421UniSTSRnor5.0
Rnor_5.04144,249,324 - 144,249,469UniSTSRnor5.0
RGSC_v3.4478,039,507 - 78,039,656RGDRGSC3.4
RGSC_v3.4478,039,508 - 78,039,656UniSTSRGSC3.4
RGSC_v3.1478,315,637 - 78,315,786RGD
Celera473,796,670 - 73,796,826UniSTS
FHH x ACI Map446.34RGD
FHH x ACI Map446.34UniSTS
Cytogenetic Map4q24UniSTS
D14Mit29  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,885,890 - 78,886,189 (+)MAPPER
Rnor_6.0479,578,604 - 79,578,906NCBIRnor6.0
Rnor_6.0479,562,451 - 79,562,753NCBIRnor6.0
Rnor_5.04144,238,348 - 144,238,650UniSTSRnor5.0
Rnor_5.04144,252,396 - 144,252,698UniSTSRnor5.0
RGSC_v3.4478,042,583 - 78,042,885UniSTSRGSC3.4
Celera473,799,753 - 73,800,065UniSTS
Cytogenetic Map4q24UniSTS
RH94804  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,886,166 - 78,886,421 (+)MAPPER
Rnor_6.0479,578,884 - 79,579,138NCBIRnor6.0
Rnor_6.0479,562,731 - 79,562,985NCBIRnor6.0
Rnor_5.04144,252,676 - 144,252,930UniSTSRnor5.0
Rnor_5.04144,238,628 - 144,238,882UniSTSRnor5.0
RGSC_v3.4478,042,863 - 78,043,117UniSTSRGSC3.4
Celera473,800,043 - 73,800,297UniSTS
RH 3.4 Map4508.6UniSTS
Cytogenetic Map4q24UniSTS
D14Mit29.1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,885,833 - 78,885,943 (+)MAPPER
Rnor_6.0479,578,547 - 79,578,656NCBIRnor6.0
Rnor_6.0479,562,394 - 79,562,503NCBIRnor6.0
Rnor_5.04144,238,291 - 144,238,400UniSTSRnor5.0
Rnor_5.04144,252,339 - 144,252,448UniSTSRnor5.0
RGSC_v3.4478,042,526 - 78,042,635UniSTSRGSC3.4
Celera473,799,696 - 73,799,805UniSTS
Cytogenetic Map4q24UniSTS
RH94574  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,888,361 - 78,888,460 (+)MAPPER
Rnor_6.0479,581,079 - 79,581,177NCBIRnor6.0
Rnor_6.0479,564,926 - 79,565,024NCBIRnor6.0
Rnor_5.04144,240,823 - 144,240,921UniSTSRnor5.0
Rnor_5.04144,254,871 - 144,254,969UniSTSRnor5.0
RGSC_v3.4478,045,058 - 78,045,156UniSTSRGSC3.4
Celera473,802,238 - 73,802,336UniSTS
Cytogenetic Map4q24UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4304323179575658Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)43043231145254791Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)4734240492484039Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)47850904182171018Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)423850384169318094Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)42665474981874227Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)429549895112807890Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43182556083531021Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)43182556083531021Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43182556083531021Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)43427793299067150Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)436615599145611886Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)437703272115372927Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)43920822284208222Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)43920824784208247Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44241577787415777Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)443414605155469929Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)443414792146942075Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)443414792146942075Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)446898276145611886Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)449906054145611886Rat
4889969Bss96Bone structure and strength QTL 964.9tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)45532485779575658Rat
4889972Bss97Bone structure and strength QTL 975.6tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)45532485779575658Rat
5685009Bmd86Bone mineral density QTL 863.7tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)45532485779575658Rat
5685012Bmd87Bone mineral density QTL 875.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)45532485779575658Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)455324953148360954Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)455375865125671711Rat
634311Sach7Saccharin preference QTL 7taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)45579156482134846Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45579156492484312Rat
61336Bp21Blood pressure QTL 214.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45579183479557856Rat
1578657Bss12Bone structure and strength QTL 128.9femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)456092756101092756Rat
1578658Bss13Bone structure and strength QTL 138femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)456092756101092756Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)45710107792990863Rat
631671Iddm11Insulin dependent diabetes mellitus QTL 113.60.0012blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)45730707579578854Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)458166424103166424Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)458640017154427984Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)458640017154427984Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)458640017154427984Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)46043912799066957Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)460439127113416139Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)461038901127777403Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46170810388565113Rat
8552807Vie4Viral induced encephalitis QTL 47.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)46170834183531021Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)461708341113100992Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)461708341113100992Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)461708341113100992Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in mean arterial blood pressure (CMO:0002035)461708341113100992Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in systolic blood pressure (CMO:0000747)461708341113100992Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in pulse pressure (CMO:0001882)461708341113100992Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)461708341113100992Rat
2300179Bmd50Bone mineral density QTL 505.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)461975371106975371Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)462947687125671711Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)463537179157286626Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)463812687108812687Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)463812687108812687Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)463812687108812687Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)463938412108938412Rat
2312569Pur19Proteinuria QTL 193.40.001total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)46598924397759057Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470773471132455556Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)471476518116476518Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)471476518116476518Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473786419132455556Rat
724522Bp146Blood pressure QTL 1462.20.0021arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)475258970120258970Rat
2302051Pia28Pristane induced arthritis QTL 285.30.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)475258970120258970Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)476567036121567036Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)477307388116916073Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)477307388116916073Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)479555067124555067Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)479557856116916073Rat
2317586Eae25Experimental allergic encephalomyelitis QTL 259.300000190734863nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)47955938084053053Rat
2317586Eae25Experimental allergic encephalomyelitis QTL 259.300000190734863nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)47955938084053053Rat
2317586Eae25Experimental allergic encephalomyelitis QTL 259.300000190734863nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)47955938084053053Rat
2317586Eae25Experimental allergic encephalomyelitis QTL 259.300000190734863nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)47955938084053053Rat
61364Iddm2Insulin dependent diabetes mellitus QTL 2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)47956245198542106Rat


Related Rat Strains
The following Strains have been annotated to Npy


Genetic Models
This gene Npy is modified in the following models/strains
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:127
Count of miRNA genes:106
Interacting mature miRNAs:110
Transcripts:ENSRNOT00000013145
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system exocrine system hemolymphoid system hepatobiliary system nervous system reproductive system
High
Medium
Low
Below cutoff 4 4 1 4 15 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000013145   ⟹   ENSRNOP00000013146
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl479,557,854 - 79,565,097 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000074351   ⟹   ENSRNOP00000066713
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl479,573,998 - 79,581,208 (+)Ensembl
RefSeq Acc Id: NM_012614   ⟹   NP_036746
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2478,881,294 - 78,888,495 (+)NCBI
Rnor_6.0479,557,856 - 79,565,059 (+)NCBI
Rnor_5.04144,233,753 - 144,240,956 (+)NCBI
RGSC_v3.4478,038,013 - 78,045,187 (+)RGD
Celera473,795,148 - 73,802,371 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_036746   ⟸   NM_012614
- Peptide Label: preproprotein
- UniProtKB: P07808 (UniProtKB/Swiss-Prot),   F2W8A6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000013146   ⟸   ENSRNOT00000013145
RefSeq Acc Id: ENSRNOP00000066713   ⟸   ENSRNOT00000074351

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693045
Promoter ID:EPDNEW_R3565
Type:single initiation site
Name:Npy_1
Description:neuropeptide Y
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0479,574,024 - 79,574,084EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3197 AgrOrtholog
  RGD:6487865 AgrOrtholog
BIND 133988
Ensembl Genes ENSRNOG00000009768 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00000046449 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000013146 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000066713 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000013145 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000074351 UniProtKB/Swiss-Prot
InterPro Pancreatic_hormone-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pancreatic_hormone-like_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:100912228 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  rno:24604 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 24604 ENTREZGENE
PANTHER PTHR10533 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Hormone_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB NPY RGD
PhenoGen Npy PhenoGen
PRINTS PANCHORMONE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PANCREATIC_HORMONE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PANCREATIC_HORMONE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PAH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC232176
UniProt F2W8A6 ENTREZGENE, UniProtKB/TrEMBL
  NPY_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary M0RAZ3 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Npy  neuropeptide Y  LOC100912228  pro-neuropeptide Y-like  Data Merged 737654 PROVISIONAL
2012-07-05 LOC100912228  pro-neuropeptide Y-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Npy  Neuropeptide Y      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression present in the hypothalamus of obese rats, especially in the paraventricular nucleus 70437
gene_expression abundant in central and peripheral nervous system 628512
gene_expression expressed throughout nervous system; increased expression in brain areas undergoing seizures 628420
gene_function inhibitory neurotransmitter that controls blood pressure 1357410
gene_function hypothalamic-derived neuropeptide 628420
gene_function hypothalamic-derived neuropeptide 628512
gene_other exogenous Npy has long-lasting effects on postsynaptic current amplitude in neocortex 628420
gene_physical_interaction binds to G protein coupled pancreatic polypeptide (Pp) receptors Y1,Y2 and Y5 628420
gene_process mediates the control of stress and fear related behavior 1357416
gene_process regulates appetite 70437
gene_process activates G-protein coupled receptors 70437
gene_process may function as an endogenous antiepileptic agent 628512
gene_process involved in energy homeostasis 628420
gene_process may be involved in modulation of Ca2+ dependent GABA release onto pyramidal neurons 628420
gene_process involved in modulation of feeding behaviour, anxiety, memory consolidation, and regulation of blood pressure; may decrease excitatory postsynaptic current and increase monosynaptic inhibitory postsynaptic current 628420
gene_process mediates effects of leptin on energy homeostasis; may influence hypothalamic-pituitary-thyroid axis (HPT axis) 628420
gene_regulation decrease in hypothalamic NPY innervation observed in anorectic TB rats 727497
gene_transcript polymorphism at position +4666 defined by microsatellite marker D4Mit7, contributes to reduced levels of mRNA expression in brain regions of alcohol preferring (iP) rats 1357412