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Gene: Rasgrp3 (RAS guanyl releasing protein 3) Rattus norvegicus
Symbol: Rasgrp3
Name: RAS guanyl releasing protein 3
Description: Predicted to have GTPase activator activity; Ras guanyl-nucleotide exchange factor activity; and kinase binding activity. Predicted to be involved in Ras protein signal transduction and regulation of GTPase activity. Predicted to localize to the guanyl-nucleotide exchange factor complex and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human RASGRP3 (RAS guanyl releasing protein 3); PARTICIPATES IN B cell receptor signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.
Type: protein-coding
Also known as: LOC313874; RAS guanyl releasing protein 3 (calcium and DAG-regulated); ras guanyl-releasing protein 3; RAS, guanyl releasing protein 3
Homo sapiens (human) : RASGRP3 (RAS guanyl releasing protein 3)  HGNC  Alliance
Mus musculus (house mouse) : Rasgrp3 (RAS, guanyl releasing protein 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rasgrp3 (RAS guanyl releasing protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : RASGRP3 (RAS guanyl releasing protein 3)
Canis lupus familiaris (dog) : RASGRP3 (RAS guanyl releasing protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rasgrp3 (RAS guanyl releasing protein 3)
Sus scrofa (pig) : RASGRP3 (RAS guanyl releasing protein 3)
more info ...
Allele / Splice: Rasgrp3em1Mcwi   Rasgrp3em3Mcwi  
Genetic Models: SS-Rasgrp3em1Mcwi SS-Rasgrp3em3Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0621,072,634 - 21,171,619 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0630,966,364 - 31,065,175 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4619,808,453 - 19,871,923 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1619,815,248 - 19,848,714 (-)NCBI
Celera619,464,356 - 19,527,205 (-)NCBICelera
Cytogenetic Map6q12-q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Rasgrp3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1304612
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.