Alc17 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Alc17 (Alcohol consumption QTL 17) Rattus norvegicus

Symbol: Alc17
Name: Alcohol consumption QTL 17
RGD ID: 738023
Previously known as: Consumption of Ethanol 5%; Coet5a
Trait: consumption behavior trait   (VT:0002069)    
Measurement Type: ethanol drink intake rate to body weight ratio   (CMO:0001616)    
LOD Score: 3.1
P Value: 0.003
Variance: 38.0
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.261 - 27,574,569RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.061 - 35,623,029RGD_MAPPER_PIPELINERnor6.0
Rnor_5.06580,292 - 45,580,292RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.461 - 35,786,687RGD_MAPPER_PIPELINERGSC3.4
RGSC_v3.160 - 35,786,687RGD
Cross Type: intercross
Strains Crossed: WKY HEP 




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alc17Ratalcohol use disorder  IDA 731213 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alc17Ratalcohol preference  QTM 731213 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alc17Ratethanol drink intake rate to body weight ratio  IDA 731213 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alc17Ratcontrolled ethanol content drinking water  IDA 731213 RGD 
Alc17Ratwater  IDA 731213 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alc17Ratscale  IDA 731213 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alc17RatHEP  IEA 731213 RGD 
Alc17RatWKY  IEA 731213 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alc17Ratconsumption behavior trait  IDA 731213 RGD 


#
Reference Title
Reference Citation
1. Genetics of behaviour: phenotypic and molecular study of rats derived from high- and low-alcohol consuming lines. Terenina-Rigaldie E, etal., Pharmacogenetics 2003 Sep;13(9):543-54.

Related QTL Description Reference
Sach4 interacts with RGD:731213
Sach5 interacts with RGD:731213
Alc14 interacts with RGD:731213
Alc15 interacts with RGD:731213
Alc16 interacts with RGD:731213



1 to 20 of 339 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1585856Ralbp1l2ralA binding protein 1 like 2638788192192Rat
41317278Txnl4al2thioredoxin-like 4A like 26111150111805Rat
7685759Naa11-ps2N(alpha)-acetyltransferase 11, NatA catalytic subunit, pseudogene 26111437112376Rat
11409802LOC108350029uncharacterized LOC1083500296118567177281Rat
1310083Cwf19l2CWF19 like cell cycle control factor 26290148356636Rat
41248162Tmem126a-ps4transmembrane protein 126A, pseudogene 46310136310857Rat
1304687Alkbh8alkB homolog 8, tRNA methyltransferase6378779449382Rat
7740587Pank3-ps2pantothenate kinase 3, pseudogene 26402201406363Rat
1304582Mtm1myotubularin 16488923506882Rat
7723359LOC102553826uncharacterized LOC1025538266507112528358Rat
1596478Rrs1-ps15ribosome biogenesis regulator 1 homolog, pseudogene 156540847548560Rat
2319303Egln1-ps6egl-9 family hypoxia-inducible factor 1, pseudogene 66556312561717Rat
1597710Car13l1carbonic anhydrase 13 like 16615673623476Rat
1564275Znhit1-ps1zinc finger, HIT-type containing 1, pseudogene 16887012887449Rat
7242712Crnkl1-ps1crooked neck pre-mRNA splicing factor 1, pseudogene 1611406151142929Rat
41289894LOC120093494small nucleolar RNA U3612524181252490Rat
1560460Ppp1cb-ps7protein phosphatase 1 catalytic subunit beta, pseudogene 7613918881394865Rat
1309234Uap1l2UDP-N-acetylglucosamine pyrophosphorylase 1 like 2617143201741396Rat
6502562Wac-ps1WW domain containing adaptor with coiled-coil, pseudogene 1620002782003353Rat
2321089LOC100360971hypothetical LOC100360971620200262110273Rat

1 to 20 of 339 rows
1 to 20 of 422 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
33561D6Mit5171653450075345178Ratregion
36344D12Mit10121615766581576779Ratregion
37298D6Rat10521961872366018723879Ratregion
37410D6Rat10717361952217919522352Ratregion
37496D6Rat108138622993572299495Ratregion
37562D6Rat7715262266434522664497Ratregion
35411D6Rat5614461440416214404306Ratregion
35507D6Rat4317761995589919956076Ratregion
35541D6Rat47146638929043893050Ratregion
37000D6Rat18015561749359817493753Ratregion
37142D6Rat8025261653614016536392Ratregion
36737D6Rat4417761633650916336688Ratregion
34843D6Rat4014961653624316536392Ratregion
35134D6Rat4125962086642220866681Ratregion
35579D6Rat5415562295900922959164Ratregion
35647D6Rat5515561511882815118983Ratregion
35653D6Rat4213961998791119988050Ratregion
35683D6Rat3913862033877720338915Ratregion
35963D6Rat46144650744975074641Ratregion
39622D6Rat151155637570193757174Ratregion
1 to 20 of 422 rows

Peak: (D6Rat46)
Rat AssemblyChrPosition (strand)Source
mRatBN7.265,074,497 - 5,074,641 (-)MAPPER
Rnor_6.0613,122,958 - 13,123,101NCBI
Rnor_5.0623,080,221 - 23,080,364UniSTS
RGSC_v3.4613,286,615 - 13,286,759RGD
RGSC_v3.4613,286,616 - 13,286,759UniSTS
RGSC_v3.1613,286,615 - 13,286,759RGD
Celera64,866,677 - 4,866,820UniSTS
SHRSP x BN Map61.1499UniSTS
SHRSP x BN Map61.1499RGD


1 to 10 of 39 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
1549905Stresp10Stress response QTL 106.830.0066stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)6127574569Rat
8693699Alc37Alcohol consumption QTL 372.60.224drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)6796416721301982Rat
8693645Alc31Alcohol consumption QTL 313.70.038drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)61753252124011952Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)6134235784Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat

1 to 10 of 39 rows


Database
Acc Id
Source(s)
NCBI Gene Alc17

Note Type Note Reference
qtl_cross_pair WKYxHEP  
qtl_cross_type intercross  
qtl_general no apparent influence of sex or sex-genotype interaction 731213
qtl_map same locus also maps a suggestive QTL for consumption of 7.5 mM saccharine (Sach5, LOD = 3.9) 731213