Msh2 (mutS homolog 2) - Rat Genome Database

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Gene: Msh2 (mutS homolog 2) Rattus norvegicus
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Symbol: Msh2
Name: mutS homolog 2
RGD ID: 620786
Description: Predicted to enable several functions, including ATP hydrolysis activity; DNA binding activity; and protein C-terminus binding activity. Predicted to contribute to several functions, including DNA binding activity; MutLalpha complex binding activity; and adenyl ribonucleotide binding activity. Involved in several processes, including response to amino acid; response to drug; and spermatogenesis. Located in nucleus. Biomarker of colitis and visual epilepsy. Human ortholog(s) of this gene implicated in several diseases, including Lynch syndrome (multiple); gastrointestinal system cancer (multiple); lung cancer (multiple); mismatch repair cancer syndrome; and transitional cell carcinoma. Orthologous to human MSH2 (mutS homolog 2); PARTICIPATES IN altered mismatch repair pathway; colorectal cancer pathway; mismatch repair pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DNA mismatch repair protein Msh2; mismatch repair protein; mutS homolog 2 (E. coli); mutS protein homolog 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.266,813,793 - 6,872,960 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl611,215,963 - 11,274,932 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0611,215,951 - 11,274,916 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0621,198,374 - 21,256,838 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4611,199,906 - 11,258,350 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1611,199,905 - 11,258,350 (+)NCBI
Celera66,571,260 - 6,630,220 (-)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model