Slc3a1 (solute carrier family 3 member 1) - Rat Genome Database

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Gene: Slc3a1 (solute carrier family 3 member 1) Rattus norvegicus
Analyze
Symbol: Slc3a1
Name: solute carrier family 3 member 1
RGD ID: 3709
Description: Predicted to enable protein heterodimerization activity. Involved in amino acid transport. Located in plasma membrane and vacuolar membrane. Human ortholog(s) of this gene implicated in cystinuria. Orthologous to human SLC3A1 (solute carrier family 3 member 1); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: b(0,+)-type amino acid transport protein; D2; NAA-TR; NBAT; neutral and basic amino acid transport protein rBAT; solute carrier family 3 (amino acid transporter heavy chain), member 1; solute carrier family 3, member 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.269,608,169 - 9,641,881 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl69,608,178 - 9,641,907 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx69,897,026 - 9,930,636 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0610,206,403 - 10,240,011 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.069,727,975 - 9,761,655 (-)NCBIRnor_WKY
Rnor_6.068,284,937 - 8,318,649 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl68,284,878 - 8,318,674 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.068,217,549 - 8,251,133 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.468,385,186 - 8,419,465 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.168,385,185 - 8,419,461 (+)NCBI
Celera69,332,403 - 9,366,072 (-)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Cystinuria caused by mutations in rBAT, a gene involved in the transport of cystine. Calonge MJ, etal., Nat Genet. 1994 Apr;6(4):420-5.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Membrane topology of the rat kidney neutral and basic amino acid transporter. Mosckovitz R, etal., FASEB J. 1994 Oct;8(13):1069-74.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. Regional and subcellular distribution of a neutral and basic amino acid transporter in forebrain neurons containing nitric oxide synthase. Pickel VM, etal., J Comp Neurol. 1999 Feb 22;404(4):459-72.
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
13. Expression cloning of a Na(+)-independent neutral amino acid transporter from rat kidney. Tate SS, etal., Proc Natl Acad Sci U S A 1992 Jan 1;89(1):1-5.
14. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
15. Oligomeric structure of a renal cystine transporter: implications in cystinuria. Wang Y and Tate SS, FEBS Lett. 1995 Jul 17;368(2):389-92.
16. Cloning of a rat kidney cDNA that stimulates dibasic and neutral amino acid transport and has sequence similarity to glucosidases. Wells RG and Hediger MA, Proc Natl Acad Sci U S A 1992 Jun 15;89(12):5596-600.
Additional References at PubMed
PMID:8052618   PMID:10506124   PMID:12167606   PMID:12865426   PMID:15489334   PMID:19056867   PMID:23376485  


Genomics

Comparative Map Data
Slc3a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.269,608,169 - 9,641,881 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl69,608,178 - 9,641,907 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx69,897,026 - 9,930,636 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0610,206,403 - 10,240,011 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.069,727,975 - 9,761,655 (-)NCBIRnor_WKY
Rnor_6.068,284,937 - 8,318,649 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl68,284,878 - 8,318,674 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.068,217,549 - 8,251,133 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.468,385,186 - 8,419,465 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.168,385,185 - 8,419,461 (+)NCBI
Celera69,332,403 - 9,366,072 (-)NCBICelera
Cytogenetic Map6q12NCBI
SLC3A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38244,275,480 - 44,322,437 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl244,275,458 - 44,321,494 (+)EnsemblGRCh38hg38GRCh38
GRCh37244,502,619 - 44,548,633 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36244,356,103 - 44,401,448 (+)NCBINCBI36Build 36hg18NCBI36
Build 34244,414,249 - 44,459,588NCBI
Celera244,341,552 - 44,386,916 (+)NCBICelera
Cytogenetic Map2p21NCBI
HuRef244,239,242 - 44,284,624 (+)NCBIHuRef
CHM1_1244,430,299 - 44,475,664 (+)NCBICHM1_1
T2T-CHM13v2.0244,280,847 - 44,326,811 (+)NCBIT2T-CHM13v2.0
Slc3a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391785,335,775 - 85,371,669 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1785,335,804 - 85,371,664 (+)EnsemblGRCm39 Ensembl
GRCm381785,028,347 - 85,064,241 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1785,028,376 - 85,064,236 (+)EnsemblGRCm38mm10GRCm38
MGSCv371785,427,687 - 85,463,581 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361784,936,718 - 84,983,241 (+)NCBIMGSCv36mm8
Celera1789,390,574 - 89,425,929 (+)NCBICelera
Cytogenetic Map17E4NCBI
cM Map1755.17NCBI
Slc3a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544111,381,441 - 11,418,025 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544111,381,390 - 11,418,193 (+)NCBIChiLan1.0ChiLan1.0
SLC3A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A45,307,885 - 45,356,055 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A45,307,885 - 45,355,386 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A44,371,328 - 44,419,611 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
SLC3A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11046,690,555 - 46,737,417 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1046,685,137 - 46,737,147 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1046,562,101 - 46,597,364 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01047,580,243 - 47,618,780 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1047,580,243 - 47,615,494 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11047,287,361 - 47,322,625 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01047,578,444 - 47,613,677 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01047,760,850 - 47,796,315 (+)NCBIUU_Cfam_GSD_1.0
Slc3a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629236,243,175 - 36,276,008 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365087,672,223 - 7,703,961 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365087,672,274 - 7,703,962 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC3A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl396,157,380 - 96,215,454 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1396,157,387 - 96,201,057 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23102,312,692 - 102,371,561 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC3A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11462,924,906 - 62,971,268 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1462,925,443 - 62,971,252 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604548,910,733 - 48,957,571 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc3a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473825,768,573 - 25,802,716 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473825,762,064 - 25,802,407 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc3a1
140 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:38
Count of miRNA genes:35
Interacting mature miRNAs:37
Transcripts:ENSRNOT00000009581
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738023Alc17Alcohol consumption QTL 173.10.003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)6127574569Rat
1354616Despr12Despair related QTL 120.0012locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)6127574569Rat
1549905Stresp10Stress response QTL 106.830.0066stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)6127574569Rat
2300176Bmd51Bone mineral density QTL 5111.70.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)6127574569Rat
2300190Bmd52Bone mineral density QTL 5211.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)6127574569Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)6134235784Rat
1578758Tcas9Tongue tumor susceptibility QTL 93.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)6137618905Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6139036266Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6141223769Rat
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6141223769Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6141223769Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6142487980Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6142487980Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6142487980Rat
7411584Foco4Food consumption QTL 44.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6142838846Rat
738024Sach5Saccharine consumption QTL 53.90.00039consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)6143394190Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
2293706Bmd20Bone mineral density QTL 204.30.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)6507449719988050Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449734434305Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat

Markers in Region
RH132752  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.269,608,328 - 9,608,534 (-)MAPPERmRatBN7.2
Rnor_6.068,318,284 - 8,318,489NCBIRnor6.0
Rnor_5.068,250,768 - 8,250,973UniSTSRnor5.0
RGSC_v3.468,419,100 - 8,419,305UniSTSRGSC3.4
Celera69,332,563 - 9,332,768UniSTS
Cytogenetic Map6q12UniSTS
AW535278  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.269,610,813 - 9,610,967 (-)MAPPERmRatBN7.2
Rnor_6.068,315,851 - 8,316,004NCBIRnor6.0
Rnor_5.068,248,335 - 8,248,488UniSTSRnor5.0
RGSC_v3.468,416,667 - 8,416,820UniSTSRGSC3.4
Celera69,335,053 - 9,335,206UniSTS
Cytogenetic Map6q12UniSTS
RH139082  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.269,609,676 - 9,609,859 (-)MAPPERmRatBN7.2
Rnor_6.068,316,959 - 8,317,141NCBIRnor6.0
Rnor_5.068,249,443 - 8,249,625UniSTSRnor5.0
RGSC_v3.468,417,775 - 8,417,957UniSTSRGSC3.4
Celera69,333,911 - 9,334,093UniSTS
Cytogenetic Map6q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 13
Medium 1 3 1 4 11 18 2 3 1
Low 2 8 27 11 19 11 7 7 2 4 26 8 7
Below cutoff 20 22 22 22 57 13

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000009581   ⟹   ENSRNOP00000009581
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl69,608,178 - 9,641,907 (-)Ensembl
Rnor_6.0 Ensembl68,284,878 - 8,318,674 (+)Ensembl
RefSeq Acc Id: NM_017216   ⟹   NP_058912
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.269,608,169 - 9,641,881 (-)NCBI
Rnor_6.068,284,937 - 8,318,649 (+)NCBI
Rnor_5.068,217,549 - 8,251,133 (+)NCBI
RGSC_v3.468,385,186 - 8,419,465 (+)RGD
Celera69,332,403 - 9,366,072 (-)RGD
Sequence:
Reference Sequences
RefSeq Acc Id: NP_058912   ⟸   NM_017216
- UniProtKB: Q62672 (UniProtKB/Swiss-Prot),   Q64319 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000009581   ⟸   ENSRNOT00000009581

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q64319-F1-model_v2 AlphaFold Q64319 1-683 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694379
Promoter ID:EPDNEW_R4904
Type:initiation region
Name:Slc3a1_1
Description:solute carrier family 3 member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.068,284,903 - 8,284,963EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3709 AgrOrtholog
BioCyc Gene G2FUF-38653 BioCyc
Ensembl Genes ENSRNOG00000007006 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000009581 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000009581 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.1180 UniProtKB/Swiss-Prot
  3.90.400.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7110514 IMAGE-MGC_LOAD
InterPro Glyco_hydro_13_cat_dom UniProtKB/Swiss-Prot
  Glyco_hydro_b UniProtKB/Swiss-Prot
  Glycoside_hydrolase_SF UniProtKB/Swiss-Prot
  O16G_dom_2 UniProtKB/Swiss-Prot
KEGG Report rno:29484 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93505 IMAGE-MGC_LOAD
NCBI Gene 29484 ENTREZGENE
Pfam Alpha-amylase UniProtKB/Swiss-Prot
PhenoGen Slc3a1 PhenoGen
SMART Aamy UniProtKB/Swiss-Prot
Superfamily-SCOP SSF51445 UniProtKB/Swiss-Prot
TIGR TC207343
UniProt Q62672 ENTREZGENE
  Q64319 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q62672 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-24 Slc3a1  solute carrier family 3 member 1  Slc3a1  solute carrier family 3 (amino acid transporter heavy chain), member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-03-16 Slc3a1  solute carrier family 3 (amino acid transporter heavy chain), member 1  Slc3a1  solute carrier family 3, member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Slc3a1  solute carrier family 3, member 1    solute carrier family 3, member 1   Name updated 629478 APPROVED
2002-06-10 Slc3a1  solute carrier family 3, member 1       Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains appears to have a single transmembrane domain 70013
gene_expression mRNA expressed specifically in kidney and intestine 70013
gene_protein putative protein is of 78 kDa 70013