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Gene: Slc3a1 (solute carrier family 3 member 1) Rattus norvegicus
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Symbol: Slc3a1
Name: solute carrier family 3 member 1
Description: Exhibits protein heterodimerization activity. Involved in amino acid transport. Localizes to the integral component of plasma membrane and vacuolar membrane. Human ortholog(s) of this gene implicated in cystinuria. Orthologous to human SLC3A1 (solute carrier family 3 member 1); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2,2-tetramine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: b(0,+)-type amino acid transport protein; D2; NAA-TR; NBAT; neutral and basic amino acid transport protein rBAT; solute carrier family 3 (amino acid transporter heavy chain), member 1; solute carrier family 3, member 1
Orthologs:
Homo sapiens (human) : SLC3A1 (solute carrier family 3 member 1)  HGNC  Alliance
Mus musculus (house mouse) : Slc3a1 (solute carrier family 3, member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc3a1 (solute carrier family 3 member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC3A1 (solute carrier family 3 member 1)
Canis lupus familiaris (dog) : SLC3A1 (solute carrier family 3 member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc3a1 (solute carrier family 3 member 1)
Sus scrofa (pig) : SLC3A1 (solute carrier family 3 member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.068,284,937 - 8,318,649 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.068,217,549 - 8,251,133 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.468,385,186 - 8,419,465 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.168,385,185 - 8,419,461 (+)NCBI
Celera69,332,403 - 9,366,072 (-)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Slc3a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3709
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.