Eml4 (EMAP like 4) - Rat Genome Database

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Gene: Eml4 (EMAP like 4) Rattus norvegicus
Analyze
Symbol: Eml4
Name: EMAP like 4
RGD ID: 1304690
Description: Predicted to enable alpha-tubulin binding activity; beta-tubulin binding activity; and microtubule binding activity. Predicted to be involved in attachment of spindle microtubules to kinetochore; microtubule cytoskeleton organization; and mitotic metaphase chromosome alignment. Predicted to act upstream of or within negative regulation of microtubule depolymerization. Predicted to be located in cytosol; microtubule cytoskeleton; and midbody. Predicted to colocalize with mitotic spindle. Orthologous to human EML4 (EMAP like 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: echinoderm microtubule associated protein like 4; echinoderm microtubule-associated protein-like 4; LOC313861
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8616,972,054 - 17,087,365 (-)NCBIGRCr8
mRatBN7.2611,219,545 - 11,334,824 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl611,219,566 - 11,334,879 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx611,513,029 - 11,569,371 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0611,822,359 - 11,878,704 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0611,335,631 - 11,391,915 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.066,618,370 - 6,674,550 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl66,619,076 - 6,674,554 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.066,573,560 - 6,629,053 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.466,754,664 - 6,813,231 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.166,694,898 - 6,811,133 (+)NCBI
Celera610,924,478 - 10,979,707 (-)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium dichloride  (EXP)
caffeine  (ISO)
CGP 52608  (ISO)
chloroprene  (EXP)
cobalt dichloride  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
crizotinib  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
diuron  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
folic acid  (ISO)
FR900359  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
irinotecan  (EXP)
ivermectin  (ISO)
lead diacetate  (ISO)
leflunomide  (EXP)
Mecamylamine  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
N,N-diethyl-m-toluamide  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
nicotine  (ISO)
nimesulide  (EXP)
Nivalenol  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
tert-butyl hydroperoxide  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
tubocurarine  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc protoporphyrin  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17196341   PMID:19946888   PMID:24625528   PMID:35659652  


Genomics

Comparative Map Data
Eml4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8616,972,054 - 17,087,365 (-)NCBIGRCr8
mRatBN7.2611,219,545 - 11,334,824 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl611,219,566 - 11,334,879 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx611,513,029 - 11,569,371 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0611,822,359 - 11,878,704 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0611,335,631 - 11,391,915 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.066,618,370 - 6,674,550 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl66,619,076 - 6,674,554 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.066,573,560 - 6,629,053 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.466,754,664 - 6,813,231 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.166,694,898 - 6,811,133 (+)NCBI
Celera610,924,478 - 10,979,707 (-)NCBICelera
Cytogenetic Map6q12NCBI
EML4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38242,169,353 - 42,332,548 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl242,169,353 - 42,332,548 (+)EnsemblGRCh38hg38GRCh38
GRCh37242,396,493 - 42,559,688 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36242,250,020 - 42,413,192 (+)NCBINCBI36Build 36hg18NCBI36
Build 34242,308,166 - 42,471,337NCBI
Celera242,236,800 - 42,399,970 (+)NCBICelera
Cytogenetic Map2p21NCBI
HuRef242,130,861 - 42,294,053 (+)NCBIHuRef
CHM1_1242,326,032 - 42,489,120 (+)NCBICHM1_1
T2T-CHM13v2.0242,174,851 - 42,337,951 (+)NCBIT2T-CHM13v2.0
Eml4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391783,658,341 - 83,787,790 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1783,658,360 - 83,787,790 (+)EnsemblGRCm39 Ensembl
GRCm381783,350,930 - 83,480,361 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1783,350,931 - 83,480,361 (+)EnsemblGRCm38mm10GRCm38
MGSCv371783,750,271 - 83,879,701 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361783,259,308 - 83,388,687 (+)NCBIMGSCv36mm8
Celera1787,692,800 - 87,822,185 (+)NCBICelera
Cytogenetic Map17E4NCBI
cM Map1752.69NCBI
Eml4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554419,640,899 - 9,713,596 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554419,633,906 - 9,715,866 (+)NCBIChiLan1.0ChiLan1.0
EML4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21284,077,821 - 84,240,653 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A84,081,794 - 84,244,603 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A42,267,435 - 42,430,231 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A43,119,984 - 43,281,825 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A43,119,984 - 43,281,825 (+)Ensemblpanpan1.1panPan2
EML4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11733,774,478 - 33,935,478 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1733,774,140 - 33,934,147 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1733,544,396 - 33,704,779 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01734,541,313 - 34,702,667 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1734,541,324 - 34,723,308 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11733,666,618 - 33,827,461 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01733,729,208 - 33,890,080 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01733,946,661 - 34,107,545 (+)NCBIUU_Cfam_GSD_1.0
Eml4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629237,875,039 - 38,018,878 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365089,303,639 - 9,447,548 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365089,303,639 - 9,447,478 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EML4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl398,005,812 - 98,155,846 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1398,005,809 - 98,155,876 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23104,141,153 - 104,291,245 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EML4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11464,927,288 - 65,090,904 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1464,929,617 - 65,090,861 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604546,810,153 - 46,977,133 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eml4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473823,887,782 - 24,048,204 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473823,887,822 - 24,045,864 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Eml4
572 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:241
Count of miRNA genes:175
Interacting mature miRNAs:197
Transcripts:ENSRNOT00000042307
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
1549905Stresp10Stress response QTL 106.830.0066stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)6127574569Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)6134235784Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
1578758Tcas9Tongue tumor susceptibility QTL 93.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)6137618905Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6141223769Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6139036266Rat
738024Sach5Saccharine consumption QTL 53.90.00039consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)6143394190Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6141223769Rat
2293706Bmd20Bone mineral density QTL 204.30.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)6507449719988050Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6141223769Rat
2292616Ept15Estrogen-induced pituitary tumorigenesis QTL 154.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6984331220338915Rat
738023Alc17Alcohol consumption QTL 173.10.003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)6127574569Rat
1354616Despr12Despair related QTL 120.0012locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)6127574569Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6142487980Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6142487980Rat
7411584Foco4Food consumption QTL 44.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6142838846Rat
2300176Bmd51Bone mineral density QTL 5111.70.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)6127574569Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449734434305Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6142487980Rat
1358190Ept1Estrogen-induced pituitary tumorigenesis QTL 14.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6984331220338915Rat
2300190Bmd52Bone mineral density QTL 5211.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)6127574569Rat

Markers in Region
AI644019  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2611,219,742 - 11,219,843 (-)MAPPERmRatBN7.2
Rnor_6.066,674,252 - 6,674,352NCBIRnor6.0
Rnor_5.066,628,755 - 6,628,855UniSTSRnor5.0
RGSC_v3.466,812,954 - 6,813,054UniSTSRGSC3.4
Celera610,924,655 - 10,924,755UniSTS
Cytogenetic Map6q12UniSTS
RH138441  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2611,220,511 - 11,220,740 (-)MAPPERmRatBN7.2
Rnor_6.066,673,355 - 6,673,583NCBIRnor6.0
Rnor_5.066,627,858 - 6,628,086UniSTSRnor5.0
RGSC_v3.466,812,057 - 6,812,285UniSTSRGSC3.4
Celera610,925,424 - 10,925,652UniSTS
RH 3.4 Map1529.4UniSTS
Cytogenetic Map6q12UniSTS
RH140067  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2611,269,489 - 11,269,639 (-)MAPPERmRatBN7.2
Rnor_6.066,624,460 - 6,624,609NCBIRnor6.0
Rnor_5.066,578,963 - 6,579,112UniSTSRnor5.0
RGSC_v3.466,760,048 - 6,760,197UniSTSRGSC3.4
Celera610,974,174 - 10,974,323UniSTS
Cytogenetic Map6q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 29 57 41 19 41 1 1 74 33 38 11 1
Low 14 7 9 2 3 7
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC112092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000042307   ⟹   ENSRNOP00000050319
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl611,219,566 - 11,334,879 (-)Ensembl
Rnor_6.0 Ensembl66,619,076 - 6,674,529 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000080013   ⟹   ENSRNOP00000072435
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl611,219,566 - 11,334,879 (-)Ensembl
Rnor_6.0 Ensembl66,619,081 - 6,674,554 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111306   ⟹   ENSRNOP00000094437
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl611,219,566 - 11,273,466 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000116346   ⟹   ENSRNOP00000087686
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl611,219,566 - 11,334,879 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118377   ⟹   ENSRNOP00000076696
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl611,219,566 - 11,334,879 (-)Ensembl
RefSeq Acc Id: NM_001108008   ⟹   NP_001101478
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8616,972,075 - 17,027,530 (-)NCBI
mRatBN7.2611,219,566 - 11,275,023 (-)NCBI
Rnor_6.066,619,076 - 6,674,529 (+)NCBI
Rnor_5.066,573,560 - 6,629,053 (+)NCBI
RGSC_v3.466,754,664 - 6,813,231 (+)RGD
Celera610,924,478 - 10,979,707 (-)RGD
Sequence:
RefSeq Acc Id: XM_039112148   ⟹   XP_038968076
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8616,972,054 - 17,087,365 (-)NCBI
mRatBN7.2611,219,545 - 11,334,824 (-)NCBI
RefSeq Acc Id: XM_039112149   ⟹   XP_038968077
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8616,972,054 - 17,087,365 (-)NCBI
mRatBN7.2611,219,545 - 11,334,824 (-)NCBI
RefSeq Acc Id: XM_039112150   ⟹   XP_038968078
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8616,972,054 - 17,087,365 (-)NCBI
mRatBN7.2611,219,545 - 11,334,824 (-)NCBI
RefSeq Acc Id: XM_039112151   ⟹   XP_038968079
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8616,972,054 - 17,087,365 (-)NCBI
mRatBN7.2611,219,545 - 11,334,824 (-)NCBI
RefSeq Acc Id: XM_039112152   ⟹   XP_038968080
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8616,972,054 - 17,087,365 (-)NCBI
mRatBN7.2611,219,545 - 11,334,823 (-)NCBI
RefSeq Acc Id: XM_039112153   ⟹   XP_038968081
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8616,972,054 - 17,087,365 (-)NCBI
mRatBN7.2611,219,545 - 11,334,823 (-)NCBI
RefSeq Acc Id: XM_039112154   ⟹   XP_038968082
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8616,972,054 - 17,009,159 (-)NCBI
mRatBN7.2611,219,545 - 11,256,654 (-)NCBI
RefSeq Acc Id: NP_001101478   ⟸   NM_001108008
- UniProtKB: A6H9N1 (UniProtKB/TrEMBL),   A6H9N0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072435   ⟸   ENSRNOT00000080013
Ensembl Acc Id: ENSRNOP00000050319   ⟸   ENSRNOT00000042307
RefSeq Acc Id: XP_038968079   ⟸   XM_039112151
- Peptide Label: isoform X4
- UniProtKB: A6H9N0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968078   ⟸   XM_039112150
- Peptide Label: isoform X3
- UniProtKB: F1LT71 (UniProtKB/TrEMBL),   A6H9N0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968077   ⟸   XM_039112149
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A8G5 (UniProtKB/TrEMBL),   A0A8I6ALM1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968076   ⟸   XM_039112148
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2Z0 (UniProtKB/TrEMBL),   A0A8I6ALM1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968081   ⟸   XM_039112153
- Peptide Label: isoform X6
- UniProtKB: A6H9N0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968080   ⟸   XM_039112152
- Peptide Label: isoform X5
- UniProtKB: A0A8I5Y0M9 (UniProtKB/TrEMBL),   A6H9N0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968082   ⟸   XM_039112154
- Peptide Label: isoform X7
Ensembl Acc Id: ENSRNOP00000076696   ⟸   ENSRNOT00000118377
Ensembl Acc Id: ENSRNOP00000087686   ⟸   ENSRNOT00000116346
Ensembl Acc Id: ENSRNOP00000094437   ⟸   ENSRNOT00000111306
Protein Domains
HELP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K2Z0-F1-model_v2 AlphaFold A0A0G2K2Z0 1-914 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304690 AgrOrtholog
BioCyc Gene G2FUF-38607 BioCyc
Ensembl Genes ENSRNOG00000030294 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000042307.5 UniProtKB/TrEMBL
  ENSRNOT00000080013.2 UniProtKB/TrEMBL
  ENSRNOT00000111306.1 UniProtKB/TrEMBL
  ENSRNOT00000116346.1 UniProtKB/TrEMBL
  ENSRNOT00000118377.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro HELP UniProtKB/TrEMBL
  Quinonprotein_ADH-like UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report rno:313861 UniProtKB/TrEMBL
NCBI Gene 313861 ENTREZGENE
PANTHER ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 4 UniProtKB/TrEMBL
  WD-40 REPEAT PROTEIN UniProtKB/TrEMBL
Pfam HELP UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PhenoGen Eml4 PhenoGen
PROSITE WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
RatGTEx ENSRNOG00000030294 RatGTEx
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP Quin_alc_DH_like UniProtKB/TrEMBL
  SSF50978 UniProtKB/TrEMBL
UniProt A0A0G2K2Z0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y0M9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A8G5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ALM1 ENTREZGENE, UniProtKB/TrEMBL
  A6H9N0 ENTREZGENE, UniProtKB/TrEMBL
  A6H9N1 ENTREZGENE, UniProtKB/TrEMBL
  F1LT71 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-12-04 Eml4  EMAP like 4  Eml4  echinoderm microtubule associated protein like 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Eml4  echinoderm microtubule associated protein like 4   Eml4_predicted  echinoderm microtubule associated protein like 4 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Eml4_predicted  echinoderm microtubule associated protein like 4 (predicted)      Symbol and Name status set to approved 70820 APPROVED