Fez2 (fasciculation and elongation protein zeta 2) - Rat Genome Database
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Gene: Fez2 (fasciculation and elongation protein zeta 2) Rattus norvegicus
Analyze
Symbol: Fez2
Name: fasciculation and elongation protein zeta 2
RGD ID: 619709
Description: Predicted to be involved in negative regulation of autophagosome assembly. Predicted to localize to axon and cytoplasm. Orthologous to human FEZ2 (fasciculation and elongation protein zeta 2); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,4-dinitrotoluene; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: fasciculation and elongation protein zeta 2 (zygin II); fasciculation and elongation protein zeta-2; MGC112579; synaptotagmin interacting protein zyginII; Zrp; zygin II; zygin-2; zygin-related protein; zygin-related protein types I/II
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.06963,903 - 1,003,955 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6963,907 - 1,004,001 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06955,729 - 995,477 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.461,145,261 - 1,184,406 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.161,145,359 - 1,184,406 (-)NCBI
Celera616,298,245 - 16,337,422 (+)NCBICelera
Cytogenetic Map6q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
axon  (IBA)
cytoplasm  (IBA)

Molecular Function

References

Additional References at PubMed
PMID:12477932   PMID:14697253   PMID:25495476  


Genomics

Comparative Map Data
Fez2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.06963,903 - 1,003,955 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6963,907 - 1,004,001 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06955,729 - 995,477 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.461,145,261 - 1,184,406 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.161,145,359 - 1,184,406 (-)NCBI
Celera616,298,245 - 16,337,422 (+)NCBICelera
Cytogenetic Map6q11NCBI
FEZ2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl236,531,805 - 36,646,087 (-)EnsemblGRCh38hg38GRCh38
GRCh38236,552,239 - 36,598,190 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37236,779,397 - 36,825,333 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36236,632,905 - 36,678,836 (-)NCBINCBI36hg18NCBI36
Build 34236,691,056 - 36,736,886NCBI
Celera236,620,493 - 36,666,401 (-)NCBI
Cytogenetic Map2p22.2NCBI
HuRef236,519,688 - 36,565,600 (-)NCBIHuRef
CHM1_1236,708,760 - 36,754,691 (-)NCBICHM1_1
Fez2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391778,676,641 - 78,725,581 (-)NCBIGRCm39mm39
GRCm381778,369,212 - 78,418,152 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1778,369,212 - 78,418,152 (-)EnsemblGRCm38mm10GRCm38
MGSCv371778,777,225 - 78,817,443 (-)NCBIGRCm37mm9NCBIm37
MGSCv361778,282,943 - 78,323,161 (-)NCBImm8
Celera1782,679,824 - 82,720,044 (-)NCBICelera
Cytogenetic Map17E2- E3NCBI
cM Map1748.57NCBI
Fez2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554414,421,936 - 4,456,070 (-)NCBIChiLan1.0ChiLan1.0
FEZ2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A37,344,067 - 37,390,521 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A37,344,973 - 37,390,525 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A36,581,436 - 36,628,054 (-)NCBIMhudiblu_PPA_v0panPan3
FEZ2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1729,044,355 - 29,086,100 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11729,043,449 - 29,086,104 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Fez2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366631,576,311 - 1,637,363 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FEZ2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3103,566,221 - 103,615,775 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13103,566,214 - 103,612,855 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23110,211,643 - 110,257,184 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FEZ2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl1470,822,885 - 70,865,129 (+)Ensembl
ChlSab1.11470,822,793 - 70,899,025 (+)NCBI
Fez2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473818,217,238 - 18,260,096 (-)NCBI

Position Markers
D6Rat179  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.06985,684 - 985,932NCBIRnor6.0
Rnor_5.06977,509 - 977,757UniSTSRnor5.0
RGSC_v3.461,166,225 - 1,166,473UniSTSRGSC3.4
RGSC_v3.161,165,971 - 1,166,643RGD
Celera616,316,207 - 16,316,455UniSTS
Cytogenetic Map6q11UniSTS
FHH x ACI Map618.28UniSTS
FHH x ACI Map618.28RGD
RH134470  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.06963,924 - 964,124NCBIRnor6.0
Rnor_5.06955,749 - 955,949UniSTSRnor5.0
RGSC_v3.461,144,535 - 1,144,735UniSTSRGSC3.4
Celera616,337,948 - 16,338,148UniSTS
Cytogenetic Map6q11UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6123620518Rat
1578758Tcas9Tongue tumor susceptibility QTL 93.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)6125048718Rat
738023Alc17Alcohol consumption QTL 173.10.003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)6135623029Rat
1354616Despr12Despair related QTL 120.0012locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)6135623029Rat
1549905Stresp10Stress response QTL 106.830.0066stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)6135623029Rat
2300176Bmd51Bone mineral density QTL 5111.70.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)6135623029Rat
2300190Bmd52Bone mineral density QTL 5211.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)6135623029Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)6141917988Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6142388212Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6142388212Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6142388212Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6142388212Rat
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6142388212Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6143665660Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6143665660Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6143665660Rat
7411584Foco4Food consumption QTL 44.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6144015370Rat
738024Sach5Saccharine consumption QTL 53.90.00039consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)6144570292Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6175623393Rat
8693645Alc31Alcohol consumption QTL 313.70.038drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)613505323600274Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:57
Count of miRNA genes:54
Interacting mature miRNAs:56
Transcripts:ENSRNOT00000042735
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 45 35 13 35 8 11 74 35 34 11 8
Low 12 6 6 6 7
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_592821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AABR07062633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01041959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AAHX01041960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB076183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB080086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF120109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF120110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF120111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC100060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB725415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK359698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U64689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000042735   ⟹   ENSRNOP00000049923
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl6964,551 - 1,004,001 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000082071   ⟹   ENSRNOP00000075253
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl6963,907 - 1,003,905 (-)Ensembl
RefSeq Acc Id: NM_053600   ⟹   NP_446052
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06964,650 - 1,003,924 (-)NCBI
Rnor_5.06955,729 - 995,477 (-)NCBI
RGSC_v3.461,145,261 - 1,184,406 (-)RGD
Celera616,298,245 - 16,337,422 (+)RGD
Sequence:
RefSeq Acc Id: XM_006239637   ⟹   XP_006239699
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06963,903 - 1,003,955 (-)NCBI
Rnor_5.06955,729 - 995,477 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239638   ⟹   XP_006239700
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06963,906 - 1,003,954 (-)NCBI
Rnor_5.06955,729 - 995,477 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239639   ⟹   XP_006239701
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06983,462 - 1,003,955 (-)NCBI
Rnor_5.06955,729 - 995,477 (-)NCBI
Sequence:
RefSeq Acc Id: XR_592821
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06970,026 - 1,003,955 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_446052   ⟸   NM_053600
- UniProtKB: P97578 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006239700   ⟸   XM_006239638
- Peptide Label: isoform X2
- UniProtKB: Q498V3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239699   ⟸   XM_006239637
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006239701   ⟸   XM_006239639
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000075253   ⟸   ENSRNOT00000082071
RefSeq Acc Id: ENSRNOP00000049923   ⟸   ENSRNOT00000042735

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694359
Promoter ID:EPDNEW_R4875
Type:multiple initiation site
Name:Fez2_1
Description:fasciculation and elongation protein zeta 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.061,003,913 - 1,003,973EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619709 AgrOrtholog
Ensembl Genes ENSRNOG00000004577 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000049923 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000075253 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000042735 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000082071 ENTREZGENE, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7128839 IMAGE-MGC_LOAD
InterPro FEZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FEZ_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:94269 UniProtKB/Swiss-Prot
MGC_CLONE MGC:112579 IMAGE-MGC_LOAD
NCBI Gene 94269 ENTREZGENE
PANTHER PTHR12394 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12394:SF11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FEZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fez2 PhenoGen
UniGene Rn.8714 ENTREZGENE
UniProt F7EYQ2_RAT UniProtKB/TrEMBL
  FEZ2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q498V3 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q76LN1 UniProtKB/Swiss-Prot
  Q9JJ35 UniProtKB/Swiss-Prot
  Q9JJ36 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-20 Fez2  fasciculation and elongation protein zeta 2  Fez2  fasciculation and elongation protein zeta 2 (zygin II)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-04-17 Fez2  fasciculation and elongation protein zeta 2 (zygin II)  Zrp  zygin-related protein  Data Merged 737654 PROVISIONAL
2004-02-26 Fez2  fasciculation and elongation protein zeta 2 (zygin II)      Symbol and Name status set to approved 625702 APPROVED
2003-02-27 Zrp  zygin-related protein      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-08-07 Fez2  fasciculation and elongation protein zeta 2 (zygin II)      Symbol and Name status set to provisional 70820 PROVISIONAL