Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Atl2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ATL2 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | affects expression | ISO | Atl2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine affects the expression of ATL2 mRNA | CTD | PMID:22206623 | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of ATL2 mRNA | CTD | PMID:32145629 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | ATL2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ATL2 mRNA | CTD | PMID:21215274 and PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ATL2 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Atl2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ATL2 mRNA | CTD | PMID:24680724 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Atl2 (Mus musculus) | 6480464 | AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ATL2 mRNA] | CTD | PMID:15034205 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Atl2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ATL2 mRNA | CTD | PMID:15034205 | 2,4,6-tribromophenol | decreases expression | ISO | ATL2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 3,3',4,4'-tetrachlorobiphenyl | multiple interactions | ISO | Atl2 (Mus musculus) | 6480464 | 3 more ... | CTD | PMID:19467301 | 4,4'-diaminodiphenylmethane | affects expression | ISO | Atl2 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane affects the expression of ATL2 mRNA | CTD | PMID:18648102 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Atl2 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of ATL2 mRNA | CTD | PMID:28973697 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of ATL2 mRNA | CTD | PMID:31881176 | acrylamide | affects expression | EXP | | 6480464 | Acrylamide affects the expression of ATL2 mRNA | CTD | PMID:28959563 | all-trans-retinoic acid | decreases expression | ISO | ATL2 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of ATL2 mRNA | CTD | PMID:33167477 | antirheumatic drug | increases expression | ISO | ATL2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of ATL2 mRNA | CTD | PMID:24449571 | asbestos | affects expression | ISO | ATL2 (Homo sapiens) | 6480464 | Asbestos affects the expression of ATL2 mRNA | CTD | PMID:17297452 | atrazine | increases expression | ISO | ATL2 (Homo sapiens) | 6480464 | Atrazine results in increased expression of ATL2 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | decreases expression | ISO | Atl2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ATL2 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | increases expression | ISO | Atl2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of ATL2 mRNA | CTD | PMID:15034205 more ... | benzo[a]pyrene | multiple interactions | ISO | Atl2 (Mus musculus) | 6480464 | AHR protein inhibits the reaction [Benzo(a)pyrene results in increased expression of ATL2 mRNA] | CTD | PMID:15034205 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | ATL2 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 and PMID:20382639 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ATL2 mRNA | CTD | PMID:25181051 and PMID:32145629 | bisphenol A | increases expression | ISO | ATL2 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of ATL2 protein | CTD | PMID:34186270 | bisphenol A | multiple interactions | ISO | ATL2 (Homo sapiens) | 6480464 | [ginger extract results in increased abundance of Oils and Volatile] inhibits the reaction [bisphenol A results in decreased expression of ATL2 protein] | CTD | PMID:33376534 | bisphenol A | decreases expression | ISO | ATL2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of ATL2 protein | CTD | PMID:31675489 more ... | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of ATL2 gene | CTD | PMID:28505145 | buspirone | increases expression | EXP | | 6480464 | Buspirone results in increased expression of ATL2 mRNA | CTD | PMID:24136188 | cadmium atom | multiple interactions | ISO | Atl2 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATL2 mRNA | CTD | PMID:37325564 | cadmium dichloride | multiple interactions | ISO | Atl2 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATL2 mRNA | CTD | PMID:37325564 | caffeine | decreases phosphorylation | ISO | ATL2 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of ATL2 protein | CTD | PMID:35688186 | carbamazepine | affects expression | ISO | ATL2 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of ATL2 mRNA | CTD | PMID:25979313 | carbon nanotube | increases expression | ISO | Atl2 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | clofibrate | decreases expression | ISO | Atl2 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of ATL2 mRNA | CTD | PMID:17585979 | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ATL2 mRNA | CTD | PMID:17602206 | copper atom | multiple interactions | ISO | Atl2 (Mus musculus) | 6480464 | [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of ATL2 mRNA | CTD | PMID:15467011 | copper(0) | multiple interactions | ISO | Atl2 (Mus musculus) | 6480464 | [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of ATL2 mRNA | CTD | PMID:15467011 | copper(II) sulfate | decreases expression | ISO | ATL2 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of ATL2 mRNA | CTD | PMID:19549813 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of ATL2 mRNA | CTD | PMID:26577399 | cyclosporin A | decreases expression | ISO | Atl2 (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of ATL2 mRNA | CTD | PMID:19770486 | cyclosporin A | decreases expression | ISO | ATL2 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of ATL2 mRNA | CTD | PMID:25562108 | decabromodiphenyl ether | increases expression | ISO | ATL2 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in increased expression of ATL2 protein | CTD | PMID:31675489 | dibutyl phthalate | increases expression | ISO | Atl2 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of ATL2 mRNA | CTD | PMID:17361019 and PMID:21266533 | doxorubicin | decreases expression | ISO | ATL2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of ATL2 mRNA | CTD | PMID:29803840 | ethanol | affects expression | ISO | Atl2 (Mus musculus) | 6480464 | Ethanol affects the expression of ATL2 mRNA | CTD | PMID:30319688 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of ATL2 mRNA | CTD | PMID:33387578 | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of ATL2 mRNA | CTD | PMID:24136188 | gold atom | decreases expression | ISO | ATL2 (Homo sapiens) | 6480464 | Gold results in decreased expression of ATL2 mRNA | CTD | PMID:25523186 | gold(0) | decreases expression | ISO | ATL2 (Homo sapiens) | 6480464 | Gold results in decreased expression of ATL2 mRNA | CTD | PMID:25523186 | hexane | decreases methylation | EXP | | 6480464 | n-hexane results in decreased methylation of ATL2 promoter | CTD | PMID:23740543 | hydrogen cyanide | decreases expression | ISO | Atl2 (Mus musculus) | 6480464 | Hydrogen Cyanide results in decreased expression of ATL2 mRNA | CTD | PMID:33914522 | inulin | multiple interactions | ISO | Atl2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of ATL2 mRNA | CTD | PMID:36331819 | irinotecan | increases expression | ISO | ATL2 (Homo sapiens) | 6480464 | Irinotecan analog results in increased expression of ATL2 mRNA | CTD | PMID:18927307 | ivermectin | increases expression | ISO | ATL2 (Homo sapiens) | 6480464 | Ivermectin results in increased expression of ATL2 protein | CTD | PMID:32959892 | methotrexate | affects expression | ISO | Atl2 (Mus musculus) | 6480464 | Methotrexate affects the expression of ATL2 mRNA | CTD | PMID:18502557 | methyl methanesulfonate | decreases expression | ISO | ATL2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of ATL2 mRNA | CTD | PMID:23649840 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ATL2 mRNA | CTD | PMID:17602206 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of ATL2 mRNA | CTD | PMID:24136188 | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of ATL2 mRNA | CTD | PMID:24136188 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ATL2 mRNA | CTD | PMID:25729387 | oxaliplatin | decreases expression | EXP | | 6480464 | oxaliplatin results in decreased expression of ATL2 mRNA | CTD | PMID:25729387 | paracetamol | affects expression | ISO | Atl2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of ATL2 mRNA | CTD | PMID:17562736 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Atl2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ATL2 mRNA more ... | CTD | PMID:36331819 | perfluorooctanoic acid | decreases expression | ISO | ATL2 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of ATL2 protein | CTD | PMID:26879310 | phenobarbital | increases expression | ISO | Atl2 (Mus musculus) | 6480464 | Phenobarbital results in increased expression of ATL2 mRNA | CTD | PMID:19270015 | phenobarbital | affects expression | ISO | Atl2 (Mus musculus) | 6480464 | Phenobarbital affects the expression of ATL2 mRNA | CTD | PMID:23091169 | pirinixic acid | increases expression | ISO | Atl2 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of ATL2 mRNA | CTD | PMID:18445702 | potassium cyanide | increases expression | ISO | Atl2 (Mus musculus) | 6480464 | Potassium Cyanide results in increased expression of ATL2 mRNA | CTD | PMID:33914522 | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Atl2 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of ATL2 mRNA | CTD | PMID:28903501 | quercetin | increases expression | ISO | ATL2 (Homo sapiens) | 6480464 | Quercetin results in increased expression of ATL2 mRNA | CTD | PMID:21632981 | quercetin | increases phosphorylation | ISO | ATL2 (Homo sapiens) | 6480464 | Quercetin results in increased phosphorylation of ATL2 protein | CTD | PMID:35688186 | resveratrol | increases expression | ISO | Atl2 (Mus musculus) | 6480464 | resveratrol results in increased expression of ATL2 protein | CTD | PMID:25505154 | resveratrol | multiple interactions | ISO | ATL2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of ATL2 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | ATL2 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of ATL2 protein | CTD | PMID:37664457 | temozolomide | increases expression | ISO | ATL2 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of ATL2 mRNA | CTD | PMID:31758290 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of ATL2 mRNA | CTD | PMID:34492290 | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of ATL2 mRNA | CTD | PMID:25729387 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ATL2 mRNA | CTD | PMID:25729387 | troglitazone | decreases expression | ISO | Atl2 (Mus musculus) | 6480464 | troglitazone results in decreased expression of ATL2 mRNA | CTD | PMID:28973697 | tungsten | increases expression | ISO | Atl2 (Mus musculus) | 6480464 | Tungsten results in increased expression of ATL2 mRNA | CTD | PMID:30912803 | tunicamycin | decreases expression | ISO | ATL2 (Homo sapiens) | 6480464 | Tunicamycin results in decreased expression of ATL2 mRNA | CTD | PMID:29453283 | valproic acid | decreases methylation | ISO | ATL2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of ATL2 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | ATL2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ATL2 mRNA | CTD | PMID:25979313 | |