 Gene Ontology Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Cellular Component
Molecular Function
Molecular Pathway Annotations |
Welcome {{ username}}
Message Center
{{ messageCount }} Messages
Watched Genes
{{$index + 1}}. {{ watchedObject.symbol }} (RGD ID:{{watchedObject.rgdId}})
Watched Ontology Terms
{{gene.symbol}}: {{ gene.description }}
Save List to My RGD
| Create Name: | |
| Description: |
|
| Save what matters to you |
| {{ loginError }} |
| Sign in with your RGD account |
| Create New Account | Recover Password |
{{ watchLinkText }}
Select categories you would like to watch. Updates to this gene will be send to {{ username }}
Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
 Gene Annotator (Annotation Distribution) unavailable |
 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
 Gviewer (Genome Viewer) unavailable |
 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
 OLGA (Gene List Generator) unavailable |
 |
Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
|
MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Cellular Component
Molecular Function
Molecular Pathway AnnotationsGene-Chemical Interaction Annotations
|
|
|
Gene Ontology AnnotationsBiological Process
|
|
Cellular Component
|
|
|
Molecular Function
|
|
Molecular Pathway AnnotationsReferences - curated| 1. | Babbey CM, etal., Am J Physiol Renal Physiol. 2010 Sep;299(3):F495-506. doi: 10.1152/ajprenal.00198.2010. Epub 2010 Jun 24. |
| 2. | Chen YT, etal., Proc Natl Acad Sci U S A 1993 Jul 15;90(14):6508-12. |
| 3. | Elferink LA, etal., J Biol Chem 1992 Mar 25;267(9):5768-75. |
| 4. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 5. | Kaddai V, etal., Acta Physiol (Oxf). 2008 Jan;192(1):75-88. |
| 6. | Klip A, etal., Am J Physiol Cell Physiol. 2014 May 15;306(10):C879-86. doi: 10.1152/ajpcell.00069.2014. Epub 2014 Mar 5. |
| 7. | Larance M, etal., Mol Endocrinol. 2008 Feb;22(2):226-33. Epub 2007 Aug 23. |
| 8. | Liu Y, etal., Nat Commun. 2013;4:2005. doi: 10.1038/ncomms3005. |
| 9. | MGD data from the GO Consortium |
| 10. | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 11. | Pavlos NJ, etal., J Neurosci. 2010 Oct 6;30(40):13441-53. doi: 10.1523/JNEUROSCI.0907-10.2010. |
| 12. | RGD automated data pipeline |
| 13. | RGD automated import pipeline for gene-chemical interactions |
| 14. | RGD comprehensive gene curation |
| 15. | Wang T, etal., Dev Cell. 2011 Sep 13;21(3):431-44. doi: 10.1016/j.devcel.2011.07.007. |
| 16. | Watson RT and Pessin JE, Cell Signal. 2007 Nov;19(11):2209-17. Epub 2007 Jun 21. |
| 17. | Zaid H, etal., Biochem J. 2008 Jul 15;413(2):201-15. |
References - uncurated| PubMed | 2732579 11042173 12477932 16641372 17132146 17403373 18504258 19056867 19717423 20458337 20937701 21423176 22908308 23263280 23533145 24006491 24662485 24891604 25468996 27354378 29476059 |
Genomics
Comparative Map Data| Rab10 (Rattus norvegicus - Norway rat) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| RAB10 (Homo sapiens - human) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Rab10 (Mus musculus - house mouse) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Rab10 (Chinchilla lanigera - long-tailed chinchilla) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| RAB10 (Pan paniscus - bonobo/pygmy chimpanzee) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| RAB10 (Canis lupus familiaris - dog) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Rab10 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| RAB10 (Sus scrofa - pig) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| RAB10 (Chlorocebus sabaeus - African green monkey) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Rab10 (Heterocephalus glaber - naked mole-rat) |
No map positions available. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Position Markers| BI283356 |
|
|||||||||||||||||||||||||||||||||||
| BF393954 |
|
|||||||||||||||||||||||||||||||||||
| AU048675 |
|
|||||||||||||||||||||||||||||||||||
| RAB10_1045 |
|
QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
||||||||
Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | 3 | 43 | 57 | 41 | 19 | 41 | 8 | 11 | 74 | 35 | 41 | 11 | 8 |
| Low | |||||||||||||
| Below cutoff |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_017359 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AABR07063299 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AAHX01042368 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01042369 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01042370 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01042371 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01042372 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AY310140 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AY724493 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC070518 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC085744 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH473947 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ231157 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ233488 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| M83677 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | ENSRNOT00000071425 ⟹ ENSRNOP00000065234 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
|
| RefSeq Acc Id: | NM_017359 ⟹ NP_059055 | ||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
|
||||||||||||||||
| Sequence: |
CCGATCCCTTGGGGCTACCGGCGGCGAGCGCCCGAGCCGCTCCTCCCAATGGCGAAGAAGACGThide sequence |
Protein Sequences| Protein RefSeqs | NP_059055 | (Get FASTA) | NCBI Sequence Viewer |
| GenBank Protein | AAA41991 | (Get FASTA) | NCBI Sequence Viewer |
| AAH85744 | (Get FASTA) | NCBI Sequence Viewer | |
| AAP78748 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM03004 | (Get FASTA) | NCBI Sequence Viewer | |
| EDM03005 | (Get FASTA) | NCBI Sequence Viewer | |
| P35281 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_059055 ⟸ NM_017359 |
| - UniProtKB: | Q5RKJ9 (UniProtKB/TrEMBL) |
| - Sequence: |
MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDhide sequence |
| RefSeq Acc Id: | ENSRNOP00000065234 ⟸ ENSRNOT00000071425 |
TranscriptomeStrain Variation
Strain Sequence Variants (Rnor 6.0)
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:620879 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000047088 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000065234 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000071425 | ENTREZGENE, UniProtKB/TrEMBL |
| IMAGE_CLONE | IMAGE:7191921 | IMAGE-MGC_LOAD |
| InterPro | P-loop_NTPase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| Small_GTP-bd_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| Small_GTPase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| KEGG Report | rno:50993 | UniProtKB/TrEMBL |
| MGC_CLONE | MGC:93509 | IMAGE-MGC_LOAD |
| NCBI Gene | 50993 | ENTREZGENE |
| Pfam | Ras | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| PhenoGen | Rab10 | PhenoGen |
| PROSITE | RAB | UniProtKB/Swiss-Prot |
| Superfamily-SCOP | SSF52540 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| TIGRFAMs | small_GTP | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| UniGene | Rn.65864 | ENTREZGENE |
| UniProt | P35281 | ENTREZGENE |
| Q5RKJ9 | ENTREZGENE, UniProtKB/TrEMBL | |
| RAB10_RAT | UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2004-09-10 | Rab10 | RAB10, member RAS oncogene family | ras-related protein rab10 | Name updated | 1299863 | APPROVED | |
| 2002-08-07 | Rab10 | ras-related protein rab10 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_cellular_localization | localized to membranes in the perinuclear region, possibly to the Golgi apparatus | 734514 |
 |
| More on Rab10 | |
|
Alliance Gene |
|
NCBI Gene |
|
Ensembl Gene |
|
|
JBrowse: rn5 rn6 |
|
NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 620879 |
| Created: | 2002-08-06 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-08-20 |
| Status: | ACTIVE |
