Rab10 (RAB10, member RAS oncogene family)

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner VCMap Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Rab10 (RAB10, member RAS oncogene family) Rattus norvegicus

Analyze

Symbol:

Rab10

Name:

RAB10, member RAS oncogene family

RGD ID:

620879

Description:

Enables GDP-dissociation inhibitor binding activity and myosin V binding activity. Involved in Golgi to plasma membrane transport; cellular response to antibiotic; and generation of neurons. Located in several cellular components, including cilium; perinuclear region of cytoplasm; and trans-Golgi network. Is anchored component of synaptic vesicle membrane. Orthologous to human RAB10 (RAB10, member RAS oncogene family); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

Ac1075; ras-related protein Rab-10; ras-related protein rab10

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RAB10 (RAB10, member RAS oncogene family)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Rab10 (RAB10, member RAS oncogene family)	HGNC	NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Rab10 (RAB10, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RAB10 (RAB10, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RAB10 (RAB10, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rab10 (RAB10, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RAB10 (RAB10, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RAB10 (RAB10, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rab10 (RAB10, member RAS oncogene family)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Rab10 (RAB10, member RAS oncogene family)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Homo sapiens (human):	RAB10 (RAB10, member RAS oncogene family)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	rab10 (RAB10, member RAS oncogene family)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	rab-10	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Rab10	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	SEC4	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	6	26,267,081 - 26,319,739 (-)	NCBI
Rnor_6.0 Ensembl	6	27,668,403 - 27,721,120 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	6	27,668,387 - 27,721,120 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	6	37,479,058 - 37,531,622 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.1	6	26,260,312 - 26,297,639	NCBI
Celera	6	25,743,962 - 25,796,212 (-)	NCBI		Celera
Cytogenetic Map	6	q14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-trinitrobenzenesulfonic acid (EXP)

2,4-dinitrotoluene (EXP)

2-methylcholine (ISO)

3H-1,2-dithiole-3-thione (EXP)

4-amino-2,6-dinitrotoluene (EXP)

aconitine (EXP)

aflatoxin B1 (ISO)

ammonium chloride (EXP)

Aroclor 1254 (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP)

carbon nanotube (ISO)

carboplatin (EXP)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dibutyl phthalate (EXP)

dimethylarsinic acid (EXP)

doxorubicin (ISO)

ethanol (EXP,ISO)

finasteride (EXP)

flutamide (EXP)

folic acid (ISO)

gentamycin (EXP)

haloperidol (EXP)

hydrogen peroxide (ISO)

hypochlorous acid (ISO)

methyl methanesulfonate (ISO)

nickel atom (ISO)

ozone (EXP)

paracetamol (EXP,ISO)

resveratrol (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

sulforaphane (ISO)

tetrachloromethane (ISO)

trichloroethene (EXP)

trimellitic anhydride (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

antigen processing and presentation (IEA,ISO)

axonogenesis (IMP)

cellular response to antibiotic (IEP)

cellular response to insulin stimulus (IBA,IEA,ISO,ISS)

endoplasmic reticulum tubular network organization (IEA,ISO,ISS)

endosomal transport (IEA,ISO,ISS)

establishment of neuroblast polarity (IMP)

establishment of protein localization to endoplasmic reticulum membrane (IEA,ISO,ISS)

establishment of protein localization to membrane (ISO)

Golgi to plasma membrane protein transport (ISO,ISS)

Golgi to plasma membrane transport (IMP)

polarized epithelial cell differentiation (ISO,ISS)

protein localization to basolateral plasma membrane (ISO,ISS)

protein localization to plasma membrane (IBA,IEA,ISO,ISS)

protein secretion (IBA)

regulated exocytosis (IEA,ISO)

regulation of exocytosis (IBA)

vesicle docking involved in exocytosis (IBA)

vesicle-mediated transport (ISO,ISS)

Cellular Component

anchored component of synaptic vesicle membrane (EXP,IDA,IMP)

cilium (IDA,IEA,ISO)

endoplasmic reticulum membrane (IEA,ISO,ISS)

endoplasmic reticulum tubular network (IEA,ISO,ISS)

endosome (IBA,ISO,ISS)

exocyst (ISO,ISS)

exocytic vesicle (IEA,ISO)

Golgi apparatus (IBA,IEA,ISO,ISS)

insulin-responsive compartment (IBA,IEA,ISO,ISS)

membrane (IDA)

perinuclear region of cytoplasm (IDA,IEA,ISO)

phagocytic vesicle membrane (IEA)

plasma membrane (IBA,IEA,ISO,ISS)

recycling endosome (IBA,IEA,ISO,ISS)

recycling endosome membrane (IEA)

synaptic vesicle (IBA)

trans-Golgi network (IDA,ISO)

Molecular Function

G protein activity (IEA)

GDP binding (IEA,ISO,ISS)

GDP-dissociation inhibitor binding (IPI)

GTP binding (IEA,ISO,ISS)

GTPase activity (IEA)

myosin V binding (IEA,IPI,ISO)

protein binding (IPI,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

insulin responsive facilitative sugar transporter mediated glucose transport pathway (ISO)

Rab family mediated signaling pathway (ISO)

References

References - curated


1.	Babbey CM, etal., Am J Physiol Renal Physiol. 2010 Sep;299(3):F495-506. doi: 10.1152/ajprenal.00198.2010. Epub 2010 Jun 24.
2.	Chen YT, etal., Proc Natl Acad Sci U S A 1993 Jul 15;90(14):6508-12.
3.	Elferink LA, etal., J Biol Chem 1992 Mar 25;267(9):5768-75.
4.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5.	Kaddai V, etal., Acta Physiol (Oxf). 2008 Jan;192(1):75-88.
6.	Klip A, etal., Am J Physiol Cell Physiol. 2014 May 15;306(10):C879-86. doi: 10.1152/ajpcell.00069.2014. Epub 2014 Mar 5.
7.	Larance M, etal., Mol Endocrinol. 2008 Feb;22(2):226-33. Epub 2007 Aug 23.
8.	Liu Y, etal., Nat Commun. 2013;4:2005. doi: 10.1038/ncomms3005.
9.	MGD data from the GO Consortium
10.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
11.	Pavlos NJ, etal., J Neurosci. 2010 Oct 6;30(40):13441-53. doi: 10.1523/JNEUROSCI.0907-10.2010.
12.	RGD automated data pipeline
13.	RGD automated import pipeline for gene-chemical interactions
14.	RGD comprehensive gene curation
15.	Wang T, etal., Dev Cell. 2011 Sep 13;21(3):431-44. doi: 10.1016/j.devcel.2011.07.007.
16.	Watson RT and Pessin JE, Cell Signal. 2007 Nov;19(11):2209-17. Epub 2007 Jun 21.
17.	Zaid H, etal., Biochem J. 2008 Jul 15;413(2):201-15.

Additional References at PubMed

PMID:2732579	PMID:11042173	PMID:12477932	PMID:16641372	PMID:17132146	PMID:17403373	PMID:18504258	PMID:19056867	PMID:19717423	PMID:20458337	PMID:20937701	PMID:21423176
PMID:22908308	PMID:23263280	PMID:23533145	PMID:24006491	PMID:24662485	PMID:24891604	PMID:25468996	PMID:27354378	PMID:29476059	PMID:31505169

Genomics

Comparative Map Data

Rab10
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	6	26,267,081 - 26,319,739 (-)	NCBI
Rnor_6.0 Ensembl	6	27,668,403 - 27,721,120 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	6	27,668,387 - 27,721,120 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	6	37,479,058 - 37,531,622 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.1	6	26,260,312 - 26,297,639	NCBI
Celera	6	25,743,962 - 25,796,212 (-)	NCBI		Celera
Cytogenetic Map	6	q14	NCBI

RAB10
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	2	26,034,084 - 26,137,454 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	2	26,034,084 - 26,137,454 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	2	26,256,953 - 26,360,323 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	26,110,478 - 26,213,782 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	2	26,168,624 - 26,271,929	NCBI
Celera	2	26,097,002 - 26,200,567 (+)	NCBI
Cytogenetic Map	2	p23.3	NCBI
HuRef	2	25,993,019 - 26,096,921 (+)	NCBI		HuRef
CHM1_1	2	26,186,807 - 26,290,405 (+)	NCBI		CHM1_1

Rab10
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	3,297,428 - 3,359,969 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	12	3,297,428 - 3,359,969 (-)	Ensembl
GRCm38	12	3,247,428 - 3,309,969 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	3,247,428 - 3,309,969 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	3,247,428 - 3,309,969 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	12	3,247,726 - 3,309,939 (-)	NCBI			mm8
Celera	12	3,174,851 - 3,237,418 (-)	NCBI		Celera
Cytogenetic Map	12	A1.1	NCBI
cM Map	12	1.71	NCBI

Rab10
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955469	8,057,235 - 8,138,983 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955469	8,057,235 - 8,138,983 (+)	NCBI	ChiLan1.0	ChiLan1.0

RAB10
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	2A	26,125,984 - 26,228,505 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	26,125,985 - 26,228,505 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	2A	26,034,046 - 26,132,658 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

RAB10
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	20,181,363 - 20,264,927 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	20,181,363 - 20,264,927 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	20,077,187 - 20,160,857 (+)	NCBI
ROS_Cfam_1.0	17	20,503,635 - 20,587,796 (+)	NCBI
UMICH_Zoey_3.1	17	20,190,180 - 20,274,283 (+)	NCBI
UNSW_CanFamBas_1.0	17	20,200,321 - 20,284,230 (+)	NCBI
UU_Cfam_GSD_1.0	17	20,247,131 - 20,331,947 (+)	NCBI

Rab10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	64,488,453 - 64,575,695 (+)	NCBI
SpeTri2.0	NW_004936493	6,263,870 - 6,351,327 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RAB10
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	112,828,879 - 112,924,269 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	112,842,190 - 112,924,188 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	119,827,428 - 119,909,414 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RAB10
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	81,508,800 - 81,618,172 (-)	NCBI
ChlSab1.1 Ensembl	14	81,507,031 - 81,617,983 (-)	Ensembl
Vero_WHO_p1.0	NW_023666045	30,540,276 - 30,649,087 (+)	NCBI

Rab10
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624738	8,212,401 - 8,294,307 (+)	NCBI

Position Markers

BI283356

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	26,267,200 - 26,267,405 (+)	MAPPER
Rnor_6.0	6	27,668,507 - 27,668,711	NCBI	Rnor6.0
Rnor_5.0	6	37,479,178 - 37,479,382	UniSTS	Rnor5.0
Celera	6	25,744,082 - 25,744,286	UniSTS
RH 3.4 Map	6	118.2	UniSTS
Cytogenetic Map	6	q12	UniSTS

BF393954

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	26,285,386 - 26,285,553 (+)	MAPPER
Rnor_6.0	6	27,686,682 - 27,686,848	NCBI	Rnor6.0
Rnor_5.0	6	37,497,184 - 37,497,350	UniSTS	Rnor5.0
RGSC_v3.4	6	26,257,916 - 26,258,082	UniSTS	RGSC3.4
Celera	6	25,761,930 - 25,762,096	UniSTS
RH 3.4 Map	6	118.19	UniSTS
Cytogenetic Map	6	q12	UniSTS

AU048675

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	26,313,990 - 26,314,190 (+)	MAPPER
Rnor_6.0	6	27,715,372 - 27,715,571	NCBI	Rnor6.0
Rnor_5.0	6	37,525,874 - 37,526,073	UniSTS	Rnor5.0
RGSC_v3.4	6	26,288,785 - 26,288,984	UniSTS	RGSC3.4
Celera	6	25,790,473 - 25,790,661	UniSTS
Cytogenetic Map	6	q12	UniSTS

RAB10_1045

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	26,266,838 - 26,267,720 (+)	MAPPER
Rnor_6.0	6	27,668,145 - 27,669,026	NCBI	Rnor6.0
Rnor_5.0	6	37,478,816 - 37,479,697	UniSTS	Rnor5.0
Celera	6	25,743,720 - 25,744,601	UniSTS
Cytogenetic Map	6	q12	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
738023	Alc17	Alcohol consumption QTL 17	3.1	0.003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	6	1	35623029	Rat
1354616	Despr12	Despair related QTL 12		0.0012	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	6	1	35623029	Rat
1549905	Stresp10	Stress response QTL 10	6.83	0.0066	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	6	1	35623029	Rat
2300176	Bmd51	Bone mineral density QTL 51	11.7	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	6	1	35623029	Rat
2300190	Bmd52	Bone mineral density QTL 52	11.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	6	1	35623029	Rat
1331743	Uae28	Urinary albumin excretion QTL 28	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	1	41917988	Rat
9589048	Scfw3	Subcutaneous fat weight QTL 3	4.57	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	6	1	42388212	Rat
9589129	Insul24	Insulin level QTL 24	19.06	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	6	1	42388212	Rat
7411603	Foco13	Food consumption QTL 13	5.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1	42388212	Rat
7411542	Bw127	Body weight QTL 127	5.5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	1	42388212	Rat
8552962	Pigfal16	Plasma insulin-like growth factor 1 level QTL 16	9.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	6	1	42388212	Rat
2293709	Bss23	Bone structure and strength QTL 23	5.18	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	6	1	43665660	Rat
2293650	Bss31	Bone structure and strength QTL 31	5.05	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	6	1	43665660	Rat
2293656	Bss28	Bone structure and strength QTL 28	6.79	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	6	1	43665660	Rat
7411584	Foco4	Food consumption QTL 4	4.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1	44015370	Rat
738024	Sach5	Saccharine consumption QTL 5	3.9	0.00039	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	6	1	44570292	Rat
2301972	Bp325	Blood pressure QTL 325	4.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	1	75623393	Rat
1359023	Bp272	Blood pressure QTL 272	2.5		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	1120393	28706721	Rat
2292589	Emca10	Estrogen-induced mammary cancer QTL 10		0.048	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	6	1120393	46120393	Rat
1354664	Slep2	Serum leptin concentration QTL 2	4.49		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	6	1120393	75023446	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	2537030	111715717	Rat
1578665	Bss16	Bone structure and strength QTL 16	4.4		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	6	6161722	76002731	Rat
1578668	Bmd14	Bone mineral density QTL 14	3.8		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	6	6161722	76002731	Rat
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	7009971	115379601	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	10173862	55173862	Rat
1300128	Rf16	Renal function QTL 16	3.89		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	13122958	34367603	Rat
1300164	Rf15	Renal function QTL 15	3.12		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	13122958	57516539	Rat
10401812	Kidm54	Kidney mass QTL 54			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	16810107	61810107	Rat
10401800	Kidm49	Kidney mass QTL 49			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	16810107	61810107	Rat
8552910	Pigfal5	Plasma insulin-like growth factor 1 level QTL 5	4.3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	6	19417887	64417887	Rat
1641898	Colcr4	Colorectal carcinoma resistance QTL4	3.71	0.0007	intestine integrity trait (VT:0010554)	well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)	6	21515302	65784818	Rat
2293839	Kiddil2	Kidney dilation QTL 2	4.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	22042854	84763421	Rat
2293841	Kiddil4	Kidney dilation QTL 4	4.4		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	22042854	84763421	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	275
Count of miRNA genes:	171
Interacting mature miRNAs:	219
Transcripts:	ENSRNOT00000071425
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	11	74	35	41	11	8
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_017359	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY310140	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY724493	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC070518	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC085744	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ231157	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ233488	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000164	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M83677	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000071425 ⟹ ENSRNOP00000065234

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	6	27,668,403 - 27,721,120 (-)	Ensembl

RefSeq Acc Id:

NM_017359 ⟹ NP_059055

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	26,267,081 - 26,319,739 (-)	NCBI
Rnor_6.0	6	27,668,387 - 27,721,120 (-)	NCBI
Rnor_5.0	6	37,479,058 - 37,531,622 (-)	NCBI
Celera	6	25,743,962 - 25,796,212 (-)	RGD

Sequence:

show sequence

CCGATCCCTTGGGGCTACCGGCGGCGAGCGCCCGAGCCGCTCCTCCCAATGGCGAAGAAGACGT
ACGACCTGCTTTTCAAGCTGCTCCTGATCGGGGACTCGGGAGTGGGCAAGACCTGCGTCCTTTT
TCGTTTTTCGGATGATGCCTTCAATACCACCTTTATTTCCACCATAGGAATAGACTTTAAGATC
AAAACAGTGGAACTACAAGGAAAGAAGATCAAGCTACAGATATGGGACACAGCAGGCCAGGAAC
GATTTCACACCATCACAACCTCCTACTACAGAGGAGCAATGGGCATCATGCTAGTGTATGACAT
CACCAACGGTAAAAGTTTTGAAAACATCAGCAAGTGGCTTAGAAACATAGATGAGCATGCCAAT
GAAGATGTGGAAAGGATGTTACTAGGGAACAAGTGTGACATGGACGACAAGAGAGTTGTACCGA
AAGGCAAAGGAGAGCAGATTGCAAGGGAGCATGGTATTAGGTTTTTTGAGACTAGTGCAAAAGC
AAATATAAACATCGAAAAGGCGTTCCTCACATTAGCTGAAGACATCCTCCGAAAGACCCCTGTA
AAAGAACCCAACAGTGAAAACGTAGATATCAGCAGTGGAGGAGGTGTGACGGGCTGGAAGAGCA
AATGCTGCTGAGCGCTCTCCCGTCCATCTGTTGCCATCCACCATCCGTTTCTCTTCTTGCTGCA
AAATAAAACACTCTGTCCATTTTTAACTCTAAACAGATATTTTTGTTCCTCATCTTAACTATTC
AGTCCACCTATTTTATTTGTTCTTTCATCTGTGACTGCTTGCGGACTATTATAATTTTCTTCAA
ACAAAAAAAATGTATAGAGAAATCATGTCCGACTTCATTTTCAGATGTTCTTGCTCAGCTCACC
ACTGCACTTCTGTTGTATTATAGTCCAGCTCTTATCAACATTAACTACAGCAATCATTTCAACT
CTATTCTGCAAATTGTATAAGAATAAAAGTTAGAATTAACAATTTTATTTTGTACAACAGTGGG
ATTTTCTGTCATGAATAATGTGCTTGAGTCCTATAACCTATAGATGTGATAGCAAAGAAACACA
AGCCAGGAAAACATTCATTTCCCCTGAATCAGTACGTGGGGTTAATTTTGTCCTGTGCCTTATG
TGGAAAGGAACTACTTTGGTTTCTCTTTTTTGTTCGGTGGAAGCATGTGCAGGAGACATTTCAT
CCCAACATAAACCCGTTCAGATGCTTGTGGTTTGCTTGGCTGTATCTTTCACAGTAGTTAACCG
AGGACAAAGGGTAATGCAGAAGTGATACTTGATTTCCAGTCTCATTCCCAGTGGCCTTGATATT
TAAACTGATTCCCGCCACCAGGTCCTTGGGCCACTCTGTCCCTGCGTCTCATCTTTCTGCATGC
TGCTTTGTTTGCCCCCACTACTCCTGGTATGAGTTATTTAAAAATGAAAGGTTTGTCAAGTTTA
ACATAAAGCACTGATTTACCTTGCTAAGTAAACAGAAAGATAAATTCTAACTGCCTATATCAGA
TGTCAGTTAATCGGTGTCAGCCCCTCATTTACTCTCTCCTAAAACCTGACCCGCAGTTTGCCTT
CTGTTCCCCTCCCCCCTCCTGTCTATCCATGGAGTTTATGAAATGGAAGAGTTATTGCATGCAC
TAGTGTTTGGAGGGTGTTGTGGTTTGTCTCTAATTAGGTGTATATCCTATTCACTTTCCTAGAA
TAAGCCTCTTAACCTGAATGTGACTAGTCTCCATTATGGCGACTCCTCTGGCAGTTCAGTAGCC
CAGGAAAGACTGGTTTTAAAAAGACCATAAAGAGCAAGGAGGAGTGGTCTTAGCGTTTGCCAAA
TGTATTGAGATTTGGCCTCTGAAGAACACTTTCGGTATTGTCTTTACTGTAAGATTTAGAAATA
CATCATAATATTATTAATTTCAAGTCCTATCTTTACATCCTCTCAGAAAACTTATTACCGTGAA
TTTTTTAAAAAAGAAAAAGGACAGCAAAAGGCTTCTCGTGTAAAGCTGAGCTCTCTGGCTCTGT
CCGACCCCATCCTTCTTTCTCTGTTCTAGTTTGGCTTCATTGCTTCTCATTAGGATAGGGTAGG
CGAAGTTCCCTATGCTGCTAGCATCCTAAGATGATACCTTTGTGGAAATAATTGTGAATAGCAT
GATTCATTTCAAGCAGAGGCTGAGTTTAGGACAGCAGCTACCATTGAGAAGATGTCTGTGACAC
GCATTTTAATGACCTCTTGGCTCACATAAACAATATAGGGACATATCTGCTAAAAGAGCCCATG
GTCTTTTCAGATAGTGCCCTAAAGACAATTTTATATGCCTCACTGGTGGTTCTTAGGGTCCCCC
TCACTTGACTCTATCATTGTTTACTAGTAAAAAGCAGCATTGCCAAATAATCCCTGATTTTCCA
CTATGAAAAATGCAATGTCTAAGCTTTTGAAGTTTGTAGGTTAAACCTACTGTTGTTAGTTAGA
TCTTTGCTGTTTGTGTTGCTTCCCTCTATCTGGATTGTGGCGGTCGCCTCTTTACTTTAAACTT
TGTTTAACCCTTAATTCAGTGACTTAAGGTTTGGAGATACACACTGGGATTTTGGCTAACAGAC
TGACAGTTTTGTTGTTTGCATAATTATAATCGGCACTGTACAGAGAAAAGATATGGCCTCCTTT
GTTAAATCTGCACTTTCTGAATATCAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_059055	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA41991	(Get FASTA)	NCBI Sequence Viewer
	AAH85744	(Get FASTA)	NCBI Sequence Viewer
	AAP78748	(Get FASTA)	NCBI Sequence Viewer
	EDM03004	(Get FASTA)	NCBI Sequence Viewer
	EDM03005	(Get FASTA)	NCBI Sequence Viewer
	P35281	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_059055 ⟸ NM_017359

- UniProtKB:

Q5RKJ9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWD
TAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDD
KRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEPNSENVDISSGGGV
TGWKSKCC

hide sequence

RefSeq Acc Id:

ENSRNOP00000065234 ⟸ ENSRNOT00000071425

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620879	AgrOrtholog
Ensembl Genes	ENSRNOG00000047088	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000065234	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000071425	ENTREZGENE, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7191921	IMAGE-MGC_LOAD
InterPro	P-loop_NTPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Small_GTP-bd_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Small_GTPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:50993	UniProtKB/TrEMBL
MGC_CLONE	MGC:93509	IMAGE-MGC_LOAD
NCBI Gene	50993	ENTREZGENE
Pfam	Ras	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Rab10	PhenoGen
PROSITE	RAB	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs	small_GTP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	P35281	ENTREZGENE
	Q5RKJ9	ENTREZGENE, UniProtKB/TrEMBL
	RAB10_RAT	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Rab10	RAB10, member RAS oncogene family		ras-related protein rab10	Name updated	1299863	APPROVED
2002-08-07	Rab10	ras-related protein rab10			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	localized to membranes in the perinuclear region, possibly to the Golgi apparatus	734514

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

RGD Manual Annotations