Rab10 (RAB10, member RAS oncogene family) - Rat Genome Database
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Gene: Rab10 (RAB10, member RAS oncogene family) Mus musculus
Analyze
Symbol: Rab10
Name: RAB10, member RAS oncogene family
RGD ID: 733173
MGI Page MGI
Description: Is expressed in embryo. Orthologous to human RAB10 (RAB10, member RAS oncogene family); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW107754; ras-related protein Rab-10
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39123,297,428 - 3,359,969 (-)NCBIGRCm39mm39
GRCm39 Ensembl123,297,428 - 3,359,969 (-)Ensembl
GRCm38123,247,428 - 3,309,969 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl123,247,428 - 3,309,969 (-)EnsemblGRCm38mm10GRCm38
MGSCv37123,247,428 - 3,309,969 (-)NCBIGRCm37mm9NCBIm37
MGSCv36123,247,726 - 3,309,939 (-)NCBImm8
Celera123,174,851 - 3,237,418 (-)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map121.71NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:8825628   PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11042173   PMID:11076861   PMID:11773082   PMID:11856727   PMID:12477932   PMID:12520002   PMID:12578829  
PMID:14610273   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16512683   PMID:16923123   PMID:17403373   PMID:18076383   PMID:18799693   PMID:19570034   PMID:20576682  
PMID:20643919   PMID:21327095   PMID:21454697   PMID:21677750   PMID:21873635   PMID:22908308   PMID:23375831   PMID:23804653   PMID:24213529   PMID:25860786   PMID:26299925   PMID:26527681  
PMID:27207531   PMID:27354378   PMID:27507650   PMID:28028537   PMID:28132130   PMID:28378742   PMID:28671696   PMID:28706196   PMID:30068389   PMID:30209220   PMID:30333137   PMID:30713523  
PMID:32325033  


Genomics

Comparative Map Data
Rab10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39123,297,428 - 3,359,969 (-)NCBIGRCm39mm39
GRCm39 Ensembl123,297,428 - 3,359,969 (-)Ensembl
GRCm38123,247,428 - 3,309,969 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl123,247,428 - 3,309,969 (-)EnsemblGRCm38mm10GRCm38
MGSCv37123,247,428 - 3,309,969 (-)NCBIGRCm37mm9NCBIm37
MGSCv36123,247,726 - 3,309,939 (-)NCBImm8
Celera123,174,851 - 3,237,418 (-)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map121.71NCBI
RAB10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl226,034,084 - 26,137,454 (+)EnsemblGRCh38hg38GRCh38
GRCh38226,034,084 - 26,137,454 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37226,256,953 - 26,360,323 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36226,110,478 - 26,213,782 (+)NCBINCBI36hg18NCBI36
Build 34226,168,624 - 26,271,929NCBI
Celera226,097,002 - 26,200,567 (+)NCBI
Cytogenetic Map2p23.3NCBI
HuRef225,993,019 - 26,096,921 (+)NCBIHuRef
CHM1_1226,186,807 - 26,290,405 (+)NCBICHM1_1
Rab10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2626,267,081 - 26,319,739 (-)NCBI
Rnor_6.0 Ensembl627,668,403 - 27,721,120 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0627,668,387 - 27,721,120 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0637,479,058 - 37,531,622 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.1626,260,312 - 26,297,639NCBI
Celera625,743,962 - 25,796,212 (-)NCBICelera
Cytogenetic Map6q14NCBI
Rab10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554698,057,235 - 8,138,983 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554698,057,235 - 8,138,983 (+)NCBIChiLan1.0ChiLan1.0
RAB10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A26,125,984 - 26,228,505 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A26,125,985 - 26,228,505 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A26,034,046 - 26,132,658 (+)NCBIMhudiblu_PPA_v0panPan3
RAB10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1720,181,363 - 20,264,927 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11720,181,363 - 20,264,927 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Rab10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364936,263,870 - 6,351,327 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3112,828,879 - 112,924,269 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13112,842,190 - 112,924,188 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23119,827,428 - 119,909,414 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RAB10
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11481,508,800 - 81,618,172 (-)NCBI
ChlSab1.1 Ensembl1481,507,031 - 81,617,983 (-)Ensembl
Rab10
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247388,212,401 - 8,294,307 (+)NCBI

Position Markers
AW107754  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38123,248,749 - 3,248,868UniSTSGRCm38
MGSCv37123,248,749 - 3,248,868UniSTSGRCm37
Celera123,176,172 - 3,176,291UniSTS
Cytogenetic Map12A1.1UniSTS
Whitehead/MRC_RH1224.66UniSTS
BI283356  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3846,450,079 - 6,450,271UniSTSGRCm38
GRCm38123,247,830 - 3,248,022UniSTSGRCm38
MGSCv37123,247,830 - 3,248,022UniSTSGRCm37
MGSCv3746,377,226 - 6,377,418UniSTSGRCm37
Celera123,175,253 - 3,175,445UniSTS
Celera46,367,444 - 6,367,636UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map4A1UniSTS
RH126769  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38123,258,040 - 3,258,288UniSTSGRCm38
MGSCv37123,258,040 - 3,258,288UniSTSGRCm37
Celera123,185,463 - 3,185,711UniSTS
Cytogenetic Map12A1.1UniSTS
cM Map12 UniSTS
cM Map163.5UniSTS
cM MapUN UniSTS
Whitehead/MRC_RH1219.7UniSTS
RAB10_1045  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38123,247,451 - 3,248,340UniSTSGRCm38
MGSCv37123,247,451 - 3,248,340UniSTSGRCm37
Celera123,174,874 - 3,175,763UniSTS
Cytogenetic Map12A1.1UniSTS
AU048675  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38123,303,886 - 3,304,081UniSTSGRCm38
MGSCv37123,303,886 - 3,304,081UniSTSGRCm37
Celera123,231,335 - 3,231,530UniSTS
Cytogenetic Map12A1.1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301393Dyscalc3_mdystrophic cardiac calcinosis 3 (mouse)Not determined12122368579Mouse
1301143Skull17_mskull morphology 17 (mouse)Not determined12122368579Mouse
10402496Lmr22_mleishmaniasis resistance 22 (mouse)Not determined12122368579Mouse
11039525Tbbr2_mTrypanosoma brucei brucei response 2 (mouse)12122368579Mouse
1301655Bmd12_mbone mineral density 12 (mouse)Not determined12124612697Mouse
1357519Vtbt12_mvertebral trabecular bone trait 12 (mouse)Not determined12124612697Mouse
4141296Femwf9_mfemur work to failure 9 (mouse)Not determined127870733Mouse
4141112Tglq2a_mtriglyceride QTL 2a (mouse)Not determined12127870733Mouse
4141436Chldq7_mcholesterol and HDL QTL 7 (mouse)Not determined12127870733Mouse
9850128Tglq5_mtriglyceride QTL 5 (mouse)Not determined12127870733Mouse
12910983Pifs1_mpeptide-induced fatal syndrome 1 (mouse)12130383077Mouse
1301925Ath6_matherosclerosis 6 (mouse)Not determined12132708755Mouse
1301207Circp1_mcircadian photosensitivity 1 (mouse)Not determined12133380338Mouse
4141660Nbwa1_mNZB and NZW autoimmunity 1 (mouse)Not determined1229013334290301Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:922
Count of miRNA genes:498
Interacting mature miRNAs:600
Transcripts:ENSMUST00000021001
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_016676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB232604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC159283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF035646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK134988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC056374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ092612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000021001   ⟹   ENSMUSP00000021001
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl123,247,428 - 3,309,969 (-)Ensembl
RefSeq Acc Id: NM_016676   ⟹   NP_057885
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39123,297,428 - 3,359,969 (-)NCBI
GRCm38123,247,428 - 3,309,969 (-)ENTREZGENE
MGSCv37123,247,428 - 3,309,969 (-)RGD
Celera123,174,851 - 3,237,418 (-)RGD
cM Map12 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_057885   ⟸   NM_016676
- UniProtKB: P61027 (UniProtKB/Swiss-Prot),   Q4FJL0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000021001   ⟸   ENSMUST00000021001

Promoters
RGD ID:6823305
Promoter ID:MM_KWN:11050
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_016676
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36123,309,436 - 3,310,337 (-)MPROMDB
RGD ID:8677800
Promoter ID:EPDNEW_M16931
Type:initiation region
Name:Rab10_2
Description:Mus musculus RAB10, member RAS oncogene family , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M16932  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38123,309,578 - 3,309,638EPDNEW
RGD ID:8677802
Promoter ID:EPDNEW_M16932
Type:initiation region
Name:Rab10_1
Description:Mus musculus RAB10, member RAS oncogene family , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M16931  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38123,309,952 - 3,310,012EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:105066 AgrOrtholog
Ensembl Genes ENSMUSG00000020671 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000021001 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000021001 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:19325 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:105066 ENTREZGENE
NCBI Gene 19325 ENTREZGENE
Pfam Ras UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rab10 PhenoGen
PROSITE RAB UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs small_GTP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt P61027 ENTREZGENE
  Q3U621_MOUSE UniProtKB/TrEMBL
  Q4FJL0 ENTREZGENE, UniProtKB/TrEMBL
  RAB10_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary O88386 UniProtKB/Swiss-Prot
  Q9D7X6 UniProtKB/Swiss-Prot