Gdi1 (GDP dissociation inhibitor 1) - Rat Genome Database

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Gene: Gdi1 (GDP dissociation inhibitor 1) Rattus norvegicus
Analyze
Symbol: Gdi1
Name: GDP dissociation inhibitor 1
RGD ID: 2676
Description: Enables Rab GDP-dissociation inhibitor activity and small GTPase binding activity. Involved in negative regulation of axonogenesis; positive regulation of axon extension; and response to calcium ion. Located in axon; myelin sheath; and neuronal cell body. Part of protein-containing complex. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability; non-syndromic X-linked intellectual disability 41; and psychotic disorder. Orthologous to human GDI1 (GDP dissociation inhibitor 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,4-dibromophenyl 2,4,5-tribromophenyl ether; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GDI-1; GDP-dissociation inhibitor 1; guanosine diphosphate dissociation inhibitor 1; MGC108721; rab GDI alpha; rab GDP dissociation inhibitor alpha
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X152,087,611 - 152,094,274 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX152,087,444 - 152,094,272 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX154,228,737 - 154,235,400 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0X157,791,970 - 157,798,633 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0X155,463,769 - 155,470,432 (+)NCBIRnor_WKY
Rnor_6.0X156,400,734 - 156,407,396 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX156,400,736 - 156,407,404 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01152,140,881 - 152,147,543 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X160,299,115 - 160,305,777 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X160,376,327 - 160,382,037 (-)NCBI
Celera1135,802,481 - 135,809,143 (-)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Cognitive impairment in Gdi1-deficient mice is associated with altered synaptic vesicle pools and short-term synaptic plasticity, and can be corrected by appropriate learning training. Bianchi V, etal., Hum Mol Genet. 2009 Jan 1;18(1):105-17. doi: 10.1093/hmg/ddn321. Epub 2008 Oct 1.
2. Non-specific X-linked semidominant mental retardation by mutations in a Rab GDP-dissociation inhibitor. Bienvenu T, etal., Hum Mol Genet. 1998 Aug;7(8):1311-5.
3. Mutations in GDI1 are responsible for X-linked non-specific mental retardation. D'Adamo P, etal., Nat Genet. 1998 Jun;19(2):134-9.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Antibodies in patients with neuropsychiatric systemic lupus erythematosus. Kimura A, etal., Neurology. 2010 Apr 27;74(17):1372-9. doi: 10.1212/WNL.0b013e3181dad590.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. Molecular cloning and characterization of two rab GDI species from rat brain: brain-specific and ubiquitous types. Nishimura N, etal., J Biol Chem 1994 May 13;269(19):14191-8.
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. Online Mendelian Inheritance in Man, OMIM (TM). Online Mendelian Inheritance in Man, OMIM (TM).
12. Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis. Pavlos NJ, etal., J Neurosci. 2010 Oct 6;30(40):13441-53. doi: 10.1523/JNEUROSCI.0907-10.2010.
13. GOA pipeline RGD automated data pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Rab-alphaGDI activity is regulated by a Hsp90 chaperone complex. Sakisaka T, etal., EMBO J 2002 Nov 15;21(22):6125-35.
17. Cloning, characterization, and expression of a novel GDP dissociation inhibitor isoform from skeletal muscle. Shisheva A, etal., Mol Cell Biol 1994 May;14(5):3459-68.
18. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
19. Novel GDI1 mutation in a large family with nonsyndromic X-linked intellectual disability. Strobl-Wildemann G, etal., Am J Med Genet A. 2011 Dec;155A(12):3067-70. doi: 10.1002/ajmg.a.34291. Epub 2011 Oct 14.
20. Lgl1 activation of rab10 promotes axonal membrane trafficking underlying neuronal polarization. Wang T, etal., Dev Cell. 2011 Sep 13;21(3):431-44. doi: 10.1016/j.devcel.2011.07.007.
21. Two-dimensional electrophoresis with cationic detergents: a powerful tool for the proteomic analysis of myelin proteins. Part 2: analytical aspects. Yamaguchi Y, etal., J Neurosci Res. 2008 Mar;86(4):766-75.
Additional References at PubMed
PMID:10996854   PMID:15166316   PMID:15703388   PMID:17634366   PMID:19910677   PMID:22871113   PMID:23815289   PMID:32357304  


Genomics

Comparative Map Data
Gdi1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X152,087,611 - 152,094,274 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX152,087,444 - 152,094,272 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX154,228,737 - 154,235,400 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0X157,791,970 - 157,798,633 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0X155,463,769 - 155,470,432 (+)NCBIRnor_WKY
Rnor_6.0X156,400,734 - 156,407,396 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX156,400,736 - 156,407,404 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01152,140,881 - 152,147,543 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X160,299,115 - 160,305,777 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X160,376,327 - 160,382,037 (-)NCBI
Celera1135,802,481 - 135,809,143 (-)NCBICelera
Cytogenetic MapXq37NCBI
GDI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X154,437,154 - 154,443,467 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblX154,436,913 - 154,443,467 (+)EnsemblGRCh38hg38GRCh38
GRCh37X153,665,500 - 153,671,814 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,318,715 - 153,325,008 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X153,234,158 - 153,235,516NCBI
CeleraX153,826,304 - 153,832,858 (+)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX142,217,606 - 142,249,463 (+)NCBIHuRef
CHM1_1X153,576,897 - 153,583,451 (+)NCBICHM1_1
T2T-CHM13v2.0X152,673,662 - 152,679,975 (+)NCBIT2T-CHM13v2.0
Gdi1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X73,348,618 - 73,355,473 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX73,348,604 - 73,355,468 (+)EnsemblGRCm39 Ensembl
GRCm38X74,305,012 - 74,311,867 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX74,304,998 - 74,311,862 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X71,550,351 - 71,557,206 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X70,557,976 - 70,564,579 (+)NCBIMGSCv36mm8
CeleraX65,558,803 - 65,565,658 (+)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.97NCBI
Gdi1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955580934,798 - 941,081 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955580935,021 - 941,081 (+)NCBIChiLan1.0ChiLan1.0
GDI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X153,749,661 - 153,755,877 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX153,749,661 - 153,755,877 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X143,878,690 - 143,885,251 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
GDI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X122,141,633 - 122,146,724 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX122,141,566 - 122,146,824 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X125,283,325 - 125,288,416 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX125,256,970 - 125,327,738 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X121,052,346 - 121,057,437 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X123,567,480 - 123,572,571 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X123,329,171 - 123,334,262 (+)NCBIUU_Cfam_GSD_1.0
Gdi1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X119,451,096 - 119,457,045 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049368091,188,793 - 1,194,816 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GDI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX124,960,990 - 124,966,832 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X124,960,835 - 124,966,833 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X143,687,134 - 143,692,968 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GDI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606566,665,274 - 66,671,937 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gdi1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624946902,461 - 909,613 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624946902,831 - 908,815 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
GDI1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X152,093,324 - 152,093,420 (-)MAPPERmRatBN7.2
Rnor_6.0X156,401,588 - 156,401,683NCBIRnor6.0
Rnor_5.01152,141,735 - 152,141,830UniSTSRnor5.0
RGSC_v3.4X160,299,969 - 160,300,064UniSTSRGSC3.4
Celera1135,803,335 - 135,803,430UniSTS
Cytogenetic MapXq37UniSTS
Cytogenetic MapXq37.1-q37.2UniSTS
RH128191  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X152,086,738 - 152,086,948 (-)MAPPERmRatBN7.2
Rnor_6.0X156,408,059 - 156,408,268NCBIRnor6.0
Rnor_5.01152,148,206 - 152,148,415UniSTSRnor5.0
RGSC_v3.4X160,306,440 - 160,306,649UniSTSRGSC3.4
Celera1135,809,806 - 135,810,015UniSTS
Cytogenetic MapXq37UniSTS
Cytogenetic MapXq37.1-q37.2UniSTS
RH134593  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X152,093,920 - 152,094,124 (-)MAPPERmRatBN7.2
Rnor_6.0X156,400,884 - 156,401,087NCBIRnor6.0
Rnor_5.01152,141,031 - 152,141,234UniSTSRnor5.0
RGSC_v3.4X160,299,265 - 160,299,468UniSTSRGSC3.4
Celera1135,802,631 - 135,802,834UniSTS
Cytogenetic MapXq37UniSTS
Cytogenetic MapXq37.1-q37.2UniSTS
ECD07523  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X152,087,732 - 152,088,442 (-)MAPPERmRatBN7.2
Rnor_6.0X156,406,565 - 156,407,274NCBIRnor6.0
Rnor_5.01152,146,712 - 152,147,421UniSTSRnor5.0
RGSC_v3.4X160,304,946 - 160,305,655UniSTSRGSC3.4
Celera1135,808,312 - 135,809,021UniSTS
Cytogenetic MapXq37.1-q37.2UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat
634346Insul4Insulin level QTL 40blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)X126975089152453651Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:93
Count of miRNA genes:78
Interacting mature miRNAs:88
Transcripts:ENSRNOT00000056295
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 4
Medium 3 43 57 41 19 41 8 11 70 35 40 11 8
Low 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000089814   ⟹   ENSRNOP00000070171
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX152,087,444 - 152,094,270 (+)Ensembl
Rnor_6.0 EnsemblX156,400,736 - 156,407,404 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000102658   ⟹   ENSRNOP00000081070
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX152,088,797 - 152,094,272 (+)Ensembl
RefSeq Acc Id: NM_017088   ⟹   NP_058784
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X152,087,611 - 152,094,274 (+)NCBI
Rnor_6.0X156,400,734 - 156,407,396 (-)NCBI
Rnor_5.01152,140,881 - 152,147,543 (-)NCBI
RGSC_v3.4X160,299,115 - 160,305,777 (-)RGD
Celera1135,802,481 - 135,809,143 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_058784   ⟸   NM_017088
- UniProtKB: Q9R274 (UniProtKB/Swiss-Prot),   P50398 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000070171   ⟸   ENSRNOT00000089814
RefSeq Acc Id: ENSRNOP00000081070   ⟸   ENSRNOT00000102658

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P50398-F1-model_v2 AlphaFold P50398 1-447 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13702044
Promoter ID:EPDNEW_R12568
Type:multiple initiation site
Name:Gdi1_1
Description:GDP dissociation inhibitor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X156,407,404 - 156,407,464EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2676 AgrOrtholog
BioCyc Gene G2FUF-629 BioCyc
Ensembl Genes ENSRNOG00000056870 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000070171 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000081070.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000089814 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000102658.1 UniProtKB/TrEMBL
Gene3D-CATH 3.50.50.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7930350 IMAGE-MGC_LOAD
InterPro FAD/NAD-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GDP_dissociation_inhibitor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RabGDI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25183 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124627 IMAGE-MGC_LOAD
NCBI Gene 25183 ENTREZGENE
PANTHER PTHR11787 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GDI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gdi1 PhenoGen
PRINTS RABGDI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RABGDIREP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF51905 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZR55_RAT UniProtKB/TrEMBL
  GDIA_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q5BK95_RAT UniProtKB/TrEMBL
  Q9R274 ENTREZGENE
UniProt Secondary Q499U0 UniProtKB/Swiss-Prot
  Q9R274 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-06-27 Gdi1  GDP dissociation inhibitor 1  Gdi1  guanosine diphosphate dissociation inhibitor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Gdi1  GDP-dissociation inhibitor 1      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction forms a complex with chaperone components Hsp90, Hsc70, and cysteine string protein (CSP) in synaptic membranes 632546