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Gene: Ppp1cb (protein phosphatase 1 catalytic subunit beta) Rattus norvegicus
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Symbol: Ppp1cb
Name: protein phosphatase 1 catalytic subunit beta
RGD ID: 3376
Description: Exhibits phosphoprotein phosphatase activity. Involved in protein dephosphorylation; regulation of glycogen biosynthetic process; and regulation of glycogen catabolic process. Localizes to glycogen granule and protein phosphatase type 1 complex. Predicted to colocalize with nuclear chromosome, telomeric region. Human ortholog(s) of this gene implicated in Noonan syndrome-like disorder with loose anagen hair 2. Orthologous to human PPP1CB (protein phosphatase 1 catalytic subunit beta); PARTICIPATES IN glycogen biosynthetic pathway; glycogen degradation pathway; adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: PP-1B; PP1B; PP1beta; protein phosphatase 1, catalytic subunit, beta isoform; protein phosphatase 1, catalytic subunit, beta isozyme; protein phosphatase-1a; serine/threonine-protein phosphatase PP1-beta catalytic subunit
Orthologs:
Homo sapiens (human) : PPP1CB (protein phosphatase 1 catalytic subunit beta)  HGNC  Alliance
Mus musculus (house mouse) : Ppp1cb (protein phosphatase 1 catalytic subunit beta)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppp1cb (protein phosphatase 1 catalytic subunit beta)
Pan paniscus (bonobo/pygmy chimpanzee) : PPP1CB (protein phosphatase 1 catalytic subunit beta)
Canis lupus familiaris (dog) : PPP1CB (protein phosphatase 1 catalytic subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppp1cb (protein phosphatase 1 catalytic subunit beta)
Sus scrofa (pig) : PPP1CB (protein phosphatase 1 catalytic subunit beta)
Chlorocebus sabaeus (African green monkey) : PPP1CB (protein phosphatase 1 catalytic subunit beta)
Heterocephalus glaber (naked mole-rat) : Ppp1cb (protein phosphatase 1 catalytic subunit beta)
more info ...
Related Pseudogenes: Ppp1cb-ps  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0623,548,507 - 23,581,136 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl623,549,317 - 23,581,052 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0633,416,540 - 33,448,276 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4624,067,544 - 24,099,280 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1624,070,497 - 24,102,233 (-)NCBI
Celera623,460,146 - 23,491,883 (-)NCBICelera
Cytogenetic Map6q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ppp1cb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3376
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.