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Gene: PPP1CB (protein phosphatase 1 catalytic subunit beta) Homo sapiens
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Symbol: PPP1CB
Name: protein phosphatase 1 catalytic subunit beta
Description: Exhibits myosin-light-chain-phosphatase activity and protein kinase binding activity. Involved in regulation of cell adhesion and regulation of circadian rhythm. Localizes to several cellular components, including PTW/PP1 phosphatase complex; cytosol; and nucleoplasm. Colocalizes with nuclear chromosome, telomeric region.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: epididymis secretory sperm binding protein Li 80p; HEL-S-80p; MGC3672; MP; myosin phosphatase; NSLH2; PP-1B; PP1B; PP1beta; PP1c; PPP1beta; PPP1CD; protein phosphatase 1, catalytic subunit, beta isoform; protein phosphatase 1, catalytic subunit, delta isoform; protein phosphatase 1-beta; protein phosphatase 1-delta; serine/threonine protein phosphatase PP1-beta catalytic subunit; serine/threonine-protein phosphatase PP1-beta catalytic subunit
Orthologs:
Mus musculus (house mouse) : Ppp1cb (protein phosphatase 1 catalytic subunit beta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ppp1cb (protein phosphatase 1 catalytic subunit beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppp1cb (protein phosphatase 1 catalytic subunit beta)
Pan paniscus (bonobo/pygmy chimpanzee) : PPP1CB (protein phosphatase 1 catalytic subunit beta)
Canis lupus familiaris (dog) : PPP1CB (protein phosphatase 1 catalytic subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppp1cb (protein phosphatase 1 catalytic subunit beta)
Sus scrofa (pig) : PPP1CB (protein phosphatase 1 catalytic subunit beta)
Chlorocebus sabaeus (African green monkey) : PPP1CB (protein phosphatase 1 catalytic subunit beta)
Heterocephalus glaber (naked mole-rat) : Ppp1cb (protein phosphatase 1 catalytic subunit beta)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl228,751,640 - 28,802,940 (+)EnsemblGRCh38hg38GRCh38
GRCh38228,751,748 - 28,802,940 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37228,974,614 - 29,025,806 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36228,828,118 - 28,879,310 (+)NCBINCBI36hg18NCBI36
Build 34228,886,264 - 28,937,456NCBI
Celera228,820,144 - 28,871,300 (+)NCBI
Cytogenetic Map2p23.2NCBI
HuRef228,716,532 - 28,767,764 (+)NCBIHuRef
CHM1_1228,904,700 - 28,955,863 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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References - uncurated

Genomics

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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on PPP1CB
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731669
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.