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Gene: Ppp1cb (protein phosphatase 1 catalytic subunit beta) Mus musculus
Symbol: Ppp1cb
Name: protein phosphatase 1 catalytic subunit beta
Description: Exhibits protein serine/threonine phosphatase activity. Involved in circadian regulation of gene expression; entrainment of circadian clock by photoperiod; and protein dephosphorylation. Localizes to cytoplasm. Predicted to colocalize with nuclear chromosome, telomeric region. Is expressed in cornea; lens epithelium; lens fiber; limb; and retina. Human ortholog(s) of this gene implicated in Noonan syndrome-like disorder with loose anagen hair 2. Orthologous to human PPP1CB (protein phosphatase 1 catalytic subunit beta); PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; dopamine signaling pathway; glycogen biosynthetic pathway; INTERACTS WITH 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 7,12-dimethyltetraphene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1200010B19; PP-1B; serine/threonine-protein phosphatase PP1-beta catalytic subunit
Homo sapiens (human) : PPP1CB (protein phosphatase 1 catalytic subunit beta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ppp1cb (protein phosphatase 1 catalytic subunit beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppp1cb (protein phosphatase 1 catalytic subunit beta)
Pan paniscus (bonobo/pygmy chimpanzee) : PPP1CB (protein phosphatase 1 catalytic subunit beta)
Canis lupus familiaris (dog) : PPP1CB (protein phosphatase 1 catalytic subunit beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppp1cb (protein phosphatase 1 catalytic subunit beta)
Sus scrofa (pig) : PPP1CB (protein phosphatase 1 catalytic subunit beta)
Chlorocebus sabaeus (African green monkey) : PPP1CB (protein phosphatase 1 catalytic subunit beta)
Heterocephalus glaber (naked mole-rat) : Ppp1cb (protein phosphatase 1 catalytic subunit beta)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl532,458,843 - 32,517,433 (+)EnsemblGRCm38mm10GRCm38
GRCm38532,458,848 - 32,493,713 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37532,761,343 - 32,796,085 (+)NCBIGRCm37mm9NCBIm37
MGSCv36532,735,841 - 32,769,335 (+)NCBImm8
Celera529,932,959 - 29,967,634 (+)NCBICelera
Cytogenetic Map5B1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Ppp1cb
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731670
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.