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Gene: Six2 (SIX homeobox 2) Rattus norvegicus
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Symbol: Six2
Name: SIX homeobox 2
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and transcription factor binding activity. Predicted to be involved in several processes, including animal organ development; condensed mesenchymal cell proliferation; and regulation of transcription, DNA-templated. Predicted to localize to the nucleus and transcription factor complex. Orthologous to human SIX2 (SIX homeobox 2); INTERACTS WITH bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog); 4,4'-diaminodiphenylmethane (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: homeobox protein SIX2; LOC366542; sine oculis-related homeobox 2 homolog; sine oculis-related homeobox 2 homolog (Drosophila)
Orthologs:
Homo sapiens (human) : SIX2 (SIX homeobox 2)  HGNC  Alliance
Mus musculus (house mouse) : Six2 (sine oculis-related homeobox 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Six2 (SIX homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SIX2 (SIX homeobox 2)
Canis lupus familiaris (dog) : SIX2 (SIX homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Six2 (SIX homeobox 2)
Sus scrofa (pig) : SIX2 (SIX homeobox 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.068,952,572 - 8,955,893 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.068,875,432 - 8,878,685 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.469,094,655 - 9,097,973 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.169,095,089 - 9,098,000 (-)NCBI
Celera68,702,767 - 8,705,759 (+)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Six2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310792
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.