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Gene: Cox7a2l (cytochrome c oxidase subunit 7A2 like) Rattus norvegicus

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Symbol:

Cox7a2l

Name:

cytochrome c oxidase subunit 7A2 like

RGD ID:

1306111

Description:

Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in mitochondrial respirasome assembly. Predicted to be located in nucleolus. Predicted to be part of respiratory chain complex. Predicted to be active in mitochondrial inner membrane. Orthologous to human COX7A2L (cytochrome c oxidase subunit 7A2 like); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

cytochrome c oxidase subunit VIIa polypeptide 2 like; LOC298762

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	COX7A2L (cytochrome c oxidase subunit 7A2 like)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Cox7a2l (cytochrome c oxidase subunit 7A2 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cox7a2l (cytochrome c oxidase subunit 7A2 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	COX7A2L (cytochrome c oxidase subunit 7A2 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	COX7A2L (cytochrome c oxidase subunit 7A2 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cox7a2l (cytochrome c oxidase subunit 7A2 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	COX7A2L (cytochrome c oxidase subunit 7A2 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	COX7A2L (cytochrome c oxidase subunit 7A2 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cox7a2l (cytochrome c oxidase subunit 7A2 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	COX7A2L (cytochrome c oxidase subunit 7A2 like)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Cox7a2l (cytochrome c oxidase subunit 7A2 like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	COX7A	Alliance	DIOPT (InParanoid\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	COX7AL	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG34172	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	cox7a2l	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cox7a2l	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	XB5730115 [provisional]	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	16,936,574 - 16,950,797 (+)	NCBI		GRCr8
mRatBN7.2	6	11,184,064 - 11,198,287 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	11,184,285 - 11,198,273 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	11,478,130 - 11,492,350 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	11,787,460 - 11,801,680 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	11,300,814 - 11,315,039 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	6,695,807 - 6,709,790 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	6,695,827 - 6,709,783 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	6,650,352 - 6,664,329 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	6,834,523 - 6,861,652 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	6,835,178 - 6,861,594 (-)	NCBI
Celera	6	10,889,441 - 10,903,386 (+)	NCBI		Celera
Cytogenetic Map	6	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Lynch syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (ISO)

1,2-dimethylhydrazine (ISO)

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

6-propyl-2-thiouracil (EXP)

arsenite(3-) (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP,ISO)

buspirone (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

carbon nanotube (ISO)

chloropicrin (ISO)

chlorpyrifos (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

daidzein (ISO)

dicrotophos (ISO)

doxorubicin (ISO)

flutamide (ISO)

genistein (ISO)

ivermectin (ISO)

lipopolysaccharide (ISO)

maneb (ISO)

monosodium L-glutamate (ISO)

N,N-diethyl-m-toluamide (EXP)

nicotine (ISO)

ochratoxin A (ISO)

paracetamol (ISO)

paraquat (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

permethrin (EXP)

pirinixic acid (ISO)

Pyridostigmine bromide (EXP)

rotenone (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

tamoxifen (ISO)

testosterone (ISO)

thiram (ISO)

titanium dioxide (ISO)

toluene (EXP)

tributylstannane (EXP)

valproic acid (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

mitochondrial electron transport, cytochrome c to oxygen (IEA)

mitochondrial respirasome assembly (IBA,IEA,ISO)

Cellular Component

membrane (IEA)

mitochondrial inner membrane (IEA,ISO)

mitochondrion (IEA,ISO)

nucleolus (IEA,ISO)

respiratory chain complex (IBA)

respiratory chain complex IV (IEA)

Molecular Function

protein-macromolecule adaptor activity (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

Alzheimer's disease pathway (IEA)

Huntington's disease pathway (IEA)

oxidative phosphorylation pathway (IEA)

Parkinson's disease pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	KEGG: Kyoto Encyclopedia of Genes and Genomes	KEGG
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:12477932	PMID:14651853	PMID:18614015	PMID:23812712	PMID:23857330

Genomics

Comparative Map Data

Cox7a2l
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	16,936,574 - 16,950,797 (+)	NCBI		GRCr8
mRatBN7.2	6	11,184,064 - 11,198,287 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	11,184,285 - 11,198,273 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	11,478,130 - 11,492,350 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	11,787,460 - 11,801,680 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	11,300,814 - 11,315,039 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	6,695,807 - 6,709,790 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	6,695,827 - 6,709,783 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	6,650,352 - 6,664,329 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	6,834,523 - 6,861,652 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	6,835,178 - 6,861,594 (-)	NCBI
Celera	6	10,889,441 - 10,903,386 (+)	NCBI		Celera
Cytogenetic Map	6	q12	NCBI

COX7A2L
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	42,335,559 - 42,368,957 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	42,333,546 - 42,425,088 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	42,562,699 - 42,596,097 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	42,431,146 - 42,441,860 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	42,489,297 - 42,500,007	NCBI
Celera	2	42,417,924 - 42,428,640 (-)	NCBI		Celera
Cytogenetic Map	2	p21	NCBI
HuRef	2	42,312,008 - 42,322,727 (-)	NCBI		HuRef
CHM1_1	2	42,507,075 - 42,517,803 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	42,340,963 - 42,374,398 (-)	NCBI		T2T-CHM13v2.0

Cox7a2l
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	83,809,346 - 83,821,762 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	83,809,347 - 83,824,759 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	83,501,917 - 83,514,333 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	83,501,918 - 83,517,330 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	83,901,257 - 83,913,673 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	83,410,257 - 83,422,627 (-)	NCBI		MGSCv36	mm8
Celera	17	87,843,482 - 87,856,037 (-)	NCBI		Celera
Cytogenetic Map	17	E4	NCBI
cM Map	17	53.02	NCBI

Cox7a2l
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955441	9,733,894 - 9,743,354 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955441	9,732,168 - 9,743,052 (-)	NCBI	ChiLan1.0	ChiLan1.0

COX7A2L
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	84,046,260 - 84,059,874 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	84,050,233 - 84,063,841 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	42,447,387 - 42,461,792 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	43,299,759 - 43,319,617 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	43,299,759 - 43,319,617 (-)	Ensembl	panpan1.1		panPan2

COX7A2L
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	33,954,882 - 33,976,749 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	33,955,118 - 33,976,699 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	33,724,532 - 33,746,618 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	34,722,422 - 34,744,550 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	34,722,441 - 34,744,511 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	33,847,446 - 33,869,523 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	33,909,770 - 33,931,814 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	34,127,318 - 34,149,512 (-)	NCBI		UU_Cfam_GSD_1.0

Cox7a2l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	37,851,353 - 37,858,670 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936508	9,279,974 - 9,287,279 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

COX7A2L
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	97,951,114 - 97,983,309 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	97,951,115 - 97,983,309 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	104,086,468 - 104,118,648 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

COX7A2L
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	64,895,317 - 64,909,162 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666045	46,995,153 - 47,008,572 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cox7a2l
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624738	23,975,788 - 24,066,011 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624738	24,058,426 - 24,065,764 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Cox7a2l
120 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	103
Count of miRNA genes:	86
Interacting mature miRNAs:	96
Transcripts:	ENSRNOT00000065464
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8552962	Pigfal16	Plasma insulin-like growth factor 1 level QTL 16	9.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	6	1	41223769	Rat
1549905	Stresp10	Stress response QTL 10	6.83	0.0066	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	6	1	27574569	Rat
8693699	Alc37	Alcohol consumption QTL 37	2.6	0.224	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	6	7964167	21301982	Rat
1331743	Uae28	Urinary albumin excretion QTL 28	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	1	34235784	Rat
1300164	Rf15	Renal function QTL 15	3.12		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	5074497	54641141	Rat
9589129	Insul24	Insulin level QTL 24	19.06	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	6	1	41223769	Rat
1578758	Tcas9	Tongue tumor susceptibility QTL 9	3.29		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	6	1	37618905	Rat
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	10894415	110548006	Rat
7411603	Foco13	Food consumption QTL 13	5.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1	41223769	Rat
1598843	Cm63	Cardiac mass QTL 63	2.6		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	1	39036266	Rat
738024	Sach5	Saccharine consumption QTL 5	3.9	0.00039	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	6	1	43394190	Rat
7411542	Bw127	Body weight QTL 127	5.5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	1	41223769	Rat
2293706	Bmd20	Bone mineral density QTL 20	4.3	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	6	5074497	19988050	Rat
9589048	Scfw3	Subcutaneous fat weight QTL 3	4.57	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	6	1	41223769	Rat
2292616	Ept15	Estrogen-induced pituitary tumorigenesis QTL 15	4.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	6	9843312	20338915	Rat
738023	Alc17	Alcohol consumption QTL 17	3.1	0.003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	6	1	27574569	Rat
1354616	Despr12	Despair related QTL 12		0.0012	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	6	1	27574569	Rat
2293709	Bss23	Bone structure and strength QTL 23	5.18	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	6	1	42487980	Rat
2293650	Bss31	Bone structure and strength QTL 31	5.05	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	6	1	42487980	Rat
7411584	Foco4	Food consumption QTL 4	4.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1	42838846	Rat
2300176	Bmd51	Bone mineral density QTL 51	11.7	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	6	1	27574569	Rat
1300128	Rf16	Renal function QTL 16	3.89		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	5074497	34434305	Rat
2301972	Bp325	Blood pressure QTL 325	4.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	1	72227641	Rat
2293656	Bss28	Bone structure and strength QTL 28	6.79	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	6	1	42487980	Rat
1358190	Ept1	Estrogen-induced pituitary tumorigenesis QTL 1	4.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	6	9843312	20338915	Rat
2300190	Bmd52	Bone mineral density QTL 52	11.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	6	1	27574569	Rat
8693690	Alc35	Alcohol consumption QTL 35	2.2	0.606	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	6	7964167	21301982	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106704	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399338	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399340	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399341	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_174177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_174178	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_174179	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_174180	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_174181	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC112092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC166896	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213890	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ215773	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ219925	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220707	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000065464 ⟹ ENSRNOP00000063344

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	11,184,311 - 11,198,273 (+)	Ensembl
Rnor_6.0 Ensembl	6	6,695,827 - 6,709,783 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000095241 ⟹ ENSRNOP00000090089

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	11,184,285 - 11,197,617 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000105892 ⟹ ENSRNOP00000088968

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	11,184,302 - 11,198,272 (+)	Ensembl

RefSeq Acc Id:

NM_001106704 ⟹ NP_001100174

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	16,936,795 - 16,950,797 (+)	NCBI
mRatBN7.2	6	11,184,285 - 11,198,287 (+)	NCBI
Rnor_6.0	6	6,695,821 - 6,709,783 (-)	NCBI
Rnor_5.0	6	6,650,352 - 6,664,329 (-)	NCBI
RGSC_v3.4	6	6,834,523 - 6,861,652 (-)	RGD
Celera	6	10,889,441 - 10,903,386 (+)	RGD

Sequence:

show sequence

GGGTCCTTTTCTAGGGCGGTCGCACAGGCAGCGGCAGTGCGAAGCTGGCTTCAGCCAACATGTA
CTACAAGTTTAGCAGTTTCACGCAGAAGTTGGCTAGTGCTTGGGCTTCGGAAGCCTATACTCCG
CAGGTACGGGTGTGCCGCGTCGCCTTGAGCGAGAGAACGGCGGCCCGAGGCAGGCAGTCGCGAC
GTCCGAGCCGGGAGGGGTTTCTGCCGGCCTATGGGTCCGGCTTACTCGCGTCTCCTGGAATCCT
TTCACGCAGGCTTGGAGCAGTCGCCGAGGTTTCTCTGTGTGTACGGCACCCTAGGCAAGGGTTT
TAAGCCGGTTTCCAGAGAAGCACCGCCTATCATATTTGCCACACCGACCAAACTGACCTCCAGT
GTGACAGCATATGACTATGCTGGGAAGAATAAAGTTCCAGAGCTACAGAGATTCTTCCAGAAGG
CTGACGGTGTGCCCATCCACCTGAAACGAGGCCTTCCGGACCAAATGCTTTACCGGACCACCAT
GGCTCTCACAGTGGGAGGGACCATCTACTGCCTGATCGCCCTCTACATGGCCTCGAAGCCCAAA
AACAAATGAATTTGCCTGTGGAGGACTGGTTTACTTTGTGACACAAACCCTTTGAATTCTCGAG
TTTCATTTTTTCCCCCCTTGGATAGTCTCCTTAACATTTTGCAAACAAAGGAAAAGATAAGAAT
ACACTGGTTTGTTTATGGCGTGCAGATGGCCTGTCAGATGTCAGCTTGTTTTACAGTTAGAACT
ATTGTTTAAGGAAATGACACCAAGCCATCGCTGAGCCATCGTGCTCCTGGTCTCCCACGAGATT
CTGGGTGAAAGTTGTTCACAAACTCACTCATGGCCAGCAGTGCTCAGGGCCTCCGGGACTCGGG
GGGTGTCTGAGTGTGAAGCAGAGAAGCCTTTTGGGTGTAGGTGTGATTGAGGAAGGAGACCAAA
GCCAGGGCACAGGTGGGTGACATGAGGGCTTGAGTTAGCCACCCGGGGGGTTGCTCCACCTTGC
AGAAAAATGCTAGTAGAAATTATTTGCAGTCTGCCTCTAATTGTTGGGCAGTTTGTTTCAAAGG
GTTGTTTGCCTCTCCCAGACCTTAGGGAAGTGTGTCTTTGTTTCATCATGGGAAAGAACACCTG
TCAGTGTTGCACTTTAGACAGCTGTACCAGTAATTCTCCTTTAATCATGCTGCGGCTTGACGTT
ATGATTTACTTGACTGCGGAATAAA

hide sequence

RefSeq Acc Id:

NM_001399338 ⟹ NP_001386267

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	16,936,795 - 16,950,797 (+)	NCBI
mRatBN7.2	6	11,184,285 - 11,198,287 (+)	NCBI

RefSeq Acc Id:

NM_001399340 ⟹ NP_001386269

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	16,936,795 - 16,950,797 (+)	NCBI
mRatBN7.2	6	11,184,285 - 11,198,287 (+)	NCBI

RefSeq Acc Id:

NM_001399341 ⟹ NP_001386270

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	16,936,795 - 16,950,797 (+)	NCBI
mRatBN7.2	6	11,184,285 - 11,198,287 (+)	NCBI

RefSeq Acc Id:

NR_174177

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	16,936,795 - 16,950,797 (+)	NCBI
mRatBN7.2	6	11,184,285 - 11,198,287 (+)	NCBI

RefSeq Acc Id:

NR_174178

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	16,936,574 - 16,950,797 (+)	NCBI
mRatBN7.2	6	11,184,064 - 11,198,287 (+)	NCBI

RefSeq Acc Id:

NR_174179

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	16,936,795 - 16,950,797 (+)	NCBI
mRatBN7.2	6	11,184,285 - 11,198,287 (+)	NCBI

RefSeq Acc Id:

NR_174180

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	16,936,795 - 16,950,797 (+)	NCBI
mRatBN7.2	6	11,184,285 - 11,198,287 (+)	NCBI

RefSeq Acc Id:

NR_174181

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	16,936,795 - 16,950,797 (+)	NCBI
mRatBN7.2	6	11,184,285 - 11,198,287 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100174	(Get FASTA)	NCBI Sequence Viewer
	NP_001386267	(Get FASTA)	NCBI Sequence Viewer
	NP_001386269	(Get FASTA)	NCBI Sequence Viewer
	NP_001386270	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI66896	(Get FASTA)	NCBI Sequence Viewer
	EDM02728	(Get FASTA)	NCBI Sequence Viewer
	EDM02729	(Get FASTA)	NCBI Sequence Viewer
	EDM02730	(Get FASTA)	NCBI Sequence Viewer
	EDM02731	(Get FASTA)	NCBI Sequence Viewer
	EDM02732	(Get FASTA)	NCBI Sequence Viewer
	EDM02733	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000063344
	ENSRNOP00000063344.1
	ENSRNOP00000088968.1
	ENSRNOP00000090089.1

RefSeq Acc Id:	NP_001100174 ⟸ NM_001106704
- Peptide Label:	isoform 1
- UniProtKB:	D3ZYX8 (UniProtKB/TrEMBL), A6H9M6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGPAYSRLLESFHAGLEQSPRFLCVYGTLGKGFKPVSREAPPIIFATPTKLTSSVTAYDYAGKN KVPELQRFFQKADGVPIHLKRGLPDQMLYRTTMALTVGGTIYCLIALYMASKPKNK hide sequence

Ensembl Acc Id:

ENSRNOP00000063344 ⟸ ENSRNOT00000065464

Ensembl Acc Id:

ENSRNOP00000088968 ⟸ ENSRNOT00000105892

Ensembl Acc Id:

ENSRNOP00000090089 ⟸ ENSRNOT00000095241

RefSeq Acc Id:	NP_001386267 ⟸ NM_001399338
- Peptide Label:	isoform 2
- UniProtKB:	A0A8I6GHX2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386269 ⟸ NM_001399340
- Peptide Label:	isoform 3
- UniProtKB:	B2RYT5 (UniProtKB/TrEMBL), A0A8I6AAY1 (UniProtKB/TrEMBL), A0A8I6GHX2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001386270 ⟸ NM_001399341
- Peptide Label:	isoform 4
- UniProtKB:	A0A8I6AAY1 (UniProtKB/TrEMBL), A0A8I6GHX2 (UniProtKB/TrEMBL)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZYX8-F1-model_v2	AlphaFold	D3ZYX8	1-120	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694370

Promoter ID:

EPDNEW_R4895

Type:

multiple initiation site

Name:

Cox7a2l_1

Description:

cytochrome c oxidase subunit 7A2 like

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	6,709,779 - 6,709,839	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306111	AgrOrtholog
BioCyc Gene	G2FUF-38610	BioCyc
BioCyc Pathway	PWY-3781 [aerobic respiration I (cytochrome c)]	BioCyc
	PWY-7279 [aerobic respiration II (cytochrome c) (yeast)]	BioCyc
BioCyc Pathway Image	PWY-3781	BioCyc
	PWY-7279	BioCyc
Ensembl Genes	ENSRNOG00000004526	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000065464	ENTREZGENE
	ENSRNOT00000065464.3	UniProtKB/TrEMBL
	ENSRNOT00000095241.1	UniProtKB/TrEMBL
	ENSRNOT00000105892	ENTREZGENE
	ENSRNOT00000105892.1	UniProtKB/TrEMBL
Gene3D-CATH	4.10.91.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:6921504	IMAGE-MGC_LOAD
InterPro	COX7a	UniProtKB/TrEMBL
	Cyt_c_oxidase_su7a	UniProtKB/TrEMBL
	Cyt_c_oxidase_su7a-rel_mt	UniProtKB/TrEMBL
	Cyt_c_oxidase_su7a_sf	UniProtKB/TrEMBL
KEGG Report	rno:298762	UniProtKB/TrEMBL
MGC_CLONE	MGC:188853	IMAGE-MGC_LOAD
NCBI Gene	298762	ENTREZGENE
PANTHER	COX7a	UniProtKB/TrEMBL
	PTHR10510:SF2	UniProtKB/TrEMBL
Pfam	COX7a	UniProtKB/TrEMBL
PhenoGen	Cox7a2l	PhenoGen
PIRSF	COX7A-rel_mt	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000004526	RatGTEx
Superfamily-SCOP	Cyt_c_oxidase_7a_su	UniProtKB/TrEMBL
UniProt	A0A8I6AAY1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GHX2	ENTREZGENE, UniProtKB/TrEMBL
	A6H9M6	ENTREZGENE, UniProtKB/TrEMBL
	B2RYT5	ENTREZGENE, UniProtKB/TrEMBL
	D3ZYX8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-17	Cox7a2l	cytochrome c oxidase subunit 7A2 like	Cox7a2l	cytochrome c oxidase subunit VIIa polypeptide 2 like	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Cox7a2l	cytochrome c oxidase subunit VIIa polypeptide 2 like	Cox7a2l_predicted	cytochrome c oxidase subunit VIIa polypeptide 2 like (predicted)	'predicted' is removed	2292626	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

BioCyc Pathways

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

BioCyc Pathways