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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-demecolcine | decreases expression | ISO | RGD:1604281 | 6480464 | Demecolcine results in decreased expression of LBH mRNA | CTD | PMID:23649840 | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of LBH mRNA | CTD | PMID:25380136, PMID:30723492 | 17beta-estradiol | affects expression | ISO | RGD:1604281 | 6480464 | Estradiol affects the expression of LBH mRNA | CTD | PMID:22574217 | 17beta-estradiol | multiple interactions | ISO | RGD:1604281 | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of LBH mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1615008 | 6480464 | Tetrachlorodibenzodioxin affects the expression of LBH mRNA | CTD | PMID:26377647 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | RGD:1615008 | 6480464 | tetrabromobisphenol A results in decreased expression of LBH mRNA | CTD | PMID:25172293 | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4, 4'-diaminodiphenylmethane results in increased expression of LBH mRNA | CTD | PMID:25380136 | 4-hydroxyphenyl retinamide | increases expression | ISO | RGD:1615008 | 6480464 | Fenretinide results in increased expression of LBH mRNA | CTD | PMID:28973697 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of LBH mRNA | CTD | PMID:31881176 | all-trans-retinoic acid | increases expression | ISO | RGD:1604281 | 6480464 | Tretinoin results in increased expression of LBH mRNA | CTD | PMID:21934132, PMID:23830798 | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of LBH mRNA | CTD | PMID:30779732 | arsenite(3-) | affects expression | ISO | RGD:1604281 | 6480464 | arsenite affects the expression of LBH mRNA | CTD | PMID:22959463 | benzo[a]pyrene | decreases expression | ISO | RGD:1604281 | 6480464 | Benzoapyrene results in decreased expression of LBH mRNA | CTD | PMID:22178795 | benzo[a]pyrene | increases expression | ISO | RGD:1604281 | 6480464 | Benzoapyrene results in increased expression of LBH mRNA | CTD | PMID:32234424 | benzo[a]pyrene | increases methylation | ISO | RGD:1604281 | 6480464 | Benzoapyrene results in increased methylation of LBH promoter | CTD | PMID:27901495 | bis(2-chloroethyl) sulfide | increases expression | ISO | RGD:1604281 | 6480464 | Mustard Gas results in increased expression of LBH mRNA | CTD | PMID:25102026 | bis(2-ethylhexyl) phthalate | increases expression | ISO | RGD:1604281 | 6480464 | Diethylhexyl Phthalate results in increased expression of LBH mRNA | CTD | PMID:31163220 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of LBH mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of LBH mRNA | CTD | PMID:30816183 | bisphenol A | decreases expression | ISO | RGD:1604281 | 6480464 | bisphenol A results in decreased expression of LBH mRNA | CTD | PMID:27685785 | butan-1-ol | multiple interactions | ISO | RGD:1604281 | 6480464 | [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of LBH mRNA | CTD | PMID:29432896 | butanal | increases expression | ISO | RGD:1604281 | 6480464 | butyraldehyde results in increased expression of LBH mRNA | CTD | PMID:26079696 | calcitriol | increases expression | ISO | RGD:1604281 | 6480464 | Calcitriol results in increased expression of LBH mRNA | CTD | PMID:16002434 | carbon nanotube | affects expression | ISO | RGD:1615008 | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chloroprene | decreases expression | ISO | RGD:1615008 | 6480464 | Chloroprene results in decreased expression of LBH mRNA | CTD | PMID:23125180 | choline | multiple interactions | ISO | RGD:1615008 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of LBH mRNA | CTD | PMID:20938992 | cisplatin | multiple interactions | ISO | RGD:1604281 | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of LBH mRNA | CTD | PMID:27392435 | clobetasol | increases expression | ISO | RGD:1615008 | 6480464 | Clobetasol results in increased expression of LBH mRNA | CTD | PMID:27462272 | copper atom | increases expression | EXP | | 6480464 | Copper results in increased expression of LBH mRNA | CTD | PMID:30556269 | copper(0) | increases expression | EXP | | 6480464 | Copper results in increased expression of LBH mRNA | CTD | PMID:30556269 | copper(II) sulfate | increases expression | ISO | RGD:1604281 | 6480464 | Copper Sulfate results in increased expression of LBH mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | RGD:1604281 | 6480464 | Cyclosporine results in decreased expression of LBH mRNA | CTD | PMID:20106945, PMID:27989131 | cytarabine | decreases expression | ISO | RGD:1604281 | 6480464 | Cytarabine results in decreased expression of LBH mRNA | CTD | PMID:21198554 | DDT | increases expression | ISO | RGD:1615008 | 6480464 | DDT results in increased expression of LBH mRNA | CTD | PMID:24814263 | dibutyl phthalate | increases expression | ISO | RGD:1615008 | 6480464 | Dibutyl Phthalate results in increased expression of LBH mRNA | CTD | PMID:21266533 | dioxygen | multiple interactions | ISO | RGD:1615008 | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of LBH mRNA | CTD | PMID:30529165 | doxorubicin | decreases expression | ISO | RGD:1604281 | 6480464 | Doxorubicin results in decreased expression of LBH mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of LBH mRNA | CTD | PMID:29391264 | ethanol | multiple interactions | ISO | RGD:1604281 | 6480464 | [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of LBH mRNA | CTD | PMID:29432896 | fenofibrate | increases expression | ISO | RGD:1604281 | 6480464 | Fenofibrate results in increased expression of LBH mRNA | CTD | PMID:25572481 | folic acid | multiple interactions | ISO | RGD:1615008 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of LBH mRNA | CTD | PMID:20938992 | genistein | increases expression | ISO | RGD:1615008 | 6480464 | Genistein results in increased expression of LBH mRNA | CTD | PMID:32186404 | hydrogen peroxide | affects expression | ISO | RGD:1604281 | 6480464 | Hydrogen Peroxide affects the expression of LBH mRNA | CTD | PMID:20044591 | indometacin | increases expression | ISO | RGD:1604281 | 6480464 | Indomethacin results in increased expression of LBH mRNA | CTD | PMID:16984733 | irinotecan | decreases expression | ISO | RGD:1604281 | 6480464 | Irinotecan analog results in decreased expression of LBH mRNA | CTD | PMID:18927307 | isobutanol | multiple interactions | ISO | RGD:1604281 | 6480464 | [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of LBH mRNA | CTD | PMID:29432896 | isoprenaline | decreases expression | ISO | RGD:1615008 | 6480464 | Isoproterenol results in decreased expression of LBH mRNA | CTD | PMID:20003209 | L-methionine | multiple interactions | ISO | RGD:1615008 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of LBH mRNA | CTD | PMID:20938992 | lead diacetate | decreases expression | ISO | RGD:1615008 | 6480464 | lead acetate results in decreased expression of LBH mRNA | CTD | PMID:21829687 | lipopolysaccharide | decreases expression | ISO | RGD:1615008 | 6480464 | Lipopolysaccharides results in decreased expression of LBH mRNA | CTD | PMID:25890327 | methylisothiazolinone | increases expression | ISO | RGD:1604281 | 6480464 | 2-methyl-4-isothiazolin-3-one results in increased expression of LBH mRNA | CTD | PMID:31629900 | methylmercury chloride | increases expression | ISO | RGD:1604281 | 6480464 | methylmercuric chloride results in increased expression of LBH mRNA | CTD | PMID:28001369 | mitoxantrone | affects response to substance | ISO | RGD:1604281 | 6480464 | LBH protein affects the susceptibility to Mitoxantrone | CTD | PMID:16217747 | mono(2-ethylhexyl) phthalate | affects expression | ISO | RGD:1615008 | 6480464 | mono-2-ethylhexylphthalate affects the expression of LBH mRNA | CTD | PMID:21195148 | Monobutylphthalate | affects expression | ISO | RGD:1615008 | 6480464 | monobutyl phthalate affects the expression of LBH mRNA | CTD | PMID:21195148 | N-methyl-4-phenylpyridinium | decreases expression | ISO | RGD:1604281 | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of LBH mRNA | CTD | PMID:24810058 | N-nitrosodimethylamine | increases expression | EXP | | 6480464 | Dimethylnitrosamine results in increased expression of LBH mRNA | CTD | PMID:25380136 | naphthalene | increases expression | ISO | RGD:1615008 | 6480464 | naphthalene results in increased expression of LBH mRNA | CTD | PMID:18978301 | p-toluidine | decreases expression | EXP | | 6480464 | 4-toluidine results in decreased expression of LBH mRNA | CTD | PMID:27638505 | pentanal | increases expression | ISO | RGD:1604281 | 6480464 | pentanal results in increased expression of LBH mRNA | CTD | PMID:26079696 | pirinixic acid | increases expression | ISO | RGD:1615008 | 6480464 | pirinixic acid results in increased expression of LBH mRNA | CTD | PMID:18301758 | propanal | increases expression | ISO | RGD:1604281 | 6480464 | propionaldehyde results in increased expression of LBH mRNA | CTD | PMID:26079696 | quercetin | increases expression | ISO | RGD:1604281 | 6480464 | Quercetin results in increased expression of LBH mRNA | CTD | PMID:21632981 | raloxifene | multiple interactions | ISO | RGD:1604281 | 6480464 | [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LBH mRNA | CTD | PMID:19059307 | silicon dioxide | decreases expression | ISO | RGD:1604281 | 6480464 | Silicon Dioxide analog results in decreased expression of LBH mRNA | CTD | PMID:25895662 | silicon dioxide | increases expression | ISO | RGD:1604281 | 6480464 | Silicon Dioxide results in increased expression of LBH mRNA | CTD | PMID:25351596 | silver atom | increases expression | ISO | RGD:1604281 | 6480464 | Silver results in increased expression of LBH mRNA | CTD | PMID:28959546 | silver(0) | increases expression | ISO | RGD:1604281 | 6480464 | Silver results in increased expression of LBH mRNA | CTD | PMID:28959546 | simvastatin | increases expression | ISO | RGD:1615008 | 6480464 | Simvastatin results in increased expression of LBH mRNA | CTD | PMID:19262002 | sodium arsenate | decreases expression | ISO | RGD:1615008 | 6480464 | sodium arsenate results in decreased expression of LBH mRNA | CTD | PMID:21795629 | sodium arsenite | increases expression | ISO | RGD:1615008 | 6480464 | sodium arsenite results in increased expression of LBH mRNA | CTD | PMID:16322246 | sodium arsenite | increases expression | ISO | RGD:1604281 | 6480464 | sodium arsenite results in increased expression of LBH mRNA | CTD | PMID:29301061 | sunitinib | increases expression | ISO | RGD:1604281 | 6480464 | Sunitinib results in increased expression of LBH mRNA | CTD | PMID:31533062 | tamoxifen | multiple interactions | ISO | RGD:1604281 | 6480464 | [Tamoxifen co-treated with ESR2 protein] results in decreased expression of LBH mRNA | CTD | PMID:19059307 | tebuconazole | decreases expression | ISO | RGD:1604281 | 6480464 | tebuconazole results in decreased expression of LBH mRNA | CTD | PMID:30458266 | tetrachloromethane | affects expression | ISO | RGD:1615008 | 6480464 | Carbon Tetrachloride affects the expression of LBH mRNA | CTD | PMID:17484886 | thapsigargin | increases expression | ISO | RGD:1604281 | 6480464 | Thapsigargin results in increased expression of LBH mRNA | CTD | PMID:29453283 | titanium dioxide | decreases expression | ISO | RGD:1615008 | 6480464 | titanium dioxide results in decreased expression of LBH mRNA | CTD | PMID:23409001 | trichostatin A | increases expression | ISO | RGD:1604281 | 6480464 | trichostatin A results in increased expression of LBH mRNA | CTD | PMID:24935251 | triclosan | decreases expression | ISO | RGD:1604281 | 6480464 | Triclosan results in decreased expression of LBH mRNA | CTD | PMID:30510588 | urethane | increases expression | ISO | RGD:1604281 | 6480464 | Urethane results in increased expression of LBH mRNA | CTD | PMID:28818685 | valdecoxib | decreases expression | EXP | | 6480464 | valdecoxib results in decreased expression of LBH mRNA | CTD | PMID:24136188 | valproic acid | increases expression | ISO | RGD:1615008 | 6480464 | Valproic Acid results in increased expression of LBH mRNA | CTD | PMID:21427059 | valproic acid | increases expression | ISO | RGD:1604281 | 6480464 | Valproic Acid results in increased expression of LBH mRNA | CTD | PMID:24935251, PMID:28001369 | valproic acid | decreases expression | ISO | RGD:1604281 | 6480464 | Valproic Acid results in decreased expression of LBH mRNA | CTD | PMID:29154799 | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of LBH mRNA | CTD | PMID:23034163 | vincristine | decreases expression | ISO | RGD:1604281 | 6480464 | Vincristine results in decreased expression of LBH mRNA | CTD | PMID:23649840 | zoledronic acid | increases expression | ISO | RGD:1604281 | 6480464 | zoledronic acid results in increased expression of LBH mRNA | CTD | PMID:24714768 | |