Epas1 Rat (1->4)-beta-D-glucan multiple interactions ISO Epas1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of EPAS1 mRNA CTD PMID:36331819 Epas1 Rat 1,2-dimethylhydrazine decreases expression ISO Epas1 (Mus musculus) 6480464 1,2-Dimethylhydrazine results in decreased expression of EPAS1 mRNA CTD PMID:22206623 Epas1 Rat 1,2-dimethylhydrazine multiple interactions ISO Epas1 (Mus musculus) 6480464 Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of EPAS1 mRNA] CTD PMID:22206623 Epas1 Rat 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO Epas1 (Mus musculus) 6480464 [3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of EPAS1 mRNA CTD PMID:19679656 Epas1 Rat 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of EPAS1 mRNA CTD PMID:17351261 Epas1 Rat 17beta-estradiol multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of EPAS1 mRNA; EGF protein inhibits more ... CTD PMID:24758408|PMID:30165855 Epas1 Rat 17beta-estradiol decreases expression ISO Epas1 (Mus musculus) 6480464 Estradiol results in decreased expression of EPAS1 mRNA CTD PMID:39298647 Epas1 Rat 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of EPAS1 mRNA CTD PMID:32145629 Epas1 Rat 17beta-estradiol multiple interactions ISO Epas1 (Mus musculus) 6480464 [letrozole results in decreased abundance of Estradiol] which results in decreased expression of EPAS1 mRNA CTD PMID:19620711 Epas1 Rat 17beta-estradiol decreases expression ISO EPAS1 (Homo sapiens) 6480464 Estradiol results in decreased expression of EPAS1 mRNA CTD PMID:24758408|PMID:28591870|PMID:28711546 Epas1 Rat 1H-benzimidazole increases stability EXP 6480464 benzimidazole results in increased stability of EPAS1 protein CTD PMID:23545307 Epas1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Epas1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of EPAS1 mRNA CTD PMID:16962184|PMID:24058054|PMID:24680724 Epas1 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Epas1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to EPAS1 gene] CTD PMID:28213091 Epas1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of EPAS1 mRNA CTD PMID:22298810|PMID:34747641 Epas1 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Epas1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of EPAS1 mRNA CTD PMID:19933214|PMID:28213091|PMID:37172768 Epas1 Rat 2-amino-2-deoxy-D-glucopyranose decreases expression EXP 6480464 Glucosamine results in decreased expression of EPAS1 mRNA CTD PMID:17109745 Epas1 Rat 2-amino-2-deoxy-D-glucopyranose multiple interactions EXP 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; IL1B affects the more ... CTD PMID:17109745 Epas1 Rat 2-methylcholine affects expression ISO EPAS1 (Homo sapiens) 6480464 beta-methylcholine affects the expression of EPAS1 mRNA CTD PMID:21179406 Epas1 Rat 2-palmitoylglycerol increases expression ISO EPAS1 (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of EPAS1 mRNA CTD PMID:37199045 Epas1 Rat 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of EPAS1 mRNA CTD PMID:23196670 Epas1 Rat 3,3',5-triiodo-L-thyronine increases expression ISO Epas1 (Mus musculus) 6480464 Triiodothyronine results in increased expression of EPAS1 mRNA CTD PMID:25172293 Epas1 Rat 3,4-dihydroxybenzoate increases expression ISO Epas1 (Mus musculus) 6480464 3,4-dihydroxybenzoate results in increased expression of EPAS1 mRNA CTD PMID:19679656 Epas1 Rat 3,4-dihydroxybenzoate multiple interactions ISO Epas1 (Mus musculus) 6480464 [3,4-dihydroxybenzoate co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of EPAS1 mRNA CTD PMID:19679656 Epas1 Rat 3-methylcholanthrene multiple interactions ISO Epas1 (Mus musculus) 6480464 [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of EPAS1 mRNA CTD PMID:23519560 Epas1 Rat 3-phenylprop-2-enal increases expression ISO EPAS1 (Homo sapiens) 6480464 cinnamaldehyde results in increased expression of EPAS1 mRNA CTD PMID:19524605 Epas1 Rat 4,4'-diaminodiphenylmethane increases expression ISO Epas1 (Mus musculus) 6480464 4,4'-diaminodiphenylmethane results in increased expression of EPAS1 mRNA CTD PMID:18648102 Epas1 Rat 4,4'-sulfonyldiphenol multiple interactions ISO Epas1 (Mus musculus) 6480464 [bisphenol S co-treated with Tretinoin] results in decreased expression of EPAS1 mRNA CTD PMID:30951980 Epas1 Rat 4,4'-sulfonyldiphenol decreases expression ISO Epas1 (Mus musculus) 6480464 bisphenol S results in decreased expression of EPAS1 mRNA CTD PMID:39298647 Epas1 Rat 4,4'-sulfonyldiphenol increases expression ISO Epas1 (Mus musculus) 6480464 bisphenol S results in increased expression of EPAS1 mRNA CTD PMID:30951980 Epas1 Rat 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2,6-dinitrotoluene affects the expression of EPAS1 mRNA CTD PMID:21346803 Epas1 Rat 4-hydroperoxycyclophosphamide increases expression ISO Epas1 (Mus musculus) 6480464 perfosfamide results in increased expression of EPAS1 protein CTD PMID:23251655 Epas1 Rat 4-hydroxy-TEMPO affects localization ISO EPAS1 (Homo sapiens) 6480464 tempol affects the localization of EPAS1 protein CTD PMID:24755467 Epas1 Rat 5-fluorouracil increases expression ISO EPAS1 (Homo sapiens) 6480464 Fluorouracil results in increased expression of EPAS1 mRNA CTD PMID:16557594 Epas1 Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of EPAS1 mRNA CTD PMID:24780913 Epas1 Rat acetaldehyde multiple interactions ISO EPAS1 (Homo sapiens) 6480464 oxalylglycine inhibits the reaction [Acetaldehyde results in decreased expression of EPAS1 protein]; VH298 inhibits the more ... CTD PMID:35504338 Epas1 Rat acetaldehyde decreases expression ISO EPAS1 (Homo sapiens) 6480464 Acetaldehyde results in decreased expression of EPAS1 protein CTD PMID:35504338 Epas1 Rat acetamide decreases expression EXP 6480464 acetamide results in decreased expression of EPAS1 mRNA CTD PMID:31881176 Epas1 Rat actinomycin D increases stability EXP 6480464 Dactinomycin results in increased stability of EPAS1 protein CTD PMID:23545307 Epas1 Rat aflatoxin B1 increases methylation ISO EPAS1 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of EPAS1 gene; Aflatoxin B1 results in increased methylation more ... CTD PMID:27153756|PMID:30157460 Epas1 Rat Aflatoxin B2 alpha increases methylation ISO EPAS1 (Homo sapiens) 6480464 aflatoxin B2 results in increased methylation of EPAS1 intron CTD PMID:30157460 Epas1 Rat aldehydo-D-glucosamine decreases expression EXP 6480464 Glucosamine results in decreased expression of EPAS1 mRNA CTD PMID:17109745 Epas1 Rat aldehydo-D-glucosamine multiple interactions EXP 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; IL1B affects the more ... CTD PMID:17109745 Epas1 Rat all-trans-retinoic acid increases expression ISO EPAS1 (Homo sapiens) 6480464 Tretinoin results in increased expression of EPAS1 mRNA CTD PMID:15894607|PMID:17138961|PMID:21934132 Epas1 Rat all-trans-retinoic acid multiple interactions ISO Epas1 (Mus musculus) 6480464 [bisphenol S co-treated with Tretinoin] results in decreased expression of EPAS1 mRNA CTD PMID:30951980 Epas1 Rat alpha-Zearalanol multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of EPAS1 mRNA CTD PMID:35163327 Epas1 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of EPAS1 mRNA CTD PMID:16483693 Epas1 Rat ammonium chloride multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Formaldehyde inhibits the reaction [Ammonium Chloride results in increased expression of EPAS1 protein] CTD PMID:35504338 Epas1 Rat ammonium chloride increases expression ISO EPAS1 (Homo sapiens) 6480464 Ammonium Chloride results in increased expression of EPAS1 protein CTD PMID:35504338 Epas1 Rat antimycin A multiple interactions EXP 6480464 Antimycin A inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:18353899 Epas1 Rat aristolochic acid A increases expression ISO EPAS1 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of EPAS1 protein CTD PMID:21554934 Epas1 Rat aristolochic acid A decreases expression ISO EPAS1 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of EPAS1 mRNA CTD PMID:33212167 Epas1 Rat arsenite(3-) multiple interactions ISO EPAS1 (Homo sapiens) 6480464 arsenite inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of EPAS1 protein]; arsenite results more ... CTD PMID:22447124 Epas1 Rat arsenite(3-) increases expression ISO EPAS1 (Homo sapiens) 6480464 arsenite results in increased expression of EPAS1 protein CTD PMID:22447124 Epas1 Rat atrazine decreases expression ISO EPAS1 (Homo sapiens) 6480464 Atrazine results in decreased expression of EPAS1 mRNA CTD PMID:22378314 Epas1 Rat benzo[a]pyrene decreases expression ISO Epas1 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of EPAS1 mRNA CTD PMID:19770486|PMID:22228805 Epas1 Rat benzo[a]pyrene multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Air Pollutants results in increased abundance of [Benzo(a)pyrene co-treated with ceric oxide]] which results in more ... CTD PMID:36982514 Epas1 Rat benzo[a]pyrene increases methylation ISO Epas1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased methylation of EPAS1 intron CTD PMID:27901495 Epas1 Rat benzo[a]pyrene decreases expression ISO EPAS1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of EPAS1 mRNA CTD PMID:30453624 Epas1 Rat benzo[a]pyrene increases expression ISO Epas1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of EPAS1 mRNA CTD PMID:22228805|PMID:23735875 Epas1 Rat benzo[a]pyrene affects response to substance ISO EPAS1 (Homo sapiens) 6480464 EPAS1 protein affects the susceptibility to Benzo(a)pyrene CTD PMID:23333640 Epas1 Rat benzo[a]pyrene diol epoxide I increases expression ISO EPAS1 (Homo sapiens) 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of EPAS1 mRNA CTD PMID:20382639 Epas1 Rat benzo[a]pyrene diol epoxide I increases expression ISO Epas1 (Mus musculus) 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of EPAS1 mRNA CTD PMID:39826883 Epas1 Rat benzo[a]pyrene diol epoxide I decreases expression ISO EPAS1 (Homo sapiens) 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of EPAS1 mRNA CTD PMID:19150397 Epas1 Rat beta-D-glucosamine decreases expression EXP 6480464 Glucosamine results in decreased expression of EPAS1 mRNA CTD PMID:17109745 Epas1 Rat beta-D-glucosamine multiple interactions EXP 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; IL1B affects the more ... CTD PMID:17109745 Epas1 Rat bis(2-chloroethyl) sulfide increases expression ISO Epas1 (Mus musculus) 6480464 Mustard Gas results in increased expression of EPAS1 mRNA CTD PMID:15674843 Epas1 Rat bis(2-ethylhexyl) phthalate increases expression ISO EPAS1 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of EPAS1 mRNA CTD PMID:31163220 Epas1 Rat bis(2-ethylhexyl) phthalate decreases expression ISO Epas1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of EPAS1 mRNA CTD PMID:34319233 Epas1 Rat bisphenol A decreases expression ISO EPAS1 (Homo sapiens) 6480464 bisphenol A results in decreased expression of EPAS1 mRNA CTD PMID:28711546 Epas1 Rat bisphenol A multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of EPAS1 gene CTD PMID:31601247 Epas1 Rat bisphenol A decreases methylation ISO EPAS1 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of EPAS1 gene CTD PMID:31601247 Epas1 Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of EPAS1 mRNA CTD PMID:32145629 Epas1 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of EPAS1 mRNA CTD PMID:30816183 Epas1 Rat bisphenol A affects expression ISO EPAS1 (Homo sapiens) 6480464 bisphenol A affects the expression of EPAS1 mRNA CTD PMID:30903817 Epas1 Rat bisphenol A increases expression ISO EPAS1 (Homo sapiens) 6480464 bisphenol A results in increased expression of EPAS1 mRNA CTD PMID:29275510 Epas1 Rat bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of EPAS1 gene CTD PMID:28505145 Epas1 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of EPAS1 mRNA CTD PMID:25181051 Epas1 Rat bisphenol AF decreases expression ISO EPAS1 (Homo sapiens) 6480464 bisphenol AF results in decreased expression of EPAS1 mRNA CTD PMID:28591870 Epas1 Rat Bisphenol B decreases expression ISO EPAS1 (Homo sapiens) 6480464 bisphenol B results in decreased expression of EPAS1 mRNA CTD PMID:28591870 Epas1 Rat bisphenol F decreases expression ISO EPAS1 (Homo sapiens) 6480464 bisphenol F results in decreased expression of EPAS1 mRNA CTD PMID:28591870 Epas1 Rat bisphenol F increases expression ISO Epas1 (Mus musculus) 6480464 bisphenol F results in increased expression of EPAS1 mRNA CTD PMID:38685157 Epas1 Rat Bisphenol Z decreases expression ISO EPAS1 (Homo sapiens) 6480464 bisphenol Z results in decreased expression of EPAS1 mRNA CTD PMID:28591870 Epas1 Rat butan-1-ol multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic more ... CTD PMID:29432896 Epas1 Rat cadmium atom multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which affects the folding of EPAS1 protein; more ... CTD PMID:35504338 Epas1 Rat cadmium atom multiple interactions ISO Epas1 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EPAS1 more ... CTD PMID:37325564 Epas1 Rat cadmium dichloride increases methylation EXP 6480464 Cadmium Chloride results in increased methylation of EPAS1 promoter CTD PMID:22457795 Epas1 Rat cadmium dichloride multiple interactions ISO Epas1 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EPAS1 more ... CTD PMID:37325564 Epas1 Rat cadmium dichloride multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which affects the folding of EPAS1 protein; more ... CTD PMID:35504338 Epas1 Rat cadmium dichloride decreases expression ISO EPAS1 (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of EPAS1 mRNA CTD PMID:38568856 Epas1 Rat cannabidiol decreases methylation ISO Epas1 (Mus musculus) 6480464 Cannabidiol results in decreased methylation of EPAS1 gene CTD PMID:33407853 Epas1 Rat carbon nanotube decreases expression ISO Epas1 (Mus musculus) 6480464 Nanotubes, Carbon analog results in decreased expression of EPAS1 mRNA; Nanotubes, Carbon results in decreased more ... CTD PMID:25554681 Epas1 Rat ceric oxide multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Air Pollutants results in increased abundance of [Benzo(a)pyrene co-treated with ceric oxide]] which results in more ... CTD PMID:36982514 Epas1 Rat chloropicrin affects expression ISO EPAS1 (Homo sapiens) 6480464 chloropicrin affects the expression of EPAS1 mRNA CTD PMID:26352163 Epas1 Rat chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of EPAS1 mRNA CTD PMID:18668222 Epas1 Rat choline multiple interactions ISO Epas1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression more ... CTD PMID:20938992 Epas1 Rat chromium(6+) affects expression ISO Epas1 (Mus musculus) 6480464 chromium hexavalent ion affects the expression of EPAS1 mRNA CTD PMID:28472532 Epas1 Rat ciglitazone multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [ciglitazone binds to PPARG protein] which results in increased expression of EPAS1 mRNA CTD PMID:16197558 Epas1 Rat clofibrate decreases expression ISO Epas1 (Mus musculus) 6480464 Clofibrate results in decreased expression of EPAS1 mRNA CTD PMID:23811191 Epas1 Rat cobalt atom multiple interactions ISO Epas1 (Mus musculus) 6480464 EPAS1 protein affects the reaction [Cobalt results in increased abundance of Nitric Oxide] CTD PMID:23788631 Epas1 Rat cobalt atom increases expression EXP 6480464 Cobalt results in increased expression of EPAS1 protein CTD PMID:17967803 Epas1 Rat cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of EPAS1 protein CTD PMID:21558026|PMID:23545307 Epas1 Rat cobalt dichloride increases expression ISO Epas1 (Mus musculus) 6480464 cobaltous chloride results in increased expression of EPAS1 protein CTD PMID:24503013 Epas1 Rat cobalt dichloride increases stability ISO EPAS1 (Homo sapiens) 6480464 cobaltous chloride results in increased stability of EPAS1 protein CTD PMID:18515279 Epas1 Rat cobalt dichloride increases expression ISO EPAS1 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of EPAS1 protein CTD PMID:21036805|PMID:24503013|PMID:24790010|PMID:25805230 Epas1 Rat cobalt dichloride affects localization ISO EPAS1 (Homo sapiens) 6480464 cobaltous chloride affects the localization of EPAS1 protein CTD PMID:21863063 Epas1 Rat cobalt dichloride increases response to substance ISO EPAS1 (Homo sapiens) 6480464 EPAS1 protein results in increased susceptibility to cobaltous chloride CTD PMID:25805230 Epas1 Rat cobalt dichloride multiple interactions EXP 6480464 [AQP1 protein results in increased stability of EPAS1 protein] promotes the reaction [cobaltous chloride results more ... CTD PMID:23545307 Epas1 Rat cobalt dichloride multiple interactions ISO EPAS1 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits more ... CTD PMID:21863063|PMID:23958427|PMID:24790010|PMID:25805230 Epas1 Rat copper atom multiple interactions ISO Epas1 (Mus musculus) 6480464 EPAS1 gene mutant form inhibits the reaction [Copper deficiency results in increased expression of CYBRD1 more ... CTD PMID:23555700 Epas1 Rat copper atom multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of EPAS1 mRNA CTD PMID:30911355 Epas1 Rat copper atom increases expression EXP 6480464 Copper results in increased expression of EPAS1 mRNA CTD PMID:30556269 Epas1 Rat copper atom increases expression ISO Epas1 (Mus musculus) 6480464 Copper deficiency results in increased expression of EPAS1 protein CTD PMID:23555700 Epas1 Rat copper(0) multiple interactions ISO Epas1 (Mus musculus) 6480464 EPAS1 gene mutant form inhibits the reaction [Copper deficiency results in increased expression of CYBRD1 more ... CTD PMID:23555700 Epas1 Rat copper(0) multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of EPAS1 mRNA CTD PMID:30911355 Epas1 Rat copper(0) increases expression EXP 6480464 Copper results in increased expression of EPAS1 mRNA CTD PMID:30556269 Epas1 Rat copper(0) increases expression ISO Epas1 (Mus musculus) 6480464 Copper deficiency results in increased expression of EPAS1 protein CTD PMID:23555700 Epas1 Rat copper(II) sulfate increases expression ISO EPAS1 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of EPAS1 mRNA CTD PMID:19549813 Epas1 Rat crocidolite asbestos increases expression ISO EPAS1 (Homo sapiens) 6480464 Asbestos, Crocidolite results in increased expression of EPAS1 mRNA CTD PMID:18687144 Epas1 Rat curcumin multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Curcumin analog inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:20554536 Epas1 Rat cycloheximide multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Cycloheximide inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein]; Cycloheximide inhibits more ... CTD PMID:23958427|PMID:26735578 Epas1 Rat cycloheximide decreases expression ISO EPAS1 (Homo sapiens) 6480464 Cycloheximide results in decreased expression of EPAS1 protein CTD PMID:26735578 Epas1 Rat cyclosporin A decreases expression ISO EPAS1 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of EPAS1 mRNA CTD PMID:20106945|PMID:27989131 Epas1 Rat cyclosporin A increases expression ISO EPAS1 (Homo sapiens) 6480464 Cyclosporine results in increased expression of EPAS1 mRNA CTD PMID:25562108 Epas1 Rat cyclosporin A decreases expression ISO Epas1 (Mus musculus) 6480464 Cyclosporine results in decreased expression of EPAS1 mRNA CTD PMID:19770486 Epas1 Rat DDT decreases expression EXP 6480464 DDT results in decreased expression of EPAS1 mRNA CTD PMID:30207508 Epas1 Rat deguelin decreases expression ISO EPAS1 (Homo sapiens) 6480464 deguelin results in decreased expression of EPAS1 protein CTD PMID:19336726 Epas1 Rat delphinidin multiple interactions ISO EPAS1 (Homo sapiens) 6480464 delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of EPAS1 protein] CTD PMID:18603805 Epas1 Rat desferrioxamine B multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Deferoxamine inhibits the reaction [EPAS1 protein results in increased degradation of COX4I1 protein] CTD PMID:18515279 Epas1 Rat desferrioxamine B increases expression EXP 6480464 Deferoxamine results in increased expression of EPAS1 protein CTD PMID:18353899|PMID:21558026 Epas1 Rat desferrioxamine B increases expression ISO EPAS1 (Homo sapiens) 6480464 Deferoxamine results in increased expression of EPAS1 protein CTD PMID:22447124|PMID:26735578|PMID:27287256 Epas1 Rat desferrioxamine B increases stability ISO EPAS1 (Homo sapiens) 6480464 Deferoxamine results in increased stability of EPAS1 protein CTD PMID:18515279 Epas1 Rat diazinon increases methylation ISO EPAS1 (Homo sapiens) 6480464 Diazinon results in increased methylation of EPAS1 gene CTD PMID:22964155 Epas1 Rat Dibutyl phosphate affects expression ISO EPAS1 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of EPAS1 mRNA CTD PMID:37042841 Epas1 Rat diclofenac decreases expression ISO EPAS1 (Homo sapiens) 6480464 Diclofenac results in decreased expression of EPAS1 protein CTD PMID:12912967 Epas1 Rat dicrotophos increases expression ISO EPAS1 (Homo sapiens) 6480464 dicrotophos results in increased expression of EPAS1 mRNA CTD PMID:28302478 Epas1 Rat diethyl malate affects expression ISO Epas1 (Mus musculus) 6480464 diethyl malate affects the expression of EPAS1 mRNA CTD PMID:24814887 Epas1 Rat diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of EPAS1 mRNA CTD PMID:37077353 Epas1 Rat diisononyl phthalate decreases expression ISO Epas1 (Mus musculus) 6480464 diisononyl phthalate results in decreased expression of EPAS1 mRNA CTD PMID:37482143 Epas1 Rat dinophysistoxin 1 increases expression ISO EPAS1 (Homo sapiens) 6480464 dinophysistoxin 1 results in increased expression of EPAS1 mRNA CTD PMID:28939011 Epas1 Rat dioxygen multiple interactions ISO EPAS1 (Homo sapiens) 6480464 1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl)methyl)pyridin-2-yl)piperazine inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein]; 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits more ... CTD PMID:20046830|PMID:20554536|PMID:21994956|PMID:23406266|PMID:23958427|PMID:24236059|PMID:24403227|PMID:24503013|PMID:25451921|PMID:27292261|PMID:36318118 Epas1 Rat dioxygen increases expression ISO Epas1 (Mus musculus) 6480464 Oxygen deficiency results in increased expression of EPAS1 protein CTD PMID:24503013|PMID:26723917 Epas1 Rat dioxygen affects localization ISO EPAS1 (Homo sapiens) 6480464 Oxygen deficiency affects the localization of EPAS1 protein CTD PMID:24755467 Epas1 Rat dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of EPAS1 protein CTD PMID:18353899|PMID:23545307 Epas1 Rat dioxygen increases expression ISO EPAS1 (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of EPAS1 mRNA; Oxygen deficiency results in increased expression more ... CTD PMID:20554536|PMID:20862257|PMID:21994956|PMID:23406266|PMID:23725749|PMID:24403227|PMID:24503013|PMID:36318118 Epas1 Rat dioxygen multiple interactions ISO Epas1 (Mus musculus) 6480464 Oxygen deficiency affects the localization of and results in increased activity of EPAS1 protein CTD PMID:20880076 Epas1 Rat dioxygen affects response to substance EXP 6480464 EPAS1 protein affects the susceptibility to Oxygen deficiency CTD PMID:12679337 Epas1 Rat dioxygen multiple interactions EXP 6480464 [AQP1 protein results in increased stability of EPAS1 protein] promotes the reaction [Oxygen deficiency results more ... CTD PMID:12679337|PMID:18353899|PMID:23545307|PMID:26095976 Epas1 Rat disodium selenite increases expression ISO EPAS1 (Homo sapiens) 6480464 Sodium Selenite results in increased expression of EPAS1 mRNA CTD PMID:24383545 Epas1 Rat dorsomorphin multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Epas1 Rat doxorubicin decreases expression ISO Epas1 (Mus musculus) 6480464 Doxorubicin results in decreased expression of EPAS1 mRNA CTD PMID:26873546 Epas1 Rat doxorubicin decreases expression ISO EPAS1 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of EPAS1 mRNA CTD PMID:29803840 Epas1 Rat epoxiconazole decreases expression ISO Epas1 (Mus musculus) 6480464 epoxiconazole results in decreased expression of EPAS1 mRNA CTD PMID:35436446 Epas1 Rat ethanol multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic more ... CTD PMID:29432896 Epas1 Rat ethanol increases expression ISO Epas1 (Mus musculus) 6480464 Ethanol results in increased expression of EPAS1 mRNA CTD PMID:30319688 Epas1 Rat ethanol affects splicing ISO Epas1 (Mus musculus) 6480464 Ethanol affects the splicing of EPAS1 mRNA CTD PMID:30319688 Epas1 Rat fenamidone increases expression ISO Epas1 (Mus musculus) 6480464 fenamidone results in increased expression of EPAS1 mRNA CTD PMID:27029645 Epas1 Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of EPAS1 mRNA CTD PMID:24136188 Epas1 Rat folic acid multiple interactions ISO Epas1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression more ... CTD PMID:20938992|PMID:22206623 Epas1 Rat formaldehyde decreases expression ISO EPAS1 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of EPAS1 protein CTD PMID:35504338 Epas1 Rat formaldehyde multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Formaldehyde co-treated with pevonedistat co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the folding of EPAS1 protein; [Formaldehyde more ... CTD PMID:35504338 Epas1 Rat fulvestrant multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of EPAS1 gene CTD PMID:31601247 Epas1 Rat furan increases expression ISO Epas1 (Mus musculus) 6480464 furan results in increased expression of EPAS1 mRNA CTD PMID:24183702 Epas1 Rat galangin multiple interactions ISO EPAS1 (Homo sapiens) 6480464 ferrous sulfate inhibits the reaction [galangin results in increased expression of EPAS1 protein]; Iron inhibits more ... CTD PMID:17973296 Epas1 Rat galangin increases expression ISO EPAS1 (Homo sapiens) 6480464 galangin results in increased expression of EPAS1 protein CTD PMID:17973296 Epas1 Rat glutathione multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Glutathione inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein]; Glutathione inhibits more ... CTD PMID:23958427 Epas1 Rat hydralazine multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of EPAS1 mRNA CTD PMID:17183730 Epas1 Rat hydrogen peroxide multiple interactions ISO EPAS1 (Homo sapiens) 6480464 delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of EPAS1 protein] CTD PMID:18603805 Epas1 Rat hydrogen peroxide increases expression ISO EPAS1 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of EPAS1 mRNA; Hydrogen Peroxide results in increased expression more ... CTD PMID:18603805|PMID:34581912 Epas1 Rat hydrogen peroxide affects expression ISO EPAS1 (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of EPAS1 mRNA CTD PMID:20044591 Epas1 Rat ibuprofen decreases expression ISO EPAS1 (Homo sapiens) 6480464 Ibuprofen results in decreased expression of EPAS1 protein CTD PMID:12912967 Epas1 Rat indoxyl sulfate multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Indican inhibits the reaction [cobaltous chloride affects the localization of EPAS1 protein] CTD PMID:21863063 Epas1 Rat iron atom multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Iron inhibits the reaction [galangin results in increased expression of EPAS1 protein]; Iron inhibits the more ... CTD PMID:17973296 Epas1 Rat iron atom increases expression EXP 6480464 Iron deficiency results in increased expression of EPAS1 protein CTD PMID:23814049 Epas1 Rat iron(0) multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Iron inhibits the reaction [galangin results in increased expression of EPAS1 protein]; Iron inhibits the more ... CTD PMID:17973296 Epas1 Rat iron(0) increases expression EXP 6480464 Iron deficiency results in increased expression of EPAS1 protein CTD PMID:23814049 Epas1 Rat iron(2+) sulfate (anhydrous) multiple interactions ISO EPAS1 (Homo sapiens) 6480464 ferrous sulfate inhibits the reaction [galangin results in increased expression of EPAS1 protein]; ferrous sulfate more ... CTD PMID:17973296 Epas1 Rat ketoconazole increases expression ISO EPAS1 (Homo sapiens) 6480464 Ketoconazole results in increased expression of EPAS1 mRNA CTD PMID:36621641 Epas1 Rat ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of EPAS1 mRNA CTD PMID:37077353 Epas1 Rat ketorolac decreases expression ISO EPAS1 (Homo sapiens) 6480464 Ketorolac results in decreased expression of EPAS1 protein CTD PMID:12912967 Epas1 Rat L-ascorbic acid multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of EPAS1 protein] CTD PMID:16288478 Epas1 Rat L-methionine multiple interactions ISO Epas1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression more ... CTD PMID:20938992 Epas1 Rat leflunomide increases expression ISO EPAS1 (Homo sapiens) 6480464 leflunomide results in increased expression of EPAS1 mRNA CTD PMID:28988120 Epas1 Rat letrozole multiple interactions ISO Epas1 (Mus musculus) 6480464 [letrozole results in decreased abundance of Estradiol] which results in decreased expression of EPAS1 mRNA CTD PMID:19620711 Epas1 Rat LY294002 multiple interactions ISO EPAS1 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits more ... CTD PMID:23958427 Epas1 Rat manganese(II) chloride increases expression ISO Epas1 (Mus musculus) 6480464 manganese chloride results in increased expression of EPAS1 mRNA CTD PMID:17467022 Epas1 Rat menadione affects expression ISO EPAS1 (Homo sapiens) 6480464 Vitamin K 3 affects the expression of EPAS1 mRNA CTD PMID:20044591 Epas1 Rat mercury dibromide increases expression ISO EPAS1 (Homo sapiens) 6480464 mercuric bromide results in increased expression of EPAS1 mRNA CTD PMID:26272509 Epas1 Rat mercury dibromide multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Epas1 Rat methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of EPAS1 mRNA CTD PMID:32035215 Epas1 Rat methotrexate increases expression ISO EPAS1 (Homo sapiens) 6480464 Methotrexate results in increased expression of EPAS1 mRNA CTD PMID:17400583 Epas1 Rat methoxychlor affects methylation EXP 6480464 Methoxychlor affects the methylation of EPAS1 gene CTD PMID:35440735 Epas1 Rat methyl methanesulfonate increases expression ISO EPAS1 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of EPAS1 mRNA CTD PMID:23649840 Epas1 Rat mithramycin decreases expression EXP 6480464 Plicamycin results in decreased expression of EPAS1 mRNA CTD PMID:23814049 Epas1 Rat molibresib increases expression ISO EPAS1 (Homo sapiens) 6480464 molibresib results in increased expression of EPAS1 mRNA CTD PMID:27292261 Epas1 Rat molibresib multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Oxygen deficiency co-treated with molibresib] results in increased expression of EPAS1 mRNA CTD PMID:27292261 Epas1 Rat myxothiazol multiple interactions EXP 6480464 myxothiazol inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:18353899 Epas1 Rat N-acetyl-L-cysteine multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein]; Acetylcysteine inhibits more ... CTD PMID:23958427 Epas1 Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen inhibits the reaction [AQP3 protein results in increased stability more ... CTD PMID:23545307 Epas1 Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO EPAS1 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EPAS1 protein CTD PMID:35504338 Epas1 Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases hydroxylation ISO EPAS1 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased hydroxylation of EPAS1 protein CTD PMID:26735578 Epas1 Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Formaldehyde co-treated with pevonedistat co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the folding of EPAS1 protein; [Formaldehyde more ... CTD PMID:22447124|PMID:26735578|PMID:35504338 Epas1 Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases ubiquitination ISO EPAS1 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of EPAS1 protein CTD PMID:22447124 Epas1 Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases stability EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of EPAS1 protein CTD PMID:23545307 Epas1 Rat N-methyl-4-phenylpyridinium decreases expression ISO EPAS1 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of EPAS1 mRNA CTD PMID:25234470 Epas1 Rat N-methyl-4-phenylpyridinium increases expression ISO EPAS1 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of EPAS1 mRNA CTD PMID:25234470 Epas1 Rat nickel atom multiple interactions ISO Epas1 (Mus musculus) 6480464 EPAS1 protein affects the reaction [Nickel results in increased abundance of Nitric Oxide] CTD PMID:23788631 Epas1 Rat nickel sulfate increases stability ISO EPAS1 (Homo sapiens) 6480464 nickel sulfate results in increased stability of EPAS1 protein CTD PMID:20046830 Epas1 Rat nickel sulfate multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [nickel sulfate results in decreased expression more ... CTD PMID:16288478|PMID:20046830 Epas1 Rat nickel sulfate increases expression ISO EPAS1 (Homo sapiens) 6480464 nickel sulfate results in increased expression of EPAS1 mRNA; nickel sulfate results in increased expression more ... CTD PMID:16288478|PMID:22714537 Epas1 Rat niclosamide multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Niclosamide inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:36318118 Epas1 Rat nitric oxide multiple interactions ISO Epas1 (Mus musculus) 6480464 EPAS1 protein affects the reaction [Cobalt results in increased abundance of Nitric Oxide]; EPAS1 protein more ... CTD PMID:23788631 Epas1 Rat nitrofen decreases expression EXP 6480464 nitrofen results in decreased expression of EPAS1 mRNA CTD PMID:20638522 Epas1 Rat Nor-9-carboxy-delta9-THC multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Cannabinoids results in increased abundance of 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid] which affects the methylation of EPAS1 gene CTD PMID:30521419 Epas1 Rat ochratoxin A multiple interactions ISO EPAS1 (Homo sapiens) 6480464 EPAS1 protein inhibits the reaction [ochratoxin A results in decreased expression of VEGFA protein] CTD PMID:21554934 Epas1 Rat ochratoxin A decreases expression ISO EPAS1 (Homo sapiens) 6480464 ochratoxin A results in decreased expression of EPAS1 protein CTD PMID:21554934 Epas1 Rat okadaic acid increases expression ISO EPAS1 (Homo sapiens) 6480464 Okadaic Acid results in increased expression of EPAS1 mRNA CTD PMID:28939011 Epas1 Rat ozone decreases expression EXP 6480464 Ozone results in decreased expression of EPAS1 mRNA CTD PMID:28549673 Epas1 Rat ozone multiple interactions ISO Epas1 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ... CTD PMID:34911549 Epas1 Rat panobinostat increases expression ISO EPAS1 (Homo sapiens) 6480464 panobinostat results in increased expression of EPAS1 mRNA CTD PMID:26272509 Epas1 Rat panobinostat multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... CTD PMID:27188386 Epas1 Rat paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of EPAS1 mRNA CTD PMID:33387578 Epas1 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Epas1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of EPAS1 mRNA CTD PMID:36331819 Epas1 Rat perfluorooctanoic acid multiple interactions EXP 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of EPAS1 mRNA CTD PMID:35163327 Epas1 Rat pevonedistat multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Formaldehyde co-treated with pevonedistat co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the folding of EPAS1 protein CTD PMID:35504338 Epas1 Rat phenylephrine decreases expression EXP 6480464 Phenylephrine results in decreased expression of EPAS1 mRNA CTD PMID:18158353 Epas1 Rat phenylmercury acetate increases expression ISO EPAS1 (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of EPAS1 mRNA CTD PMID:26272509 Epas1 Rat phenylmercury acetate multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Epas1 Rat phorbol 13-acetate 12-myristate multiple interactions ISO Epas1 (Mus musculus) 6480464 [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of EPAS1 mRNA CTD PMID:23519560 Epas1 Rat phosphane increases expression EXP 6480464 phosphine results in increased expression of EPAS1 mRNA CTD PMID:34427094 Epas1 Rat pirinixic acid increases expression ISO Epas1 (Mus musculus) 6480464 pirinixic acid results in increased expression of EPAS1 mRNA CTD PMID:17426115|PMID:18301758 Epas1 Rat piroxicam decreases expression ISO EPAS1 (Homo sapiens) 6480464 Piroxicam results in decreased expression of EPAS1 mRNA CTD PMID:21858171 Epas1 Rat pregnenolone 16alpha-carbonitrile increases expression ISO Epas1 (Mus musculus) 6480464 Pregnenolone Carbonitrile results in increased expression of EPAS1 mRNA CTD PMID:28903501 Epas1 Rat protoporphyrin affects localization ISO EPAS1 (Homo sapiens) 6480464 protoporphyrin IX affects the localization of EPAS1 protein CTD PMID:23624237 Epas1 Rat quercetin multiple interactions ISO EPAS1 (Homo sapiens) 6480464 ferrous sulfate inhibits the reaction [Quercetin results in increased expression of EPAS1 protein]; Iron inhibits more ... CTD PMID:17973296 Epas1 Rat quercetin increases expression ISO EPAS1 (Homo sapiens) 6480464 Quercetin results in increased expression of EPAS1 protein CTD PMID:17973296 Epas1 Rat quercitrin increases expression ISO EPAS1 (Homo sapiens) 6480464 quercitrin results in increased expression of EPAS1 mRNA CTD PMID:25193878 Epas1 Rat rifampicin multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Rifampin co-treated with NR1I2 protein] results in increased expression of EPAS1 mRNA CTD PMID:21127053 Epas1 Rat rotenone multiple interactions EXP 6480464 Rotenone inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:18353899 Epas1 Rat rotenone decreases expression ISO EPAS1 (Homo sapiens) 6480464 Rotenone results in decreased expression of EPAS1 mRNA CTD PMID:29955902 Epas1 Rat SB 431542 multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Epas1 Rat silicon dioxide increases expression ISO EPAS1 (Homo sapiens) 6480464 Silicon Dioxide analog results in increased expression of EPAS1 mRNA CTD PMID:25895662 Epas1 Rat silver atom decreases expression ISO Epas1 (Mus musculus) 6480464 Silver results in decreased expression of EPAS1 mRNA CTD PMID:27131904 Epas1 Rat silver(0) decreases expression ISO Epas1 (Mus musculus) 6480464 Silver results in decreased expression of EPAS1 mRNA CTD PMID:27131904 Epas1 Rat sodium arsenite multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [MALAT1 mRNA affects the susceptibility to sodium arsenite] which results in decreased hydroxylation of EPAS1 more ... CTD PMID:22662215|PMID:26735578|PMID:29277653|PMID:30090327|PMID:30334557 Epas1 Rat sodium arsenite increases expression ISO Epas1 (Mus musculus) 6480464 sodium arsenite results in increased expression of EPAS1 protein CTD PMID:26735578 Epas1 Rat sodium arsenite increases expression ISO EPAS1 (Homo sapiens) 6480464 sodium arsenite results in increased expression of EPAS1 mRNA; sodium arsenite results in increased expression more ... CTD PMID:22662215|PMID:22714537|PMID:27287256|PMID:29277653|PMID:30090327|PMID:30334557|PMID:34032870 Epas1 Rat sodium arsenite affects response to substance ISO EPAS1 (Homo sapiens) 6480464 EPAS1 protein affects the susceptibility to sodium arsenite CTD PMID:23333640 Epas1 Rat sodium cyanide multiple interactions EXP 6480464 Sodium Cyanide inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:18353899 Epas1 Rat sotorasib multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EPAS1 mRNA CTD PMID:36139627 Epas1 Rat squalene decreases expression ISO EPAS1 (Homo sapiens) 6480464 Squalene results in decreased expression of EPAS1 mRNA; Squalene results in decreased expression of EPAS1 more ... CTD PMID:33219891 Epas1 Rat sunitinib decreases expression ISO EPAS1 (Homo sapiens) 6480464 Sunitinib results in decreased expression of EPAS1 mRNA CTD PMID:31533062 Epas1 Rat T-2 toxin multiple interactions ISO Epas1 (Mus musculus) 6480464 BAY 11-7085 inhibits the reaction [T-2 Toxin results in increased expression of EPAS1 mRNA]; BAY more ... CTD PMID:22800716 Epas1 Rat T-2 toxin increases expression ISO EPAS1 (Homo sapiens) 6480464 T-2 Toxin results in increased expression of EPAS1 mRNA CTD PMID:34581912 Epas1 Rat T-2 toxin increases expression ISO Epas1 (Mus musculus) 6480464 T-2 Toxin results in increased expression of EPAS1 mRNA; T-2 Toxin results in increased expression more ... CTD PMID:22800716 Epas1 Rat temozolomide decreases expression ISO EPAS1 (Homo sapiens) 6480464 Temozolomide results in decreased expression of EPAS1 mRNA CTD PMID:31758290 Epas1 Rat thapsigargin decreases expression ISO EPAS1 (Homo sapiens) 6480464 Thapsigargin results in decreased expression of EPAS1 mRNA CTD PMID:22378314 Epas1 Rat titanium dioxide decreases methylation ISO Epas1 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of EPAS1 gene CTD PMID:35295148 Epas1 Rat titanium dioxide increases methylation ISO Epas1 (Mus musculus) 6480464 titanium dioxide results in increased methylation of EPAS1 promoter CTD PMID:35295148 Epas1 Rat topotecan multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Topotecan inhibits the reaction [sodium arsenite results in increased expression of EPAS1 protein] CTD PMID:30090327 Epas1 Rat trametinib multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EPAS1 mRNA CTD PMID:36139627 Epas1 Rat trichloroethene decreases expression ISO Epas1 (Mus musculus) 6480464 Trichloroethylene results in decreased expression of EPAS1 mRNA CTD PMID:19448997 Epas1 Rat trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of EPAS1 mRNA CTD PMID:33387578 Epas1 Rat trichloroethene increases expression ISO Epas1 (Mus musculus) 6480464 Trichloroethylene results in increased expression of EPAS1 mRNA CTD PMID:15363585 Epas1 Rat trichostatin A increases expression ISO EPAS1 (Homo sapiens) 6480464 trichostatin A results in increased expression of EPAS1 mRNA CTD PMID:24935251|PMID:26272509|PMID:28542535 Epas1 Rat trichostatin A multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Epas1 Rat triphenyl phosphate affects expression ISO EPAS1 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of EPAS1 mRNA CTD PMID:37042841 Epas1 Rat triptonide increases expression ISO Epas1 (Mus musculus) 6480464 triptonide results in increased expression of EPAS1 mRNA CTD PMID:33045310 Epas1 Rat troglitazone decreases expression ISO Epas1 (Mus musculus) 6480464 troglitazone results in decreased expression of EPAS1 mRNA CTD PMID:28973697 Epas1 Rat tunicamycin decreases expression ISO EPAS1 (Homo sapiens) 6480464 Tunicamycin results in decreased expression of EPAS1 mRNA CTD PMID:22378314 Epas1 Rat valproic acid multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of EPAS1 mRNA; [NOG protein co-treated more ... CTD PMID:17183730|PMID:27188386 Epas1 Rat valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of EPAS1 mRNA CTD PMID:29427782 Epas1 Rat valproic acid increases expression ISO EPAS1 (Homo sapiens) 6480464 Valproic Acid results in increased expression of EPAS1 mRNA CTD PMID:23179753|PMID:24383497|PMID:24935251|PMID:26272509|PMID:28001369 Epas1 Rat valproic acid affects expression ISO Epas1 (Mus musculus) 6480464 Valproic Acid affects the expression of EPAS1 mRNA CTD PMID:17292431 Epas1 Rat vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of EPAS1 mRNA CTD PMID:19015723 Epas1 Rat vinclozolin increases methylation EXP 6480464 vinclozolin results in increased methylation of EPAS1 gene CTD PMID:31079544 Epas1 Rat vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of EPAS1 mRNA CTD PMID:30207508 Epas1 Rat vorinostat decreases expression ISO EPAS1 (Homo sapiens) 6480464 vorinostat results in decreased expression of EPAS1 mRNA CTD PMID:18769122 Epas1 Rat zearalenone increases expression ISO Epas1 (Mus musculus) 6480464 Zearalenone results in increased expression of EPAS1 mRNA CTD PMID:30138655