1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO RGD:68595 6480464 [3 more ... CTD PMID:19679656 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of EPAS1 mRNA CTD PMID:17351261 17beta-estradiol multiple interactions ISO RGD:68594 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of EPAS1 mRNA, EGF protein inhibits the reaction [Estradiol results in decreased expression of EPAS1 mRNA] CTD PMID:24758408 , PMID:30165855 17beta-estradiol multiple interactions ISO RGD:68595 6480464 [letrozole results in decreased abundance of Estradiol] which results in decreased expression of EPAS1 mRNA CTD PMID:19620711 17beta-estradiol decreases expression ISO RGD:68594 6480464 Estradiol results in decreased expression of EPAS1 mRNA CTD PMID:24758408 more ... 1H-benzimidazole increases stability EXP 6480464 benzimidazole results in increased stability of EPAS1 protein CTD PMID:23545307 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:68595 6480464 Tetrachlorodibenzodioxin affects the expression of EPAS1 mRNA CTD PMID:16962184 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:68595 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to EPAS1 gene] CTD PMID:28213091 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of EPAS1 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:68595 6480464 Tetrachlorodibenzodioxin results in decreased expression of EPAS1 mRNA CTD PMID:19933214 , PMID:28213091 2-amino-2-deoxy-D-glucopyranose decreases expression EXP 6480464 Glucosamine results in decreased expression of EPAS1 mRNA CTD PMID:17109745 2-amino-2-deoxy-D-glucopyranose multiple interactions EXP 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA], IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA] CTD PMID:17109745 2-methylcholine affects expression ISO RGD:68594 6480464 beta-methylcholine affects the expression of EPAS1 mRNA CTD PMID:21179406 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:23196670 3,3',5-triiodo-L-thyronine increases expression ISO RGD:68595 6480464 Triiodothyronine results in increased expression of EPAS1 mRNA CTD PMID:25172293 3,4-dihydroxybenzoate increases expression ISO RGD:68595 6480464 3, 4-dihydroxybenzoate results in increased expression of EPAS1 mRNA CTD PMID:19679656 3,4-dihydroxybenzoate multiple interactions ISO RGD:68595 6480464 [3 more ... CTD PMID:19679656 3-methylcholanthrene multiple interactions ISO RGD:68595 6480464 [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of EPAS1 mRNA CTD PMID:23519560 3-phenylprop-2-enal increases expression ISO RGD:68594 6480464 cinnamic aldehyde results in increased expression of EPAS1 mRNA CTD PMID:19524605 4,4'-diaminodiphenylmethane increases expression ISO RGD:68595 6480464 4, 4'-diaminodiphenylmethane results in increased expression of EPAS1 mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol multiple interactions ISO RGD:68595 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Tretinoin] results in decreased expression of EPAS1 mRNA CTD PMID:30951980 4,4'-sulfonyldiphenol increases expression ISO RGD:68595 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of EPAS1 mRNA CTD PMID:30951980 4-amino-2,6-dinitrotoluene affects expression EXP 6480464 4-amino-2, 6-dinitrotoluene affects the expression of EPAS1 mRNA CTD PMID:21346803 4-hydroperoxycyclophosphamide increases expression ISO RGD:68595 6480464 perfosfamide results in increased expression of EPAS1 protein CTD PMID:23251655 5-fluorouracil increases expression ISO RGD:68594 6480464 Fluorouracil results in increased expression of EPAS1 mRNA CTD PMID:16557594 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of EPAS1 mRNA CTD PMID:24780913 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of EPAS1 mRNA CTD PMID:31881176 actinomycin D increases stability EXP 6480464 Dactinomycin results in increased stability of EPAS1 protein CTD PMID:23545307 aflatoxin B1 increases methylation ISO RGD:68594 6480464 Aflatoxin B1 results in increased methylation of EPAS1 gene, Aflatoxin B1 results in increased methylation of EPAS1 intron CTD PMID:27153756 , PMID:30157460 aflatoxin B2 increases methylation ISO RGD:68594 6480464 aflatoxin B2 results in increased methylation of EPAS1 intron CTD PMID:30157460 aldehydo-D-glucosamine decreases expression EXP 6480464 Glucosamine results in decreased expression of EPAS1 mRNA CTD PMID:17109745 aldehydo-D-glucosamine multiple interactions EXP 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA], IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA] CTD PMID:17109745 all-trans-retinoic acid increases expression ISO RGD:68594 6480464 Tretinoin results in increased expression of EPAS1 mRNA CTD PMID:15894607 more ... all-trans-retinoic acid multiple interactions ISO RGD:68595 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Tretinoin] results in decreased expression of EPAS1 mRNA CTD PMID:30951980 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of EPAS1 mRNA CTD PMID:16483693 antimycin A multiple interactions EXP 6480464 Antimycin A inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:18353899 aristolochic acid increases expression ISO RGD:68594 6480464 aristolochic acid I results in increased expression of EPAS1 protein CTD PMID:21554934 atrazine decreases expression ISO RGD:68594 6480464 Atrazine results in decreased expression of EPAS1 mRNA CTD PMID:22378314 benzo[a]pyrene decreases expression ISO RGD:68595 6480464 Benzo(a)pyrene results in decreased expression of EPAS1 mRNA CTD PMID:19770486 , PMID:22228805 benzo[a]pyrene decreases expression ISO RGD:68594 6480464 Benzo(a)pyrene results in decreased expression of EPAS1 mRNA CTD PMID:30453624 benzo[a]pyrene increases expression ISO RGD:68595 6480464 Benzo(a)pyrene results in increased expression of EPAS1 mRNA CTD PMID:22228805 , PMID:23735875 benzo[a]pyrene affects response to substance ISO RGD:68594 6480464 EPAS1 protein affects the susceptibility to Benzo(a)pyrene CTD PMID:23333640 benzo[a]pyrene diol epoxide I increases expression ISO RGD:68594 6480464 7 more ... CTD PMID:20382639 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:68594 6480464 7 more ... CTD PMID:19150397 beta-D-glucosamine decreases expression EXP 6480464 Glucosamine results in decreased expression of EPAS1 mRNA CTD PMID:17109745 beta-D-glucosamine multiple interactions EXP 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA], IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA] CTD PMID:17109745 bis(2-chloroethyl) sulfide increases expression ISO RGD:68595 6480464 Mustard Gas results in increased expression of EPAS1 mRNA CTD PMID:15674843 bis(2-ethylhexyl) phthalate increases expression ISO RGD:68594 6480464 Diethylhexyl Phthalate results in increased expression of EPAS1 mRNA CTD PMID:31163220 bisphenol A decreases expression ISO RGD:68594 6480464 bisphenol A results in decreased expression of EPAS1 mRNA CTD PMID:28711546 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of EPAS1 mRNA CTD PMID:30816183 bisphenol A affects expression ISO RGD:68594 6480464 bisphenol A affects the expression of EPAS1 mRNA CTD PMID:30903817 bisphenol A increases expression ISO RGD:68594 6480464 bisphenol A results in increased expression of EPAS1 mRNA CTD PMID:29275510 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of EPAS1 gene CTD PMID:28505145 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of EPAS1 mRNA CTD PMID:25181051 Bisphenol B decreases expression ISO RGD:68594 6480464 bisphenol B results in decreased expression of EPAS1 mRNA CTD PMID:28591870 bisphenol F decreases expression ISO RGD:68594 6480464 bisphenol F results in decreased expression of EPAS1 mRNA CTD PMID:28591870 butan-1-ol multiple interactions ISO RGD:68594 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of EPAS1 mRNA CTD PMID:29432896 cadmium dichloride increases methylation EXP 6480464 Cadmium Chloride results in increased methylation of EPAS1 promoter CTD PMID:22457795 carbon nanotube decreases expression ISO RGD:68595 6480464 Nanotubes, Carbon analog results in decreased expression of EPAS1 mRNA, Nanotubes, Carbon results in decreased expression of EPAS1 mRNA CTD PMID:25554681 chloropicrin affects expression ISO RGD:68594 6480464 chloropicrin affects the expression of EPAS1 mRNA CTD PMID:26352163 chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of EPAS1 mRNA CTD PMID:18668222 choline multiple interactions ISO RGD:68595 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of EPAS1 mRNA, [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EPAS1 gene CTD PMID:20938992 chromium(6+) affects expression ISO RGD:68595 6480464 chromium hexavalent ion affects the expression of EPAS1 mRNA CTD PMID:28472532 ciglitazone multiple interactions ISO RGD:68594 6480464 [ciglitazone binds to PPARG protein] which results in increased expression of EPAS1 mRNA CTD PMID:16197558 clofibrate decreases expression ISO RGD:68595 6480464 Clofibrate results in decreased expression of EPAS1 mRNA CTD PMID:23811191 cobalt atom multiple interactions ISO RGD:68595 6480464 EPAS1 protein affects the reaction [Cobalt results in increased abundance of Nitric Oxide] CTD PMID:23788631 cobalt atom increases expression EXP 6480464 Cobalt results in increased expression of EPAS1 protein CTD PMID:17967803 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of EPAS1 protein CTD PMID:21558026 , PMID:23545307 cobalt dichloride increases expression ISO RGD:68595 6480464 cobaltous chloride results in increased expression of EPAS1 protein CTD PMID:24503013 cobalt dichloride increases stability ISO RGD:68594 6480464 cobaltous chloride results in increased stability of EPAS1 protein CTD PMID:18515279 cobalt dichloride increases expression ISO RGD:68594 6480464 cobaltous chloride results in increased expression of EPAS1 protein CTD PMID:21036805 more ... cobalt dichloride affects localization ISO RGD:68594 6480464 cobaltous chloride affects the localization of EPAS1 protein CTD PMID:21863063 cobalt dichloride increases response to substance ISO RGD:68594 6480464 EPAS1 protein results in increased susceptibility to cobaltous chloride CTD PMID:25805230 cobalt dichloride multiple interactions EXP 6480464 [AQP1 protein results in increased stability of EPAS1 protein] promotes the reaction [cobaltous chloride results in increased expression of EPAS1 protein] more ... CTD PMID:23545307 cobalt dichloride multiple interactions ISO RGD:68594 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein] more ... CTD PMID:21863063 more ... copper atom multiple interactions ISO RGD:68595 6480464 EPAS1 gene mutant form inhibits the reaction [Copper deficiency results in increased expression of CYBRD1 mRNA] more ... CTD PMID:23555700 copper atom increases expression EXP 6480464 Copper results in increased expression of EPAS1 mRNA CTD PMID:30556269 copper atom increases expression ISO RGD:68595 6480464 Copper deficiency results in increased expression of EPAS1 protein CTD PMID:23555700 copper(0) multiple interactions ISO RGD:68595 6480464 EPAS1 gene mutant form inhibits the reaction [Copper deficiency results in increased expression of CYBRD1 mRNA] more ... CTD PMID:23555700 copper(0) increases expression EXP 6480464 Copper results in increased expression of EPAS1 mRNA CTD PMID:30556269 copper(0) increases expression ISO RGD:68595 6480464 Copper deficiency results in increased expression of EPAS1 protein CTD PMID:23555700 copper(II) sulfate increases expression ISO RGD:68594 6480464 Copper Sulfate results in increased expression of EPAS1 mRNA CTD PMID:19549813 crocidolite asbestos increases expression ISO RGD:68594 6480464 Asbestos, Crocidolite results in increased expression of EPAS1 mRNA CTD PMID:18687144 curcumin multiple interactions ISO RGD:68594 6480464 Curcumin analog inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:20554536 cycloheximide multiple interactions ISO RGD:68594 6480464 Cycloheximide inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein], Cycloheximide inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:23958427 cyclosporin A decreases expression ISO RGD:68594 6480464 Cyclosporine results in decreased expression of EPAS1 mRNA CTD PMID:20106945 , PMID:27989131 cyclosporin A increases expression ISO RGD:68594 6480464 Cyclosporine results in increased expression of EPAS1 mRNA CTD PMID:25562108 cyclosporin A decreases expression ISO RGD:68595 6480464 Cyclosporine results in decreased expression of EPAS1 mRNA CTD PMID:19770486 DDT decreases expression EXP 6480464 DDT results in decreased expression of EPAS1 mRNA CTD PMID:30207508 Deguelin decreases expression ISO RGD:68594 6480464 deguelin results in decreased expression of EPAS1 protein CTD PMID:19336726 delphinidin multiple interactions ISO RGD:68594 6480464 delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of EPAS1 protein] CTD PMID:18603805 desferrioxamine B multiple interactions ISO RGD:68594 6480464 Deferoxamine inhibits the reaction [EPAS1 protein results in increased degradation of COX4I1 protein] CTD PMID:18515279 desferrioxamine B increases expression EXP 6480464 Deferoxamine results in increased expression of EPAS1 protein CTD PMID:18353899 , PMID:21558026 desferrioxamine B increases expression ISO RGD:68594 6480464 Deferoxamine results in increased expression of EPAS1 protein CTD PMID:27287256 desferrioxamine B increases stability ISO RGD:68594 6480464 Deferoxamine results in increased stability of EPAS1 protein CTD PMID:18515279 diazinon increases methylation ISO RGD:68594 6480464 Diazinon results in increased methylation of EPAS1 gene CTD PMID:22964155 diclofenac decreases expression ISO RGD:68594 6480464 Diclofenac results in decreased expression of EPAS1 protein CTD PMID:12912967 dicrotophos increases expression ISO RGD:68594 6480464 dicrotophos results in increased expression of EPAS1 mRNA CTD PMID:28302478 diethyl malate affects expression ISO RGD:68595 6480464 diethyl malate affects the expression of EPAS1 mRNA CTD PMID:24814887 dinophysistoxin 1 increases expression ISO RGD:68594 6480464 dinophysistoxin 1 results in increased expression of EPAS1 mRNA CTD PMID:28939011 dioxygen multiple interactions ISO RGD:68594 6480464 1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1 more ... CTD PMID:20046830 more ... dioxygen increases expression ISO RGD:68595 6480464 Oxygen deficiency results in increased expression of EPAS1 protein CTD PMID:24503013 , PMID:26723917 dioxygen affects localization ISO RGD:68594 6480464 Oxygen deficiency affects the localization of EPAS1 protein CTD PMID:24755467 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of EPAS1 protein CTD PMID:18353899 , PMID:23545307 dioxygen increases expression ISO RGD:68594 6480464 Oxygen deficiency results in increased expression of EPAS1 mRNA, Oxygen deficiency results in increased expression of EPAS1 protein CTD PMID:20554536 more ... dioxygen multiple interactions ISO RGD:68595 6480464 Oxygen deficiency affects the localization of and results in increased activity of EPAS1 protein CTD PMID:20880076 dioxygen affects response to substance EXP 6480464 EPAS1 protein affects the susceptibility to Oxygen deficiency CTD PMID:12679337 dioxygen multiple interactions EXP 6480464 [AQP1 protein results in increased stability of EPAS1 protein] promotes the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] more ... CTD PMID:12679337 more ... disodium selenite increases expression ISO RGD:68594 6480464 Sodium Selenite results in increased expression of EPAS1 mRNA CTD PMID:24383545 dorsomorphin multiple interactions ISO RGD:68594 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin decreases expression ISO RGD:68595 6480464 Doxorubicin results in decreased expression of EPAS1 mRNA CTD PMID:26873546 doxorubicin decreases expression ISO RGD:68594 6480464 Doxorubicin results in decreased expression of EPAS1 mRNA CTD PMID:29803840 ethanol multiple interactions ISO RGD:68594 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of EPAS1 mRNA CTD PMID:29432896 ethanol increases expression ISO RGD:68595 6480464 Ethanol results in increased expression of EPAS1 mRNA CTD PMID:30319688 ethanol affects splicing ISO RGD:68595 6480464 Ethanol affects the splicing of EPAS1 mRNA CTD PMID:30319688 fenamidone increases expression ISO RGD:68595 6480464 fenamidone results in increased expression of EPAS1 mRNA CTD PMID:27029645 flutamide increases expression EXP 6480464 Flutamide results in increased expression of EPAS1 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:68595 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of EPAS1 mRNA, [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EPAS1 gene CTD PMID:20938992 furan increases expression ISO RGD:68595 6480464 furan results in increased expression of EPAS1 mRNA CTD PMID:24183702 galangin multiple interactions ISO RGD:68594 6480464 ferrous sulfate inhibits the reaction [galangin results in increased expression of EPAS1 protein], Iron inhibits the reaction [galangin results in increased expression of EPAS1 protein] CTD PMID:17973296 galangin increases expression ISO RGD:68594 6480464 galangin results in increased expression of EPAS1 protein CTD PMID:17973296 glutathione multiple interactions ISO RGD:68594 6480464 Glutathione inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein], Glutathione inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:23958427 hydralazine multiple interactions ISO RGD:68594 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of EPAS1 mRNA CTD PMID:17183730 hydrogen peroxide multiple interactions ISO RGD:68594 6480464 delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of EPAS1 protein] CTD PMID:18603805 hydrogen peroxide increases expression ISO RGD:68594 6480464 Hydrogen Peroxide results in increased expression of EPAS1 protein CTD PMID:18603805 hydrogen peroxide affects expression ISO RGD:68594 6480464 Hydrogen Peroxide affects the expression of EPAS1 mRNA CTD PMID:20044591 ibuprofen decreases expression ISO RGD:68594 6480464 Ibuprofen results in decreased expression of EPAS1 protein CTD PMID:12912967 indoxyl sulfate multiple interactions ISO RGD:68594 6480464 Indican inhibits the reaction [cobaltous chloride affects the localization of EPAS1 protein] CTD PMID:21863063 iron atom multiple interactions ISO RGD:68594 6480464 Iron inhibits the reaction [galangin results in increased expression of EPAS1 protein], Iron inhibits the reaction [Quercetin results in increased expression of EPAS1 protein] CTD PMID:17973296 iron atom increases expression EXP 6480464 Iron deficiency results in increased expression of EPAS1 protein CTD PMID:23814049 iron(0) multiple interactions ISO RGD:68594 6480464 Iron inhibits the reaction [galangin results in increased expression of EPAS1 protein], Iron inhibits the reaction [Quercetin results in increased expression of EPAS1 protein] CTD PMID:17973296 iron(0) increases expression EXP 6480464 Iron deficiency results in increased expression of EPAS1 protein CTD PMID:23814049 iron(2+) sulfate (anhydrous) multiple interactions ISO RGD:68594 6480464 ferrous sulfate inhibits the reaction [galangin results in increased expression of EPAS1 protein], ferrous sulfate inhibits the reaction [Quercetin results in increased expression of EPAS1 protein] CTD PMID:17973296 ketorolac decreases expression ISO RGD:68594 6480464 Ketorolac results in decreased expression of EPAS1 protein CTD PMID:12912967 L-ascorbic acid multiple interactions ISO RGD:68594 6480464 Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of EPAS1 protein] CTD PMID:16288478 L-methionine multiple interactions ISO RGD:68595 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of EPAS1 mRNA, [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EPAS1 gene CTD PMID:20938992 leflunomide increases expression ISO RGD:68594 6480464 leflunomide results in increased expression of EPAS1 mRNA CTD PMID:28988120 letrozole multiple interactions ISO RGD:68595 6480464 [letrozole results in decreased abundance of Estradiol] which results in decreased expression of EPAS1 mRNA CTD PMID:19620711 LY294002 multiple interactions ISO RGD:68594 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:23958427 manganese(II) chloride increases expression ISO RGD:68595 6480464 manganese chloride results in increased expression of EPAS1 mRNA CTD PMID:17467022 menadione affects expression ISO RGD:68594 6480464 Vitamin K 3 affects the expression of EPAS1 mRNA CTD PMID:20044591 mercury dibromide increases expression ISO RGD:68594 6480464 mercuric bromide results in increased expression of EPAS1 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:68594 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPAS1 mRNA CTD PMID:27188386 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of EPAS1 mRNA CTD PMID:32035215 methotrexate increases expression ISO RGD:68594 6480464 Methotrexate results in increased expression of EPAS1 mRNA CTD PMID:17400583 methyl methanesulfonate increases expression ISO RGD:68594 6480464 Methyl Methanesulfonate results in increased expression of EPAS1 mRNA CTD PMID:23649840 mithramycin decreases expression EXP 6480464 Plicamycin results in decreased expression of EPAS1 mRNA CTD PMID:23814049 myxothiazol multiple interactions EXP 6480464 myxothiazol inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:18353899 N-acetyl-L-cysteine multiple interactions ISO RGD:68594 6480464 Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein], Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:23958427 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen inhibits the reaction [AQP3 protein results in increased stability of EPAS1 protein]], benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen inhibits the reaction [AQP5 protein results in increased stability of EPAS1 protein]] CTD PMID:23545307 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases stability EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of EPAS1 protein CTD PMID:23545307 N-methyl-4-phenylpyridinium decreases expression ISO RGD:68594 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of EPAS1 mRNA CTD PMID:25234470 N-methyl-4-phenylpyridinium increases expression ISO RGD:68594 6480464 1-Methyl-4-phenylpyridinium results in increased expression of EPAS1 mRNA CTD PMID:25234470 nickel atom multiple interactions ISO RGD:68595 6480464 EPAS1 protein affects the reaction [Nickel results in increased abundance of Nitric Oxide] CTD PMID:23788631 nickel sulfate increases stability ISO RGD:68594 6480464 nickel sulfate results in increased stability of EPAS1 protein CTD PMID:20046830 nickel sulfate multiple interactions ISO RGD:68594 6480464 [HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [nickel sulfate results in decreased expression of USP28 protein] more ... CTD PMID:16288478 , PMID:20046830 nickel sulfate increases expression ISO RGD:68594 6480464 nickel sulfate results in increased expression of EPAS1 mRNA, nickel sulfate results in increased expression of EPAS1 protein CTD PMID:16288478 , PMID:22714537 nitric oxide multiple interactions ISO RGD:68595 6480464 EPAS1 protein affects the reaction [Cobalt results in increased abundance of Nitric Oxide], EPAS1 protein affects the reaction [Nickel results in increased abundance of Nitric Oxide] CTD PMID:23788631 nitrofen decreases expression EXP 6480464 nitrofen results in decreased expression of EPAS1 mRNA CTD PMID:20638522 ochratoxin A multiple interactions ISO RGD:68594 6480464 EPAS1 protein inhibits the reaction [ochratoxin A results in decreased expression of VEGFA protein] CTD PMID:21554934 ochratoxin A decreases expression ISO RGD:68594 6480464 ochratoxin A results in decreased expression of EPAS1 protein CTD PMID:21554934 okadaic acid increases expression ISO RGD:68594 6480464 Okadaic Acid results in increased expression of EPAS1 mRNA CTD PMID:28939011 panobinostat increases expression ISO RGD:68594 6480464 panobinostat results in increased expression of EPAS1 mRNA CTD PMID:26272509 panobinostat multiple interactions ISO RGD:68594 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPAS1 mRNA CTD PMID:27188386 phenylephrine decreases expression EXP 6480464 Phenylephrine results in decreased expression of EPAS1 mRNA CTD PMID:18158353 phenylmercury acetate increases expression ISO RGD:68594 6480464 Phenylmercuric Acetate results in increased expression of EPAS1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:68594 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPAS1 mRNA CTD PMID:27188386 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:68595 6480464 [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of EPAS1 mRNA CTD PMID:23519560 pirinixic acid increases expression ISO RGD:68595 6480464 pirinixic acid results in increased expression of EPAS1 mRNA CTD PMID:17426115 , PMID:18301758 piroxicam decreases expression ISO RGD:68594 6480464 Piroxicam results in decreased expression of EPAS1 mRNA CTD PMID:21858171 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:68595 6480464 Pregnenolone Carbonitrile results in increased expression of EPAS1 mRNA CTD PMID:28903501 protoporphyrin affects localization ISO RGD:68594 6480464 protoporphyrin IX affects the localization of EPAS1 protein CTD PMID:23624237 quercetin multiple interactions ISO RGD:68594 6480464 ferrous sulfate inhibits the reaction [Quercetin results in increased expression of EPAS1 protein], Iron inhibits the reaction [Quercetin results in increased expression of EPAS1 protein] CTD PMID:17973296 quercetin increases expression ISO RGD:68594 6480464 Quercetin results in increased expression of EPAS1 protein CTD PMID:17973296 quercitrin increases expression ISO RGD:68594 6480464 quercitrin results in increased expression of EPAS1 mRNA CTD PMID:25193878 rifampicin multiple interactions ISO RGD:68594 6480464 [Rifampin co-treated with NR1I2 protein] results in increased expression of EPAS1 mRNA CTD PMID:21127053 rotenone multiple interactions EXP 6480464 Rotenone inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:18353899 rotenone decreases expression ISO RGD:68594 6480464 Rotenone results in decreased expression of EPAS1 mRNA CTD PMID:29955902 SB 431542 multiple interactions ISO RGD:68594 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 silicon dioxide increases expression ISO RGD:68594 6480464 Silicon Dioxide analog results in increased expression of EPAS1 mRNA CTD PMID:25895662 silver atom decreases expression ISO RGD:68595 6480464 Silver results in decreased expression of EPAS1 mRNA CTD PMID:27131904 silver(0) decreases expression ISO RGD:68595 6480464 Silver results in decreased expression of EPAS1 mRNA CTD PMID:27131904 sodium arsenite multiple interactions ISO RGD:68594 6480464 [MIR182 mRNA affects the susceptibility to sodium arsenite] which affects the expression of EPAS1 mRNA more ... CTD PMID:22662215 more ... sodium arsenite increases expression ISO RGD:68594 6480464 sodium arsenite results in increased expression of EPAS1 mRNA, sodium arsenite results in increased expression of EPAS1 protein CTD PMID:22662215 more ... sodium arsenite affects response to substance ISO RGD:68594 6480464 EPAS1 protein affects the susceptibility to sodium arsenite CTD PMID:23333640 sodium cyanide multiple interactions EXP 6480464 Sodium Cyanide inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:18353899 sunitinib decreases expression ISO RGD:68594 6480464 Sunitinib results in decreased expression of EPAS1 mRNA CTD PMID:31533062 T-2 Toxin multiple interactions ISO RGD:68595 6480464 BAY 11-7085 inhibits the reaction [T-2 Toxin results in increased expression of EPAS1 mRNA], BAY 11-7085 inhibits the reaction [T-2 Toxin results in increased expression of EPAS1 protein] CTD PMID:22800716 T-2 Toxin increases expression ISO RGD:68595 6480464 T-2 Toxin results in increased expression of EPAS1 mRNA, T-2 Toxin results in increased expression of EPAS1 protein CTD PMID:22800716 thapsigargin decreases expression ISO RGD:68594 6480464 Thapsigargin results in decreased expression of EPAS1 mRNA CTD PMID:22378314 trichloroethene decreases expression ISO RGD:68595 6480464 Trichloroethylene results in decreased expression of EPAS1 mRNA CTD PMID:19448997 trichloroethene increases expression ISO RGD:68595 6480464 Trichloroethylene results in increased expression of EPAS1 mRNA CTD PMID:15363585 trichostatin A increases expression ISO RGD:68594 6480464 trichostatin A results in increased expression of EPAS1 mRNA CTD PMID:24935251 more ... trichostatin A multiple interactions ISO RGD:68594 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPAS1 mRNA CTD PMID:27188386 troglitazone decreases expression ISO RGD:68595 6480464 troglitazone results in decreased expression of EPAS1 mRNA CTD PMID:28973697 tunicamycin decreases expression ISO RGD:68594 6480464 Tunicamycin results in decreased expression of EPAS1 mRNA CTD PMID:22378314 valproic acid multiple interactions ISO RGD:68594 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of EPAS1 mRNA more ... CTD PMID:17183730 , PMID:27188386 valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of EPAS1 mRNA CTD PMID:29427782 valproic acid increases expression ISO RGD:68594 6480464 Valproic Acid results in increased expression of EPAS1 mRNA CTD PMID:23179753 more ... valproic acid affects expression ISO RGD:68595 6480464 Valproic Acid affects the expression of EPAS1 mRNA CTD PMID:17292431 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of EPAS1 mRNA CTD PMID:19015723 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of EPAS1 mRNA CTD PMID:30207508 vorinostat decreases expression ISO RGD:68594 6480464 vorinostat results in decreased expression of EPAS1 mRNA CTD PMID:18769122 zearalenone increases expression ISO RGD:68595 6480464 Zearalenone results in increased expression of EPAS1 mRNA CTD PMID:30138655
Biological Process angiogenesis ISO RGD:68595 1624291 MGI:MGI:1861921 more ... RGD MGI:MGI:2181852 more ... angiogenesis IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 blood vessel remodeling ISO RGD:68595 1624291 MGI:MGI:2386334 (MGI:MGI:1860986 , PMID:10880563) RGD MGI:MGI:1860986 , PMID:10880563 blood vessel remodeling IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 cell differentiation ISO RGD:68595 1624291 MGI:MGI:106918 (MGI:MGI:3703383 , PMID:16287860) RGD MGI:MGI:3703383 , PMID:16287860 cell maturation ISO RGD:68595 1624291 MGI:MGI:2663583 (MGI:MGI:2181852 , PMID:12053176) RGD MGI:MGI:2181852 , PMID:12053176 cell maturation IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 cellular response to hypoxia IEP 11041576 RGD cellular response to hypoxia ISS UniProtKB:Q99814 1600115 GO_REF:0000024 UniProt GO_REF:0000024 cellular response to hypoxia IEA UniProtKB:Q99814 , ensembl:ENSP000002637341600115 GO_REF:0000107 Ensembl GO_REF:0000107 cellular response to hypoxia ISO RGD:68594 1624291 (PMID:11573933) RGD PMID:11573933 cellular response to interleukin-1 IEP 11041576 RGD cellular response to lipopolysaccharide IEP 11041576 RGD embryonic placenta development ISO RGD:68595 1624291 MGI:MGI:106918 (MGI:MGI:3703383 , PMID:16287860) RGD MGI:MGI:3703383 , PMID:16287860 embryonic placenta development IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 erythrocyte differentiation ISO RGD:68595 1624291 MGI:MGI:3710344 (MGI:MGI:3703197 , PMID:17284606) RGD MGI:MGI:3703197 , PMID:17284606 erythrocyte differentiation IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 hemopoiesis ISO RGD:68595 1624291 MGI:MGI:1861921 (MGI:MGI:2673768 more ... RGD MGI:MGI:2673768 more ... iron ion homeostasis ISO RGD:68595 1624291 MGI:MGI:109169 (MGI:MGI:5314161 , PMID:22128145) RGD MGI:MGI:5314161 , PMID:22128145 iron ion homeostasis IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 lung development ISO RGD:68595 1624291 MGI:MGI:2663583 (MGI:MGI:2181852 , PMID:12053176) RGD MGI:MGI:2181852 , PMID:12053176 lung development IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 mitochondrion organization ISO RGD:68595 1624291 MGI:MGI:1861921 (MGI:MGI:2681387 , PMID:14608355) RGD MGI:MGI:2681387 , PMID:14608355 mitochondrion organization IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 myoblast fate commitment ISO RGD:68595 1624291 (MGI:MGI:4867337, PMID:21106753) RGD MGI:MGI:4867337 , PMID:21106753 myoblast fate commitment IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of transcription by RNA polymerase II IMP 5147880 RGD norepinephrine biosynthetic process IMP 5128877 RGD norepinephrine metabolic process ISO RGD:68595 1624291 MGI:MGI:1861921 (MGI:MGI:1313089 , PMID:9808618) RGD MGI:MGI:1313089 , PMID:9808618 norepinephrine metabolic process IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of cold-induced thermogenesis ISS UniProtKB:P97481 11251638 PMID:26572826 YuBioLab positive regulation of cold-induced thermogenesis ISO RGD:68595 1624291 (MGI:MGI:5803933, PMID:26572826) RGD MGI:MGI:5803933 , PMID:26572826 positive regulation of dopamine biosynthetic process IMP 5128877 RGD positive regulation of lung alveolus development IEP 10395379 RGD positive regulation of transcription by RNA polymerase II IDA 68201 RGD positive regulation of transcription by RNA polymerase II IBA FB:FBgn0039411 more ... 13792537 PMID:21873635 GO_Central positive regulation of transcription by RNA polymerase II IEA UniProtKB:Q99814 , ensembl:ENSP000002637341600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of transcription by RNA polymerase II IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of transcription by RNA polymerase II ISO RGD:68594 1624291 UniProtKB:O00327 , UniProtKB:P53762 (PMID:11573933), (PMID:9000051), (PMID:9576906) RGD PMID:11573933 more ... positive regulation of transcription by RNA polymerase II ISO RGD:68595 1624291 MGI:MGI:3526731 more ... RGD MGI:MGI:2451217 more ... regulation of heart rate ISO RGD:68595 1624291 MGI:MGI:1861921 (MGI:MGI:1313089 , PMID:9808618) RGD MGI:MGI:1313089 , PMID:9808618 regulation of heart rate IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of transcription by RNA polymerase II IBA FB:FBgn0004666 more ... 13792537 PMID:21873635 GO_Central regulation of transcription from RNA polymerase II promoter in response to oxidative stress NOT ISO RGD:68595 1624291 MGI:MGI:106918 (MGI:MGI:2667513 , PMID:12832481) RGD MGI:MGI:2667513 , PMID:12832481 regulation of transcription from RNA polymerase II promoter in response to oxidative stress IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of transcription from RNA polymerase II promoter in response to oxidative stress ISO RGD:68595 1624291 MGI:MGI:3710344 (MGI:MGI:2681387 more ... RGD MGI:MGI:2681387 more ... regulation of transcription, DNA-templated IEA InterPro:IPR001067 1600115 GO_REF:0000002 InterPro GO_REF:0000002 response to hypoxia IDA 632652 RGD response to hypoxia ISO RGD:68594 1624291 (PMID:11782478) RGD PMID:11782478 response to hypoxia ISO RGD:68595 1624291 MGI:MGI:1861921 (MGI:MGI:3578492 , PMID:15626745) RGD MGI:MGI:3578492 , PMID:15626745 response to oxidative stress ISO RGD:68595 1624291 MGI:MGI:1861921 more ... RGD MGI:MGI:2681387 more ... surfactant homeostasis ISO RGD:68595 1624291 MGI:MGI:2663583 (MGI:MGI:2181852 , PMID:12053176) RGD MGI:MGI:2181852 , PMID:12053176 surfactant homeostasis IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 visual perception ISO RGD:68595 1624291 MGI:MGI:1861921 (MGI:MGI:3530393 , PMID:15728559) RGD MGI:MGI:3530393 , PMID:15728559 visual perception IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 Cellular Component cytoplasm IDA 1581932 RGD cytoplasm IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 cytoplasm IEA InterPro:IPR001067 1600115 GO_REF:0000002 InterPro GO_REF:0000002 cytoplasm ISO RGD:68595 1624291 (MGI:MGI:2667513, PMID:12832481) RGD MGI:MGI:2667513 , PMID:12832481 nuclear speck ISO RGD:68595 1624291 (MGI:MGI:5526927, PMID:21546903) RGD MGI:MGI:5526927 , PMID:21546903 nuclear speck IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 nucleus IDA 1581932 RGD nucleus IBA FB:FBgn0004666 more ... 13792537 PMID:21873635 GO_Central nucleus IEA UniProtKB-SubCell:SL-0191 1600115 GO_REF:0000044 UniProt GO_REF:0000044 nucleus ISO RGD:68595 1624291 (MGI:MGI:2451217 more ... RGD MGI:MGI:2451217 more ... transcription regulator complex ISO RGD:68595 1624291 (MGI:MGI:2451217, PMID:12464608) RGD MGI:MGI:2451217 , PMID:12464608 transcription regulator complex IEA UniProtKB:Q99814 , ensembl:ENSP000002637341600115 GO_REF:0000107 Ensembl GO_REF:0000107 transcription regulator complex IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 transcription regulator complex ISO RGD:68594 1624291 UniProtKB:O00327 (PMID:9000051), (PMID:9576906) RGD PMID:9000051 , PMID:9576906 transcription regulator complex IEA InterPro:IPR001067 1600115 GO_REF:0000002 InterPro GO_REF:0000002 Molecular Function cis-regulatory region sequence-specific DNA binding ISO RGD:68595 1624291 (MGI:MGI:2451217, PMID:12464608) RGD MGI:MGI:2451217 , PMID:12464608 cobalt ion binding IDA 10395380 RGD DNA binding ISO RGD:68594 1624291 UniProtKB:P53762 (PMID:9000051) RGD PMID:9000051 DNA binding ISO RGD:68595 1624291 (MGI:MGI:3709688, PMID:17404621) RGD MGI:MGI:3709688 , PMID:17404621 DNA-binding transcription activator activity, RNA polymerase II-specific ISO RGD:68595 1624291 (MGI:MGI:5306879, PMID:21856340) RGD MGI:MGI:5306879 , PMID:21856340 DNA-binding transcription activator activity, RNA polymerase II-specific IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 DNA-binding transcription factor activity IDA 68201 RGD DNA-binding transcription factor activity IEA InterPro:IPR001067 1600115 GO_REF:0000002 InterPro GO_REF:0000002 DNA-binding transcription factor activity ISO RGD:68595 1624291 (MGI:MGI:2451217, PMID:12464608) RGD MGI:MGI:2451217 , PMID:12464608 DNA-binding transcription factor activity, RNA polymerase II-specific IBA FB:FBgn0004666 more ... 13792537 PMID:21873635 GO_Central histone acetyltransferase binding ISO RGD:68594 1624291 UniProtKB:Q09472 (PMID:15261140) RGD PMID:15261140 histone acetyltransferase binding IEA UniProtKB:Q99814 , ensembl:ENSP000002637341600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein binding ISO RGD:68594 1624291 UniProtKB:A0A024R8A9 more ... RGD PMID:11018023 more ... protein binding ISO RGD:68595 1624291 PR:P53762 more ... RGD MGI:MGI:5526927 more ... protein dimerization activity IEA InterPro:IPR011598 , InterPro:IPR036638 1600115 GO_REF:0000002 InterPro GO_REF:0000002 protein heterodimerization activity IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein heterodimerization activity ISO RGD:68595 1624291 (MGI:MGI:5927132, PMID:26245371) RGD MGI:MGI:5927132 , PMID:26245371 protein heterodimerization activity ISO RGD:68594 1624291 UniProtKB:P27540 (PMID:16181639), (PMID:9079689) RGD PMID:16181639 , PMID:9079689 protein heterodimerization activity ISS UniProtKB:Q99814 1600115 GO_REF:0000024 UniProt GO_REF:0000024 protein heterodimerization activity ISS UniProtKB:P97481 1600115 GO_REF:0000024 UniProt GO_REF:0000024 protein heterodimerization activity IEA UniProtKB:Q99814 , ensembl:ENSP000002637341600115 GO_REF:0000107 Ensembl GO_REF:0000107 RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 RNA polymerase II cis-regulatory region sequence-specific DNA binding ISO RGD:68595 1624291 MGI:MGI:88071 (MGI:MGI:894004 , PMID:9113979) RGD MGI:MGI:894004 , PMID:9113979 sequence-specific DNA binding contributes_to IDA 632652 RGD sequence-specific DNA binding ISO RGD:68595 1624291 (MGI:MGI:5927132, PMID:26245371) RGD MGI:MGI:5927132 , PMID:26245371 sequence-specific DNA binding contributes_to ISO RGD:68594 1624291 (PMID:9079689) RGD PMID:9079689 transcription factor binding ISO RGD:68595 1624291 PR:P27577 (MGI:MGI:2451217, PMID:12464608) RGD MGI:MGI:2451217 , PMID:12464608 transcription factor binding IEA UniProtKB:Q99814 , ensembl:ENSP000002637341600115 GO_REF:0000107 Ensembl GO_REF:0000107 transcription factor binding IEA UniProtKB:P97481 , ensembl:ENSMUSP000000249541600115 GO_REF:0000107 Ensembl GO_REF:0000107 transcription factor binding ISO RGD:68594 1624291 UniProtKB:P27540 (PMID:9079689) RGD PMID:9079689
Gene-Chemical Interaction Annotations
