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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-catechin | multiple interactions | ISO | RGD:1346114 | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of SLC30A3 mRNA | CTD | PMID:24763279 | 1,2-dichloroethane | increases expression | ISO | RGD:1552396 | 6480464 | ethylene dichloride results in increased expression of SLC30A3 mRNA | CTD | PMID:28960355 | 1-naphthyl isothiocyanate | decreases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of SLC30A3 mRNA | CTD | PMID:30723492 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:1552396 | 6480464 | Ethinyl Estradiol results in increased expression of SLC30A3 mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of SLC30A3 mRNA | CTD | PMID:29097150 | 17beta-estradiol | decreases expression | ISO | RGD:1552396 | 6480464 | Estradiol results in decreased expression of SLC30A3 protein | CTD | PMID:14681234 | 17beta-estradiol | multiple interactions | ISO | RGD:1552396 | 6480464 | SLC30A3 gene mutant form inhibits the reaction [Estradiol results in decreased abundance of Zinc] | CTD | PMID:14681234 | 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one | increases expression | ISO | RGD:1346114 | 6480464 | Metribolone results in increased expression of SLC30A3 mRNA | CTD | PMID:14662799 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1552396 | 6480464 | Tetrachlorodibenzodioxin affects the expression of SLC30A3 mRNA | CTD | PMID:24680724 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SLC30A3 mRNA | CTD | PMID:32109520 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | RGD:1552396 | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of SLC30A3 mRNA | CTD | PMID:20188158 | 4-hydroxyphenyl retinamide | increases expression | ISO | RGD:1552396 | 6480464 | Fenretinide results in increased expression of SLC30A3 mRNA | CTD | PMID:28973697 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of SLC30A3 mRNA | CTD | PMID:28959563 | aldehydo-D-glucose | increases expression | ISO | RGD:1552396 | 6480464 | Glucose results in increased expression of SLC30A3 | CTD | PMID:19492079 | aldehydo-D-glucose | affects expression | EXP | | 6480464 | Glucose affects the expression of SLC30A3 | CTD | PMID:19492079 | aldehydo-D-glucose | multiple interactions | EXP | | 6480464 | [Glucose co-treated with dihydroxyethyldithiocarbamate] results in increased expression of SLC30A3 mRNA | CTD | PMID:19492079 | aldehydo-D-glucose | multiple interactions | ISO | RGD:1552396 | 6480464 | SLC30A3 results in increased susceptibility to [Glucose co-treated with INS1 protein] | CTD | PMID:18545258 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of SLC30A3 mRNA | CTD | PMID:16483693 | arsane | affects methylation | ISO | RGD:1346114 | 6480464 | Arsenic affects the methylation of SLC30A3 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | RGD:1346114 | 6480464 | Arsenic affects the methylation of SLC30A3 gene | CTD | PMID:25304211 | atrazine | increases expression | ISO | RGD:1346114 | 6480464 | Atrazine results in increased expression of SLC30A3 mRNA | CTD | PMID:22378314 | bafilomycin A1 | multiple interactions | EXP | | 6480464 | bafilomycin A1 inhibits the reaction [SLC30A3 protein promotes the reaction [SLC17A7 protein results in increased uptake of Zinc]] | CTD | PMID:15860731 | benzo[a]pyrene | decreases expression | ISO | RGD:1552396 | 6480464 | Benzo(a)pyrene results in decreased expression of SLC30A3 mRNA | CTD | PMID:32417428 | benzo[a]pyrene | increases methylation | ISO | RGD:1346114 | 6480464 | Benzo(a)pyrene results in increased methylation of SLC30A3 3' UTR, Benzo(a)pyrene results in increased methylation of SLC30A3 promoter | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | RGD:1346114 | 6480464 | Diethylhexyl Phthalate results in decreased expression of SLC30A3 mRNA | CTD | PMID:31163220 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of SLC30A3 gene | CTD | PMID:28505145 | bisphenol A | increases expression | ISO | RGD:1552396 | 6480464 | bisphenol A results in increased expression of SLC30A3 mRNA | CTD | PMID:32365465 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SLC30A3 mRNA | CTD | PMID:30816183, PMID:34947998 | butanal | increases expression | ISO | RGD:1346114 | 6480464 | butyraldehyde results in increased expression of SLC30A3 mRNA | CTD | PMID:26079696 | cadmium dichloride | affects expression | EXP | | 6480464 | Cadmium Chloride affects the expression of SLC30A3 mRNA | CTD | PMID:29548726 | carmustine | decreases expression | ISO | RGD:1346114 | 6480464 | Carmustine results in decreased expression of SLC30A3 mRNA | CTD | PMID:15980968 | CGP 52608 | multiple interactions | ISO | RGD:1346114 | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SLC30A3 gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of SLC30A3 mRNA | CTD | PMID:20691718 | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of SLC30A3 mRNA | CTD | PMID:22023808 | cisplatin | decreases expression | ISO | RGD:1346114 | 6480464 | Cisplatin results in decreased expression of SLC30A3 mRNA | CTD | PMID:27392435 | cisplatin | increases expression | ISO | RGD:1346114 | 6480464 | Cisplatin results in increased expression of SLC30A3 mRNA | CTD | PMID:19561079 | clofibrate | decreases expression | ISO | RGD:1552396 | 6480464 | Clofibrate results in decreased expression of SLC30A3 mRNA | CTD | PMID:17585979 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of SLC30A3 mRNA | CTD | PMID:26577399 | D-glucose | multiple interactions | ISO | RGD:1552396 | 6480464 | SLC30A3 results in increased susceptibility to [Glucose co-treated with INS1 protein] | CTD | PMID:18545258 | D-glucose | multiple interactions | EXP | | 6480464 | [Glucose co-treated with dihydroxyethyldithiocarbamate] results in increased expression of SLC30A3 mRNA | CTD | PMID:19492079 | D-glucose | affects expression | EXP | | 6480464 | Glucose affects the expression of SLC30A3 | CTD | PMID:19492079 | D-glucose | increases expression | ISO | RGD:1552396 | 6480464 | Glucose results in increased expression of SLC30A3 | CTD | PMID:19492079 | dichloroacetic acid | decreases expression | ISO | RGD:1552396 | 6480464 | Dichloroacetic Acid results in decreased expression of SLC30A3 mRNA | CTD | PMID:28962523 | disodium selenite | decreases expression | ISO | RGD:1346114 | 6480464 | Sodium Selenite results in decreased expression of SLC30A3 mRNA | CTD | PMID:18175754 | ethanol | decreases expression | EXP | | 6480464 | Ethanol results in decreased expression of SLC30A3 mRNA | CTD | PMID:20655511 | ethanol | affects expression | ISO | RGD:1552396 | 6480464 | Ethanol affects the expression of SLC30A3 mRNA | CTD | PMID:30319688 | ethanol | affects splicing | ISO | RGD:1552396 | 6480464 | Ethanol affects the splicing of SLC30A3 mRNA | CTD | PMID:30319688 | ethanol | multiple interactions | EXP | | 6480464 | N-methyl-N-(6-methoxy-1-phenyl-1 more ... | CTD | PMID:20655511 | fluoxetine | decreases expression | EXP | | 6480464 | Fluoxetine results in decreased expression of SLC30A3 mRNA | CTD | PMID:17033635 | flurotyl | affects expression | EXP | | 6480464 | Flurothyl affects the expression of SLC30A3 mRNA | CTD | PMID:20167268 | folic acid | decreases expression | ISO | RGD:1346114 | 6480464 | Folic Acid results in decreased expression of SLC30A3 mRNA | CTD | PMID:21867686 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of SLC30A3 mRNA | CTD | PMID:33387578 | glucose | multiple interactions | ISO | RGD:1552396 | 6480464 | SLC30A3 results in increased susceptibility to [Glucose co-treated with INS1 protein] | CTD | PMID:18545258 | glucose | multiple interactions | EXP | | 6480464 | [Glucose co-treated with dihydroxyethyldithiocarbamate] results in increased expression of SLC30A3 mRNA | CTD | PMID:19492079 | glucose | affects expression | EXP | | 6480464 | Glucose affects the expression of SLC30A3 | CTD | PMID:19492079 | glucose | increases expression | ISO | RGD:1552396 | 6480464 | Glucose results in increased expression of SLC30A3 | CTD | PMID:19492079 | lead(0) | affects expression | ISO | RGD:1346114 | 6480464 | Lead affects the expression of SLC30A3 mRNA | CTD | PMID:28903495 | lead(2+) | affects expression | ISO | RGD:1346114 | 6480464 | Lead affects the expression of SLC30A3 mRNA | CTD | PMID:28903495 | ozone | increases expression | EXP | | 6480464 | Ozone results in increased expression of SLC30A3 mRNA | CTD | PMID:28623178 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of SLC30A3 mRNA | CTD | PMID:30723492 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SLC30A3 mRNA | CTD | PMID:33387578 | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of SLC30A3 mRNA | CTD | PMID:32680482 | pentanal | increases expression | ISO | RGD:1346114 | 6480464 | pentanal results in increased expression of SLC30A3 mRNA | CTD | PMID:26079696 | propanal | increases expression | ISO | RGD:1346114 | 6480464 | propionaldehyde results in increased expression of SLC30A3 mRNA | CTD | PMID:26079696 | reactive oxygen species | decreases abundance | EXP | | 6480464 | SLC30A3 protein results in decreased abundance of Reactive Oxygen Species | CTD | PMID:22427991 | reactive oxygen species | multiple interactions | EXP | | 6480464 | [SLC30A3 protein affects the expression of CAT protein] which affects the abundance of Reactive Oxygen Species | CTD | PMID:22427991 | silicon dioxide | decreases expression | ISO | RGD:1346114 | 6480464 | Silicon Dioxide analog results in decreased expression of SLC30A3 mRNA | CTD | PMID:25895662 | sunitinib | decreases expression | ISO | RGD:1346114 | 6480464 | Sunitinib results in decreased expression of SLC30A3 mRNA | CTD | PMID:31533062 | temozolomide | increases expression | ISO | RGD:1346114 | 6480464 | Temozolomide results in increased expression of SLC30A3 mRNA | CTD | PMID:31758290 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of SLC30A3 mRNA | CTD | PMID:34492290 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of SLC30A3 mRNA | CTD | PMID:33387578 | triphenyl phosphate | decreases expression | EXP | | 6480464 | triphenyl phosphate results in decreased expression of SLC30A3 mRNA | CTD | PMID:30589522 | triptonide | increases expression | ISO | RGD:1552396 | 6480464 | triptonide results in increased expression of SLC30A3 mRNA | CTD | PMID:33045310 | valproic acid | increases expression | ISO | RGD:1346114 | 6480464 | Valproic Acid results in increased expression of SLC30A3 mRNA | CTD | PMID:29154799 | valproic acid | affects expression | ISO | RGD:1346114 | 6480464 | Valproic Acid affects the expression of SLC30A3 mRNA | CTD | PMID:25979313 | vanadium atom | decreases expression | ISO | RGD:1346114 | 6480464 | Vanadium results in decreased expression of SLC30A3 mRNA | CTD | PMID:19000753 | vanadium(0) | decreases expression | ISO | RGD:1346114 | 6480464 | Vanadium results in decreased expression of SLC30A3 mRNA | CTD | PMID:19000753 | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of SLC30A3 mRNA | CTD | PMID:23034163 | zidovudine | increases expression | ISO | RGD:1346114 | 6480464 | Zidovudine results in increased expression of SLC30A3 mRNA | CTD | PMID:24292225 | zinc atom | increases transport | ISO | RGD:1346114 | 6480464 | SLC30A3 protein results in increased transport of Zinc | CTD | PMID:18326752 | zinc atom | multiple interactions | ISO | RGD:1552396 | 6480464 | SLC30A3 gene mutant form inhibits the reaction [Estradiol results in decreased abundance of Zinc] | CTD | PMID:14681234 | zinc atom | affects secretion | ISO | RGD:1552396 | 6480464 | SLC30A3 protein affects the secretion of Zinc | CTD | PMID:17949919 | zinc atom | decreases expression | EXP | | 6480464 | Zinc results in decreased expression of SLC30A3 mRNA | CTD | PMID:22427991 | zinc atom | decreases expression | ISO | RGD:1346114 | 6480464 | Zinc results in decreased expression of SLC30A3 mRNA | CTD | PMID:19071009 | zinc atom | affects abundance | EXP | | 6480464 | SLC30A3 protein affects the abundance of Zinc | CTD | PMID:22427991 | zinc atom | increases abundance | ISO | RGD:1346114 | 6480464 | SLC30A3 protein results in increased abundance of Zinc | CTD | PMID:17349999 | zinc atom | increases transport | EXP | | 6480464 | SLC30A3 protein results in increased transport of Zinc | CTD | PMID:15883362 | zinc atom | multiple interactions | EXP | | 6480464 | [Fatty Acids more ... | CTD | PMID:15860731 more ... | zinc(0) | increases transport | ISO | RGD:1346114 | 6480464 | SLC30A3 protein results in increased transport of Zinc | CTD | PMID:18326752 | zinc(0) | multiple interactions | EXP | | 6480464 | [Fatty Acids more ... | CTD | PMID:15860731 more ... | zinc(0) | increases transport | EXP | | 6480464 | SLC30A3 protein results in increased transport of Zinc | CTD | PMID:15883362 | zinc(0) | increases abundance | ISO | RGD:1346114 | 6480464 | SLC30A3 protein results in increased abundance of Zinc | CTD | PMID:17349999 | zinc(0) | affects abundance | EXP | | 6480464 | SLC30A3 protein affects the abundance of Zinc | CTD | PMID:22427991 | zinc(0) | decreases expression | ISO | RGD:1346114 | 6480464 | Zinc results in decreased expression of SLC30A3 mRNA | CTD | PMID:19071009 | zinc(0) | decreases expression | EXP | | 6480464 | Zinc results in decreased expression of SLC30A3 mRNA | CTD | PMID:22427991 | zinc(0) | affects secretion | ISO | RGD:1552396 | 6480464 | SLC30A3 protein affects the secretion of Zinc | CTD | PMID:17949919 | zinc(0) | multiple interactions | ISO | RGD:1552396 | 6480464 | SLC30A3 gene mutant form inhibits the reaction [Estradiol results in decreased abundance of Zinc] | CTD | PMID:14681234 | |