Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dpysl5 | Rat | Ritscher-Schinzel Syndrome 4 | | ISO | DPYSL5 (Homo sapiens) | 7240710 | | OMIM | | |
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Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dpysl5 | Rat | Ritscher-Schinzel Syndrome 4 | | ISO | DPYSL5 (Homo sapiens) | 7240710 | | OMIM | | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
3. | Ulip6, a novel unc-33 and dihydropyrimidinase related protein highly expressed in developing rat brain. | Horiuchi M, etal., FEBS Lett 2000 Sep 1;480(2-3):283-6. |
4. | Identification of CRAM, a novel unc-33 gene family protein that associates with CRMP3 and protein-tyrosine kinase(s) in the developing rat brain. | Inatome R, etal., J Biol Chem 2000 Sep 1;275(35):27291-302. |
5. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
6. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
7. | GOA pipeline | RGD automated data pipeline |
8. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
PMID:11069615 | PMID:15834957 | PMID:19805073 | PMID:22871113 | PMID:26677106 |
Dpysl5 (Rattus norvegicus - Norway rat) |
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DPYSL5 (Homo sapiens - human) |
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Dpysl5 (Mus musculus - house mouse) |
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Dpysl5 (Chinchilla lanigera - long-tailed chinchilla) |
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DPYSL5 (Pan paniscus - bonobo/pygmy chimpanzee) |
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DPYSL5 (Canis lupus familiaris - dog) |
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Dpysl5 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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DPYSL5 (Sus scrofa - pig) |
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DPYSL5 (Chlorocebus sabaeus - green monkey) |
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Dpysl5 (Heterocephalus glaber - naked mole-rat) |
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Variants in Dpysl5
508 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
IB426 |
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RH131974 |
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UniSTS:478904 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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nervous system
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renal system
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reproductive system
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respiratory system
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9 | 11 | 44 | 113 | 89 | 88 | 59 | 23 | 59 | 6 | 210 | 90 | 93 | 44 | 60 | 29 |
Ensembl Acc Id: | ENSRNOT00000012273 ⟹ ENSRNOP00000012274 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NM_023023 ⟹ NP_075412 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
Protein RefSeqs | NP_075412 | (Get FASTA) | NCBI Sequence Viewer |
GenBank Protein | BAA89475 | (Get FASTA) | NCBI Sequence Viewer |
CAB95193 | (Get FASTA) | NCBI Sequence Viewer | |
EDM02977 | (Get FASTA) | NCBI Sequence Viewer | |
EDM02978 | (Get FASTA) | NCBI Sequence Viewer | |
EDM02979 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000012274.4 | ||
ENSRNOP00055028010 | |||
ENSRNOP00060015588 | |||
ENSRNOP00065033328 | |||
GenBank Protein | Q9JHU0 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_075412 ⟸ NM_023023 |
- UniProtKB: | Q9JHU0 (UniProtKB/Swiss-Prot), A6HAC3 (UniProtKB/TrEMBL), Q9JMG8 (UniProtKB/TrEMBL) |
- Sequence: |
Ensembl Acc Id: | ENSRNOP00000012274 ⟸ ENSRNOT00000012273 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q9JHU0-F1-model_v2 | AlphaFold | Q9JHU0 | 1-564 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13694461 | ||||||||
Promoter ID: | EPDNEW_R4984 | ||||||||
Type: | single initiation site | ||||||||
Name: | Dpysl5_1 | ||||||||
Description: | dihydropyrimidinase-like 5 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:620467 | AgrOrtholog |
BioCyc Gene | G2FUF-38320 | BioCyc |
BioCyc Pathway | PWY-3982 [uracil degradation I (reductive)] | BioCyc |
PWY-6430 [thymine degradation] | BioCyc | |
BioCyc Pathway Image | PWY-3982 | BioCyc |
PWY-6430 | BioCyc | |
Ensembl Genes | ENSRNOG00000008996 | Ensembl, UniProtKB/Swiss-Prot |
ENSRNOG00055020241 | UniProtKB/Swiss-Prot | |
ENSRNOG00060011734 | UniProtKB/Swiss-Prot | |
ENSRNOG00065023820 | UniProtKB/Swiss-Prot | |
Ensembl Transcript | ENSRNOT00000012273.5 | UniProtKB/Swiss-Prot |
ENSRNOT00055034570 | UniProtKB/Swiss-Prot | |
ENSRNOT00060019851 | UniProtKB/Swiss-Prot | |
ENSRNOT00065040842 | UniProtKB/Swiss-Prot | |
Gene3D-CATH | 2.30.40.10 | UniProtKB/Swiss-Prot |
Metal-dependent hydrolases | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Urease, subunit C, domain 1 | UniProtKB/TrEMBL | |
InterPro | Amidohydro-rel | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Hydantoinase/dihydroPyrase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Metal-dep_hydrolase_composite | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Metal_Hydrolase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Metallo-dep_Hydrolases_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:65208 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
NCBI Gene | 65208 | ENTREZGENE |
PANTHER | DIHYDROPYRIMIDINASE-RELATED PROTEIN 5 | UniProtKB/TrEMBL |
HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PTHR11647:SF58 | UniProtKB/Swiss-Prot | |
Pfam | Amidohydro_1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PhenoGen | Dpysl5 | PhenoGen |
RatGTEx | ENSRNOG00000008996 | RatGTEx |
ENSRNOG00055020241 | RatGTEx | |
ENSRNOG00060011734 | RatGTEx | |
ENSRNOG00065023820 | RatGTEx | |
Superfamily-SCOP | Composite domain of metallo-dependent hydrolases | UniProtKB/TrEMBL |
Metallo-dependent hydrolases | UniProtKB/TrEMBL | |
SSF51338 | UniProtKB/Swiss-Prot | |
SSF51556 | UniProtKB/Swiss-Prot | |
UniProt | A6HAC2_RAT | UniProtKB/TrEMBL |
A6HAC3 | ENTREZGENE, UniProtKB/TrEMBL | |
A6HAC4_RAT | UniProtKB/TrEMBL | |
DPYL5_RAT | UniProtKB/Swiss-Prot, ENTREZGENE | |
Q9JMG8 | ENTREZGENE, UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2021-03-09 | Dpysl5 | dihydropyrimidinase-like 5 | LOC100911610 | dihydropyrimidinase-related protein 5-like | Data merged from RGD:6492163 | 737654 | PROVISIONAL |
2012-07-05 | LOC100911610 | dihydropyrimidinase-related protein 5-like | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
2004-09-10 | Dpysl5 | dihydropyrimidinase-like 5 | Crmp5 | dihydropyrimidinase-related protein | Symbol and Name updated | 1299863 | APPROVED |
2002-08-07 | Crmp5 | dihydropyrimidinase-related protein | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
Note Type | Note | Reference |
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gene_expression | highly expressed in embryonic and early postnatal brain and spinal cord | 632608 |
gene_function | associated with CRMP3 | 632609 |
gene_regulation | expression is up-regulated during neuronal differentiation | 632609 |