Kif3c (kinesin family member 3C) - Rat Genome Database

Name: Kif3c
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Kif3c (kinesin family member 3C) Rattus norvegicus

Analyze

Symbol:

Kif3c

Name:

kinesin family member 3C

RGD ID:

621538

Description:

Exhibits kinesin binding activity and microtubule binding activity. Involved in positive regulation of neuron projection development. Localizes to several cellular components, including microtubule plus-end; neuronal ribonucleoprotein granule; and synaptic vesicle. Colocalizes with microtubule. Orthologous to human KIF3C (kinesin family member 3C); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

kinesin-like protein KIF3C

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KIF3C (kinesin family member 3C)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Kif3c (kinesin family member 3C)	HGNC	Treefam, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Kif3c (kinesin family member 3C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	KIF3C (kinesin family member 3C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KIF3C (kinesin family member 3C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Kif3c (kinesin family member 3C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KIF3C (kinesin family member 3C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	KIF3C (kinesin family member 3C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Kif3c (kinesin family member 3C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	KIF3C (kinesin family member 3C)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Mus musculus (house mouse):	Kif3c (kinesin family member 3C)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	kif3cb (kinesin family member 3Cb)	Alliance	DIOPT (Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|TreeFam)
Drosophila melanogaster (fruit fly):	Klp68D	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|PANTHER\|PhylomeDB\|TreeFam)
Caenorhabditis elegans (roundworm):	klp-11	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	6	27,768,943 - 27,815,611 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	27,768,943 - 27,815,611 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	37,579,445 - 37,625,883 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	26,342,388 - 26,381,233 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	6	26,345,340 - 26,384,186 (+)	NCBI
Celera	6	25,843,783 - 25,882,712 (+)	NCBI		Celera
Cytogenetic Map	6	q14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amyotrophic lateral sclerosis type 1 (ISO)

atrial fibrillation (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methylcholine (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

aflatoxin B2 (ISO)

ammonium chloride (EXP)

amphetamine (EXP)

benzo[a]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP)

cadmium dichloride (EXP)

calcitriol (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

D-gluconic acid (EXP)

dibutyl phthalate (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

ethanol (ISO)

hypochlorous acid (ISO)

lead(0) (ISO)

lead(2+) (ISO)

paracetamol (ISO)

pirinixic acid (EXP,ISO)

propanal (ISO)

raloxifene (ISO)

SB 431542 (ISO)

succimer (ISO)

tamoxifen (ISO)

testosterone (ISO)

thioacetamide (EXP)

trichostatin A (ISO)

tungsten (ISO)

tunicamycin (ISO)

uranium atom (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

microtubule-based movement (IBA)

organelle transport along microtubule (IEA,ISO)

positive regulation of neuron projection development (IMP)

Cellular Component

axon (IDA)

dendrite (IDA)

growth cone (IDA)

kinesin complex (IBA)

membrane (IDA)

microtubule (IEA)

microtubule cytoskeleton (IDA)

microtubule plus-end (IDA)

neuronal cell body (IDA)

neuronal ribonucleoprotein granule (IDA)

synaptic vesicle (IDA)

Molecular Function

ATP binding (IEA)

ATPase activity (IBA)

kinesin binding (IPI)

microtubule binding (IBA,IDA,IEA)

microtubule motor activity (IBA,IEA)

protein binding (ISO)

References

References - curated


1.	Davidovic L, etal., Hum Mol Genet. 2007 Dec 15;16(24):3047-58. Epub 2007 Sep 19.
2.	Faire K, etal., Eur J Cell Biol 1998 Sep;77(1):27-34.
3.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	GOA data from the GO Consortium
5.	Gumy LF, etal., J Neurosci. 2013 Jul 10;33(28):11329-45. doi: 10.1523/JNEUROSCI.5221-12.2013.
6.	Muresan V, etal., Mol Biol Cell 1998 Mar;9(3):637-52.
7.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	RGD automated data pipeline
9.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Kif3c
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	6	27,768,943 - 27,815,611 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	27,768,943 - 27,815,611 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	37,579,445 - 37,625,883 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	26,342,388 - 26,381,233 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	6	26,345,340 - 26,384,186 (+)	NCBI
Celera	6	25,843,783 - 25,882,712 (+)	NCBI		Celera
Cytogenetic Map	6	q14	NCBI

KIF3C
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	2	25,926,598 - 25,982,749 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	2	25,926,598 - 25,982,740 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	2	26,149,455 - 26,205,443 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	26,002,959 - 26,058,947 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	2	26,061,118 - 26,117,054	NCBI
Celera	2	25,989,739 - 26,045,730 (-)	NCBI
Cytogenetic Map	2	p23.3	NCBI
HuRef	2	25,886,207 - 25,942,013 (-)	NCBI		HuRef
CHM1_1	2	26,079,044 - 26,135,487 (-)	NCBI		CHM1_1

Kif3c
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	3,415,132 - 3,456,494 (+)	NCBI	GRCm39		mm39
GRCm38	12	3,365,132 - 3,406,494 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	3,365,132 - 3,406,494 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	3,365,132 - 3,406,494 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	12	3,365,132 - 3,406,494 (+)	NCBI			mm8
Celera	12	3,292,187 - 3,333,551 (+)	NCBI		Celera
Cytogenetic Map	12	A1.1	NCBI
cM Map	12	1.77	NCBI

Kif3c
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955469	7,958,481 - 8,001,738 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955469	7,960,224 - 8,001,161 (-)	NCBI	ChiLan1.0	ChiLan1.0

KIF3C
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	2A	26,020,025 - 26,074,961 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	26,020,025 - 26,074,961 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	2A	25,927,039 - 25,982,715 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

KIF3C
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	17	20,091,759 - 20,128,562 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	17	20,090,374 - 20,128,703 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Kif3c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936493	6,396,606 - 6,435,266 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KIF3C
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	112,963,492 - 113,016,950 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	112,963,424 - 113,014,632 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	119,943,241 - 119,968,158 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KIF3C
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	81,666,884 - 81,717,489 (+)	NCBI
ChlSab1.1 Ensembl	14	81,666,793 - 81,717,508 (+)	Ensembl

Kif3c
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624738	8,128,594 - 8,171,638 (-)	NCBI

Position Markers

D6Wox30

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	6	27,814,671 - 27,814,893	NCBI	Rnor6.0
Rnor_5.0	6	37,624,943 - 37,625,165	UniSTS	Rnor5.0
RGSC_v3.4	6	26,380,293 - 26,380,515	UniSTS	RGSC3.4
Celera	6	25,881,772 - 25,881,994	UniSTS
Cytogenetic Map	6	q14	UniSTS

AW523935

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	6	27,815,688 - 27,815,843	NCBI	Rnor6.0
Rnor_5.0	6	37,625,960 - 37,626,115	UniSTS	Rnor5.0
RGSC_v3.4	6	26,381,310 - 26,381,465	UniSTS	RGSC3.4
Celera	6	25,882,789 - 25,882,944	UniSTS
Cytogenetic Map	6	q14	UniSTS
RH 3.4 Map	6	117.4	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
738023	Alc17	Alcohol consumption QTL 17	3.1	0.003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	6	1	35623029	Rat
1354616	Despr12	Despair related QTL 12		0.0012	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	6	1	35623029	Rat
1549905	Stresp10	Stress response QTL 10	6.83	0.0066	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	6	1	35623029	Rat
2300176	Bmd51	Bone mineral density QTL 51	11.7	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	6	1	35623029	Rat
2300190	Bmd52	Bone mineral density QTL 52	11.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	6	1	35623029	Rat
1331743	Uae28	Urinary albumin excretion QTL 28	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	1	41917988	Rat
9589048	Scfw3	Subcutaneous fat weight QTL 3	4.57	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	6	1	42388212	Rat
9589129	Insul24	Insulin level QTL 24	19.06	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	6	1	42388212	Rat
7411603	Foco13	Food consumption QTL 13	5.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1	42388212	Rat
7411542	Bw127	Body weight QTL 127	5.5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	1	42388212	Rat
8552962	Pigfal16	Plasma insulin-like growth factor 1 level QTL 16	9.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	6	1	42388212	Rat
2293709	Bss23	Bone structure and strength QTL 23	5.18	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	6	1	43665660	Rat
2293650	Bss31	Bone structure and strength QTL 31	5.05	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	6	1	43665660	Rat
2293656	Bss28	Bone structure and strength QTL 28	6.79	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	6	1	43665660	Rat
7411584	Foco4	Food consumption QTL 4	4.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1	44015370	Rat
738024	Sach5	Saccharine consumption QTL 5	3.9	0.00039	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	6	1	44570292	Rat
2301972	Bp325	Blood pressure QTL 325	4.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	1	75623393	Rat
1359023	Bp272	Blood pressure QTL 272	2.5		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	1120393	28706721	Rat
2292589	Emca10	Estrogen-induced mammary cancer QTL 10		0.048	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	6	1120393	46120393	Rat
1354664	Slep2	Serum leptin concentration QTL 2	4.49		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	6	1120393	75023446	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	2537030	111715717	Rat
1578665	Bss16	Bone structure and strength QTL 16	4.4		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	6	6161722	76002731	Rat
1578668	Bmd14	Bone mineral density QTL 14	3.8		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	6	6161722	76002731	Rat
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	7009971	115379601	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	10173862	55173862	Rat
1300128	Rf16	Renal function QTL 16	3.89		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	13122958	34367603	Rat
1300164	Rf15	Renal function QTL 15	3.12		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	13122958	57516539	Rat
10401812	Kidm54	Kidney mass QTL 54			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	16810107	61810107	Rat
10401800	Kidm49	Kidney mass QTL 49			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	16810107	61810107	Rat
8552910	Pigfal5	Plasma insulin-like growth factor 1 level QTL 5	4.3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	6	19417887	64417887	Rat
1641898	Colcr4	Colorectal carcinoma resistance QTL4	3.71	0.0007	intestine integrity trait (VT:0010554)	well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)	6	21515302	65784818	Rat
2293839	Kiddil2	Kidney dilation QTL 2	4.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	22042854	84763421	Rat
2293841	Kiddil4	Kidney dilation QTL 4	4.4		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	22042854	84763421	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	98
Count of miRNA genes:	84
Interacting mature miRNAs:	89
Transcripts:	ENSRNOT00000015820
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium			8		6				72	20	27	11
Low	3	43	36	28	13	28	8	11	2	15	14		8
Below cutoff			13	13		13

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AABR07063300	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AABR07063301	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AABR07063302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AABR07063303	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01042375	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF083330	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ223599	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000015820 ⟹ ENSRNOP00000015820

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	6	27,768,943 - 27,815,611 (+)	Ensembl

RefSeq Acc Id:

NM_053486 ⟹ NP_445938

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	27,768,943 - 27,815,611 (+)	NCBI
Rnor_5.0	6	37,579,445 - 37,625,883 (+)	NCBI
RGSC_v3.4	6	26,342,388 - 26,381,233 (+)	RGD
Celera	6	25,843,783 - 25,882,712 (+)	RGD

Sequence:

show sequence

CTGATCCCGACTTAGGAGTAAGGGCAGGAGGACCGCCCAGGCTGCAGAGCGGCCCACCTGGAAG
GACAGAGCTGCAAGATGGCCAGTAAGACCAAGGCCAGCGAGGCCCTGAAGGTGGTGGCCCGGTG
CCGCCCCCTCAGTAGGAAGGAGGAGGCTGCTGGTCATGAGCAGATTCTGACCATGGACGTGAAA
CTGGGCCAGGTGACTCTGCGAAACCCCCGCGCGGCACCCGGGGAGCTGCCCAAGACCTTCACTT
TTGATGCTGTGTATGACGCTAGCTCCAAGCAGGCCGACCTGTATGATGAAACGGTGAGGCCCCT
GATAGACTCGGTGCTTCAGGGTTTCAATGGCACCGTATTTGCCTATGGCCAGACTGGCACTGGC
AAGACCTACACCATGCAGGGGACCTGGGTGGAGCCAGAGCTCCGCGGGGTTATCCCCAATGCCT
TTGAGCACATCTTCACCCACATTTCCCGCTCCCAGAACCAGCAGTACCTGGTTCGTGCCTCCTA
CTTGGAGATCTACCAGGAGGAGATTCGAGACCTGCTATCCAAGGAGCCAGGCAAAAGGCTAGAA
CTGAAGGAGAATCCTGAAACAGGGGTCTACATCAAGGACCTCTCTTCCTTTGTCACCAAGAATG
TCAAGGAGATTGAACACGTGATGAACCTGGGGAACCAAGCCCGGGCAGTAGGCAGCACCCACAT
GAATGAGGTCAGCTCCCGGTCCCATGCCATCTTTGTTATCACAGTGGAGTGCAGTGAGCGTGGC
TCCGATGGACAGGACCATATCCGAGTAGGCAAGCTCAACCTGGTAGACCTGGCCGGCAGTGAGA
GGCAGAACAAGGCAGGTCCCAACACACCTGGAGGGCCAGCCACACAGTCAACAGCTGGTGGTGG
CGGCGGAGGTGGCGGCACTAGTGGTTCTGGCAGTAGTGGAGAGAGGCCTAAGGAAGCTTCTAAA
ATCAATCTTTCACTGTCCGCCCTGGGCAATGTGATTGCTGCTTTGGCTGGCAACAGGAGCACCC
ACATCCCCTACCGGGACTCCAAGCTGACCCGGCTGCTCCAAGACTCATTGGGGGGCAATGCCAA
GACCATCATGGTGGCCACACTGGGTCCAGCTTCTCATAGCTACGACGAGAGCCTCTCCACCCTG
CGCTTTGCGAACCGAGCCAAGAACATCAAGAACAAACCGCGGGTGAACGAGGACCCCAAGGACA
CGCTGCTTAGGGAATTCCAGGAAGAGATCGCCCGCTTGAAGGCCCAGCTTGAGAAGAAGGGGAT
GCTGGGAAAGCGACCTCGGAGAAAGAGCAGTCGCAGAAAGAAGGCCGTGTCTGCTCCGGCCGGC
TATCCAGAGGGGGCCGTAATTGAGGCTTGGGTGGCTGAAGAGGAAGATGATAACAACAATAATC
ACCGCCCACCCCAGCCCACCCTGGAGGCCGCTTTGGAGAAAAACATGGAGAATTACCTGCAGGA
ACAGAAAGAGCGGCTGGAGGAGGAGAAGGCGGCCATCCAGGATGACCGCAGCCTCGTGAGTGAG
GAGAAGCAGAAGCTTCTAGAAGAGAAGGAGAAGATGCTGGAGGATCTGAAGCGGGAGCAGCAGG
CCACAGAGCTGCTTGCAGCCAAGTACAAGGCCATGGAAAGCAAGCTACTCATTGGGGGGCGGAA
CATCATGGATCACACCAACGAACAACAGAAGATGTTGGAACTGAAGCGACAGGAGATTGCAGAA
CAGAAACGGCGTGAACGGGAAATGCAGCAGGAGATGCTGCTCCGAGATGAAGAGACCATGGAGC
TACGTGGTACCTACTCGTCCCTGCAGCAGGAGGTGGAAGTTAAAACCAAGAAACTCAAGAAGCT
CTATGCCAAGCTACAGGCGGTGAAGGCAGAGATCCAGGACCAACATGAGGAGTACATCCGCGTG
CGGCAGGACCTGGAGGAGGCGCAGAATGAGCAGACCCGGGAACTCAAGCTCAAGTACCTCATCA
TTGAGAACTTCATCCCCCCTGAGGAGAAGAACAAGATCATGAACCGGCTTTTCCTGGACTGTGA
GGAGGAGCAGTGGAAGTTCCAGCCCCTGGTGCCAGCTGGAGTGAATAACAGCCAAATGAAGAAG
CGTCCAACTTCTGCAGTGGGCTACAAGAGACCTATCAGCCAGTATGCTCGGGTTGCCATGGCAA
TGGGGTCCCATCCCAGATACAGGGCTGAAAATATAATGTTTTTGGAACTGGATGTATCCCCGCC
GGCCATCTTTGAGATGGAATTTTCTCATGACCAAGAACAAGATCCACGAGTACTACACATGGAG
AGGCTCATGCGGTTGGACAGCTTTCTGGAGAGACCTTCCACGTCTAAAGTGCGAAAGTCGAGAT
CCTGGTGCCAGAGTCCTCAGCGGCCTCCACCACCCTCCACAGTTCATGCCTCCATGGCCTCTGC
TCCTCTGCACCCTGCAACAGTGGTAGACCATGACTGACACCCTTCAGTCAGGCTGCCCATCACA
AAGACTCCTAGGACAGGGCAGCCATCCCTGGTTCATCCCATCTGATGCTTGGTGCGCGCGTGTG
TGGGGTGTGTATGCATGTGTGTGTGTGTGAACTAGTGTGTGTACTAGTGTGTGTGAAGGGGCAA
GAAACCGGCAGGTGGTGCCTCTGCCTGTTCTCCGGGCCTCCTTTATTTAATTCTGTTATTTATT
CGTGGAGCTTGGTTAGTGAGGAGAGATTCCCCTCGCTTGAGCTGCCTGGGCCTGCCATGGTCAC
TGCATAGCTTCCTGTTCTGGCTGAGGAGAGACCTCAGTCAGGCCCCAAGCTCCTCACGTCAGCT
GCCCCTGAGGGAAGATGGCTAGTGCCTGAGAAGACAGTGCTTCCTTTACCCGTCCAAGTTCACA
GTTTCCATCTTCTTGTCTGATGGTGAGCAGCCCCTGATGCTTTCTGAGGCTGGGAAACTGCGGG
TGTCCACTGAGGGCAAGAGGTGTCCTAACAGTGTTGGGCTTGCACTCCTGGTGGACTGAGCCTT
GCTCACCTCTTCCTGGGCCCTAAACTCTTCGAGCCTCCAGGGCTCTTTCCCAAGGACTTTCAGT
AGCCTAATACTCATCCCAGGCTCTCCGGCCTTGGCAAGAACTCGTGGCTTCCCCAACTCCACTT
CATTGCCAGCCCTCTCTACCCTGGGATTGGGAATTGTGAACCAAACAGTTGTTGCTACCACGAG
ACCTACAGGAAGTGGAACAGTGTGGAAAACGCATGGAATGTCATCAGGGGCACTCTCTCCTCAG
TTCCTCTGGTTTCCTTCTCTCCTCCAAGAAGTTCCTTTGGAGAACAAACCATCAGACTCCCTCT
CCTCATGTGAGGTGTAGCTTTTCCTGCTCTGATCACTGTTCCCTGAAGCTGTCAGGTCTCAGTC
CACAGTGGAAAGAATCGGTGTCATTCC

hide sequence

Protein Sequences


Protein RefSeqs	NP_445938	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC33291	(Get FASTA)	NCBI Sequence Viewer
	CAA11465	(Get FASTA)	NCBI Sequence Viewer
	EDM03007	(Get FASTA)	NCBI Sequence Viewer
	O55165	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_445938 ⟸ NM_053486

- UniProtKB:

O55165 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVY
DASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEHIF
THISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSSFVTKNVKEIE
HVMNLGNQARAVGSTHMNEVSSRSHAIFVITVECSERGSDGQDHIRVGKLNLVDLAGSERQNKA
GPNTPGGPATQSTAGGGGGGGGTSGSGSSGERPKEASKINLSLSALGNVIAALAGNRSTHIPYR
DSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLRE
FQEEIARLKAQLEKKGMLGKRPRRKSSRRKKAVSAPAGYPEGAVIEAWVAEEEDDNNNNHRPPQ
PTLEAALEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLKREQQATELL
AAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMLLRDEETMELRGTY
SSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHEEYIRVRQDLEEAQNEQTRELKLKYLIIENFI
PPEEKNKIMNRLFLDCEEEQWKFQPLVPAGVNNSQMKKRPTSAVGYKRPISQYARVAMAMGSHP
RYRAENIMFLELDVSPPAIFEMEFSHDQEQDPRVLHMERLMRLDSFLERPSTSKVRKSRSWCQS
PQRPPPPSTVHASMASAPLHPATVVDHD

hide sequence

RefSeq Acc Id:

ENSRNOP00000015820 ⟸ ENSRNOT00000015820

Protein Domains

Kinesin motor

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621538	AgrOrtholog
Ensembl Genes	ENSRNOG00000011394	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000015820	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000015820	ENTREZGENE, UniProtKB/TrEMBL
InterPro	Kinesin-like_fam	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Kinesin_motor_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Kinesin_motor_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:85248	UniProtKB/Swiss-Prot
NCBI Gene	85248	ENTREZGENE
PANTHER	PTHR24115	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Kinesin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Kif3c	PhenoGen
PRINTS	KINESINHEAVY	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	KINESIN_MOTOR_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	KINESIN_MOTOR_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	KISc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene	Rn.10894	ENTREZGENE
UniProt	G3V7J8_RAT	UniProtKB/TrEMBL
	KIF3C_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	O88657	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Kif3c	kinesin family member 3C			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Kif3c	kinesin family member 3C			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in brain, retina, and lung	729208
gene_function	binds to microtubules in a nucleotide-dependent manner	729208

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD