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Gene: Mtm1 (myotubularin 1) Rattus norvegicus
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Symbol: Mtm1
Name: myotubularin 1
Description: Predicted to have intermediate filament binding activity; phosphatase activity; and phosphatidylinositol binding activity. Predicted to be involved in several processes, including dephosphorylation; negative regulation of cellular catabolic process; and negative regulation of intracellular signal transduction. Predicted to localize to several cellular components, including the cytoplasm; filopodium; and ruffle. Human ortholog(s) of this gene implicated in centronuclear myopathy and congenital structural myopathy. Orthologous to human MTM1 (myotubularin 1); INTERACTS WITH 2,5-hexanedione; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC288762; MGC108964; myotubularin; phosphatidylinositol-3,5-bisphosphate 3-phosphatase; phosphatidylinositol-3-phosphate phosphatase; X-linked myotubular myopathy gene 1
Orthologs:
Homo sapiens (human) : MTM1 (myotubularin 1)  HGNC  Alliance
Mus musculus (house mouse) : Mtm1 (X-linked myotubular myopathy gene 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mtm1 (myotubularin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MTM1 (myotubularin 1)
Canis lupus familiaris (dog) : MTM1 (myotubularin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mtm1 (myotubularin 1)
Sus scrofa (pig) : MTM1 (myotubularin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0618,821,821 - 18,840,449 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0628,722,724 - 28,736,560 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47247,960 - 265,281 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17247,959 - 265,280 (+)NCBI
Celera6311,677 - 329,242 (-)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mtm1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1304582
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.