Gene: Abcg8 (ATP binding cassette subfamily G member 8) Rattus norvegicus
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Symbol: Abcg8
Name: ATP binding cassette subfamily G member 8
Description: ENCODES a protein that exhibits ATP binding (ortholog); ATPase activity (ortholog); ATPase activity, coupled to transmembrane movement of substances (ortholog); INVOLVED IN response to drug; response to nutrient; cholesterol efflux (ortholog); PARTICIPATES IN bile acid transport pathway; ASSOCIATED WITH cholestasis; Diabetes Mellitus, Experimental ; arteriosclerosis (ortholog); FOUND IN apical plasma membrane (ortholog); ATP-binding cassette (ABC) transporter complex (ortholog); integral component of plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol
AGR Description: Predicted to contribute to ATP binding activity, ATPase activity, and cholesterol transporter activity; involved in response to drug and response to nutrient; predicted to localize to several cellular components, including the ATP-binding activity cassette (ABC) transporter complex, apical plasma membrane, and integral component of plasma membrane; biomarker of cholestasis; orthologous to human ABCG8 (ATP binding cassette subfamily G member 8).
Merged Description: Predicted to contribute to ATP binding activity, ATPase activity, and cholesterol transporter activity; involved in response to drug and response to nutrient; predicted to localize to several cellular components, including the ATP-binding activity cassette (ABC) transporter complex, apical plasma membrane, and integral component of plasma membrane; biomarker of cholestasis; orthologous to human ABCG8 (ATP binding cassette subfamily G member 8); PARTICIPATES IN bile acid transport pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATP-binding cassette sub-family G member 8; ATP-binding cassette, sub-family G (WHITE), member 8; ATP-binding cassette, subfamily G (WHITE), member 8; sterolin 2; sterolin-2
Orthologs:
Homo sapiens (human) : ABCG8 (ATP binding cassette subfamily G member 8)  HGNC  Alliance
Mus musculus (house mouse) : Abcg8 (ATP binding cassette subfamily G member 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abcg8 (ATP binding cassette subfamily G member 8)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCG8 (ATP binding cassette subfamily G member 8)
Canis lupus familiaris (dog) : ABCG8 (ATP binding cassette subfamily G member 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcg8 (ATP binding cassette subfamily G member 8)
Sus scrofa (pig) : ABCG8 (ATP binding cassette subfamily G member 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.067,961,413 - 7,980,708 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.067,897,005 - 7,916,593 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.468,064,631 - 8,083,271 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.168,064,630 - 8,083,271 (+)NCBI
Celera69,667,270 - 9,686,500 (-)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Strain Sequence Variants (Rnor 5.0)
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Additional Information

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Nomenclature History
RGD Curation Notes
  
More on Abcg8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 620300
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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