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Gene: Lrpprc (leucine-rich pentatricopeptide repeat containing) Rattus norvegicus
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Symbol: Lrpprc
Name: leucine-rich pentatricopeptide repeat containing
Description: Predicted to have beta-tubulin binding activity; nucleic acid binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in negative regulation of mitochondrial RNA catabolic process and regulation of mitochondrial translation. Predicted to colocalize with the mitochondrion. Human ortholog(s) of this gene implicated in Leigh disease. Orthologous to human LRPPRC (leucine rich pentatricopeptide repeat containing); PARTICIPATES IN CRM1 export pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 130 kDa leucine-rich protein; leucine rich protein 157; leucine-rich PPR motif-containing protein, mitochondrial; leucine-rich PPR-motif containing; leucine-rich protein 157; LOC313867; LRP 130; Lrp157; rLRP157
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.067,984,043 - 8,066,874 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.067,919,928 - 8,001,949 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.468,086,606 - 8,168,261 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.168,086,606 - 8,168,261 (-)NCBI
Celera69,581,533 - 9,663,935 (+)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Lrpprc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306575
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.