Gene: Nlrc4 (NLR family, CARD domain containing 4) Rattus norvegicus
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Symbol: Nlrc4
Name: NLR family, CARD domain containing 4
Description: ENCODES a protein that exhibits ATP binding (ortholog); identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN activation of cysteine-type endopeptidase activity involved in apoptotic process (ortholog); activation of innate immune response (ortholog); defense response to bacterium (ortholog); ASSOCIATED WITH Autoinflammation with Infantile Enterocolitis (ortholog); Cryopyrin-Associated Periodic Syndromes (ortholog); Enterocolitis (ortholog); FOUND IN cytosol (ortholog); IPAF inflammasome complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; endosulfan
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Card12; caspase recruitment domain family, member 12; ice protease-activating factor; ipaf; LOC298784; NLR family CARD domain-containing protein 4
Orthologs:
Homo sapiens (human) : NLRC4 (NLR family CARD domain containing 4)  HGNC  Alliance
Mus musculus (house mouse) : Nlrc4 (NLR family, CARD domain containing 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nlrc4 (NLR family CARD domain containing 4)
Pan paniscus (bonobo/pygmy chimpanzee) : NLRC4 (NLR family CARD domain containing 4)
Canis lupus familiaris (dog) : NLRC4 (NLR family CARD domain containing 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nlrc4 (NLR family CARD domain containing 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0622,167,874 - 22,194,755 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0632,058,459 - 32,081,799 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4620,934,595 - 20,953,654 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1620,933,896 - 20,956,415 (+)NCBI
Celera620,554,800 - 20,577,780 (+)NCBICelera
Cytogenetic Map6q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Nlrc4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309831
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2018-10-09
Status: ACTIVE