Gene: Kcnk3 (potassium two pore domain channel subfamily K member 3) Rattus norvegicus
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Symbol: Kcnk3
Name: potassium two pore domain channel subfamily K member 3
Description: ENCODES a protein that exhibits open rectifier potassium channel activity; protein C-terminus binding; ion channel activity (ortholog); INVOLVED IN brain development; cellular response to hypoxia; cellular response to zinc ion; ASSOCIATED WITH Deafness; status epilepticus; Gliosis (ortholog); FOUND IN plasma membrane; INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; ammonium chloride
AGR Description: Exhibits open rectifier potassium channel activity and protein C-terminus binding activity; involved in several processes, including animal organ development, cellular response to hypoxia, and cellular response to zinc ion; localizes to the plasma membrane; biomarker of status epilepticus; orthologous to human KCNK3 (potassium two pore domain channel subfamily K member 3).
Merged Description: Exhibits open rectifier potassium channel activity and protein C-terminus binding activity; involved in several processes, including animal organ development, cellular response to hypoxia, and cellular response to zinc ion; localizes to the plasma membrane; biomarker of status epilepticus; orthologous to human KCNK3 (potassium two pore domain channel subfamily K member 3); INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: acid-sensitive potassium channel protein TASK-1; potassium channel subfamily K member 3; potassium channel, subfamily K, member 3; potassium channel, two pore domain subfamily K, member 3; rTASK; Task-1; TWIK-related acid-sensitive K(+) channel 1; TWIK-related acid-sensitive K+ channel; two pore K(+) channel KT3.1; two pore potassium channel KT3.1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0627,154,274 - 27,190,209 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0636,969,843 - 37,005,778 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4625,745,923 - 25,782,144 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1625,748,881 - 25,785,097 (-)NCBI
Celera625,246,393 - 25,282,199 (-)NCBICelera
Cytogenetic Map6q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kcnk3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61997
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.