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Gene: Kcnk3 (potassium two pore domain channel subfamily K member 3) Rattus norvegicus
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Symbol: Kcnk3
Name: potassium two pore domain channel subfamily K member 3
Description: Exhibits open rectifier potassium channel activity and protein C-terminus binding activity. Involved in several processes, including cellular response to zinc ion; cochlea development; and negative regulation of cytosolic calcium ion concentration. Localizes to the plasma membrane. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in primary pulmonary hypertension. Orthologous to human KCNK3 (potassium two pore domain channel subfamily K member 3); INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: acid-sensitive potassium channel protein TASK-1; potassium channel subfamily K member 3; potassium channel, subfamily K, member 3; potassium channel, two pore domain subfamily K, member 3; rTASK; Task-1; TWIK-related acid-sensitive K(+) channel 1; TWIK-related acid-sensitive K+ channel; two pore K(+) channel KT3.1; two pore potassium channel KT3.1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0627,154,274 - 27,190,209 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl627,151,612 - 27,190,132 (-)Ensembl
Rnor_5.0636,969,843 - 37,005,778 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4625,745,923 - 25,782,144 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1625,748,881 - 25,785,097 (-)NCBI
Celera625,246,393 - 25,282,199 (-)NCBICelera
Cytogenetic Map6q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kcnk3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61997
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.