Plekhh2 (pleckstrin homology, MyTH4 and FERM domain containing H2) - Rat Genome Database

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Gene: Plekhh2 (pleckstrin homology, MyTH4 and FERM domain containing H2) Rattus norvegicus
Analyze
Symbol: Plekhh2
Name: pleckstrin homology, MyTH4 and FERM domain containing H2
RGD ID: 1304935
Description: Predicted to enable actin binding activity. Predicted to be involved in negative regulation of actin filament depolymerization. Predicted to be located in several cellular components, including cortical actin cytoskeleton; lamellipodium; and nuclear body. Predicted to be active in cytoplasm. Orthologous to human PLEKHH2 (pleckstrin homology, MyTH4 and FERM domain containing H2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC313866; pleckstrin homology domain containing, family H (with MyTH4 domain) member 2; pleckstrin homology domain-containing family H member 2; RGD1304935; similar to CG12467-PA
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8615,783,179 - 15,893,479 (-)NCBIGRCr8
mRatBN7.2610,032,837 - 10,132,081 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl610,032,660 - 10,140,794 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx610,328,232 - 10,428,034 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0610,637,621 - 10,737,423 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0610,155,943 - 10,253,050 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.067,784,743 - 7,895,986 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl67,793,735 - 7,893,769 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.067,731,647 - 7,830,438 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.467,887,555 - 7,986,077 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.167,887,554 - 7,986,077 (+)NCBI
Celera69,753,640 - 9,852,005 (-)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
actin binding  (IBA,ISO)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:22832517  


Genomics

Comparative Map Data
Plekhh2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8615,783,179 - 15,893,479 (-)NCBIGRCr8
mRatBN7.2610,032,837 - 10,132,081 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl610,032,660 - 10,140,794 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx610,328,232 - 10,428,034 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0610,637,621 - 10,737,423 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0610,155,943 - 10,253,050 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.067,784,743 - 7,895,986 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl67,793,735 - 7,893,769 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.067,731,647 - 7,830,438 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.467,887,555 - 7,986,077 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.167,887,554 - 7,986,077 (+)NCBI
Celera69,753,640 - 9,852,005 (-)NCBICelera
Cytogenetic Map6q12NCBI
PLEKHH2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38243,637,260 - 43,767,987 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl243,637,260 - 43,767,987 (+)EnsemblGRCh38hg38GRCh38
GRCh37243,864,399 - 43,995,126 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36243,717,951 - 43,848,630 (+)NCBINCBI36Build 36hg18NCBI36
Build 34243,776,097 - 43,906,776NCBI
Celera243,703,213 - 43,833,863 (+)NCBICelera
Cytogenetic Map2p21NCBI
HuRef243,600,415 - 43,731,823 (+)NCBIHuRef
CHM1_1243,794,022 - 43,924,517 (+)NCBICHM1_1
T2T-CHM13v2.0243,642,678 - 43,773,318 (+)NCBIT2T-CHM13v2.0
Plekhh2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391784,819,303 - 84,929,571 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1784,819,323 - 84,929,566 (+)EnsemblGRCm39 Ensembl
GRCm381784,511,895 - 84,622,143 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1784,511,895 - 84,622,138 (+)EnsemblGRCm38mm10GRCm38
MGSCv371784,911,235 - 85,021,482 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361784,420,221 - 84,530,455 (+)NCBIMGSCv36mm8
Celera1788,877,452 - 88,989,118 (+)NCBICelera
Cytogenetic Map17E4NCBI
cM Map1755.02NCBI
Plekhh2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544110,825,499 - 10,919,901 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544110,818,982 - 10,921,224 (+)NCBIChiLan1.0ChiLan1.0
PLEKHH2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21282,655,725 - 82,784,297 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A82,659,697 - 82,788,358 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A43,723,791 - 43,852,380 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A44,570,356 - 44,700,272 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A44,570,356 - 44,700,272 (+)Ensemblpanpan1.1panPan2
PLEKHH2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11046,113,659 - 46,226,259 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1046,114,348 - 46,224,363 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1045,975,843 - 46,087,889 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01046,992,023 - 47,104,761 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1046,992,060 - 47,103,049 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11046,700,351 - 46,813,125 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01046,990,837 - 47,103,309 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01047,173,714 - 47,286,463 (+)NCBIUU_Cfam_GSD_1.0
Plekhh2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629236,724,758 - 36,840,159 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365088,153,122 - 8,268,779 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365088,153,367 - 8,268,760 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHH2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl396,709,059 - 96,833,410 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1396,707,397 - 96,833,431 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23102,783,515 - 102,863,985 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLEKHH2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11463,488,305 - 63,617,146 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1463,488,773 - 63,609,021 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604548,277,182 - 48,402,709 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekhh2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473825,123,506 - 25,239,175 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473825,122,843 - 25,240,304 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Plekhh2
1020 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:101
Count of miRNA genes:82
Interacting mature miRNAs:88
Transcripts:ENSRNOT00000006832
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6141223769Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6139036266Rat
738024Sach5Saccharine consumption QTL 53.90.00039consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)6143394190Rat
1549905Stresp10Stress response QTL 106.830.0066stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)6127574569Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6141223769Rat
2293706Bmd20Bone mineral density QTL 204.30.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)6507449719988050Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6141223769Rat
2292616Ept15Estrogen-induced pituitary tumorigenesis QTL 154.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6984331220338915Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)6134235784Rat
738023Alc17Alcohol consumption QTL 173.10.003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)6127574569Rat
1354616Despr12Despair related QTL 120.0012locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)6127574569Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6142487980Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6142487980Rat
7411584Foco4Food consumption QTL 44.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6142838846Rat
2300176Bmd51Bone mineral density QTL 5111.70.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)6127574569Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449734434305Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6142487980Rat
1358190Ept1Estrogen-induced pituitary tumorigenesis QTL 14.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6984331220338915Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
2300190Bmd52Bone mineral density QTL 5211.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)6127574569Rat
1578758Tcas9Tongue tumor susceptibility QTL 93.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)6137618905Rat

Markers in Region
BF404107  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2610,104,101 - 10,104,278 (-)MAPPERmRatBN7.2
Rnor_6.067,821,732 - 7,821,908NCBIRnor6.0
Rnor_6.067,734,558 - 7,734,734NCBIRnor6.0
Rnor_5.067,673,754 - 7,673,930UniSTSRnor5.0
Rnor_5.067,759,524 - 7,759,700UniSTSRnor5.0
RGSC_v3.467,915,293 - 7,915,469UniSTSRGSC3.4
Celera69,824,294 - 9,824,470UniSTS
Cytogenetic Map6q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001191770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008764463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017594123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063261849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC120701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000006832   ⟹   ENSRNOP00000006832
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl610,032,660 - 10,140,794 (-)Ensembl
Rnor_6.0 Ensembl67,793,855 - 7,893,519 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090724   ⟹   ENSRNOP00000072102
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl67,793,735 - 7,893,769 (+)Ensembl
RefSeq Acc Id: NM_001191770   ⟹   NP_001178699
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,785,646 - 15,884,745 (-)NCBI
mRatBN7.2610,032,837 - 10,132,081 (-)NCBI
Rnor_6.067,793,855 - 7,893,519 (+)NCBI
Rnor_5.067,731,647 - 7,830,438 (+)NCBI
Celera69,753,640 - 9,852,005 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063261830   ⟹   XP_063117900
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,783,179 - 15,893,159 (-)NCBI
RefSeq Acc Id: XM_063261831   ⟹   XP_063117901
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,783,179 - 15,893,479 (-)NCBI
RefSeq Acc Id: XM_063261832   ⟹   XP_063117902
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,783,179 - 15,893,159 (-)NCBI
RefSeq Acc Id: XM_063261833   ⟹   XP_063117903
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,783,179 - 15,865,827 (-)NCBI
RefSeq Acc Id: XM_063261834   ⟹   XP_063117904
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,783,179 - 15,865,195 (-)NCBI
RefSeq Acc Id: XM_063261835   ⟹   XP_063117905
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,783,179 - 15,893,159 (-)NCBI
RefSeq Acc Id: XM_063261836   ⟹   XP_063117906
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,783,179 - 15,868,082 (-)NCBI
RefSeq Acc Id: XM_063261837   ⟹   XP_063117907
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,783,179 - 15,867,970 (-)NCBI
RefSeq Acc Id: XM_063261838   ⟹   XP_063117908
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,783,179 - 15,893,159 (-)NCBI
RefSeq Acc Id: XM_063261839   ⟹   XP_063117909
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,783,179 - 15,884,675 (-)NCBI
RefSeq Acc Id: XM_063261840   ⟹   XP_063117910
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,783,179 - 15,893,107 (-)NCBI
RefSeq Acc Id: XM_063261841   ⟹   XP_063117911
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,783,179 - 15,893,104 (-)NCBI
RefSeq Acc Id: XM_063261842   ⟹   XP_063117912
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,808,614 - 15,893,159 (-)NCBI
RefSeq Acc Id: XM_063261843   ⟹   XP_063117913
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,783,179 - 15,868,078 (-)NCBI
RefSeq Acc Id: XM_063261844   ⟹   XP_063117914
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,783,179 - 15,868,007 (-)NCBI
RefSeq Acc Id: XM_063261846   ⟹   XP_063117916
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,783,179 - 15,893,104 (-)NCBI
RefSeq Acc Id: XM_063261847   ⟹   XP_063117917
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,783,179 - 15,843,658 (-)NCBI
RefSeq Acc Id: XM_063261848   ⟹   XP_063117918
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,783,179 - 15,840,929 (-)NCBI
RefSeq Acc Id: XM_063261849   ⟹   XP_063117919
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,783,179 - 15,840,930 (-)NCBI
RefSeq Acc Id: XR_010052082
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,808,614 - 15,893,159 (-)NCBI
RefSeq Acc Id: NP_001178699   ⟸   NM_001191770
- UniProtKB: D3ZNS6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006832   ⟸   ENSRNOT00000006832
Ensembl Acc Id: ENSRNOP00000072102   ⟸   ENSRNOT00000090724
RefSeq Acc Id: XP_063117901   ⟸   XM_063261831
- Peptide Label: isoform X1
- UniProtKB: D3ZNS6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117902   ⟸   XM_063261832
- Peptide Label: isoform X2
- UniProtKB: D3ZNS6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117908   ⟸   XM_063261838
- Peptide Label: isoform X7
- UniProtKB: D3ZNS6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117905   ⟸   XM_063261835
- Peptide Label: isoform X5
- UniProtKB: D3ZNS6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117900   ⟸   XM_063261830
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063117910   ⟸   XM_063261840
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063117911   ⟸   XM_063261841
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063117916   ⟸   XM_063261846
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063117909   ⟸   XM_063261839
- Peptide Label: isoform X8
- UniProtKB: D3ZNS6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117906   ⟸   XM_063261836
- Peptide Label: isoform X6
- UniProtKB: D3ZNS6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117913   ⟸   XM_063261843
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063117914   ⟸   XM_063261844
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063117907   ⟸   XM_063261837
- Peptide Label: isoform X6
- UniProtKB: D3ZNS6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117903   ⟸   XM_063261833
- Peptide Label: isoform X3
- UniProtKB: D3ZNS6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117904   ⟸   XM_063261834
- Peptide Label: isoform X4
- UniProtKB: D3ZNS6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117917   ⟸   XM_063261847
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063117919   ⟸   XM_063261849
- Peptide Label: isoform X16
RefSeq Acc Id: XP_063117918   ⟸   XM_063261848
- Peptide Label: isoform X15
RefSeq Acc Id: XP_063117912   ⟸   XM_063261842
- Peptide Label: isoform X11
Protein Domains
FERM   MyTH4   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K246-F1-model_v2 AlphaFold A0A0G2K246 1-1514 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304935 AgrOrtholog
BioCyc Gene G2FUF-38640 BioCyc
Ensembl Genes ENSRNOG00000005124 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006832.5 UniProtKB/TrEMBL
Gene3D-CATH 1.20.80.10 UniProtKB/TrEMBL
  1.25.40.530 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro Band_41_domain UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_3-hlx UniProtKB/TrEMBL
  FERM_2 UniProtKB/TrEMBL
  FERM_central UniProtKB/TrEMBL
  FERM_domain UniProtKB/TrEMBL
  MyTH4_dom UniProtKB/TrEMBL
  MyTH4_dom_sf UniProtKB/TrEMBL
  PH_like_dom UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
NCBI Gene 313866 ENTREZGENE
PANTHER PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 2 UniProtKB/TrEMBL
  PLEKHH PROTEIN UniProtKB/TrEMBL
Pfam FERM_M UniProtKB/TrEMBL
  MyTH4 UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
PhenoGen Plekhh2 PhenoGen
PROSITE FERM_3 UniProtKB/TrEMBL
  MYTH4 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005124 RatGTEx
SMART B41 UniProtKB/TrEMBL
  MyTH4 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP FERM_3-hlx UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
UniProt D3ZNS6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-30 Plekhh2  pleckstrin homology, MyTH4 and FERM domain containing H2  Plekhh2  pleckstrin homology domain containing, family H (with MyTH4 domain) member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Plekhh2  pleckstrin homology domain containing, family H (with MyTH4 domain) member 2  RGD1304935_predicted  similar to CG12467-PA (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1304935_predicted  similar to CG12467-PA (predicted)  LOC313866_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC313866_predicted  similar to CG12467-PA (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL