Gene: Cad (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase) Rattus norvegicus
Symbol: Cad
Name: carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Description: ENCODES a protein that exhibits aspartate carbamoyltransferase activity; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; dihydroorotase activity; INVOLVED IN 'de novo' pyrimidine nucleobase biosynthetic process; animal organ regeneration; cellular response to drug; PARTICIPATES IN 2-hydroxyglutaricaciduria disease pathway; beta-ureidopropionase deficiency pathway; Canavan disease pathway; ASSOCIATED WITH Carcinoma, Hepatocellular; diabetes mellitus, experimental; Fetal Growth Retardation; FOUND IN cell projection; cytosol; neuronal cell body; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene
Type: protein-coding
RefSeq Status: INFERRED
Also known as: Cad_mapped; Carbamyl phosphatate synthetase; carbamyl phosphatate synthetase 2; carbamyl phosphatate synthetase 2 (mapped)
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0626,657,507 - 26,680,459 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0636,472,498 - 36,495,450 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4625,272,416 - 25,296,266 (-)NCBIRGSC3.4rn4RGSC3.4
Celera624,783,039 - 24,805,943 (-)NCBICelera
Cytogenetic Map6q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Cad
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1588606
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2018-03-13
Status: ACTIVE