Msra (methionine sulfoxide reductase A) - Rat Genome Database

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Gene: Msra (methionine sulfoxide reductase A) Rattus norvegicus
Analyze
Symbol: Msra
Name: methionine sulfoxide reductase A
RGD ID: 70979
Description: Enables peptide-methionine (S)-S-oxide reductase activity. Predicted to be involved in cellular response to oxidative stress. Predicted to be located in several cellular components, including actin cytoskeleton; midbody; and nucleoplasm. Predicted to be active in cytoplasm. Orthologous to human MSRA (methionine sulfoxide reductase A); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC93315; mitochondrial peptide methionine sulfoxide reductase; peptide Met(O) reductase; peptide methionine sulfoxide reductase; peptide-methionine (S)-S-oxide reductase; PMSR; protein-methionine-S-oxide reductase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Allele / Splice: Msraem3Mcwi   Msraem4Mcwi  
Genetic Models: SS-Msraem4Mcwi SS-Msraem3Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81542,514,818 - 42,853,278 (-)NCBIGRCr8
mRatBN7.21538,363,459 - 38,677,406 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1538,351,445 - 38,676,585 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1540,220,249 - 40,540,125 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01541,370,932 - 41,690,814 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01539,824,072 - 40,137,073 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01547,488,333 - 47,800,662 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1547,488,894 - 47,800,024 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01551,307,920 - 51,550,758 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41543,509,775 - 43,756,283 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11543,543,986 - 43,771,983 (-)NCBI
Celera1538,127,708 - 38,353,451 (-)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
5-aza-2'-deoxycytidine  (ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cadmium sulfide  (ISO)
carbamazepine  (ISO)
carbon atom  (ISO)
cerium trichloride  (ISO)
chloramine T  (ISO)
chromium(6+)  (ISO)
cisplatin  (EXP,ISO)
copper(II) sulfate  (ISO)
DDT  (EXP)
diarsenic trioxide  (ISO)
dioxygen  (EXP)
elemental carbon  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
herbicide  (ISO)
inulin  (ISO)
ivermectin  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodiethylamine  (EXP)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
nicotinamide  (ISO)
O-methyleugenol  (ISO)
ochratoxin A  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
permethrin  (EXP)
picloram  (ISO)
propanal  (ISO)
reactive oxygen species  (EXP)
resveratrol  (ISO)
S-methylcysteine  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
tunicamycin  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Iron, ferritin and proteins of the methionine-centered redox cycle in young and old rat hearts. Bulvik B, etal., Mech Ageing Dev. 2009 Mar;130(3):139-44. Epub 2008 Oct 17.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Identification of a new functional splice variant of the enzyme methionine sulphoxide reductase A (MSRA) expressed in rat vascular smooth muscle cells. Haenold R, etal., Free Radic Res. 2007 Nov;41(11):1233-45.
5. Gene Data Set MGD Curation, June 12, 2002
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. Rat peptide methionine sulphoxide reductase: cloning of the cDNA, and down-regulation of gene expression and enzyme activity during aging. Petropoulos I, etal., Biochem J 2001 May 1;355(Pt 3):819-25.
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11606777   PMID:12477932   PMID:14745014   PMID:15489334   PMID:18083115   PMID:18614015   PMID:19056867   PMID:19085252   PMID:19646993   PMID:20368336   PMID:21726174   PMID:23036869  
PMID:23376485   PMID:24120970   PMID:24315642   PMID:25602783   PMID:30717164  


Genomics

Comparative Map Data
Msra
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81542,514,818 - 42,853,278 (-)NCBIGRCr8
mRatBN7.21538,363,459 - 38,677,406 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1538,351,445 - 38,676,585 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1540,220,249 - 40,540,125 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01541,370,932 - 41,690,814 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01539,824,072 - 40,137,073 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01547,488,333 - 47,800,662 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1547,488,894 - 47,800,024 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01551,307,920 - 51,550,758 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41543,509,775 - 43,756,283 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11543,543,986 - 43,771,983 (-)NCBI
Celera1538,127,708 - 38,353,451 (-)NCBICelera
Cytogenetic Map15p12NCBI
MSRA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38810,054,292 - 10,428,891 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl810,054,292 - 10,428,891 (+)EnsemblGRCh38hg38GRCh38
GRCh3789,911,802 - 10,286,401 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3689,949,236 - 10,323,805 (+)NCBINCBI36Build 36hg18NCBI36
Build 3489,949,235 - 10,323,803NCBI
Celera89,038,143 - 9,413,201 (+)NCBICelera
Cytogenetic Map8p23.1NCBI
HuRef88,840,844 - 9,216,822 (+)NCBIHuRef
CHM1_189,977,395 - 10,352,199 (+)NCBICHM1_1
T2T-CHM13v2.089,310,290 - 9,686,356 (-)NCBIT2T-CHM13v2.0
Msra
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391464,360,070 - 64,693,352 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1464,360,074 - 64,693,352 (-)EnsemblGRCm39 Ensembl
GRCm381464,122,621 - 64,455,903 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1464,122,625 - 64,455,903 (-)EnsemblGRCm38mm10GRCm38
MGSCv371464,741,462 - 65,074,740 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361463,076,735 - 63,410,013 (-)NCBIMGSCv36mm8
Celera1461,900,138 - 62,232,246 (-)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1433.36NCBI
Msra
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540351,730,156 - 52,071,269 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540351,729,753 - 52,071,269 (+)NCBIChiLan1.0ChiLan1.0
MSRA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2726,500,353 - 26,924,492 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan182,532,861 - 2,953,775 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v088,751,846 - 9,163,355 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
MSRA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12527,608,987 - 28,043,461 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2527,609,349 - 28,043,271 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2528,256,191 - 28,688,850 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02527,767,761 - 28,194,963 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2527,766,608 - 28,194,969 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12527,722,315 - 28,155,074 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02527,616,218 - 28,042,765 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02527,771,061 - 28,204,784 (-)NCBIUU_Cfam_GSD_1.0
Msra
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049436,154,114 - 6,480,295 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366752,106,116 - 2,434,460 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366752,104,618 - 2,432,033 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MSRA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1413,335,420 - 13,768,423 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11413,334,731 - 13,718,914 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21414,869,083 - 15,060,689 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MSRA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.188,664,040 - 9,026,632 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl88,663,034 - 8,993,433 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605233,390,875 - 33,760,411 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Msra
1266 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:288
Count of miRNA genes:91
Interacting mature miRNAs:100
Transcripts:ENSRNOT00000016616, ENSRNOT00000071197, ENSRNOT00000072997
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat

Markers in Region
D15Got43  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21538,668,278 - 38,668,448 (+)MAPPERmRatBN7.2
Rnor_6.01547,791,819 - 47,791,986NCBIRnor6.0
Rnor_5.01551,542,543 - 51,542,710UniSTSRnor5.0
RGSC_v3.41543,748,067 - 43,748,235RGDRGSC3.4
RGSC_v3.41543,748,068 - 43,748,235UniSTSRGSC3.4
RGSC_v3.11543,763,768 - 43,763,935RGD
Celera1538,345,236 - 38,345,403UniSTS
RH 3.4 Map15289.9UniSTS
RH 3.4 Map15289.9RGD
RH 2.0 Map15261.3RGD
Cytogenetic Map15p12UniSTS
D15Got44  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21538,536,732 - 38,536,957 (+)MAPPERmRatBN7.2
Rnor_6.01547,660,913 - 47,661,137NCBIRnor6.0
Rnor_5.01551,412,733 - 51,412,957UniSTSRnor5.0
RGSC_v3.41543,615,579 - 43,615,804RGDRGSC3.4
RGSC_v3.41543,615,580 - 43,615,804UniSTSRGSC3.4
RGSC_v3.11543,631,279 - 43,631,504RGD
Celera1538,214,714 - 38,214,938UniSTS
RH 2.0 Map15261.4RGD
Cytogenetic Map15p12UniSTS
D15Got227  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21538,645,845 - 38,646,060 (+)MAPPERmRatBN7.2
Rnor_6.01547,770,514 - 47,770,728NCBIRnor6.0
Rnor_5.01551,521,238 - 51,521,452UniSTSRnor5.0
RGSC_v3.41543,725,663 - 43,725,877UniSTSRGSC3.4
Celera1538,323,317 - 38,323,531UniSTS
Cytogenetic Map15p12UniSTS
RH137586  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15p12UniSTS
AU048707  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21538,615,789 - 38,615,967 (+)MAPPERmRatBN7.2
Rnor_6.01547,740,442 - 47,740,619NCBIRnor6.0
Rnor_5.01551,491,166 - 51,491,343UniSTSRnor5.0
RGSC_v3.41543,695,214 - 43,695,391UniSTSRGSC3.4
Celera1538,293,281 - 38,293,462UniSTS
Cytogenetic Map15p12UniSTS
AU049139  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21538,656,746 - 38,656,893 (+)MAPPERmRatBN7.2
Rnor_6.01547,781,415 - 47,781,561NCBIRnor6.0
Rnor_5.01551,532,139 - 51,532,285UniSTSRnor5.0
RGSC_v3.41543,736,565 - 43,736,711UniSTSRGSC3.4
Cytogenetic Map15p12UniSTS


Genetic Models
This gene Msra is modified in the following models/strains:


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 28 40 25 7 25 1 3 68 35 15 11 1
Low 15 17 16 12 16 7 8 6 26 7
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000016616   ⟹   ENSRNOP00000016616
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1538,351,445 - 38,676,555 (-)Ensembl
Rnor_6.0 Ensembl1547,488,928 - 47,800,024 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000072997   ⟹   ENSRNOP00000067242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1538,363,463 - 38,676,486 (-)Ensembl
Rnor_6.0 Ensembl1547,488,894 - 47,800,024 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095387   ⟹   ENSRNOP00000096051
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1538,363,463 - 38,651,182 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000101265   ⟹   ENSRNOP00000084705
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1538,363,461 - 38,676,486 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000102126   ⟹   ENSRNOP00000097940
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1538,363,463 - 38,676,585 (-)Ensembl
RefSeq Acc Id: NM_053307   ⟹   NP_445759
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81542,539,360 - 42,852,366 (-)NCBI
mRatBN7.21538,363,462 - 38,676,496 (-)NCBI
Rnor_6.01547,488,333 - 47,800,034 (-)NCBI
Rnor_5.01551,307,920 - 51,550,758 (-)NCBI
RGSC_v3.41543,509,775 - 43,756,283 (-)RGD
Celera1538,127,708 - 38,353,451 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039093214   ⟹   XP_038949142
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81542,539,357 - 42,853,278 (-)NCBI
mRatBN7.21538,363,462 - 38,677,406 (-)NCBI
RefSeq Acc Id: XM_039093215   ⟹   XP_038949143
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81542,539,357 - 42,746,522 (-)NCBI
mRatBN7.21538,363,459 - 38,570,644 (-)NCBI
RefSeq Acc Id: XM_039093216   ⟹   XP_038949144
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81542,539,357 - 42,827,100 (-)NCBI
mRatBN7.21538,363,459 - 38,651,197 (-)NCBI
RefSeq Acc Id: XM_039093218   ⟹   XP_038949146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81542,539,357 - 42,801,014 (-)NCBI
mRatBN7.21538,363,459 - 38,625,131 (-)NCBI
RefSeq Acc Id: XM_063274183   ⟹   XP_063130253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81542,539,357 - 42,827,327 (-)NCBI
RefSeq Acc Id: XR_010057810
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81542,514,818 - 42,852,402 (-)NCBI
RefSeq Acc Id: NP_445759   ⟸   NM_053307
- UniProtKB: A9LAT3 (UniProtKB/Swiss-Prot),   A9LAT4 (UniProtKB/Swiss-Prot),   Q923M1 (UniProtKB/Swiss-Prot),   A0A8I6A0P8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000067242   ⟸   ENSRNOT00000072997
RefSeq Acc Id: ENSRNOP00000016616   ⟸   ENSRNOT00000016616
RefSeq Acc Id: XP_038949144   ⟸   XM_039093216
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AN14 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949146   ⟸   XM_039093218
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038949143   ⟸   XM_039093215
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038949142   ⟸   XM_039093214
- Peptide Label: isoform X1
- UniProtKB: Q923M1 (UniProtKB/Swiss-Prot),   A9LAT3 (UniProtKB/Swiss-Prot),   A9LAT4 (UniProtKB/Swiss-Prot),   A0A8I6A0P8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000096051   ⟸   ENSRNOT00000095387
RefSeq Acc Id: ENSRNOP00000097940   ⟸   ENSRNOT00000102126
RefSeq Acc Id: ENSRNOP00000084705   ⟸   ENSRNOT00000101265
RefSeq Acc Id: XP_063130253   ⟸   XM_063274183
- Peptide Label: isoform X4
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q923M1-F1-model_v2 AlphaFold Q923M1 1-233 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699784
Promoter ID:EPDNEW_R10308
Type:initiation region
Name:Msra_1
Description:methionine sulfoxide reductase A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01547,800,066 - 47,800,126EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70979 AgrOrtholog
BioCyc Gene G2FUF-13386 BioCyc
Ensembl Genes ENSRNOG00000012440 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055006610 UniProtKB/Swiss-Prot
  ENSRNOG00060021859 UniProtKB/Swiss-Prot
  ENSRNOG00065029301 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000016616.7 UniProtKB/TrEMBL
  ENSRNOT00000072997.4 UniProtKB/TrEMBL
  ENSRNOT00000095387.1 UniProtKB/TrEMBL
  ENSRNOT00000101265.1 UniProtKB/TrEMBL
  ENSRNOT00000102126 ENTREZGENE
  ENSRNOT00000102126.1 UniProtKB/Swiss-Prot
  ENSRNOT00055010759 UniProtKB/Swiss-Prot
  ENSRNOT00060038293 UniProtKB/Swiss-Prot
  ENSRNOT00065050711 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.1060.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7107102 IMAGE-MGC_LOAD
InterPro Met_Sox_Rdtase_MsrA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Met_Sox_Rdtase_MsrA_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29447 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93315 IMAGE-MGC_LOAD
NCBI Gene 29447 ENTREZGENE
PANTHER MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE UniProtKB/Swiss-Prot
  MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE UniProtKB/Swiss-Prot
  MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE UniProtKB/TrEMBL
  MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE UniProtKB/TrEMBL
Pfam PMSR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Msra PhenoGen
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012440 RatGTEx
  ENSRNOG00055006610 RatGTEx
  ENSRNOG00060021859 RatGTEx
  ENSRNOG00065029301 RatGTEx
Superfamily-SCOP SSF55068 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A0P8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AN14 ENTREZGENE, UniProtKB/TrEMBL
  A6K6H7_RAT UniProtKB/TrEMBL
  A9LAT3 ENTREZGENE
  A9LAT4 ENTREZGENE
  F1LSJ6_RAT UniProtKB/TrEMBL
  M0RCC8_RAT UniProtKB/TrEMBL
  MSRA_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A9LAT3 UniProtKB/Swiss-Prot
  A9LAT4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-07-09 Msra  methionine sulfoxide reductase A      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expression may decrease with age 70794