Gene: Msra (methionine sulfoxide reductase A) Rattus norvegicus
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Symbol: Msra
Name: methionine sulfoxide reductase A
Description: ENCODES a protein that exhibits peptide-methionine (S)-S-oxide reductase activity; INVOLVED IN aging; ASSOCIATED WITH autistic disorder (ortholog); schizophrenia (ortholog); substance-related disorder (ortholog); FOUND IN cytoplasm; mitochondrion; actin cytoskeleton (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
AGR Description: Exhibits peptide-methionine (S)-S-oxide reductase activity; involved in aging; localizes to the mitochondrion; orthologous to human MSRA (methionine sulfoxide reductase A).
Merged Description: Exhibits peptide-methionine (S)-S-oxide reductase activity; involved in aging; localizes to the mitochondrion; orthologous to human MSRA (methionine sulfoxide reductase A); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC93315; mitochondrial peptide methionine sulfoxide reductase; peptide Met(O) reductase; peptide methionine sulfoxide reductase; peptide-methionine (S)-S-oxide reductase; PMSR; protein-methionine-S-oxide reductase
Orthologs:
Homo sapiens (human) : MSRA (methionine sulfoxide reductase A)  HGNC  Alliance
Mus musculus (house mouse) : Msra (methionine sulfoxide reductase A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Msra (methionine sulfoxide reductase A)
Pan paniscus (bonobo/pygmy chimpanzee) : MSRA (methionine sulfoxide reductase A)
Canis lupus familiaris (dog) : MSRA (methionine sulfoxide reductase A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Msra (methionine sulfoxide reductase A)
Sus scrofa (pig) : MSRA (methionine sulfoxide reductase A)
more info ...
Allele / Splice: Msraem3Mcwi   Msraem4Mcwi  
Genetic Models: SS-Msraem4Mcwi SS-Msraem3Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01547,488,333 - 47,800,662 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01551,307,920 - 51,550,758 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41543,509,775 - 43,756,283 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11543,543,986 - 43,771,983 (-)NCBI
Celera1538,127,708 - 38,353,451 (-)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Msra
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70979
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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