Strain Report - Rat Genome Database

Name: LE- Lrrk2 em1Sage
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain Registration

General

Strain: LE-Lrrk2^em1Sage

Symbol:

LE-Lrrk2^em1Sage

Strain:

LE-Lrrk2^em1

Substrain:

Sage

RGD ID:

7241050

Citation ID:

RRID:RGD_7241050

Ontology ID:

RS:0003385

Alleles:

Lrrk2^em1Sage

Previously known as:

LE-Lrrk2em1Sage

Type:

mutant

Source:

Horizon Discovery

Origin:

This strain was produced by injecting ZFNs into Crl:LE rat embryos. The resulting mutation is a 10-bp frameshift deletion in exon 30.

Last Known Status:

Live Animals (as of 2017-06-06)

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	122,826,696 - 122,987,711	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	7	132,857,311 - 133,018,549	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	7	132,531,591 - 132,694,226	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	7	130,105,902 - 130,267,747	RGD_MAPPER_PIPELINE	RGSC3.4

Mutant Strains

LE-Lrrk1em1SageLrrk2em1Sage

LE-Lrrk2em1Sage-/-

Annotation Click to see Annotation Detail View

References

References - curated

#	Reference Title	Reference Citation
1.	Data registered by Sigma Advanced Genetic Engineering Labs	Personal communication with SAGE Labs and RGD curators
2.	RGD Strain RSO annotation pipeline	RGD Automated Pipelines

Region

Additional Information

Nomenclature History

Date	Current Symbol	Previous Symbol	Description	Reference	Status
2014-04-03	LE-Lrrk2^em1Sage	LE-Lrrk2^em1Sage	Symbol updated	68687	APPROVED
2014-04-03	LE-Lrrk2^em1Sage	LE-Lrrk2^em1Sage	Name updated	68913	APPROVED
2014-04-03	LE-Lrrk2^em1Sage	LE-Lrrk2^em1Sage	Symbol updated	68687	APPROVED
2014-04-03	LE-Lrrk2^em1Sage	LE-Lrrk2^em1Sage	Name updated	68913	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: LE-Lrrk2em1Sage

Strain: LE-Lrrk2^em1Sage