Strain Report - Rat Genome Database

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Strain: SS-Sorcs2em4Mcwi

Symbol: SS-Sorcs2em4Mcwi
Strain: SS-Sorcs2em4M
Substrain: Mcwi
RGD ID: 5508363
Citation ID: RRID:RGD_5508363
Ontology ID: RS:0002926
Alleles: Sorcs2em4Mcwi
Also Known As: SS-Sorcs2em4Mcwi; SS-Sorcs2^[em4Mcwi]
Type: mutant
Available Source: Not Available
Origination: PhysGen Knockouts
Description: This strain was produced by injecting ZFNs targeting the sequence CACATCAGCTTCCGCTCTgactggGAGCTGGTCAAGGTGGAC into SS/JrHsdMcwi rat embryos. The resulting mutation is a 5-bp frameshift deletion in exon 15.
Last Known Status: Cryopreserved Sperm (as of 2017-01-26)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21474,711,199 - 74,711,203RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01479,538,911 - 79,912,333RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01479,176,694 - 79,547,823RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41479,968,072 - 80,344,330RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. PhysGen Knockouts PhysGen Knockout strains
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Sorcs2em4Mcwi-var1 chr14 74711199 74711203 GACTG - deletion mRatBN7.2

Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-26 SS-Sorcs2em4Mcwi    SS-Sorcs2em4Mcwi    Name updated 68913 APPROVED
2014-03-26 SS-Sorcs2em4Mcwi    SS-Sorcs2em4Mcwi    Symbol updated 68687 APPROVED
2014-03-26 SS-Sorcs2em4Mcwi    SS-Sorcs2em4Mcwi    Name updated 68913 APPROVED
2014-03-26 SS-Sorcs2em4Mcwi    SS-Sorcs2em4Mcwi    Symbol updated 68687 APPROVED
2013-08-14 SS-Sorcs2em4Mcwi    SS-Sorcs2em4Mcwi    Name updated 68913 APPROVED