Strain Report - Rat Genome Database

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Strain: SS-Sh2b3em1Mcwi-/+

Symbol: SS-Sh2b3em1Mcwi-/+
Strain: SS-Sh2b3em1-/Sh2b3em1+
Substrain: Mcwi
Full Name: SS-Sh2b3em1Mcwi-/Sh2b3em1Mcwi+
RGD ID: 5686322
Citation ID: RRID:RGD_5686322
Ontology ID: RS:0003031
Alleles: Sh2b3em1Mcwi
Also Known As: SS-Sh2b3em1Mcwi-/+; SS-Sh2b3em1Mcwi/2Mcwi; SS-Sh2b3em1Mcwi/2Mcwi; SS-Sh2b3em1Mcwi-/Sh2b3em1Mcwi+; SS-Sh2b3^[em1Mcwi-/+]
Type: mutant
Available Source: Not Available
Origination: PhysGen Knockouts
Description: ZFN mutant founders were backcrossed with SS/JrHsdMcwi to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders.
Genetic Status: Heterozygous
Last Known Status: Cryopreserved Sperm (as of 2021-11-03)
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21234,750,772 - 34,750,777RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01240,262,913 - 40,262,918RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01242,132,947 - 42,136,714RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41235,954,679 - 35,958,446RGD_MAPPER_PIPELINERGSC3.4


References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. PhysGen Knockouts PhysGen Knockout strains
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Sh2b3em1Mcwi-var1 chr12 34750772 34750777 CACTTG - deletion mRatBN7.2
Sh2b3em1Mcwi-var1 chr12 40262913 40262918 CACTTG - deletion Rnor_6.0

Additional Information

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-26 SS-Sh2b3em1Mcwi-/+  SS-Sh2b3em1Mcwi-/Sh2b3em1Mcwi+  SS-Sh2b3em1Mcwi-/+  SS-Sh2b3em1Mcwi-/Sh2b3em1Mcwi+  Symbol and/or name change 68913 APPROVED