Strain: F344-Aspaem31Kyo

Symbol: F344-Aspaem31Kyo
Strain: F344-Aspaem31
Substrain: Kyo
Ontology ID: RS:0004282
Alleles: Aspaem31Kyo
Also known as: Aspa KO (Line #31); NBRP Rat No: 0805; F344-Aspaem31Kyo
Type: mutant
Source: National BioResource Project for the Rat in Japan
Origin: The TALEN genome editing system was used to generate this mutant rat strain. The TALEN system caused a 14-bp deletion in the exon4 of Aspa gene, as a result created a premature stop codon in the gene. Decreased expression levels of Aspa gene and ASPA protein was observed. Histopatologically, this strain shows vacuole formation in the brain and spinal cord.
Coat Color: albino
Last Known Status: Cryopreserved Sperm (as of 2016-11-16)
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01059,839,693 - 59,888,244RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01059,578,788 - 59,627,450RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41060,178,509 - 60,199,207RGD_MAPPER_PIPELINERGSC3.4

Experimental Data Annotations
References - curated


Additional Information

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Strain Nomenclature
Strain Registration

RGD Object Information
RGD ID: 11564346
Created: 2016-11-16
Species: Rattus norvegicus
Last Modified: 2016-11-16
Status: ACTIVE