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Gene: Cp (ceruloplasmin) Rattus norvegicus
Symbol: Cp
Name: ceruloplasmin
Description: Exhibits copper ion binding activity. Involved in several processes, including animal organ development; response to copper ion; and response to nutrient. Localizes to anchored component of plasma membrane and extracellular space. Used to study brain edema and iron metabolism disease. Biomarker of Wilson disease; brain ischemia; heart disease; and hyperthyroidism. Human ortholog(s) of this gene implicated in aceruloplasminemia; epilepsy; and hemosiderosis. Orthologous to human CP (ceruloplasmin); PARTICIPATES IN hypoxia inducible factor pathway; iron efflux pathway; porphyrin and chlorophyll metabolic pathway; INTERACTS WITH (S)-colchicine; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,3,5-trinitro-1,3,5-triazinane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bilitranslocase; CERP; ceruloplasmin (ferroxidase); ferroxidase; RATCERP
Homo sapiens (human) : CP (ceruloplasmin)  HGNC  Alliance
Mus musculus (house mouse) : Cp (ceruloplasmin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cp (ceruloplasmin)
Pan paniscus (bonobo/pygmy chimpanzee) : CP (ceruloplasmin)
Canis lupus familiaris (dog) : CP (ceruloplasmin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cp (ceruloplasmin)
Sus scrofa (pig) : CP (ceruloplasmin)
Heterocephalus glaber (naked mole-rat) : Cp (ceruloplasmin)
more info ...
Allele / Splice: Cpem1Ang  
Genetic Models: SD-Cpem1Ang+/- SD-Cpem1Ang-/-
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02104,744,249 - 104,803,034 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2104,744,461 - 104,799,853 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02124,467,383 - 124,524,140 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42105,086,278 - 105,135,367 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12105,031,239 - 105,080,329 (+)NCBI
Celera297,809,748 - 97,868,604 (+)NCBICelera
Cytogenetic Map2q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cp
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2387
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.