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Gene: Cp (ceruloplasmin) Rattus norvegicus
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Symbol: Cp
Name: ceruloplasmin
Description: Exhibits copper ion binding activity. Involved in several processes, including aging; animal organ development; and response to copper ion. Localizes to the anchored component of plasma membrane and extracellular space. Used to study brain edema and iron metabolism disease. Biomarker of brain ischemia; heart disease; and hyperthyroidism. Human ortholog(s) of this gene implicated in aceruloplasminemia; epilepsy; and hemosiderosis. Orthologous to human CP (ceruloplasmin); PARTICIPATES IN hypoxia inducible factor pathway; iron efflux pathway; porphyrin and chlorophyll metabolic pathway; INTERACTS WITH (S)-colchicine; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,3,5-trinitro-1,3,5-triazinane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bilitranslocase; CERP; ceruloplasmin (ferroxidase); ferroxidase; RATCERP
Orthologs:
Homo sapiens (human) : CP (ceruloplasmin)  HGNC  Alliance
Mus musculus (house mouse) : Cp (ceruloplasmin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cp (ceruloplasmin)
Pan paniscus (bonobo/pygmy chimpanzee) : CP (ceruloplasmin)
Canis lupus familiaris (dog) : CP (ceruloplasmin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cp (ceruloplasmin)
Sus scrofa (pig) : CP (ceruloplasmin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02104,744,249 - 104,803,034 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02124,467,383 - 124,524,140 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42105,086,278 - 105,135,367 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12105,031,239 - 105,080,329 (+)NCBI
Celera297,809,748 - 97,868,604 (+)NCBICelera
Cytogenetic Map2q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cp
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2387
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-05-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.