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Gene: Cp (ceruloplasmin) Mus musculus
Symbol: Cp
Name: ceruloplasmin
Description: The protein encoded by this gene is a copper-containing glycoprotein found soluble in the serum and GPI-anchored in other tissues. It oxidizes Fe(II) to Fe(III) and is proposed to play an important role in iron homeostasis. In humans mutations of this gene cause aceruloplasminemia, which is characterized by retinal degeneration, diabetes, anemia and neurological symptoms. In mouse deficiency of this gene in combination with a deficiency of its homolog hephaestin causes retinal degeneration and serves as a pathophysiological model for aceruloplasminemia and age-related macular degeneration. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jan 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: D3Ertd555e; ferroxidase
Homo sapiens (human) : CP (ceruloplasmin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cp (ceruloplasmin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cp (ceruloplasmin)
Pan paniscus (bonobo/pygmy chimpanzee) : CP (ceruloplasmin)
Canis lupus familiaris (dog) : CP (ceruloplasmin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cp (ceruloplasmin)
Sus scrofa (pig) : CP (ceruloplasmin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38319,956,985 - 20,009,750 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37319,857,054 - 19,907,609 (+)NCBIGRCm37mm9NCBIm37
MGSCv36320,149,330 - 20,184,741 (+)NCBImm8
Celera319,946,245 - 19,999,014 (+)NCBICelera
Cytogenetic Map3 A2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cp
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10384
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-07-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.