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Gene: Fgl2 (fibrinogen-like 2) Rattus norvegicus
Symbol: Fgl2
Name: fibrinogen-like 2
Description: Predicted to have signaling receptor binding activity. Predicted to be involved in several processes, including T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; negative regulation of antigen processing and presentation; and negative regulation of immune effector process. Predicted to localize to collagen-containing extracellular matrix and extracellular space. Orthologous to human FGL2 (fibrinogen like 2); INTERACTS WITH 1,2,4-trimethylbenzene; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: fibroleukin
Homo sapiens (human) : FGL2 (fibrinogen like 2)  HGNC  Alliance
Mus musculus (house mouse) : Fgl2 (fibrinogen-like protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgl2 (fibrinogen like 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FGL2 (fibrinogen like 2)
Canis lupus familiaris (dog) : FGL2 (fibrinogen like 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgl2 (fibrinogen like 2)
Sus scrofa (pig) : FGL2 (fibrinogen like 2)
Chlorocebus sabaeus (African green monkey) : FGL2 (fibrinogen like 2)
Heterocephalus glaber (naked mole-rat) : Fgl2 (fibrinogen like 2)
more info ...
Allele / Splice: Fgl2m1Mcwi   Fgl2m2Mcwi   Fgl2m4Mcwi   Fgl2m3Mcwi  
Genetic Models: FHH-Fgl2m1Mcwi SS-Fgl2m4Mcwi SS-Fgl2m2Mcwi BN-Fgl2m3Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0410,323,598 - 10,329,241 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl410,323,607 - 10,329,241 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0410,315,666 - 10,321,309 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.449,176,333 - 9,181,976 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.149,178,562 - 9,181,975 (-)NCBI
Celera49,274,110 - 9,279,753 (-)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Fgl2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620170
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.