Gene: Fgl2 (fibrinogen-like 2) Rattus norvegicus
Symbol: Fgl2
Name: fibrinogen-like 2
Description: ENCODES a protein that exhibits peptidase activity (inferred); INVOLVED IN immunoglobulin production involved in immunoglobulin mediated immune response (inferred); negative regulation of defense response to virus (inferred); negative regulation of dendritic cell antigen processing and presentation (inferred); ASSOCIATED WITH allergic contact dermatitis (ortholog); Experimental Liver Cirrhosis (ortholog); pleomorphic xanthoastrocytoma (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2,4-trimethylbenzene; 1-naphthyl isothiocyanate
AGR Description: Predicted to have peptidase activity; predicted to be involved in parturition; orthologous to human FGL2 (fibrinogen like 2).
Merged Description: Predicted to have peptidase activity; predicted to be involved in parturition; orthologous to human FGL2 (fibrinogen like 2); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2,4-trimethylbenzene; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: fibroleukin
Homo sapiens (human) : FGL2 (fibrinogen like 2)  HGNC  Alliance
Mus musculus (house mouse) : Fgl2 (fibrinogen-like protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgl2 (fibrinogen like 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FGL2 (fibrinogen like 2)
Canis lupus familiaris (dog) : FGL2 (fibrinogen like 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgl2 (fibrinogen like 2)
Sus scrofa (pig) : FGL2 (fibrinogen like 2)
more info ...
Allele / Splice: Fgl2m1Mcwi   Fgl2m2Mcwi   Fgl2m4Mcwi   Fgl2m3Mcwi  
Genetic Models: FHH-Fgl2m1Mcwi SS-Fgl2m4Mcwi SS-Fgl2m2Mcwi BN-Fgl2m3Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0410,323,598 - 10,329,241 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0410,315,666 - 10,321,309 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.449,176,333 - 9,181,976 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.149,178,562 - 9,181,975 (-)NCBI
Celera49,274,110 - 9,279,753 (-)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Fgl2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620170
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.