Strain: F344-Aspaem34Kyo

Symbol: F344-Aspaem34Kyo
Strain: F344-Aspaem34
Substrain: Kyo
Ontology ID: RS:0004283
Alleles: Aspaem34Kyo
Also known as: NBRP Rat No: 0806; Aspa KO (Line #34)
Type: mutant
Source: National BioResource Project for the Rat in Japan
Origin: The TALEN genome editing system was used to generate this mutant rat strain. The TALEN system caused a 16-bp deletion in the exon4 of Aspa gene, as a result created a premature stop codon in the gene. Decreased expression levels of Aspa gene and ASPA protein was observed. Histopatologically, this strain shows vacuole formation in the brain and spinal cord.
Last Known Status: Cryopreserved Sperm (as of 2016-11-16)
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01059,839,693 - 59,888,244RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01059,578,788 - 59,627,450RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41060,178,509 - 60,199,207RGD_MAPPER_PIPELINERGSC3.4

Phenotype Annotations
Experimental Data Annotations
References - curated


Additional Information

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Strain Registration

RGD Object Information
RGD ID: 11564349
Created: 2016-11-16
Species: Rattus norvegicus
Last Modified: 2016-11-16
Status: ACTIVE