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Strain Registration

Strain: SD-Leprem2

Symbol: SD-Leprem2
Strain: SD-Leprem2
RGD ID: 12910517
Citation ID: RRID:RGD_12910517
Ontology ID: RS:0004467
Alleles: Leprem2
Also Known As: leprd1/d1; SD-Leprem2; SD-Lepr^[em2]
Type: mutant
Available Source: Not Available
Origination: East China Normal University, Shanghai, China
Description: This strain was produced by injecting TALEN targeting the sequence of rat Lepr into SD embryos. The resulting mutation is a 1-bp deletion.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25116,372,431 - 116,372,431RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.05120,581,486 - 120,581,486RGD_MAPPER_PIPELINERnor6.0
Rnor_5.05124,380,327 - 124,556,585RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.45122,320,075 - 122,503,449RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View
obesity  (IMP)


References

References - curated
# Reference Title Reference Citation
1. Generation of obese rat model by transcription activator-like effector nucleases targeting the leptin receptor gene. Chen Y, etal., Sci China Life Sci. 2017 Feb;60(2):152-157. doi: 10.1007/s11427-016-5049-y. Epub 2016 May 25.

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Leprem2-var1 chr5 116372431 116372431 G - deletion mRatBN7.2
Leprem2-var1 chr5 120581486 120581486 G - deletion Rnor_6.0

Additional Information