Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Grm2 (glutamate metabotropic receptor 2) Rattus norvegicus
Analyze
Symbol: Grm2
Name: glutamate metabotropic receptor 2
RGD ID: 2743
Description: Exhibits group II metabotropic glutamate receptor activity and scaffold protein binding activity. Involved in several processes, including behavioral response to nicotine; glutamate secretion; and regulation of amine transport. Localizes to astrocyte projection; axon; and presynaptic membrane. Used to study heroin dependence. Orthologous to human GRM2 (glutamate metabotropic receptor 2); PARTICIPATES IN glutamate signaling pathway; INTERACTS WITH (+)-pilocarpine; (S)-nicotine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glutamate receptor, metabotropic 2; metabotropic glutamate receptor 2; mGluR2
Orthologs:
Homo sapiens (human) : GRM2 (glutamate metabotropic receptor 2)  HGNC  Alliance
Mus musculus (house mouse) : Grm2 (glutamate receptor, metabotropic 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grm2 (glutamate metabotropic receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GRM2 (glutamate metabotropic receptor 2)
Canis lupus familiaris (dog) : GRM2 (glutamate metabotropic receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grm2 (glutamate metabotropic receptor 2)
Sus scrofa (pig) : GRM2 (glutamate metabotropic receptor 2)
Chlorocebus sabaeus (African green monkey) : GRM2 (glutamate metabotropic receptor 2)
Heterocephalus glaber (naked mole-rat) : Grm2 (glutamate metabotropic receptor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08115,344,999 - 115,358,628 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8115,344,999 - 115,358,046 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08114,705,123 - 114,718,193 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48111,837,086 - 111,850,133 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18111,857,819 - 111,869,581 (-)NCBI
Celera8106,592,051 - 106,605,096 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Grm2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2743
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-09-01
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.