Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Wwox (WW domain-containing oxidoreductase) Rattus norvegicus
Analyze
Symbol: Wwox
Name: WW domain-containing oxidoreductase
Description: Predicted to have enzyme binding activity; transcription coactivator activity; and transcription corepressor activity. Predicted to be involved in several processes, including apoptotic signaling pathway; hippo signaling; and regulation of signal transduction. Predicted to colocalize with microvillus and plasma membrane. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; early infantile epileptic encephalopathy 28; esophageal cancer; esophagus squamous cell carcinoma; and squamous cell carcinoma. Orthologous to human WWOX (WW domain containing oxidoreductase); INTERACTS WITH (+)-schisandrin B; acrylamide; aflatoxin B1.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC292041
Orthologs:
Homo sapiens (human) : WWOX (WW domain containing oxidoreductase)  HGNC  Alliance
Mus musculus (house mouse) : Wwox (WW domain-containing oxidoreductase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wwox (WW domain containing oxidoreductase)
Pan paniscus (bonobo/pygmy chimpanzee) : WWOX (WW domain containing oxidoreductase)
Canis lupus familiaris (dog) : WWOX (WW domain containing oxidoreductase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wwox (WW domain containing oxidoreductase)
Sus scrofa (pig) : WWOX (WW domain containing oxidoreductase)
Chlorocebus sabaeus (African green monkey) : WWOX (WW domain containing oxidoreductase)
Heterocephalus glaber (naked mole-rat) : Wwox (WW domain containing oxidoreductase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01946,761,353 - 47,695,247 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01957,582,172 - 58,503,008 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41944,516,391 - 44,829,849 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11944,521,372 - 44,611,040 (+)NCBI
Celera1941,740,658 - 42,034,912 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Wwox
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309927
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-01-07
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.