Gene: Fyn (FYN proto-oncogene, Src family tyrosine kinase) Rattus norvegicus
Symbol: Fyn
Name: FYN proto-oncogene, Src family tyrosine kinase
Description: ENCODES a protein that exhibits CD4 receptor binding; CD8 receptor binding; enzyme binding; INVOLVED IN cellular response to growth factor stimulus; cellular response to peptide hormone stimulus; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; PARTICIPATES IN altered Reelin signaling pathway; E-cadherin signaling pathway; eicosanoid signaling pathway; ASSOCIATED WITH Burns; Epilepsy, Temporal Lobe; Sepsis; FOUND IN intracellular membrane-bounded organelle; membrane; mitochondrion; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 2-arachidonoylglycerol
Type: protein-coding
Also known as: FYN oncogene related to SRC, FGR, YES; fyn proto-oncogene; p59-Fyn; proto-oncogene c-Fyn; proto-oncogene tyrosine-protein kinase Fyn; tyrosine-protein kinase Fyn
Homo sapiens (human) : FYN (FYN proto-oncogene, Src family tyrosine kinase)  HGNC  AGR
Mus musculus (house mouse) : Fyn (Fyn proto-oncogene)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Fyn (FYN proto-oncogene, Src family tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : FYN (FYN proto-oncogene, Src family tyrosine kinase)
Canis lupus familiaris (dog) : FYN (FYN proto-oncogene, Src family tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fyn (FYN proto-oncogene, Src family tyrosine kinase)
more info ...
Allele / Splice: Fynem6Mcwi   Fynem1Mcwi  
Genetic Models: SS-Fynem6Mcwi SS-Fynem1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02044,436,354 - 44,630,316 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02046,160,734 - 46,353,456 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42043,501,853 - 43,695,567 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12043,524,863 - 43,718,578 (+)NCBI
Celera2043,482,980 - 43,675,123 (+)NCBICelera
Cytogenetic Map20q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Fyn
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2641
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-11-28
Status: ACTIVE