Gene: Cd4 (Cd4 molecule) Rattus norvegicus
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Symbol: Cd4
Name: Cd4 molecule
Description: ENCODES a protein that exhibits immunoglobulin binding; protein kinase binding; protein tyrosine kinase binding; INVOLVED IN positive regulation of calcium ion transport into cytosol; positive regulation of T cell proliferation; response to estradiol; PARTICIPATES IN Arf family mediated signaling pathway; interleukin-12 signaling pathway; interleukin-23 signaling pathway; ASSOCIATED WITH Corneal Graft Rejection; Experimental Arthritis; Experimental Autoimmune Encephalomyelitis; FOUND IN external side of plasma membrane; plasma membrane; cell surface (ortholog); INTERACTS WITH ammonium chloride; bisphenol A; dichlorine
AGR Description: Exhibits immunoglobulin binding activity, protein tyrosine kinase binding activity, and signaling receptor binding activity; involved in several processes, including T cell activation, positive regulation of T cell proliferation, and positive regulation of calcium ion transport into cytosol; localizes to the external side of plasma membrane; used to study septic arthritis and sialadenitis; orthologous to human CD4 (CD4 molecule).
Merged Description: Exhibits immunoglobulin binding activity, protein tyrosine kinase binding activity, and signaling receptor binding activity; involved in several processes, including T cell activation, positive regulation of T cell proliferation, and positive regulation of calcium ion transport into cytosol; localizes to the external side of plasma membrane; used to study septic arthritis and sialadenitis; orthologous to human CD4 (CD4 molecule); PARTICIPATES IN Arf family mediated signaling pathway; interleukin-12 signaling pathway; interleukin-23 signaling pathway; INTERACTS WITH ammonium chloride; bisphenol A; dichlorine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CD4 antigen; CD4 antigen (p55); p55; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; W3/25; W3/25 antigen
Orthologs:
Homo sapiens (human) : CD4 (CD4 molecule)  HGNC  Alliance
Mus musculus (house mouse) : Cd4 (CD4 antigen)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd4 (CD4 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD4 (CD4 molecule)
Canis lupus familiaris (dog) : CD4 (CD4 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd4 (CD4 molecule)
Sus scrofa (pig) : CD4 (CD4 molecule)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04157,381,862 - 157,408,357 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04224,399,640 - 224,426,134 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,988,512 - 161,014,038 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14161,250,744 - 161,258,974 (-)NCBI
Celera4146,407,680 - 146,432,465 (-)NCBICelera
Cytogenetic Map4q42NCBI
RH 3.4 Map41003.4RGD
JBrowse: View Region in Genome Browser (JBrowse)
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Genomics

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QTLs in Region (Rnor_6.0)
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Sequence

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Strain Sequence Variants (Rnor 5.0)

Additional Information

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Nomenclature History
RGD Curation Notes
  
More on Cd4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2306
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.