Gene: Cd4 (Cd4 molecule) Rattus norvegicus
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Symbol: Cd4
Name: Cd4 molecule
Description: ENCODES a protein that exhibits immunoglobulin binding; protein kinase binding; protein tyrosine kinase binding; INVOLVED IN positive regulation of calcium ion transport into cytosol; positive regulation of T cell proliferation; response to estradiol; PARTICIPATES IN Arf family mediated signaling pathway; interleukin-12 signaling pathway; interleukin-23 signaling pathway; ASSOCIATED WITH Corneal Graft Rejection; Experimental Arthritis; Experimental Autoimmune Encephalomyelitis; FOUND IN external side of plasma membrane; plasma membrane; cell surface (ortholog); INTERACTS WITH ammonium chloride; bisphenol A; dichlorine
AGR Description: Exhibits immunoglobulin binding activity, protein tyrosine kinase binding activity, and signaling receptor binding activity; involved in several processes, including T cell activation, positive regulation of T cell proliferation, and positive regulation of calcium ion transport into cytosol; localizes to the external side of plasma membrane; used to study septic arthritis and sialadenitis; orthologous to human CD4 (CD4 molecule).
Merged Description: Exhibits immunoglobulin binding activity, protein tyrosine kinase binding activity, and signaling receptor binding activity; involved in several processes, including T cell activation, positive regulation of T cell proliferation, and positive regulation of calcium ion transport into cytosol; localizes to the external side of plasma membrane; used to study septic arthritis and sialadenitis; orthologous to human CD4 (CD4 molecule); PARTICIPATES IN Arf family mediated signaling pathway; interleukin-12 signaling pathway; interleukin-23 signaling pathway; INTERACTS WITH ammonium chloride; bisphenol A; dichlorine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CD4 antigen; CD4 antigen (p55); p55; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; W3/25; W3/25 antigen
Orthologs:
Homo sapiens (human) : CD4 (CD4 molecule)  HGNC  Alliance
Mus musculus (house mouse) : Cd4 (CD4 antigen)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd4 (CD4 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD4 (CD4 molecule)
Canis lupus familiaris (dog) : CD4 (CD4 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd4 (CD4 molecule)
Sus scrofa (pig) : CD4 (CD4 molecule)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04157,381,862 - 157,408,357 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04224,399,640 - 224,426,134 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,988,512 - 161,014,038 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14161,250,744 - 161,258,974 (-)NCBI
Celera4146,407,680 - 146,432,465 (-)NCBICelera
Cytogenetic Map4q42NCBI
RH 3.4 Map41003.4RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cd4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2306
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.