Gene: FYN (FYN proto-oncogene, Src family tyrosine kinase) Chlorocebus sabaeus

Analyze

Symbol:

FYN

Name:

FYN proto-oncogene, Src family tyrosine kinase

RGD ID:

18356632

Description:

ENCODES a protein that exhibits CD4 receptor binding (ortholog); CD8 receptor binding (ortholog); enzyme binding (ortholog); INVOLVED IN activated T cell proliferation (ortholog); cell surface receptor signaling pathway (ortholog); cellular response to glycine (ortholog); PARTICIPATES IN altered Reelin signaling pathway; E-cadherin signaling pathway; eicosanoid signaling pathway; ASSOCIATED WITH adult T-cell leukemia/lymphoma (ortholog); alcohol dependence (ortholog); Alzheimer's disease (ortholog); FOUND IN cytoplasm (ortholog); glutamatergic synapse (ortholog); membrane raft (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

tyrosine-protein kinase Fyn

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mChlSab1.0.hap1	13	35,844,515 - 36,051,997 (-)	NCBI		mChlSab1.0.hap1
Vero_WHO_p1.0	NW_023666040	34,319,593 - 34,528,593 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0
ChlSab1.1	13	61,988,265 - 62,218,756 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	62,159,874 - 62,219,672 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

adult T-cell leukemia/lymphoma (ISO)

alcohol dependence (ISO)

Alzheimer's disease (ISO)

asthma (ISO)

Breast Cancer, Familial (ISO)

Burns (ISO)

Catalepsy (ISO)

Cocaine-Related Disorders (ISO)

colon adenocarcinoma (ISO)

Experimental Liver Cirrhosis (ISO)

Familial Pancreatic Carcinoma (ISO)

melanoma (ISO)

morphine withdrawal syndrome (ISO)

ovarian serous cystadenocarcinoma (ISO)

peripheral T-cell lymphoma (ISO)

primary ovarian insufficiency (ISO)

pulmonary fibrosis (ISO)

sarcoma (ISO)

schizophrenia (ISO)

Sepsis (ISO)

skin disease (ISO)

skin squamous cell carcinoma (ISO)

Stomach Neoplasms (ISO)

temporal lobe epilepsy (ISO)

Thyroid Carcinoma, Nonmedullary 1 (ISO)

urinary bladder cancer (ISO)

uterine corpus endometrial carcinoma (ISO)

uveal melanoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

activated T cell proliferation (ISO)

cell surface receptor signaling pathway (ISO)

cellular response to amyloid-beta (IEA)

cellular response to glycine (ISO)

cellular response to growth factor stimulus (ISO)

cellular response to hydrogen peroxide (ISO)

cellular response to L-glutamate (ISO)

cellular response to peptide hormone stimulus (ISO)

cellular response to platelet-derived growth factor stimulus (ISO)

cellular response to transforming growth factor beta stimulus (ISO)

dendrite morphogenesis (ISO)

detection of mechanical stimulus involved in sensory perception of pain (ISO)

Fc-gamma receptor signaling pathway involved in phagocytosis (IEA)

forebrain development (ISO)

G protein-coupled glutamate receptor signaling pathway (IEA)

gene expression (ISO)

heart process (IEA)

intracellular signal transduction (IEA)

modulation of chemical synaptic transmission (IEA)

natural killer cell activation (IEA)

negative regulation of angiogenesis (IEA)

negative regulation of dendritic spine maintenance (IEA)

negative regulation of extrinsic apoptotic signaling pathway in absence of ligand (ISO)

negative regulation of gene expression (IEA)

negative regulation of hydrogen peroxide biosynthetic process (ISO)

negative regulation of inflammatory response to antigenic stimulus (IEA)

negative regulation of neuron apoptotic process (ISO)

negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway (ISO)

negative regulation of protein catabolic process (ISO)

negative regulation of protein ubiquitination (ISO)

negative regulation of T cell activation (IEA)

negative regulation of T cell receptor signaling pathway (IEA)

neuron migration (ISO)

peptidyl-tyrosine phosphorylation (ISO)

positive regulation of neuron projection development (ISO)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ISO)

positive regulation of protein localization to nucleus (ISO)

positive regulation of protein targeting to membrane (IEA)

positive regulation of tyrosine phosphorylation of STAT protein (ISO)

protein autophosphorylation (ISO)

protein phosphorylation (ISO)

reelin-mediated signaling pathway (IEA)

regulation of calcium ion import across plasma membrane (IEA)

regulation of cell shape (ISO)

regulation of glutamate receptor signaling pathway (IEA)

response to amyloid-beta (IEA)

response to cocaine (ISO)

response to ethanol (ISO)

response to singlet oxygen (ISO)

response to xenobiotic stimulus (ISO)

T cell receptor signaling pathway (IEA)

Cellular Component

actin filament (IEA)

cell body (IEA)

cell periphery (IEA)

cytoplasm (ISO)

cytosol (IEA)

dendrite (IEA)

endosome (IEA)

glial cell projection (IEA)

glutamatergic synapse (ISO)

membrane raft (IEA,ISO)

mitochondrion (ISO)

nucleus (ISO)

perikaryon (ISO)

perinuclear endoplasmic reticulum (ISO)

perinuclear region of cytoplasm (ISO)

plasma membrane (IEA)

postsynaptic density (IEA)

postsynaptic density, intracellular component (ISO)

Schaffer collateral - CA1 synapse (IEA)

Molecular Function

alpha-tubulin binding (IEA)

ATP binding (IEA)

CD4 receptor binding (ISO)

CD8 receptor binding (ISO)

disordered domain specific binding (IEA)

enzyme binding (IEA,ISO)

ephrin receptor binding (IEA)

G protein-coupled receptor binding (IEA)

growth factor receptor binding (IEA)

identical protein binding (IEA)

kinase activity (IEA)

non-membrane spanning protein tyrosine kinase activity (IEA)

nucleotide binding (IEA)

peptide hormone receptor binding (ISO)

phosphatidylinositol 3-kinase binding (ISO)

phospholipase activator activity (IEA)

phospholipase binding (IEA)

protein binding (ISO)

protein kinase activity (IEA,ISO)

protein tyrosine kinase activity (IEA,ISO)

protein-containing complex binding (ISO)

scaffold protein binding (IEA)

signaling receptor binding (ISO)

T cell receptor binding (ISO)

tau protein binding (IEA)

transferase activity (IEA)

transmembrane transporter binding (IEA)

tubulin binding (IEA)

type 5 metabotropic glutamate receptor binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

altered Reelin signaling pathway (ISO)

E-cadherin signaling pathway (ISO)

eicosanoid signaling pathway (ISO)

ephrin - ephrin receptor bidirectional signaling axis (ISO)

Fc epsilon receptor mediated signaling pathway (ISO)

glypican signaling pathway (ISO)

interleukin-2 signaling pathway (ISO)

phosphatidylinositol 3-kinase class I signaling pathway (ISO)

platelet-derived growth factor signaling pathway (ISO)

protein kinase C (PKC) signaling pathway (ISO)

Reelin signaling pathway (ISO)

syndecan signaling pathway (ISO)

vascular endothelial growth factor signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

FYN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mChlSab1.0.hap1	13	35,844,515 - 36,051,997 (-)	NCBI		mChlSab1.0.hap1
Vero_WHO_p1.0	NW_023666040	34,319,593 - 34,528,593 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0
ChlSab1.1	13	61,988,265 - 62,218,756 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	62,159,874 - 62,219,672 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM

FYN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	111,660,332 - 111,873,452 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	111,660,332 - 111,873,479 (-)	Ensembl		GRCh38.p14 Ensembl	hg38	GRCh38
GRCh37	6	111,981,535 - 112,194,655 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	112,089,178 - 112,301,320 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	6	112,089,179 - 112,186,978	NCBI
Celera	6	112,729,071 - 112,941,209 (-)	NCBI		Celera
Cytogenetic Map	6	q21	NCBI
HuRef	6	109,554,123 - 109,767,060 (-)	NCBI		HuRef
CHM1_1	6	112,244,349 - 112,457,405 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	112,843,350 - 113,056,537 (-)	NCBI		T2T-CHM13v2.0

Fyn
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	39,245,735 - 39,441,377 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	39,244,851 - 39,442,227 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	39,369,743 - 39,565,381 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	39,368,855 - 39,565,381 (+)	Ensembl		GRCm38.p6 Ensembl	mm10	GRCm38
MGSCv37	10	39,089,605 - 39,285,187 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	39,059,502 - 39,254,797 (+)	NCBI		MGSCv36	mm8
Celera	10	40,254,667 - 40,450,960 (+)	NCBI		Celera
Cytogenetic Map	10	B1	NCBI
cM Map	10	20.51	NCBI

Fyn
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	44,322,635 - 44,514,498 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	20	44,322,361 - 44,515,479 (+)	Ensembl				GRCr8
mRatBN7.2	20	42,767,733 - 42,960,903 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	42,766,369 - 42,959,911 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	20	44,517,354 - 44,708,655 (+)	NCBI	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	44,176,580 - 44,367,880 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	44,909,156 - 45,110,016 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	20	44,358,973 - 44,554,852 (+)	NCBI
Lyon_Normotensive	20	45,425,474 - 45,621,350 (+)	NCBI
Lyon_Hypertensive	20	45,488,448 - 45,684,319 (+)	NCBI
F344_StmMcwi	20	44,310,038 - 44,505,899 (+)	NCBI
Rnor_6.0	20	44,436,354 - 44,630,316 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	44,436,403 - 44,630,317 (+)	Ensembl		Rnor_6.0 Ensembl	rn6	Rnor6.0
Rnor_5.0	20	46,160,734 - 46,353,456 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	20	43,501,853 - 43,695,567 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	20	43,482,980 - 43,675,123 (+)	NCBI		Celera
RGSC_v3.1	20	43,524,863 - 43,718,578 (+)	NCBI
Cytogenetic Map	20	q12	NCBI

Fyn
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955411	36,401,842 - 36,512,054 (-)	Ensembl		ChiLan1.0 Ensembl
ChiLan1.0	NW_004955411	36,403,156 - 36,597,660 (-)	NCBI	ChiLan1.0	ChiLan1.0

FYN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	131,675,357 - 131,889,692 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	129,561,361 - 129,775,652 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	109,469,750 - 109,684,086 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	113,545,944 - 113,732,893 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	113,545,944 - 113,604,451 (-)	Ensembl		PanPan1.1 Ensembl	panPan2	panpan1.1

FYN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	68,105,060 - 68,316,630 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	68,075,184 - 68,316,541 (-)	Ensembl		CanFam3.1 Ensembl	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	67,924,675 - 68,136,151 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	68,986,784 - 69,198,525 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	68,987,778 - 69,174,188 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	68,338,226 - 68,549,311 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	68,184,783 - 68,396,306 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	68,510,644 - 68,722,405 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Fyn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mIctTri1.hap1	8	50,392,882 - 50,593,149 (+)	NCBI		mIctTri1.hap1
HiC_Itri_2	NW_024404946	103,155,533 - 103,356,140 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936679	387,387 - 443,880 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936679	388,500 - 588,518 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FYN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	77,585,439 - 77,810,581 (-)	Ensembl		Sscrofa11.1 Ensembl	susScr11	Sscrofa11.1
Sscrofa11.1	1	77,584,675 - 77,810,605 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	87,249,062 - 87,253,260 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Sscrofa10.2	1	87,146,809 - 87,191,215 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Pig Cytomap	1	p13	NCBI

Fyn
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624933	248,298 - 456,933 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2
HetGla_female_1.0 Ensembl	NW_004624933	389,627 - 456,520 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl	1	19,535,873 - 19,749,549 (-)	Ensembl

Fyn
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	18	39,161,813 - 39,369,515 (+)	NCBI	Rrattus_CSIRO_v1	Rrattus_CSIRO_v1

Variants

Variants in FYN
4131 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
76	36	20	36	36	60	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008007305	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008007306	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008007307	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008007308	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008007309	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008007310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008007311	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008007312	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038001005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038001006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_073022418	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_073022419	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_073022420	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JBLKOC010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000013686 ⟹ ENSCSAP00000011676

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	13	62,159,874 - 62,219,672 (+)	Ensembl

RefSeq Acc Id:

XM_008007307 ⟹ XP_008005498

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
mChlSab1.0.hap1	13	35,844,515 - 36,051,997 (-)	NCBI
Vero_WHO_p1.0	NW_023666040	34,319,593 - 34,527,658 (+)	NCBI
ChlSab1.1	13	61,988,290 - 62,218,753 (+)	NCBI

Sequence:

show sequence

GCGGTGGTGGCGGCGGCGCGTCGTTGCAGTTGCGCCATCTGTCAGGAGCGGAGCCGGCGAGGAG
GGGGCTGCCGCGGGCGAGGAGGAGGGGTCGCCGCGAGCCGAAGGCCTTCGAGACCCGCCCGCCG
GCCGGCGGCGAGAGTAGAGGCGAGGTTGCCCTGCGAGCGGCGCGTCCTCTCCCACCCGGGCGCG
CCGCGCTTCTCCCGGCGCACCGAGGACCGCCCGGGCGCACACAAAGCCGCCGCCCGCGTCGCAC
CGCCCGGCGGCCGCCGCCCGCGCCAGGGAGGGATCCGGCCGCCGGGCCGGGGACACCCCGGCGC
CGCCCCCTCCGTGCTCTCGGAAGGCCCACCGGCTCCTGGGCCCGCCGGGGAGCTCCCGGAGCCG
CCTCGGCCGCGCCGGAGGAGGGCGGGGAGAGGACCATGTGAATGGGCTCCGGAGCCTGAGCGCC
GCGCAGGACCAGTCCTGCCGCTGTTGTAGAAGACATGTGGTGTATATAAAGTTTGTGATCGTTG
GCGGAAATTCTGGAATTTAGATAATGGGCTGTGTGCAATGTAAGGATAAAGAAGCAACAAAACT
GACGGAGGAGAGGGACGGCAGCCTGAACCAGAGCTCCGGGTACCGCTATGGCACAGACCCCACC
CCTCAGCACTACCCCAGCTTCGGTGTGACCTCCATCCCCAACTACAACAACTTCCACGCAGCCG
GGGGCCAAGGACTCACTGTCTTTGGAGGTGTGAACTCTTCGTCTCATACGGGGACCTTGCGTAC
GAGAGGAGGAACAGGAGTGACACTGTTTGTGGCCCTTTATGACTATGAAGCACGGACGGAAGAT
GACCTGAGTTTTCACAAAGGAGAAAAATTTCAAATATTGAACAGCTCGGAAGGAGATTGGTGGG
AAGCCCGCTCCTTGACAACTGGAGAGACAGGTTACATTCCCAGCAATTATGTGGCTCCAGTGGA
CTCTATCCAGGCAGAAGAGTGGTACTTTGGAAAACTTGGCCGAAAAGATGCTGAGCGACAGCTA
TTGTCCTTTGGAAACCCAAGAGGTACCTTTCTTATCCGCGAGAGTGAAACCACCAAAGGTGCCT
ATTCACTTTCCATCCGCGATTGGGATGATATGAAAGGAGACCACGTCAAACATTATAAAATTCG
CAAACTTGACAACGGTGGATACTACATTACCACCCGGGCCCAGTTTGAAACCCTTCAGCAGCTT
GTACAACATTACTCAGAGAGAGCTGCAGGTCTCTGCTGCCGCCTAGTAGTTCCCTGTCACAAAG
GGATGCCAAGGCTTACCGATCTGTCTGTCAAAACCAAAGATGTCTGGGAAATCCCTCGAGAATC
CCTGCAGTTGATCAAGAGACTGGGAAATGGGCAGTTTGGGGAAGTATGGATGGGTACCTGGAAT
GGAAACACAAAAGTAGCCATAAAGACTCTTAAACCAGGCACAATGTCCCCCGAATCATTCCTTG
AGGAAGCGCAGATCATGAAGAAGCTGAAGCACGACAAGCTGGTCCAGCTCTACGCAGTGGTGTC
TGAGGAGCCCATCTACATCGTCACCGAGTATATGAATAAAGGAAGTTTACTGGATTTCTTAAAA
GATGGAGAAGGAAGAGCTCTGAAATTACCAAATCTTGTGGACATGGCAGCACAGGTGGCTGCAG
GAATGGCTTACATCGAGCGCATGAATTATATCCATAGAGATCTGCGATCAGCAAACATTCTAGT
GGGGAATGGACTCATATGCAAGATTGCTGATTTCGGATTGGCCCGATTGATCGAAGACAATGAG
TACACAGCAAGACAAGGTGCAAAATTCCCCATCAAGTGGACGGCCCCCGAGGCAGCCCTGTACG
GGAGGTTCACAATCAAGTCTGACGTGTGGTCTTTTGGAATCTTACTCACAGAGCTGGTCACCAA
AGGAAGAGTGCCATACCCAGGCATGAACAACCGGGAGGTGCTGGAGCAGGTGGAGCGAGGCTAC
AGGATGCCGTGCCCGCAGGACTGCCCCATCTCTCTGCATGAGCTCATGATCCACTGCTGGAAAA
AGGACCCTGAAGAACGCCCCACTTTTGAGTACTTGCAGAGCTTCCTGGAAGACTACTTTACCGC
CACAGAGCCCCAGTACCAACCTGGTGAAAACCTGTAAGGCCCGGGTCTGCCTGCGGAGAGAGGC
CTTGTCCCAGAGGCTGCCCCACCCCTCCCCATTAGCTTTCAATTCCGTAGCCGGCTGCTCCCCA
GCAGCAGAACCGCCCAGGATCAGATTGCATGTGACTCTGAAGCTGACGAACTTCCATGGCCCTC
ATTAATGACACTTGTCCCCAAATCCGAACCTCCTCTGTGAAGCATTCGAGACAGAACCTTGTTA
TTTCTCAGACTTTGGAAAATGCATTGTATCGATGTTATGTAAAAGGCCAAACCTCTGTTCAGTG
TAAATAGTTACTCCAGTGCCAACAATCCTAGTGCTTTCCTTTTTTAAAAATGCAAATCCTATGT
GATTTTAACTCTGTCTTCACCTGATTCAACTAAAAAAAAAAAGTATTATTTTCCAAAAGTGGCC
TCTTTGTCTAAAACAATAAAATTTTTTTTCATGTTTTAACAAAAACCAATCA

hide sequence

RefSeq Acc Id:

XM_008007309 ⟹ XP_008005500

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
mChlSab1.0.hap1	13	35,844,515 - 35,940,209 (-)	NCBI
Vero_WHO_p1.0	NW_023666040	34,430,824 - 34,528,593 (+)	NCBI
ChlSab1.1	13	62,121,351 - 62,218,756 (+)	NCBI

Sequence:

show sequence

TGGCTGGAGAGTGTGTGAGGGGCAGTGGGAGATTGGTGGAAAAAATATAGGCCACTGGTGTTGA
AGGCTGGGAGGCCACGCTTCAGAGCGGAGAAAGTTGCTAATCAGAGAAGCGACATTCTGGAGGT
GGAATTTAGATAATGGGCTGTGTGCAATGTAAGGATAAAGAAGCAACAAAACTGACGGAGGAGA
GGGACGGCAGCCTGAACCAGAGCTCCGGGTACCGCTATGGCACAGACCCCACCCCTCAGCACTA
CCCCAGCTTCGGTGTGACCTCCATCCCCAACTACAACAACTTCCACGCAGCCGGGGGCCAAGGA
CTCACTGTCTTTGGAGGTGTGAACTCTTCGTCTCATACGGGGACCTTGCGTACGAGAGGAGGAA
CAGGAGTGACACTGTTTGTGGCCCTTTATGACTATGAAGCACGGACGGAAGATGACCTGAGTTT
TCACAAAGGAGAAAAATTTCAAATATTGAACAGCTCGGAAGGAGATTGGTGGGAAGCCCGCTCC
TTGACAACTGGAGAGACAGGTTACATTCCCAGCAATTATGTGGCTCCAGTGGACTCTATCCAGG
CAGAAGAGTGGTACTTTGGAAAACTTGGCCGAAAAGATGCTGAGCGACAGCTATTGTCCTTTGG
AAACCCAAGAGGTACCTTTCTTATCCGCGAGAGTGAAACCACCAAAGGTGCCTATTCACTTTCC
ATCCGCGATTGGGATGATATGAAAGGAGACCACGTCAAACATTATAAAATTCGCAAACTTGACA
ACGGTGGATACTACATTACCACCCGGGCCCAGTTTGAAACCCTTCAGCAGCTTGTACAACATTA
CTCAGAGAGAGCTGCAGGTCTCTGCTGCCGCCTAGTAGTTCCCTGTCACAAAGGGATGCCAAGG
CTTACCGATCTGTCTGTCAAAACCAAAGATGTCTGGGAAATCCCTCGAGAATCCCTGCAGTTGA
TCAAGAGACTGGGAAATGGGCAGTTTGGGGAAGTATGGATGGGTACCTGGAATGGAAACACAAA
AGTAGCCATAAAGACTCTTAAACCAGGCACAATGTCCCCCGAATCATTCCTTGAGGAAGCGCAG
ATCATGAAGAAGCTGAAGCACGACAAGCTGGTCCAGCTCTACGCAGTGGTGTCTGAGGAGCCCA
TCTACATCGTCACCGAGTATATGAATAAAGGAAGTTTACTGGATTTCTTAAAAGATGGAGAAGG
AAGAGCTCTGAAATTACCAAATCTTGTGGACATGGCAGCACAGGTGGCTGCAGGAATGGCTTAC
ATCGAGCGCATGAATTATATCCATAGAGATCTGCGATCAGCAAACATTCTAGTGGGGAATGGAC
TCATATGCAAGATTGCTGATTTCGGATTGGCCCGATTGATCGAAGACAATGAGTACACAGCAAG
ACAAGGTGCAAAATTCCCCATCAAGTGGACGGCCCCCGAGGCAGCCCTGTACGGGAGGTTCACA
ATCAAGTCTGACGTGTGGTCTTTTGGAATCTTACTCACAGAGCTGGTCACCAAAGGAAGAGTGC
CATACCCAGGCATGAACAACCGGGAGGTGCTGGAGCAGGTGGAGCGAGGCTACAGGATGCCGTG
CCCGCAGGACTGCCCCATCTCTCTGCATGAGCTCATGATCCACTGCTGGAAAAAGGACCCTGAA
GAACGCCCCACTTTTGAGTACTTGCAGAGCTTCCTGGAAGACTACTTTACCGCCACAGAGCCCC
AGTACCAACCTGGTGAAAACCTGTAAGGCCCGGGTCTGCCTGCGGAGAGAGGCCTTGTCCCAGA
GGCTGCCCCACCCCTCCCCATTAGCTTTCAATTCCGTAGCCGGCTGCTCCCCAGCAGCAGAACC
GCCCAGGATCAGATTGCATGTGACTCTGAAGCTGACGAACTTCCATGGCCCTCATTAATGACAC
TTGTCCCCAAATCCGAACCTCCTCTGTGAAGCATTCGAGACAGAACCTTGTTATTTCTCAGACT
TTGGAAAATGCATTGTATCGATGTTATGTAAAAGGCCAAACCTCTGTTCAGTGTAAATAGTTAC
TCCAGTGCCAACAATCCTAGTGCTTTCCTTTTTTAAAAATGCAAATCCTATGTGATTTTAACTC
TGTCTTCACCTGATTCAACTAAAAAAAAAAAGTATTATTTTCCAAAAGTGGCCTCTTTGTCTAA
AACAATAAAATTTTTTTTCATGTTTTAACAAAAACCAATCAGGA

hide sequence

RefSeq Acc Id:

XM_008007311 ⟹ XP_008005502

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
mChlSab1.0.hap1	13	35,844,515 - 36,025,056 (-)	NCBI
Vero_WHO_p1.0	NW_023666040	34,319,593 - 34,527,658 (+)	NCBI
ChlSab1.1	13	61,988,287 - 62,218,753 (+)	NCBI

Sequence:

show sequence

GCCGCGGTGGTGGCGGCGGCGCGTCGTTGCAGTTGCGCCATCTGTCAGGAGCGGAGCCGGCGAG
GAGGGGGCTGCCGCGGGCGAGGAGGAGGGGTCGCCGCGAGCCGAAGGCCTTCGAGACCCGCCCG
CCGGCCGGCGGCGAGAGTAGAGGCGAGGTTGCCCTGCGAGCGGCGCGTCCTCTCCCACCCGGGC
GCGCCGCGCTTCTCCCGGCGCACCGAGGACCGCCCGGGCGCACACAAAGCCGCCGCCCGCGTCG
CACCGCCCGGCGGCCGCCGCCCGCGCCAGGGAGGGATCCGGCCGCCGGGCCGGGGACACCCCGG
CGCCGCCCCCTCCGTGCTCTCGGAAGGCCCACCGGCTCCTGGGCCCGCCGGGGAGCTCCCGGAG
CCGCCTCGGCCGCGCCGGAGGAGGGCGGGGAGAGGACCATGTGAATGGGCTCCGGAGCCTGAGC
GCCGCGCAGTTTTTTTGAAGAAGCAGAATGCTGATCTAGACGTGGAAAAAGACCAGTCCTGCCG
CTGTTGTAGAAGACATGTGGTGTATATAAAGTTTGTGATCGTTGGCGGAAATTCTGGAATTTAG
ATAATGGGCTGTGTGCAATGTAAGGATAAAGAAGCAACAAAACTGACGGAGGAGAGGGACGGCA
GCCTGAACCAGAGCTCCGGGTACCGCTATGGCACAGACCCCACCCCTCAGCACTACCCCAGCTT
CGGTGTGACCTCCATCCCCAACTACAACAACTTCCACGCAGCCGGGGGCCAAGGACTCACTGTC
TTTGGAGGTGTGAACTCTTCGTCTCATACGGGGACCTTGCGTACGAGAGGAGGAACAGGAGTGA
CACTGTTTGTGGCCCTTTATGACTATGAAGCACGGACGGAAGATGACCTGAGTTTTCACAAAGG
AGAAAAATTTCAAATATTGAACAGCTCGGAAGGAGATTGGTGGGAAGCCCGCTCCTTGACAACT
GGAGAGACAGGTTACATTCCCAGCAATTATGTGGCTCCAGTGGACTCTATCCAGGCAGAAGAGT
GGTACTTTGGAAAACTTGGCCGAAAAGATGCTGAGCGACAGCTATTGTCCTTTGGAAACCCAAG
AGGTACCTTTCTTATCCGCGAGAGTGAAACCACCAAAGGTGCCTATTCACTTTCCATCCGCGAT
TGGGATGATATGAAAGGAGACCACGTCAAACATTATAAAATTCGCAAACTTGACAACGGTGGAT
ACTACATTACCACCCGGGCCCAGTTTGAAACCCTTCAGCAGCTTGTACAACATTACTCAGAGAA
AGCTGATGGTTTGTGTTTTAACTTAACTGTGATTGCATCAAGTTGTACCCCACAAACTTCTGGA
TTGGCTAAAGATGCTTGGGAAGTTGCACGTCGTTCGTTGTGTCTGGAGAAGAAGCTGGGTCAGG
GGTGTTTCGCTGAAGTGTGGCTTGGTACCTGGAATGGAAACACAAAAGTAGCCATAAAGACTCT
TAAACCAGGCACAATGTCCCCCGAATCATTCCTTGAGGAAGCGCAGATCATGAAGAAGCTGAAG
CACGACAAGCTGGTCCAGCTCTACGCAGTGGTGTCTGAGGAGCCCATCTACATCGTCACCGAGT
ATATGAATAAAGGAAGTTTACTGGATTTCTTAAAAGATGGAGAAGGAAGAGCTCTGAAATTACC
AAATCTTGTGGACATGGCAGCACAGGTGGCTGCAGGAATGGCTTACATCGAGCGCATGAATTAT
ATCCATAGAGATCTGCGATCAGCAAACATTCTAGTGGGGAATGGACTCATATGCAAGATTGCTG
ATTTCGGATTGGCCCGATTGATCGAAGACAATGAGTACACAGCAAGACAAGGTGCAAAATTCCC
CATCAAGTGGACGGCCCCCGAGGCAGCCCTGTACGGGAGGTTCACAATCAAGTCTGACGTGTGG
TCTTTTGGAATCTTACTCACAGAGCTGGTCACCAAAGGAAGAGTGCCATACCCAGGCATGAACA
ACCGGGAGGTGCTGGAGCAGGTGGAGCGAGGCTACAGGATGCCGTGCCCGCAGGACTGCCCCAT
CTCTCTGCATGAGCTCATGATCCACTGCTGGAAAAAGGACCCTGAAGAACGCCCCACTTTTGAG
TACTTGCAGAGCTTCCTGGAAGACTACTTTACCGCCACAGAGCCCCAGTACCAACCTGGTGAAA
ACCTGTAAGGCCCGGGTCTGCCTGCGGAGAGAGGCCTTGTCCCAGAGGCTGCCCCACCCCTCCC
CATTAGCTTTCAATTCCGTAGCCGGCTGCTCCCCAGCAGCAGAACCGCCCAGGATCAGATTGCA
TGTGACTCTGAAGCTGACGAACTTCCATGGCCCTCATTAATGACACTTGTCCCCAAATCCGAAC
CTCCTCTGTGAAGCATTCGAGACAGAACCTTGTTATTTCTCAGACTTTGGAAAATGCATTGTAT
CGATGTTATGTAAAAGGCCAAACCTCTGTTCAGTGTAAATAGTTACTCCAGTGCCAACAATCCT
AGTGCTTTCCTTTTTTAAAAATGCAAATCCTATGTGATTTTAACTCTGTCTTCACCTGATTCAA
CTAAAAAAAAAAAGTATTATTTTCCAAAAGTGGCCTCTTTGTCTAAAACAATAAAATTTTTTTT
CATGTTTTAACAAAAACCAATCA

hide sequence

RefSeq Acc Id:

XM_038001005 ⟹ XP_037856933

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
mChlSab1.0.hap1	13	35,844,515 - 36,051,962 (-)	NCBI
Vero_WHO_p1.0	NW_023666040	34,319,593 - 34,527,658 (+)	NCBI

RefSeq Acc Id:

XM_038001006 ⟹ XP_037856934

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
mChlSab1.0.hap1	13	35,844,515 - 35,995,799 (-)	NCBI
Vero_WHO_p1.0	NW_023666040	34,376,143 - 34,528,593 (+)	NCBI

RefSeq Acc Id:

XM_073022418 ⟹ XP_072878519

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
mChlSab1.0.hap1	13	35,844,515 - 36,025,056 (-)	NCBI

RefSeq Acc Id:

XM_073022419 ⟹ XP_072878520

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
mChlSab1.0.hap1	13	35,844,515 - 35,937,068 (-)	NCBI

RefSeq Acc Id:

XM_073022420 ⟹ XP_072878521

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
mChlSab1.0.hap1	13	35,844,515 - 36,025,056 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_008005498	(Get FASTA)	NCBI Sequence Viewer
	XP_008005500	(Get FASTA)	NCBI Sequence Viewer
	XP_008005502	(Get FASTA)	NCBI Sequence Viewer
	XP_037856933	(Get FASTA)	NCBI Sequence Viewer
	XP_037856934	(Get FASTA)	NCBI Sequence Viewer
	XP_072878519	(Get FASTA)	NCBI Sequence Viewer
	XP_072878520	(Get FASTA)	NCBI Sequence Viewer
	XP_072878521	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000011676
	ENSCSAP00000011676.1

RefSeq Acc Id:	XP_008005502 ⟸ XM_008007311
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_008005498 ⟸ XM_008007307
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9RST7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_008005500 ⟸ XM_008007309
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9RST7 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000011676 ⟸ ENSCSAT00000013686

RefSeq Acc Id:	XP_037856933 ⟸ XM_038001005
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9RST7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_037856934 ⟸ XM_038001006
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9RST7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_072878521 ⟸ XM_073022420
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_072878519 ⟸ XM_073022418
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9RST7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_072878520 ⟸ XM_073022419
- Peptide Label:	isoform X1
- UniProtKB:	A0A0D9RST7 (UniProtKB/TrEMBL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000015591	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000013686.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.505.10	UniProtKB/TrEMBL
	Phosphorylase Kinase, domain 1	UniProtKB/TrEMBL
	SH3 Domains	UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	Fyn/Yrk_SH2	UniProtKB/TrEMBL
	Fyn/Yrk_SH3	UniProtKB/TrEMBL
	Kinase-like_dom_sf	UniProtKB/TrEMBL
	Non-receptor_tyrosine_kinases	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser-Thr/Tyr_kinase_cat_dom	UniProtKB/TrEMBL
	SH2	UniProtKB/TrEMBL
	SH2_dom_sf	UniProtKB/TrEMBL
	SH3-like_dom_sf	UniProtKB/TrEMBL
	SH3_domain	UniProtKB/TrEMBL
	Tyr_kinase_AS	UniProtKB/TrEMBL
	Tyr_kinase_cat_dom	UniProtKB/TrEMBL
KEGG Report	csab:103240563	UniProtKB/TrEMBL
NCBI Gene	FYN	ENTREZGENE
PANTHER	TYROSINE-PROTEIN KINASE	UniProtKB/TrEMBL
Pfam	Pkinase_Tyr	UniProtKB/TrEMBL
	SH2	UniProtKB/TrEMBL
	SH3_1	UniProtKB/TrEMBL
PRINTS	SH2DOMAIN	UniProtKB/TrEMBL
	SH3DOMAIN	UniProtKB/TrEMBL
	TYRKINASE	UniProtKB/TrEMBL
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_TYR	UniProtKB/TrEMBL
	SH2	UniProtKB/TrEMBL
	SH3	UniProtKB/TrEMBL
SMART	SH2	UniProtKB/TrEMBL
	SH3	UniProtKB/TrEMBL
	TyrKc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50044	UniProtKB/TrEMBL
	SSF55550	UniProtKB/TrEMBL
	SSF56112	UniProtKB/TrEMBL
UniProt	A0A0D9RST7	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - PID (archival)