Mag (myelin-associated glycoprotein) - Rat Genome Database
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Gene: Mag (myelin-associated glycoprotein) Rattus norvegicus
Analyze
Symbol: Mag
Name: myelin-associated glycoprotein
RGD ID: 3035
Description: Exhibits carboxylic acid binding activity; protein kinase binding activity; and signaling receptor binding activity. Involved in cell-cell adhesion via plasma-membrane adhesion molecules; cellular response to mechanical stimulus; and regulation of neurogenesis. Localizes to several cellular components, including Schmidt-Lanterman incisure; mesaxon; and myelin sheath adaxonal region. Used to study middle cerebral artery infarction and sciatic neuropathy. Biomarker of nerve compression syndrome. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 75. Orthologous to human MAG (myelin associated glycoprotein); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 3alpha-hydroxy-5beta-pregnan-20-one; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 1B236; brain neuron cytoplasmic protein 3; S-MAG (C-term.); sialic acid-binding Ig-like lectin 4a; siglec-4a
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2186,148,227 - 86,163,726 (-)NCBI
Rnor_6.0 Ensembl189,345,429 - 89,360,733 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0189,345,325 - 89,360,905 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0190,500,932 - 90,516,312 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4185,954,511 - 85,970,832 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1186,032,629 - 86,048,943 (-)NCBI
Celera180,517,171 - 80,532,485 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
1. Arquint M, etal., Proc Natl Acad Sci U S A 1987 Jan;84(2):600-4.
2. Buss A and Schwab ME, Glia. 2003 Jun;42(4):424-32.
3. Collins BE, etal., J Biol Chem. 1997 Jan 10;272(2):1248-55.
4. Domeniconi M, etal., Neuron 2002 Jul 18;35(2):283-90.
5. Franzen R, etal., J Cell Biol. 2001 Dec 10;155(6):893-8. Epub 2001 Dec 3.
6. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. Gupta R, etal., Exp Neurol. 2006 Aug;200(2):418-29. Epub 2006 Jun 9.
8. Gupta R, etal., J Orthop Res. 2005 Sep;23(5):1232-9. Epub 2005 Apr 25.
9. Hasegawa Y, etal., J Neurosci. 2004 Jul 28;24(30):6826-32.
10. Irving EA, etal., J Cereb Blood Flow Metab. 2005 Jan;25(1):98-107.
11. Johnson D, etal., J Neurochem. 1986 Apr;46(4):1086-93.
12. Lai C, etal., Proc Natl Acad Sci U S A 1987 Jun;84(12):4337-41.
13. Li X, etal., Neuroreport. 2009 May 6;20(7):708-12. doi: 10.1097/WNR.0b013e32832aa942.
14. Lin KY, etal., Vet Parasitol. 2010 Jul 15;171(1-2):74-80. doi: 10.1016/j.vetpar.2010.03.019. Epub 2010 Mar 30.
15. Mehta NR, etal., J Biol Chem. 2007 Sep 21;282(38):27875-86. Epub 2007 Jul 19.
16. MGD data from the GO Consortium
17. NCBI rat LocusLink and RefSeq merged data July 26, 2002
18. Ohlmann A, etal., Glia. 2003 Aug;43(2):128-40.
19. OMIM Disease Annotation Pipeline
20. Owens GC, etal., J Cell Biol. 1990 Sep;111(3):1171-82.
21. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
22. RGD automated import pipeline for gene-chemical interactions
23. Robak LA, etal., J Neurosci. 2009 May 6;29(18):5768-83. doi: 10.1523/JNEUROSCI.4935-08.2009.
24. Salzer JL, etal., J Cell Biol 1987 Apr;104(4):957-65.
25. Sanchez ES, etal., Glia. 2008 Jul;56(9):1017-27. doi: 10.1002/glia.20675.
26. Shields DC and Banik NL, Exp Eye Res. 1998 Oct;67(4):403-10.
27. Sternberger NH, etal., Proc Natl Acad Sci U S A. 1979 Mar;76(3):1510-4.
28. Stiles TL, etal., J Cell Sci. 2013 Jan 1;126(Pt 1):209-20. doi: 10.1242/jcs.113191. Epub 2012 Nov 6.
29. Sutcliffe JG, etal., Cell 1983 Jul;33(3):671-82.
30. Sutcliffe JG, etal., Cold Spring Harb Symp Quant Biol 1983;48 Pt 2:477-84.
31. Tang S, etal., J Cell Biol. 1997 Sep 22;138(6):1355-66.
32. Thompson HJ, etal., Eur J Neurosci. 2006 Dec;24(11):3063-72.
33. Tomita K, etal., Glia. 2007 Nov 1;55(14):1498-507.
34. Tropak MB, etal., Brain Res. 1988 Sep;464(2):143-55.
35. Venkatesh K, etal., J Neurosci. 2005 Jan 26;25(4):808-22.
Additional References at PubMed
PMID:1703542   PMID:2457152   PMID:4020419   PMID:6200494   PMID:9482783   PMID:10625334   PMID:11283023   PMID:12691736   PMID:12718855   PMID:12975355   PMID:16595691   PMID:17497667  
PMID:17634366   PMID:18922173   PMID:20071523   PMID:20308067   PMID:20731761   PMID:22871113   PMID:22926577   PMID:24101522   PMID:24129569   PMID:26179919   PMID:26335717   PMID:27583434  
PMID:27922006   PMID:29476059  


Genomics

Comparative Map Data
Mag
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2186,148,227 - 86,163,726 (-)NCBI
Rnor_6.0 Ensembl189,345,429 - 89,360,733 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0189,345,325 - 89,360,905 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0190,500,932 - 90,516,312 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4185,954,511 - 85,970,832 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1186,032,629 - 86,048,943 (-)NCBI
Celera180,517,171 - 80,532,485 (-)NCBICelera
Cytogenetic Map1q21NCBI
MAG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1935,292,125 - 35,313,807 (+)EnsemblGRCh38hg38GRCh38
GRCh381935,292,161 - 35,313,807 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371935,783,064 - 35,804,710 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh371935,782,989 - 35,804,710 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361940,474,878 - 40,496,547 (+)NCBINCBI36hg18NCBI36
Build 341940,474,877 - 40,496,547NCBI
Celera1932,496,476 - 32,518,142 (+)NCBI
Cytogenetic Map19q13.12NCBI
HuRef1932,291,486 - 32,313,186 (+)NCBIHuRef
CHM1_11935,784,610 - 35,806,322 (+)NCBICHM1_1
Mag
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39730,598,600 - 30,614,347 (-)NCBIGRCm39mm39
GRCm38730,899,175 - 30,914,922 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl730,899,176 - 30,914,873 (-)EnsemblGRCm38mm10GRCm38
MGSCv37731,684,202 - 31,699,851 (-)NCBIGRCm37mm9NCBIm37
MGSCv36730,607,943 - 30,623,592 (-)NCBImm8
Celera725,483,485 - 25,499,089 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map719.26NCBI
Mag
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554684,584,162 - 4,598,914 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554684,584,068 - 4,598,772 (+)NCBIChiLan1.0ChiLan1.0
MAG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11940,975,763 - 40,997,401 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1940,975,763 - 40,997,401 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01932,238,457 - 32,260,497 (+)NCBIMhudiblu_PPA_v0panPan3
MAG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1117,288,343 - 117,302,386 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11117,288,306 - 117,301,975 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Mag
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936570989,743 - 1,004,820 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl644,794,204 - 44,809,929 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1644,794,197 - 44,809,933 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2640,214,125 - 40,221,021 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAG
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1630,224,873 - 30,246,277 (+)NCBI
ChlSab1.1 Ensembl630,227,442 - 30,246,481 (+)Ensembl
Mag
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247948,237,005 - 8,251,933 (-)NCBI

Position Markers
UniSTS:143817  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0189,345,600 - 89,345,728NCBIRnor6.0
Rnor_5.0190,501,113 - 90,501,241UniSTSRnor5.0
RGSC_v3.4185,954,692 - 85,954,820UniSTSRGSC3.4
Celera180,517,352 - 80,517,480UniSTS
Cytogenetic Map1q21UniSTS
RH134668  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0189,345,655 - 89,345,866NCBIRnor6.0
Rnor_5.0190,501,168 - 90,501,379UniSTSRnor5.0
RGSC_v3.4185,954,747 - 85,954,958UniSTSRGSC3.4
Celera180,517,407 - 80,517,618UniSTS
RH 3.4 Map1843.3UniSTS
Cytogenetic Map1q21UniSTS
Mag  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0189,345,526 - 89,345,769NCBIRnor6.0
Rnor_5.0190,501,039 - 90,501,282UniSTSRnor5.0
RGSC_v3.4185,954,618 - 85,954,861UniSTSRGSC3.4
Celera180,517,278 - 80,517,521UniSTS
Cytogenetic Map1q21UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15655769122614963Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123406428108057505Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)125951907130917265Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134993530173445086Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13537750894364229Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)135377692217372257Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143579208126240667Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143579208126240667Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143579208126240667Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143579208126240667Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143579208126240667Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)143579208126240667Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143579208126240667Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)149147799156446783Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14957857794578577Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149578577169852184Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149578693217054291Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15052271494225616Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)157761301104391981Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)158209327103209327Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)158354072161711996Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)164588516125875986Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)166113339122614963Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)16722768394201552Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)179134941113593716Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)179689548124689548Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)17968976594909507Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)182788437239853971Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)183502376128502376Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)183656882126240667Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)185779320130779320Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)185917265130917265Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)186776571131776571Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)188634585106002500Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:702
Count of miRNA genes:242
Interacting mature miRNAs:290
Transcripts:ENSRNOT00000028544, ENSRNOT00000044532
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 29
Low 6 3 2 2 6 6 23 20 3 6
Below cutoff 2 18 37 22 13 22 2 4 10 22 19 7 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_017190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006228824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006228827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008759138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017589054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC111870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M11721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M14871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M16800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M22357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M36702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  V01544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X05301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X06554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X63419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000028544   ⟹   ENSRNOP00000028544
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl189,345,429 - 89,360,733 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000044532   ⟹   ENSRNOP00000041373
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl189,345,748 - 89,358,166 (-)Ensembl
RefSeq Acc Id: NM_017190   ⟹   NP_058886
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2186,148,321 - 86,163,640 (-)NCBI
Rnor_6.0189,345,419 - 89,360,733 (-)NCBI
Rnor_5.0190,500,932 - 90,516,312 (-)NCBI
RGSC_v3.4185,954,511 - 85,970,832 (-)RGD
Celera180,517,171 - 80,532,485 (-)RGD
Sequence:
RefSeq Acc Id: XM_006228824   ⟹   XP_006228886
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2186,148,227 - 86,163,718 (-)NCBI
Rnor_6.0189,345,325 - 89,360,904 (-)NCBI
Rnor_5.0190,500,932 - 90,516,312 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006228827   ⟹   XP_006228889
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2186,148,227 - 86,163,654 (-)NCBI
Rnor_6.0189,345,325 - 89,360,905 (-)NCBI
Rnor_5.0190,500,932 - 90,516,312 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008759138   ⟹   XP_008757360
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2186,148,227 - 86,163,726 (-)NCBI
Rnor_6.0189,345,325 - 89,360,904 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017589051   ⟹   XP_017444540
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2186,148,227 - 86,163,666 (-)NCBI
Rnor_6.0189,345,325 - 89,360,905 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017589052   ⟹   XP_017444541
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0189,345,325 - 89,360,129 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017589053   ⟹   XP_017444542
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0189,345,325 - 89,360,129 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017589054   ⟹   XP_017444543
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2186,148,258 - 86,163,718 (-)NCBI
Rnor_6.0189,345,500 - 89,360,902 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_058886   ⟸   NM_017190
- Peptide Label: precursor
- UniProtKB: P07722 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006228886   ⟸   XM_006228824
- Peptide Label: isoform X1
- UniProtKB: P07722 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006228889   ⟸   XM_006228827
- Peptide Label: isoform X2
- UniProtKB: G3V9B3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008757360   ⟸   XM_008759138
- Peptide Label: isoform X1
- UniProtKB: P07722 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017444540   ⟸   XM_017589051
- Peptide Label: isoform X1
- UniProtKB: P07722 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017444542   ⟸   XM_017589053
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017444541   ⟸   XM_017589052
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017444543   ⟸   XM_017589054
- Peptide Label: isoform X2
- UniProtKB: G3V9B3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000028544   ⟸   ENSRNOT00000028544
RefSeq Acc Id: ENSRNOP00000041373   ⟸   ENSRNOT00000044532
Protein Domains
Ig-like   Ig-like C2-type   Ig-like V-type

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689935
Promoter ID:EPDNEW_R459
Type:initiation region
Name:Mag_1
Description:myelin-associated glycoprotein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0189,360,759 - 89,360,819EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3035 AgrOrtholog
Ensembl Genes ENSRNOG00000021023 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000028544 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000041373 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000028544 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000044532 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CD80_C2-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29409 UniProtKB/Swiss-Prot
NCBI Gene 29409 ENTREZGENE
Pfam C2-set_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mag PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt G3V9B3 ENTREZGENE, UniProtKB/TrEMBL
  MAG_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P02685 UniProtKB/Swiss-Prot
  P07723 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Mag  Myelin-associated glycoprotein      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_transcript has two alternative splice products 728945