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Gene: Mag (myelin-associated glycoprotein) Rattus norvegicus
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Symbol: Mag
Name: myelin-associated glycoprotein
Description: Exhibits carboxylic acid binding activity; protein kinase binding activity; and signaling receptor binding activity. Involved in cell-cell adhesion via plasma-membrane adhesion molecules; cellular response to mechanical stimulus; and regulation of neurogenesis. Localizes to several cellular components, including the Schmidt-Lanterman incisure; mesaxon; and myelin sheath adaxonal region. Used to study middle cerebral artery infarction and sciatic neuropathy. Biomarker of nerve compression syndrome. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 75. Orthologous to human MAG (myelin associated glycoprotein); INTERACTS WITH 3alpha-hydroxy-5beta-pregnan-20-one; 3H-1,2-dithiole-3-thione; 4-aminopyridine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 1B236; brain neuron cytoplasmic protein 3; S-MAG (C-term.); sialic acid-binding Ig-like lectin 4a; siglec-4a
Orthologs:
Homo sapiens (human) : MAG (myelin associated glycoprotein)  HGNC  Alliance
Mus musculus (house mouse) : Mag (myelin-associated glycoprotein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mag (myelin associated glycoprotein)
Pan paniscus (bonobo/pygmy chimpanzee) : MAG (myelin associated glycoprotein)
Canis lupus familiaris (dog) : MAG (myelin associated glycoprotein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mag (myelin associated glycoprotein)
Sus scrofa (pig) : MAG (myelin associated glycoprotein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0189,345,325 - 89,360,905 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0190,500,932 - 90,516,312 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4185,954,511 - 85,970,832 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1186,032,629 - 86,048,943 (-)NCBI
Celera180,517,171 - 80,532,485 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mag
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3035
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.