Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

VASCULAR ENDOTHELIAL GROWTH FACTOR SIGNALING PATHWAY (PW:0000243)

View Ontology Report

Description
Vascular endothelial growth factor signaling pathway (VEGF) regulates vasculogenesis, angiogenesis, lymphanogiogenesis and vascular permeability as well as the migration of monocytes and macrophages and the recruitment of haematopoietic cells. Several VEGFs (five in mammals) bind to one or more of the three VEGF receptor tyrosine kinases (RTK) to accomplish these important vascular functions. By far, the best characterized receptor and the focus of this synopsis and diagram is Kdr also known as

Pathway Diagram:

Ariadne Genomics Inc. Flt4 --+> vasculogenesis/lymphangiogensis Prkcb --+> the extracellular signal-regulated Raf/Mek/Erk signaling pathway Prkca --+> the extracellular signal-regulated Raf/Mek/Erk signaling pathway Prkcz --+> the extracellular signal-regulated Raf/Mek/Erk signaling pathway DAG --+> Prkca DAG --+> Prkcb DAG --+> Prkcz the extracellular signal-regulated Raf/Mek/Erk signaling pathway --+> cell proliferation phosphatidylinositol 3-kinase-Akt signaling pathway --+> cell survival Plcg1 --+> PIP3 SHB --+> phosphatidylinositol 3-kinase-Akt signaling pathway Kdr --+> vasculogenesis/angiogensis Kdr p38 MAPK signaling pathway --+> actin remodeling Nck1 --+> p38 MAPK signaling pathway Flt1 --+> vascular permeability/monocyte migration/haematopoiesis Nrp2 Nrp1 vascular permeability/monocyte migration/haematopoiesis Ptk2 Plcg1 Fyn Nck1 Sh2d2a Prkca Prkcb Prkcz SHB Flt4 Figf Vegfc Flt1 Vegfa Pgf DAG Fyn ---- Nck1 Kdr ---- Sh2d2a Kdr --+> Plcg1 Flt1 ---- Vegfb Flt1 ---- Pgf Flt1 ---- Vegfa Flt4 ---- Vegfc Figf ---- Flt4 Kdr ---- Nck1 Kdr ---- SHB Kdr ---- Vegfa IP3 Nrp1 ---- Vegfa Nrp2 ---- Vegfa Ptk2 ---- SHB p38 MAPK signaling pathway phosphatidylinositol 3-kinase-Akt signaling pathway cell survival Vegfb cell proliferation PIP3 the extracellular signal-regulated Raf/Mek/Erk signaling pathway actin remodeling vasculogenesis/angiogensis vasculogenesis/lymphangiogensis
GO TO:

Genes in Pathway:
show annotations for term's descendants           Sort by:
vascular endothelial growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap1 A-kinase anchoring protein 1 ISO PID PID:200188 NCBI chr10:74,118,232...74,151,366
Ensembl chr10:74,119,124...74,138,190 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO
IEA 		PID
KEGG		 PID:200188 rno:04370 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 IEA KEGG rno:04370 NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:92,014,859...92,061,420 		JBrowse link
G Akt3 AKT serine/threonine kinase 3 IEA KEGG rno:04370 NCBI chr13:91,475,839...91,758,060
Ensembl chr13:91,475,839...91,748,020 		JBrowse link
G Arf1 ARF GTPase 1 ISO PID PID:200188 NCBI chr10:44,497,543...44,513,994 JBrowse link
G Bad BCL2-associated agonist of cell death IEA KEGG rno:04370 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase ISO PID PID:200188 NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:69,342,813...69,476,931 		JBrowse link
G Calm1 calmodulin 1 ISO PID PID:200188 NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:125,217,246...125,225,381 		JBrowse link
G Calm2 calmodulin 2 ISO PID PID:200188 NCBI chr 6:12,845,170...12,857,830
Ensembl chr15:64,519,554...64,520,657
Ensembl chr 6:64,519,554...64,520,657 		JBrowse link
G Calm3 calmodulin 3 ISO PID PID:200188 NCBI chr 1:86,718,761...86,725,869
Ensembl chr 1:86,717,321...86,725,960 		JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 ISO PID PID:200188 NCBI chr12:39,451,828...39,505,719
Ensembl chr12:39,451,834...39,514,964 		JBrowse link
G Casp9 caspase 9 IEA KEGG rno:04370 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cav1 caveolin 1 ISO PID PID:200188 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740 		JBrowse link
G Cbl Cbl proto-oncogene ISO PID PID:200188 NCBI chr 8:53,384,656...53,468,067
Ensembl chr 8:53,384,656...53,468,067 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IMP RGD PMID:14693680 RGD:1580560 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Cdc42 cell division cycle 42 ISO
IEA 		PID
KEGG		 PID:200188 rno:04370 NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:154,839,631...154,876,627 		JBrowse link
G Cdh5 cadherin 5 ISO PID PID:200188 NCBI chr19:821,875...860,931
Ensembl chr19:822,464...860,822 		JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 IEA KEGG rno:04370 NCBI chr 3:126,989,800...127,025,071
Ensembl chr 3:126,989,579...127,042,443 		JBrowse link
G Chp1l1 calcineurin-like EF-hand protein 1 like 1 IEA KEGG rno:04370 NCBI chr 5:73,364,780...73,367,229
Ensembl chr 5:73,363,560...73,367,249 		JBrowse link
G Chp2 calcineurin-like EF hand protein 2 IEA KEGG rno:04370 NCBI chr 1:186,189,090...186,203,663
Ensembl chr 1:186,185,151...186,203,667 		JBrowse link
G Ctnna1 catenin alpha 1 ISO PID PID:200188 NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,999,820...27,135,007 		JBrowse link
G Ctnnb1 catenin beta 1 ISO PID PID:200188 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Dnm2 dynamin 2 ISO PID PID:200188 NCBI chr 8:28,254,344...28,336,297
Ensembl chr 8:28,254,529...28,336,295 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 ISS RGD PMID:14597660 RGD:1334466 NCBI chr19:69,765,276...69,804,681 JBrowse link
G Egln2 egl-9 family hypoxia-inducible factor 2 TAS
ISS 		RGD PMID:12876291 PMID:14597660 RGD:727754, RGD:1334466 NCBI chr 1:91,579,205...91,586,985
Ensembl chr 1:91,579,206...91,587,385 		JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 ISS RGD PMID:14597660 RGD:1334466 NCBI chr 6:77,385,549...77,411,015
Ensembl chr 6:77,385,549...77,411,015 		JBrowse link
G Fbxw11 F-box and WD repeat domain containing 11 ISO PID PID:200188 NCBI chr10:17,737,181...17,834,834
Ensembl chr10:17,720,444...17,834,834 		JBrowse link
G Fes FES proto-oncogene, tyrosine kinase ISO PID PID:200188 NCBI chr 1:143,746,945...143,756,181
Ensembl chr 1:143,746,945...143,756,181 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 IMP
ISO 		PID
RGD		 PMID:15785231 PMID:16633338 PID:200109 PID:200188, RGD:1626621, RGD:2298727 NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750 		JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 IMP
ISO 		This is VGFR-3 PID
RGD		 PMID:11683876 PID:200109, RGD:727326 NCBI chr10:34,414,834...34,455,878
Ensembl chr10:34,414,733...34,456,645 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase ISO PID
RGD		 PMID:17658244 PID:200188, RGD:2298729 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:44,322,361...44,515,479 		JBrowse link
G Gab1 GRB2-associated binding protein 1 ISO PID PID:200188 NCBI chr19:44,035,693...44,143,617
Ensembl chr19:44,035,063...44,143,617 		JBrowse link
G Grb10 growth factor receptor bound protein 10 ISO PID PID:200188 NCBI chr14:90,708,653...90,816,399
Ensembl chr14:90,708,653...90,816,387 		JBrowse link
G Grb2 growth factor receptor bound protein 2 ISO PID PID:200188 NCBI chr10:101,380,354...101,448,138
Ensembl chr10:101,380,356...101,448,138 		JBrowse link
G Hgs hepatocyte growth factor-regulated tyrosine kinase substrate ISO PID PID:200188 NCBI chr10:106,237,988...106,256,174
Ensembl chr10:106,237,824...106,256,174 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IMP RGD PMID:18614764 RGD:2301848 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hras HRas proto-oncogene, GTPase IEA KEGG rno:04370 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 ISO PID PID:200188 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 ISO PID PID:200188 NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IEA KEGG rno:04370 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301 		JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 ISO PID PID:200188 NCBI chr 1:144,088,788...144,178,989
Ensembl chr 1:144,088,793...144,179,043 		JBrowse link
G Itgav integrin subunit alpha V ISO PID PID:200188 NCBI chr 3:89,245,382...89,333,512
Ensembl chr 3:89,245,095...89,333,511 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO PID PID:200188 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:90,009,900...90,067,800 		JBrowse link
G Kdr kinase insert domain receptor IMP
IEA
ISO 		VEGFR-2 KEGG
PID
RGD		 PMID:9442048 PMID:18614764 PMID:17658244 PMID:16633338 PMID:15785231 More... PID:200109 PID:200188 rno:04370, RGD:729081, RGD:2301848, RGD:2298729, RGD:2298727, RGD:1626621, RGD:2292019 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192 		JBrowse link
G Kras KRAS proto-oncogene, GTPase IEA KEGG rno:04370 NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ISO
IEA 		PID
KEGG		 PID:200188 rno:04370 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 ISO
IEA 		PID
KEGG		 PID:200188 rno:04370 NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940 		JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 ISO PID PID:200188 NCBI chr10:46,107,639...46,128,986
Ensembl chr10:46,106,548...46,129,004 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 ISO PID PID:200188 NCBI chr10:95,872,747...95,987,747
Ensembl chr10:95,872,546...95,987,721 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 ISO
IEA 		PID
KEGG		 PID:200188 rno:04370 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk11 mitogen-activated protein kinase 11 ISO
IEA 		PID
KEGG		 PID:200188 rno:04370 NCBI chr 7:122,098,120...122,105,023
Ensembl chr 7:122,098,121...122,105,038 		JBrowse link
G Mapk12 mitogen-activated protein kinase 12 IEA KEGG rno:04370 NCBI chr 7:122,085,647...122,096,307
Ensembl chr 7:122,085,913...122,096,307 		JBrowse link
G Mapk13 mitogen activated protein kinase 13 IEA KEGG rno:04370 NCBI chr20:6,836,979...6,847,197
Ensembl chr20:6,837,013...6,847,191 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 ISO
IEA 		PID
KEGG		 PID:200188 rno:04370 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 ISO
IEA 		PID
KEGG		 PID:200188 rno:04370 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 ISO
IEA 		PID
KEGG		 PID:200188 rno:04370 NCBI chr13:45,066,027...45,112,326
Ensembl chr13:45,066,031...45,112,326 		JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 IEA KEGG rno:04370 NCBI chr 8:116,808,429...116,842,228
Ensembl chr 8:116,808,429...116,842,228 		JBrowse link
G Myof myoferlin ISO PID PID:200188 NCBI chr 1:245,086,109...245,234,768
Ensembl chr 1:245,086,109...245,234,768 		JBrowse link
G Nck1 NCK adaptor protein 1 ISO PID
RGD		 PMID:17658244 PID:200188, RGD:2298729 NCBI chr 8:109,897,723...109,958,247
Ensembl chr 8:109,897,724...109,958,247 		JBrowse link
G Nck2 NCK adaptor protein 2 ISO PID PID:200188 NCBI chr 9:53,206,006...53,332,417
Ensembl chr 9:53,231,381...53,332,394 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase ISO PID PID:200188 NCBI chr 8:82,264,751...82,349,642
Ensembl chr 8:82,264,649...82,349,633 		JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 IEA KEGG rno:04370 NCBI chr19:52,108,982...52,196,418
Ensembl chr19:52,109,483...52,196,418 		JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 IEA KEGG rno:04370 NCBI chr 3:177,615,189...177,747,493
Ensembl chr 3:177,618,314...177,747,380 		JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 IEA KEGG rno:04370 NCBI chr19:50,870,464...50,944,992
Ensembl chr19:50,870,489...50,944,992 		JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 IEA KEGG rno:04370 NCBI chr15:33,256,912...33,284,522
Ensembl chr15:33,274,153...33,285,582 		JBrowse link
G Nos3 nitric oxide synthase 3 ISO
IEA 		PID
KEGG		 PID:200188 rno:04370 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664 		JBrowse link
G Nras NRAS proto-oncogene, GTPase IEA KEGG rno:04370 NCBI chr 2:193,271,399...193,282,023
Ensembl chr 2:193,271,430...193,278,543 		JBrowse link
G Nrp1 neuropilin 1 ISS
ISO 		PID
RGD		 PMID:15563310 PMID:16633338 PID:200109, RGD:1334463, RGD:2298727 NCBI chr19:73,256,557...73,411,705
Ensembl chr19:73,256,557...73,411,702 		JBrowse link
G Nrp2 neuropilin 2 ISO PID PID:200109 NCBI chr 9:71,616,602...71,731,869
Ensembl chr 9:71,616,657...71,731,871 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 ISO PID PID:200188 NCBI chr11:82,212,896...82,273,803
Ensembl chr11:82,212,951...82,273,803 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 ISO PID PID:200188 NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,610,063...13,679,181 		JBrowse link
G Pgf placental growth factor TAS
ISO 		RGD PMID:7706320 PMID:16633338 RGD:633657, RGD:2298727 NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:110,547,153...110,557,747 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO
IEA 		PID
KEGG		 PID:200188 rno:04370 NCBI chr 2:117,103,643...117,177,411
Ensembl chr 2:117,143,468...117,177,411 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta IEA KEGG rno:04370 NCBI chr 8:108,474,017...108,579,140
Ensembl chr 8:108,474,019...108,579,331 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta IEA KEGG rno:04370 NCBI chr 5:165,377,994...165,426,620
Ensembl chr 5:165,377,994...165,403,968 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO
IEA 		PID
KEGG		 PID:200188 rno:04370 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347 		JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 IEA KEGG rno:04370 NCBI chr16:18,699,389...18,708,045
Ensembl chr16:18,699,448...18,709,665 		JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 IEA KEGG rno:04370 NCBI chr 5:134,936,790...135,009,303
Ensembl chr 5:134,934,857...135,007,762 		JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 IEA KEGG rno:04370 NCBI chr10:53,631,469...53,699,550
Ensembl chr10:53,631,476...53,699,539 		JBrowse link
G Pla2g10 phospholipase A2, group X IEA KEGG rno:04370 NCBI chr10:2,104,927...2,117,998
Ensembl chr10:2,104,927...2,116,172 		JBrowse link
G Pla2g12a phospholipase A2, group XIIA IEA KEGG rno:04370 NCBI chr 2:221,110,722...221,126,966
Ensembl chr 2:221,110,685...221,126,964 		JBrowse link
G Pla2g12b phospholipase A2, group XIIB IEA KEGG rno:04370 NCBI chr20:27,910,620...27,931,734
Ensembl chr20:27,913,259...27,932,148 		JBrowse link
G Pla2g1b phospholipase A2 group IB IEA KEGG rno:04370 NCBI chr12:46,802,932...46,814,511
Ensembl chr12:46,802,939...46,813,693 		JBrowse link
G Pla2g2a phospholipase A2 group IIA IEA KEGG rno:04370 NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297 		JBrowse link
G Pla2g2c phospholipase A2, group IIC IEA KEGG rno:04370 NCBI chr 5:156,241,142...156,262,368
Ensembl chr 5:156,242,451...156,264,676 		JBrowse link
G Pla2g2d phospholipase A2, group IID IEA KEGG rno:04370 NCBI chr 5:156,299,374...156,305,816
Ensembl chr 5:156,297,777...156,305,812 		JBrowse link
G Pla2g2f phospholipase A2, group IIF IEA KEGG rno:04370 NCBI chr 5:156,270,077...156,276,464
Ensembl chr 5:156,270,077...156,295,516 		JBrowse link
G Pla2g3 phospholipase A2, group III IEA KEGG rno:04370 NCBI chr14:82,589,908...82,597,542
Ensembl chr14:82,591,862...82,597,542 		JBrowse link
G Pla2g4a phospholipase A2 group 4A IEA KEGG rno:04370 NCBI chr13:64,427,921...64,572,352
Ensembl chr13:64,427,916...64,589,641 		JBrowse link
G Pla2g4b phospholipase A2 group IVB IEA KEGG rno:04370 NCBI chr 3:127,458,022...127,467,637
Ensembl chr 3:127,459,273...127,467,637 		JBrowse link
G Pla2g4e phospholipase A2, group IVE IEA KEGG rno:04370 NCBI chr 3:127,586,318...127,652,369
Ensembl chr 3:127,587,027...127,651,868 		JBrowse link
G Pla2g4f phospholipase A2, group IVF IEA KEGG rno:04370 NCBI chr 3:127,702,603...127,720,429
Ensembl chr 3:127,703,841...127,718,348 		JBrowse link
G Pla2g5 phospholipase A2, group V IEA KEGG rno:04370 NCBI chr 5:156,324,628...156,393,065
Ensembl chr 5:156,324,629...156,381,926 		JBrowse link
G Pla2g6 phospholipase A2 group VI IEA KEGG rno:04370 NCBI chr 7:112,731,803...112,771,978
Ensembl chr 7:112,731,803...112,771,609 		JBrowse link
G Plcg1 phospholipase C, gamma 1 ISO
IEA 		KEGG
PID
RGD		 PMID:17658244 PID:200188 rno:04370, RGD:2298729 NCBI chr 3:169,805,299...169,836,040
Ensembl chr 3:169,804,846...169,836,050 		JBrowse link
G Plcg2 phospholipase C, gamma 2 IEA KEGG rno:04370 NCBI chr19:62,456,196...62,592,684
Ensembl chr19:62,453,259...62,592,684 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha IEA KEGG rno:04370 NCBI chr 2:227,839,058...228,113,560
Ensembl chr 2:227,839,062...228,113,554 		JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta IEA KEGG rno:04370 NCBI chr15:3,809,182...3,854,204
Ensembl chr15:3,809,262...3,854,203 		JBrowse link
G Ppp3cc protein phosphatase 3 catalytic subunit gamma IEA KEGG rno:04370 NCBI chr15:51,699,586...51,771,763
Ensembl chr15:51,700,255...51,771,538 		JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha IEA KEGG rno:04370 NCBI chr14:95,758,333...95,808,015 JBrowse link
G Ppp3r2 protein phosphatase 3, regulatory subunit B, beta IEA KEGG rno:04370 NCBI chr 5:68,822,387...68,823,382
Ensembl chr 5:68,822,387...68,823,818 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 ISO PID PID:200188 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 ISO PID PID:200188 NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324 		JBrowse link
G Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1 ISO PID PID:200188 NCBI chr12:46,248,971...46,259,487
Ensembl chr12:46,249,010...46,259,482 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha ISO PID PID:200188 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494 		JBrowse link
G Prkag1 protein kinase AMP-activated non-catalytic subunit gamma 1 ISO PID PID:200188 NCBI chr 7:131,842,058...131,859,484
Ensembl chr 7:131,842,060...131,859,503 		JBrowse link
G Prkca protein kinase C, alpha ISO
IEA 		KEGG
PID
RGD		 PMID:17658244 PID:200188 rno:04370, RGD:2298729 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572 		JBrowse link
G Prkcb protein kinase C, beta ISO
IEA 		KEGG
RGD		 PMID:17658244 rno:04370, RGD:2298729 NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:186,263,447...186,594,740 		JBrowse link
G Prkcd protein kinase C, delta IMP
ISO 		PID
RGD		 PMID:15541367 PID:200188, RGD:2298730 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839 		JBrowse link
G Prkcg protein kinase C, gamma IEA KEGG rno:04370 NCBI chr 1:74,748,272...74,777,611
Ensembl chr 1:74,748,272...74,774,814 		JBrowse link
G Prkcz protein kinase C, zeta ISO RGD PMID:17658244 RGD:2298729 NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:171,101,774...171,212,674 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IEA KEGG rno:04370 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Ptk2 protein tyrosine kinase 2 ISO
IEA 		KEGG
RGD		 PMID:17658244 rno:04370, RGD:2298729 NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta ISO PID PID:200188 NCBI chr15:44,536,275...44,656,754
Ensembl chr15:44,531,249...44,656,806 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 ISO PID PID:200188 NCBI chr12:41,026,079...41,085,577
Ensembl chr12:41,043,785...41,085,577 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 ISO PID PID:200188 NCBI chr 4:159,212,320...159,237,069
Ensembl chr 4:159,212,320...159,237,069 		JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J ISO PID PID:200188 NCBI chr 3:96,861,785...97,017,702
Ensembl chr 3:96,861,785...97,017,656 		JBrowse link
G Pxn paxillin ISO
IEA 		PID
KEGG		 PID:200188 rno:04370 NCBI chr12:46,721,546...46,768,706
Ensembl chr12:46,721,546...46,768,697 		JBrowse link
G Rac1 Rac family small GTPase 1 IEA KEGG rno:04370 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109 		JBrowse link
G Rac2 Rac family small GTPase 2 IEA KEGG rno:04370 NCBI chr 7:111,981,825...112,009,201
Ensembl chr 7:111,996,742...112,009,267 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase ISO
IEA 		PID
KEGG		 PID:200188 rno:04370 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813 		JBrowse link
G RGD1560225 similar to nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 IEA KEGG rno:04370
G RGD1565588 similar to calcium binding protein P22 IEA KEGG rno:04370
G Rhoa ras homolog family member A ISO PID PID:200188 NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 ISO PID PID:200188 NCBI chr18:1,387,360...1,509,218
Ensembl chr18:1,387,360...1,509,147 		JBrowse link
G Sh2d2a SH2 domain containing 2A ISO
IEA 		KEGG
PID
RGD		 PMID:17658244 PID:200188 rno:04370, RGD:2298729 NCBI chr 2:175,610,127...175,616,685
Ensembl chr 2:175,609,874...175,616,685 		JBrowse link
G Shb SH2 domain containing adaptor protein B ISO PID PID:200188 NCBI chr 5:64,473,694...64,581,072
Ensembl chr 5:64,473,694...64,581,072 		JBrowse link
G Shc2 SHC adaptor protein 2 IEA KEGG rno:04370 NCBI chr 7:10,717,320...10,739,539
Ensembl chr 7:10,717,320...10,739,539 		JBrowse link
G Sphk1 sphingosine kinase 1 IEA KEGG rno:04370 NCBI chr10:102,257,413...102,263,086
Ensembl chr10:102,258,975...102,263,082 		JBrowse link
G Sphk2 sphingosine kinase 2 IEA KEGG rno:04370 NCBI chr 1:105,317,332...105,324,985
Ensembl chr 1:105,317,333...105,321,637 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO
IEA 		PID
KEGG		 PID:200188 rno:04370 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462 		JBrowse link
G Vcl vinculin ISO PID PID:200188 NCBI chr15:3,315,069...3,404,891
Ensembl chr15:3,315,069...3,405,163 		JBrowse link
G Vegfa vascular endothelial growth factor A IDA
IEA
IMP
ISO 		KEGG
RGD		 PMID:12181492 PMID:16160062 PMID:18614764 PMID:16633338 PMID:18221855 More... rno:04370, RGD:625593, RGD:2301956, RGD:2301848, RGD:2298727, RGD:2292019, RGD:1626621 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vegfb vascular endothelial growth factor B ISS
ISO 		RGD PMID:15563310 PMID:16633338 RGD:1334463, RGD:2298727 NCBI chr 1:213,601,570...213,607,254
Ensembl chr 1:213,600,966...213,607,152 		JBrowse link
G Vegfc vascular endothelial growth factor C IMP
ISO 		PID
RGD		 PMID:11683876 PMID:16633338 PID:200109, RGD:727326, RGD:2298727 NCBI chr16:44,445,293...44,560,887
Ensembl chr16:44,445,293...44,560,887 		JBrowse link
G Vegfd vascular endothelial growth factor D IMP
ISO 		This is the VEGF-D PID
RGD		 PMID:11683876 PMID:16633338 PID:200109, RGD:727326, RGD:2298727 NCBI chr  X:33,704,582...33,740,305
Ensembl chr  X:33,706,055...33,740,167 		JBrowse link
G Vtn vitronectin ISO PID PID:200188 NCBI chr10:63,892,782...63,895,862
Ensembl chr10:63,892,766...63,895,860 		JBrowse link
altered vascular endothelial growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt4 Fms related receptor tyrosine kinase 4 ISS RGD PMID:15563310 RGD:1334463 NCBI chr10:34,414,834...34,455,878
Ensembl chr10:34,414,733...34,456,645 		JBrowse link
altered vascular endothelial growth factor signaling pathway involving proteins affecting its expression term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdr kinase insert domain receptor IMP RGD PMID:18221855 RGD:2292019 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO RGD PMID:18221855 RGD:2292019 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
altered vascular endothelial growth factor signaling pathway involving the main players term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt4 Fms related receptor tyrosine kinase 4 ISS RGD PMID:15563310 RGD:1334463 NCBI chr10:34,414,834...34,455,878
Ensembl chr10:34,414,733...34,456,645 		JBrowse link
G Kdr kinase insert domain receptor IMP RGD PMID:18221855 RGD:2292019 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO RGD PMID:18221855 RGD:2292019 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link

Pathway Gene Annotations

Disease Annotations Associated with Genes in the vascular endothelial growth factor signaling pathway
Disease TermsGene Symbols
3-hydroxy-3-methylglutaryl-CoA lyase deficiencyCdc42 , Pla2g2a , Pla2g2c , Pla2g2d , Pla2g2f , Pla2g5
abdominal aortic aneurysmCav1 , Ccl2 , Itgav , Ptgs2
Aberrant Crypt FociCtnnb1 , Mapk1 , Mapk3
Abnormalities, Drug-InducedRhoa
achondrogenesis type IACalm1
acoustic neuromaCav1 , Vegfa
ACTH-independent macronodular adrenal hyperplasia 1Prkaca
Actin-Accumulation MyopathyEgln1
Acute Anterior UveitisCcl2
acute chest syndromeNos3 , Vegfa
Acute Coronary SyndromeItgb3 , Vcl
Acute Experimental PancreatitisKras
acute kidney failureBad , Egln1 , Egln3 , Hif1a , Nos3 , Ptgs2 , Vegfa
Acute Liver FailureCasp9 , Ccl2 , Nos3 , Ptgs2
Acute Lung InjuryAkt1 , Cav1 , Ccl2 , Flt1 , Kdr , Pgf , Pla2g2a , Prkaa1 , Ptgs2 , Vegfa
acute lymphoblastic leukemiaKras , Nos3 , Nras
acute myeloid leukemiaCbl , Ccl2 , Ctnna1 , Hras , Hspb1 , Itgav , Itgb3 , Kras , Nos3 , Nras , Ptpn11 , Rac2 , Vegfa
acute myocardial infarctionPlcg1 , Rhoa
acute necrotizing pancreatitisCcl2
acute pancreatitisArf1
acute promyelocytic leukemiaAkt1 , Nras , Ptpn11 , Rock1
Acute-On-Chronic Liver FailureCcl2
Acute-Phase ReactionHif1a
adenocarcinomaAkt1 , Akt2 , Ctnnb1 , Kdr , Kras , Nos3 , Pik3ca , Ptgs2 , Ptpn11 , Sphk1 , Vegfa
adenoid cystic carcinomaHras , Map2k2 , Pik3ca
adenomaCtnnb1 , Kras
adenylosuccinase lyase deficiencyPla2g6 , Rac2
adhesions of uterusKdr , Vegfa
Adrenal Cortex NeoplasmsCtnnb1
adrenal cortical adenomaPrkaca
Adrenal Gland NeoplasmsCdc42 , Ctnnb1 , Prkaca , Ptgs2
Adrenal InsufficiencyPla2g2a
adrenocortical carcinomaBraf , Ctnnb1
adult respiratory distress syndromeCcl2 , Pla2g2a , Pla2g4a
adult T-cell leukemia/lymphomaFyn , Nras , Plcg1 , Prkcb
adult-onset Still's diseaseVegfa
agammaglobulinemia 7Pik3r1
age related macular degenerationCcl2
Agenesis of Corpus CallosumPik3ca
aggressive periodontitisCcl2
Aicardi-Goutieres Syndrome 1Rhoa
Aicardi-Goutieres Syndrome 5Src
Alazami SyndromeCtnnb1
AlbuminuriaNck1 , Nck2 , Ptgs2
alcohol dependenceAkt1 , Calm1 , Calm2 , Calm3 , Fyn , Mapk1 , Mapk3
alcohol use disorderCasp9 , Mapk1 , Mapk14 , Mapk3
Alcohol Withdrawal DeliriumPtgs2
alcohol withdrawal syndromeCalm1 , Calm2 , Calm3
alcoholic hepatitisAkt1 , Ccl2
Alcoholic Liver DiseasesAkt1 , Cav1 , Hif1a , Vegfa
allergic conjunctivitisCcl2 , Pla2g2a
allergic contact dermatitisFlt1 , Kdr , Vegfa
allergic diseaseCcl2 , Map2k6
allergic rhinitisPtgs2
alopeciaRhoa
alpha-mannosidosisDnm2
Alveolar Bone LossItgav , Vtn
Alzheimer's diseaseAkt1 , Bad , Calm1 , Casp9 , Cav1 , Cdc42 , Ctnnb1 , Fyn , Hif1a , Hras , Hsp90aa1 , Hspb1 , Mapk1 , Mapk14 , Mapk3 , Nck2 , Nos3 , Nrp1 , Pik3r1 , Plcg1 , Plcg2 , Ppp3r1 , Prkcb , Ptgs2 , Ptk2b , Vegfa
Alzheimer's disease 1Nos3
ameloblastomaBraf
amenorrheaMap2k2 , Prkaa1
amphetamine abuseAkt1 , Prkaca
amyotrophic lateral sclerosisAkt1 , Bad , Casp9 , Cav1 , Kdr , Mapk14 , Pgf , Pla2g4a , Ptgs2 , Vegfa
amyotrophic lateral sclerosis type 1Vegfa
AnaphylaxisPtgs2
AnaplasiaHif1a
anaplastic astrocytomaKras
anaplastic large cell lymphomaHsp90aa1
anemiaCcl2 , Kras , Nras
AngiofibromaCtnnb1
angiosarcomaCtnnb1 , Flt1 , Hras , Kdr , Kras , Plcg1 , Vegfa , Vegfc
angle-closure glaucomaNos3
Animal Disease ModelsAkt1 , Ctnnb1 , Kras , Mapk1 , Mapk3 , Prkcg , Rhoa
Animal HepatitisCcl2
Animal Mammary NeoplasmsCdc42 , Hras , Kdr , Map2k6 , Pik3r1
ankylosing spondylitisPgf
anogenital venereal wartPtpn11 , Ptpn6
AnorexiaPtgs2
anterior ischemic optic neuropathyNos3
anterior uveitisCcl2
anti-basement membrane glomerulonephritisCcl2 , Mapk14 , Ptk2b
anuriaPrkab1
Aortic Aneurysm, Giant CongenitalBraf
aortic valve diseaseNos3
aortic valve stenosisPpp3cb , Ptpn11
arrhythmogenic right ventricular cardiomyopathyPtpn11
Arterial Occlusive DiseasesItgb3
Arterial ThrombosisHif1a
arteriosclerosisCcl2 , Itgb3 , Kdr , Nos3 , Ptgs2
Arteriovenous FistulaNos3 , Vegfa
arteriovenous malformationHras , Map2k1 , Pik3ca
arteriovenous malformations of the brainBraf , Flt1 , Kdr , Kras , Vegfa
Arthrogryposis, Cleft Palate, Craniosynostosis, and Impaired Intellectual DevelopmentPpp3ca
AsphyxiaHif1a
asphyxia neonatorumPtgs2
aspirin-induced respiratory diseasePtgs2
asthmaCcl2 , Hif1a , Itgb3 , Kdr , Nos3 , Pgf , Pla2g4a , Ptgs2 , Rhoa , Vegfa
astroblastomaPik3r1
ataxia telangiectasiaBraf
ataxia with oculomotor apraxia type 3Pik3r5
ataxia-telangiectasia-like disorder-1Ctnnb1
atherosclerosisAkt1 , Cav1 , Ccl2 , Ctnnb1 , Egln1 , Kdr , Nos3 , Pgf , Pla2g2a , Ptgs2 , Vegfa , Vegfc
atrial fibrillationCav1 , Flt1 , Hif1a , Nos3 , Pak2 , Ptk2 , Vegfa
atrial heart septal defect 1Ptpn11
atrophic gastritisPtpn11
AtrophyMapk3
attention deficit hyperactivity disorderVegfa
autism spectrum disorderCtnnb1 , Flt1 , Itgb3 , Map2k1 , Mapk1 , Mapk11 , Mapk12 , Mapk3 , Nos3 , Nrp2 , Pak2 , Ppp3ca , Prkcz , Ptpn11 , Ptpn6 , Vcl
autistic disorderCcl2 , Hras , Itgb3 , Mapk3 , Mapkapk2 , Nedd4 , Nrp2 , Pak2 , Pla2g4a , Pla2g6 , Prkcb , Ptgs2 , Ptk2 , Vegfd
autoimmune disease of gastrointestinal tractNfat5
autoimmune hepatitisCcl2 , Hras , Vegfa
autoimmune lymphoproliferative syndromeNras
autoimmune lymphoproliferative syndrome type 3Prkcd
autoimmune lymphoproliferative syndrome type 4Kras , Nras
autoimmune thrombocytopenic purpuraItgb3
autoinflammation, antibody deficiency, and immune dysregulation syndromePlcg2
autosomal dominant centronuclear myopathyDnm2
autosomal dominant cerebellar ataxiaPrkcg
autosomal dominant distal hereditary motor neuronopathy 2Hspb1
autosomal dominant distal hereditary motor neuronopathy 3Hspb1
autosomal dominant dyskeratosis congenita 6Cdh5 , Nfat5 , Nfatc3
autosomal dominant intellectual developmental disorder 19Ctnnb1
autosomal dominant intellectual developmental disorder 31Ctnna1
autosomal dominant intellectual developmental disorder 48Rac1
autosomal dominant nonsyndromic deafness 58Ppp3r1
autosomal recessive Alport syndromeBraf
autosomal recessive limb-girdle muscular dystrophy type 2PRhoa
autosomal recessive nonsyndromic deafness 26Gab1
autosomal recessive polycystic kidney diseaseAkt1 , Pik3ca , Src
autosomal recessive spinocerebellar ataxia 14Prkcg
avian influenzaPtgs2
B-Cell Chronic Lymphocytic LeukemiaCbl , Plcg2 , Ptgs2
B-cell lymphomaNras , Ptgs2
B-lymphoblastic leukemia/lymphoma with hyperdiploidyCbl
background diabetic retinopathyFlt1
BacteremiaCcl2 , Mapkapk3
bacterial infectious diseaseCasp9
bacterial pneumoniaCcl2 , Itgb3 , Pgf
Bannayan-Riley-Ruvalcaba syndromePik3ca
Banti's SyndromeItgb3
Bardet-Biedl syndromeAkt3
Bardet-Biedl syndrome 16Akt3
Barrett's esophagusPtgs2
basal cell carcinomaCav1 , Pik3ca , Rock1
Beckwith-Wiedemann syndromeHras
Behcet's diseaseCcl2 , Nos3 , Vegfa
beta-mannosidosisPpp3ca
bile duct adenomaBraf
Binge DrinkingCcl2 , Pla2g4a , Pla2g6
bipolar disorderAkt1 , Ccl2 , Cdc42 , Ptgs2
bladder neck obstructionHif1a , Nos3 , Ptgs2
blindnessVegfa
blood platelet diseasePla2g4a
Bloom syndromeChp1 , Fes , Iqgap1 , Map2k1 , Nedd4 , Pla2g4b , Pla2g4e , Pla2g4f
bone diseasePtk2b
Bone FracturesPtgs2
Bone NeoplasmsPtgs2
Brain DeathMap2k6
brain edemaVegfa
brain gliomaKdr , Vegfa
Brain HypoxiaNos3
Brain Hypoxia-IschemiaCasp9 , Ccl2 , Hif1a , Kdr , Vegfa
brain infarctionHif1a
Brain InjuriesAkt1 , Bad , Ccl2 , Hspb1 , Kdr , Ppp3ca , Ptgs2 , Rhoa , Vegfa , Vegfb
brain ischemiaAkap1 , Akt1 , Bad , Casp9 , Cav1 , Ccl2 , Hif1a , Kdr , Map2k1 , Mapk1 , Mapk3 , Nos3 , Pgf , Pla2g4a , Prkaca , Prkca , Prkcd , Ptgs2 , Ptk2b , Src
Brain NeoplasmsHras , Iqgap1 , Nras , Pik3ca , Vegfa
Brain-Lung-Thyroid SyndromeEgln3 , Nfatc4
breast adenocarcinomaAkt1 , Kras , Pik3ca
breast angiosarcomaKdr , Pik3ca
breast cancerAkt1 , Bad , Casp9 , Cav1 , Flt1 , Grb2 , Kdr , Kras , Map2k1 , Map2k2 , Map2k3 , Mapk1 , Nos3 , Pgf , Pik3ca , Plcg1 , Prkaa1 , Ptk2b , Rac1 , Rhoa
Breast Cancer, FamilialAkt1 , Kras , Nos3 , Pik3ca , Pik3r3
breast carcinomaCav1 , Kdr , Pik3ca , Plcg1 , Rhoa , Vegfc
Breast NeoplasmsAkt1 , Akt2 , Arf1 , Braf , Cav1 , Cdh5 , Ctnna1 , Ctnnb1 , Flt1 , Hif1a , Hras , Hsp90aa1 , Kdr , Kras , Nos3 , Pak2 , Pdpk1 , Pik3ca , Pik3r1 , Pla2g4a , Prkca , Ptgs2 , Ptk2 , Raf1 , Src , Vegfa , Vegfb , Vegfc
Bronchial HyperreactivityCcl2 , Itgb3 , Nos3
bronchiolitis obliteransCcl2 , Nos3
bronchiolo-alveolar adenocarcinomaKras
bronchopulmonary dysplasiaCasp9 , Flt1 , Hif1a
bullous pemphigoidVegfa
Burkitt lymphomaPik3r1
BurnsBad , Fyn , Hif1a , Pla2g4a , Prkcd , Ptgs2
CachexiaPtgs2
Cafe-au-Lait SpotsPtpn11
Calcification of Aortic ValveAkt1 , Ptgs2
calcinosisCcl2 , Ctnnb1 , Ptpn6
cancerBraf , Ptpn11
cannabis abuseAkt1 , Calm1 , Calm2
capillary hemangiomaAkt3
Capillary Malformation-Arteriovenous Malformation 1Kras , Pik3ca
CarcinogenesisAkt1 , Braf , Cav1 , Kras
carcinomaCdc42 , Hif1a , Hras , Kras , Pik3r1 , Ptgs2 , Rhoa
Carcinoma, Lewis LungMapk14
cardiac arrestAkt1
Cardiac ArrhythmiasPtgs2
Cardiac FibrosisPrkaa2
Cardioacrofacial Dysplasia 1Prkaca
cardiofaciocutaneous syndromeBraf , Hras , Kras , Map2k1 , Map2k2 , Ptpn11
cardiofaciocutaneous syndrome 1Braf , Kras , Map2k1 , Map2k2
cardiofaciocutaneous syndrome 2Kras
cardiofaciocutaneous syndrome 3Map2k1
cardiofaciocutaneous syndrome 4Map2k2
CardiomegalyAkt1 , Bad , Cav1 , Hif1a , Map2k6 , Mapk1 , Nos3 , Ppp3ca , Prkaa2 , Prkca , Prkcb , Prkcd , Prkcz , Rac1 , Raf1 , Rhoa , Src , Vegfa
cardiomyopathyAkt1 , Braf , Ccl2 , Kras , Mapk1 , Mapk11 , Mapk14 , Mapk3 , Nos3 , Prkaa2 , Ptgs2 , Ptpn11 , Vcl , Vegfa
CardiotoxicityCcl2 , Nos3 , Prkaa2 , Rac1
Cardiovascular AbnormalitiesMap2k1 , Pik3ca , Ptpn11
cardiovascular system diseaseCcl2 , Nos3 , Ptgs2
carnitine-acylcarnitine translocase deficiencyRhoa
carotid artery diseaseCcl2 , Pgf
Carotid Artery InjuriesCbl , Ccl2 , Itgav , Itgb3 , Nos3 , Ptpn11
carotid artery thrombosisItgb3
carotid stenosisItgb3
Carpenter syndrome 2Akt2 , Egln2
Carrington SyndromeCcl2
CatalepsyFyn
cataractCasp9 , Map2k1
cataract 5 multiple typesCdh5
catecholaminergic polymorphic ventricular tachycardiaCalm1
catecholaminergic polymorphic ventricular tachycardia 1Calm1
catecholaminergic polymorphic ventricular tachycardia 4Calm1
CD3epsilon deficiencyCbl
Cecal NeoplasmsCtnnb1 , Kras
central sleep apneaNos3
centronuclear myopathyDnm2
centronuclear myopathy 1Dnm2
centronuclear myopathy X-linkedDnm2
cerebellar ataxiaPrkcg
cerebellar hypoplasiaPla2g6
cerebral cavernous malformationFlt1 , Kdr
Cerebral Cavernous Malformation 4Pik3ca
Cerebral HemorrhageCasp9 , Flt1 , Itgav , Itgb3 , Kdr , Ptgs2 , Vegfa
cerebral infarctionCcl2 , Hif1a , Nos3
cerebral malariaPrkaa2
cervical cancerMap2k3 , Map2k6 , Nras , Ptk2 , Ptpn11 , Ptpn6
cervix carcinomaPtk2
cervix uteri carcinoma in situCtnna1 , Ptgs2 , Vegfa
Chagas diseaseCcl2
Chanarin-Dorfman syndromeHras
Charcot-Marie-Tooth diseaseArf1 , Dnm2 , Hspb1
Charcot-Marie-Tooth disease axonal type 2FHspb1
Charcot-Marie-Tooth disease axonal type 2OAkt1 , Hsp90aa1
Charcot-Marie-Tooth disease dominant intermediate BDnm2
Charcot-Marie-Tooth disease dominant intermediate CHspb1 , Pik3r3
Charcot-Marie-Tooth disease intermediate typeDnm2
Charcot-Marie-Tooth disease type 2Hspb1 , Pik3cd , Sh2d2a
Charcot-Marie-Tooth disease type 4Hspb1
Charcot-Marie-Tooth Disease, Dominant Intermediate 1Dnm2
Chemical and Drug Induced Liver InjuryBad , Casp9 , Ccl2 , Ctnnb1 , Flt1 , Nfatc4 , Prkaa1 , Prkcd , Ptgs2 , Vegfa
Child Behavior DisordersNos3
childhood pilocytic astrocytomaMapk1
Chlamydia pneumoniaPik3cd
cholangiocarcinomaBraf , Hif1a , Kras , Ppp3ca , Prkaca , Ptgs2 , Vegfa
cholangitisCcl2 , Nras
cholecystolithiasisPla2g2a
cholestasisMapk13 , Mapk14 , Nos3 , Prkaa1
cholesteatomaVegfa
cholesteatoma of middle earHif1a , Vegfa
chondromaPtpn11
chordoid gliomaPrkca
Choroidal NeovascularizationCcl2 , Flt1 , Hif1a , Itgav , Kdr , Vegfa , Vegfb
chromosome 11 partial duplication syndromeCbl
chromosome 16p11.2 deletion syndrome, 220-kbMapk3
chromosome 16p11.2 deletion syndrome, 593-kbMapk3
chromosome 16p11.2 duplication syndromeMapk3
Chromosome 16q12 Duplication SyndromeCdh5 , Nfat5 , Nfatc3
chromosome 16q22 deletion syndromePlcg2
chromosome 1p36 deletion syndromeCasp9 , Pik3cd , Pla2g2a , Pla2g2c , Pla2g2d , Pla2g2f , Pla2g5 , Prkcz
chromosome 22q11.2 deletion syndrome, distalMapk1
chromosome 22q13 duplication syndromeMapk11 , Mapk12
chromosome 3q29 microdeletion syndromePak2
Chromosome 7q11.23 Deletion Syndrome, Distal, 1.2-MBHspb1
Chronic BronchitisVegfa
Chronic Cerebral HypoperfusionHif1a , Mapk14 , Nos3 , Src
chronic fatigue syndromeVegfa
Chronic Hepatitis BCcl2
Chronic Hepatitis CCcl2
Chronic Intermittent HypoxiaCcl2 , Hif1a , Vegfa
chronic kidney diseaseNos3
chronic myelogenous leukemia, BCR-ABL1 positiveKras , Nras
chronic myeloid leukemiaAkt1 , Mapk14 , Vegfa
chronic myelomonocytic leukemiaNras
chronic obstructive pulmonary diseaseCcl2 , Flt1 , Hif1a , Kdr , Nos3 , Ptgs2 , Vegfa
Chronic PancreatitisBad
Chronic PeriodontitisCcl2 , Rac2
Chronic Relapsing Experimental Autoimmune EncephalomyelitisCcl2
Chronic Tubulointerstitial NephropathyCcl2
Churg-Strauss syndromeVtn
CLAPO SyndromePik3ca
clear cell renal cell carcinomaEgln3 , Flt4 , Vegfa
cleft lipNos3
cleft palateCdc42 , Nos3
CLOVES syndromePik3ca , Pik3r1
cocaine abuseMapk1 , Mapk3
cocaine dependenceMapk1 , Mapk3
Cocaine-Related DisordersCalm1 , Calm2 , Fyn , Mapk1 , Mapk3 , Rhoa
cognitive disorderMapk14 , Ptgs2
Cognitive DysfunctionHsp90aa1
colitisCcl2 , Kdr , Nos3 , Pgf , Pla2g2a , Ptgs2 , Src
Colitis-Associated NeoplasmsMapk14
colon adenocarcinomaCtnnb1 , Mapk1 , Mapk3 , Pik3ca , Pik3r3 , Rac1 , Src , Vegfc
colon adenomaRac1
colon cancerAkt1 , Akt3 , Bad , Ccl2 , Hsp90aa1 , Map2k3 , Mapk1 , Mapk14 , Pik3r2 , Pik3r5 , Plcg1 , Prkaa1 , Src , Vegfa
colon carcinomaAkt1 , Braf , Ctnnb1 , Flt1 , Flt4 , Kdr , Nras , Pik3ca , Ptprj , Src , Vegfa
Colonic NeoplasmsCcl2 , Ctnnb1 , Hif1a , Hspb1 , Kdr , Kras , Map2k6 , Pik3r1 , Pik3r2 , Ptgs2 , Src , Vegfa
colorectal adenocarcinomaBraf , Kdr , Mapk1 , Mapk3 , Rac1 , Raf1
colorectal adenomaRaf1
colorectal cancerAkt1 , Akt2 , Braf , Casp9 , Cbl , Chp1 , Ctnna1 , Ctnnb1 , Flt4 , Hif1a , Iqgap1 , Kdr , Kras , Map2k1 , Map2k2 , Mapk14 , Nedd4 , Nras , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pla2g2a , Pla2g4b , Pla2g4e , Pla2g4f , Plcg1 , Ptprj , Rac1 , Rhoa , Src , Vegfa
colorectal carcinomaItgb3 , Mapk14 , Pik3ca , Rac1 , Src
Colorectal NeoplasmsAkt1 , Braf , Cdh5 , Ctnnb1 , Kdr , Kras , Mapk1 , Mapk3 , Nras , Pik3ca , Pik3r3 , Pla2g2a , Prkcb , Ptgs2 , Ptprj , Src
complex cortical dysplasia with other brain malformationsAkt3 , Hras , Pik3ca
congenital diaphragmatic herniaCbl , Ccl2 , Nos3 , Rhoa , Vegfa
congenital disorder of glycosylationSrc
congenital disorder of glycosylation IgMapk11 , Mapk12
congenital disorder of glycosylation IjCbl
congenital disorder of glycosylation IrCdc42 , Pla2g2a , Pla2g2c , Pla2g2d , Pla2g2f , Pla2g5
congenital disorder of glycosylation type IIkKdr
congenital fibrosis of the extraocular musclesCtnna1 , Hras
congenital generalized lipodystrophy type 3Cav1
Congenital Heart Defects, Multiple Types, 7Flt4
congenital heart diseaseHif1a , Mapk1 , Vegfa
congenital hypoplastic anemiaAkt2 , Egln2
congenital muscular dystrophy-dystroglycanopathy type A8Ctnnb1
congenital myasthenic syndrome 13Cbl
congenital myasthenic syndrome 8Prkcz
congenital myopathy 5Cbl
Congenital Myopathy with Excess of Muscle SpindlesHras
congenital structural myopathyDnm2
congestive heart failureCbl , Ccl2 , Hif1a , Hspb1 , Map2k1 , Nos3 , Pdpk1 , Pgf , Prkaca , Prkca , Prkcb , Ptgs2 , Rac1 , Vcl , Vegfa
Conotruncal Cardiac DefectsPpp3cc
contact dermatitisCcl2 , Hsp90aa1 , Hspb1 , Kdr , Vegfa
ContusionsCcl2
corneal neovascularizationFlt1 , Itgav , Kdr , Vegfa
coronary artery diseaseAkt1 , Ccl2 , Cdh5 , Fes , Nos3 , Ptgs2 , Vegfa , Vtn
Coronary Artery Disease, Development of, in HIVCcl2
coronary artery vasospasmNos3
Coronary DiseaseFlt1 , Itgb3 , Kdr , Vegfa
coronary restenosisMapk1
coronary stenosisItgav
coronary thrombosisItgb3
Coronavirus infectious diseaseCcl2 , Mapk1 , Mapk3
coronin-1A deficiencyMapk3
Costello syndromeBraf , Hras , Kras , Map2k1 , Map2k2 , Ptpn11
CoughPtgs2
COVID-19Akt3 , Calm2 , Ccl2 , Flt1 , Grb10 , Myof , Nrp1 , Ptgs2 , Sh2d2a , Vegfa
Cowden syndromePik3ca
Cowden syndrome 5Pik3ca
Cowden syndrome 6Akt1
Craniofacial AbnormalitiesCtnnb1 , Rhoa
craniopharyngiomaBraf , Ctnnb1
craniosynostosisPtpn11
craniosynostosis 1Akt2 , Egln2
Craniosynostosis Syndrome, Autosomal RecessiveCtnna1
crescentic glomerulonephritisCcl2
Creutzfeldt-Jakob diseasePtgs2
Crohn's diseaseCcl2 , Kdr , Pgf , Ptgs2 , Vegfa , Vtn
Cryopyrin-Associated Periodic SyndromesPlcg2
cryptococcosisCcl2
cryptorchidismCbl , Ptgs2
Currarino syndromePik3ca
cutaneous leishmaniasisCcl2 , Pik3cd
cutaneous Paget's diseasePik3ca
cystic fibrosisCav1 , Ccl2 , Nos3 , Ptgs2
cystic kidney diseaseDnm2
cystitisKdr , Ptgs2
D-2-hydroxyglutaric aciduria 2Fes , Iqgap1
Dandy-Walker syndromeBraf
decubitus ulcerHif1a , Kdr , Vegfa
Delayed HypersensitivityCcl2
delta beta-thalassemiaHras
demyelinating diseaseMapk1 , Ptgs2
depressive disorderMapk1 , Pla2g2a , Ptgs2
Dermal FibrosisCav1
dermatitisPla2g4a
dermatitis herpetiformisVegfa
desmoid tumorCtnnb1
developmental and epileptic encephalopathyHras , Mapkapk3 , Pik3r3
developmental and epileptic encephalopathy 1Pdpk1 , Plcg2
developmental and epileptic encephalopathy 21Ptpn6
developmental and epileptic encephalopathy 54Akt3
developmental and epileptic encephalopathy 91Ppp3ca
Developmental DisabilitiesAkt3 , Braf , Cbl , Ctnnb1 , Mapk3 , Pik3ca , Ptpn11 , Rac1
Developmental DiseaseCtnnb1 , Ppp3ca , Rac1
Diabetes ComplicationsCasp9 , Hif1a , Prkaa1 , Vegfa
diabetes mellitusCav1 , Ptgs2 , Rac1
diabetic angiopathyCcl2 , Nos3 , Ptk2b , Vegfa
Diabetic CardiomyopathiesAkt1 , Bad , Casp9 , Ctnnb1 , Mapk1 , Mapk3 , Nos3 , Pik3ca
Diabetic CystopathyBad
Diabetic FootHif1a
Diabetic GastroparesisNos3
Diabetic NephropathiesCasp9 , Cav1 , Ccl2 , Flt1 , Hif1a , Hspb1 , Kdr , Mapk1 , Mapk14 , Nos3 , Pgf , Prkcb , Ptgs2 , Rhoa , Vegfa , Vtn
diabetic neuropathyBad , Cav1 , Mapk14 , Pgf , Ptgs2 , Vegfa
diabetic retinopathyAkt1 , Casp9 , Ccl2 , Flt1 , Hif1a , Hras , Itgb3 , Nos3 , Nrp1 , Pgf , Vegfa , Vtn
Diamond-Blackfan anemiaAkt2 , Egln2
diaphragmatic eventrationPik3ca
Diaphragmatic HerniaNos3
diffuse large B-cell lymphomaBraf , Pdpk1 , Pik3ca , Pik3cb , Pik3cd
diffuse sclerodermaCav1 , Kdr
DiGeorge syndromeMapk1 , Vegfa
dilated cardiomyopathyBraf , Casp9 , Ctnnb1 , Egln1 , Kras , Mapk3 , Nfatc4 , Pgf , Ppp3ca , Ppp3r1 , Prkca , Prkcb , Ptpn11 , Rac1 , Raf1 , Vcl
dilated cardiomyopathy 1ANfatc2
dilated cardiomyopathy 1BVcl
dilated cardiomyopathy 1LLPrkcz
dilated cardiomyopathy 1NNRaf1
dilated cardiomyopathy 1SVcl
dilated cardiomyopathy 1WVcl
Dilated Cardiomyopathy with Left Ventricular NoncompactionCbl , Raf1 , Vcl
disease of cellular proliferationKras , Nos3 , Ptgs2 , Vegfa
disease of metabolismPtpn11
Disease ProgressionCtnnb1 , Flt1 , Hif1a , Hras , Kras , Pik3ca , Prkab1 , Rac2 , Vegfb
Down syndromePik3ca
Drug-Induced EnteropathyNos3
Drug-Related Side Effects and Adverse ReactionsCcl2 , Mapk14 , Ptgs2 , Vegfa
Duane retraction syndromePtpn11
Duchenne muscular dystrophyCcl2 , Pla2g6
Ductal CarcinomaHif1a , Hsp90aa1
ductal carcinoma in situFlt1 , Hif1a , Pak2 , Prkca , Ptgs2 , Ptk2 , Src , Vegfa
duodenal ulcerPla2g4a , Ptgs2 , Vegfa
DwarfismCbl , Map2k2 , Mapk1 , Ptpn11
dysembryoplastic neuroepithelial tumorBraf
dysplastic nevus syndromeBraf
dystonia 12Pla2g6
early infantile epileptic encephalopathyHras , Mapkapk3 , Pik3r3
early-onset epilepsyCbl
ectodermal dysplasiaRhoa
ECTODERMAL DYSPLASIA WITH FACIAL DYSMORPHISM AND ACRAL, OCULAR, AND BRAIN ANOMALIESRhoa
EdemaCasp9 , Map2k6 , Ptgs2
Ehlers-Danlos syndrome spondylodysplastic type 2Prkcz
embryonal rhabdomyosarcomaPtpn11
Emery-Dreifuss muscular dystrophyPla2g6 , Rac2
Encephalocraniocutaneous LipomatosisKras
end stage renal diseaseCcl2 , Itgb3 , Nos3 , Pgf , Ptgs2
endodermal sinus tumorCtnnb1
endometrial adenocarcinomaKras , Mapk1 , Mapk3 , Pik3r1
endometrial cancerAkt2 , Bad , Pik3cb , Pik3cd , Pik3r1
endometrial carcinomaBraf , Grb2 , Hras , Kras , Mapk1 , Mapk3 , Nos3 , Pik3ca , Pik3r1 , Prkca , Ptk2
endometrial hyperplasiaKras , Ptk2
Endometrial Hyperplasia without AtypiaKras
Endometrial Intraepithelial NeoplasiaCtnnb1 , Kras
Endometrial NeoplasmsCcl2 , Ctnna1 , Ctnnb1 , Flt1 , Kdr , Kras , Mapk3 , Pik3ca , Pik3cb , Ptgs2 , Vegfa
Endometrioid CarcinomasCtnnb1 , Kdr , Kras , Mapk1 , Mapk3
endometriosisCcl2 , Ctnnb1 , Kdr , Kras , Nrp1 , Pla2g2a , Ptgs2 , Ptk2 , Vegfa
endometritisCasp9
endomyocardial fibrosisCcl2
EndotoxemiaAkt1 , Casp9 , Ccl2 , Itgb3 , Mapk14 , Nos3 , Pgf , Prkaa1 , Ptgs2
Endotoxin-Induced UveitisCcl2
epidermal nevusHras , Kras , Nras , Pik3ca
epilepsyAkt1 , Pdpk1 , Pgf , Pik3r2 , Pla2g6 , Ppp3ca
episodic ataxia type 2Dnm2
Episodic Kinesigenic DyskinesiaMapk3
episodic kinesigenic dyskinesia 1Mapk3
erythema multiformeVegfa
esophageal cancerAkt1 , Ctnna1 , Pik3ca
esophageal carcinomaAkt1 , Hras , Pik3ca
Esophageal NeoplasmsKdr , Nos3 , Ptgs2
esophagitisPtgs2
esophagus adenocarcinomaKdr , Nos3 , Pik3ca , Ptgs2
esophagus squamous cell carcinomaAkt1 , Fes , Hif1a , Ptgs2
essential hypertensionNos3
estrogen-receptor positive breast cancerPik3ca
exfoliation syndromeCav1
Experimental ArthritisAkt1 , Cbl , Ccl2 , Cdc42 , Flt1 , Hif1a , Itgb3 , Nos3 , Nras , Pgf , Pik3cd , Ptgs2 , Vegfa
Experimental Autoimmune EncephalomyelitisCasp9 , Ccl2 , Flt1 , Kdr , Prkaa1 , Ptgs2 , Rhoa , Vegfa
Experimental Autoimmune MyocarditisCasp9 , Cav1 , Ccl2
Experimental Autoimmune NeuritisCav1 , Hif1a , Ptgs2 , Rhoa
Experimental Autoimmune OrchitisCcl2
Experimental Autoimmune UveitisCcl2
Experimental Autoimmune UveoretinitisCcl2
Experimental ColitisAkt1 , Kdr , Mapk1 , Mapk3 , Vegfa
Experimental Diabetes MellitusAkt1 , Bad , Casp9 , Cav1 , Ccl2 , Flt1 , Hif1a , Hras , Hsp90aa1 , Itgb3 , Kdr , Map2k3 , Map2k6 , Mapk1 , Mapk3 , Nos3 , Nrp1 , Pgf , Pik3r1 , Plcg1 , Prkaa2 , Prkca , Prkcb , Prkcd , Ptgs2 , Rhoa , Vegfa , Vegfb
Experimental LeukemiaCbl , Nras , Ptpn11
Experimental Liver CirrhosisAkt1 , Cav1 , Ccl2 , Cdh5 , Fyn , Gab1 , Iqgap1 , Itgb3 , Mapk1 , Mapk3 , Nos3 , Pgf , Pla2g12a , Pla2g4a , Prkcb , Prkcd , Ptgs2 , Ptk2 , Rac2 , Rhoa , Vegfa
Experimental Liver NeoplasmsCtnnb1 , Hras , Kdr , Kras , Map2k1 , Mapk1 , Mapk3 , Nras
Experimental Mammary NeoplasmsAkt1 , Akt2 , Bad , Casp9 , Cav1 , Cdc42 , Ctnnb1 , Hif1a , Hras , Itgb3 , Kdr , Map2k3 , Mapk1 , Mapk3 , Pik3r1 , Ptgs2 , Ptk2 , Vegfa
Experimental MelanomaBraf , Pxn
Experimental NeoplasmsBraf , Ctnnb1 , Hif1a , Hras , Itgav , Kras , Nras , Vegfa
Experimental Radiation InjuriesCasp9 , Hif1a , Mapk1 , Mapk3 , Ptgs2
Experimental SarcomaKras , Nras
Experimental SeizuresBad , Ptgs2 , Vtn
extrahepatic bile duct adenocarcinomaRac1
extrahepatic cholestasisMapk1 , Mapk14 , Mapk3 , Nos3
extrinsic allergic alveolitisVegfa
exudative vitreoretinopathyCdh5 , Ctnnb1
exudative vitreoretinopathy 1Ctnnb1
exudative vitreoretinopathy 7Ctnnb1
Eye NeoplasmsCcl2 , Kdr
Facial AsymmetryPik3ca
Failure to ThrivePtpn11
familial adenomatous polyposisAkt1 , Plcg1 , Ptgs2
familial adenomatous polyposis 1Ctnna1
familial adult myoclonic epilepsy 5Mapkapk2
Familial Atrial Fibrillation 14Cbl
familial benign fleck retinaPla2g5
familial cold autoinflammatory syndromePlcg2
familial cold autoinflammatory syndrome 2Prkcg
familial cold autoinflammatory syndrome 3Plcg2
familial erythrocytosis 3Egln1
familial hypercholesterolemiaDnm2
familial hyperlipidemiaCcl2 , Nos3
familial hypertrophic cardiomyopathyCalm3 , Raf1 , Vcl
familial melanomaBraf
familial multiple nevi flammeiPik3ca
Familial Pancreatic CarcinomaKras
familial partial lipodystrophyAkt2 , Cav1
Familial Partial Lipodystrophy Type 7Cav1
Familial Prostate CancerMap2k1
familial temporal lobe epilepsy 1Myof
Familial Ventricular TachycardiaCalm1
Fanconi anemiaVegfd
Febrile NeutropeniaCcl2
female breast cancerFes
Female InfertilityHsp90ab1 , Mapk1 , Mapk3
Femur Head NecrosisHif1a , Nos3
fetal alcohol syndromeRhoa
Fetal DiseasesPrkcb
Fetal Growth RetardationNos3 , Ptgs2 , Ptpn11
FeverHspb1 , Pla2g4a , Plcg2 , Prkcd , Ptgs2
fibrillary astrocytomaKras
fibrolamellar carcinomaCtnnb1 , Prkaca
fibromyalgiaCcl2
fibrosarcomaCdc42
FibrosisAkt1 , Ctnnb1 , Ptgs2 , Rhoa , Sphk1
focal epilepsyNras , Plcg1 , Src
focal segmental glomerulosclerosisCasp9 , Hspb1 , Itgb3 , Ppp3ca , Ppp3cb
focal segmental glomerulosclerosis 5Akt1
Follicular Thyroid CancerBraf , Hras , Nras
follicular thyroid carcinomaHras , Kras , Nras
Frontotemporal Lobar DegenerationHsp90aa1
fructose-1,6-bisphosphatase deficiencyPpp3r2
fundus dystrophyCtnna1 , Mapkapk3
fungal infectious diseaseCcl2
Funnel ChestPtpn11
gallbladder cancerBraf , Ctnnb1 , Kras , Pik3ca
gallbladder carcinomaRac1
Gallbladder NeoplasmsKras , Ptgs2
gangliogliomaBraf
gastric adenocarcinomaBraf , Hras , Mapk14 , Nras , Pik3ca , Rac1
gastric ulcerBad , Mapk1 , Mapk3 , Nos3 , Ptgs2 , Vegfa
gastritisCcl2 , Ptgs2
gastroesophageal reflux diseasePla2g2a , Ptgs2
Gastrointestinal NeoplasmsPik3ca
gastrointestinal stromal tumorAkt3 , Arf1 , Braf , Ctnna1 , Egln1 , Kdr , Kras , Mapkapk2 , Pla2g4a , Ptgs2 , Sh2d2a
Gastrointestinal Ulceration, Recurrent, with Dysfunctional PlateletsPla2g4a
generalized epilepsyPpp3ca
genetic diseaseAkt1 , Akt2 , Akt3 , Arf1 , Braf , Calm2 , Cav1 , Cbl , Cdc42 , Ctnnb1 , Dnm2 , Egln1 , Egln2 , Flt4 , Hras , Hspb1 , Itgb3 , Kras , Map2k1 , Mapk1 , Nrp2 , Pik3ca , Pik3cd , Pik3r1 , Pik3r2 , Pla2g6 , Plcg2 , Ppp3ca , Prkcd , Prkcg , Ptpn11 , Rac1 , Rac2 , Raf1 , Rhoa , Vegfc
Genetic Predisposition to DiseasePpp3cc
Genitopatellar SyndromeVcl
Geographic AtrophyCcl2
Germ Cell and Embryonal NeoplasmsRhoa , Rock1
germinomaBraf
gestational diabetesCcl2
gingivitisVegfa
Glanzmann Thrombasthenia 1Itgb3
Glanzmann Thrombasthenia 2Itgb3
Glanzmann's thrombastheniaItgb3
glaucomaBad , Ptpn11 , Vegfa
glioblastomaAkt1 , Akt3 , Hif1a , Hras , Kdr , Kras , Map2k2 , Map2k3 , Nras , Pgf , Pik3ca , Pik3cb , Pik3cd , Ptgs2 , Ptk2 , Vegfa
gliosarcomaCcl2 , Ptgs2 , Vegfa
GliosisItgb3 , Mapk1 , Mapk3
glomerulonephritisCcl2 , Itgb3 , Mapk1 , Ptk2b , Vegfa
Glomus Tympanicum TumorVegfa
glucose intolerancePik3r1 , Prkaa1 , Prkaa2
glutaric acidemia IDnm2
glycine encephalopathyRhoa
glycogen storage disease IIPik3ca
glycogen storage disease VHif1a
glycogen storage disease VIIHif1a
Glycogen Storage Disease XIIMapk3
GM1 gangliosidosisCtnnb1
GM1 gangliosidosis type 1Ctnnb1
Goldberg-Shprintzen syndromePrkcz
Graft Occlusion, VascularNos3
graft-versus-host diseaseVegfa
granulomatosis with polyangiitisVtn
Granulomatous Interstitial NephritisCcl2
Granulomatous VasculitisCcl2
granulosa cell tumorCtnnb1 , Ptgs2 , Vegfa
Graves ophthalmopathyCcl2 , Ptgs2
Graves' diseaseItgb3 , Vegfa
Growth DisordersCbl , Pik3ca
growth hormone secreting pituitary adenomaPtgs2
Guillain-Barre syndromeCcl2
Haemophilus InfectionsPtpn11
hairy cell leukemiaMap2k1
Hand-Foot SyndromeKdr
Hantavirus hemorrhagic fever with renal syndromeItgb3
Hantavirus InfectionsItgb3
Head and Neck NeoplasmsMapk1 , Mapk3 , Vegfa
head and neck squamous cell carcinomaAkt1 , Braf , Ctnnb1 , Hras , Pik3ca , Ptgs2
Hearing Loss, Noise-InducedCcl2 , Hif1a , Src
heart diseaseCasp9 , Mapk14 , Rac2 , Vegfa
heart valve diseaseCcl2 , Ptpn6
Helicobacter InfectionsGab1 , Prkaa1 , Ptpn11
hemangioblastomaHif1a
hemangiopericytomaKdr
hemarthrosisCcl2
Hematologic NeoplasmsCbl
Hemifacial MyohyperplasiaPik3ca
HemimegalencephalyPik3ca
hemolytic-uremic syndromeCcl2
HemorrhageCav1 , Itgb3 , Vegfa
hemorrhagic diseaseItgb3 , Ptpn11
Hemorrhagic ShockBad , Mapk1 , Nos3
hepatic encephalopathyCcl2 , Hif1a
Hepatic InsufficiencyMapk14 , Nos3
hepatitis BCtnnb1
hepatoblastomaCtnnb1 , Kdr
hepatocellular adenomaCtnnb1 , Hras , Kras , Ptpn11
hepatocellular carcinomaAkt1 , Akt2 , Braf , Casp9 , Cbl , Ccl2 , Ctnnb1 , Fes , Hif1a , Hras , Hspb1 , Iqgap1 , Kdr , Kras , Map2k2 , Mapk1 , Mapk14 , Nras , Nrp1 , Pik3ca , Pik3cb , Pik3r1 , Pik3r2 , Pik3r3 , Plcg1 , Ptgs2 , Ptk2 , Rac1 , Src , Vegfa , Vegfc
HepatomegalyAkt1 , Mapk14 , Nos3
hepatopulmonary syndromeNos3 , Vegfa
Hereditary Angioedema 7Myof
hereditary ataxiaPrkcg
hereditary breast ovarian cancer syndromeAkap1 , Ctnna1 , Itgb3 , Kras , Plcg1 , Raf1
hereditary desmoid diseaseCtnnb1
hereditary diffuse gastric cancerCtnna1 , Kras
hereditary fructose intolerance syndromePpp3r2
hereditary lymphedemaFlt4 , Vegfc
hereditary lymphedema IFlt4
hereditary lymphedema IAFlt4
hereditary lymphedema IDVegfc
hereditary mixed polyposis syndrome 1Ctnna1
hereditary multiple exostosesPtpn11
Hereditary Neoplastic SyndromesAkt1 , Cbl , Ctnna1 , Egln1 , Hras , Pik3ca , Ptpn11 , Raf1
Hereditary PancreatitisCasp9
hereditary sensory neuropathy type 4Sh2d2a
hereditary spastic paraplegia 47Nras
heroin dependenceAkt1 , Ctnnb1
herpes simplexCcl2
herpes simplex virus keratitisCcl2 , Kdr
high grade gliomaAkt2 , Bad , Braf , Camkk2 , Cav1 , Hras , Kdr , Kras , Map2k1 , Mapk3 , Nos3 , Pik3ca , Pik3r3 , Prkca , Ptgs2 , Ptpn11 , Raf1 , Sphk1
High MyopiaKdr , Prkaa2
Hip FracturesItgb3
Hirschsprung Disease 1Nrp2
Hirschsprung's diseaseKdr , Nrp2 , Vcl
Hodgkin's lymphomaKras , Mapk1
Hot FlashesHif1a
human immunodeficiency virus infectious diseaseCcl2 , Cdc42 , Hsp90aa1 , Hsp90ab1 , Hspb1 , Pla2g2a , Ptgs2
Human InfluenzaCcl2 , Ptgs2
Huntington's diseaseCasp9 , Ppp3ca , Prkaa1 , Ptgs2
hydronephrosisPtgs2
hydrophthalmosFlt1 , Kdr
Hydrops FetalisFlt4 , Hras , Kras , Ptpn11
hyper IgE recurrent infection syndrome 1Itgb3
HyperalgesiaCcl2 , Hif1a , Map2k3 , Mapk1 , Mapk3 , Pla2g4a , Prkcb , Prkcg , Prkcz , Ptgs2 , Raf1 , Src
HypercholesterolemiaCasp9 , Vegfa
hyperekplexiaCtnnb1
HyperemiaEgln1 , Nos3 , Ptgs2
hyperglycemiaCbl , Ccl2 , Itgav , Nos3 , Pla2g4a , Prkcb , Prkcz , Ptgs2
hyperhomocysteinemiaCcl2
hyperinsulinismCcl2 , Nos3 , Prkcd
HyperoxaluriaCcl2
HyperoxiaNos3
Hyperphosphatemic Familial Tumoral Calcinosis 1Ptpn6
HyperplasiaAkt1 , Cav1 , Hif1a , Hspb1 , Pik3ca , Ptgs2 , Vegfa
hyperprolinemia type 2Cdc42 , Pla2g2a , Pla2g2c , Pla2g2d , Pla2g2f , Pla2g5
HypertelorismPik3ca
hypertensionAkt1 , Akt2 , Bad , Casp9 , Cav1 , Ccl2 , Egln1 , Hif1a , Itgav , Kdr , Kras , Nos3 , Pgf , Pik3r1 , Prkca , Prkcb , Prkcd , Ptgs2 , Ptk2 , Ptk2b , Ptprj , Rhoa , Src , Vegfa
Hypertension Resistant to Conventional TherapyNos3
HypertriglyceridemiaAkt1 , Nos3
hypertrophic cardiomyopathyBraf , Cav1 , Ctnnb1 , Hspb1 , Map2k2 , Ptpn11 , Raf1 , Vcl
hypertrophic cardiomyopathy 1Raf1 , Vcl
hypertrophic cardiomyopathy 15Vcl
hypertrophic cardiomyopathy 2Vcl
hypertrophic cardiomyopathy 4Braf
HypertrophyMapk1 , Mapk3
Hypoglossal Nerve InjuriesPrkaca
hypoglycemiaAkt2 , Pik3r1
hypoinsulinemic hypoglycemia with hemihypertrophyAkt2
Hypokalemic Periodic Paralysis, Type 1Mapkapk2
Hypophosphatemic RicketsHras
HypopigmentationRhoa
HypotensionMap2k2
HypothermiaPrkcd
hypothyroidismBad , Cav1 , Nos3
HypoxiaCcl2 , Nos3 , Pgf , Ptgs2
Idiopathic Generalized EpilepsyPdpk1 , Prkcz
idiopathic pulmonary fibrosisAkt1 , Hif1a , Ptgs2
idiopathic scoliosisPtpn11
IgA glomerulonephritisCcl2
IgA vasculitisCcl2
ileusNos3
IMMUNE DYSREGULATION, AUTOIMMUNITY, AND AUTOINFLAMMATIONPlcg1
immune system diseasePrkcb
Immunoblastic LymphadenopathyRhoa
immunodeficiency 132AAkt1 , Hsp90aa1
immunodeficiency 14Pik3cd , Pik3r1
immunodeficiency 16Prkcz
immunodeficiency 17Cbl
immunodeficiency 18Cbl
immunodeficiency 19Cbl
immunodeficiency 35Dnm2
immunodeficiency 36Pik3r1
immunodeficiency 38Prkcz
immunodeficiency 39Hras
immunodeficiency 42Sh2d2a
immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosisRac2
immunodeficiency 73b with defective neutrophil chemotaxis and lymphopeniaRac2
immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemiaRac2
imperforate anusCtnnb1
impotenceAkt1 , Bad , Kdr , Nos3 , Vegfa
in situ carcinomaAkt1 , Ctnnb1 , Ptgs2
Infantile Capillary HemangiomaFlt4 , Kdr , Vegfa
infantile Refsum diseaseVegfa
InfarctionHif1a
InflammationAkt1 , Ccl2 , Pgf , Pla2g4a , Ptgs2 , Vegfa
inflammatory bowel diseasePlcg2 , Ptgs2 , Vegfa
inflammatory bowel disease 28Cbl
Inflammatory Breast NeoplasmsCcl2
influenzaCcl2 , Ptpn11
inherited metabolic disorderPla2g4a
Insulin ResistanceAkt2 , Bad , Ccl2 , Mapk3 , Nos3 , Pik3r1 , Pla2g1b , Prkaa1 , Prkaa2 , Prkcb , Prkcd , Prkcz , Ptk2b
intellectual disabilityBad , Braf , Ctnnb1 , Hras , Kras , Mapk1 , Mapk11 , Mapk12 , Pgf , Pik3r2 , Ppp3r2 , Prkcg , Ptpn11 , Ptprj , Rock1 , Vegfb
intermediate coronary syndromeAkt1
intermittent claudicationBad
interstitial cystitisHif1a , Mapk14 , Vegfa
interstitial lung diseaseCcl2
interstitial nephritisCcl2
Intervertebral Disc DiseaseHif1a
Intervertebral Disc DisplacementAkt1 , Hif1a
Intestinal NeoplasmsCtnnb1 , Pla2g2a , Prkca , Prkcd
intestinal obstructionPtgs2
intestinal perforationNos3
Intestinal PolypsPtgs2
Intestinal Reperfusion InjuryCasp9 , Ccl2 , Nos3
Intimal HyperplasiaMapk1 , Nos3 , Nrp1
intracranial aneurysmCcl2 , Nos3 , Vegfa
Intracranial HemorrhagesHspb1 , Nos3
intracranial vasospasmCcl2
intrahepatic cholangiocarcinomaBraf , Hsp90aa1 , Hsp90ab1 , Kras
invasive aspergillosisCcl2
invasive ductal carcinomaAkt1 , Cav1 , Hif1a , Ptgs2 , Vegfc
invasive lobular carcinomaCtnna1 , Ctnnb1
Invasive Pulmonary AspergillosisCcl2 , Vegfa
inverted papillomaKdr , Vegfa
irritable bowel syndromeNos3
ischemiaAkt2 , Ccl2 , Flt1 , Itgav , Nos3 , Prkca , Ptk2 , Raf1
ischemic colitisVegfa
isolated microphthalmia 5Cbl
JOINT CONTRACTURES, OSTEOCHONDROMAS, AND B-CELL LYMPHOMANfatc2
Joubert syndrome 1Akap1
Joubert syndrome 25Prkcz
juvenile myelomonocytic leukemiaCbl , Kras , Nras , Ptpn11 , Rac2
juvenile rheumatoid arthritisKras , Mapk1 , Sh2d2a
Kabuki syndromePrkag1
Karak SyndromePla2g6
Kawasaki diseaseFlt1 , Vegfa
KeloidNedd4
keratoacanthomaPik3ca
keratoconusNfatc3 , Ppp3cc
kidney diseaseCasp9 , Ccl2 , Mapk1 , Ppp3ca , Ptgs2
kidney failureHif1a
Kidney NeoplasmsAkt1 , Braf , Flt1 , Kdr , Kras , Mapk1 , Mapk3 , Ptgs2 , Raf1
Kidney Reperfusion InjuryCcl2 , Egln1 , Egln3 , Hif1a , Nos3 , Src
Klatskin's tumorKras
Klippel-Feil syndrome 3Ptpn6
Klippel-Trenaunay syndromePik3ca
Knee OsteoarthritisCtnnb1 , Hsp90aa1
Knobloch SyndromePak2
Knobloch Syndrome Type IIPak2
Kuhnt-Junius degenerationCcl2 , Flt1 , Kdr , Nos3 , Vegfa
Langerhans-cell histiocytosisBraf
large cell carcinomaPrkca
large congenital melanocytic nevusHras , Nras
Laryngeal NeoplasmsPtgs2
Laryngeal PapillomatosisPtgs2
laryngeal squamous cell carcinomaPlcg1
larynx cancerVegfa
late-onset retinal degenerationPla2g5
LathyrismKdr
learning disabilityPtpn11 , Vegfa
Leber congenital amaurosisHras
Left Ventricular HypertrophyCtnnb1 , Mapk1 , Nfatc3 , Nfatc4 , Nos3 , Ppp3ca , Ppp3cb , Ppp3r1 , Prkca , Prkcb , Prkcd , Prkcz , Ptgs2 , Ptk2 , Ptk2b , Rac1 , Rhoa , Rock1
leiomyomaCav1 , Nos3 , Ptk2
leiomyosarcomaFlt1 , Ptgs2
lesion of sciatic nerveSrc
Lethal Congenital Contracture Syndrome 5Dnm2
lethal congenital glycogen storage disease of heartNos3
leukemiaBad , Nras , Prkcz , Ptpn11 , Sphk1
leukocyte adhesion deficiency 3Bad , Vegfb
LeukocytosisKras , Nras
LeukoencephalopathiesRhoa
Leydig cell tumorFlt1
limb ischemiaHif1a , Itgav , Nos3 , Vegfa
limited sclerodermaCav1 , Ccl2 , Kdr , Pgf
linear nevus sebaceous syndromeHras , Kras , Nras
lipodystrophyCcl2
listeriosisPik3cd
liver benign neoplasmMap2k3
liver cancerHras , Mapk14 , Pik3ca
liver carcinomaHras , Nras
liver cirrhosisCasp9 , Ccl2 , Ctnnb1 , Flt1 , Hif1a , Hras , Kdr , Mapk14 , Nos3 , Pgf , Ptgs2 , Vegfa , Vegfc , Vtn
liver diseaseCcl2 , Nrp1 , Rac1
Liver FailureVegfa
Liver InjuryHspb1
Liver MetastasisBraf , Ccl2 , Nras , Src , Vegfa
Liver NeoplasmsBraf , Ctnnb1 , Egln3 , Hras , Kras , Mapk14 , Raf1
Liver Reperfusion InjuryBad , Casp9 , Ccl2 , Nos3 , Vegfa
long QT syndromeBraf , Calm1 , Calm2 , Calm3 , Nos3 , Ptpn11 , Vcl
long QT syndrome 1Braf , Calm2 , Calm3 , Ptpn11
long QT syndrome 10Cbl
long QT syndrome 14Calm1
long QT syndrome 15Calm2
long QT syndrome 16Calm3
low tension glaucomaCav1
Lower Extremity Deep Vein ThrombosisCcl2
lung adenocarcinomaBraf , Ctnnb1 , Fes , Flt1 , Hras , Hspb1 , Kras , Map2k1 , Mapk14 , Pik3ca , Pik3r1 , Plcg1 , Ppp3ca , Ptprj , Rac1 , Raf1 , Src
lung cancerBraf , Ctnnb1 , Kras , Pik3ca , Plcg1 , Ptgs2 , Rac1
lung carcinomaBraf , Ctnna1 , Ctnnb1 , Kdr , Kras , Pik3ca
lung diseaseCcl2 , Hif1a , Itgb3 , Nos3 , Ptgs2 , Vegfa
Lung InjuryCcl2
lung metastasisItgav , Src
Lung NeoplasmsAkt1 , Braf , Cav1 , Ctnnb1 , Hras , Kdr , Kras , Map2k3 , Mapk1 , Mapk14 , Mapk3 , Pik3ca , Raf1
lung non-small cell carcinomaAkt1 , Akt3 , Bad , Braf , Casp9 , Cbl , Hif1a , Hras , Itgb3 , Kdr , Kras , Map2k1 , Map2k2 , Nras , Nrp1 , Pdpk1 , Pik3ca , Plcg1 , Prkaa1 , Prkcb , Ptgs2 , Pxn , Raf1 , Vegfa
Lung Reperfusion InjuryKras , Nos3
lung sarcomatoid carcinomaKras
lung small cell carcinomaPik3ca , Pik3r1 , Ptk2
lung squamous cell carcinomaBraf , Ctnnb1 , Hras , Kras , Map2k1 , Pik3ca , Ptk2 , Ptpn11 , Ptprj , Src
lupus nephritisCcl2
Lyme NeuroborreliosisCcl2
LymphangiectasisRaf1
lymphangioleiomyomatosisNos3 , Vegfd
lymphangiomaBraf , Flt4 , Kdr , Pik3ca
Lymphatic MetastasisBraf , Casp9 , Cav1 , Cbl , Ctnna1 , Ctnnb1 , Kdr , Nos3 , Pdpk1 , Pik3ca , Pik3cb , Ptgs2 , Ptk2 , Rhoa , Src , Vegfa , Vegfc , Vegfd
lymphedemaFlt4 , Pgf
lymphomaKras , Nras , Ptpn11 , Rac2
lymphopeniaCbl
lymphoproliferative syndromeSh2d2a
lymphoproliferative syndrome 2Ptpn6
Lynch syndromeCalm2 , Ctnna1 , Kras
lysinuric protein intoleranceNfatc4
MacrocephalyAkt3 , Pik3ca
Macrocephaly Mesodermal Hamartoma SpectrumAkt1
macular degenerationBad , Ccl2 , Flt1 , Kdr , Vegfa
macular retinal edemaCcl2 , Flt1 , Hif1a , Kdr , Nos3 , Vegfa
Maffucci syndromeHif1a
major depressive disorderCalm2
malariaMapkapk3
male infertilityCbl , Nos3
malignant astrocytomaAkt1 , Akt2 , Akt3 , Braf , Hif1a , Hras , Kras , Map2k3 , Ptpn11
malignant mesotheliomaCdh5 , Ctnnb1 , Raf1
malignant ovarian germ cell neoplasmCbl
Mandibular NeoplasmsBraf , Ctnnb1
mantle cell lymphomaCtnnb1 , Pik3cd
maple syrup urine diseaseAkt2 , Egln2
Marfanoid Mental Retardation Syndrome, AutosomalCdh5
maturity-onset diabetes of the young type 1Akt2
medulloblastomaCtnnb1 , Pik3ca
megacolonAkt3
Megalencephaly - Cutis Marmorata Telangiectatica CongenitaAkt3 , Pik3ca , Pik3r1 , Pik3r2
Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus SyndromeAkt3 , Pik3ca , Pik3r2
Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome 1Pik3r2
Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome 2Akt3
MegalodactylyPik3ca
melanomaBraf , Cav1 , Flt1 , Hras , Kdr , Map2k1 , Map2k2 , Mapk1 , Mapk14 , Nras , Pik3ca , Ptgs2 , Ptk2b , Rac1 , Rac2 , Vegfa , Vegfc
melorheostosisMap2k1
membranoproliferative glomerulonephritisCcl2
membranous glomerulonephritisRhoa
Memory DisordersAkt1 , Hif1a , Mapk1 , Mapk3 , Plcg1 , Sphk2 , Vegfa
meningiomaAkt1
metabolic dysfunction and alcohol associated liver diseaseAkt1 , Ccl2
metabolic dysfunction-associated steatohepatitisAkt1 , Ccl2
metabolic dysfunction-associated steatotic liver diseaseAkt1 , Ccl2 , Prkaca , Prkca , Prkcd , Ptgs2
Metabolic SyndromeCcl2 , Itgav , Map2k2 , Nos3 , Pla2g4a , Pla2g6 , Prkaa2 , Ptgs2 , Vegfa
metachondromatosisPtpn11
metachromatic leukodystrophyMapk11 , Mapk12
MetaplasiaCtnnb1
MHC class II deficiencySh2d2a
microcephalyCbl , Ptpn11
microcytic anemiaDnm2
Micronuclei, Chromosome-DefectiveHif1a
Microsatellite InstabilityBraf
microvillus inclusion diseaseCdc42
middle cerebral artery infarctionBad , Casp9 , Ccl2 , Hif1a , Mapk1 , Mapk3 , Prkcg , Sphk2 , Vegfa
Middle East respiratory syndromeCcl2
migraineMap2k2 , Nos3
mitral valve prolapseMap2k2
mixed fibrolamellar hepatocellular carcinomaPrkaca
morbid obesityHif1a
morphine dependenceMapk1 , Mapk3
morphine withdrawal syndromeBad , Fyn , Src
mosaic variegated aneuploidy syndrome 1Chp1
mouth diseasePtgs2
Mouth NeoplasmsCcl2 , Hras , Hspb1 , Kras , Nras , Pik3ca , Ptgs2 , Ptk2
multicentric Castleman diseaseMap2k2
Multiple AbnormalitiesCtnnb1 , Kras
multiple congenital anomalies-hypotonia-seizures syndrome 2Vegfd
multiple endocrine neoplasia type 1Bad , Vegfb
multiple intestinal atresiaCalm2
multiple mitochondrial dysfunctions syndrome 3Arf1
multiple myelomaBraf , Cbl , Ccl2 , Hras , Hspb1 , Kras , Nras , Pik3r2 , Vegfa
Multiple Organ FailureCcl2 , Mapk1
multiple sclerosisCav1 , Ccl2 , Hsp90ab1 , Rhoa , Sh2d2a
muscular atrophyAkt1 , Ctnnb1 , Hsp90ab1 , Kras , Nedd4
muscular diseasePrkcd
Mycoplasma pneumoniae pneumoniaFlt1
mycosis fungoidesHif1a
myelodysplastic syndromeCtnna1 , Itgb3 , Kras , Nras , Sphk1
myelofibrosisSrc
myeloid leukemiaVegfa
myeloid leukemia associated with Down SyndromeNras , Ptpn11
myeloid neoplasmCbl , Kras , Nras
myeloid sarcomaKras
myocardial infarctionAkt1 , Ccl2 , Egln1 , Egln3 , Flt1 , Hif1a , Itgb3 , Kdr , Mapk1 , Mapk14 , Nos3 , Pgf , Ptgs2 , Vegfa , Vegfb
Myocardial IschemiaCcl2 , Ctnnb1 , Hif1a , Itgav , Kdr , Map2k3 , Mapk14 , Nedd4 , Nos3 , Pgf , Pla2g2a , Ppp3r1 , Prkcd , Vegfa
Myocardial Reperfusion InjuryAkt1 , Akt2 , Bad , Casp9 , Cbl , Ccl2 , Egln1 , Hif1a , Map2k6 , Mapk1 , Mapk14 , Mapk3 , Nos3 , Prkaa2 , Prkcb , Prkcd , Ptgs2 , Rhoa , Vegfa
myocarditisCcl2 , Ptgs2
myoclonic dystonia 26Pla2g6 , Rac2
myoepitheliomaBraf
myofibrillar myopathyDnm2
myopathyDnm2
Nasal PolypsCcl2 , Kdr , Nos3 , Ptgs2 , Vegfa
nasopharynx carcinomaFlt1 , Kdr , Mapk14 , Rac1 , Src , Vegfa
NATURAL KILLER CELL ENTEROPATHYPik3cb
NecrosisCdc42
Nematode InfectionsPik3r1
NeointimaAkt1 , Flt1 , Iqgap1 , Ptk2b
Neonatal Alloimmune ThrombocytopeniaItgb3
Neonatal Hypoglycemia, Simulating Foetopathia DiabeticaAkt2
Neonatal SepsisPla2g2a
Neoplasm InvasivenessArf1 , Ccl2 , Ctnnb1 , Hif1a , Hras , Mapk1 , Mapk3 , Ptk2 , Rhoa , Src
Neoplasm MetastasisAkt2 , Braf , Cav1 , Ccl2 , Ctnnb1 , Flt1 , Hsp90aa1 , Itgb3 , Kdr , Kras , Mapk1 , Mapk3 , Nos3 , Pik3ca , Pik3r3 , Ptgs2 , Ptk2 , Pxn , Rac1 , Rhoa , Src , Vegfa
Neoplasm Recurrence, LocalPtgs2 , Vcl , Vegfa
Neoplastic Cell TransformationCtnnb1 , Hif1a , Hras , Kras , Ptk2 , Pxn , Rac1 , Vegfa
Neoplastic ProcessesHras
neovascular glaucomaVegfa
Neovascularization, PathologicKdr , Vegfa
nephritisCcl2 , Nos3 , Ptk2 , Ptk2b
nephroblastomaBraf , Ctnnb1 , Flt1 , Hif1a , Ptgs2 , Vegfc
nephrogenic diabetes insipidusPrkca
Nephrogenic Fibrosing DermopathyCav1
nephrotic syndromeNck1 , Nck2 , Ptgs2
Nerve DegenerationCtnnb1 , Mapk1 , Mapk3 , Vegfa
nervous system diseaseCasp9 , Nfatc2 , Ptgs2
Nervous System MalformationsCtnnb1 , Pla2g6
neural tube defectCcl2
NeuralgiaKdr , Nfatc4 , Src
neurilemmomaKdr
neuroaxonal dystrophyPla2g6
neuroblastomaHras , Kras , Nras , Ptpn11
Neurocutaneous MelanosisNras
Neurocutaneous SyndromesRhoa
neurodegeneration with brain iron accumulationPla2g6
neurodegeneration with brain iron accumulation 2APla2g6 , Rac2
neurodegeneration with brain iron accumulation 2BPla2g6
neurodegenerative diseasePla2g6
neurodevelopmental disorder with dysmorphic facies and distal limb anomaliesRac1
NEURODEVELOPMENTAL DISORDER WITH MICROCEPHALY, ARTHROGRYPOSIS, AND STRUCTURAL BRAIN ANOMALIESPik3ca
Neurodevelopmental DisordersAkt3 , Cbl , Ccl2 , Cdc42 , Ctnna1 , Ctnnb1 , Hsp90aa1 , Itgav , Mapk3 , Mapkapk2 , Nras , Nrp2 , Pik3cd , Pik3r1 , Pla2g4b , Prkaa1 , Prkaca , Prkcz , Ptpn11 , Ptpn6 , Vegfc , Vegfd
NEURODEVELOPMENTAL, JAW, EYE, AND DIGITAL SYNDROMEFbxw11
neuroendocrine tumorBraf
neurofibromaPtpn11
neurofibromatosis 1Vegfa
neurofibromatosis-Noonan syndromeMap2k2 , Ptpn11
neurofibrosarcomaKdr , Nras , Vegfa
Neurogenic InflammationPtgs2
neuronal ceroid lipofuscinosisHras , Map2k1
neuronal ceroid lipofuscinosis 6AMapk1 , Mapk3
neuropathyDnm2
NevusBraf , Pla2g6
newborn respiratory distress syndromeBraf , Vegfa
No-Reflow PhenomenonCdh5 , Ctnnb1
non-arteritic anterior ischemic optic neuropathyItgb3
non-Hodgkin lymphomaBraf
Nonseminomatous Germ Cell TumorBraf
Noonan Like SyndromeCbl , Cdc42 , Ptpn11
Noonan syndromeBraf , Cbl , Hras , Kras , Map2k1 , Map2k2 , Nras , Ptpn11 , Raf1
Noonan syndrome 1Braf , Cbl , Hras , Kras , Map2k1 , Map2k2 , Nras , Ptpn11 , Raf1
Noonan syndrome 13Mapk1
Noonan syndrome 3Hras , Kras , Ptpn11 , Raf1
Noonan syndrome 5Raf1
Noonan syndrome 6Nras
Noonan syndrome 7Braf
Noonan syndrome with multiple lentiginesBraf , Map2k2 , Ptpn11 , Raf1
Noonan syndrome with multiple lentigines 1Ptpn11
Noonan syndrome with multiple lentigines 2Raf1
Noonan syndrome with multiple lentigines 3Braf
Noonan Syndrome-Like Disorder with or without Juvenile Myelomonocytic LeukemiaCbl , Ptpn11
NSAID-EnteropathyCasp9
obesityAkap1 , Akt1 , Akt2 , Bad , Cav1 , Ccl2 , Hif1a , Mapk1 , Mapk3 , Nos3 , Pgf , Pik3r1 , Prkcb , Prkcd , Ptgs2 , Rhoa
obsessive-compulsive disorderHras
obstructive jaundiceCcl2
obstructive sleep apneaCcl2 , Nos3 , Ptgs2
occupational asthmaPla2g4a , Prkca , Ptgs2
oculoectodermal syndromeKras
olfactory neuroblastomaHif1a
oligospermiaNos3
Ollier diseaseHif1a , Ptpn11
open-angle glaucomaCav1 , Ptgs2
opiate dependenceAkt1 , Vegfa
Optic Nerve InjuriesRhoa
oral mucosa leukoplakiaPtgs2
oral squamous cell carcinomaCcl2 , Plcg1 , Vegfa
oral submucous fibrosisPtgs2
orchitisCcl2
osteoarthritisBad , Casp9 , Cav1 , Flt1 , Hif1a , Pik3r1 , Ptgs2
Osteoarthritis, ExperimentalFlt1 , Mapk3
osteochondrodysplasiaFlt1 , Kdr , Vegfa
OsteochondromaPtpn11
Osteopetrosis and Infantile Neuroaxonal DystrophyPla2g6
osteoporosisMapk14 , Vcl
osteosarcomaCbl , Vegfa
osteosclerosisCtnnb1
otitis mediaVegfa
Otitis Media with EffusionFlt1 , Kdr , Vegfa
ovarian cancerAkt1 , Ctnnb1 , Hif1a , Hras , Nos3 , Pik3ca , Prkca , Vegfc
ovarian carcinomaAkt2 , Cav1 , Map2k1 , Map2k6 , Ppp3ca , Prkca , Ptk2 , Raf1 , Rhoa , Vegfd
ovarian germ cell cancerCbl
ovarian hyperstimulation syndromeKdr , Vegfa
Ovarian NeoplasmsAkt1 , Akt2 , Braf , Camkk2 , Cav1 , Ctnna1 , Ctnnb1 , Flt1 , Hras , Kdr , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Pik3ca , Pik3r1 , Ptgs2 , Vegfa
ovary serous adenocarcinomaKras
overnutritionNos3
Oxygen-Induced RetinopathyCcl2 , Hif1a , Kdr , Vegfa
PainAkt1 , Ccl2 , Map2k2 , Nos3 , Ptgs2
Painful NeuropathyCcl2
pancreatic acinar cell adenocarcinomaBraf , Src
pancreatic adenocarcinomaAkt3 , Map2k1 , Mapk1 , Rac1 , Raf1 , Vegfc
pancreatic cancerAkt1 , Akt2 , Bad , Braf , Casp9 , Cdc42 , Ctnnb1 , Hif1a , Hspb1 , Kdr , Kras , Nrp1 , Ptgs2 , Vegfb
pancreatic carcinomaKdr , Kras , Raf1
pancreatic ductal adenocarcinomaPgf , Pik3r2 , Rac1 , Vegfd
pancreatic ductal carcinomaKras , Mapk3 , Ptgs2 , Vegfa
pancreatic endocrine carcinomaPgf
pancreatic intraductal papillary-mucinous neoplasmAkt1 , Vegfd
pancreatic mucinous cystadenomaKras
pancreatitisCcl2 , Hsp90ab1 , Map2k1 , Ppp3ca , Ptgs2
papillary carcinomaVegfc
papillary renal cell carcinomaBraf , Hras
papillary thyroid carcinomaBraf , Ctnnb1
papillomaHras , Pla2g4a , Ptgs2
paraplegiaAkt1 , Arf1
ParaproteinemiasBraf , Kras
Parasitic Liver DiseasesKras
parathyroid adenomaHras
parathyroid carcinomaAkt3 , Arf1 , Egln1 , Mapkapk2 , Pla2g4a , Ptgs2 , Sh2d2a
Parkinson's diseaseAkt1 , Casp9 , Mapk1 , Mapk3 , Pla2g6
Parkinson's disease 14Pla2g6
Parkinson's disease 6Cdc42 , Pla2g2a , Pla2g2c , Pla2g2d , Pla2g2f , Pla2g5
ParkinsonismBad , Casp9 , Prkcd , Ptgs2 , Src
patent ductus arteriosusPtpn11
patent foramen ovalePtpn11
Pathologic ConstrictionItgb3
patterned macular dystrophyCtnna1 , Mapkapk3
patterned macular dystrophy 2Ctnna1
patterned macular dystrophy 3Mapkapk3
Penetrating WoundsPgf
Penile NeoplasmsHras , Kras , Pik3ca
Perennial Allergic RhinitisCcl2 , Nos3
Peri-ImplantitisCcl2
periapical periodontitisCcl2
pericardial effusionPtgs2
perinatal necrotizing enterocolitisNos3
Periodontal AtrophyVegfa
Periodontal CystCcl2
periodontitisCcl2
Peripheral Nerve InjuriesCbl , Ccl2 , Ptgs2
peripheral nervous system diseaseCasp9 , Dnm2
peripheral T-cell lymphomaFyn , Rhoa
Peritoneal FibrosisCcl2
Peritoneal NeoplasmsCtnnb1
Periventricular Nodular Heterotopia 8Arf1
peroxisome biogenesis disorder 2BPtpn6
Peroxisome Biogenesis Disorder, Complementation Group 7Prkcz
persistent fetal circulation syndromeNos3
PHACE AssociationBraf
Phelan-McDermid syndromeMapk11 , Mapk12
phencyclidine abuseCalm1 , Calm2
phobic disorderHras
Phyllodes TumorCtnnb1 , Hif1a , Nos3
Pick's diseaseMap2k6
Pierson syndromeRhoa
Pigmented NevusHras , Nras
pilocytic astrocytomaKras
pilomatrixomaCtnnb1
Pituitary NeoplasmsPrkca
Pituitary Stalk Interruption SyndromeRaf1
placental abruptionNos3
Plaque, AtheroscleroticCcl2 , Itgb3
plasma cell neoplasmBraf , Kras
platelet-type bleeding disorder 16Itgb3
Platelet-Type Bleeding Disorder 24Itgb3
pleomorphic xanthoastrocytomaBraf , Cav1 , Grb10 , Hspb1
pleural diseaseCcl2
pleurisyPla2g6 , Ptgs2
Pneumococcal PneumoniaMapk1 , Mapk3
pneumocystosisCcl2
pneumoniaCcl2 , Itgb3 , Nrp1
polyarteritis nodosaVegfa
polycystic kidney diseaseHif1a , Nos3 , Pik3ca , Pla2g4a , Plcg1 , Ptgs2
polycystic liver diseaseCtnnb1
polycystic liver disease 1Ctnnb1
polycystic ovary syndromeAkt2 , Flt4 , Gab1 , Vegfa
polycythemiaEgln1
polymicrogyriaAkt3
Polypoidal Choroidal VasculopathyVegfa
PolyuriaPrkca
portal hypertensionCcl2 , Hsp90aa1 , Mapk1 , Nos3 , Pik3r1 , Prkcd , Ptgs2 , Vegfa
post-traumatic stress disorderCasp9
Postmenopausal OsteoporosisHif1a , Ptk2b
Postoperative Cognitive DysfunctionAkt1 , Mapk1 , Mapk3 , Pik3cb
Posttransfusion PurpuraItgb3
pre-eclampsiaFlt1 , Hif1a , Nos3 , Pgf , Vegfa
pre-malignant neoplasmAkt1 , Casp9 , Hras , Prkaa1 , Ptgs2 , Vegfa
Precocious PubertyPtgs2
Pregnancy in DiabeticsVegfa
Pregnancy-Induced HypertensionNos3
Premature BirthBraf , Pgf , Ptgs2
Premature Obstetric LaborCcl2
Prenatal Exposure Delayed EffectsNos3
Prenatal InjuriesRock1
PresbycusisHspb1
primary biliary cholangitisCdh5 , Hif1a , Mapk14 , Nos3 , Rhoa , Vegfa
primary cerebellar degenerationDnm2
primary cutaneous T-cell non-Hodgkin lymphomaBraf , Plcg1 , Rhoa
primary immunodeficiency diseasePik3cd , Pik3r1
Primary Lymphedema with MyelodysplasiaNck1
primary open angle glaucomaCav1 , Nos3
primary ovarian insufficiencyFyn , Kdr , Nos3
primary pigmented nodular adrenocortical disease 4Prkaca
primary polycythemiaEgln1
primary pulmonary hypertensionCav1 , Nrp2
primary pulmonary hypertension 3Cav1
primary sclerosing cholangitisVegfa
progressive osseous heteroplasiaCtnnb1
progressive supranuclear palsyMap2k6
prolactinomaPtgs2
proliferative diabetic retinopathyCcl2 , Flt1 , Vegfa
prostate adenocarcinomaAkt1 , Akt2 , Akt3 , Braf , Ctnnb1 , Grb2 , Hras , Kdr , Map2k1 , Mapk1 , Pdpk1 , Pik3ca , Pik3cb , Raf1
prostate cancerAkap1 , Akt1 , Akt2 , Akt3 , Cav1 , Ctnna1 , Ctnnb1 , Grb2 , Hif1a , Kdr , Kras , Nos3 , Nras , Pdpk1 , Pik3ca , Pik3cb , Pik3r1 , Pik3r2 , Ptgs2 , Ptk2 , Ptk2b , Rac2 , Raf1 , Src , Vegfa
Prostate Cancer, Hereditary, 1Braf , Hras , Kras , Nras , Vegfa
prostate carcinomaAkt2 , Bad , Prkca
prostate carcinoma in situFlt1 , Kras , Map2k6 , Ptgs2
prostatic hypertrophyBad , Kdr , Ptgs2
Prostatic NeoplasmsAkt1 , Akt2 , Bad , Braf , Camkk2 , Casp9 , Cav1 , Ctnnb1 , Flt1 , Hif1a , Hras , Hsp90ab1 , Itgb3 , Kras , Map2k1 , Map2k2 , Map2k3 , Map2k6 , Mapk3 , Nedd4 , Nos3 , Nrp1 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Ppp3ca , Prkcz , Ptgs2 , Raf1 , Vegfa
prostatitisPtgs2
proteasome-associated autoinflammatory syndrome 1Mapk13 , Mapk14
proteinuriaHif1a , Nck1 , Nck2 , Pak2 , Ptgs2 , Rhoa , Vegfa , Vtn
Proteus syndromeAkt1
pseudoxanthoma elasticumVegfa
psoriasisCav1 , Flt1 , Hif1a , Kdr , Vegfa
PTEN hamartoma tumor syndromePik3ca
pterygiumKdr , Vegfa , Vegfc
ptosisPtpn11
Pulmonary Arterial HypertensionCav1 , Nos3
Pulmonary ContusionCcl2
pulmonary edemaCcl2 , Mapk14 , Nos3 , Vegfa
pulmonary embolismCcl2 , Nos3
pulmonary emphysemaCcl2 , Nos3 , Pgf , Ptgs2
pulmonary eosinophiliaNos3
pulmonary fibrosisBad , Cav1 , Ccl2 , Fyn , Hsp90ab1 , Ptgs2
pulmonary hypertensionCav1 , Ccl2 , Cdh5 , Hif1a , Mapk1 , Mapk3 , Nfatc2 , Nos3 , Pgf , Ptgs2 , Ptk2 , Rhoa , Vegfa , Vegfb
Pulmonary Hypertension, Hypoxia-InducedEgln1 , Egln3 , Nos3
pulmonary tuberculosisAkt1 , Ccl2
pulmonary valve stenosisBraf , Hras
Puromycin Aminonucleoside NephrosisPak2
pyelonephritisPgf
Pyogenic GranulomaNras
Radiation InjuriesHif1a
Radiation PneumonitisNos3 , Vtn
Radioulnar Synostosis with Amegakaryocytic Thrombocytopenia 2Cav1
RASopathyBraf , Cbl , Hras , Kras , Map2k1 , Map2k2 , Nras , Ptpn11 , Raf1
rectal benign neoplasmNras , Pik3ca , Pik3cb
rectum cancerMapk14
RecurrenceCtnnb1 , Flt1 , Hras , Kras , Vegfc
renal cell carcinomaAkt1 , Akt3 , Bad , Cav1 , Ctnna1 , Ctnnb1 , Egln1 , Egln2 , Egln3 , Flt1 , Hif1a , Hspb1 , Kdr , Kras , Map2k1 , Mapk1 , Nrp1 , Pgf , Pik3ca , Pik3r1 , Ptgs2 , Vegfa , Vegfc
Renal Cell Carcinoma 1Ctnnb1
renal fibrosisKras , Mapk1
renal hypertensionNos3
renal Wilms' tumorVegfa
renovascular hypertensionNos3
Reperfusion InjuryAkt1 , Bad , Casp9 , Cav1 , Ccl2 , Cdc42 , Hif1a , Hspb1 , Itgb3 , Kdr , Nos3 , Pik3r1 , Pla2g2a , Pla2g4a , Ppp3ca , Ppp3cb , Prkca , Ptgs2 , Ptk2 , Ptk2b , Src , Vegfc , Vegfd
respiratory allergyNos3 , Ptpn6 , Vegfa
Respiratory Tract GranulomaCcl2
restrictive cardiomyopathyMap2k3 , Map2k6 , Mapk14 , Prkcd
Retina Reperfusion InjuryBad , Ccl2 , Hspb1 , Nos3 , Vegfa
retinal degenerationCcl2 , Nos3
retinal detachmentCasp9 , Ccl2
retinal diseaseMap2k3 , Vegfa
retinal ischemiaHif1a , Vegfa
Retinal NeovascularizationHif1a , Itgav , Vegfa , Vegfb
retinal telangiectasiaKdr , Vegfa
retinal vein occlusionNrp1 , Vegfa , Vegfb
retinitisCcl2
retinitis pigmentosaPrkcg , Vegfa
retinopathy of prematurityFlt1 , Kdr , Nos3 , Vegfa
retrograde amnesiaPtgs2
rhabdomyosarcomaCbl , Hras , Vegfa
rheumatoid arthritisCcl2 , Hif1a , Hsp90aa1 , Hspb1 , Pgf , Pik3r1 , Ptgs2 , Ptk2 , Vegfa
rhinitisCdc42 , Vegfa
Right Ventricular HypertrophyAkt1 , Cdh5 , Nfatc3 , Nfatc4 , Nos3 , Ppp3ca , Ppp3cb , Prkca , Prkcd , Ptk2 , Ptpn11 , Vegfa
Roifman-Chitayat SyndromePik3cd
Romano-Ward SyndromeBraf , Ptpn11
rosette-forming glioneuronal tumorPik3ca
salivary gland carcinomaKdr
Salivary Gland NeoplasmsHras
sarcoidosisPtgs2
sarcomaCcl2 , Hspb1 , Kdr , Pik3ca
SarcopeniaCav1
schizophreniaAkt1 , Cbl , Ccl2 , Ctnna1 , Fyn , Kdr , Mapk3 , Pak2 , Pik3cb , Pik3cd , Ppp3ca , Ppp3cb , Ppp3cc , Ppp3r1 , Ptgs2
sciatic neuropathyCav1 , Ccl2
sclerosing cholangitisHif1a
scoliosisPtpn11
scrapieCasp9
Seasonal Allergic RhinitisKdr , Vegfa
Sebaceous Nevus Syndrome and HemimegalencephalyHras , Kras , Nras
seborrheic keratosisPik3ca
secondary hyperparathyroidismPtgs2
seminomaHras , Kras , Vegfa
Sengers syndromeBraf
Senior-Loken syndromeAkt3
Senior-Loken Syndrome 7Akt3
sensorineural hearing lossPrkcb , Src
SepsisBad , Casp9 , Ccl2 , Flt1 , Fyn , Mapk1 , Mapk3 , Nos3 , Pgf , Pla2g4a , Rac1
Sepsis-Associated EncephalopathyPtgs2
septic myocarditisPrkaa2
Septic PeritonitisPik3r1
severe acute respiratory syndromeCasp9 , Ccl2 , Mapk1 , Mapk3
severe combined immunodeficiencyRac2
severe congenital neutropenia 3Sh2d2a
severe congenital neutropenia 5Sh2d2a
Sezary's diseaseBraf , Mapk1 , Plcg1
ShockMapk1 , Mapk3
short chain acyl-CoA dehydrogenase deficiencyCamkk2 , Pla2g1b , Pxn
short QT syndromeVcl
SHORT syndromePik3r1
short-rib thoracic dysplasia 9 with or without polydactylyPdpk1
Shprintzen-Goldberg CraniosynostosisPrkcz
sickle cell anemiaNos3 , Pgf
silicosisCav1 , Ccl2 , Prkcb
skin benign neoplasmHras
skin diseaseFyn , Ptgs2
skin melanomaBraf , Ccl2 , Ctnnb1 , Hif1a , Hras , Pik3ca
Skin NeoplasmsAkt1 , Ctnnb1 , Flt1 , Hif1a , Hras , Ptgs2 , Ptk2b , Vegfa
skin squamous cell carcinomaFyn
Sleep DeprivationPtgs2
small intestine adenocarcinomaMap2k1 , Map2k2
Small-For-Size SyndromeBad , Vegfa
Smith-Kingsmore SyndromePik3r1 , Pik3r2
Smith-Magenis syndromeMap2k2
spastic ataxiaPik3r5 , Pla2g6
Spastic Ataxia 9, Autosomal RecessiveChp1
Specific Granule DeficiencyNfatc4
spermatocytomaHras
spermatogenic failure 57Map2k1 , Ptpn11
spina bifidaCcl2
Spinal Cord CompressionCcl2 , Nos3
Spinal Cord InjuriesAkt1 , Casp9 , Cav1 , Cdc42 , Flt1 , Hif1a , Hsp90ab1 , Hspb1 , Kdr , Nos3 , Pla2g2a , Pla2g6 , Prkcg , Ptgs2 , Rhoa , Vegfa
Spinal Cord Reperfusion InjuryBad
spinal muscular atrophyHspb1
spinocerebellar ataxia type 14Prkcg
Spinocerebellar AtaxiasPrkcg
Splenic NeoplasmsHras
SplenomegalyKras , Nras
spondylocostal dysostosis 5Mapk3
Spontaneous AbortionsPgf
squamous cell carcinomaAkt1 , Cav1 , Ccl2 , Flt1 , Hras , Hspb1 , Kdr , Kras , Mapk1 , Mapk3 , Pik3ca , Ptgs2 , Ptk2 , Ptpn11 , Vegfa
Staphylococcal PneumoniaAkt1 , Ptpn11
status epilepticusCcl2 , Hspb1 , Pgf , Prkcb , Ptgs2 , Ptk2b , Src , Vegfa
steatotic liver diseaseAkt1 , Ccl2 , Prkaa1 , Prkcd , Ptgs2
Stevens-Johnson syndromeCav1 , Ctnnb1 , Nedd4
Stiff-Person syndromeCtnnb1
STING-associated vasculopathy with onset in infancyCtnna1
stomach cancerCasp9 , Ctnnb1 , Kdr , Kras , Pik3ca , Ptpn11 , Rac1 , Src
stomach carcinomaKras
Stomach NeoplasmsCav1 , Fyn , Hras , Hspb1 , Kras , Mapk1 , Mapk3 , Nos3 , Pik3ca , Prkaa1 , Prkab1 , Prkcb , Ptgs2 , Rhoa
strabismusPtpn11
Streptococcus pneumoniaPik3cd
StrokeAkt1 , Ccl2 , Ctnnb1 , Itgav , Itgb3 , Kdr , Nos3 , Pgf , Pik3ca , Prkaa2 , Prkcd , Ptgs2 , Src , Vegfa
Sturge-Weber syndromeMap2k1
Subarachnoid HemorrhageCasp9 , Hif1a , Nos3 , Pik3cb , Ptgs2
substance-induced psychosisAkt1
Sudden Cardiac DeathItgb3
Sudden DeathVcl
Sudden Hearing LossNos3
sudden infant death syndromeCalm2 , Vegfa
syndromic X-linked intellectual disability Lubs typeVegfd
systemic lupus erythematosusCcl2 , Pgf , Ptgs2
systemic sclerodermaCav1 , Ccl2 , Flt4 , Kdr , Ptgs2 , Vegfa
T-cell acute lymphoblastic leukemiaKras , Ptpn11
T-cell non-Hodgkin lymphomaAkt1 , Hras , Rhoa
Takenouchi-Kosaki SyndromeCdc42
telangiectasisNos3
temporal arteritisCcl2
temporal lobe epilepsyCdc42 , Fyn , Kdr , Pgf , Vegfa
Temporomandibular Joint DisordersHif1a
Temtamy syndromePtpn6
teratomaCtnnb1 , Flt4 , Kdr , Kras
TeratozoospermiaNos3
testicular diseasePpp3ca
Testis Reperfusion InjuryCasp9 , Hif1a , Mapk1 , Mapk3 , Nos3
tethered spinal cord syndromeBraf
tetralogy of FallotFlt4 , Kdr , Nrp1 , Ptpn11
thrombocytopeniaCcl2 , Itgb3 , Ptpn11
Thrombocytopenia 10Ptprj
Thrombocytopenia 6Src
Thrombocytopenic PurpuraItgb3
ThromboembolismNos3
thrombosisPik3cb , Ptgs2 , Vtn
Thrombotic MicroangiopathiesItgb3 , Nos3 , Vegfa
thyroid cancerMapk1
Thyroid Carcinoma, Nonmedullary 1Kras
thyroid gland carcinomaCdh5 , Flt1 , Flt4 , Kdr
thyroid gland diseaseCcl2
Thyroid NeoplasmsAkt2 , Braf , Ccl2 , Ctnnb1 , Hif1a , Hras , Kras , Map2k3 , Mapk1 , Ptgs2
Tibial FracturesPgf
Tongue NeoplasmsHras , Hspb1 , Ptgs2 , Vegfa , Vegfc
tongue squamous cell carcinomaKdr
tooth diseaseRhoa
toxic encephalopathyEgln1 , Prkcd
toxic shock syndromeCcl2 , Pik3cd
transient cerebral ischemiaBad , Casp9 , Cav1 , Cbl , Ccl2 , Flt1 , Hif1a , Hspb1 , Itgb3 , Nos3 , Nrp1
transitional cell carcinomaBraf , Cav1 , Ctnna1 , Ctnnb1 , Hras , Kdr , Kras , Nras , Pla2g4a , Ptgs2
Transplant RejectionBad , Ccl2 , Kdr , Nos3
Trauma and Stressor Related DisordersSrc
traumatic brain injuryBad , Casp9 , Ctnnb1 , Ppp3r1 , Ppp3r2 , Ptgs2
TrichilemmomaHras
tricuspid valve insufficiencyPtpn11
trigeminal neuralgiaMapk1 , Mapk3 , Prkcg
trigonitisRaf1
Triple Negative Breast NeoplasmsCcl2 , Kras
tuberculosisCcl2 , Mapkapk3
tubular aggregate myopathy 1Dnm2
Tufted AngiomaKdr
Tympanic Membrane PerforationVegfa
type 1 diabetes mellitusCasp9 , Cbl , Ccl2 , Nos3
type 2 diabetes mellitusAkt1 , Akt2 , Bad , Braf , Calm1 , Casp9 , Ccl2 , Flt1 , Hif1a , Kdr , Mapk1 , Mapk3 , Nfatc2 , Nos3 , Pik3cb , Pik3r1 , Prkaa1 , Prkaa2 , Prkcb , Prkcz , Ptgs2 , Sphk1 , Src , Vegfa
UlcerHif1a , Itgb3
ulcerative colitisKdr , Ptgs2 , Sphk1 , Vegfa
uremiaFlt1 , Kdr , Nos3 , Ptk2
ureteral obstructionAkt1 , Casp9 , Ccl2 , Mapk1 , Mapk3 , Nos3 , Pak2
urethral obstructionMapk1
urinary bladder cancerAkt1 , Casp9 , Cav1 , Ctnna1 , Ctnnb1 , Hif1a , Hras , Kdr , Kras , Nedd4 , Nos3 , Pik3ca , Ppp3cc , Prkca , Ptgs2 , Rhoa , Src , Vegfa , Vegfc , Vegfd
Urinary Bladder NeoplasmHras , Kras
Urinary IncontinenceMapk1
Urologic NeoplasmsHif1a , Ptgs2 , Rhoa , Vegfa
Uterine Cervical NeoplasmsCtnna1 , Ctnnb1 , Flt1 , Hras , Kdr , Kras , Ptgs2 , Vegfa
Uterine NeoplasmsCtnnb1 , Flt1 , Kras
uveal melanomaKdr , Vegfa
uveitisCcl2
varicoceleCasp9 , Hif1a
Vascular CalcificationCtnnb1
vascular dementiaFlt1 , Mapk1
Vascular MalformationsBraf , Hras , Kras , Map2k1 , Nras , Pik3ca , Pik3r1
Vascular System InjuriesIqgap1
vasculitisCbl , Nos3
Vasculitis of the SkinCcl2
Vaso-occlusive CrisisNos3
velocardiofacial syndromeMapk1
Venous ThrombosisCcl2 , Hif1a , Itgb3 , Kdr , Nos3
Ventilator-Induced Lung InjuryAkt1 , Ptgs2
Ventricular Dysfunction, LeftCtnnb1 , Pik3ca , Prkaa2 , Rac1
Ventricular Dysfunction, RightNos3
Ventricular Fibrillation, Paroxysmal Familial, 1Vcl
Ventricular Premature ComplexesNos3 , Ptpn11
Ventricular RemodelingAkt1 , Ctnnb1 , Hif1a , Vegfa
ventricular septal defectBraf
Ventricular TachycardiaNos3 , Ppp3ca , Ptpn11 , Raf1 , Vcl
vestibular diseaseNos3
vestibular schwannomatosisVegfa
viral pneumoniaCcl2
visceral leishmaniasisPik3cd
vitiligoPik3r1
vulva cancerAkt1 , Nos3
Walker-Warburg syndromeCalm3
Wallerian DegenerationPgf , Pla2g4a , Pla2g6
Weight GainCalm1 , Cav1 , Iqgap1 , Pik3ca
Weissenbacher-Zweymuller syndromeMapk1
Werner syndromeHif1a , Ptpn11
Wernicke encephalopathyPtgs2
Williams-Beuren syndromeSrc
Wilson diseasePpp3ca , Ppp3cb
withdrawal disorderHsp90aa1 , Mapk1 , Mapk3 , Rhoa
Wolff-Parkinson-White syndromeVcl
Wounds and InjuriesVegfa
X-linked agammaglobulinemiaPik3r1
X-linked lymphoproliferative syndrome 1Sh2d2a
Zellweger syndromeVegfa
Pathway Annotations Associated with Genes in the vascular endothelial growth factor signaling pathway
Pathway TermsGene Symbols
abciximab pharmacodynamics pathwayItgb3
acebutolol pharmacodynamics pathwayCalm1 , Prkaca
acetylsalicylic acid pharmacodynamics pathwayPla2g4b , Ptgs2
acute myeloid leukemia pathwayAkt1 , Akt2 , Akt3 , Bad , Braf , Grb2 , Hras , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nras , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Raf1
adenosine monophosphate-activated protein kinase (AMPK) signaling pathwayCalm1 , Calm2 , Calm3 , Camkk2 , Prkaa1 , Prkaa2 , Prkab1 , Prkag1
adenosine signaling pathwayAkt1 , Bad , Braf , Cdc42 , Hras , Map2k2 , Map2k6 , Mapk1 , Mapk11 , Pdpk1 , Pik3ca , Prkcz
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathwayCalm1 , Prkaca
aldosterone signaling pathwayHsp90aa1 , Hsp90ab1 , Kras , Mapk1 , Mapk3 , Pdpk1 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Prkca , Prkcb , Prkcg
alpha-linolenic acid metabolic pathwayPla2g10 , Pla2g12a , Pla2g12b , Pla2g1b , Pla2g2a , Pla2g2c , Pla2g2d , Pla2g2f , Pla2g3 , Pla2g4a , Pla2g4b , Pla2g4e , Pla2g4f , Pla2g5 , Pla2g6
altered extracellular signal-regulated Raf/Mek/Erk signaling pathwayBraf , Kras , Map2k1 , Raf1
altered insulin responsive facilitative sugar transporter mediated glucose transport pathwayAkt2
altered phosphatidylinositol 3-kinase signaling pathwayPik3ca
altered phosphatidylinositol 3-kinase-Akt signaling pathwayAkt1 , Akt2 , Akt3 , Pik3ca
altered Reelin signaling pathwayFyn , Src
altered vascular endothelial growth factor signaling pathwayFlt4
altered vascular endothelial growth factor signaling pathway involving proteins affecting its expressionKdr , Vegfa
altered vascular endothelial growth factor signaling pathway involving the main playersFlt4 , Kdr , Vegfa
altered Wnt signaling, canonical pathwayCtnnb1
Alzheimer's disease pathwayBad , Calm1 , Calm2 , Calm3 , Casp9 , Chp1 , Chp1l1 , Chp2 , Mapk1 , Mapk3 , Ppp3ca , Ppp3cb , Ppp3cc , Ppp3r1 , Ppp3r2 , RGD1565588
amiodarone pharmacodynamics pathwayCalm1 , Prkaca
amlodipine pharmacodynamics pathwayCalm1 , Prkaca
amyotrophic lateral sclerosis pathwayBad , Casp9 , Chp1 , Chp1l1 , Chp2 , Map2k3 , Map2k6 , Mapk11 , Mapk12 , Mapk13 , Mapk14 , Ppp3ca , Ppp3cb , Ppp3cc , Ppp3r1 , Ppp3r2 , Rac1 , RGD1565588
androgen signaling pathwayHsp90aa1 , Hsp90ab1
angiotensin II signaling pathwayCcl2 , Pdpk1 , Pla2g6 , Prkcz
angiotensin II signaling pathway via AT2 receptorPtpn6
antigen processing and presentation pathwayHsp90aa1 , Hsp90ab1
antipyrine drug pathwayPla2g4b , Ptgs2
apoptotic cell death pathwayAkt1 , Akt2 , Akt3 , Bad , Casp9 , Chp1 , Chp1l1 , Chp2 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Ppp3ca , Ppp3cb , Ppp3cc , Ppp3r1 , Ppp3r2 , Prkaca , RGD1565588
arachidonic acid metabolic pathwayPla2g10 , Pla2g12a , Pla2g12b , Pla2g1b , Pla2g2a , Pla2g2c , Pla2g2d , Pla2g2f , Pla2g3 , Pla2g4a , Pla2g4b , Pla2g4e , Pla2g4f , Pla2g5 , Pla2g6 , Ptgs2
Arf family mediated signaling pathwayArf1 , Rac1
arginine and proline metabolic pathwayNos3
arrhythmogenic right ventricular cardiomyopathy pathwayCtnna1 , Ctnnb1 , Itgb3
atenolol pharmacodynamics pathwayCalm1 , Prkaca
autophagy pathwayHgs , Prkaa1 , Prkaa2
axitinib pharmacodynamics pathwayFlt1 , Flt4 , Kdr
azathioprine pharmacodynamics pathwayRac1
B cell receptor signaling pathwayAkt1 , Akt2 , Akt3 , Chp1 , Chp1l1 , Chp2 , Grb2 , Hras , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nfat5 , Nfatc2 , Nfatc3 , Nfatc4 , Nras , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Plcg2 , Ppp3ca , Ppp3cb , Ppp3cc , Ppp3r1 , Ppp3r2 , Prkcb , Ptpn6 , Rac1 , Rac2 , Raf1 , RGD1560225 , RGD1565588
basal cell carcinoma pathwayCtnnb1
betaxolol pharmacodynamics pathwayCalm1 , Prkaca
bevacizumab pharmacodynamics pathwayFlt1 , Kdr , Vegfa
bile acid transport pathwayPrkaca
bisoprolol pharmacodynamics pathwayCalm1 , Prkaca
Bone morphogenetic proteins signaling pathwayMapk1
brain-derived neurotrophic factor signaling pathwayGrb2
bupranolol drug pathwayCalm1 , Prkaca
bupranolol pharmacodynamics pathwayCalm1 , Prkaca
c-Jun N-terminal kinases MAPK signaling pathwayCdc42 , Rac1
calcineurin signaling pathwayNfatc2 , Nfatc3 , Nfatc4 , Ppp3ca , Ppp3cb , Ppp3cc , Ppp3r1 , Ppp3r2
calcium signaling pathway via the calcium-sensing receptorRhoa
calcium/calcium-mediated signaling pathwayCalm1 , Calm2 , Calm3 , Chp1 , Chp1l1 , Chp2 , Nos3 , Plcg1 , Plcg2 , Ppp3ca , Ppp3cb , Ppp3cc , Ppp3r1 , Ppp3r2 , Prkaca , Prkca , Prkcb , Prkcg , Ptk2b , RGD1565588 , Sphk1 , Sphk2
calcium/calmodulin dependent kinase 2 signaling pathwayCalm1 , Calm2 , Calm3
cardiomyopathy pathwayMap2k6
carvedilol pharmacodynamics pathwayCalm1 , Prkaca
celecoxib pharmacodynamics pathwayPla2g4b , Ptgs2
celecoxib pharmacokinetics pathwayPtgs2
cell-extracellular matrix signaling pathwayItgb3 , Vtn
ceramide signaling pathwayAkt1 , Akt2 , Akt3 , Bad , Braf , Casp9 , Cdc42 , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Pgf , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Prkcd , Prkcz , Rac1 , Rac2 , Raf1 , Sphk2 , Vegfa , Vegfb , Vegfc , Vegfd
Chagas disease pathwayAkt1 , Akt2 , Akt3 , Mapk1 , Mapk11 , Mapk12 , Mapk13 , Mapk14 , Mapk3 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5
chaperone mediated autophagy pathwayHsp90aa1
chemokine mediated signaling pathwayAkt1 , Akt2 , Akt3 , Braf , Ccl2 , Cdc42 , Grb2 , Hras , Kras , Map2k1 , Mapk1 , Mapk3 , Nras , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Prkaca , Prkcb , Prkcd , Prkcz , Ptk2 , Ptk2b , Pxn , Rac1 , Rac2 , Raf1 , Rhoa , Rock1 , Shc2
chronic myeloid leukemia pathwayAkt1 , Akt2 , Akt3 , Bad , Braf , Cbl , Grb2 , Hras , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nras , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Ptpn11 , Raf1 , Shc2
colorectal cancer pathwayAkt1 , Akt2 , Akt3 , Bad , Braf , Casp9 , Ctnnb1 , Kras , Map2k1 , Mapk1 , Mapk3 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Rac1 , Rac2 , Raf1 , Rhoa
cortisol signaling pathwayHsp90aa1 , Hsp90ab1
cyclooxygenase mediated pathway of arachidonic acid metabolismPla2g4a , Ptgs2
cytokine mediated signaling pathwayFlt1 , Flt4 , Kdr , Vegfc , Vegfd
diclofenac pharmacodynamics pathwayPla2g4b , Ptgs2
diflunisal pharmacodynamics pathwayPla2g4b , Ptgs2
dilated cardiomyopathy pathwayItgb3 , Prkaca
diltiazem pharmacodynamics pathwayCalm1 , Prkaca
disopyramide pharmacodynamics pathwayCalm1 , Prkaca
dobutamine pharmacodynamics pathwayCalm1 , Prkaca
dopamine signaling pathwayPpp3ca , Ppp3cb , Ppp3cc , Prkaca , Src
doxorubicin pharmacokinetics pathwayNos3
E-cadherin signaling pathwayAkt1 , Akt2 , Cdc42 , Ctnna1 , Ctnnb1 , Fyn , Iqgap1 , Nck1 , Pik3ca , Pik3r1 , Plcg1 , Rac1 , Rhoa , Rock1 , Src , Vcl
eicosanoid signaling pathwayAkt1 , Fyn , Mapk11 , Mapk14 , Nos3 , Pik3r5 , Prkaca , Prkca , Prkcd , Prkcg , Prkcz , Rac1 , Rhoa , Rock1 , Src
eicosanoid signaling pathway via peroxisome proliferator-activated receptor gammaPdpk1
endocytosis pathwayCav1 , Cbl , Cdc42 , Dnm2 , Flt1 , Hgs , Hras , Kdr , Nedd4 , Prkcz , Rhoa , Src
endometrial cancer pathwayAkt1 , Akt2 , Akt3 , Bad , Braf , Casp9 , Ctnna1 , Ctnnb1 , Grb2 , Hras , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nras , Pdpk1 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Raf1
Endoplasmic Reticulum-associated degradation pathwayHsp90aa1 , Hsp90ab1
endothelin signaling pathwayAkt1 , Cdc42 , Hras , Map2k1 , Map2k2 , Mapk1 , Mapk14 , Mapk3 , Nfatc3 , Pla2g4a , Prkca , Prkcd , Prkcg , Ptk2b , Rac1 , Raf1 , Rhoa , Src
Entamoebiasis pathwayHspb1 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Prkaca , Prkca , Prkcb , Prkcg , Ptk2 , Vcl
ephrin - ephrin receptor bidirectional signaling axisCbl , Cdc42 , Fyn , Grb2 , Hras , Itgb3 , Map2k1 , Mapk1 , Mapk3 , Nck1 , Nck2 , Nras , Pik3ca , Pik3r1 , Pik3r5 , Plcg1 , Pxn , Rac1 , Rhoa , Rock1 , Src
epidermal growth factor/neuregulin signaling pathwayAkt1 , Akt2 , Akt3 , Bad , Braf , Cbl , Gab1 , Grb2 , Hras , Hsp90aa1 , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nck1 , Nck2 , Nras , Pak2 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Plcg1 , Plcg2 , Prkca , Prkcb , Prkcg , Prkcz , Ptk2 , Ptpn11 , Ptpn6 , Ptprj , Raf1 , Shc2 , Src
eptifibatide pharmacodynamics pathwayItgb3
Erk5 MAPK signaling pathwaySh2d2a
erythropoietin signaling pathwayCbl , Gab1 , Grb2 , Hras , Mapk14 , Pik3r1 , Plcg1 , Plcg2 , Ptpn11 , Ptpn6
esmolol pharmacodynamics pathwayCalm1 , Prkaca
estrogen signaling pathwayHsp90aa1 , Hsp90ab1 , Src
ether lipid metabolic pathwayPla2g10 , Pla2g12a , Pla2g12b , Pla2g1b , Pla2g2a , Pla2g2c , Pla2g2d , Pla2g2f , Pla2g3 , Pla2g4a , Pla2g4b , Pla2g4e , Pla2g4f , Pla2g5 , Pla2g6
ether lipid metabolic pathwayPla2g10 , Pla2g12a , Pla2g12b , Pla2g1b , Pla2g2a , Pla2g2c , Pla2g2d , Pla2g2f , Pla2g3 , Pla2g4a , Pla2g4b , Pla2g4e , Pla2g4f , Pla2g5 , Pla2g6
etodolac pharmacodynamics pathwayPla2g4b , Ptgs2
etoposide pharmacodynamics pathwayPtgs2
etoposide pharmacokinetics pathwayPtgs2
Fabry disease pathwaySphk2
FasL mediated signaling pathwayAkt1 , Map2k6 , Mapk11 , Mapk14 , Pdpk1 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Src
Fc epsilon receptor mediated signaling pathwayAkt1 , Akt2 , Akt3 , Fyn , Grb2 , Hras , Kras , Map2k1 , Map2k2 , Map2k3 , Map2k6 , Mapk1 , Mapk11 , Mapk12 , Mapk13 , Mapk14 , Mapk3 , Nras , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Pla2g10 , Pla2g12a , Pla2g12b , Pla2g1b , Pla2g2a , Pla2g2c , Pla2g2d , Pla2g2f , Pla2g3 , Pla2g4a , Pla2g4b , Pla2g4e , Pla2g4f , Pla2g5 , Pla2g6 , Plcg1 , Plcg2 , Prkca , Prkcd , Prkcg , Rac1 , Rac2 , Raf1
Fc gamma receptor mediated signaling pathwayAkt1 , Akt2 , Akt3 , Cdc42 , Dnm2 , Map2k1 , Mapk1 , Mapk3 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Pla2g4a , Pla2g6 , Plcg1 , Plcg2 , Prkca , Prkcb , Prkcd , Prkcg , Rac1 , Rac2 , Raf1 , Sphk1 , Sphk2
fenoprofen pharmacodynamics pathwayPla2g4b , Ptgs2
fibroblast growth factor signaling pathwayAkt1 , Cbl , Gab1 , Grb2 , Mapk1 , Mapk3 , Pdpk1 , Pik3ca , Pik3r1 , Plcg1 , Ptk2b , Ptpn11 , Src
flecainde pharmacodynamics pathwayCalm1 , Prkaca
flurbiprofen pharmacodynamics pathwayPla2g4b , Ptgs2
forkhead class A signaling pathwayAkt1 , Vtn
fosphenytoin pharmacodynamics pathwayCalm1 , Prkaca
Gaucher's disease pathwaySphk2
glioma pathwayAkt1 , Akt2 , Akt3 , Braf , Calm1 , Calm2 , Calm3 , Grb2 , Hras , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nras , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Plcg1 , Plcg2 , Prkca , Prkcb , Prkcg , Raf1 , Shc2
glutamate signaling pathwayChp1 , Chp1l1 , Chp2 , Mapk1 , Mapk3 , Pla2g10 , Pla2g12a , Pla2g12b , Pla2g1b , Pla2g2a , Pla2g2c , Pla2g2d , Pla2g2f , Pla2g3 , Pla2g4a , Pla2g4b , Pla2g4e , Pla2g4f , Pla2g5 , Pla2g6 , Ppp3ca , Ppp3cb , Ppp3cc , Ppp3r1 , Ppp3r2 , Prkaca , Prkca , Prkcb , Prkcg , RGD1565588
glycerophospholipid metabolic pathwayPla2g10 , Pla2g12a , Pla2g12b , Pla2g1b , Pla2g2a , Pla2g2c , Pla2g2d , Pla2g2f , Pla2g3 , Pla2g4a , Pla2g4b , Pla2g4e , Pla2g4f , Pla2g5 , Pla2g6
glycogen degradation pathwayCalm1 , Calm2 , Calm3
glypican signaling pathwayFlt1 , Fyn , Pla2g2a , Src , Vegfa
gonadotropin-releasing hormone signaling pathwayCalm1 , Calm2 , Calm3 , Cdc42 , Grb2 , Hras , Kras , Map2k1 , Map2k2 , Map2k3 , Map2k6 , Mapk1 , Mapk11 , Mapk12 , Mapk13 , Mapk14 , Mapk3 , Nras , Pla2g10 , Pla2g12a , Pla2g12b , Pla2g1b , Pla2g2a , Pla2g2c , Pla2g2d , Pla2g2f , Pla2g3 , Pla2g4a , Pla2g4b , Pla2g4e , Pla2g4f , Pla2g5 , Pla2g6 , Prkaca , Prkca , Prkcb , Prkcd , Ptk2b , Raf1 , Src
granulocyte-macrophage colony-stimulating factor signaling pathwayCcl2 , Grb2 , Hras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nras , Pik3ca , Pik3r1 , Prkaca , Ptpn11 , Raf1
Hedgehog signaling pathwayAkt1 , Fbxw11 , Map2k1 , Pik3ca , Pik3r1 , Prkaca , Prkcd
hepatitis C pathwayAkt1 , Akt2 , Akt3 , Bad , Braf , Grb2 , Hras , Kras , Mapk1 , Mapk11 , Mapk12 , Mapk13 , Mapk14 , Mapk3 , Nras , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Raf1
Huntington's disease pathwayCasp9
hypertrophic cardiomyopathy pathwayItgb3 , Prkaa1 , Prkaa2 , Prkab1 , Prkag1
hypoxia inducible factor pathwayAkt1 , Egln1 , Egln2 , Egln3 , Flt1 , Hif1a , Kdr , Vegfa
ibuprofen pharmacodynamics pathwayPla2g4b , Ptgs2
ibuprofen pharmacokinetics pathwayPtgs2
ibutilide pharmacodynamics pathwayCalm1 , Prkaca
indometacin pharmacodynamics pathwayPla2g2a , Pla2g4b , Ptgs2
indometacin pharmacodynamics pathwayPla2g2a , Pla2g4b , Ptgs2
influenza A pathwayAkt1 , Akt2 , Akt3 , Casp9 , Map2k1 , Map2k2 , Map2k3 , Map2k6 , Mapk1 , Mapk11 , Mapk12 , Mapk13 , Mapk14 , Mapk3 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Prkca , Prkcb , Raf1
inositol metabolic pathwayPik3ca
inositol phosphate metabolic pathwayPik3ca , Pik3cb , Pik3cd , Plcg1 , Plcg2
insulin responsive facilitative sugar transporter mediated glucose transport pathwayAkt1 , Akt2 , Calm1 , Calm2 , Calm3 , Cbl , Iqgap1 , Prkcz , Rac1
insulin secretion pathwayCdc42
insulin signaling pathwayAkt1 , Akt2 , Akt3 , Bad , Braf , Calm1 , Calm2 , Calm3 , Cav1 , Cbl , Grb10 , Grb2 , Hras , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nck1 , Nck2 , Nras , Pdpk1 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Prkaa1 , Prkaa2 , Prkab1 , Prkaca , Prkag1 , Prkca , Prkcb , Prkcg , Prkcz , Ptpn11 , Raf1 , Shc2
insulin-like growth factor signaling pathwayAkt1 , Bad , Grb10 , Grb2 , Hras , Nck2 , Pdpk1 , Pik3ca , Pik3r1 , Prkcd , Prkcz , Ptpn11 , Pxn , Raf1
integrin mediated signaling pathwayItgav , Itgb3 , Nck2 , Ptk2 , Pxn
interleukin-1 signaling pathwayMap2k6 , Pik3ca , Pik3r1 , Prkcz
interleukin-12 signaling pathwayMap2k3 , Map2k6 , Mapk14 , Ppp3ca , Ppp3cb , Ppp3r1 , Sphk2
interleukin-2 signaling pathwayFyn , Grb2 , Hras , Map2k1 , Map2k2 , Mapk1 , Mapk11 , Mapk14 , Mapk3 , Mapkapk2 , Nras , Pik3ca , Pik3r1 , Prkcb , Ptk2b , Ptpn11 , Raf1 , Rhoa
interleukin-23 signaling pathwayCcl2 , Pik3ca , Pik3r1
interleukin-3 signaling pathwayGrb2 , Pik3ca , Pik3r1 , Prkaca , Ptpn11
interleukin-4 signaling pathwayAkt1 , Cbl , Fes , Grb2 , Itgb3 , Mapk14 , Pik3ca , Pik3r1 , Ptpn6
interleukin-5 signaling pathwayGrb2 , Pik3ca , Pik3r1 , Ptpn11
interleukin-6 signaling pathwayAkt1 , Gab1 , Grb2 , Map2k6 , Mapk11 , Mapk14 , Pik3ca , Pik3r1 , Prkcd , Ptpn11 , Rac1
intrinsic apoptotic pathwayBad , Casp9
isoprenaline pharmacodynamics pathwayCalm1 , Prkaca
isradipine pharmacodynamics pathwayCalm1 , Prkaca
Jak-Stat signaling pathwayAkt1 , Akt2 , Akt3 , Cbl , Grb2 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Ptk2b , Ptpn11 , Ptpn6
ketoprofen pharmacodynamics pathwayPla2g4b , Ptgs2
ketorolac pharmacodynamics pathwayPla2g4b , Ptgs2
Krabbe disease pathwaySphk2
Leishmaniasis pathwayMapk1 , Mapk11 , Mapk12 , Mapk13 , Mapk14 , Mapk3 , Prkcb , Ptgs2 , Ptpn6
leptin system pathwayPtpn11
leukotriene C4 synthase deficiency pathwayPla2g4b , Ptgs2
levobunolol pharmacodynamics pathwayCalm1 , Prkaca
lidocaine pharmacodynamics pathwayCalm1 , Prkaca
linoleic acid metabolic pathwayPla2g10 , Pla2g12a , Pla2g12b , Pla2g1b , Pla2g2a , Pla2g2c , Pla2g2d , Pla2g2f , Pla2g3 , Pla2g4a , Pla2g4b , Pla2g4e , Pla2g4f , Pla2g5 , Pla2g6
long term depressionBraf , Hras , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nras , Pla2g10 , Pla2g12a , Pla2g12b , Pla2g1b , Pla2g2a , Pla2g2c , Pla2g2d , Pla2g2f , Pla2g3 , Pla2g4a , Pla2g4b , Pla2g4e , Pla2g4f , Pla2g5 , Pla2g6 , Prkca , Prkcb , Prkcg , Raf1
long term potentiationBraf , Calm1 , Calm2 , Calm3 , Chp1 , Chp1l1 , Chp2 , Hras , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nras , Ppp3ca , Ppp3cb , Ppp3cc , Ppp3r1 , Ppp3r2 , Prkaca , Prkca , Prkcb , Prkcg , Ptk2 , Raf1 , RGD1565588
lornoxicam pharmacodynamics pathwayPla2g4b , Ptgs2
magnesium salicylate pharmacodynamics pathwayPla2g4b , Ptgs2
measles pathwayAkt1 , Akt2 , Akt3 , Fyn , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5
mefenamic acid pharmacodynamics pathwayPla2g4b , Ptgs2
melanoma pathwayAkt1 , Akt2 , Akt3 , Bad , Braf , Hras , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nras , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Raf1
meloxicam pharmacodynamics pathwayPla2g4b , Ptgs2
mercaptopurine pharmacodynamics pathwayRac1
mercaptopurine pharmacokinetics pathwayRac1
metachromatic leukodystrophy pathwaySphk2
metoprolol pharmacodynamics pathwayCalm1 , Prkaca
mexiletine pharmacodynamics pathwayCalm1 , Prkaca
mitochondrial autophagy pathwaySrc
mitogen activated protein kinase signaling pathwayAkt1 , Akt2 , Akt3 , Braf , Cdc42 , Chp1 , Chp1l1 , Chp2 , Grb2 , Hras , Hspb1 , Kras , Map2k1 , Map2k2 , Map2k3 , Map2k6 , Mapk1 , Mapk11 , Mapk12 , Mapk13 , Mapk14 , Mapk3 , Mapkapk2 , Mapkapk3 , Nfatc2 , Nfatc4 , Nras , Pak2 , Pla2g10 , Pla2g12a , Pla2g12b , Pla2g1b , Pla2g2a , Pla2g2c , Pla2g2d , Pla2g2f , Pla2g3 , Pla2g4a , Pla2g4b , Pla2g4e , Pla2g4f , Pla2g5 , Pla2g6 , Ppp3ca , Ppp3cb , Ppp3cc , Ppp3r1 , Ppp3r2 , Prkaca , Prkca , Prkcb , Prkcg , Rac1 , Rac2 , Raf1 , RGD1565588
mTOR signaling pathwayAkt1 , Akt2 , Akt3 , Braf , Fbxw11 , Hif1a , Hras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nras , Pdpk1 , Pgf , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Prkaa1 , Prkaa2 , Prkca , Pxn , Rac1 , Raf1 , Rhoa , Vegfa , Vegfb , Vegfc , Vegfd
myocarditis pathwayCasp9 , Cav1 , Fyn , Rac1 , Rac2
N-cadherin signaling pathwayCalm1 , Calm2 , Calm3 , Cdc42 , Ctnna1 , Ctnnb1 , Pik3ca , Pik3r1 , Plcg1 , Ptpn11 , Rac1 , Rhoa , Rock1
nabumetone pharmacodynamics pathwayPla2g4b , Ptgs2
nadolol pharmacodynamics pathwayCalm1 , Prkaca
naproxen pharmacodynamics pathwayPla2g4b , Ptgs2
nebivolol pharmacodynamics pathwayCalm1 , Prkaca
nerve growth factor signaling pathwaySrc
neurotrophic factor signaling pathwayAkt1 , Akt2 , Akt3 , Bad , Braf , Calm1 , Calm2 , Calm3 , Cdc42 , Gab1 , Grb2 , Hras , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk11 , Mapk12 , Mapk13 , Mapk14 , Mapk3 , Mapkapk2 , Nras , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Plcg1 , Plcg2 , Prkcd , Ptpn11 , Rac1 , Raf1 , Rhoa , Shc2
nifedipine pharmacodynamics pathwayCalm1 , Prkaca
nimodipine pharmacodynamics pathwayCalm1 , Prkaca
nisoldipine pharmacodynamics pathwayCalm1 , Prkaca
nitrendipine pharmacodynamics pathwayCalm1 , Prkaca
NOD-like receptor signaling pathwayHsp90aa1 , Hsp90ab1 , Mapk1 , Mapk11 , Mapk12 , Mapk13 , Mapk14 , Mapk3
non-small cell lung carcinoma pathwayAkt1 , Akt2 , Akt3 , Bad , Braf , Casp9 , Grb2 , Hras , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nras , Pdpk1 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Plcg1 , Plcg2 , Prkca , Prkcb , Prkcg , Raf1
Notch signaling pathwayCbl
nuclear factor kappa B signaling pathwayMapk14 , Pik3ca , Pik3r1 , Prkca , Src
nuclear factor of activated T-cells signaling pathwayNfatc2 , Nfatc3 , Nfatc4
p38 MAPK signaling pathwayCalm1 , Calm2 , Calm3 , Cdc42 , Map2k3 , Map2k6 , Mapk11 , Mapk12 , Mapk13 , Mapk14 , Mapkapk2 , Mapkapk3 , Rac1
p53 signaling pathwayAkt1 , Casp9 , Mapk14 , Prkcd
pancreatic cancer pathwayAkt1 , Akt2 , Akt3 , Bad , Braf , Casp9 , Cdc42 , Kras , Map2k1 , Mapk1 , Mapk3 , Pgf , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Rac1 , Rac2 , Raf1 , Vegfa , Vegfb , Vegfc , Vegfd
paracetamol drug pathwayPla2g4b , Ptgs2
Parkinson's disease pathwayCasp9
penbutolol pharmacodynamics pathwayCalm1 , Prkaca
phagocytosis pathwayHgs , Itgb3 , Rac1
phenytoin pharmacodynamics pathwayCalm1 , Prkaca
phosphatidylinositol 3-kinase class I signaling pathwayArf1 , Fyn , Hras , Hsp90aa1 , Nras , Pdpk1 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Plcg1 , Plcg2 , Rac1 , Rhoa , Src
phosphatidylinositol 3-kinase signaling pathwayCalm1 , Calm2 , Calm3 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Plcg1 , Plcg2 , Prkca , Prkcb , Prkcg
phosphatidylinositol 3-kinase-Akt signaling pathwayAkt1 , Akt2 , Akt3 , Bad , Casp9 , Hif1a , Hsp90aa1 , Pdpk1 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Prkaca , Raf1 , Src , Vegfa
phosphoinositide metabolic pathwayPik3ca , Pik3cd , Pik3r1
pindolol pharmacodynamics pathwayCalm1 , Prkaca
piroxicam pharmacodynamics pathwayPla2g4b , Ptgs2
platelet aggregation pathwayItgb3
platelet-derived growth factor signaling pathwayBraf , Cav1 , Cbl , Dnm2 , Fyn , Gab1 , Grb10 , Grb2 , Hras , Iqgap1 , Itgav , Itgb3 , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nck1 , Nck2 , Nras , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Pla2g4a , Plcg1 , Prkca , Prkcd , Ptpn11 , Ptprj , Rac1 , Raf1 , Rhoa , Shb , Sphk1 , Src
prednisolone pharmacodynamics pathwayHsp90aa1
prednisolone pharmacokinetics pathwayHsp90aa1
prion disease pathwayFyn , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Prkaca
pro-inflammatory cytokine mediated pathwayPtgs2
procainamide pharmacodynamics pathwayCalm1 , Prkaca
propranolol pharmacodynamics pathwayCalm1 , Prkaca
prostanoid biosynthetic pathwayPtgs2
prostate cancer pathwayAkt1 , Akt2 , Akt3 , Bad , Braf , Casp9 , Ctnnb1 , Grb2 , Hras , Hsp90aa1 , Hsp90ab1 , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nras , Pdpk1 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Raf1
protein kinase A (PKA) signaling pathwayAkap1 , Prkaca
protein kinase C (PKC) signaling pathwayFyn , Hsp90aa1 , Pdpk1 , Prkca , Prkcb , Prkcd , Prkcg , Prkcz
quinidine pharmacodynamics pathwayCalm1 , Prkaca
Reelin signaling pathwayAkt1 , Cbl , Fyn , Nck2 , Pik3ca , Pik3r1 , Src
renal cell carcinoma pathwayAkt1 , Akt2 , Akt3 , Braf , Cdc42 , Egln1 , Egln2 , Egln3 , Gab1 , Grb2 , Hif1a , Hras , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nras , Pak2 , Pgf , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Ptpn11 , Rac1 , Raf1 , Vegfa , Vegfb , Vegfc , Vegfd
Retinoic acid-inducible gene (RIG) I-like receptor signaling pathwayMapk11 , Mapk12 , Mapk13 , Mapk14
reverse cholesterol transport pathwayCav1
rheumatoid arthritis pathwayFlt1 , Pgf , Vegfa , Vegfb
Rho/Rac/Cdc42 mediated signaling pathwayCbl , Cdc42 , Iqgap1 , Ptk2b , Rac1 , Rhoa
ribosome biogenesis pathwayPrkcb
salicylic acid pharmacodynamics pathwayPla2g4b , Ptgs2
scatter factor/hepatocyte growth factor signaling pathwayCbl , Gab1 , Grb2 , Pik3r1 , Plcg1 , Ptpn11 , Src
schizophrenia pathwayPpp3cc
signaling pathway pertinent to the brain and nervous systemSrc
sleeping sickness pathwayPrkca , Prkcb , Prkcg
small cell lung carcinoma pathwayAkt1 , Akt2 , Akt3 , Casp9 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Ptgs2 , Ptk2
sodium salicylate pharmacodynamics pathwayPla2g4b , Ptgs2
somatostatin signaling pathwayPtpn11 , Ptprj , Src
sotalol pharmacodynamics pathwayCalm1 , Prkaca
sphingolipid metabolic pathwaySphk1 , Sphk2
sphingosine 1-phosphate signaling pathwayAkt1 , Akt3 , Cdc42 , Cdh5 , Flt1 , Itgav , Itgb3 , Kdr , Mapk1 , Mapk14 , Mapk3 , Plcg1 , Ptgs2 , Rac1 , Rhoa , Sphk1 , Sphk2 , Src , Vegfa
sulindac pharmacodynamics pathwayPla2g4b , Ptgs2
syndecan signaling pathwayDnm2 , Fyn , Hras , Mapk1 , Mapk3 , Prkaca , Prkca , Prkcd , Rac1 , Rhoa , Src
T cell receptor signaling pathwayAkt1 , Akt2 , Akt3 , Cbl , Cdc42 , Chp1 , Chp1l1 , Chp2 , Fyn , Grb2 , Hras , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk11 , Mapk12 , Mapk13 , Mapk14 , Mapk3 , Nck1 , Nck2 , Nfat5 , Nfatc2 , Nfatc3 , Nfatc4 , Nras , Pak2 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Plcg1 , Ppp3ca , Ppp3cb , Ppp3cc , Ppp3r1 , Ppp3r2 , Ptpn6 , Raf1 , RGD1560225 , RGD1565588 , Rhoa
tenoxicam pharmacodynamics pathwayPla2g4b , Ptgs2
the extracellular signal-regulated Raf/Mek/Erk signaling pathwayBraf , Hras , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nras , Prkcd , Ptk2b , Raf1
thyroid cancer pathwayBraf , Ctnnb1 , Hras , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nras
tiaprofenic acid pharmacodynamics pathwayPla2g4b , Ptgs2
timolol pharmacodynamics pathwayCalm1 , Prkaca
tioguanine pharmacodynamics pathwayRac1
tirofiban pharmacodynamics pathwayItgb3
Toll-like receptor signaling pathwayAkt1 , Akt2 , Akt3 , Map2k1 , Map2k2 , Map2k3 , Map2k6 , Mapk1 , Mapk11 , Mapk12 , Mapk13 , Mapk14 , Mapk3 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Rac1
tolmetin pharmacodynamics pathwayPla2g4b , Ptgs2
toxoplasmosis pathwayAkt1 , Akt2 , Akt3 , Bad , Casp9 , Map2k3 , Map2k6 , Mapk1 , Mapk11 , Mapk12 , Mapk13 , Mapk14 , Mapk3 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Pla2g10 , Pla2g12a , Pla2g12b , Pla2g1b , Pla2g2a , Pla2g2c , Pla2g2d , Pla2g2f , Pla2g3 , Pla2g4a , Pla2g4b , Pla2g4e , Pla2g4f , Pla2g5 , Pla2g6
Trail mediated signaling pathwayMapk1 , Mapk3 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3
transforming growth factor-beta signaling pathwayCav1
transforming growth factor-beta Smad dependent signaling pathwayCav1 , Ctnnb1 , Grb2 , Pdpk1 , Rhoa
transforming growth factor-beta superfamily mediated signaling pathwayMapk1 , Mapk3 , Rhoa , Rock1
tuberculosis pathwayAkt1 , Akt2 , Akt3 , Bad , Calm1 , Calm2 , Calm3 , Casp9 , Chp1 , Chp1l1 , Chp2 , Mapk1 , Mapk11 , Mapk12 , Mapk13 , Mapk14 , Mapk3 , Ppp3ca , Ppp3cb , Ppp3cc , Ppp3r1 , Ppp3r2 , Raf1 , RGD1565588 , Rhoa , Sphk1 , Sphk2 , Src
tumor necrosis factor mediated signaling pathwayCav1 , Map2k3 , Prkcz
type 2 diabetes mellitus pathwayAkt2 , Mapk1 , Mapk3 , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Prkcd , Prkcz
type II interferon signaling pathwayAkt1 , Calm1 , Calm2 , Calm3 , Cbl , Map2k1 , Mapk1 , Mapk3 , Pik3ca , Pik3r1 , Prkcd , Ptpn11
ubiquitin/proteasome degradation pathwayCbl , Fbxw11 , Nedd4 , Src
urinary bladder cancer pathwayBraf , Hras , Kras , Map2k1 , Map2k2 , Mapk1 , Mapk3 , Nras , Pgf , Raf1 , Vegfa , Vegfb , Vegfc , Vegfd
valdecoxib pharmacodynamics pathwayPla2g4b , Ptgs2
vascular endothelial growth factor signaling pathwayAkap1 , Akt1 , Akt2 , Akt3 , Arf1 , Bad , Braf , Calm1 , Calm2 , Calm3 , Camkk2 , Casp9 , Cav1 , Cbl , Ccl2 , Cdc42 , Cdh5 , Chp1 , Chp1l1 , Chp2 , Ctnna1 , Ctnnb1 , Dnm2 , Egln1 , Egln2 , Egln3 , Fbxw11 , Fes , Flt1 , Flt4 , Fyn , Gab1 , Grb10 , Grb2 , Hgs , Hif1a , Hras , Hsp90aa1 , Hsp90ab1 , Hspb1 , Iqgap1 , Itgav , Itgb3 , Kdr , Kras , Map2k1 , Map2k2 , Map2k3 , Map2k6 , Mapk1 , Mapk11 , Mapk12 , Mapk13 , Mapk14 , Mapk3 , Mapkapk2 , Mapkapk3 , Myof , Nck1 , Nck2 , Nedd4 , Nfat5 , Nfatc2 , Nfatc3 , Nfatc4 , Nos3 , Nras , Nrp1 , Nrp2 , Pak2 , Pdpk1 , Pgf , Pik3ca , Pik3cb , Pik3cd , Pik3r1 , Pik3r2 , Pik3r3 , Pik3r5 , Pla2g10 , Pla2g12a , Pla2g12b , Pla2g1b , Pla2g2a , Pla2g2c , Pla2g2d , Pla2g2f , Pla2g3 , Pla2g4a , Pla2g4b , Pla2g4e , Pla2g4f , Pla2g5 , Pla2g6 , Plcg1 , Plcg2 , Ppp3ca , Ppp3cb , Ppp3cc , Ppp3r1 , Ppp3r2 , Prkaa1 , Prkaa2 , Prkab1 , Prkaca , Prkag1 , Prkca , Prkcb , Prkcd , Prkcg , Prkcz , Ptgs2 , Ptk2 , Ptk2b , Ptpn11 , Ptpn6 , Ptprj , Pxn , Rac1 , Rac2 , Raf1 , RGD1560225 , RGD1565588 , Rhoa , Rock1 , Sh2d2a , Shb , Shc2 , Sphk1 , Sphk2 , Src , Vcl , Vegfa , Vegfb , Vegfc , Vegfd , Vtn
vasopressin signaling pathway via receptor type 2Prkaca
verapamil pharmacodynamics pathwayCalm1 , Prkaca
visual phototransduction pathwayCalm1 , Calm2 , Calm3
Wnt signaling pathwayChp1 , Chp1l1 , Chp2 , Ctnnb1 , Fbxw11 , Nfat5 , Nfatc2 , Nfatc3 , Nfatc4 , Ppp3ca , Ppp3cb , Ppp3cc , Ppp3r1 , Ppp3r2 , Prkaca , Prkca , Prkcb , Prkcg , Rac1 , Rac2 , RGD1560225 , RGD1565588 , Rhoa , Rock1
Wnt signaling, canonical pathwayCav1 , Ctnnb1
Wnt signaling, non-canonical pathwayCdc42 , Nfatc2 , Prkcz , Rac1 , Rhoa , Rock1
Wnt signaling, the planar cell polarity pathwayRac1 , Rhoa
Phenotype Annotations Associated with Genes in the vascular endothelial growth factor signaling pathway

References Associated with the vascular endothelial growth factor signaling pathway:

Ontology Path Diagram:
paths to the root
paths to the root

Import into Pathway Studio: